A motorcyclist was killed in a crash with a big-rig on southbound Interstate 280 in San Jose Wednesday afternoon, the California Highway Patrol confirmed.

Three lanes were closed a of 4 p.m. with no estimated time of reopening, and traffic is being allowed through in the left lane.

The crash was reported at about 3:15 p.m. just south of Race Street, according to Officer Ralph Caggiano. The Santa Clara County medical examiner's office has been called to the scene.

The motorcyclist went down for unknown reasons in between the Nos. 3 and 4 lanes, and a rock hauling truck with two trailers ran over him, according to the CHP.

The motorcyclist died at the scene, the CHP said. No other injuries were reported.

The CHP issued a Sig-alert for the fatal crash at 3:24 p.m.