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Free Press reporters were at the scene of an explosion in Old East Village in London Wednesday night. For Thursday’s teamcoverage of this developing story, visit here.

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At least two police and two firefighters were injured and a woman is in custody after a car going the wrong way on a one-way London street slammed into a home late Wednesday, leading to a major explosion that destroyed at least one Old East Village home.

London police Const. Shayna Boland said early Thursday the explosion occurred while police were investigating the initial accident after responding shortly before 11 p.m.

“There was an explosion. We believe it was due to the gas line,” Boland said. “We are actively making sure that everyone is evacuated within a one-block area.”

Boland said there were “no civilian injuries at this point.” Two police officers suffered minor injuries while two injured firefighters were “being assessed at this time,” Boland said.