The New York Giants entered this year's draft with so many questions at the safety position that they used three picks on it. They traded their second-round and fourth-round picks to move up to draft Landon Collins at the top of the second, and they spent their fifth-round pick on Mykkele Thompson.

Both rookies got hurt in the Giants' preseason opener Friday night in Cincinnati. And as they resume training camp Sunday, the Giants once again find themselves scrambling to find starting safeties.

Collins, who seemed penciled in as a Week 1 starter almost by default, sprained the MCL in his left knee Friday night, coach Tom Coughlin said Saturday. Coughlin said he didn't know how long Collins would be out, but he also said he doesn't expect him to practice this week and that missed practice time for a rookie at this stage is extremely bad.

Mykkele Thompson is taken off the field after suffering a season-ending Achilles injury. AP Photo/Frank Victores

"He needed last night," Coughlin said of Collins, who got hurt on the first defensive series of the game. "He needed it, and he didn't get much last night. He needs to be out there."

But he won't be anytime soon, and poor Thompson won't be until next offseason. His Achilles injury, Coughlin said, will keep him out for the entire season. Thompson was a long shot to start, but he'd looked good enough in camp that the Giants thought he could at least play a role.

Losing Thompson leaves the Giants thin at a spot where they had nothing but question marks. Nat Berhe continues to struggle with a calf injury, leaving Jeromy Miles, Cooper Taylor, Bennett Jackson and Justin Currie as the current options at safety.

"Those are the guys we have, and we'll get them ready to play," Coughlin said. "We've got to play some games with those guys back there and see how they do."

Cornerback Trumaine McBride suffered a hamstring injury in the game as well. He's been functioning as the nickel corner, but Coughlin said the team can play Jackson at safety on running downs and move him to nickel on passing downs (presumably bringing in Taylor at safety on those plays until Collins returns).

The Giants aren't deep at corner right now, either. Prince Amukamara (groin) and Chykie Brown (knee) missed the game with injuries, and McBride and Hosley (neck/concussion) left during the game. Coughlin said it was possible the team could add a cornerback in the coming days.