Victoria's Opposition Leader Matthew Guy says he supports in principle a call by the Andrews Government for a group of asylum seekers, due to be sent back to Nauru, to be resettled in Victoria.

In a letter released on social media last week, the Victorian Premier said the state could provide the 267 asylum seekers, including 37 children, with essential services including housing and education.

Mr Guy said he believed the state could help the group who were brought to Australia for medical treatment.

"I think there's a growing mood that we would be able to manage these people in Victoria and manage them quite well," he told 774 ABC Melbourne.

"We are talking about people's lives here and it is one that we should be very cognisant of.

"We have a proud history in this country and as a son of a refugee I think we should maintain that."

However, Mr Guy said he did not agree with the manner in which Mr Andrews had raised the issue.

"I'm not playing politics with this ... it's not about what's gathering traction or not," he said.

Victorian Premier Daniel Andrews with a child due to be sent to Nauru at Melbourne Zoo. ( Facebook: Daniel Andrews )

"This is a federal issue and the Prime Minister, [it] will be up to him and his Government to determine the best way forward."

In a Facebook post on Monday, Mr Andrews again called for the group to stay. He appeared in the post in a photo with children due to be sent back to Nauru.

"Let's do the right thing by these children and their families," Mr Andrews said.

"Let's prove that we really are a fair and decent society."

The High Court last week threw out a challenge to the legality of the Federal Government's immigration detention centre on Nauru, paving the way for the asylum seekers to be returned.

Three other state premiers have also called on the Federal Government to allow the asylum seekers to remain in Australia.

ACT Chief Minister Andrew Barr has also pledged to take more asylum seekers.

Opposition Leader Bill Shorten has called for conditions to be improved in offshore detention centres but said on Sunday that Federal Labor remained committed to regional processing.

Prime Minister Malcolm Turnbull has described the situation as "very delicate", saying the transfer of the asylum seekers will be looked at on a case-by-case basis.

Thousands of people have protested around the country this week, calling on the group to be allowed to stay.