It’s a sick prank that sent some commuters off the rails.

Two teens dressed in full-body hazmat suits pretended to spill a vat of COVID-19 on a packed Big Apple subway — leaving straphangers screaming as they fled in terror.

The pair, identified by Insider as Queens pranksters David Flores, 17, and Morris Cordewell, 19, initially sat calmly in their protective get-ups while holding a clear container with red liquid.

“I hope that’s Kool-Aid,” one passenger on the L train in Brooklyn correctly guessed — while another asked, “Is that coronavirus?”

The teens both gave thumbs-up signals while telling straphangers they were “good” — soon eliciting screams as they removed the lid of the box plastered with “WARNING” stickers.

They then pretended to fall to the floor, spilling the liquid that quickly spread down the subway carriage.

“Oh s–t!” someone shouted, while others could be heard screaming as most commuters ran away from the spill, some jumping on seats to avoid the spreading liquid in the Jan. 31 hoax.

“It’s a prank! It’s a prank!” the teens quickly reassured the screaming straphangers who feared the virus that has killed 1,113 and sickened more than 44,000 around the world.

“The first half [of the prank], people were kinda scared,” Cordewell told Insider. “After we were like, ‘Yo, it’s a prank,’ people were laughing.”

He said many on the train — including a mom and her kids next to him — “knew it was a joke the whole time,” with his sidekick, Flores, adding, “They kinda figured it out themselves.”

The MTA slammed the stunt, however, with chairman Pat Foye telling The Post that the deadly virus “is not a joking matter.”

“Given the environment, putting on hazmat suits and getting on the subway and, frankly, walking the streets of New York is an irresponsible thing to do,” Foye said.

“That kind of pranking during this particular point in time is offensive and could be dangerous.”

Still, it seemed to divide the commuters — just as it did commentators to their social media post.

“NOT funny !! Please clean the mess on your way out,” @sagardashora wrote, while @maciekkov said, “I know that is prank but they should punch their faces.”

The clip also received plenty of praise and laughing emojis. “I’m two-sided. One, it’s pretty serious right now and many people have died from the virus, but it’s good that their lifting People’s spirits and making people laugh,” @ryangerdeg wrote.

The teens understand the backlash. “To be honest, to me, I feel them, but I know it was a joke,” Flores told Insider. “At the end of the day, it was a joke.”

Related Video Video length 36 seconds :36

Other coronavirus pranks have not ended so well. James Potok, 28, landed in handcuffs after he pretended to be sick with the deadly virus in the middle of a flight from Toronto to Jamaica, forcing the plane to turn around.

The MTA told Insider that it had not been aware of the video.