Iowa voters appear a bit befuddled by Mayor de Blasio’s latest progressive battle — his fight against “toxic whiteness” in city schools.

“This is not an issue on anybody’s radar here,” said Greg Guelcher, vice-chair of the Woodbury County Democratic Club in Sioux City, which hosted Hizzoner’s first official campaign stop on May 17.

But next time the mayor drops by the Hawkeye State, he should expect Democrats to make a point of asking.

“People here will question him about it, for sure,” said Bret Nilles of the Linn County Democrats in Cedar Rapids. “We get very tuned into these candidates and the local issues they deal with as governors and mayors. We want to pose those tough questions.”

When Iowans ask, New Yorkers should listen in. The mayor’s campaign refused to respond when The Post asked whether he supports Schools Chancellor Richard Carranza’s effort to wipe out a “white-supremacy culture” among school administrators with training that blasts ideas like “individualism,” “objectivity” and “worship of the written word.”

Instead, they pointed to a Tuesday post from de Blasio’s official Twitter account — “DOE Chancellor Carranza has dedicated his entire career to fighting structural racism and giving every kid a fair shot” — as his final word on the subject.

At least four top DOE executives plan to sue over a hostile work environment toward whites, The Post reported last week.

“If that’s what is happening, and the mayor supports it, that’s a problem,” said Boston-based Democratic strategist Brad Bannon. “And he does not need any more problems than he already has.”

“Nationwide, the majority of the Democratic primary electorate is white voters,” Bannon explained. “White voters will not appreciate hearing about acts of discrimination targeting people because they are white.”

Especially in Iowa, whose first-in-the-nation caucus is a crucial test in the presidential sweepstakes. The state is 91 percent Caucasian, and most of its minority population is made up of recent immigrants from Latin America and Asia. Only 2 percent of Iowans are black.

“This year I’m hearing much more about gender equity from voters,” Nilles said. “Not so much about race.”

“For Iowans overall, if you brought up the term ‘toxic whiteness,’ people would just go, ‘Huh?’” Guelcher said. “And even after you explained it, they’d still be kind of confused.

“We’re not New York City, the multicultural paradise,” he said. “That’s great, but it ain’t Iowa.”

De Blasio’s decision to join the race as its 24th Democratic candidate — and the 14th white male — has Bannon scratching his head.

“I don’t pretend to know what the mayor’s strategy is,” he said. “If he’s looking at very liberal Democratic primary voters, they’re already nailed down for Elizabeth Warren or Bernie Sanders. If he’s targeting black voters, we already have candidates who are black.

“Most Democratic primary votes are moderates, not liberals,” Bannon said. “So if he supports reverse discrimination in the New York City schools, that’s going to mean trouble for him.”