Describe your role in one sentence. I am chief executive of the Health Research Authority, which protects and promotes the interests of patients and the public in health research.

Why did you want to work in healthcare? I can't remember not wanting to. I have worked in the NHS for over 20 years and research has always been a particular interest; so the opportunity to lead the Health Research Authority was very attractive to me.

How do you want to see the sector change in the next five years? We need to meet our commitment to ensure that every patient in the NHS has the opportunity to take part in research.

My proudest achievement at work was ... transforming the research ethics service in the UK, and being recognised for the impact this has had in making it easier to do good quality research in the NHS.

The most difficult thing I've dealt with at work is ... leading change that you know will impact on people and their roles.

The biggest challenge facing the NHS is ... removing unnecessary barriers and empowering the NHS so the UK is seen globally as the place to do health research.

The people I work with are ... genuinely appreciated.

I do what I do because ... I know it is worthwhile and I enjoy it.

Sometimes people think that I ... take a proper holiday – and occasionally I do!

Right now I want to ... see Arsenal stay top of the league and win the premiership.

At work I am always learning that ... you have to expect to be surprised by people.

If I could go back 10 years and meet my former self I'd tell them ... to be more confident sooner.

If I could meet my future self I'd expect them to be ... proud to have played my part in helping the NHS, industry and academics improve health.

What is the best part of your job? Seeing the difference we are making.

What is the worst part of your job? Seeing solutions and not always being able to implement them as soon as I would like.

What makes you smile? My family and friends, especially my two sons – their company and their achievements. I am a very proud mum.

What keeps you awake at night? Little.

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