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Kenyan Brigid Kosgei shattered a 16-year-old world record in the women’s marathon by 81 seconds, winning the Chicago Marathon in 2:14:04 on Sunday.

Brit Paula Radcliffe had held the record of 2:15:25 set at the 2003 London Marathon. Kenyan Mary Keitany holds the female-only record of 2:17:01 from the 2017 London Marathon. Both Kosgei and Radcliffe, the only women to break 2:17, ran with men in their record races.

Radcliffe’s record was the longest-standing for the men’s or women’s marathon of the last 50 years.

Kosgei did it one day after Eliud Kipchoge became the first person to run a sub-two-hour marathon in a non-record-eligible event in Vienna. She won by a gaping 6 minutes, 47 seconds over Ethiopian Ababel Yeshaneh.

Kosgei, who won Chicago in 2018 and the London Marathon in April, came in highly favored. The 25-year-old tuned up with the fastest half-marathon ever by a woman (by 23 seconds) on Sept. 8 on a non-record-eligible course.

“2:10 is possible for a lady,” Kosgei said after Sunday’s record.

Jordan Hasay, the top U.S. woman in the field, stopped after feeling a sharp hamstring strain after two miles. Hasay, who was coached by Alberto Salazar before his ban in a U.S. Anti-Doping Agency case, is one of several women in contention for the three Olympic spots at the Feb. 29 trials in Atlanta.

Kenyan Lawrence Cherono won the men’s race by one second over Ethiopian Dejene Debela in 2:05:45.

The U.S.’ top marathoner, Galen Rupp, dropped out around mile 23 after straining a calf around the sixth mile. Rupp, who was also coached by Salazar, was racing for the first time since the 2018 Chicago Marathon and Achilles surgery.

Mo Farah, the defending champion and four-time Olympic track gold medalist, finished eighth in 2:09:58. He also dropped from the leaders before the halfway point.

American Daniel Romanchuk and Swiss Manuela Schar won the wheelchair races.

Romanchuk, 21, repeated as champion. He has also won Boston London and New York City in the last year. Schar distanced decorated American Tatyana McFadden by 4:14, though McFadden did qualify for the Tokyo Paralympics with her runner-up finish (as did Romanchuk).

The fall major marathon season concludes with the New York City Marathon on Nov. 3, featuring defending champions Mary Keitany and Lelisa Desisa and 2018 Boston Marathon champion Des Linden.

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MORE: Chicago Marathon results