The billionaire hedge fund manager William Ackman deeded yet another apartment, in SoHo, to his former wife, Karen Ackman, as part of an apparent property settlement. Also, Nancy Moonves, the ex-wife of Leslie Moonves, the ousted CBS chief executive, traded one Upper East Side co-op for another around the corner.

And in Chelsea, the screenwriters Henry Bean and Leora Barish sold a townhouse with a private yoga studio.

The limestone-and-red brick mansion on East 74th Street, sold by Mr. Lasry, sits on one of the neighborhood’s most desired streets, between Fifth and Madison Avenues. It was designed at the turn of the 20th century by Alexander Welch and built for Francis Lynde Stetson and his wife, Elizabeth Ruff Stetson. Stetson was a law partner with Grover Cleveland between Cleveland’s two split terms as president.

Over the years, many residents have come and gone from the mansion, including Chagall, who lived on the top floor with his wife, the writer Bella Chagall, shortly after arriving in New York in 1941. They decorated their apartment with his artwork. Jackson rented the house for six months, from August 1999 to February 2000. (The asking rent was $75,000 a month in 1998.)

The building also has been featured on the big and small screens. It appeared in the 1991 film “The Prince of Tides,” starring Barbra Streisand, and more recently, had a recurring role in the “Gossip Girl” TV series that ran from 2007 to 2012.

The stately structure is 25 feet wide, with nearly 12,750 square feet of interior space including seven bedrooms, eight full baths, two half baths and staff quarters in the finished basement. Although the home was extensively renovated, many original architectural flourishes remain, like the high ceilings, detailed oak staircase, 10 wood-burning fireplaces, and wood floors, paneling and moldings. The exterior includes a private roof deck and a patio on the garden level.

Monthly taxes are nearly $10,000. Adam D. Modlin and Nina Tkachuk Perez of the Modlin Group were the listing brokers; Mr. Modlin also represented the buyer.