Chemotherapy, radiotherapy, and immunotherapy are typically used to treat cancer, but they do not work for all patients with the disease. In a new study, scientists have discovered a cancer-killing technique that might be more effective than conventional cancer therapies.

Share on Pinterest Researchers have discovered a potentially more effective way to kill cancer cells.

Researchers reveal how a process called caspase-independent cell death (CICD) frequently led to the complete eradication of colorectal cancer cells, which is not often the case with current cancer treatments.

Study co-author Dr. Stephen Tait, of the Cancer Research UK Beatson Institute at the University of Glasgow in the United Kingdom, and colleagues recently reported their findings in the journal Nature Cell Biology.

Cancer remains one of the biggest health burdens of our time. Last year, more than 1.6 million new cases were diagnosed in the United States alone, and almost 600,000 people died from the disease.

Dr. Tait and team explain that the majority of current cancer therapies work by inducing apoptosis. Apoptosis is a form of programmed cell death, or cell suicide, that helps to rid the body of abnormal or unnecessary cells by activating proteins called caspases. In cancer cells, however, apoptosis is often inactive.

Reactivating apoptosis in cancer cells – through chemotherapy or immunotherapy, for example – is one way of killing them. But this is not always effective.

Research has shown that cancer cells are sometimes able to evade treatment-induced apoptosis, and some studies have suggested that apoptosis may even promote cancer growth.

CICD, however, takes cancer killing one step further, and Dr. Tait and team suggest that it may be a more effective way to treat cancer than current therapies.