9:46pm: Besides Braun and Rodriguez, "other major, major names" are also involved in the Biogenesis case, a source tells Bob Klapsich of the Bergen Record (Twitter link).

6:56pm: Major League Baseball is planning to suspend at least 20 players connected to Biogenesis, the Miami clinic under investigation for supplying performance-enhancing drugs, reports T.J. Quinn, Pedro Gomez and Mike Fish of ESPN's Outside The Lines. Biogenesis founder Tony Bosch has agreed to cooperate with the investigation and begin naming players, with suspensions possibly following within two weeks.

The list of possible suspensions includes Alex Rodriguez, Ryan Braun, Melky Cabrera, Nelson Cruz, Bartolo Colon, Yasmani Grandal, Francisco Cervelli, Jesus Montero, Jhonny Peralta, Cesar Puello, Fernando Martinez, Everth Cabrera, Fautino de los Santos and Jordan Norberto, plus others who are named in documents that the ESPN team haven't had access to, or are known under code names.

MLB officials have also investigated a possible connection between Biogenesis and Yankees second baseman Robinson Cano, as the spokeswoman for Cano's foundation (Sonia Cruz) has had her name appear in some clinic documents. Nationals southpaw Gio Gonzalez isn't expected to face suspension for his connection to Biogenesis since the products he obtained from the clinic weren't banned.

The league could look for a 100-game suspension (the penalty for second-time PED offenders) for Rodriguez, Braun and other first-time offenders since both the connection to Biogenesis and previous denials to MLB officials would serve as seperate offenses. It is unknown how MLB would deal with players like Cabrera or Colon who already have PED suspensions on their record, though these players probably wouldn't face a lifetime ban as three-time offenders — their prior suspensions would likely count as their so-called "first strike," with this next violation putting them in line for 100-game suspensions as well.

Quinn/Gomez/Fish report that, as expected, the accused players will challenge any possible suspensions and it could be difficult for the league to obtain corroborating evidence in the appeals process beyond Bosch's testimony.