The first fatality of Fairfax Media's newspaper shake-up in South Australia occurs today when the Roxby Downs Sun goes to print for the last time.

Budget cuts to Fairfax newspapers have already squeezed the life out of several regional and agricultural newspapers this decade but in July the company announced further cuts to "revitalise" its business.

It included the loss of 34 full-time jobs in the state's regional newspapers, including 21 positions in editorial roles.

It included discontinuing the Roxby Downs Sun and reducing the Whyalla News to a weekly publication instead of a being published twice a week.

Labor MP for Giles Eddie Hughes said the decision to axe the Sun was disappointing and meant the outback mining town would lose its only independent newspaper.

"It had a bit of a streak of independence, which I think will be sorely missed," he said.

"It also played a role where it was willing to ask questions about what was going on there locally."

Fairfax said the newspaper's axing and state-wide redundancies were part of an 18-month overhaul of its Community Media division and that it would invest in a digital-first publishing system to redesign its newspapers.

The company has already cut about 120 jobs from papers in regional Victoria and New South Wales.

The Media, Entertainment and Arts Alliance said at the time of the announcements that news coverage in country communities would be negatively affected by the cuts.