An influential doctors group is calling on the Berejkilian government to introduce a minimum price on alcohol in a bid to reduce drinking related harm in NSW.

The Royal Australasian College of Physicians has weighed in to Sydney's lockout laws debate, urging the state government not only to retain the laws and also tighten the availability of alcohol.

The Royal College of Physicians says NSW needs to rethink its approach to alcohol. Credit:Sahlan Hayes

A NSW parliamentary inquiry into the city's night-time economy is underway after Premier Gladys Berejiklian said it was time to "revisit" the controversial lockout laws introduced in 2014.

In a submission to the inquiry, the physicians say "a special emphasis" on maintaining restricted trading hours for licensed venues in Kings Cross and the CBD was necessary.