Donald Trump knocked $6 billion off of Amazon before most of the country was awake.

In a tweet sent at 6:12 a.m. EST, Trump claimed Amazon was "doing great damage to tax paying retailers," resulting in the loss of jobs.

Amazon is doing great damage to tax paying retailers. Towns, cities and states throughout the U.S. are being hurt - many jobs being lost! — Donald J. Trump (@realDonaldTrump) August 16, 2017

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That immediately sent Amazon shares down sharply, resulting in a decline of around $6 billion of the company's market capitalization in a matter of minutes.

Image: Google finance

Such is the power of Trump's tweets.

The move isn't life threatening for Amazon, which is still worth in excess of $460 billion. It does, however, highlight growing concern that Trump may be willing to target Amazon, which has already stirred rumblings about the need for greater regulation to limit the company's growing power.

RELATED: US states with the highest and lowest Trump job approval ratings:

34 PHOTOS States with the highest and lowest Trump job approval ratings See Gallery States with the highest and lowest Trump job approval ratings Idaho Approval rating: 50% or higher (Photo via Getty Images) Utah Approval rating: 50% or higher (Photo via Getty Images) Montana Approval rating: 50% or higher (Photo via Getty Images) Wyoming Approval rating: 50% or higher (Photo via Getty Images) North Dakota Approval rating: 50% or higher (Photo by Ben Harding via Getty Images) South Dakota Approval rating: 50% or higher (Photo via Getty Images) Nebraska Approval rating: 50% or higher (Photo via Getty Images) Kansas Approval rating: 50% or higher (Photo via Shutterstock) Oklahoma Approval rating: 50% or higher (Photo via Getty Images) Arkansas Approval rating: 50% or higher (Photo via Getty Images) Louisiana Approval rating: 50% or higher (Photo via Getty Images) Alabama Approval rating: 50% or higher (Photo via Getty Images) South Carolina Approval rating: 50% or higher (Photo by Sean Pavone via Getty Images) Tennessee Approval rating: 50% or higher (Photo via Getty Images) Kentucky Approval rating: 50% or higher (Photo via Getty Images) West Virginia Approval rating: 50% or higher (Photo by Stan Rohrer via Getty Images) Alaska Approval rating: 50% or higher (Photo via Getty Images) Massachusetts Approval rating: Below 40% (Photo via Getty Images) Vermont Approval rating: Below 40% (Photo via Getty Images) Rhode Island Approval rating: Below 40% (Photo by Kenneth C. Zirkel via Getty Images) Connecticut Approval rating: Below 40% (Photo via Getty Images) New Jersey Approval rating: Below 40% (Photo via Getty Images) New York Approval rating: Below 40% (Photo via Getty Images) Delaware Approval rating: Below 40% (Photo via Getty Images) Maryland Approval rating: Below 40% (Photo via Getty Images) Virginia Approval rating: Below 40% (Photo via Getty Images) Illinois Approval rating: Below 40% (Photo via Getty Images) Minnesota Approval rating: Below 40% (Photo via Getty Images) Colorado Approval rating: Below 40% (Photo via Getty Images) New Mexico Approval rating: Below 40% (Photo via Getty Images) Washington Approval rating: Below 40% (Photo via Getty Images) Oregon Approval rating: Below 40% (Photo via Getty Images) California Approval rating: Below 40% (Photo via Getty Images) Hawaii Approval rating: Below 40% (Photo via Getty Images) Up Next See Gallery Discover More Like This HIDE CAPTION SHOW CAPTION of SEE ALL BACK TO SLIDE

STOCK PRICE FOR AMZN

Amazon began to draw Trump's ire in late 2015 due to CEO Jeff Bezos's ownership of the Washington Post, which aggressively reported on the Trump campaign.

Trump went after Bezos, claiming that his ownership of the Post was so that he could reduce Amazon taxes. This wouldn't work, since the Post and Amazon are two entirely separate companies.

The @washingtonpost, which loses a fortune, is owned by @JeffBezos for purposes of keeping taxes down at his no profit company, @amazon. — Donald J. Trump (@realDonaldTrump) December 7, 2015

That was just the beginning. Since then, Trump has on three other occasions launched tweets at Amazon, including the time the president threatened Amazon with an 'internet tax.'

The #AmazonWashingtonPost, sometimes referred to as the guardian of Amazon not paying internet taxes (which they should) is FAKE NEWS! — Donald J. Trump (@realDonaldTrump) June 28, 2017

Trump's latest tweet on Wednesday appears to have been spurred by a Washington Post editorial published Tuesday night entitled "The nation can only weep," which calls out Trump's response after Charlottesville.

RELATED: Check out the state of the New York Stock Exchange before Trump took office:

11 PHOTOS New York Stock Exchange before the election See Gallery New York Stock Exchange before the election Traders work on the floor of the New York Stock Exchange (NYSE) in New York City, U.S., November 7, 2016. REUTERS/Brendan McDermid Traders work on the floor of the New York Stock Exchange (NYSE) in New York City, U.S., November 7, 2016. REUTERS/Brendan McDermid Traders work on the floor of the New York Stock Exchange (NYSE) in New York City, U.S., November 7, 2016. REUTERS/Brendan McDermid Traders work on the floor of the New York Stock Exchange (NYSE) in New York City, U.S., November 7, 2016. REUTERS/Brendan McDermid Traders work on the floor of the New York Stock Exchange (NYSE) in New York City, U.S., November 3, 2016. REUTERS/Brendan McDermid Pedestrians walk along Wall Street near the New York Stock Exchange (NYSE) in New York, U.S., on Monday, Oct. 31, 2016. U.S. stocks rose from a six-week low amid an increase in deal activity as traders assessed the outlook for the presidential election and interest rates in the world's largest economy. Photographer: Michael Nagle/Bloomberg via Getty Images NEW YORK, NY - NOVEMBER 01: Traders work on the floor of the New York Stock Exchange (NYSE) on November 1, 2016 in New York City. As Wall Street continues to feel election uncertainty, the Dow Jones closes fell more than 100 points. (Photo by Spencer Platt/Getty Images) A trader works on the floor of the New York Stock Exchange (NYSE) in New York, U.S., on Friday, Nov. 4, 2016. U.S. stocks fluctuated amid payrolls data that bolstered speculation the economy is strong enough to weather higher interest rates, while investors remained wary before the looming presidential election. Photographer: Michael Nagle/Bloomberg via Getty Images Traders work on the floor of the New York Stock Exchange (NYSE) in New York, U.S., on Friday, Nov. 4, 2016. U.S. stocks fluctuated amid payrolls data that bolstered speculation the economy is strong enough to weather higher interest rates, while investors remained wary before the looming presidential election. Photographer: Michael Nagle/Bloomberg via Getty Images NEW YORK, NY - NOVEMBER 01: Traders work on the floor of the New York Stock Exchange (NYSE) on November 1, 2016 in New York City. As Wall Street continues to feel election uncertainty, the Dow Jones closes fell more than 100 points. (Photo by Spencer Platt/Getty Images) A trader works on the floor of the New York Stock Exchange (NYSE) in New York, U.S., on Monday, Oct. 31, 2016. U.S. stocks rose from a six-week low amid an increase in deal activity as traders assessed the outlook for the presidential election and interest rates in the world's largest economy. Photographer: Michael Nagle/Bloomberg via Getty Images Up Next See Gallery Discover More Like This HIDE CAPTION SHOW CAPTION of SEE ALL BACK TO SLIDE

"That car in Charlottesville did not kill or wound just the 20 bodies it struck. It damaged the nation. Mr. Trump not only failed to help the country heal; he made the wound wider and deeper," the Post editorial wrote.​​​​​​

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