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Two men have been arrested in the gruesome quadruple murder in upstate New York that left four people dead — two of them children.

Cops say Justin C. Mann, 24, and James W. White, 38, both of Schenectady, were arrested late Friday, the Albany Times Union reported.

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Police sources told the newspaper that one of the suspects was acquainted with one of the dead women. Both men have criminal records and Mann was on parole.

The duo appeared in Troy City Court and were both arraigned on one count of first-degree murder and four counts of second-degree murder.

According to detectives, Shanta Myers, 36, two of her three children, 11 and 5, and her girlfriend Brandi Mells, 22, were found with their hands and ankles bound and their slit throats on Tuesday.

However, cops believe the murders occurred on Dec. 21 about 9 p.m.

The Times Union reported that the two children were discovered together, kneeling with their heads and chests on a bed. One of the women was found dead on a mattress on the floor while the other was nearby, face down and covered with a sheet.