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As would George's wildly uncharacteristic act at the end of the episode in which, upon learning he may have gotten a woman pregnant himself, he puts the woman's needs ahead of his own. He's extremely excited to find out that he is able to impregnate someone, but this joy goes past the basic pride that comes from knowing that you have proactive sperm. He rushes to her and promises to do whatever he can to take care of the baby, only to be told by the woman that she just got her period. A man discovers that he still may never have offspring or anything that will unconditionally love him. The signature Seinfeld bass line plays. Comedy!

NBC

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"That's gotta hurt!"

So it could be deduced that his brother's impregnation mistake prompts George to handle his own differently and that the grief of his brother's passing makes him shift in personality and become a lot more caring and empathetic, even if momentarily. It takes a hell of a lot for something to make George act un-George-like, but trying to right a wrong of that magnitude could possibly do it.