A dozen people were injured Wednesday night when a car struck a pedal-powered pub in downtown Minneapolis.

The Twin Cities PedalPub was heading south on the Hennepin Avenue Bridge just before 10 p.m. when it was rear-ended by a Chevrolet Monte Carlo, according to a Minneapolis police spokesman.

The PedalPub tipped over, pinning several of the riders. Passers-by lifted the PedalPub back onto its wheels, freeing the riders.

Twelve PedalPub passengers were taken to the hospital. Three had “significant” injuries, police later said via Twitter.

The driver of the car remained on the scene and was arrested after being interviewed by police.

Authorities were investigating whether alcohol was a factor in the crash.

Further information on the extent of injuries was not immediately available Wednesday night.

The southbound lanes of the bridge leading into downtown were closed while the investigation continued.

Pedal-powered bars operated by the same company were involved in high-profile May attacks on the vehicles by bicyclists hurling water balloons and wielding water guns.

Earlier this week, Minneapolis prosecutors dismissed most of the charges filed in connection with the attacks.

City Attorney Susan Segal said there wasn’t enough evidence to continue with the cases against four men.

Minnesota Public Radio News said that during a hearing Tuesday, Segal said prosecutors couldn’t match up individuals with the conduct. However, a fifth man still faces fifth-degree assault and disorderly conduct charges, and a sixth man could also be charged.

The men were allegedly involved in two attacks on PedalPubs in May. One of the pubs had six off-duty Burnsville police officers on board, and they eventually helped to detain the assailants.

There were no injuries. But a Twin Cities PedalPub manager said the attacks were potentially dangerous to the vehicles’ drivers and passengers.

Pedal-powered pubs have been criticized by some for impeding traffic and leading to rowdy passenger behavior.

Jaime DeLage can be reached at 651-228-5450. Follow him at twitter.com/JaimeDeLage.