1. Dore, J. E., Lukas, R., Sadler, D. W., Church, M. J. & Karl, D. M. Physical and biogeochemical modulation of ocean acidification in the central North Pacific. Proc. Natl Acad. Sci. USA 106, 12235–12240 (2009).

2. Santana-Casiano, J. M., Gonzalez-Davila, M., Rueda, M. J., Llinas, O. & Gonzalez-Davila, E. F. The interannual variability of oceanic CO 2 parameters in the northeast Atlantic subtropical gyre at the ESTOC site. Glob. Biogeochem. Cycle 21, GB1015 (2007).

3. Bates, N. R. Interannual variability of the oceanic CO 2 sink in the subtropical gyre of the North Atlantic Ocean over the last 2 decades. J. Geophys. Res.-Oceans 112, C09013 (2007).

4. Lui, H. K. & Chen, C. T. A. Deducing acidification rates based on short-term time series. Sci. Rep. 5, 11517 (2015).

5. Le Quere, C., Takahashi, T., Buitenhuis, E. T., Rodenbeck, C. & Sutherland, S. C. Impact of climate change and variability on the global oceanic sink of CO 2 . Glob. Biogeochem. Cycle 24, GB4007 (2010).

6. Ridgwell, A. & Schmidt, D. N. Past constraints on the vulnerability of marine calcifiers to massive carbon dioxide release. Nat. Geosci. 3, 196–200 (2010).

7. Thomas, E. Ocean acidification – How will ongoing ocean acidification affect marine life? (Past). PAGES news 20, 37 (2012).

8. Kleypas, J. A. & Yates, K. K. Coral reefs and ocean acidification. Oceanography 22, 108–117 (2009).

9. Barry, J. P., Buck, K. R., Lovera, C., Kuhnz, L. & Whaling, P. J. Utility of deep sea CO 2 release experiments in understanding the biology of a high-CO 2 ocean: Effects of hypercapnia on deep sea meiofauna. J. Geophys. Res. Oceans https://doi.org/10.1029/2004jc002629 (2005).

10. Riebesell, U. & Tortell, P. D. in Ocean Acidification (eds Gattuso J. P. & Hansson L.) 99–121 (Oxford Univ. Press, Oxford, 2011).

11. Gattuso, J. P. Ocean acidification – How will ongoing ocean acidification affect marine life? Present. PAGES news 20, 36 (2012).

12. Feely, R. A. & Chen, C. T. A. The effect of excess CO 2 on the calculated calcite and aragonite saturation horizons in the Northeast Pacific. Geophys. Res. Lett. 9, 1294–1297 (1982).

13. Feely, R. A. et al. Impact of anthropogenic CO 2 on the CaCO 3 system in the oceans. Science 305, 362–366 (2004).

14. Sabine, C. L. et al. The oceanic sink for anthropogenic CO 2 . Science 305, 367–371 (2004).

15. Feely, R. A. et al. The combined effects of ocean acidification, mixing, and respiration on pH and carbonate saturation in an urbanized estuary. Estuar. Coast. Shelf Sci. 88, 442–449 (2010).

16. Cai, W. J. et al. Acidification of subsurface coastal waters enhanced by eutrophication. Nat. Geosci. 4, 766–770 (2011).

17. Senjyu, T. et al. Benthic front and the Yamato Basin Bottom Water in the Japan Sea. J. Oceanogr. 61, 1047–1058 (2005).

18. Gamo, T. Global warming may have slowed down the deep conveyor belt of a marginal sea of the northwestern Pacific: Japan Sea. Geophys. Res. Lett. 26, 3137–3140 (1999).

19. Chen, C. T. A., Bychkov, A. S., Wang, S. L. & Pavlova, G. Y. An anoxic Sea of Japan by the year 2200? Mar. Chem. 67, 249–265 (1999).

20. Kim, K. et al. Warming and structural changes in the East (Japan) Sea: A clue to future changes in global oceans? Geophys. Res. Lett. 28, 3293–3296 (2001).

21. Watanabe, Y. W., Wakita, M., Maeda, N., Ono, T. & Gamo, T. Synchronous bidecadal periodic changes of oxygen, phosphate and temperature between the Japan Sea deep water and the North Pacific intermediate water. Geophys. Res. Lett. 30, 2273 (2003).

22. Chen, C. T. A. & Wang, S. L. Carbonate chemistry of the sea of Japan. J. Geophys. Res.-Oceans 100, 13737–13745 (1995).

23. Wong, G. T. F. & Li, K.-Y. Winkler’s method overestimates dissolved oxygen in seawater: Iodate interference and its oceanographic implications. Mar. Chem. 115, 86–91 (2009).

24. Hatta, M. & Zhang, J. Possible source of advected water mass and residence times in the multi-structured Sea of Japan using rare earth elements. Geophys. Res. Lett. 33, L16606 (2006).

25. Chen, C. T. A., Gong, G. C., Wang, S. L. & Bychkov, A. S. Redfield ratios and regeneration rates of particulate matter in the Sea of Japan as a model of closed system. Geophys. Res. Lett. 23, 1785–1788 (1996).

26. Park, G.-H., Lee, K. & Tishchenko, P. Sudden, considerable reduction in recent uptake of anthropogenic CO 2 by the East/Japan Sea. Geophys. Res. Lett. 35, L23611 (2008).

27. Park, G.-H. et al. Large accumulation of anthropogenic CO 2 in the East (Japan) Sea and its significant impact on carbonate chemistry. Glob. Biogeochem. Cycle, 20, BG4013 (2006).

28. Millero, F. J. The marine inorganic carbon cycle. Chem. Rev. 107, 308–341 (2007).

29. Kim, T. W. et al. Prediction of Sea of Japan (East Sea) acidification over the past 40 years using a multiparameter regression model. Glob. Biogeochem. Cycle 24, GB3005 (2010).

30. Byrne, R. H., Mecking, S., Feely, R. A. & Liu, X. Direct observations of basin-wide acidification of the North Pacific Ocean. Geophys. Res. Lett. 37, L02601 (2010).

31. Chen, C. T. in Solubility Data Series Vol. 7 Oxygen and Ozone (ed. Battino R.) 41-55 (Pergamon Press, London, 1981).

32. Pierrot, D., Lewis, E. & Wallace, D. W. R. MS Excel Program Developed for CO2 System Calculations. ORNL/CDIAC-105a (Carbon Dioxide Information Analysis Center, Oak Ridge National Laboratory, US Department of Energy, Oak Ridge, Tennessee, 2006).

33. Lueker, T. J., Dickson, A. G. & Keeling, C. D. Ocean pCO 2 calculated from dissolved inorganic carbon, alkalinity, and equations for K 1 and K 2 ; validation based on laboratory measurements of CO 2 in gas and seawater at equilibrium. Mar. Chem. 70, 105–119 (2000).

34. Dickson, A. G., Sabine, C. L. & Christian, J. R. Guide to Best Practices for Ocean CO 2 Measurements PICES Special Publication, 3 (Sidney, British Columbia, North Pacific Marine Science Organization, 2007).

35. Orr, J. C., Epitalon, J.-M. & Gattuso, J.-P. Comparison of ten packages that compute ocean carbonate chemistry. Biogeosciences 12, 1483–1510 (2015).