Nathalie Emmanuel may be the world’s most famous sidekick as Daenerys’ right-hand woman, Missandei, on “Game of Thrones” — but now the spotlight shines on her in Hulu’s “Four Weddings and a Funeral.”

Created by Mindy Kaling, the 10-episode series, premiering Wednesday, follows four ex-college friends through romantic triumphs and setbacks in London.

“I was attracted to the role of Maya because she and I share some things in common, such as being women in often male-dominated spaces and white-dominated spaces,” says the British-born Emmanuel. “You have to have a certain savviness, and I love that about her. And as a woman growing up figuring out life and love and friendship— it’s messy. You don’t always get it right.”

Although it shares a name and a concept with the classic 1994 movie starring Hugh Grant and Andie MacDowell, “Four Weddings” is not a remake or a reboot. Emmanuel refers to it as a “re-imagining.” The show’s story and characters are new; the main link to the film is its plot structure.

Maya begins the show as a political speechwriter in an ill-fated affair with the married senatorial candidate she’s working for (Tommy Dewey, “Code Black”). When she goes to London to attend a friend’s wedding she has a meet-cute in the airport with nice guy Kash (Nikesh Patel, “Indian Summers”). The catch? Unbeknownst to them both, Kash is her friend’s fiance. Misunderstandings and heartache ensue.

Patel, who’s British-Indian, says that he was intrigued by the prospect of playing a romantic lead, since that’s been a role primarily for caucasian actors in the past.

“My first reaction when the script turned up … was, ‘Oh, they’re doing ‘Four Weddings and a Funeral’ with a diverse cast, why hasn’t this been done sooner?’ ” he says. “I think that the romcom genre—as beloved as it is— hasn’t been as inclusive as it could be. What was really exciting about playing Kash was that it felt like there wasn’t much of a precedent for that character. There was something really exciting about inhabiting somebody who felt close to me. [Like Kash], I’m a Londoner, born and raised. I know what it’s like to come from a tight-knit family background which has its own set of values.”

Emmanuel’s perpetually hassled Maya is a more classic romcom archetype. But her main inspiration was not Grant in the original “Four Weddings” but Julia Roberts. “I’m just a huge fan of Julia Roberts and I feel like she’s such a feisty woman in a lot of her roles, as well as having a vulnerability and emotional range,” she says. “I didn’t necessarily model my character on her, but I very much wanted to bring some of it to [Maya]. Especially in ‘My Best Friend’s Wedding,’ [Roberts is] in a sticky situation and I couldn’t help but find the parallels between that and Maya’s situation.”

Emmanuel and Nikesh were both too young to see the original “Four Weddings” when it first came out in 1994, but Nikesh says it plays into one of his early childhood memories. “I was aware of it growing up. I’ve got a memory of being home, playing in the living room and my mum had it on. And swearing was not permitted in my house, and the movie begins with [the f-word] being said over and over by Hugh Grant. I remember even at that young age, being like, ‘What is my mom watching?’ but then she started laughing. And I thought, ‘Well, there’s something quite magic about that.’ ”