But the company, governed by a diverse collective of actors, writers, directors and designers, has for years debated how best to make artistic decisions, and those arguments have continued unabated.

“I was craving making a bigger impact, and they were wanting to be more company-centric, and it became clear to me that we weren’t lined up,” Ms. O’Donnell said. “But everyone is rooting for the company to succeed and to figure out the next chapter of Labyrinth’s history.”

Ms. O’Donnell said her departure was “absolutely voluntary — completely my decision,” and that she was looking forward to spending the summer with her three children and taking some time to figure out what comes next. “I’m ready for something new,” she said. “I love theater. But the world is big.”

The company has one project remaining this season — a site-specific staging of “This Is Reading,” by Lynn Nottage, in Reading, Pa. The project, a multimedia installation inspired by the research that led to Ms. Nottage’s Pulitzer Prize-winning “Sweat,” is scheduled to take place next month.

A Labyrinth co-founder, John Ortiz, and a company member, Elizabeth Canavan, plan to lead the theater while searching for a new artistic director. The company has not announced a new season; its website says simply “check back soon for news about our next exciting project.”