San Diego Chargers running back Melvin Gordon may be held out of his team's second preseason game Saturday against the Arizona Cardinals due to an ankle injury, according to NFL.com's Rand Getlin.

Gordon was selected with the Chargers' first-round pick in 2015. The former Wisconsin star is expected to become the team's opening day starter.

Although he set a number of NCAA rushing records, Gordon's transition to the NFL may not be seamless. In the Chargers' first preseason game, Gordon rushed for a paltry 11 yards on six carries.

Branden Oliver and Danny Woodhead could see more carries if Gordon doesn't suit up Saturday.