A man is in a critical condition after setting himself on fire at Crown casino in an incident which injured three other people.

A Victoria Police spokeswoman said the man sustained burns after allegedly setting himself alight just after 3pm on Friday – but that his identity and the exact circumstances of the incident were yet to be determined.

Three Crown security staff suffered minor injuries trying to help a man who set himself on fire at the casino, a spokeswoman said. Credit:Jason South

An Ambulance Victoria spokesman said he was rushed from Southbank to The Alfred hospital in a serious condition on Friday afternoon for burns treatment.

A second man in his 40s was taken to the same hospital in a stable condition with burns to hands, the spokesman said.