“It’s a pity it’s so commercial now,” Mr. Pellat-Finet said. For more than five years, he has splashed oversize skull graphics — sporting, say, Mickey Mouse ears — on his sweaters. “Maybe Wal-Mart will replace their smiley-face with a tête de mort,” he added, using the French term for skull. “It’s lost its meaning.”

Well, it still has one meaning for Mr. Pellat-Finet, whose latest skull sweaters are embellished with Afros and top hats, among other images. Asked if he will stop using the motif, he responded with a chuckle: “No, no, no. It’s my best seller!”

Image Alexander McQueens silk scarf is a best seller. Credit... Lars Klove for The New York Times

Other designers appear to have similarly mixed feelings: on one hand, they are confronted with skull saturation; on the other, skulls are ringing the dinner bell louder than ever. Alexander McQueen’s fall men’s wear show did not play up skull imagery on the runway — surely the critics would be bored — but there are plenty back in the showroom, on sports coats, polo shirts and trousers. His $210 skull-print silk scarf is one of the best-selling items on the men’s designer floor at Barneys New York.

“We’ve sold 400 since May,” said Timothy Elliott, a Barneys spokesman. “We sell them as fast as they come in.”

Many people point to the “Pirates of the Caribbean” franchise as fuel for skullmania. But the skull’s ascent to the logo throne has more to it and behind it than a Disney marketing campaign. Reminiscent of the vogue for angels a decade or more ago — remember how the little winged creatures were everywhere? — the skull neatly encapsulates a cultural moment in terms both precise and vague.