MINNEAPOLIS -- Sure, the New York Yankees stumbled through September as Andy Pettitte tried to work his way back from a groin injury.

After landing in the AL wild-card spot, the defending World Series champs look as though they had the Minnesota Twins right where they wanted 'em.

Pettitte turned in a vintage performance with seven smooth innings and Lance Berkman had two big hits in a 5-2 victory by the Yankees over their favorite postseason punching bag on Thursday evening for a 2-0 lead in the best-of-five division series.

So much for Minnesota's home-field advantage. The Yankees are hardly an underdog when it comes to October.

"Andy, when he gets in big situations, he knows how to handle it," New York manager Joe Girardi said. "He's not going to try to make the perfect pitch. He's going to stay aggressive and just try to do what he does. And I think a lot of that is just from experience."

Berkman hit a go-ahead home run in the fifth and a tiebreaking double in the seventh against Carl Pavano, sending the Twins to their 11th straight postseason loss. Eight of those have come against the Yankees, who trailed in each of those games.

From the point of the Twins' biggest lead in those games, the Yankees have outscored them 42-8.

Mariano Rivera got three outs for his second save of the series, extending his postseason record to 41 and running his career total to 600, including 559 in the regular season. The road team has won all four games in the two AL playoff series.

The Twins? They haven't won a postseason game since 2004, matching the Philadelphia Phillies (1915-1976) for the second-longest streak in history behind the Boston Red Sox (1986-1995) and their 13th in a row.

Berkman, yet another big-name veteran finding a place on a Yankees postseason roster, even on the downside of his career, made it 2-1 with his drive into the left-center bullpen in the fifth. His double in the seventh -- one pitch after it appeared Pavano sneaked strike three past him -- drove in Jorge Posada and gave the Yankees a 3-2 lead.