Brisbane-based researchers hope to start human trials this year on a needle-less patch with the potential to transform vaccination, thanks to a $25 million funding boost.

The company behind the tiny Nanopatch aims to revolutionise vaccination by tackling three of the main difficulties with the process.

Brisbane scientist Professor Mark Kendall and his team invented the Nanopatch. Credit:Kendall/D2G2 group

Most simply, instead of a needle it uses thousands of microscopic points to inject vaccines directly into immune cells in the skin, removing a barrier for an estimated 10 per cent of the population with needle phobia.

Potentially more groundbreaking is a cost-saving 100-fold reduction in the necessary dose and removing the need for refrigeration.