Both sides defied baking conditions at Suncorp Stadium in an enthralling end-to-end contest, but the Glory's silkier movement and finishing enabled them to notch a second straight big win to open the new season.

They beat perennial title contenders Melbourne City by the same scoreline last weekend.

In another statement of intent from the Glory, American import Hill was the star of the show with three goals while Matildas superstar Samantha Kerr chipped in with a second-half penalty.

Hill's first came just minutes after Roar custodian Mackenzie Arnold denied her a certain goal with a point-blank save.

She fired home from close range after a turnover in the 42nd minute.

Brisbane responded almost instantly, taking advantage when a long-range free kick from Katrina Gorry slipped straight through the hands of goalkeeper Melissa Maizels and onto the crossbar.

Captain Claire Polkinghorne bundled onto the rebound and it trickled over the line after hitting striker Wai Ki Cheung, making it 1-1 at half-time.

Hill popped up again on the hour mark, tucking home when Maizels parried a shot from Raquel Rodriguez right at her feet.

It was 3-1 in the 77th minute, when Kerr drew a penalty off Arnold and then converted it herself.

And Hill completed the rout seven minutes from time with a low, perfectly-angled shot that found the bottom corner and had Maizels totally beaten.

Perth now lead the W-League after two rounds, just ahead of the Newcastle Jets - the only other unbeaten team - on goal difference.

The Jets toppled Sydney FC 2-0 at home on Saturday, condemning the Sky Blues to their second consecutive defeat with goals from Nicola Orgill and Arin Gilliland.

The Western Sydney Wanderers left it late in their clash with Adelaide United, who were playing their first game of the season after sitting out the opening round with the bye.

Rosie Sutton scored in the 91st minute when a deflected free kick fell her way, firing it into the back of the net to send the fans at Marconi Stadium wild.

Friday night's Melbourne derby was also decided late, with Melbourne City beating Melbourne Victory 1-0 courtesy of an 83rd-minute header from Rebekah Stott.