Intracutaneous Microneedle System

What is the intracutaneous microneedle system?

The system is a single-entity combination product, which comprises a reusable applicator and a microneedle array containing patch, for intracutaneous drug delivery allowing rapid absorption into the bloodstream. The microneedle array patch is applied to the skin using a ready to use and reusable handheld applicator.

Each microneedle array patch is individually packaged and stored at room temperature.

How does it work?

An array of close to two thousand drug-coated titanium microneedles is mounted on the skin-facing surface of a backing that resembles an adhesive bandage. The length of each individual microneedle is about 3 times the width of a human hair.

When the microneedle patch is applied, the microneedles penetrate the outermost layer of the epidermis (stratum corneum). The shallow depth of penetration limits the likelihood of stimulating sensory nerve endings and causing pain. Interstitial fluid in the skin reconstitutes the drug and makes it available for rapid absorption into the bloodstream.

What are the advantages of intracutaneous delivery?