The collapse of another Adelaide home builder - the seventh in as many months - could be the biggest in recent history.

And many tradies and creditors claim they will not survive after months of industry turmoil.

Coast to Coast is the latest in a growing number of local companies that have collapsed in the past year, following the demise of electronics giant Radio Rentals.

Coast to Coast Homes' former office at Croydon Park. Credit: 7NEWS

The South Australian company's liquidation looks set to leave 90 homes partially built and unlikely to be finished any time soon.

The two company directors were nowhere to be seen on Friday as liquidators were appointed.

Plumber Toby Bowman has told 7NEWS he believes every contractor is owed money, but the company has not been answering their calls.

"If I was one of those company directors, I'd go into hiding," he said.

The previous tenant of Coast to Coast's office, McCracken Homes, went broke back in 2013.

'Big problem'

Building indemnity insurer QBE says there have already been 20 claims from panicked customers.

It is unclear at this stage how much the company, which began in Moonta in 2010, owes creditors.

South Australian treasurer Rob Lucas has acknowledged the closure could be a sign of looming collapse.

"There's every likelihood this could be a big problem in terms of the impact on potential home owners," Lucas said.

Fifteen staff are likely to lose their jobs as of Friday.

The Master Builders Association also fears many contractors will not survive.

Chevron Right Icon 'There's every likelihood this could be a big problem in terms of the impact on potential home owners'

The liquidator doubts there are enough tangible assets to pay down the company's debt.

In which case, the directors are likely to be personally pursued.