The writing process was supported by Innovation Fund Denmark (EliteOva).

References

Abe , H and Hoshi , H 1997 . Bovine oviductal epithelial cells: their cell culture and applications in studies for reproductive biology . Cytotechnology 23 , 171 – 183 .

Abe , H and Hoshi , H 2003 . Evaluation of bovine embryos produced in high performance serum-free media . Journal of Reproduction and Development 49 , 193 – 202 .

Akst , J 2017 . New techniques detail embryos’ first hours and days . The Scientist 31 , 28 – 35 .

Albuz , FK , Sasseville , M , Lane , M , Armstrong , DT , Thompson , JG and Gilchrist , RB 2010 . Simulated physiological oocyte maturation (SPOM): a novel in vitro maturation system that substantially improves embryo yield and pregnancy outcomes . Human Reproduction 25 , 2999 – 3011 .

Alminana , C , Corbin , E , Tsikis , G , Alcantara-Neto , AS , Labas , V , Reynaud , K , Galio , L , Uzbekov , R , Garanina , AS , Druart , X and Mermillod , P 2017 . Oviduct extracellular vesicles protein content and their role during oviduct-embryo cross-talk . Reproduction 154 , 153 – 168 .

Alvarez-Gallardo , H , Kjelland , ME , Moreno , JF , Welsh , TH Jr. , Randel , RD , Lammoglia , MA , Perez-Martinez , M , Lara-Sagahon , AV , Esperon-Sumano , AE and Romo , S 2013 . Gamete therapeutics: recombinant protein adsorption by sperm for increasing fertility via artificial insemination . PLOS ONE 8 , 1 – 8 .

An , LY , Chaubal , SA , Liu , Y , Chen , Y , Nedambale , TL , Xu , J , Xue , F , Moreno , JF , Tao , S , Presicce , GA and Du , F 2017 . Significant heparin effect on bovine embryo development during sexed in vitro fertilization . Journal of Reproduction and Development 63 , 175 – 183 .

Baldassarre , H , Currin , L , Michalovic , L , Bellefleur , AM , Gutierrez , K , Mondadori , RG , Glanzner , WG , Schuermann , Y , Bohrer , RC , Dicks , N , Lopez , R , Grand , FX , Vigneault , C , Blondin , P , Gourdon , J and Bordignon , V 2018 . Interval of gonadotropin administration for in vitro embryo production from oocytes collected from Holstein calves between 2 and 6 months of age by repeated laparoscopy . Theriogenology 116 , 64 – 70 .

Baltz , JM 2013 . Connections between preimplantation embryo physiology and culture . Journal of Assisted Reproduction and Genetics 30 , 1001 – 1007 .

Bavister , BD 1995 . Culture of preimplantation embryos: facts and artifacts . Human Reproduction Update 1 , 91 – 148 .

Berglund , B 2008 . Genetic improvement of dairy cow reproductive performance . Reproduction in Domestic Animals 43 , 89 – 95 .

Bermejo-Alvarez , P , Lonergan , P , Rath , D , Gutierrez-Adan , A and Rizos , D 2010 a. Developmental kinetics and gene expression in male and female bovine embryos produced in vitro with sex-sorted spermatozoa . Reproduction, Fertility and Development 22 , 426 – 436 .

Bermejo-Alvarez , P , Rizos , D , Rath , D , Lonergan , P and Gutierrez-Adan , A 2010 b. Sex determines the expression level of one third of the actively expressed genes in bovine blastocysts . Proceedings of the National Academy of Sciences 107 , 3394 – 3399 .

Biggers , JD and Summers , MC 2008 . Choosing a culture medium: making informed choices . Fertility and Sterility 90 , 473 – 483 .

Blondin , P , Beaulieu , M , Fournier , V , Morin , N , Crawford , L , Madan , P and King , WA 2009 . Analysis of bovine sexed sperm for IVF from sorting to the embryo . Theriogenology 71 , 30 – 38 .

Bols , PE , Leroy , JLMR , Vanholder , T and Van Soom , A 2004 . A comparison of a mechanical sector and a linear array transducer for ultrasound-guided transvaginal oocyte retrieval (OPU) in the cow . Theriogenology 62 , 906 – 914 .

Bols , PE , Leroy , JLMR and Viana , JHM 2005 . Technical and biological aspects of ultrasound-guided transvaginal oocyte retrieval in the cow: an overview. Acta Scientiae Veterinariae , 103 – 108 .

Bruyere , P , Baudot , A , Guyader-Joly , C , Guerin , P , Louis , G and Buff , S 2012 . Improved cryopreservation of in vitro-produced bovine embryos using a chemically defined freezing medium . Theriogenology 78 , 1294 – 1302 .

Cavalieri , FLB , Morotti , F , Seneda , MM , Colombo , AHB , Andreazzi , MA , Emanuelli , IP and Rigolon , LP 2017 . Improvement of bovine in vitro embryo production by ovarian follicular wave synchronization prior to ovum pick-up . Theriogenology 117 , 57 – 60 .

Chaubal , SA , Ferre , LB , Molina , JA , Faber , DC , Bols , PE , Rezamand , P , Tian , X and Yang , X 2007 . Hormonal treatments for increasing the oocyte and embryo production in an OPU-IVP system . Theriogenology 67 , 719 – 728 .

Cognié , Y , Baril , G , Poulin , N and Mermillod , P 2003 . Current status of embryo technologies in sheep and goat . Theriogenology 59 , 171 – 188 .

da Silveira , JC , Andrade , GM , Del Collado , M , Sampaio , RV , Sangalli , JR , Silva , LA , Pinaffi , FVL , Jardim , IB , Cesar , MC , Nogueira , MFG , Cesar , ASM , Coutinho , LL , Pereira , RW , Perecin , F and Meirelles , FV 2017 . Supplementation with small-extracellular vesicles from ovarian follicular fluid during in vitro production modulates bovine embryo development . PLOS ONE 12 , 1 – 25 .

Daly , J , Zuchowicz , N , Nuñez Lendo , CI , Khosla , K , Lager , C , Henley , EM , Bischof , J , Kleinhans , FW , Lin , C , Peters , EC and Hagedorn , M 2018 . Successful cryopreservation of coral larvae using vitrification and laser warming . Scientific Reports 8 , 1 – 10 .

de Graaf , SP , Evans , G , Maxwell , WM , Cran , DG and O’Brien , JK 2007 . Birth of offspring of pre-determined sex after artificial insemination of frozen-thawed, sex-sorted and re-frozen-thawed ram spermatozoa . Theriogenology 67 , 391 – 398 .

de Loos , F , van Vliet , C , van Maurik , P and Kruip , TA 1989 . Morphology of immature bovine oocytes . Gamete Research 24 , 197 – 204 .

de Sousa , RV , da Silva Cardoso , CR , Butzke , G , Dode , MAN , Rumpf , R and Franco , MM 2017 . Biopsy of bovine embryos produced in vivo and in vitro does not affect pregnancy rates . Theriogenology 90 , 25 – 31 .

Di Pietro , C 2016 . Exosome-mediated communication in the ovarian follicle . Journal of Assisted Reproduction and Genetics 33 , 303 – 311 .

Donnay , I , Partridge , RJ and Leese , HJ 1999 . Can embryo metabolism be used for selecting bovine embryos before transfer? Reproduction Nutrition and Development 39 , 523 – 533 .

Druart , X , Cognie , J , Baril , G , Clement , F , Dacheux , JL and Gatti , JL 2009 . In vivo imaging of in situ motility of fresh and liquid stored ram spermatozoa in the ewe genital tract . Reproduction 138 , 45 – 53 .

Dunning , KR , Russell , DL and Robker , RL 2014 . Lipids and oocyte developmental competence: the role of fatty acids and β-oxidation . Reproduction 148 , R15 – R27 .

Ectors , FJ , Thonon , F , Delval , A , Fontes , RS , Touati , K , Beckers , JF and Ectors , F 1993 . Comparison between culture of bovine embryos in vitro versus development in rabbit oviducts and in vivo . Livestock Production Science 36 , 29 – 34 .

Eyestone , WH and First , NL 1989 . Co-culture of early cattle embryos to the blastocyst stage with oviducal tissue or in conditioned medium . Journal of Reproduction and Fertility 85 , 715 – 720 .

Farin , PW , Crosier , AE and Farin , CE 2001 . Influence of in vitro systems on embryo survival and fetal development in cattle . Theriogenology 55 , 151 – 170 .

Feres , LF , Siqueira , LGB , Palhao , MP , Dos Santos , LL , Brandao , FZ and Viana , JHM 2018 . Likelihood of pregnancy after the transfer of embryos derived from follicle aspiration and in vitro embryo production sessions with different relative efficiencies . Animal Reproduction Science 193 , 165 – 170 .

Fernandes , CAdC , Miyauchi , TM , Figueiredo , ACSd , Palhão , MP , Varago , FC , Nogueira , ESC , Neves , JP and Miyauchi , TA 2014 . Hormonal protocols for in vitro production of Zebu and taurine embryos . Pesquisa Agropecuária Brasileira 49 , 813 – 817 .

Fontanesi , L 2016 . Metabolomics and livestock genomics: insights into a phenotyping frontier and its applications in animal breeding . Animal Frontiers 6 , 73 – 79 .

Fulka , J Jr. , First , NL and Moor , RM 1998 . Nuclear and cytoplasmic determinants involved in the regulation of mammalian oocyte maturation . Molecular Human Reproduction 4 , 41 – 49 .

Gad , A , Hoelker , M , Besenfelder , U , Havlicek , V , Cinar , U , Rings , F , Held , E , Dufort , I , Sirard , MA , Schellander , K and Tesfaye , D 2012 . Molecular mechanisms and pathways involved in bovine embryonic genome activation and their regulation by alternative in vivo and in vitro culture conditions . Biology of Reproduction 87 , 1 – 13 .

Galli , C , Duchi , R , Crotti , G , Turini , P , Ponderato , N , Colleoni , S , Lagutina , I and Lazzari , G 2003 . Bovine embryo technologies . Theriogenology 59 , 599 – 616 .

Gandhi , AP , Lane , M , Gardner , DK and Krisher , RL 2000 . A single medium supports development of bovine embryos throughout maturation, fertilization and culture . Human Reproduction 15 , 395 – 401 .

Gardner , DK 2008 . Dissection of culture media for embryos: the most important and less important components and characteristics . Reproduction, Fertility and Development 20 , 9 – 18 .

Gardner , DK and Lane , M 2002 . Development of viable mammalian embryos in vitro: evolution of sequential media . In Principles of cloning (ed. Cibelli , J , Lanza , RP , Campbell , KHS and West , MD ), pp. 187 – 213 , Academic Press , San Diego, CA, USA .

Garner , DL 2001 . Sex-sorting mammalian sperm: concept to application in animals . Journal of Andrology 22 , 519 – 526 .

Garner , DL , Evans , KM and Seidel , GE Jr. 2013 . Sex-sorting sperm using flow cytometry/cell sorting . Methods in Molecular Biology 927 , 279 – 295 .

Goddard , ME , Hayes , BJ and Meuwissen , THE 2010 . Genomic selection in livestock populations . Genetics Research 92 , 413 – 421 .

Gonzalez-Marin , C , Lenz , RW , Gilligan , TB , Evans , KM , Gongora , CE , Moreno , JF and Vishwanath , R 2017 . SexedULTRA™, a new method of processing sex sorted bovine sperm improves post-thaw sperm quality and in vitro fertility . Reproduction, Fertility and Development 29 , 204 – 204 .

Gopichandran , N and Leese , HJ 2006 . The effect of paracrine/autocrine interactions on the in vitro culture of bovine preimplantation embryos . Reproduction 131 , 269 – 277 .

Gordon , I 2003 . In vitro fertilization . In Laboratory production of cattle embryos (ed. Gordon , I ), pp. 176 – 219 , CABI Publishing , Oxon, UK .

Goto , K , Kajihara , Y , Kosaka , S , Koba , M , Nakanishi , Y and Ogawa , K 1988 . Pregnancies after co-culture of cumulus cells with bovine embryos derived from in-vitro fertilization of in-vitro matured follicular oocytes . Journal of Reproduction and Fertility 83 , 753 – 758 .

Gross , N , Kropp , J and Khatib , H 2017 . MicroRNA signaling in embryo development . Biology (Basel) 6 , 1 – 22 .

Guimarães , ALS , Pereira , SA , Leme , LO and Dode , MAN 2015 . Evaluation of the simulated physiological oocyte maturation system for improving bovine in vitro embryo production . Theriogenology 83 , 52 – 57 .

Hansen , PJ 2006 . Realizing the promise of IVF in cattle – an overview . Theriogenology 65 , 119 – 125 .

Hasler , JF 1998 . The current status of oocyte recovery, in vitro embryo production, and embryo transfer in domestic animals, with an emphasis on the Bovine . Journal of Animal Science 76 , 52 – 74 .

Holm , P , Booth , PJ , Schmidt , MH , Greve , T and Callesen , H 1999 . High bovine blastocyst development in a static in vitro production system using SOFaa medium supplemented with sodium citrate and myo-inositol with or without serum-proteins . Theriogenology 52 , 683 – 700 .

Hung , WT , Hong , X , Christenson , LK and McGinnis , LK 2015 . Extracellular vesicles from bovine follicular fluid support cumulus expansion . Biology of Reproduction 93 , 1 – 9 .

Hyttel , P , Fair , T , Callesen , H and Greve , T 1997 . Oocyte growth, capacitation and final maturation in cattle . Theriogenology 47 , 23 – 32 .

Hyttel , P , Xu , KP , Smith , S and Greve , T 1986 . Ultrastructure of in-vitro oocyte maturation in cattle . Journal of Reproduction and Fertility 78 , 615 – 625 .

Johnson , LA 1995 . Sex preselection by flow cytometric separation of X and Y chromosome-bearing sperm based on DNA difference: a review . Reproduction, Fertility and Development 7 , 893 – 903 .

Kasinathan , P , Wei , H , Xiang , T , Molina , JA , Metzger , J , Broek , D , Kasinathan , S , Faber , DC and Allan , MF 2015 . Acceleration of genetic gain in cattle by reduction of generation interval . Scientific Reports 5 , 1 – 4 .

Kelly , E and Cho , T 2014 . Incubators old and new . In Culture media, solutions, and systems in human ART (ed. Quinn , P ), pp. 258 – 269 , Cambridge University Press , Cambridge, UK .

Khosla , K , Wang , Y , Hagedorn , M , Qin , Z and Bischof , J 2017 . Gold Nanorod Induced Warming of Embryos from the Cryogenic State Enhances Viability . ACS Nano 11 , 7869 – 7878 .

Killian , G 2011 . Physiology and endocrinology symposium: evidence that oviduct secretions influence sperm function: a retrospective view for livestock . Journal of Animal Science 89 , 1315 – 1322 .

Kovacs , P 2014 . Embryo selection: the role of time-lapse monitoring . Reproductive Biology and Endocrinology 12 , 1 – 11 .

Krisher , RL 2004 . The effect of oocyte quality on development . Journal of Animal Science 82 , E14 – E23 .

Kropp , J and Khatib , H 2015 . mRNA fragments in in vitro culture media are associated with bovine preimplantation embryonic development . Frontiers in Genetics 6 , 1 – 7 .

Lamy , J , Corbin , E , Blache , MC , Garanina , AS , Uzbekov , R , Mermillod , P and Saint-Dizier , M 2017 . Steroid hormones regulate sperm-oviduct interactions in the bovine . Reproduction 154 , 497 – 508 .

Lamy , J , Nogues , P , Combes-Soia , L , Tsikis , G , Labas , V , Mermillod , P , Druart , X and Saint-Dizier , M 2018 . Identification by proteomics of oviductal sperm-interacting proteins . Reproduction 155 , 457 – 466 .

Lane , M , Gardner , DK , Hasler , MJ and Hasler , JF 2003 . Use of G1. 2/G2. 2 media for commercial bovine embryo culture: equivalent development and pregnancy rates compared to co-culture . Theriogenology 60 , 407 – 419 .

Lazzari , G , Colleoni , S , Lagutina , I , Crotti , G , Turini , P , Tessaro , I , Brunetti , D , Duchi , R and Galli , C 2010 . Short-term and long-term effects of embryo culture in the surrogate sheep oviduct versus in vitro culture for different domestic species . Theriogenology 73 , 748 – 757 .

Lazzari , G , Wrenzycki , C , Herrmann , D , Duchi , R , Kruip , T , Niemann , H and Galli , C 2002 . Cellular and molecular deviations in bovine in vitro-produced embryos are related to the large offspring syndrome . Biology of Reproduction 67 , 767 – 775 .

Leibfried-Rutledge , ML , Critser , ES , Eyestone , WH , Northey , DL and First , NL 1987 . Development potential of bovine oocytes matured in vitro or in vivo . Biology of Reproduction 36 , 376 – 383 .

Li , S and Winuthayanon , W 2017 . Oviduct: roles in fertilization and early embryo development . Journal of Endocrinology 232 , R1 – R26 .

Lim , JM , Mei , Y , Chen , B , Godke , RA and Hansel , W 1999 . Development of bovine IVF oocytes cultured in medium supplemented with a nitric oxide scavenger or inhibitor in a co-culture system . Theriogenology 51 , 941 – 949 .

Liu , Z and Foote , RH 1995 . Development of bovine embryos in KSOM with added superoxide dismutase and taurine and with five and twenty percent O 2 . Biology of Reproduction 53 , 786 – 790 .

Liu , X , Hu , T , Sun , W , Hao , H , Liu , Y , Zhao , X , Zhu , H and Du , W 2015 . Comparison of the developmental competence and quality of bovine embryos obtained by in vitro fertilization with sex-sorted and unsorted semen from seven bulls . Livestock Science 181 , 263 – 270 .

Lonergan , P , Rizos , D , Gutierrez-Adan , A , Fair , T and Boland , MP 2003 . Effect of culture environment on embryo quality and gene expression – experience from animal studies . Reproductive BioMedicine Online 7 , 657 – 663 .

Lonergan , P , Rizos , D , Ward , F and Boland , MP 2001 . Factors influencing oocyte and embryo quality in cattle . Reproduction Nutrition Development 41 , 427 – 437 .

Lopera-Vasquez , R , Hamdi , M , Maillo , V , Gutierrez-Adan , A , Bermejo-Alvarez , P , Ramírez , MÁ , Yáñez-Mó , M and Rizos , D 2017 . Effect of bovine oviductal extracellular vesicles on embryo development and quality in vitro . Reproduction 153 , 461 – 470 .

Lu , KH , Cran , DG and Seidel , GE Jr. 1999 . In vitro fertilization with flow-cytometrically-sorted bovine sperm . Theriogenology 52 , 1393 – 1405 .

Lu , KH and Polge , C 1992 . A summary of two-year’s results in large scale in vitro bovine embryo production. In Proceedings of the 12th International Congress on Animal Reproduction, 23–27 August 1992, the Hague, Netherlands, pp. 1315 – 1317 .

Lu , KH and Seidel , GE Jr. 2004 . Effects of heparin and sperm concentration on cleavage and blastocyst development rates of bovine oocytes inseminated with flow cytometrically-sorted sperm . Theriogenology 62 , 819 – 830 .

Macklon , NS , Pieters , MH , Hassan , MA , Jeucken , PH , Eijkemans , MJ and Fauser , BC 2002 . A prospective randomized comparison of sequential versus monoculture systems for in-vitro human blastocyst development . Human Reproduction 17 , 2700 – 2705 .

Massip , A and Leibo , SP 2002 . Factors influencing cryopreservation of domestic animal embryos . In Assessment of mammalian embryo quality (ed. Soom , A Van and Boerjan , M ), pp. 121 – 138 , Springer , Dordrecht, Netherlands .

McEvoy , TG , Alink , FM , Moreira , VC , Watt , RG and Powell , KA 2006 . Embryo technologies and animal health – consequences for the animal following ovum pick-up, in vitro embryo production and somatic cell nuclear transfer . Theriogenology 65 , 926 – 942 .

Mermillod , P , Oussaid , B and Cognie , Y 1999 . Aspects of follicular and oocyte maturation that affect the developmental potential of embryos . Journal of Reproduction and Fertility 54 , 449 – 460 .

Mermillod , P , Vansteenbrugge , A , Wils , C , Mourmeaux , JL , Massip , A and Dessy , F 1993 . Characterization of the embryotrophic activity of exogenous protein-free oviduct-conditioned medium used in culture of cattle embryos . Biology of Reproduction 49 , 582 – 587 .

Mermillod , P Tomanek , M Marchal , R Meijer , L 2000 . High developmental competence of cattle oocytes maintained at the germinal vesicle stage for 24 hours in culture by specific inhibition of MPF kinase activity . Molecular Reproduction and Development 55 , 89 – 95 .

Merton , JS , de Roos , APW , Mullaart , E , de Ruigh , L , Kaal , L , Vos , PLAM and Dieleman , SJ 2003 . Factors affecting oocyte quality and quantity in commercial application of embryo technologies in the cattle breeding industry . Theriogenology 59 , 651 – 674 .

Mondéjar , I , Martínez-Martínez , I , Avilés , M and Coy , P 2013 . Identification of potential oviductal factors responsible for zona pellucida hardening and monospermy during fertilization in mammals . Biology of Reproduction 89 , 1 – 8 .

Monteiro , FM , Ferreira , MM , Potiens , JR , Eberhardt , BG , Trinca , LA and Barros , CM 2010 . Influence of superovulatory protocols on in vitro production of Nellore (Bos indicus) embryos . Reproduction in Domestic Animals 45 , 860 – 864 .

Moore , K , Rodriguez-Sallaberry , CJ , Kramer , JM , Johnson , S , Wroclawska , E , Goicoa , S and Niasari-Naslaji , A 2007 . In vitro production of bovine embryos in medium supplemented with a serum replacer: effects on blastocyst development, cryotolerance and survival to term . Theriogenology 68 , 1316 – 1325 .

Morotti , F , Sanches , BV , Pontes , JH , Basso , AC , Siqueira , ER , Lisboa , LA and Seneda , MM 2014 . Pregnancy rate and birth rate of calves from a large-scale IVF program using reverse-sorted semen in Bos indicus, Bos indicus-taurus, and Bos taurus cattle . Theriogenology 81 , 696 – 701 .

Munevver , S , Findikli , N and Bahceci , M 2017 . New Horizons/Developments in time-lapse morphokinetic analysis of mammalian embryos . In Human reproduction: updates and new horizons (ed. Schatten , H ), pp. 313 – 338 , John Wiley & Sons, Inc. , Hoboken, NJ, USA .

Nedambale , TL , Dinnyes , A , Groen , W , Dobrinsky , JR , Tian , XC and Yang , X 2004 . Comparison on in vitro fertilized bovine embryos cultured in KSOM or SOF and cryopreserved by slow freezing or vitrification . Theriogenology 62 , 437 – 449 .

Nivet , AL , Bunel , A , Labrecque , R , Belanger , J , Vigneault , C , Blondin , P and Sirard , MA 2012 . FSH withdrawal improves developmental competence of oocytes in the bovine model . Reproduction 143 , 165 – 171 .

Olson , SE and Seidel , GE Jr. 2000 . Reduced oxygen tension and EDTA improve bovine zygote development in a chemically defined medium . Journal of Animal Science 78 , 152 – 157 .

Orsi , NM and Reischl , JB 2007 . Mammalian embryo co-culture: trials and tribulations of a misunderstood method . Theriogenology 67 , 441 – 458 .

Parrish , JJ , Susko-Parrish , JL , Leibfried-Rutledge , ML , Critser , ES , Eyestone , WH and First , NL 1986 . Bovine in vitro fertilization with frozen-thawed semen . Theriogenology 25 , 591 – 600 .

Pieterse , MC , Kappen , KA , Kruip , TAM and Taverne , MAM 1988 . Aspiration of bovine oocytes during transvaginal ultrasound scanning of the ovaries . Theriogenology 30 , 751 – 762 .

Ponsart , C , Le Bourhis , D , Knijn , H , Fritz , S , Guyader-Joly , C , Otter , T , Lacaze , S , Charreaux , F , Schibler , L , Dupassieux , D and Mullaart , E 2013 . Reproductive technologies and genomic selection in dairy cattle . Reproduction, Fertility and Development 26 , 12 – 21 .

Rizos , D , Clemente , M , Bermejo-Alvarez , P , De La Fuente , J , Lonergan , P and Gutiérrez-Adán , A 2008 . Consequences of in vitro culture conditions on embryo development and quality . Reproduction in Domestic Animals 43 , 44 – 50 .

Rizos , D , Gutierrez-Adan , A , Perez-Garnelo , S , De La Fuente , J , Boland , MP and Lonergan , P 2003 . Bovine embryo culture in the presence or absence of serum: implications for blastocyst development, cryotolerance, and messenger RNA expression . Biology of Reproduction 68 , 236 – 243 .

Rizos , D , Ramirez , MA , Pintado , B , Lonergan , P and Gutierrez-Adan , A 2010 . Culture of bovine embryos in intermediate host oviducts with emphasis on the isolated mouse oviduct . Theriogenology 73 , 777 – 785 .

Rizos , D , Ward , F , Duffy , P , Boland , MP and Lonergan , P 2002 . Consequences of bovine oocyte maturation, fertilization or early embryo development in vitro versus in vivo: implications for blastocyst yield and blastocyst quality . Molecular Reproduction and Development 61 , 234 – 248 .

Rødgaard , T , Heegaard , PMH and Callesen , H 2015 . Non-invasive assessment of in-vitro embryo quality to improve transfer success . Reproductive BioMedicine Online 31 , 585 – 592 .

Rodgers , RJ and Irving-Rodgers , HF 2010 . Formation of the ovarian follicular antrum and follicular fluid . Biology of Reproduction 82 , 1021 – 1029 .

Rosenkrans , CF and First , NL 1994 . Effect of free amino acids and vitamins on cleavage and developmental rate of bovine zygotes in vitro . Journal of Animal Science 72 , 434 – 437 .

Saeed-Zidane , M , Linden , L , Salilew-Wondim , D , Held , E , Neuhoff , C , Tholen , E , Hoelker , M , Schellander , K and Tesfaye , D 2017 . Cellular and exosome mediated molecular defense mechanism in bovine granulosa cells exposed to oxidative stress . PLOS ONE 12 , 1 – 24 .

Santonocito , M , Vento , M , Guglielmino , MR , Battaglia , R , Wahlgren , J , Ragusa , M , Barbagallo , D , Borzi , P , Rizzari , S , Maugeri , M , Scollo , P , Tatone , C , Valadi , H , Purrello , M and Di Pietro , C 2014 . Molecular characterization of exosomes and their microRNA cargo in human follicular fluid: bioinformatic analysis reveals that exosomal microRNAs control pathways involved in follicular maturation . Fertility and Sterility 102 , 1751 – 1761 .

Schmaltz-Panneau , B , Locatelli , Y , Uzbekova , S , Perreau , C and Mermillod , P 2015 . Bovine oviduct epithelial cells dedifferentiate partly in culture, while maintaining their ability to improve early embryo development rate and quality . Reproduction in Domestic Animals 50 , 719 – 729 .

Sendag , S , Cetin , Y , Alan , M , Hadeler , K-G and Niemann , H 2008 . Effects of eCG and FSH on ovarian response, recovery rate and number and quality of oocytes obtained by ovum pick-up in Holstein cows . Animal Reproduction Science 106 , 208 – 214 .

Silva-Santos , KC , Santos , GM , Koetz Junior , C , Morotti , F , Siloto , LS , Marcantonio , TN , Urbano , MR , Oliveira , RL , Lima , DC and Seneda , MM 2014 . Antral follicle populations and embryo production – in vitro and in vivo – of Bos indicus-taurus donors from weaning to yearling ages . Reproduction in Domestic Animals 49 , 228 – 232 .

Sirard , MA 2001 . Resumption of meiosis: mechanism involved in meiotic progression and its relation with developmental competence . Theriogenology 55 , 1241 – 1254 .

Sirard , MA 2018 . 40 years of bovine IVF in the new genomic selection context . Reproduction 156 , R1 – R7 .

Sirard , MA and Blondin , P 1996 . Oocyte maturation and IVF in cattle . Animal Reproduction Science 42 , 417 – 426 .

Sirard , MA , Richard , F , Blondin , P and Robert , C 2006 . Contribution of the oocyte to embryo quality . Theriogenology 65 , 126 – 136 .

Stroebech , L , Mazzoni , G , Pedersen , HS , Freude , KK , Kadarmideen , HN , Callesen , H and Hyttel , P 2015 . In vitro production of bovine embryos: revisiting oocyte development and application of systems biology . Animal Reproduction 12 , 465 – 472 .

Sugimura , S , Akai , T and Imai , K 2017 . Selection of viable in vitro-fertilized bovine embryos using time-lapse monitoring in microwell culture dishes . Journal of Reproduction and Development 63 , 353 – 357 .

Suh , TK , Schenk , JL and Seidel , GE Jr. 2005 . High pressure flow cytometric sorting damages sperm . Theriogenology 64 , 1035 – 1048 .

Swain , JE 2010 . Optimizing the culture environment in the IVF laboratory: impact of pH and buffer capacity on gamete and embryo quality . Reproductive BioMedicine Online 21 , 6 – 16 .

Tanghe , S , Van Soom , A , Talebkhan Garoussi , M , Mintiens , K and de Kruif , A 2000 . Sperm-egg ratios above 5000: 1 do not improve in vitro fertilization rates in the bovine . Journal of Reproduction and Fertility 25 , 91 .

Tervit , HR , Whittingham , DG and Rowson , LE 1972 . Successful culture in vitro of sheep and cattle ova . Journal of Reproduction and Fertility 30 , 493 – 497 .

Tesfaye , D , Ghanem , N , Carter , F , Fair , T , Sirard , M-A , Hoelker , M , Schellander , K and Lonergan , P 2009 . Gene expression profile of cumulus cells derived from cumulusoocyte complexes matured either in vivo or in vitro . Reproduction, Fertility and Development 21 , 451 – 461 .

Thompson , JG 2000 . In vitro culture and embryo metabolism of cattle and sheep embryos – a decade of achievement . Animal Reproduction Science 60–61 , 263 – 275 .

Thompson , JG , Allen , NW , McGowan , LT , Bell , AC , Lambert , MG and Tervit , HR 1998 . Effect of delayed supplementation of fetal calf serum to culture medium on bovine embryo development in vitro and following transfer . Theriogenology 49 , 1239 – 1249 .

Thompson , JG and Peterson , AJ 2000 . Bovine embryo culture in vitro: new developments and post-transfer consequences . Human Reproduction 15 , 59 – 67 .

Vajta , G 2000 . Vitrification of the oocytes and embryos of domestic animals . Animal Reproduction Science 60–61 , 357 – 364 .

Van Soom , A , Mateusen , B , Leroy , J and de Kruif , A 2003 . Assessment of mammalian embryo quality: what can we learn from embryo morphology? Reproductive BioMedicine Online 7 , 664 – 670 .

Van Soom , A , Van Vlaenderen , I , Mahmoudzadeh , A and de Kruif , A 1991 . Bull specific effect on in vitro penetration and fertilization of bovine oocytes using various levels of heparin . Assisted Reproductive Technology/Andrology 2 , 105 – 106 .

Vieira , LM , Rodrigues , CA , Castro Netto , A , Guerreiro , BM , Silveira , CRA , Freitas , BG , Bragança , LGM , Marques , KNG , Sá Filho , MF , Bó , GA , Mapletoft , RJ and Baruselli , PS 2016 . Efficacy of a single intramuscular injection of porcine FSH in hyaluronan prior to ovum pick-up in Holstein cattle . Theriogenology 85 , 877 – 886 .

Ward , F , Enright , B , Rizos , D , Boland , M and Lonergan , P 2002 . Optimization of in vitro bovine embryo production: effect of duration of maturation, length of gamete co-incubation, sperm concentration and sire . Theriogenology 57 , 2105 – 2117 .

Ward , FA , Lonergan , P , Enright , BP and Boland , MP 2000 . Factors affecting recovery and quality of oocytes for bovine embryo production in vitro using ovum pick-up technology . Theriogenology 54 , 433 – 446 .

Watanabe , Y , Souza , HA , Mingoti , R , Ferreira , R , Oliveira Santana Batista , E , Dayan , A , Watanabe , O , Meirelles , F , Nogueira , M , Ferraz , J and Baruselli , P 2017 . Number of oocytes retrieved per donor during OPU and its relationship with in vitro embryo production and field fertility following embryo transfer . Animal Reproduction 14 , 635 – 644 .

Watson , AJ 2007 . Oocyte cytoplasmic maturation: a key mediator of oocyte and embryo developmental competence . Journal of Animal Science 85 , E1 – E3 .

Webb , R , Garnsworthy , P , Gong , J-G and Armstrong , D 2004 . Control of follicular growth: local interactions and nutritional influences . Journal of Animal Science 82 , E63 – E74 .

Welch , GR and Johnson , LA 1999 . Sex preselection: laboratory validation of the sperm sex ratio of flow sorted X- and Y-sperm by sort reanalysis for DNA . Theriogenology 52 , 1343 – 1352 .

Wheeler , MB and Rubessa , M 2017 . Integration of microfluidics in animal in vitro embryo production . Molecular Human Reproduction 23 , 248 – 256 .

Wrenzycki , C 2016 . In vitro culture systems: how far are we from optimal conditions? Animal Reproduction 13 , 279 – 282 .

Xu , J , Chaubal , SA and Du , F 2009 . Optimizing IVF with sexed sperm in cattle . Theriogenology 71 , 39 – 47 .

Xu , J , Guo , Z , Su , L , Nedambale , TL , Zhang , J , Schenk , J , Moreno , JF , Dinnyes , A , Ji , W , Tian , XC , Yang , X and Du , F 2006 . Developmental potential of vitrified holstein cattle embryos fertilized in vitro with sex-sorted sperm . Journal of Dairy Science 89 , 2510 – 2518 .

Yum , S-Y , Youn , K-Y , Choi , W-J and Jang , G 2018 . Development of genome engineering technologies in cattle: from random to specific . Journal of Animal Science and Biotechnology 9 , 1 – 9 .

Zhang , M , Lu , KH and Seidel , GE Jr. 2003 . Development of bovine embryos after in vitro fertilization of oocytes with flow cytometrically sorted, stained and unsorted sperm from different bulls . Theriogenology 60 , 1657 – 1663 .