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One person is dead after a collision between at least four vehicles in southeast Calgary Wednesday afternoon. One of the drivers involved has epilepsy and may have had a seizure at the time, according to his employer at Trevi Pools and Spa.

Police said officers were called to the area of 128 Avenue and 46 Street S.E. at around 12:30 p.m.

WATCH: Footage from Global1 chopper of a fatal vehicle collision in southeast Calgary.

0:55 Calgary police on scene of a fatal vehicle collision Calgary police on scene of a fatal vehicle collision

“A 39-year-old male was operating a black pickup truck through the intersection at 130 Avenue and left that location at a fairly high rate of speed,” Sgt. Colin Foster said.

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“The vehicle then struck a car that was coming out of the Canadian Tire superstore,” he said. “As a result of that collision, the driver of the red [vehicle] was pronounced deceased at the scene.”

One of the vehicles involved in a fatal crash in southeast Calgary Wednesday afternoon is seen being towed away from the scene. Global News

Co-owner of Trevi Pools and Spa Paul Tallon said the driver of the pickup truck was undergoing tests in hospital Wednesday afternoon.

The driver wasn’t working at the time of the collision, but was driving his personal truck, which has company decals on it.

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“Today’s accident was an unfortunate and unexpected tragedy,” Tallon said.

“Trevi is doing everything it can to help assist police with the investigation of today’s unfortunate event.

“The entire team at Trevi extends our deepest sympathies to the victims as well as the families and friends affected by this tragic loss.”

WATCH: Rebecca Mayhew-Lear describes what she saw during a fatal vehicle collision in southeast Calgary.

1:37 Witness describes fatal vehicle collision in southeast Calgary Witness describes fatal vehicle collision in southeast Calgary

A female passenger of the red car was taken to hospital in critical condition.

Witness Rebecca Mayhew-Lear said she was trying to get to Deerfoot Trail when she saw the driver of the truck coming through the nearby construction zone, with a pylon stuck underneath his truck.

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“He proceeded on the grass coming up this way and the little red sedan was sitting there waiting to turn and he t-boned them, pushed them into the parking lot,” she said.

WATCH: A medical crisis may have been involved in a deadly four vehicle crash. Mia Sosiak reports.

2:00 Surviving driver in deadly southeast Calgary crash may have suffered epileptic seizure Surviving driver in deadly southeast Calgary crash may have suffered epileptic seizure

Two other parked vehicles were damaged in the crash.

Collision investigators were on scene Wednesday afternoon and several roads appeared to be blocked off as officers determined what led to the crash.

Foster said it was too early to determine if alcohol or drugs were a factor.

Police declined to provide further details to Global News Wednesday, but said there is no indication the crash was a result of road rage.

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On Thursday, police confirmed they are looking at the pickup driver’s pre-existing medical condition as a possible factor in the crash.

Watch below from Aug. 3: Calgary police have confirmed they are looking at a pre-existing medical condition as a possible cause to a fatal crash in a southeast shopping area. Jill Croteau reports.

1:12 Calgary police investigating pre-existing medical condition in fatal crash Calgary police investigating pre-existing medical condition in fatal crash

Click here to read the Alberta government’s guidelines on driving and medical conditions

With files from Jill Croteau