The Food and Drug Administration said it would bar the sale of fruit- and mint-flavored e-cigarette cartridges—dealing a severe blow to one of the industry’s biggest players and placing more pressure on manufacturers already facing a May 12 deadline for federal review of their products.

The FDA said on Thursday it would block the sale of fruit and mint flavors in cartridge-based e-cigarettes popular with young people, but wouldn’t apply the restriction to tank vaping systems commonly found at vape shops.

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