Gary Sanchez and Austin Romine will have their suspension appeal hearings Friday, but MLB’s decision likely won’t be rendered until Tuesday or Wednesday because the league’s offices are closed for Labor Day weekend.

Such a timetable means the Yankees won’t lose Sanchez and Romine for any of the three remaining games against the Red Sox this weekend. The decisions could impact their availability for a three-game series against the Orioles that starts Monday in Baltimore, but manager Joe Girardi doesn’t expect to lose Sanchez and Romine at the same time.

“What I understand is that both players won’t be suspended at the same time,’’ Girardi said before the Yankees’ 6-2 win on Thursday night.

Sanchez was suspended for four games and Romine two for their roles in an Aug. 24 brawl with the Tigers.

Players will be represented by a Players Association representative and the hearings will be held in the morning or early afternoon so Sanchez and Romine can attend if they wish. Romine, on Thursday, wasn’t sure if he would sit in.

Journeyman catcher Erik Kratz, acquired from the Indians on Thursday, will be with the Yankees on Friday when big-league rosters are expanded from 25. Kratz, 37, hit .270 with 13 homers and 37 RBIs in 86 games with Triple-A Columbus this year.

Kratz has played with the Pirates, Phillies, Blue Jays, Royals and Astros and is a .200 big-league hitter.

Girardi had Aroldis Chapman throwing in the seventh inning but sent David Robertson back for a second inning of work in the eighth. Then with a five-run lead in the ninth, Dellin Betances surfaced from the bullpen. And when Betances ran into turbulence, Girardi got Tommy Kahnle up.

Because Chapman hasn’t appeared in a game since last Friday and underwent an MRI exam on his left elbow Sunday, Girardi was asked if his former closer was healthy and he said he was fine.

Matt Holliday will rejoin the Yankees on Friday night.

The veteran DH has been on the DL since Aug. 5 with a left lumbar strain and hit .229 (8-for-35) without a homer and five RBIs in 10 combined minor league rehab games.

“It would be another big bat if we could get that going,’’ Girardi said. “He was a guy who was instrumental in our success in the first half.’’

As for Clint Frazier, Girardi said the rookie outfielder will not accompany the club on the upcoming road trip so that he can start a rehab assignment next week.

Frazier, who has been out since Aug. 9 with a strained left oblique muscle, took 24 swings in the indoor batting cage Thursday and is looking forward to hitting on the field Friday.

“I feel like nothing ever happened,’’ Frazier said. “I am not babying anything.’’

With the rosters expanding Friday, utility player Tyler Wade, a possible pinch-running candidate if the Yankees make the postseason, likely will be among the call-ups. The Yankees will choose from Triple-A Scranton/Wilkes-Barre pitchers Jordan Montgomery, Caleb Smith, Domingo German, Bryan Mitchell, Ben Heller and Jonathan Holder, all of whom are on the 40-man roster. Chance Adams, who is 11-4 with a 2.63 ERA in 20 games at Triple-A, isn’t on the 40-man roster.

In addition to Wade, position-player candidates are first baseman/outfielder Tyler Austin and third baseman Miguel Andujar.

All are on the 40-man roster.

Some thought might be given to not stripping Scranton/Wilkes-Barre, which will play in the International League playoffs, but the Yankees’ philosophy always has been if a player can help at the big-league level he will be called up.