(CNN) Celebrities including Amy Schumer and Chelsea Handler have launched an Instagram campaign targeted at Ivanka Trump, urging the US President's daughter to act on the administration's family-separation policy and calling for the resignation of Homeland Security Secretary Kirstjen Nielsen.

Comedian and television host Chelsea Handler is among those taking part in the "Dear Ivanka" Instragram campaign.

As part of the campaign, well-known figures followed by Ivanka Trump on Instagram -- including not just Schumer and Handler, but also American fashion entrepreneur Sophie Amoruso and British model Cara Delevingne -- have been posting messages detailing the alleged abuses of children under controversial family separations at the US-Mexico border in an effort to flood her feed.

The coordinated messages begin: "Dear Ivanka, you follow me on social media. You said family separation was a 'low point' for you. The low point is for the separated families. You spoke in past tense. This crisis is ongoing."

The White House did not respond to a request for comment.

@ivankatrump A post shared by @ amyschumer on Aug 6, 2018 at 8:43pm PDT

The campaign began after Trump broke her silence on family separations on Thursday, saying during an Axios News Shaper conversation that it "was a low point" of her time in the White House.

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