Texas Sen. Ted Cruz Rafael (Ted) Edward CruzCrenshaw looms large as Democrats look to flip Texas House seat SCOTUS confirmation in the last month of a close election? Ugly The Hill's Morning Report - Sponsored by Facebook - Trump previews SCOTUS nominee as 'totally brilliant' MORE (R) joked at a campaign rally that his opponent in the state's Senate race, Rep. Beto O'Rourke Beto O'RourkeJimmy Carter says his son smoked pot with Willie Nelson on White House roof O'Rourke endorses Kennedy for Senate: 'A champion for the values we're most proud of' 2020 Democrats do convention Zoom call MORE (D), could join 2016 Democratic nominee Hillary Clinton Hillary Diane Rodham ClintonBloomberg rolls out M ad buy to boost Biden in Florida Hillicon Valley: Productivity, fatigue, cybersecurity emerge as top concerns amid pandemic | Facebook critics launch alternative oversight board | Google to temporarily bar election ads after polls close Trump pledges to make Juneteenth a federal holiday, designate KKK a terrorist group in pitch to Black voters MORE in a "double-occupancy" prison cell.

The senator responded with the jab at Clinton to a rally audience member's call to "lock him up!", reportedly referring to O'Rourke, according to multiple reports.

"Well, you know, there's a double-occupancy cell with Hillary Clinton," Cruz said at a rally in Georgetown, Texas, north of Austin, alongside fellow Sen. John Cornyn John CornynHillicon Valley: Productivity, fatigue, cybersecurity emerge as top concerns amid pandemic | Facebook critics launch alternative oversight board | Google to temporarily bar election ads after polls close Lawmakers introduce legislation to boost cybersecurity of local governments, small businesses On The Trail: Making sense of this week's polling tsunami MORE (R-Texas). He then added: "Y'all are gonna get me in trouble with that."

As @TedCruz criticizes @BetoORourke in Georgetown, someone yells, "Lock him up!" Cruz: "Well, you know, there's a double-occupancy cell with Hillary Clinton." After big applause, Cruz adds, "Y'all are gonna get me in trouble with that." #txsen — Patrick Svitek (@PatrickSvitek) October 23, 2018

Attendees of rallies for President Trump Donald John TrumpFederal prosecutor speaks out, says Barr 'has brought shame' on Justice Dept. Former Pence aide: White House staffers discussed Trump refusing to leave office Progressive group buys domain name of Trump's No. 1 Supreme Court pick MORE used the chant "lock her up!" throughout 2016 and well into Trump's presidency to refer to Clinton and the FBI investigation into her use of a private email server at the State Department. The investigation faulted the former secretary for carelessness but declined to pursue charges against her.

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More recently, the chant was used to refer to Sen. Dianne Feinstein Dianne Emiel FeinsteinTrump plans to pick Amy Coney Barrett to replace Ginsburg on court Trump faces tricky choice on Supreme Court pick The Hill's Morning Report - Sponsored by Facebook - Trump previews SCOTUS nominee as 'totally brilliant' MORE (D-Calif.) during a Trump rally in Iowa earlier this month after the president mentioned the senator by name.

O'Rourke and Cruz are locked in a tight race for Cruz's Senate seat, with most polls showing the Texas senator leading by single digits. A RealClearPolitics average of polls shows Cruz leading by an average of 7 percentage points.

O'Rourke's success in the deep-red state has inspired a major cash flow from Democrats around the country, with his campaign reporting a record $38 million in fundraising in the 3rd quarter of 2018.