Police officers ended up in a shootout with two criminals after moving in on a robbery of a convenience store in Baltimore, Maryland.

Several CCTV cameras captured the dramatic moment when police and robbers opened fire on each other in the 7-11 store just after 1am on Tuesday.

Police are now offering a $24,000 reward for any information of the armed robbers who both fled the scene.

Shootout: CCTV cameras captured the dramatic moment when police and robbers opened fire in a 7-11 store in downtown Baltimore

Video shows two masked men attempting to rob the convenience store, forcing the store clerk to stand with their hands behind the counter.

Officers arrived at the scene and as they opened the door to confront the two men, the robbers opened fire.

'This is a situation that is absolutely disturbing,' Baltimore police media relations Chief T.J. Smith told WBALTV.

'They didn't hesitate to pull a gun out and pull the trigger on uniformed Baltimore City police officers they knew were going to be confronting them.'

Police returned fire, but neither officers nor the shop clerks were injured in the shoot out.

Fire: As police entered the shop, the robbers started shooting and officers fired back

Robbery: The two masked men walk into the 7-11 shop in downtown Baltimore and point a gun at the store clerk behind the counter

Manhunt: The two robbers were able to flee the scene and police are now offering a $24,000 reward for information

The two robbers were able to flee the scene, but is it not known if they suffered any injuries and police are checking hospitals for recent patients with gunshot wounds.

The same 7-11 was robbed three times last year, and police are urgently appealing for any information regarding the two suspects.

"If you look at this video and the way they handled themselves during this robbery, it certainly isn't their first time at the rodeo,' Mr Smith added.

'These don't look like inexperienced criminals, they look like hardened criminals.

'They look like people who wouldn't care if they killed someone last night. Fortunately, they didn't.'