Anne Hubbard has not lost her job, house or savings, and she and her husband have always been conservative with money.

But a few months ago, Ms. Hubbard, a graphic designer in Cambridge, Mass., began having panic attacks over the economy, struggling to breathe and seeing vivid visions of “losing everything,” she said.

She “could not stop reading every single economic report,” was so “sick to my stomach I lost 12 pounds” and “was unable to function,” said Ms. Hubbard, 52, who began, for the first time, taking psychiatric medication and getting therapy.

In Miami, Victoria Villalba, 44, routinely slept eight hours a night until stories of desperate clients flooding the employment service she runs began jolting her awake at 2 a.m. No longer sleepy, she first began to respond to e-mail, but that caused sleeping colleagues’ BlackBerrys to wake them, so now she studies business books and meticulously organizes her closets.