Clemson Coach Dabo Swinney said quarterback Deshaun Watson, tailback Wayne Gallman and receivers Mike Williams and Artavis Scott, all juniors, would head to the N.F.L. after this season.

Swinney said that the four players would graduate in December and indicated this season would be their last. The four will be honored during Senior Day on Saturday, when the No. 3 Tigers face Pittsburgh.

Watson, a Heisman Trophy candidate, is expected to be among the first quarterbacks taken in next year’s N.F.L. draft. Williams, at 6 feet 3, is also considered a first-rounder.

Last year, Watson became the first player in the Football Bowl Subdivision to throw for more than 4,000 yards and rush for more than 1,000.