A nonpartisan government analysis of the bill that House Republicans have put forward to repeal and replace President Barack Obama's health care law would cause 24 million more people to become uninsured while cutting the federal deficit by nearly $340 billion over the next decade.

The analysis from the Congressional Budget Office, or CBO, was released just two days before the House Budget Committee is set to mark up the legislation, and comes as various lawmakers and interest groups are sharply divided about the future of health care.

The findings are likely to serve as major attack lines on Capitol Hill for groups that are opposed to the American Health Care Act, which has been championed by President Donald Trump's administration and House Speaker Paul Ryan of Wisconsin.

Before the report's release, the American Health Care Act was already facing opposition from multiple corners. Conservative members of the House said the bill doesn't go far enough in undoing the Affordable Care Act, also known as Obamacare, while a number of Republican lawmakers in the Senate have signaled their concerns with the bill as well.

Democrats, meanwhile, are united in their opposition to Republican efforts to dismantle Obamacare, and complained during House committee markups last week that Republicans were charging forward without waiting for the CBO analysis.

When the numbers were released, they pounced on the projections.

“The CBO's estimate makes clear that TrumpCare will cause serious harm to millions of American families," Senate Minority Leader Chuck Schumer, D-N.Y., said in a statement. "Tens of millions will lose their coverage, and millions more, particularly seniors, will have to pay more for health care. The CBO score shows just how empty the president's promises, that everyone will be covered and costs will go down, have been. This should be a looming stop sign for the Republicans' repeal effort.”

Here are some of the key points from the CBO analyisis:

1. By 2026, 52 Million People Total Would Not Have Coverage

The CBO's report projects that if the American Health Care Act becomes law, 14 million more people would not have coverage by 2018 than if Obamacare was to stay in effect.

People will be without coverage, in particular, as a result of the legislation's repeal of the individual mandate obligating people to obtain insurance or pay a fine. Instead of this provision, the Republican-sponsored legislation would allow insurers to charge consumers 30 percent more in their premiums if they let their coverage lapse.

"Some of those people would choose not to have insurance because they chose to be covered by insurance under current law only to avoid paying the penalties, and some people would forgo insurance in response to higher premiums," the CBO report states.

By 2020, the CBO projects that 21 million more people than under current law would be uninsured, and that by 2026 that number would rise to 24 million.

In total, the CBO said an estimated 52 million people would be uninsured in 2026 under the GOP law.

The agency also projected that people with lower incomes and between the ages of 50 and 64 would be disproportionately affected.

The coverage statistics in particular are likely to come as a blow to defenders of the Republican plan. Health and Human Services Secretary Tom Price said on NBC's "Meet the Press" on Sunday that he believed coverage under the plan would improve and that financial burdens would decrease.

Currently, around 29 million people in the U.S. are without health coverage – a decrease of roughly 20 million since Obamacare passed.

"We disagree strenuously with the report that was put out," Price said Monday, arguing that the CBO was not able to look at the whole GOP health plan. Republicans and the White House have said the rollout of the health care bill will come in phases that include administrative changes and an additional effort that would allow states to sell health insurance plans across state lines.

In a statement Monday, Ryan said the CBO report confirms that the measure "will lower premiums and improve access to quality, affordable care."

"Our plan is not about forcing people to buy expensive, one-size-fits-all coverage," he said. "It is about giving people more choices and better access to a plan they want and can afford. When people have more choices, costs go down."

2. Premiums Would Spike Initially

Without the individual mandate, government analysts project average premiums for single policyholders will increase by 15 to 20 percent in 2018 and 2019 under the Republican plan. Because people will no longer have to pay a penalty for going uninsured, fewer healthier people will sign up, which will create an unbalanced risk pool.

By 2020, however, the CBO writes that the increase in premiums will be offset in part by other funding that the law provides and an increased number of younger enrollees. By 2026, average premiums are projected to be 10 percent lower than they would be under Obamacare. Influencing these outcomes are the GOP law's provisions allowing insurers to charge older adults five times more for coverage and providing tax credits to people based on their age, family size and income.

3. Medicaid Spending Would Fall

Under the American Health Care Act, the federal government would set per-person caps in spending on Medicaid beneficiaries rather than match spending each year. Obamacare allowed states to expand the Medicaid program to low-income people, but not all states have opted to act on that provision, thanks to a Supreme Court ruling that made doing so optional. The GOP's health care plan phases out expansion by 2020 in addition to changing the way Medicaid is paid for.

Over the next decade, these changes would decrease direct spending by $880 billion and cause 14 million fewer people to be enrolled in Medicaid.

4. Employer Coverage Would Drop

The report projects that 2 million fewer people would enroll in employer-based coverage in 2020, and that number will grow to 7 million in 2026. This decrease would be linked to the GOP getting rid of the employer mandate that requires companies with 50 or more employees to provide coverage.

5. The Federal Deficit Would Be Cut

The bill is expected to reduce the federal deficit by $337 billion over the next decade, a cut tied to getting rid of Medicaid expansion and repealing Obamacare-created subsidies that help low- and middle-income Americans buy private coverage.

In defending the American Health Care Act against attack, the Trump administration has cast doubt on the CBO's ability to accurately project the effects of such legislation, pointing out out that the agency was off-target in projecting Obamacare's outcomes.

Mick Mulvaney, director of the Office of Management and Budget, told ABC's "This Week" on Sunday that he wasn't sure the CBO was up to the task of analyzing the health bill, saying "sometimes we ask them to do stuff that they're not capable of doing." And Gary Cohn, head of the White House's National Economic Council, said on "Fox News Sunday" that in the past "the CBO score has really been meaningless."

Defenders of the CBO have pointed out that various legal challenges Obamacare faced could not have been predicted, and that its conclusion regarding the overall reduction in uninsurance rates was correct.

In its report, the CBO acknowledged the difficulty of its task.