David Gyasi has joined Natalie Portman in Alex Garland’s “Annihilation” at Paramount Pictures.

“Jane the Virgin” star Gina Rodriguez, Tessa Thompson, Jennifer Jason Leigh and Oscar Isaac will also star with Garland directing and adapting the script based on the Jeff VanderMeer novel.

The story follows a biologist, to be played by Portman, as she embarks on a four-person expedition into Area X, a territory cut off from civilization. While there, she must deal with a mysterious contamination, disappearing colleagues, a deadly animal and a being known as the Crawler, all while searching for clues regarding her husband’s disappearance.

Scott Rudin is producing “Annihilation.” While no release date has been set yet, production is under way.

Gyasi currently stars on the CW sci-fi show “Containment,” which premiered early this month and has already shown ratings growth in its second week.

Gyasi’s past credits include the Wachowskis’ “Cloud Atlas” opposite Tom Hanks, and Christopher Nolan’s “Interstellar.” He is repped by United Agents and Management 360.