Two reputed members of the Lucchese crime family were arrested by the FBI and charged with the murder of a fellow family member — along with the attempted murder of a reputed Bonanno soldier.

Christopher Londonio, 43, and Terrance Caldwell, 58, were charged by federal prosecutors based in Manhattan with the murder of Michael Meldish, a drug kingpin who had been one of the city’s most dangerous criminals.

A federal grand jury in White Plains also indicted Caldwell with attempted murder for his alleged role in the shooting of Enzo “The Baker” Stagno, 47, a reputed Bonanno solider from Whitestone, Queens.

Stagno, whose nickname derives from “The Godfather” character, was struck in the chest in May 2013 as he made a phone call in his SUV near his home, authorities said.

A few months later, Meldish — who had ties to both the Lucchese and Genovese crime families and who once led the notorious Purple Gang in Harlem and the Bronx — was shot in the head as he sat in his luxury car in the Bronx.

It is the first time charges have been brought for the attempted murder of Stagno.

Londonio and Caldwell were already behind bars on Bronx state charges tied to the Meldish murder. Attorneys for the two did not return calls for comment