While TIME’s editors will choose the TIME 100 — our annual list of the most influential people in the world — we want readers to have a say too. Cast your vote here for the movie and television entertainers you think have changed the world this past year, for better or worse. Voting closes at 11:59 p.m. on April 22, and the winner of our reader poll will be announced April 23. This year’s official TIME 100 list will be announced April 24.

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Amy Adams

Nominated four times for the Oscar for Best Supporting Actress, Adams landed a Best Actress nod this year for her lead role in American Hustle .

Louis CK

While everyone eagerly awaited the return of FX's Louie , the comedian inked a deal to develop, write and direct comedy pilots for the network.

Yao Chen

The award-winning actress has used her massive social-media following in China to speak out against the government's censorship of media.

Laverne Cox

The transgender actress was lauded for her performance as hairstylist Sophia Burset on Orange Is the New Black , and she continues to be one of the transgender community's most visible advocates.

Alfonso Cuarón

Cuarón took home Oscars for Best Director and Best Film Editing this year for Gravity , which achieved its visual effects using cutting-edge technology.

Benedict Cumberbatch

It was a marquee year for Cumberbatch, who in 2013 appeared in everything from box-office hit Star Trek Into Darkness to the critically acclaimed 12 Years a Slave .

Lena Dunham

The Girls creator, writer and star is busier than ever, but that hasn’t stopped her from landing a reported $3.7 million book deal and hosting Saturday Night Live .

Megan Ellison

You may not have heard of this 28-year-old indie-film producer, but you’ve probably seen some of the movies she has made happen, including Zero Dark Thirty , Spring Breakers and American Hustle .

Jimmy Fallon

The nicest guy in showbiz brought The Tonight Show back to New York City and perfected an airtight formula for creating viral hits, all while becoming a first-time father.

Jon Hamm

The award-winning actor who wows us as Mad Men' s brooding Don Draper makes the leap to the big leagues with Disney's upcoming Million Dollar Arm .

Kim Kardashian

The reality star seems to be getting everything she wants, thanks to baby North, fiancé Kanye and that much discussed Vogue cover.

Anna Kendrick

You couldn't go anywhere last year without hearing "Cups," the earworm hit sung by the actress in the cult hit Pitch Perfect . And she just won rave reviews for her SNL hosting debut.

Keegan-Michael Key and Jordan Peele

The comic pair keeps us laughing with their eponymous hit sketch series on Comedy Central.

Jenji Kohan

After creating one of the buzziest shows on Netflix, Kohan gets to prove that the series isn't a fluke when the second season is released this summer.

Jennifer Lawrence

America's best friend landed another Oscar nomination for her role in American Hustle and continues to dominate the box office as Katniss in the Hunger Games franchise.

Jared Leto

The multitalented entertainer racked up plenty of golden trophies for his role in Dallas Buyers Club and launched the much discussed man-bun trend.

Matthew McConaughey

From rom-coms to Oscar-worthy, the actor has reinvented himself to become one of Hollywood's most sought-after stars.

Steve McQueen

Capturing hearts and minds with 12 Years a Slave , McQueen is the first African-American director to win Best Picture at the Oscars.

Seth Meyers

The Saturday Night Live alum has stepped out from behind the famous Weekend Update desk and transitioned into a lovable Late Night host.

Lupita Nyong'o

The red carpet's It girl delivered an epic performance in 12 Years a Slave — landing her an Oscar for Best Supporting Actress — and became the new face of Lancôme.

RuPaul

The drag superstar became an unlikely pop star in the '90s, topping charts and becoming the face of MAC cosmetics. Now his Logo series, RuPaul’s Drag Race , is airing its fifth season and attracting celebrity fans like Lady Gaga.

Amy Poehler

The comedian earned legions of fans for her real-girl attitude and funny-girl hysterics, and this year she won Best Actress in a TV Comedy at the Golden Globes for her role on Parks and Recreation — all while hosting the show.

Robert Redford

The film legend, who also founded the Sundance Institute and Film Festival 30 years ago, is — at 77 — still starring in large studio films and indie flicks, all while raising awareness for the environment.

David O. Russell

The film director catapulted Jennifer Lawrence to stardom, earned 10 Academy Award nominations for American Hustle and signed on to a TV drama, his first, with ABC.

Meryl Streep

The legendary actress broke her own record this year with an 18th Oscar nomination for her performance in August: Osage County .

Cecily Strong

The SNL funnywoman was promoted to Weekend Update co-anchor, now opposite Colin Jost.

Kerry Washington

The actress won rave reviews for her performance as D.C. crisis manager Olivia Pope on Scandal , one of ABC's highest-rated shows.

Matthew Weiner

Mad Men begins its seventh and final season this month, a victory lap for a show that has come to stand for the new golden age of television.

Kanye West

The rapper-singer-designer won critical acclaim with last year's Yeezus and nabbed a Vogue cover with fiancée Kim Kardashian.

Shailene Woodley

The 22-year-old star of Divergent has become a press darling in recent months and will appear in The Fault in Our Stars .