Disney/Marvel Studio's "Avengers: Infinity War" wins the domestic box office with an estimated $250 million.

That makes it the biggest opening of all-time, domestically.

Marvel/Disney's long-awaited "Avengers: Infinity War" proved its box office might over the weekend as it took in an estimated $250 million at the domestic box office, according to boxofficepro. That's the biggest of all-time.

The movie that culminates everything that has occurred in the Marvel Cinematic Universe for the last decade since Robert Downey Jr. put on the Iron Man suite in 2008, "Infinity War" follows The Avengers and the Guardians of the Galaxy as they battle the evil Thanos (voiced by Josh Brolin), who wants to possess all the Infinity Stones so he can destroy half of the universe's population.

With the movie's enormously high stakes, fans both super and casual alike of the MCU flocked to the multiplex to see the movie, if not for the simple reason to make sure they weren't left out of the talk on social media and around the office that's to follow.

Thanos in "Avengers: Infinity War." Marvel It's the kind of buzz around a movie that studios dream of — movie that has to be seen on its opening weekend in fear of FOMO. And the weekend numbers are proving that "Infinity War" accomplished its mission.

Following a $106 million Friday (with $39 million from Thursday previews), the movie took a minuscule 25% drop on Saturday, when it took in $83 million. That marks the best Saturday ever (topping $69.6 million by "Jurassic World").

The movie's $250 million weekend passes the all-time best domestic opening weekend held by "Star Wars: The Force Awakens" with $247.9 million in 2015. "Infinity War" playing on more screens (4,474) than "Force Awakens (4,134) helped, too.

"Infinity War" is the sixth movie all-time to have a $200 million-plus opening weekend domestically. They are "The Force Awakens," "The Last Jedi," "Jurassic World," "The Avengers," and "Black Panther."

Yes, all of those properties except for "Jurassic World" are owned by Disney.

The super studio has already earned over $1 billion domestically at the 2018 box office.

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