Dr. Brummel is a Pulmonary and Critical Care physician on faculty at Vanderbilt University and is an expert in delirium and the patient experience in ICU outcomes with a focus on debility or post-ICU syndrome. Dr. Brummel begins his presentation by reviewing long-term cognitive impairment and disability associated with survival from critical illness. He then explains the vulnerability hypothesis his team uses to understand risk factors for the development of these poor outcomes after critical illness. After, he describes preliminary trials of rehabilitation for long-term cognitive impairment after critical illness.