People convicted of commercial drug trafficking offences in Victoria will soon have all their assets seized, not just those bought with the proceeds of crime.

Victoria's Attorney-General Robert Clark said new forfeiture laws to be introduced by the Victorian Government this week would send a message that organised crime did not pay.

"This is a clear and strong penalty for those who engage in large scale commercial drug trafficking, if you are convicted of these offenses you'll lose just about everything you own," Mr Clark said.

"Drug traffickers are peddlers of death and misery, they reap a terrible toll of young lives across the state, it's time to send a message to drug dealers: if you own it, you'll lose it."

Mr Clark said the seizures would apply on top of existing jail terms.

"The new forfeiture law will apply on top of the average 14-year jail term that offenders will face under our baseline sentencing reforms," he said.

"The key difference is that under the new laws there'll be no need to prove that the offender's property came from the proceeds of crime or was used to commit the crime."

'Large commercial quantity' of drugs: 750g: Amphetamine, cocaine, ketamine, methylamphetamine, heroin.

750g: Amphetamine, cocaine, ketamine, methylamphetamine, heroin. 150mg: Lysergic acid diethylamide (LSD)

150mg: Lysergic acid diethylamide (LSD) 5kg: Anabolic and androgenic steroidal agents (other than in implant preparations for use in animals) Full list at: Schedule 11: Drugs, Poisons and Controlled Substances Act.

The legislation would apply to people convicted under the Drugs Poisons and Controlled Substances Act of trafficking a "large commercial quantity" of forbidden substances.

Under the law, a person must be found with a "large quantity" of two or more drugs of dependence to be charged with the offence.

"It doesn't apply to people who have drugs because of their own addiction or even small scale street traffickers," Mr Clark said.

'Mega-rich' with no legal income: Ken Lay

Victoria's Police Chief Commissioner Ken Lay said the law would "redress some of the imbalance" in the justice system.

"You only need to look at some of the recent commentary about people I'd probably describe as mega-rich that have no legal means of income over a very long time," Commissioner Lay told 774 ABC Melbourne.

"This legislation will actually help us have a look at where that money might have come from."

Commissioner Lay said the laws would assist the authorities to seize the assets of convicted criminals like Tony Mokbel.

"I see Mokbel was mentioned on the front page of the paper today and I guess he's one example where we know someone who is very, very wealthy who perhaps hasn't held down a normal job ... for many, many years," he said.

"I know the tax department have had a very good look at it and assets we can tie back to criminal offending, we can get access to through confiscation legislation that is actually linked back to a criminal offence.

"But assets that aren't linked to a criminal offence ... is far more difficult."

But he said the legislation would not allow police to seize unexplained wealth.

"There will be some very tight reigns on this legislation, but we will have the ability to go before the court and actually look at people's wealth and justify where it was derived from," Commissioner Lay said.

He said the Government also needed to allow the police to invest in "forensic accountants, analysts and the like".

"I think we probably need them in-house, there is an amount of work that needs to be done that is enormous to put it mildly, and we would keep these people very gainfully employed for a long, long time," he said.