Republican Sen. Tim Scott Timothy (Tim) Eugene ScottAuthor Ryan Girdusky: RNC worked best when highlighting 'regular people' as opposed to 'standard Republicans' Now is the time to renew our focus on students and their futures GOP lobbyists pleasantly surprised by Republican convention MORE (S.C.) said Monday that, of the Democrats running in the presidential primary, Sen. Bernie Sanders Bernie SandersNYT editorial board remembers Ginsburg: She 'will forever have two legacies' Two GOP governors urge Republicans to hold off on Supreme Court nominee Sanders knocks McConnell: He's going against Ginsburg's 'dying wishes' MORE (I-Vt.) would pose the toughest challenge to President Trump Donald John TrumpUS reimposes UN sanctions on Iran amid increasing tensions Jeff Flake: Republicans 'should hold the same position' on SCOTUS vacancy as 2016 Trump supporters chant 'Fill that seat' at North Carolina rally MORE.

Asked if he thinks Sanders is the biggest threat to Trump right now, Scott told CBS’s Gayle King Gayle KingFauci: Lack of masks at Trump rallies frustrating The Hill's Morning Report - Presented by Facebook - Trump, GOP senators at odds over next stimulus bill Minneapolis police union says members have been 'scapegoated by political leaders' MORE, “I do think so.”

“I would say that the biggest threat to President Trump is President Trump,” Scott added on “This Morning.”

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“If he's on his game, as he was at the State of the Union, I don't think there's a candidate in the country that can beat him,” Scott said of Trump. “If there is a second choice other than himself, it would be Bernie Sanders.”

Scott said Sanders brings “that outsider game in a similar fashion” to what Trump did in 2016, adding that “Republican wisdom said there’s no way in the world out of the 17 candidates, Donald Trump will be the president.”

“The tea leaves suggest that the Democrat Party is looking for every way to stop Bernie Sanders from winning even if he has the plurality; which I think would cause an implosion on the foundation of the Democrat Party,” Scott said.

The vast majority of Democratic officials when asked have said that they will support whoever the nominee is, although some moderates, such as South Carolina Rep. Joe Cunningham Joseph CunninghamWarning signs flash for Lindsey Graham in South Carolina Trump asked Chamber of Commerce to reconsider Democratic endorsements: report GOP leader says he doesn't want Chamber's endorsement: 'They have sold out' MORE (D), have been reluctant to say they would support Sanders if he wins the nomination.

Asked earlier this month if he would support Sanders if he wins the nomination, Cunningham, one of only two Democratic Congress members from the state, told The Post and Courier that “Bernie Sanders will not be the nominee.”

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Scott also told CBS News he believes billionaire Mike Bloomberg would be the easiest candidate for Trump to defeat.

Scott’s prediction comes as Democratic voters in his state prepare to cast their ballots in the presidential primary on Saturday.

Sanders is leading the field after wins in New Hampshire and Nevada and a close second-place finish in Iowa. South Carolina is the first state in the primary with a significant portion of black voters.

The top candidates will face off in a debate Tuesday night in South Carolina ahead of the primary.

Scott said one of Sanders’s opponents has to take him on “head-to-head” in the debate in order for the primary to change.

“You saw Bernie Sanders almost unscathed during the [Nevada] debate. That's perhaps the most dangerous combination you could see on the debate stage. Someone being targeted but the front-runner being left alone,” Scott said, referencing candidates' attacks on Bloomberg. “If things are gonna change for this nation, from a Democrat perspective, someone's gotta take Bernie Sanders on head-to-head tomorrow night. The thriller in South Carolina.”