A Palestinian teen coming home from the swimming pool was killed by Israeli troops on Tuesday as they chased another group of youths who threw rocks at cars and injured a British tourist and his Belgian wife.

A group of young Palestinians hurled stones and Molotov cocktails at cars driving on an Israeli motorway in the occupied West Bank in the early hours of Tuesday morning, according to the Israeli military.

The British man and his Belgian wife were both lightly injured in the attack and were treated and released at a Jerusalem hospital.

Israeli forces pursuing the rock throwers then opened fire on a Palestinian car driving nearby, killing 15-year-old Mahmoud Rafaat Badran and wounding four other Palestinian teenagers.

The Israeli Defence Forces (IDF) said after the shooting that it appeared none of them was involved in the rock throwing.

"From the initial inquiry it appears that uninvolved bystanders were mistakenly hit during the pursuit. The IDF is investigating the circumstances," a spokesman said.