A day after his chief rival picked a woman as a running mate, Republican presidential candidate Donald Trump defended comments he made about Hillary Clinton playing "the woman card" saying the Democrat couldn't even win a local election if she were a man.

"The primary thing that she has going is that she’s a woman and she’s playing that card like I have never seen anybody play it before," he said Thursday on TODAY.

Trump made the controversial comments about Clinton, the Democratic front-runner, during his victory speech Tuesday after easily sweeping up primary wins in five states.

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On TODAY, he said he doesn't see anything wrong with the comments.

"Frankly all I’m doing is bringing out the obvious. Without the woman's card, Hillary would not even be a viable person who could even run for a city council position," he said.

Trump has declared himself “the presumptive nominee,” despite lacking the necessary delegate count and criticized his two GOP rivals for working together to defeat him. On Wednesday, he mocked one of the candidates, Ted Cruz, for boldly tapping Carly Fiorina as a vice presidential running mate despite trailing behind in both primary wins and convention delegates.

Trump also gave his first foreign policy speech, saying his vision for the nation would put “America first” and look strikingly different than the global role the nation plays in the Obama administration.

On TODAY, he addressed how he would deal with the Islamic terrorist group known as ISIS, but revealed few details, saying unpredictability would be a crucial tenet in his approach.

“If I get elected president, I don’t want ISIS to know what I’m going to be doing,” he said.

But Trump wouldn’t dismiss the possibility of using nuclear weapons in his fight.

"I don’t want to rule out anything. I will be the last to use nuclear weapons. It’s a horror to use nuclear weapons. The power of weaponry today is the single greatest problem that our world has,” he said.

“I will be the last to use it. I will not be a happy trigger like some people might be. I will be the last, but I will never ever rule it out.”

Follow TODAY.com writer Eun Kyung Kim on Twitter.