Here are the most significant NFL players who got banged up in Week 12:

Rob Gronkowski, TE, New England Patriots: Gronkowski left the game in the first quarter because of a back injury and was eventually ruled out. ESPN Patriots reporter Mike Reiss had charted Gronkowski as playing seven of 12 offensive snaps before going to the locker room. The TE started on Sunday after missing the Patriots' Week 11 game because of a chest injury. It's unclear when exactly the injury occurred, but Gronkowski dove hard for a deep pass down the seam on his first target of the game. He did not return from the locker room to start the second half.

Derek Carr, QB, Oakland Raiders: Carr appeared to sustain an injury to his right pinkie finger (throwing hand) on a fumbled snap exchange at the beginning of the second half. Carr immediately ran off the field to get evaluated and eventually went to the locker room. Backup Matt McGloin replaced him for one series, before Carr returned to the game with a glove on his throwing hand.

Danny Trevathan, ILB, Chicago Bears: Trevathan limped off the field late in the fourth quarter after his knee appeared to buckle while trying to tackle Titans running back Derrick Henry. Coach John Fox said Trevathan suffered a ruptured right patellar tendon and will miss the remainder of the season. It's the latest in a long string of injuries and suspensions for the Bears, as QB Jay Cutler, WR Alshon Jeffery, OL Kyle Long, pass-rusher Leonard Floyd, LB Jerrell Freeman and more were all absent from Sunday's game.

Lamar Miller, RB, Houston Texans: Miller may have tweaked his left ankle injury on a short catch with 57 seconds remaining in the game. He limped off the field, and did not return to the game. Coach Bill O'Brien did not say anything about the injury after the game.

Ronald Darby, CB, Buffalo Bills: Darby sustained a concussion in the first quarter after a collision with Jaguars RB Chris Ivory. The team ruled him out for the remainder of the game.

Allen Hurns, WR, Jacksonville Jaguars: Hurns scored on a 12-yard catch early in the fourth quarter, his first and only catch of the game. But the WR immediately clutched his hamstring after clearing the goal line and did not return.

John Brown, WR, Arizona Cardinals: Brown was ruled out for the remainder of the game with a hamstring injury in the second half. The speedy wide receiver entered Week 12 ranking third on the team with 30 catches.

DeVante Parker, WR, Miami Dolphins: Parker skied for a 34-yard grab in the third quarter and came down hard on his back. The catch was overturned on review, and the second-year WR was listed as questionable to return with a back injury. Parker did not come back into the game, but he said his injury is "nothing."

Rodger Saffold, OL, Los Angeles Rams: Saffold, who was filling in for benched OT Greg Robinson, left Sunday's game with hand injury and was ruled out. Andrew Donnal took his spot in the lineup. Robinson is expected to be back in the lineup next week.

Chris Ivory, RB, Jacksonville Jaguars: Ivory had nine carries for 44 yards and a touchdown before leaving Sunday's game with hamstring injury in the first quarter. He did not return to the field.

T.Y. Hilton, WR, Indianapolis Colts: Hilton hurt his back on Thursday when he took a hit from Steelers safety Mike Mitchell on a 32-yard completion late in the second quarter. He returned for a play in the third quarter before leaving the game again and being ruled out.

Jordan Reed, TE, Washington Redskins: Reed separated his left shoulder in the first half of the Redskins' Thanksgiving Day showdown against the Cowboys. He played through the pain, scorching Dallas for 10 catches, 95 yards and 2 TDs, but Reed has a Grade 3 AC joint sprain. Jay Gruden said there's still uncertainty over whether the TE will have to miss any time.

Vontae Davis, CB, Indianapolis Colts: Davis entered Thursday's game questionable with an ankle injury. He added to his list of injuries when he hurt his groin trying to defend Steelers receiver Antonio Brown on his 33-yard touchdown in the second quarter. He did not return to the game

Ryan Kelly, C, Indianapolis Colts: Kelly, the team's 2016 first-round pick, left the game in the first quarter with a shoulder injury and did not return to the field.

John Greco, G, Cleveland Browns: Greco left in the third quarter with a mid-foot sprain in his right foot and did not return to the game. Coach Hue Jackson said Greco would be evaluated Monday. The Browns already lost their other guard, Joel Bitonio, to a Lisfranc injury. It's not known if Greco has that same issue.

Odell Beckham Jr., WR, New York Giants: Beckham went to the locker room in the first quarter of Sunday's game. The Giants said he was questionable with a right thumb injury, but he returned after a short time away from the field. The injury comes after Beckham is believed to have stubbed his finger or wrist into the turf last week against the Bears. He finished Sunday's game with six catches, 96 yards and two TDs.

Jeremy Hill, RB, Cincinnati Bengals: Hill was bent back awkwardly while his left ankle was pinned. He hobbled off the field, but the team quickly announced that he was expected to return -- and he did in the second half.