Auburn vs. Ole Miss

Auburn head coach Gus Malzahn celebrates a touchdown on the sidelines during the first half against Ole Miss Saturday, Oct. 29, 2016, at Vaught-Hemingway Stadium in Oxford, Miss. (Julie Bennett/jbennett@al.com)

(JULIE BENNETT)

Riding a five-game win streak, Auburn is a huge favorite in its final SEC home game of the season.

No. 15 Auburn (6-2, 4-1 SEC), which defeated Ole Miss 40-29, opened as a 25.5-point favorite against Vanderbilt, according to VegasInsider.com, for Saturday's game at Jordan-Hare Stadium (11 a.m.).

Vanderbilt (4-4, 1-3 SEC) is coming off an open week, prior to which it defeated Tennessee State 35-17.

The Commodores have won the last two meetings of the teams and lead the all-time series 21-20-1.

Auburn has covered the spread in seven of eight games this season.