LANCE Armstrong plans to admit to doping throughout his career during an upcoming interview with Oprah Winfrey, USA Today reports.

The interview, scheduled to be taped Monday and broadcast Thursday night on the Oprah Winfrey Network, will be conducted at Armstrong's home in Austin, Texas.

Citing an anonymous source, USA Today reported that the disgraced cyclist plans to admit using performance-enhancing drugs, but likely will not get into details of the allegations outlined in a 2012 report by the US Anti-Doping Agency that led to Armstrong being stripped of his seven Tour de France titles and banned for life from the sport.

His representatives declined comment late yesterday, including attorney Tim Herman, but Armstrong sent a text to the Associated Press early Saturday morning saying: "I told her (Winfrey) to go wherever she wants and I'll answer the questions directly, honestly, candidly. That's all I can say."

The New York Times first reported last week that Armstrong was considering making a confession.

The 41-year-old Armstrong, who vehemently denied doping for years, has not spoken publicly about the USADA report that cast him as the leader of a sophisticated and brazen doping program on his US Postal Service teams that included use of steroids, blood boosters and illegal blood transfusions.

Winfrey's network announced on Tuesday that Armstrong agreed to a "no holds barred" interview with her.

A confession to Winfrey would come at a time when some of Armstrong's legal troubles appear to be clearing up.

Any potential perjury charges stemming from his sworn testimony denying doping in a 2005 arbitration fight with a Dallas promotions company over a contract bonus worth US$7.5 million (A$7.1 million) have passed the statute of limitations.

Armstrong faces a whistle-blower lawsuit filed by former teammate Floyd Landis accusing him of defrauding the US Postal Service, but the US Department of Justice has yet to announce if it will join the case. The British newspaper The Sunday Times is suing Armstrong to recover about US$500,000 (A$475,000) it paid him to settle a libel lawsuit.

Armstrong lost most of his personal sponsorship - worth tens of millions of dollars - after USADA issued its report and he left the board of the Livestrong cancer-fighting charity he founded in 1997. He is still said to be worth an estimated $100 million.

Livestrong might be one reason to issue an apology or make a confession. The charity supports cancer patients and still faces an image problem because of its association with its famous founder.

The New York Times reported that Armstrong may make a confession in an attempt to return to competition in elite triathlon or running events, but World Anti-Doping Code rules state his lifetime ban cannot be reduced to less than eight years. WADA and US Anti-Doping officials could agree to reduce the ban further depending on what new information Armstrong provides and his level of cooperation.

Armstrong met with USADA officials recently to explore a "pathway to redemption," according to a report by 60 Minutes Sports aired Wednesday on US network Showtime.