In a press call with Marvel's executive editor Tom Brevoort and writer Rick Remender, it was announced that Apocalypse will return in issue #4 of this fall's Avengers & X-Men: AXIS event comic.

Avengers & X-Men: AXIS #4 cover by Jim Cheung

Avengers & X-Men: AXIS #6 cover by Jim Cheung

Avengers & X-Men: AXIS #5 cover by Jim Cheung

Apocalypse is arguably the X-Men's most powerful and dangerous villain, and he has been absent in his proper form for years. He currently exists as a teenager named Genesis who attends the Jean Grey School, and is in fear of growing up to become the reviled supervillain. Recently in Uncanny Avengers , also written by Remender, a long-brewing plot line featuring the twin offspring of Apocalypse concluded.This news was revealed among other plot details about Act II of AXIS, which will feature "inversions" of major Marvel characters. While we don't know how the inversion event will come about, we do know that these inverted characters will see their moral compass flipped. For example, Sabertooth is a character with a lot of blood on his hands, but he will now be more empathetic and feel the pain of the loss he caused.When IGN asked Remender if Apocalypse is the inversion of Genesis, Brevoort stepped in to say that we’d have to wait for the issue to go on sale. However, Remender did say that the Apocalypse element of AXIS is a climax for the story he wanted to tell with the villain, calling it “the end of my Apocalypse bucket list.” Seeing how Apocalypse has -- in one way or another -- been the overarching villain in both his Uncanny X-Force and Uncanny Avengers series, this is momentous news indeed to hear that years of storytelling will all be coming to a head in AXIS.Here are some other AXIS Act II details dropped in the press call.The character at the bottom of the issue #4 is Kluh -- the inversion of Hulk. And yes, Kluh is Hulk spelled backwards.The inversion will be how Tony Stark becomes Superior Iron Man. His new series will spin out of AXIS. His move to San Francisco was sparked by Remender's time living there and his fascination with the "Tech Junkies" versus the "Punkers" who live there. As you can see in the cover below, fellow SF resident Daredevil won't be happy with this new Iron Man.Big changes are coming for lots of characters like Deadpool, Magneto, Loki, and Scarlet Witch. As you can see from the cover above, Scarlet Witch receives a big moment that goes back to House of M and Avengers: Children's Crusade, comics that Remender went back and read in order to respect their continuity and provide some resolution in the form of certain characters getting revenge.Carnage and Hobgoblin will both be receiving an AXIS mini-series featuring their inverted, good selves. Remender teased that even when Carnage is trying to be heroic, bloodshed inevitably occurs.AXIS will be Sam Wilson’s first big event as Captain America. Remender said he has a huge role in AXIS, including a big fight between him and the X-Men, which doesn’t go right for anybody.What do you think of the return of Apocalypse? What about the continuing slow trickle of AXIS news -- anything catch your interest? Let us know in the comments!

Joshua is IGN’s Comics Editor. If Game of Thrones, Spider-Man, or Super Smash Bros. are frequently used words in your vocabulary, you’ll want to follow him on Twitter and IGN