The Queensland Government is guaranteed $1 billion in revenue from the new $3 billion Queen's Wharf casino development, which was finally signed off on Monday morning by Premier Annastacia Palaszczuk.

Most of that revenue - $880 million - comes after the casino has been operating for 10 years.

Ms Palaszczuk told reporters the first instalment of $272 million would begin to be paid to the Queensland Government on Monday.

"Another guaranteed $880 million will follow from casino taxes over the first 10 years of Destination Brisbane Queensland's operations from 2022," Ms Palaszczuk said.