Steve Connor

The Independent

April 14, 2008

A new form of cloning has been developed that is easier to carry out than the technique used to create Dolly the sheep, raising fears that it may one day be used on human embryos to produce “designer” babies.

Scientists who used the procedure to create baby mice from the skin cells of adult animals have found it to be far more efficient than the Dolly technique, with fewer side effects, which makes it more acceptable for human use.

The mice were made by inserting skin cells of an adult animal into early embryos produced by in-vitro fertilisation (IVF). Some of the resulting offspring were partial clones but some were full clones – just like Dolly.

Unlike the Dolly technique, however, the procedure is so simple and efficient that it has raised fears that it will be seized on by IVF doctors to help infertile couples who are eager to have their own biological children.

One scientist said this weekend that a maverick attempt to perform the technique on humans is now too real to ignore. “It’s unethical and unsafe, but someone may be doing it today,” said Robert Lanza, chief scientific officer of American biotechnology company Advanced Cell Technology.

“Cloning isn’t here now, but with this new technique we have the technology that can actually produce a child. If this was applied to humans it would be enormously important and troublesome,” said Dr Lanza, whose company has pioneered developments in stem cells and cell reprogramming.

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