A SENATE inquiry into the Queensland Government would be devastating for the state and would lead to people spending time in prison, according to maverick independent Dr Alex Douglas.

Dr Douglas said yesterday he had already conducted six major investigations and had submitters ready to give evidence before he quit as state leader of the Palmer United Party over a candidate pre-selection conflict with the party's federal leader Clive Palmer.

The former National Party and LNP stalwart remains a supporter of PUP's bid for a Senate inquiry into this state's politics.

Dr Douglas listed changes to Queensland's integrity watchdog, what he described as a "stacking" of the judicial system, the Newman Government's asset sale program and a reduction in the level of scrutiny afforded by new estimate hearing arrangements as creating the need for external scrutiny.

"There are people lined up ready to go,'' he said. "I'm confident the Senate inquiry will get the go ahead.

"The government has brought this on itself."

Dr Douglas revealed he has 50 "very good people" ready to stand in seats at the next Queensland election who would provide viable options to Labor or the LNP.

The Australian Labor Party looks set to back Mr Palmer's push for a Senate inquiry into the Newman Government with a decision expected to be made soon.

A similar inquiry was pushed through by the Nationals and Liberals in 2007 to hear submissions on Beattie government plans to build the Traveston Dam.

The Premier did not response directly to questions put about Dr Douglas's comments.

Instead a media adviser pointed to an earlier response by Mr Newman to questions about the proposed PUP-sponsored Senate inquiry.

"Well, look, I'm focused on getting the Queensland economy going and revitalising frontline services like health and education, '' he said.