Younis Khan has been ruled out of Pakistan's first Test against West Indies, with doctors advising him 10 days of rest to regain his strength after recovering from a bout of dengue fever.

"Younis has informed chief selector Inzamam-ul-Haq that he won't able to play the first Test," a PCB spokesperson told ESPNcricinfo. "The selectors are yet to announce the squad, but its is confirmed that Younis will not take part in the opening game in Dubai. He asked for rest to be fully fit before his national selection since he has recently recovered from dengue."

Last month, the 38-year-old Younis contracted a high fever that was later diagnosed as the mosquito-borne disease dengue, for which he was treated in a Karachi hospital. This forced him to miss the first round of the Quaid-e-Azam Trophy, Pakistan's premier first-class tournament. Doctors have advised Younis to extend his rest for another 10 days. He is expected to be available for the second Test in Abu Dhabi.

Younis last missed a Test match in May 2011 - also against West Indies, coincidentally, in St Kitts - and has since featured in 41 successive matches, scoring 3839 runs in that period, at an average of 59.06. He is now Pakistan's leading run-getter in Tests with 9456 runs at 53.72, and in his last appearance scored 218 against England at The Oval.

Pakistan will begin their three-match Test series with a pink-ball, day-night match at the Dubai International Stadium from October 13. The second Test begins on October 21 in Abu Dhabi, and the third in Sharjah on October 30.