A man has died with critical injuries after his motorbike and a vehicle collided on the Brisbane Valley Highway in Queensland's Somerset region.

Attempts were made to save the 52-year-old male rider from Boronia Heights but he was dead at the scene.

Emergency services called were just after 5am on Wednesday near Wanora Road, Wanora - west of Brisbane.

The crash between a motorbike and a crash occurred on the Brisbane Valley Highway. Credit:Google Maps

QAS senior operations supervisor Mark Nugent said the driver of the vehicle, a 52-year-old man from Glamorgan Vale, was taken to Ipswich Hospital in a stable condition, with a shoulder injury.