: : Expect (if using Bisacodyl) to put one in and not feel much for maybe five or ten minutes which will usually convince you another one could not hurt. You might be better off to wait another ten minutes or so though before adding to this time bomb. Two or even three with one given every fifteen minutes will be do-able, but very shortly after inserting the third the urge will become more than you can resist and after the first expulsion you will be wondering what you have got into because you will have to go just as bad but it isn't coming out. This intense urge to go will continue for perhaps as much as an hour or more and will leave you pretty weak and really feeling wrung out and empty. An enema will help but once Bisacodyl is in your bowel and the membranes are responding to the Bisacodyl the urge will continue till all of the Bisacodyl is expelled - it is an powerful, stimulant laxative, and your bowel will respond to it very vigorously - whether you will enjoy this or not is a very individual thing. I would recommend starting slow and giving it some time because you can easily increase the action with one more - but once you have gone too far with this it won't really hurt you - but you will be one unhappy camper if too much is used the first time. Trust me on this.