Washington(CNN) Vermont independent Sen. Bernie Sanders will headline MoveOn.org's "Don't Take Our Health Care" bus tour this weekend, making stops in various East Coast states to challenge the newly released Senate health care bill.

With planned stops in Pittsburgh, Pennsylvania, Columbus, Ohio and Charleston, West Virginia, Sanders and leaders at MoveOn -- a progressive public policy advocacy group -- will speak at rallies urging GOP senators to save the Affordable Care Act and challenging Republican talking points that the alternative to Obamacare is a better option for Americans, according to Brian Stewart, director of media relations at MoveOn.

The tour is additionally designed to put pressure on the Republican senators in those states -- specifically, Sens. Pat Toomey of Pennsylvania, Rob Portman of Ohio and Shelley Moore Capito of West Virginia -- to vote against the Senate bill when it comes to the floor next week.

Sanders has called the Senate's health care bill "the most harmful piece of legislation" he's ever seen, and in the past warned that "thousands would die" if it passes.

"The Republican plan is even worse than expected and by far the most harmful piece of legislation I have seen in my lifetime," Sanders said in a statement provided to CNN. "This bill has nothing to do with health care. It has everything to do with an enormous transfer of wealth from working people to the richest."

Following the House GOP's failure in March to pass its first version of a health care bill, Sanders said he was planning to introduce legislation that outlined a "Medicare-for-all, single-payer" health care plan.

"Ideally, where we should be going is to join the rest of the industrialized world and guarantee health care to all people as a right," Sanders told CNN.

Such a plan would likely face certain defeat in Congress. Sanders also acknowledged that "Obamacare has serious problems."

"Deductibles are too high," Sanders said. "Premiums are too high. The cost of health care is going up at a much faster rate than it should."

MoveOn has made saving Obamacare a main focus since President Donald Trump took office.

"No matter what back-room deals senators make in the coming days, there is no way to fix this shocking and cruel bill," said Anna Galland, executive director of MoveOn.org about the GOP health care bill. "Senators have a choice: stand up for your constituents and protect their health care, or go down in history as the people who ended Medicaid, slashed Planned Parenthood and raised health care costs for your constituents."

The Congressional Budget Office is expected to release its scoring of the proposed legislation early next week and senators are expected to vote on the legislation shortly afterward.