Iran’s supreme religious leader Ayatollah Ali Khamenei, in a series of threatening tweets Wednesday, said Israel would not survive the next 25 years and Iran would reject any negotiations with the U.S., or the “Great Satan,” beyond the nuclear deal.

An image posted to Mr. Khamenei’s official Twitter account shows the Iranian leader walking on an Israeli flag painted on the sidewalk. In a quote accompanying the photo, Mr. Khamenei says Jewish state will not make it past the next 25 years and vows that Israel will be hounded until it is destroyed.

“After negotiations, in Zionist regime they said they had no more concern about Iran for next 25 years; I’d say: Firstly, you will not see next 25 years; God willing, there will be nothing as Zionist regime by next 25 years. Secondly, until then, struggling, heroic and jihadi morale will leave no moment of serenity for Zionists,” the quote from Iran’s top leader reads in broken English.

The quote reportedly comes from a speech the religious leader made earlier in the day, The Times of Israel reported.

In addition, Mr. Khamenei addressed Iran’s relationship with the U.S. following the signing of a nuclear deal in July, saying Tehran would not allow any other negotiations with the “Great Satan” beyond the nuclear talks.

“US officials seek negotiation with #Iran; negotiations is means of infiltration and imposition of their wills [sic],” Mr. Khamenei tweeted.

“We allowed negotiations with the US only on nuclear issue for certain reasons, in other areas we did not and will not allow negotiations with US,” he added.

In the final remark in the series of tweets, the Iranian leader said Iran would negotiate and reach “agreement in different levels of ‘state religious or ethnic groups’ with all countries but the Great Satan.”

The remarks come as Congress reconvened on Wednesday to debate supporting the new nuclear deal between Tehran and other world powers. Opponents of the deal point to Iran’s anti-U.S. and anti-Zionist rhetoric as evidence that the Islamic Republic can’t be trusted to uphold it’s end of a nuclear deal.

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