The Syrian government has accused Turkey of escalating the complex war in Syria by carrying out air strikes near Aleppo, warning that further Turkish planes in Syrian airspace will be “brought down by all means available.

The Turkish air force struck 18 different Kurdish targets in Maarraat Umm Hawsh near Aleppo on Thursday, killing up to 200 soldiers. Ankara has significantly escalated its military presence in the Syrian civil war since August, successfully driving out Isis from the border region and attempting to curb Kurdish efforts at territorial expansion, which it sees as a threat to Turkish sovereignty.

The Syrian Defence Ministry released a statement on Thursday accusing Turkey of “flagrant aggression, which targeted innocent citizens,” warning Turkey’s incursions deeper into Syria are “a dangerous development that could escalate the situation.”

“Any attempt to once again breach Syrian airspace by Turkish war planes will be dealt with and they will be brought down by all means available,” the statement said.

Turkish-backed Syrian Sunni rebel groups and Kurdish militias have been fighting for control of areas their combined strength has managed to recently retake from Isis.

The situation is also likely to further inflame Turkey’s relations with the US since the Nato allies disagree over the role of Kurdish forces in the Syrian and Iraqi conflicts.

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The US State Department distanced itself from from Ankara’s actions on Thursday. “Contrary to some reports, US was not involved in Turkey airstrikes last night,” spokesperson John Kirby said, adding that uncoordinated movements “only benefit” Isis.