I was actually considering Sasuke x Akame at one point but, ended up choosing Sasuke and Blake instead. I always thought that they would be more suited together since they are both trying to make amends of what they have done in the past and also due to both of their connection to a certain blonde who knocked some sense into them when they were both at their lowest point, not to mention Sasuke's time spent with Nekobaa. I thought Akame and Hiei would be suited to each other considering that there most important people in their lives would be their sister. While Akame is trying to save Kurome by killing or pursuading her, Hiei is giving protection to his sister by hiding his identity to Yukina, considering he lives he has killed and the demons who would like to take his life.