NFL Nation reporters rely on their expertise gleaned from their teams' offseason activity, training camp practices and four preseason games to bring you bold predictions for the 2016 regular season.

AFC East | AFC North| AFC South | AFC West

NFC East | NFC North | NFC South | NFC West

AFC EAST

The Bills will start the season 0-4.

Crazy? Consider that the Bills must play a tough opening-weekend game at Baltimore, then host the Jets on short rest, then play two of the final four teams from last season (the Cardinals and the Patriots), and 0-4 seems possible. Without Marcell Dareus, Reggie Ragland and Shaq Lawson, the Bills will have to find ways to plug holes on defense and avoid falling far behind early in the season. If they finish the first quarter of the season winless, coach Rex Ryan will need to dig out of a monumental hole to finish the season with a winning record and allow him to rest easy about his job security. -- Mike Rodak

Dolphins receiver DeVante Parker will notch his first 1,000-yard season of his career.

Parker has all the tools but must stay healthy for a full season, which has been an issue. Parker notched 445 receiving yards and three touchdowns in the final six games of 2015, which will provide confidence and momentum for this season. He is also Miami's best deep threat and will get the most opportunities to make big plays. -- James Walker

The Patriots will go 3-1 with Jimmy Garoppolo as their quarterback to open the season.

Some have said Garoppolo just needs to keep the team afloat, but I think he'll do a little better than that and help the team to a strong start. It might be a season-opening loss at Arizona, but home games against Miami, Houston and Buffalo are winnable, and Garoppolo has the tools to succeed. -- Mike Reiss

The Jets will put three defensive linemen in the Pro Bowl -- Muhammad Wilkerson, Sheldon Richardson and Leonard Williams.

The former first-round picks are all healthy and they should thrive in the Jets' scheme, which uses multiple fronts. Wilkerson and Richardson already have Pro Bowls on the résumé (Richardson was an alternate in 2014) and Williams is poised for a breakthrough. -- Rich Cimini

AFC NORTH

Joe Flacco will reach his first Pro Bowl.

He is primed to set career highs in passing yards and touchdowns. Flacco has more speed on the outside than he has ever had in Mike Wallace, Breshad Perriman and Chris Moore. He has a motivated Steve Smith Sr., who is entering what should be his final NFL season. And he is being protected by a franchise left tackle for the first time in his career. It should be noted that Flacco had a chance to go to the Pro Bowl as an alternate after the 2014 season, but he declined because his third child was due to be born. -- Jamison Hensley

The Bengals will win a playoff game for the first time since 1990.

Hold your skepticism please. A healthy Andy Dalton can pick up from where he left off last season, and even though he doesn't have as many targets as he used to have, having one of the NFL's best receivers in A.J. Green just might be enough. The Bengals learned a lesson in how to control their emotions in their wild-card loss to the Steelers. After four years of double-digit wins and playoff appearances but no wins, this is the year they break through. Hey, it has to happen sometime right? -- Katherine Terrell

The Browns' defense may set records this season it wants no part of.

Cleveland's defense will struggle and become the sixth team in team history to give up more than 400 points. This defense also will push the team record of 462 points allowed, a mark set in 1990. -- Pat McManamon

Ben Roethlisberger will make his biggest push yet for a league MVP, and he just might win it.

The veteran QB will definitely have the yards. What he needs is more touchdowns (career high is 32). The Steelers have been clamoring for improved red-zone play the past two years, but if Roethlisberger pairs, say, 35 scores with 10 or more Steelers wins, he'll be hard to beat in this category. He's accurate while taking chances, and he's the glue once again as the offense deals with injuries and suspensions for the second straight year. -- Jeremy Fowler

AFC SOUTH

Running back Lamar Miller will finish the season in the league's top three in rushing yards.

During his four seasons with the Dolphins, Miller was underused, topping 200 carries in a season only once, and was not given the chance to be a three-down back. In Houston, expect that to change. -- Sarah Barshop

QB Andrew Luck will rebound from the worst season of his NFL career to throw for a career high in passing yards and touchdowns.

And Luck will top the 4,761 yards and 40 touchdowns he had in 2014. And more importantly, a healthy Luck will lead the Colts back to the playoffs for the fourth time in five seasons. -- Mike Wells

The Jaguars will be 4-3 by November.

Why is that a bold prediction? The team is just 3-20 in games played in September and October in the past three seasons under coach Gus Bradley. Going with the 4-3 record, it will mark the first time the Jaguars have been over .500 heading into November since 2007, which was the last year the team make the playoffs. -- Mike DiRocco

Marcus Mariota will be a top-10 quarterback in passer rating, with a good completion percentage, more TDs than his 19 as a rookie and fewer than his 10 interceptions.

Mariota has a year's worth of experience, a better offensive line, a running game that will make the Titans rely on him less and upgraded weapons to throw to. His solid passing stats will be supplemented by some effective running. -- Paul Kuharsky

AFC WEST

The Broncos will win their sixth consecutive division title.

Yes, the Chiefs believe they're better, the Raiders believe they're better, but unless either of those teams can solve the Broncos' defense enough to win a game in Denver, the Broncos will take the AFC West title again. Sure, that's bold with two quarterbacks on the roster who have yet to throw a pass in the regular season in Trevor Siemian and Paxton Lynch, but the Broncos' defense powered a championship run last season and returns nine starters and looks every bit the part once again. If their offense is even marginally better, the Broncos will rule the AFC West again. -- Jeff Legwold

The Chiefs will win their first AFC West championship since 2010.

If that isn't bold enough, the offense will lead the way. Quarterback Alex Smith will set a career best for touchdown passes -- the bar is currently a modest 23 -- and the play of the line will be another key factor. -- Adam Teicher

The Raiders will be in the playoffs for the first time since 2002.

Yes, go ahead, cue up your Jim Mora sound bites and revel in the news. The Raiders have an exciting young nucleus in place with the likes of QB Derek Carr, WR Amari Cooper and DE Khalil Mack and spent the offseason surrounding it with quality veteran free-agent signings such as LG Kelechi Osemele, OLB Bruce Irvin, CB Sean Smith and FS Reggie Nelson. The division is up for grabs, and with the Broncos' unsettled QB question, the Chiefs prone to slow starts and the Chargers, well, still the Chargers, it's time for a Raiders return to the postseason ... even if it's as a wild card. -- Paul Gutierrez

The Chargers will finish as a top-10 defense in 2016.

San Diego has not finished among the league leaders in total defense since 2010, when the Chargers led the league in total defense. But with the addition of nose tackle Brandon Mebane in free agency and finally signing rookie draft pick Joey Bosa, along with the continued development of cornerback Jason Verrett and linebacker Denzel Perryman, San Diego is primed to make noise on that side of the ball this season. -- Eric D. Williams

NFC EAST

Dak Prescott will have more touchdown passes than interceptions in his time as the Cowboys' starter in Tony Romo's absence.

Not bold enough for you? Since 1980, two fourth-round picks have started season openers: Chris Weinke in 2001 for the Carolina Panthers and Kyle Orton for the Chicago Bears in 2005. Weinke went 1-14 and had 11 touchdown passes and 19 interceptions. Orton had nine touchdown passes and 13 interceptions but had a 10-5 record. If Romo is placed on injured reserve and can't return until Nov. 6, then Prescott will have 10 touchdown passes and six interceptions. -- Todd Archer

The Giants finish top five in sacks.

It's a massive accomplishment given their struggles reaching the quarterback last season, when they finished 30th in the NFL with 23 sacks. But this season defensive ends Olivier Vernon and Jason Pierre-Paul will get close to that number alone. Vernon is primed for a breakout statistical season, and with some young depth behind them on the line (Owa Odighizuwa and Kerry Wynn), there will be constant pressure on quarterbacks. What a difference one year and more than $200 million spent on the defense makes. -- Jordan Raanan

The Eagles' defense will lead the league in sacks.

Jim Schwartz got his Buffalo Bills unit to do just that in 2014 (54 total sacks) when he was the defensive coordinator there. He allows his players to attack, which should be good news for Fletcher Cox, Vinny Curry, Brandon Graham and company now that he's in Philly. -- Tim McManus

Kirk Cousins will become the first quarterback in franchise history to throw for at least 29 touchdowns in consecutive seasons.

He also will throw more than the 11 interceptions he did last season. But with excellent weapons around him in tight end Jordan Reed and receivers Pierre Garcon and DeSean Jackson, among others, Cousins will have plenty of chances to look good. Beware big plays on first down play-action throws. -- John Keim

NFC NORTH

Chicago Bears

Alshon Jeffery is playing his final season in Chicago.

Unless the Bears use the franchise tag on Jeffery again next offseason (which they are permitted by league rules to do), the receiver will test the open market in free agency. The Bears had the chance to lock up Jeffery long-term, but declined, in part because Jeffery missed seven games in 2015 due to a variety of soft tissue injuries. However, Jeffery can put up big numbers, when healthy. The best guess is Jeffery stays on the field and produces in 2016, and cashes in somewhere else in the spring. -- Jeff Dickerson

Ezekiel Ansah will become a star and lead the NFL in sacks.

After finishing third in the league in sacks (14.5) last season, he has looked even sharper during training camp. The Lions' line is potentially better than it was a season ago as well, meaning teams might have to double-team him less, particularly if Devin Taylor and Tyrunn Walker play up to their capabilities. That could leave opposing offensive tackles unhappy if they have to deal with Ansah in single coverage because he'll win that most of the time. Put him down for 18 sacks in 2016 and in the conversation as one of the best defensive players in the league.-- Michael Rothstein

Aaron Rodgers will win his third MVP award, tying Brett Favre.

Think about it: Rodgers has his best receiver, Jordy Nelson, back from his knee injury, and running back Eddie Lacy appears primed for another 1,100-yard season like he had in 2014. The last time Rodgers had Nelson and an 1,100-yard back, he won the MVP in 2014. Throw in the addition of big-play tight end Jared Cook and a healthy offensive line, and Rodgers has as good a chance as anyone. -- Rob Demovsky

Even without Teddy Bridgewater, the Vikings will still make the playoffs.

Their defense figures to be one of the best in the league, they still have Adrian Peterson and coach Mike Zimmer seems to thrive on situations where most people count his team out. The Vikings weren't built around a prolific passing game last season; they won the NFC North with the league's 31st-ranked passing offense, so they're not expecting Sam Bradford to carry the team days after he arrived in Minnesota. It won't be pretty, but they'll find a way to get back to the playoffs. -- Ben Goessling

NFC SOUTH

Julio Jones will become the first player in NFL history to reach 2,000 receiving yards in a single season.

Jones had 1,871 yards last season, the second-highest total in league history. And he accomplished that on 136 catches. The record-holder, retired Calvin Johnson, had 1,964 yards on 122 catches in 2012. I could see Jones having fewer catches because of the additions of Mohamed Sanu and rookie tight end Austin Hooper in the passing game. At the same time, I could see Jones putting up more yards because the Falcons vow to throw more deep balls this season. Said Jones, "If that's me getting 2,000 on the way to being a great teammate, let's do it." -- Vaughn McClure

Carolina Panthers

Quarterback Cam Newton will become the first player since Peyton Manning in 2008-09 to win consecutive NFL MVP Awards, putting up better numbers than he did a year ago.

The return of No. 1 wide receiver Kelvin Benjamin and the emergence of second-year receiver Devin Funchess should produce even more touchdowns for Newton inside the red zone, giving Newton the opportunity to surpass his career-best 35 TD passes in 2015. -- David Newton

Drew Brees will lead the NFL in passing yards.

OK, maybe that's not so bold a prediction since Brees has already done that in four of the past five seasons. But people keep expecting some regression from the 37-year-old. Instead, I say the Saints' passing offense will be even more dynamic, with rising receivers such as Brandin Cooks, Willie Snead and Michael Thomas keeping Brees young. The biggest hurdle will be the questionable guard play, which looked shakier this preseason than it has at any point in Brees' tenure. -- Mike Triplett

The Bucs will finish at or above .500 for the first time since Raheem Morris' 10-6 season in 2010.

QB Jameis Winston is in his second year in Dirk Koetter's offense, which finished fifth in the league in yardage last season. Winston has a healthy Vincent Jackson, he's improved his chemistry with Mike Evans and he has a true third receiver in Adam Humphries. The defense -- an area the team struggled with last season -- has two new pass-rushers up front in Robert Ayers and Noah Spence, with four-time Pro Bowl cornerback Brent Grimes and first-round pick Vernon Hargreaves III manning a revamped secondary. If the stars align for Koetter in his first year as head coach, those changes are enough to buy this team two, possibly even three more wins. -- Jenna Laine

NFC WEST

The Cardinals will win the NFC West, win the NFC title and play in Super Bowl 51.

Maybe that prediction isn't so bold, but it's a little brash. Arizona will have the league's best offense, led by a healthy Carson Palmer, who will be a contender for NFL MVP. The spotlight and target is on the Cardinals this season after making it to the NFC Championship Game last season and then getting their every move featured on a documentary series streamed on Amazon this past offseason. A lot of eyes will be on the Cards. -- Josh Weinfuss

Todd Gurley will lead the NFL in rushing.

Perhaps that doesn't sound so bold, considering Gurley finished third in rushing (1,106 yards) as a rookie last season. But consider: Gurley averaged a pedestrian 63 yards per game over his final seven weeks in 2015, with defenses stacking the box to close up his holes. The bet here is that the Rams' offense will display just enough of a passing threat to give their star running back the space he needs for big gains. By season's end, Gurley will be crowned the new rushing champion. He'll certainly have plentiful opportunities. -- Alden Gonzalez

Defensive lineman DeForest Buckner will make good on his goal to win Defensive Rookie of the Year.

Buckner put that individual goal out there before training camp even started, then went out and showed the potential to make it happen throughout the preseason. His position doesn't always lend itself to big stats, but Buckner should get the playing time and opportunity to be an immediate difference-maker for the 49ers' defense and bring home some hardware. -- Nick Wagoner

This team will get back to the Super Bowl for the third time in four years.

Russell Wilson, 27, is in his prime after having led the NFL in passer rating last season, and he returns his top four receivers. The defense has allowed the fewest points in the league for four straight seasons and is loaded with talent. And the Seahawks have continuity on their coaching staff and in the front office. Last year, they were coming off of the most devastating loss in Super Bowl history, and Kam Chancellor held out the first two games of the regular season. They still went 10-6 and advanced to the divisional round of the playoffs. This is a mentally tough group. They need to get competent play from the offensive line and avoid significant injuries, but if those two things happen, the Seahawks are positioned to go on a run and play for a championship in Houston. -- Sheil Kapadia