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AURORA, Ont. – Police say they’ve taken down two crime rings that allegedly distributed illicit drugs throughout Ontario.

York Regional Police say in one investigation, an Asian crime group manipulated the medicinal marijuana licensing system.

READ MORE: Major players in alleged Italian crime family taken down in massive bust in Ontario

They allege the groups ran a sophisticated operation that included several large pot farms in the province.

Police say the group used marijuana sales to fund the manufacture of methamphetamine, ecstasy, marijuana resin and mushrooms.

WATCH: Accused in 2018 drug bust ‘rearrested’ in recent investigation: York Regional Police

0:40 Accused in 2018 drug bust ‘rearrested’ in recent investigation: York Regional Police Accused in 2018 drug bust ‘rearrested’ in recent investigation: York Regional Police

The second probe focused on a home in Vaughan, Ont., and led to a large seizure of fentanyl, cocaine and methamphetamine.

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Police say they have charged more than 50 people.

At @YRP HQ where investigators are unveiling the details of Project Zen. $45 million worth of drugs and guns seized. Illegal cannabis, methamphetamines, hash, GHB and the equipment used in making it. Police say this is also the largest fentanyl bust in YRP history. pic.twitter.com/O73Lk2kQCZ — Mark Carcasole (@MarkCarcGlobal) August 8, 2019