SANTA ANA – First, comedian Roseanne Barr blazed trails with her sitcom; more recently she joined the growing reality TV world as she farmed macadamia nuts in Hawaii.

Now the onetime presidential hopeful whose slogan was ‘Yes, we Cannabis!’ is entering the budding medical marijuana industry – in Santa Ana.

Barr will be an investor and have a licensing agreement with a dispensary that’s one of 20 that won a city lottery last year allowing it to apply to operate in Santa Ana, the actress’ spokesman and the dispensary’s partners said this week.

The dispensary will be called Roseanne’s Joint and will sell marijuana products bearing its name, said partner Aaron Herzberg, 46. It will feature Barr’s unique pot strains and products such as pot-laced, chocolate-covered macadamia nuts grown on her farm, he said.

The actress also will make occasional appearances there, he said.

“I’m proud to be a cultural pioneer at the forefront of another wave of progress! And we’re proud of the city of Santa Ana as we continue to move into the era of recognizing cannabis as the natural, therapeutic, herbal substance medical science has proven it to be,” Barr said in a statement. “Roseanne’s Joint will be a responsible, contributing member of, and addition to, the community.”

Barr wasn’t available for an interview this week, her spokesman James Moore said.

Barr joins a growing number of celebrities trying their hand at medical marijuana ventures, in Santa Ana and beyond. Cypress Hill rapper B-Real was the first celebrity to jump into the local pot scene when his dispensary was among those to win Santa Ana’s dispensary license lottery.

Last week, actor Woody Harrelson applied for a marijuana dispensary license in Hawaii. Other celebrities already associated with marijuana reportedly are getting into the industry in one form or another – including actor Tommy Chong, rapper Snoop Dogg and the family of singer Bob Marley.

It was a “natural, easy kind of conversation” bringing Barr on board, Herzberg said, because he was her attorney half a dozen years ago and they became friends. After Herzberg got involved in the weed industry a few years ago, Barr – who in 2012 pursued the presidential nominations of the Green Party and Peace and Freedom Party and was vocal about legalizing marijuana – was “excited” and decided to get involved, he said.

Last year, Barr, 63, revealed she is consuming medical marijuana to fight glaucoma and macular degeneration that are causing her to gradually lose her eyesight.

“We think it will bring credibility and a good name and frankly, good values,” Herzberg said. “But we also hope that it will create within the community a sense that marijuana is here to stay in California, that it’s getting legitimized and that serious names are coming to the table.”

The oldest child in a working-class, Jewish Salt Lake City family, Barr began her career as a stand-up comedian before rising to fame for her role in the sitcom “Roseanne,” a hit from 1988 to 1997 that earned her an Emmy and a Golden Globe for best actress.

She has “been involved in the design process personally,” Herzberg said, and has asked that the dispensary offer customers “a very high-end, premium experience with very rustic wood floors and a very open environment.”

An incomplete application for a regulatory safety permit, which gives approval to open, is on file with the Santa Ana Police Department for the Roseanne’s Joint address, 1327 E. St. Gertrude Place, said police Commander Chris Revere. A similar application has been filed for B-Real’s dispensary, Dr. Greenthumb, which is a reference to one of his songs.

Of the 20 dispensaries selected in the lottery, 10 have been issued regulatory safety permits, six have applied for a permit and are in the background process or have submitted incomplete applications, and four have not submitted any application, according to Revere.

Herzberg said construction for Roseanne’s Joint could be completed by late April, a necessary element to receive the regulatory safety permit, and the dispensary could open shortly afterward. Prices will have to be competitive, he said, because licensed dispensaries pay taxes to the city, unlike rogue stores.

Dispensary partners see Roseanne’s Joint as only the start.

Barr’s licensed products could someday be distributed at other stores and she could be involved in other pot shop ventures, Herzberg said.

There’s also greater potential within Roseanne’s Joint, said Chris Francey, 32, the other partner in the dispensary.

The building is 5,000 square feet, about three times the average dispensary size, said Francey, who’s already opened his first medicial marijuana shop in the city, OC3 at 3122 S. Halladay St. He and Herzberg said they hope the city will consider allowing cultivation or a coffee shop operation at licensed dispensaries.

Herzberg said Barr is a serious supporter of the benefits of marijuana.

“She’s very spiritual, she’s very holistic, she’s extremely into natural remedies, and I can tell you that she believes very strongly that marijuana is medicine,” Herzberg said. “And she wants us to educate patients in a way that I don’t think many other dispensaries are doing and make it a safe and comfortable environment.”

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