Kara Zor-El will take flight on Mondays this fall.

CBS on Wednesday revealed its primetime schedule for the 2015-16 TV season, and the big news is that Supergirl will assume Monday’s formerly comedy-dominant opening hour after Thursday Night Football ends in early November.

Also of note: New family comedy Life in Pieces has scored the plum post-Big Bang slot (first on Mondays and then on Thursdays after TNF concludes), and new drama Limitless takes over Person of Interest‘s Tuesday-at-10 perch (the latter is being held for midseason),

Also on deck for midseason: Returning shows 2 Broke Girls, Mike & Molly, Undercover Boss and The Odd Couple, and new dramas Rush Hour and Criminal Minds: Beyond Borders.

CSI, meanwhile, will end its 15-season run with a reunion-packed two-hour movie (full details here). Additionally, Ted Danson will bring his CSI character, D.B. Russell, over to CSI: Cyber full-time next season.

All told, the CBS schedule looks like this; new shows are in CAPS, click for details.

MONDAY

8 pm The Big Bang Theory

8:30 LIFE IN PIECES (WATCH THE TRAILER)

9 pm Scorpion

10 pm NCIS: LA

MONDAY (after Thursday Night Football concludes in early November)

8 pm SUPERGIRL (WATCH THE TRAILER)

9 pm Scorpion

10 pm NCIS: LA

TUESDAY

8 pm NCIS

9 pm NCIS: New Orleans

10 pm LIMITLESS (WATCH THE TRAILER)

WEDNESDAY

8 pm Survivor

9 pm Criminal Minds

10 pm CODE BLACK (WATCH THE TRAILER)

THURSDAY

8 pm Thursday Night Football

THURSDAY (after football concludes)

8 pm The Big Bang Theory

8:30 pm LIFE IN PIECES (WATCH THE TRAILER)

9 pm Mom

9:30 ANGEL FROM HELL (WATCH THE TRAILER)

10 pm Elementary

FRIDAY

8 pm The Amazing Race

9 pm Hawaii Five-0

10 pm Blue Bloods

SATURDAY

8 pm Crimetime Saturday

9 pm Crimetime Saturday

10 pm 48 Hours

SUNDAY

7 pm 60 Minutes

8 pm Madam Secretary

9 pm The Good Wife

10 pm CSI: Cyber

NOT RETURNING NEXT SEASON: Battle Creek, The McCarthys, The Mentalist, The Millers, Reckless, Stalker and Two and a Half Men.