Alsaady I.

Tedford E.

Alsaad M.

Bristow G.

Kohli S.

Murray M.

Reeves M.

Vijayabaskar M.S.

Clapcote S.J.

Wastling J.

McConkey G.A. Downregulation of the Central Noradrenergic System by Toxoplasma gondii Infection. Infect. Immun. 87 : e00789-18 View in Article Scopus (1)

PubMed

Crossref

Google Scholar

Avants B.B.

Epstein C.L.

Grossman M.

Gee J.C. Symmetric diffeomorphic image registration with cross-correlation: evaluating automated labeling of elderly and neurodegenerative brain. Med. Image Anal. 12 : 26-41 View in Article Scopus (1514)

PubMed

Crossref

Google Scholar

Avants B.B.

Tustison N.J.

Song G.

Cook P.A.

Klein A.

Gee J.C. A reproducible evaluation of ANTs similarity metric performance in brain image registration. Neuroimage. 54 : 2033-2044 View in Article Scopus (1095)

PubMed

Crossref

Google Scholar

Berdoy M.

Webster J.P.

Macdonald D.W. Parasite-altered behaviour: is the effect of Toxoplasma gondii on Rattus norvegicus specific?. Parasitology. 111 : 403-409 View in Article PubMed

Crossref

Google Scholar

Berdoy M.

Webster J.P.

Macdonald D.W. Fatal attraction in rats infected with Toxoplasma gondii. Proc. Biol. Sci. 267 : 1591-1594 View in Article PubMed

Crossref

Google Scholar

Berenreiterová M.

Flegr J.

Kuběna A.A.

Němec P. The distribution of Toxoplasma gondii cysts in the brain of a mouse with latent toxoplasmosis: implications for the behavioral manipulation hypothesis. PLoS One. 6 : e28925 View in Article Scopus (93)

PubMed

Crossref

Google Scholar

Boissier J.R.

Simon P.

Lwoff J.M. [Use of a particular mouse reaction (hole board method) for the study of psychotropic drugs]. Therapie. 19 : 571-583 View in Article PubMed

Google Scholar

Braun L.

Brenier-Pinchart M.P.

Yogavel M.

Curt-Varesano A.

Curt-Bertini R.L.

Hussain T.

Kieffer-Jaquinod S.

Coute Y.

Pelloux H.

Tardieux I.

et al. A Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation. J. Exp. Med. 210 : 2071-2086 View in Article Scopus (101)

PubMed

Crossref

Google Scholar

Braun L.

Brenier-Pinchart M.P.

Hammoudi P.M.

Cannella D.

Kieffer-Jaquinod S.

Vollaire J.

Josserand V.

Touquet B.

Coute Y.

Tardieux I.

et al. The Toxoplasma effector TEEGR promotes parasite persistence by modulating NF-kappaB signalling via EZH2. Nat. Microbiol. 4 : 1208-1220 View in Article Scopus (3)

PubMed

Crossref

Google Scholar

Burgdorf K.S.

Trabjerg B.B.

Pedersen M.G.

Nissen J.

Banasik K.

Pedersen O.B.

Sørensen E.

Nielsen K.R.

Larsen M.H.

Erikstrup C.

et al. Large-scale study of Toxoplasma and Cytomegalovirus shows an association between infection and serious psychiatric disorders. Brain Behav. Immun. 79 : 152-158 View in Article Scopus (13)

PubMed

Crossref

Google Scholar

Chung K.

Wallace J.

Kim S.Y.

Kalyanasundaram S.

Andalman A.S.

Davidson T.J.

Mirzabekov J.J.

Zalocusky K.A.

Mattis J.

Denisin A.K.

et al. Structural and molecular interrogation of intact biological systems. Nature. 497 : 332-337 View in Article Scopus (904)

PubMed

Crossref

Google Scholar

Coffey M.J.

Sleebs B.E.

Uboldi A.D.

Garnham A.

Franco M.

Marino N.D.

Panas M.W.

Ferguson D.J.

Enciso M.

O’Neill M.T.

et al. An aspartyl protease defines a novel pathway for export of Toxoplasma proteins into the host cell. eLife. 4 : e10809 View in Article Scopus (33)

PubMed

Crossref

Google Scholar

Curt-Varesano A.

Braun L.

Ranquet C.

Hakimi M.A.

Bougdour A. The aspartyl protease TgASP5 mediates the export of the Toxoplasma GRA16 and GRA24 effectors into host cells. Cell Microbiol. 18 : 151-167 View in Article Scopus (30)

PubMed

Crossref

Google Scholar

Däubener W.

Remscheid C.

Nockemann S.

Pilz K.

Seghrouchni S.

Mackenzie C.

Hadding U. Anti-parasitic effector mechanisms in human brain tumor cells: role of interferon-gamma and tumor necrosis factor-alpha. Eur. J. Immunol. 26 : 487-492 View in Article Scopus (69)

PubMed

Crossref

Google Scholar

Dellacasa-Lindberg I.

Hitziger N.

Barragan A. Localized recrudescence of Toxoplasma infections in the central nervous system of immunocompromised mice assessed by in vivo bioluminescence imaging. Microbes Infect. 9 : 1291-1298 View in Article Scopus (46)

PubMed

Crossref

Google Scholar

Donald R.G.

Carter D.

Ullman B.

Roos D.S. Insertional tagging, cloning, and expression of the Toxoplasma gondii hypoxanthine-xanthine-guanine phosphoribosyltransferase gene. Use as a selectable marker for stable transformation. J. Biol. Chem. 271 : 14010-14019 View in Article PubMed

Crossref

Google Scholar

Donley D.W.

Olson A.R.

Raisbeck M.F.

Fox J.H.

Gigley J.P. Huntingtons Disease Mice Infected with Toxoplasma gondii Demonstrate Early Kynurenine Pathway Activation, Altered CD8+ T-Cell Responses, and Premature Mortality. PLoS One. 11 : e0162404 View in Article Scopus (9)

PubMed

Crossref

Google Scholar

Dubey J.P.

Ferreira L.R.

Alsaad M.

Verma S.K.

Alves D.A.

Holland G.N.

McConkey G.A. Experimental Toxoplasmosis in Rats Induced Orally with Eleven Strains of Toxoplasma gondii of Seven Genotypes: Tissue Tropism, Tissue Cyst Size, Neural Lesions, Tissue Cyst Rupture without Reactivation, and Ocular Lesions. PLoS One. 11 : e0156255 View in Article Scopus (22)

PubMed

Crossref

Google Scholar

Evans A.K.

Strassmann P.S.

Lee I.P.

Sapolsky R.M. Patterns of Toxoplasma gondii cyst distribution in the forebrain associate with individual variation in predator odor avoidance and anxiety-related behavior in male Long-Evans rats. Brain Behav. Immun. 37 : 122-133 View in Article PubMed

Crossref

Google Scholar

Ferrero D.M.

Lemon J.K.

Fluegge D.

Pashkovski S.L.

Korzan W.J.

Datta S.R.

Spehr M.

Fendt M.

Liberles S.D. Detection and avoidance of a carnivore odor by prey. Proc. Natl. Acad. Sci. USA. 108 : 11235-11240 View in Article Scopus (189)

PubMed

Crossref

Google Scholar

Franco M.

Panas M.W.

Marino N.D.

Lee M.C.

Buchholz K.R.

Kelly F.D.

Bednarski J.J.

Sleckman B.P.

Pourmand N.

Boothroyd J.C. A Novel Secreted Protein, MYR1, Is Central to Toxoplasma’s Manipulation of Host Cells. MBio. 7 : e02231-15 View in Article Scopus (36)

PubMed

Crossref

Google Scholar

Frénal K.

Jacot D.

Hammoudi P.M.

Graindorge A.

Maco B.

Soldati-Favre D. Myosin-dependent cell-cell communication controls synchronicity of division in acute and chronic stages of Toxoplasma gondii. Nat. Commun. 8 : 15710 View in Article Scopus (30)

PubMed

Crossref

Google Scholar

Garfoot A.L.

Cervantes P.W.

Knoll L.J. Transcriptional analysis shows a robust host response to Toxoplasma gondii during early and late chronic infection in both male and female mice. Infect. Immun. 87 ( ) View in Article Scopus (1)

PubMed

Crossref

Google Scholar

Gay G.

Braun L.

Brenier-Pinchart M.P.

Vollaire J.

Josserand V.

Bertini R.L.

Varesano A.

Touquet B.

De Bock P.J.

Coute Y.

et al. Toxoplasma gondii TgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-γ-mediated host defenses. J. Exp. Med. 213 : 1779-1798 View in Article Scopus (38)

PubMed

Crossref

Google Scholar

Gazzinelli R.T.

Hieny S.

Wynn T.A.

Wolf S.

Sher A. Interleukin 12 is required for the T-lymphocyte-independent induction of interferon gamma by an intracellular parasite and induces resistance in T-cell-deficient hosts. Proc. Natl. Acad. Sci. USA. 90 : 6115-6119 View in Article PubMed

Crossref

Google Scholar

Gonzalez L.E.

Rojnik B.

Urrea F.

Urdaneta H.

Petrosino P.

Colasante C.

Pino S.

Hernandez L. Toxoplasma gondii infection lower anxiety as measured in the plus-maze and social interaction tests in rats A behavioral analysis. Behav. Brain Res. 177 : 70-79 View in Article Scopus (50)

PubMed

Crossref

Google Scholar

Hammoudi P.-M.

Soldati-Favre D. Insights into the molecular basis of host behaviour manipulation by Toxoplasma gondii infection. Emerg. Top. Life Sci. 1 : 563-572 View in Article Crossref

Google Scholar

Hammoudi P.M.

Jacot D.

Mueller C.

Di Cristina M.

Dogga S.K.

Marq J.B.

Romano J.

Tosetti N.

Dubrot J.

Emre Y.

et al. Fundamental Roles of the Golgi-Associated Toxoplasma Aspartyl Protease, ASP5, at the Host-Parasite Interface. PLoS Pathog. 11 : e1005211 View in Article Scopus (39)

PubMed

Crossref

Google Scholar

Hammoudi P.M.

Maco B.

Dogga S.K.

Frénal K.

Soldati-Favre D. Toxoplasma gondii TFP1 is an essential transporter family protein critical for microneme maturation and exocytosis. Mol. Microbiol. 109 : 225-244 View in Article Scopus (5)

Crossref

Google Scholar

Hari Dass S.A.

Vyas A. Toxoplasma gondii infection reduces predator aversion in rats through epigenetic modulation in the host medial amygdala. Mol. Ecol. 23 : 6114-6122 View in Article Scopus (60)

PubMed

Crossref

Google Scholar

Haroon F.

Händel U.

Angenstein F.

Goldschmidt J.

Kreutzmann P.

Lison H.

Fischer K.D.

Scheich H.

Wetzel W.

Schlüter D.

Budinger E. Toxoplasma gondii actively inhibits neuronal function in chronically infected mice. PLoS One. 7 : e35516 View in Article Scopus (49)

PubMed

Crossref

Google Scholar

Hermes G.

Ajioka J.W.

Kelly K.A.

Mui E.

Roberts F.

Kasza K.

Mayr T.

Kirisits M.J.

Wollmann R.

Ferguson D.J.

et al. Neurological and behavioral abnormalities, ventricular dilatation, altered cellular functions, inflammation, and neuronal injury in brains of mice due to common, persistent, parasitic infection. J. Neuroinflammation. 5 : 48 View in Article Scopus (107)

PubMed

Crossref

Google Scholar

Ihara F.

Nishimura M.

Muroi Y.

Mahmoud M.E.

Yokoyama N.

Nagamune K.

Nishikawa Y. Toxoplasma gondii Infection in Mice Impairs Long-Term Fear Memory Consolidation through Dysfunction of the Cortex and Amygdala. Infect. Immun. 84 : 2861-2870 View in Article Scopus (12)

PubMed

Crossref

Google Scholar

Ingram W.M.

Goodrich L.M.

Robey E.A.

Eisen M.B. Mice infected with low-virulence strains of Toxoplasma gondii lose their innate aversion to cat urine, even after extensive parasite clearance. PLoS One. 8 : e75246 View in Article Scopus (56)

PubMed

Crossref

Google Scholar

Kannan G.

Moldovan K.

Xiao J.C.

Yolken R.H.

Jones-Brando L.

Pletnikov M.V. Toxoplasma gondii strain-dependent effects on mouse behaviour. Folia Parasitol. (Praha). 57 : 151-155 View in Article PubMed

Crossref

Google Scholar

Konradt C.

Ueno N.

Christian D.A.

Delong J.H.

Pritchard G.H.

Herz J.

Bzik D.J.

Koshy A.A.

McGavern D.B.

Lodoen M.B.

Hunter C.A. Endothelial cells are a replicative niche for entry of Toxoplasma gondii to the central nervous system. Nat. Microbiol. 1 : 16001 View in Article PubMed

Crossref

Google Scholar

Leger M.

Quiedeville A.

Bouet V.

Haelewyn B.

Boulouard M.

Schumann-Bard P.

Freret T. Object recognition test in mice. Nat. Protoc. 8 : 2531-2537 View in Article PubMed

Crossref

Google Scholar

Li H.

Handsaker B.

Wysoker A.

Fennell T.

Ruan J.

Homer N.

Marth G.

Abecasis G.

Durbin R.

1000 Genomes Project Data Processing Subgroup The Sequence alignment/map (SAM) format and SAMtools. Bioinformatics. 25 : 2078-2079 View in Article Scopus (16662)

PubMed

Crossref

Google Scholar

Martynowicz J.

Augusto L.

Wek R.C.

Boehm II, S.L.

Sullivan Jr., W.J. Guanabenz Reverses a Key Behavioral Change Caused by Latent Toxoplasmosis in Mice by Reducing Neuroinflammation. MBio. 10 : e00381-19 View in Article Scopus (1)

PubMed

Crossref

Google Scholar

Parlog A.

Harsan L.A.

Zagrebelsky M.

Weller M.

von Elverfeldt D.

Mawrin C.

Korte M.

Dunay I.R. Chronic murine toxoplasmosis is defined by subtle changes in neuronal connectivity. Dis. Model. Mech. 7 : 459-469 View in Article Scopus (27)

PubMed

Crossref

Google Scholar

Pittman K.J.

Aliota M.T.

Knoll L.J. Dual transcriptional profiling of mice and Toxoplasma gondii during acute and chronic infection. BMC Genomics. 15 : 806 View in Article Scopus (66)

PubMed

Crossref

Google Scholar

R Studio Team RStudio: Integrated Development for R. RStudio , View in Article Google Scholar

Radke J.R.

Guerini M.N.

Jerome M.

White M.W. A change in the premitotic period of the cell cycle is associated with bradyzoite differentiation in Toxoplasma gondii. Mol. Biochem. Parasitol. 131 : 119-127 View in Article Scopus (65)

PubMed

Crossref

Google Scholar

Samuelsen C.L.

Meredith M. The vomeronasal organ is required for the male mouse medial amygdala response to chemical-communication signals, as assessed by immediate early gene expression. Neuroscience. 164 : 1468-1476 View in Article Scopus (29)

PubMed

Crossref

Google Scholar

Shen B.

Brown K.M.

Lee T.D.

Sibley L.D. Efficient gene disruption in diverse strains of Toxoplasma gondii using CRISPR/CAS9. MBio. 5 ( ) View in Article Scopus (173)

Crossref

Google Scholar

Soldati D.

Boothroyd J.C. Transient transfection and expression in the obligate intracellular parasite Toxoplasma gondii. Science. 260 : 349-352 View in Article PubMed

Crossref

Google Scholar

Sugden K.

Moffitt T.E.

Pinto L.

Poulton R.

Williams B.S.

Caspi A. Is Toxoplasma Gondii Infection Related to Brain and Behavior Impairments in Humans? Evidence from a Population-Representative Birth Cohort. PLoS One. 11 : e0148435 View in Article Scopus (51)

PubMed

Crossref

Google Scholar

Sutterland A.L.

Kuin A.

Kuiper B.

van Gool T.

Leboyer M.

Fond G.

de Haan L. Driving us mad: the association of Toxoplasma gondii with suicide attempts and traffic accidents - a systematic review and meta-analysis. Psychol. Med. 49 : 1608-1623 View in Article Scopus (1)

PubMed

Crossref

Google Scholar

Suzuki Y.

Orellana M.A.

Schreiber R.D.

Remington J.S. Interferon-gamma: the major mediator of resistance against Toxoplasma gondii. Science. 240 : 516-518 View in Article PubMed

Crossref

Google Scholar

Torres L.

Robinson S.A.

Kim D.G.

Yan A.

Cleland T.A.

Bynoe M.S. Toxoplasma gondii alters NMDAR signaling and induces signs of Alzheimer’s disease in wild-type, C57BL/6 mice. J. Neuroinflammation. 15 : 57 View in Article Scopus (6)

PubMed

Crossref

Google Scholar

Voigt F.F.

Kirschenbaum D.

Platonova E.

Pagès S.

Campbell R.A.

Kästli R.

Schaettin M.

Egolf L.

Van Der Bourg A.

Bethge P.

et al. The mesoSPIM initiative: open-source light-sheet mesoscopes for imaging in cleared tissue. bioRxiv. https://doi.org/10.1101/577122 View in Article Crossref

Google Scholar

Vyas A.

Kim S.K.

Giacomini N.

Boothroyd J.C.

Sapolsky R.M. Behavioral changes induced by Toxoplasma infection of rodents are highly specific to aversion of cat odors. Proc. Natl. Acad. Sci. USA. 104 : 6442-6447 View in Article Scopus (322)

PubMed

Crossref

Google Scholar

Wang T.

Sun X.

Qin W.

Zhang X.

Wu L.

Li Y.

Zhou C.

Zhou H.

He S.

Cong H. From inflammatory reactions to neurotransmitter changes:Implications for understanding the neurobehavioral changes in mice chronically infected with Toxoplasma gondii. Behav. Brain Res. 359 : 737-748 View in Article Scopus (3)

PubMed

Crossref

Google Scholar

Webster J.P.

Lamberton P.H.

Donnelly C.A.

Torrey E.F. Parasites as causative agents of human affective disorders? The impact of anti-psychotic, mood-stabilizer and anti-parasite medication on Toxoplasma gondii’s ability to alter host behaviour. Proc. Biol. Sci. 273 : 1023-1030 View in Article Scopus (155)

PubMed

Crossref

Google Scholar

Weiner III, J.

Parida S.K.

Maertzdorf J.

Black G.F.

Repsilber D.

Tellar A.

Mohney R.P.

Arndt-Sullivan C.

Ganoza C.A.

Faé K.C.

et al. Biomarkers of Inflammation, Immunosuppression and Stress Are Revealed by Metabolomic Profiling of Tuberculosis Patients. PLoS ONE. 7 : e40221 View in Article Scopus (118)

PubMed

Crossref

Google Scholar

Wickham H. ggplot2: Elegant Graphics for Data Analysis.. Springer-Verlag New York , View in Article Crossref

Google Scholar

Xiao J.

Kannan G.

Jones-Brando L.

Brannock C.

Krasnova I.N.

Cadet J.L.

Pletnikov M.

Yolken R.H. Sex-specific changes in gene expression and behavior induced by chronic Toxoplasma infection in mice. Neuroscience. 206 : 39-48 View in Article Scopus (53)

PubMed

Crossref

Google Scholar