Mike Bloomberg’s new paid meme campaign on Instagram has prompted its owner Facebook to clarify on Friday that influencers must disclose such partnerships — and said the humorous posts may never end up in the social media giant’s political ad database.

Facebook said that influencers also must properly label the “branded content” — sponsored items posted by ordinary users who are typically paid by companies or organizations.

“We’re allowing US-based political candidates to work with creators to run this content, provided the political candidates are authorized and the creators disclose any paid partnerships through our branded content tools,” a Facebook rep told The Post in a statement.

“Branded content is different from advertising, but in either case we believe it’s important people know when they’re seeing paid content on our platforms,” the spokesperson added.

On Wednesday, Bloomberg unleashed a flood of posts on Instagram in a partnership with some of the most-followed accounts in a series of bizarre memes.

The posts pretend to be depicting direct messages from the former New York City mayor himself to the individual accounts.

Most of the posts find him taking the persona of an out-of-touch old guy, trying to reach out to a younger audience in a tongue-in-cheek fashion and go viral.

One depicted him asking an influencer: “Can you make a viral meme to let the younger demographic know I’m the cool candidate?”

The posts — which disclosed sponsorship by Bloomberg’s campaign — won’t have to be archived in Facebook’s ad database unless the influencer pays to promote the post itself. They will still have to disclose the paid partnership.

The ad library publicly catalogs political ads and allows other campaigns, journalists and watchdog groups to view the type of messages pushed by politicians.

In his meme campaign, Bloomberg exploited a loophole to skirt many of the rules that tech companies have imposed on political ads to safeguard American elections from malicious foreign and domestic interference and misinformation.

Until Friday, Facebook tried to keep campaigns from using such branded content by barring them from using a tool designed to help advertisers run such posts on Facebook and Instagram.

“After hearing from multiple campaigns, we agree that there’s a place for branded content in political discussion on our platforms,” Facebook told The Associated Press. “We’re allowing US-based political candidates to work with creators to run this content.”

Politicians still won’t be required to disclose how much they paid the influencers to run the posts – and the new rules won’t apply to someone merely creating or sharing a post about a politician without getting paid.

With Post wires