Around 74% of all deaths in the United States occur as a result of 10 causes. Over the past 5 years, the main causes of death in the U.S. have remained fairly consistent. According to the Centers for Disease Control and Prevention (CDC), there were 2,813,503 registered deaths in the United States in 2017. The age-adjusted death rate, which accounts for the aging population, is 731.9 deaths per 100,000 people in the U.S. This is an increase of 0.4% over 2016’s death rate. However, the CDC advise that using age-adjusted rates is inaccurate for ranking causes of death. All figures and percentages provided here come from the most recent data from the CDC, collected in 2017. In this article, we expand on each of the leading causes of death and provide links to more detailed information on each condition. We also rank the causes according to the number of deaths per condition and their percentage share of the overall registered death count in the U.S.

2. Cancer Deaths in 2017: 599,108

Percentage of total deaths: 21.3% Cancer occurs when cells do not die at the normal point in their life cycle. If a person’s body cannot control the spread of these cells, they can interfere with essential, life-sustaining systems and possibly lead to death. Everyone has some degree of risk, but for most cancers, the risk will increase with age. Some people have a higher or lower risk due to differences in exposure to carcinogens, such as from smoking or exposure to chemical pollutants. Genetic factors also play a strong role in cancer’s development. Race and sex also play a role in a person’s risk of developing cancer, depending on the type. That said, lung cancer causes more deaths than any other cancer in both men and women. However, researchers are always taking steps to advance cancer treatment. In fact, the death rate from all cancers in the U.S. has dropped by 26% since 1991. Estimated cancer-related deaths for 2019 The American Cancer Society estimate how many people will die from certain types of cancer in 2019. According to them, the leading causes of death from cancer for males will be: Lung and bronchus cancer: 76,650 deaths

Prostate cancer: 31,620 deaths

Colorectal cancer: 27,640 deaths The leading causes of death from cancer for females will be: Lung and bronchus cancer: 66,020 deaths

Breast cancer: 41,760 deaths

Colorectal cancer: 23,380 deaths To learn more about cancer, click here.

3. Unintentional injuries Deaths in 2017: 169,936

Percentage of total deaths: 6% Accidents, or unintentional injuries, are the 4th leading cause of death in the U.S. overall, and the leading cause of death for those aged 1–44. Possible prevention measures Accidents are unintentional and usually unavoidable. However, there are many ways to reduce the risk of accidental injury and death. Some key components of accident prevention include focusing on road and workplace safety, such as using a seatbelt and never driving or operating heavy machinery while under the influence of alcohol or drugs.

6. Alzheimer’s disease Deaths in 2017: 121,404

Percentage of total deaths: 4.3% Dementia refers to a group of conditions that cause a decline in cognitive function. This affects a person’s ability to perform everyday activities. Damage to the nerve cells in the brain causes dementia. As a result of the damage, neurons can no longer function normally and may die. This, in turn, can lead to changes in memory, behavior, and the ability to think clearly. Alzheimer’s disease is just one type of dementia. Another type, called vascular dementia, can cause similar symptoms but instead results from changes to blood flow to the brain. For people with Alzheimer’s disease, neuron damage and death eventually impair their ability to perform essential actions, such as walking and swallowing. People in the final stages of this condition may not be able to leave their bed and may require around the clock care. Alzheimer’s is ultimately fatal. In the U.S., an estimated 5.8 million people currently have Alzheimer’s disease, according to the Alzheimer’s Association. This figure may rise to 14 million people by 2050 as life expectancy continues to increase. Alzheimer’s is also the only cause of death in the top 10 that medical experts cannot cure, prevent, or slow down. In this article, learn more about Alzheimer’s disease.

7. Diabetes Deaths in 2017: 83,564

Percentage of total deaths: 3% Diabetes is a condition wherein the body can no longer control blood glucose, which leads to dangerously high levels of blood glucose. This is called hyperglycemia. Persistent hyperglycemia can damage the body’s tissues, including those in the nerves, blood vessels, and eyes. The body converts most of the food people eat into glucose, a simple sugar, which it can then use for energy. The pancreas, an organ near the stomach, makes a hormone called insulin to move glucose from the bloodstream into the cells. There are two main types of diabetes: type 1 diabetes and type 2 diabetes. The bodies of people with type 1 diabetes do not produce insulin at all, so these people need to supplement their supply. The bodies of people with type 2 diabetes cannot use insulin effectively. However, it is possible to control the risk of type 2 diabetes with careful dietary management and regular exercise. Diabetes can cause serious health complications, including heart disease, blindness, kidney failure, and the need for amputation of the lower extremities. Learn more about diabetes, including some of the treatment options, here.

8. Influenza and pneumonia Deaths in 2017: 55,672

Percentage of total deaths: 2% Influenza, or flu, is a highly contagious viral infection. It is one of the most severe illnesses of the winter season. Flu spreads easily from person to person, usually when someone who carries the virus coughs or sneezes. A person can have the flu more than once, as many different strains of the virus can cause infection. They may belong to one of three different influenza families: A, B or C. Type A viruses tend to affect adults more severely, while type B viruses most often cause health problems in children. Type C viruses are fairly uncommon. Pneumonia, a serious condition that causes inflammation of the lungs, can cause complications in people who have the flu. Pneumonia causes the air sacs in the lungs to fill with pus and other fluids, preventing oxygen from reaching the bloodstream. If there is too little oxygen in the blood, the body’s cells cannot function. This can be fatal.