No majority of voters in any of the 632 constituencies in England, Scotland and Wales want their MP to back Theresa May's Brexit deal, according to a fresh polling analysis released just three days before a major parliamentary vote.

It will come as a blow for the prime minister, who issued a plea on Friday for MPs to support her plans as she attempts to seek eleventh-hour concessions from Brussels in the tense negotiations.

On Saturday, the talks descended into open hostility as the cabinet minister Andrea Leadsom accused the EU of playing "games" after a public row between the Brexit secretary, and the bloc's chief negotiator.

The new constituency-by-constituency model based on YouGov polling for the People's Vote campaign of more than 25,000 voters presents grim reading for Downing Street ahead of Tuesday's "meaningful vote" on Ms May's Brexit agreement.

If "don't knows" are excluded from the polling, which was conducted in January, the results add that there is a majority support in just two constituencies in England, Scotland and Wales for the prime minister's deal.

Britain before Brexit: Scotland Show all 11 1 /11 Britain before Brexit: Scotland Britain before Brexit: Scotland Edinburgh A yellow grit box on the Royal Mile, now containing blankets. One set of contents has been replaced by another, but both are used to make the cold weather less dangerous Richard Morgan/The Independent Britain before Brexit: Scotland Glasgow Students hand feed pigeons, taking time out to feed the birds. And like the lady from Mary Poppins, they too seem proud that they’ve paid the animals attention, happily surrounded by their hunger Richard Morgan/The Independent Britain before Brexit: Scotland Aberdeen A colour-coded stereotype on Union Street, complimenting double yellow lines Richard Morgan/The Independent Britain before Brexit: Scotland Glasgow Two images of man across time: one majestic and colossal; the other distracted and unremarkable. Both are burdened, it seems Richard Morgan/The Independent Britain before Brexit: Scotland Dundee A view of the £80m V&A museum, built on the bank of the River Tay. It’s a controversial addition to the city, providing art and culture and tourism, but not social infrastructure Richard Morgan/The Independent Britain before Brexit: Scotland Inverness The facade of a ‘conspiracy shop’, existing not to make money, but to awaken people from the web of lies in which we supposedly live, to shatter the illusion of reality, to tell the truth Richard Morgan/The Independent Britain before Brexit: Scotland Aberdeen An anonymous act of political expression in modern Britain, adding to the mix, becoming part of the everyday experience of waiting for the green light Richard Morgan/The Independent Britain before Brexit: Scotland Edinburgh Edinburgh’s skyline, overgrown by the skeletal branches of a wintry tree, in which a thrown traffic cone sits entangled and trapped Richard Morgan/The Independent Britain before Brexit: Scotland Glasgow American Christians take it in turns to preach on Buchanan Street. They talk of sin and vulgarity and death and power. It’s an intriguing performance, one framed and mocked by the sex-selling adverts behind Richard Morgan/The Independent Britain before Brexit: Scotland Dundee A Polish football hooligan sticker re-frames the view of the city from the Dundee Law, bringing a foreign presence to the frame, a new look created by the movement of people Richard Morgan/The Independent Britain before Brexit: Scotland Edinburgh Vegan protesters write their ethics on the pavement in chalk, trying to catch the eye of head-down city strollers. Their political graffiti washes away in the night rain Richard Morgan/The Independent

It suggests that even in Ms May's own parliamentary constituency of Maidenhead, voters are opposed to her deal passing in the Commons by 53 per cent to 47 per cent.

The research also claims that if Labour fails to oppose Ms May's deal, the party could suffer at the next general election, with the Conservatives winning a 200-seat majority.

But Jeremy Corbyn has already committed his party to opposing the prime minister's current deal. "We will not be supporting her deal next Tuesday," he said last week.

"We will be voting to take no deal off the table and we will once again be putting our proposals - our five pillars - which are a customs union, market access and protection of rights in this country that have been obtained through the EU," he added.

Peter Kellner, the former president of the pollster YouGov, said: "The coalition that produced a narrow majority for Brexit three years ago is falling apart."

He continued: "It brought together traditionalists in Conservative Britain who saw the EU as a threat to British values and sovereignty, with families in Labour's heartlands who felt that 'Brussels' threatened their living standards and their children's job prospects.

"The prime minister's plan is unpopular essentially because few people in either group think it tackles the threat they face.

"The fact that only two constituencies in the entire country (not including her own) want their MP to support her deal shows just how risky it would be for the prime minister to force this deal on the people now."

The findings also came as Brandon Lewis, the chairman of the Conservative Party, urged MPs to back the prime minister's deal during Tuesday's crunch vote.

Speaking to BBC Radio 4's Today programme, Mr Lewis said discussions with the EU would be continuing over the weekend and the government would not accept anything which "compromises the unity of the United Kingdom".

He added: "Parliamentarians have a really, really vital decision to make. The EU and the EU Commission do as well. We have this vote on Tuesday. We need to win that vote.