These jurors have reasonable doubt … that they’re going to make their vacation.

After just two days of deliberations, the men and women weighing evidence in a high-profile NYPD bribery trial in Manhattan are complaining that they want to quit because the two-month trial dragged on too long.

One female juror in the trial of ex-NYPD Deputy Inspector James Grant and Mayor de Blasio donor Jeremy Reichberg on Thursday asked a judge to let her off the case so she can return to her job.

She argued the federal court trial — which ran Nov. 6 to Dec. 21 as prosecutors sought to prove that Reichberg bribed high-ranking cops, including Grant, with lavish gifts such as hookers and weekend getaways — went on a week longer than jurors were told it would.

“I’m sorry, I just — this is taking a big toll on me,” the juror told Manhattan federal judge Gregory Woods during a sidebar, explaining that she’d been trying to do her job from home in her spare time after court.

“I [have] to work … I want to stay, but the anxiety is really getting to me.”

Woods thanked her for her sacrifice but said, “I would ask that you would try to stay.”

The juror responded, “I can only give it another week, hopefully we can come to a conclusion.”

A second female juror also told the judge Thursday that she couldn’t stay past Jan. 4 — because it would interfere with her vacation plans.

Outside of the jurors’ presence, Woods said of the trip, “We will address that issue as it becomes necessary, which is increasingly likely as the lawyers take up to two hours to look up the transcript.”

The antsy jurors can be replaced by alternates if they split early — but the rest of the jurors will then have to start deliberating again from scratch.

Earlier Thursday, the panel of 12 requested parts of the trial transcript, which they received about an hour before being released for the long holiday weekend.

They won’t be back until Jan. 2.