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James Pearce - 'You can't throw Clyne in for a game of this magnitude'

Injuries have severely depleted Jurgen Klopp’s squad but he’s still able to field nearly a first choice line up.

The big miss is going to be Emre Can, who was excellent in the win over City in January.

Defensively, the only decision is at right-back. I’d stick with Trent Alexander-Arnold, I think he’s got the temperament to handle the occasion. I don’t think you can throw Nathaniel Clyne in for a game of this magnitude having not played for nearly a year.

The front three pick themselves but the midfield is a tricky one. Jordan Henderson is nailed on to start so it’s two out of James Milner, Gini Wijnaldum and Alex Oxlade-Chamberlain to join him.

I’d go for Milner and Oxlade-Chamberlain, who caused City plenty of problems on their last visit.

My team (4-3-3): Karius, Alexander-Arnold, Lovren, Van Dijk, Robertson, Henderson, Milner, Oxlade-Chamberlain, Salah, Firmino, Mane.

Ian Doyle - 'Oxlade-Chamberlain in over Gini Wijnaldum'

Let’s get the obvious out of the way first.

Loris Karius is in goal. Virgil van Dijk is one of the centre-backs. Andy Robertson is left-back. Mohamed Salah, Roberto Firmino and Sadio Mane will start up top.

Now to deal with the other things.

First up, Van Dijk’s defensive partner. Joel Matip is out for the season so Dejan Lovren has to start. Here's hoping he avoids making that trademark big blunder.

At right-back, I’m sorely tempted to go with James Milner. However, Trent Alexander-Arnold deserves the chance to prove his worth.

Then there’s the midfield. Emre Can isn’t going to be fit enough to start. Liverpool need plenty of physicality in the engine room, and that makes it easy to go with Milner and Jordan Henderson.

And I’d go with Alex Oxlade-Chamberlain for the other spot. Gini Wijnaldum’s recent illness and poor form sees him miss out.

My team (4-3-3): Karius; Alexander-Arnold, Lovren, Van Dijk, Robertson; Henderson, Milner, Oxlade-Chamberlain; Salah, Mane, Firmino.

Joe Rimmer - 'Liverpool function better with Henderson in the team'

Liverpool. Manchester City. Anfield. Champions League quarter-finals.

Bottle will be needed in the gallons. Nerves icier than a winter’s day in the North Pole.

So which 11 brave souls does Jurgen Klopp plump for?

Well, at least seven of those players pick themselves.

In goal, Loris Karius is now an automatic starter. As are three of the back four, step forward Andy Robertson, Virgil van Dijk and Dejan Lovren.

The front three are the front three.

Elsewhere, I’ll plump for Trent Alexander-Arnold over Nathaniel Clyne. This is no time to start your first game of the season.

Now for the midfield..

The skipper plays. Liverpool function better with Henderson in the team, so he gets the nod.

Then it’s James Milner, Alex Oxlade-Chamberlain and Gini Wijnaldum for two more spots.

For me, it’s the latter who misses out. Chamberlain was just so good in the 4-3 and Milner’s experience against his former club could be vital.

There’s your XI. Now go out and do the business. Make us dream.

My team (4-3-3): Karius; Alexander-Arnold, Lovren, Van Dijk, Robertson; Henderson, Milner, Oxlade-Chamberlain; Salah, Mane, Firmino.

Kristian Walsh - 'What actually is Liverpool's full strength side?'

So, this is it. The big one. Nothing but full-strength will do.

The question is: what actually is Liverpool’s full strength side?

There’s no doubt about the goalkeeper or the front three. There’s also little doubt, in my mind, about the back four. Robertson and Van Dijk are mainstays, now. Lovren is the better partner for the Dutchman. Alexander-Arnold plays, as throwing Clyne into this game for his first start since May would be far too risky.

It’s the midfield where the dilemma lies, and has done for most of the campaign. If Can is fit, then his physicality will be welcome, but will he be 100%? If not, then he cannot start.

Oxlade-Chamberlain is a starter after his performance against this side in January, and he thrives in these sort of high-intensity fixtures. He’ll be joined by the captain and the ex-City man.

Milner was very good against Palace and will help protect Alexander-Arnold down the right-hand side. Henderson will help with the high press and tempo on a night like this.

My team (4-3-3): Karius; Alexander-Arnold, Lovren, Van Dijk, Robertson; Henderson, Milner, Oxlade-Chamberlain; Salah, Mane, Firmino.