Police are reviewing security camera footage in the hunt for two men who committed a savage rape in Brisbane's West End on Friday night.

A 20-year-old woman was attacked after leaving a private function at the Uber nightclub.

Police say she was forced into an alley off Melbourne Street and sexually assaulted.

Police Inspector Rod Kemp says the woman is still in hospital with shocking injuries.

"She was most aggressively raped in the worst way that I have seen in my service," he said.

"The complainant has extensive internal and external injuries."

He says the vicious and planned nature of the attack makes police suspect the pair have carried out similar rapes before.

"It seemed so well orchestrated and the violence they used - animals don't do that to each other," he said.

Inspector Kemp says the victim will remain anonymous.

"I think she needs the respect that we don't identify who she is, only to say that she's a very respectable person in our community," he said.

"She's got a very good career ahead of her. I wouldn't like to say who she is out of respect to her."

Inspector Kemp said the woman had not done anything to put herself in any danger.

"All I can say is this person did the right thing as far as I'm concerned, she stuck to the main drag as she walked down to catch the bus, but unfortunately this happened so it shows you've got to be very wary of your own safety," he said.

Police are appealing for public help to find the two men.

Anyone with information can call Crime Stoppers on 1800 333 000 or visit crimestoppers.com.au.