A: Having been in this industry for 25 years, I would say the one thing we know is our portfolio is going to change every decade because our patents are going to run out. The research part of our model is very important. And I think that as you get more companies coming in who don't have that same model and looking to be a bit more opportunistic and a bit more short term in their vision, it meets the needs of shareholders, but I'm not sure it meets the needs of our industry over the long term. You're talking to someone who works for a 234-year-old company. One of the things I like about Takeda is that it cares just as much about the next decade as the next quarter and will make decisions accordingly. I worry about anything that jeopardizes that R&D model for us.