Thousands of Palestinians in the West Bank and Jerusalem march in solidarity with Gaza, in the largest such protest in years. At least two were killed.

At least two protesters were killed and more than 100 wounded in clashes with Israeli security forces in the West Bank and East Jerusalem late Thursday night, as thousands of Palestinians marched from Ramallah to the Qalandia checkpoint, which separates Jerusalem and the West Bank.

The protest, against Israel’s assault on the Gaza Strip, was the largest the West Bank has seen in years – according to some Palestinian demonstrators, the largest in decades. As of Thursday night, 805 Palestinians had been killed in Gaza since Israel launched its offensive on July 8.

The West Bank march quickly spread to East Jerusalem, where police were said to be clashing with protesters in the Old City, Silwan, and other neighborhoods. Protests were also reported in Nablus and Bethlehem.

Thousands of Palestinians march from Ramallah to Jerusalem. Largest protest in decades. #48KMarch via @Ramideramallah pic.twitter.com/mSakFVfxQv — Hana Khalil (@hkhalil91) July 24, 2014

According to Haaretz reporter Amira Hass, Palestinian ambulances, blaring their horns, were streaming in the opposite direction of the march, evacuating protesters wounded by Israeli fire at the checkpoint.

The West Bank protest came during Laylat al-Qadr, the 27th night of Ramadan and the holiest night of the year for Muslims. According to the Jerusalem Post, Israel Police Micky Rosenfeld said that hundreds of officers would be stationed around the Old City during Friday prayers, and that no Arabs under 50 would be permitted to enter Damascus Gate.

The west bank now…people have had enough and have nothing to lose pic.twitter.com/BcIKm77U7p — Tahanie Aboushi (@Its_T_time06) July 24, 2014

Earlier Thursday, Hamas political bureau head Khaled Meshaal said Hamas was prepared to sign a ceasefire agreement with Israel, as long as Israel’s siege of Gaza is lifted. In comments made from Qatar, Meshaal underlined that he also wants Gaza’s border with Egypt to be opened.