Darren Woodson says the Chiefs will "put big numbers up" at home, but Tedy Bruschi sees the Colts winning in their playoff game. (1:10)

INDIANAPOLIS -- Quarterback Andrew Luck's seven-year NFL résumé features 21 come-from-behind victories when trailing in the fourth quarter and overtime.

But there's one come-from-behind victory that most refer to when it comes to Luck.

It happened Jan. 4, 2014, at Lucas Oil Stadium.

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Indianapolis Colts vs. Kansas City Chiefs in the AFC wild-card playoffs.

The Colts fell behind 38-10 some 76 seconds into the third quarter before Luck did the near-impossible: He led them to a 45-44 victory -- the NFL's second-largest postseason comeback victory -- by throwing for 443 yards and four touchdowns.

As the Colts prepped for Saturday's game in Kansas City (4:35 p.m. ET, NBC) in the AFC divisional playoffs, Luck was asked about the rally.

"There are some really good memories from that game," he said this week. "There are also some not-so-good memories from that game. We dug ourselves quite the hole."

That's just Luck being Luck, not wanting to praise himself. What he did that Saturday night more than five years ago was, as long-snapper Matt Overton said at the time, "an ESPN Instant Classic."

There are two poster-sized Sports Illustrated covers of Luck diving in for a touchdown hanging on the wall in the office of the team's media-relations department.

"The quarterback played his tail off," former Colts coach Chuck Pagano told ESPN this week. "You always have faith and belief, and Andrew gives you hope. Any time you trot him out there, your team has hope. I know it was an entire team deal, but he gives you hope."

From bad to worse

NFL's Biggest Postseason Comebacks The four largest deficits overcome by the winning team in NFL postseason history: Season Round Final Biggest Deficit 1992 Wild card Bills 41, Oilers 38 Trailed 35-3 (third quarter) 2013 Wild card Colts 45, Chiefs 44 Trailed 38-10 (third quarter) 2016 Super Bowl Patriots 34, Falcons 28 (OT) Trailed 28-3 (third quarter) 2002 Wild card 49ers 39, Giants 38 Trailed 38-14 (third quarter)

Pagano, according to tight end Dwayne Allen, tried to get his players motivated by yelling and cursing at them at halftime, when the Colts were trailing 31-10.

It didn't work.

The Colts got the ball to open the second half, but their very first play of the third quarter was Luck's second of three interceptions. The Chiefs scored three plays later to take the 38-10 lead.

"I gave one of those 'win one for the Gipper' speeches and then go out and do that," Pagano said. "Throw in the interception, and then the next thing you know we're down 28 points. Amazing.

"I remember telling the guys there's not a play you can score 28 points on. It's impossible. One play at a time, same mantra. We just needed to catch a break here or there, and we did."

Getting some momentum

Andrew Luck threw for 443 yards and four touchdowns in the second-biggest comeback victory in NFL postseason history. AP Photo/Michael Conroy

The Colts got something going when they responded to Kansas City's score with a 10-yard Donald Brown touchdown. But things started to change in their favor when Colts pass-rusher Robert Mathis had one of his patented strip-sacks on Chiefs quarterback Alex Smith. It gave the Colts the ball at their own 46-yard line.

"You always remember Robert Mathis' strip-sacks because you grew up hearing about them, and then you get to see them live and it helps you," Luck said. "I remember that being pretty cool."

The Colts made it a 38-24 game five plays later on another Brown touchdown.

They knew it

It was like it was meant to be for the Colts when Brown fumbled early in the fourth quarter, the ball bounced off center Samson Satele's helmet and Luck grabbed it and dove into the end zone from 5 yards out to cut the Chiefs' lead to 41-38.

"I remember turning around and seeing the ball on the ground and going 'Oh s---!' and Andrew grabs it and dives in," left tackle Anthony Castonzo said.

Momentum was in the Colts' favor then.

"Hop, skip and jump into the end zone and he scores," Pagano said about Luck. "Just crazy. Once that starts to happen and that momentum switches, anything can happen. I think that's where we finally caught a break and made a couple of plays. The strip-sack, that momentum and all that stuff, you just feel it on the sideline, and you're like, 'This is going to happen, we're going to get this thing done.'"

Just run deep

T.Y. Hilton's 64-yard touchdown catch was the winner for the Colts against the Chiefs during their 2013 playoff game. John Sleezer/Kansas City Star/MCT via Getty Images

The Colts were in the huddle, down 44-38, when Luck told T.Y. Hilton, who had 13 catches for 224 yards, to just "run."

And that's what Hilton did, as he got behind Kansas City's defense for a 64-yard touchdown pass with 4:21 remaining that ended up being the winning score.

"He launched it and I went and got it," Hilton said. "It was fun. It was special. We just never gave up, never gave in. It was a tough game. It was pretty much down the whole game and then towards the end, we just found a way to get a dub."

Pagano couldn't breathe easy until Smith's final pass attempt to receiver Dwayne Bowe, who had eight catches for 150 yards, fell incomplete on fourth down.

"You couldn't relax, especially with the game Bowe had," Pagano said. "I just remember that feeling when it was out of bounds, incomplete and it was over. Everybody was spent. Emotionally, physically."

After the game

Former Colts coach Chuck Pagano on erasing a 38-10 deficit to beat the Chiefs: "Just crazy. Once that starts to happen and that momentum switches, anything can happen." Andy Lyons/Getty Images

There wasn't much to be excited about in Kansas City's locker room.

"A lot of disappointment and shock," Chiefs defensive lineman Allen Bailey said. "We had a 20-something-point lead. People were upset, angry, what happened. How it happened."

Not surprisingly, the Colts' locker room was a madhouse after the game. Players ran around celebrating, and some mocked the media for thinking the game was over when they fell behind 38-10 early in the third quarter.

"As individuals you can do amazing things, but as a team you can make miracles happen," Pagano said. "We made a miracle that day with the second-largest comeback in the history of the National Football League. It's really what we based our whole culture and foundation [on] was that process. It just solidified everything we were about and just again, you love those moments. Spending that time together after an amazing comeback like that."

ESPN Kansas City Chiefs reporter Adam Teicher contributed.