For many, Trump's decision on Tuesday to pull out of the landmark nuclear deal marked the final death knell for the hope created when it was signed in 2015 that Iran might finally escape decades of isolation and US hostility.

" against their government, she said: "That makes them even more angry."

Asked how she felt about Trump's claim that he stood with "the long-suffering Iranian people

"It makes people angry. Sanctions impact the people, not the regime. People worry it will be even more difficult to find medicine when they are sick. This was an issue in the past," said one young woman in Tehran.

Iranians reacted with a mix of sadness, resignation and defiance on Wednesday to US President Donald Trump's withdrawal from the nuclear deal, with sharp divisions among officials on how best to respond.

"The first feeling I got, my family and I, was that we should not stay here anymore," said Katayoon Soltani, an accountant.

"Even without sanctions, our economy was terrible. With this decision, I don't know what will happen. All my friends want to leave Iran. This is not a place where we want to stay," she said.

Counting on Europe

Still hoping to salvage something from the deal, President Hassan Rouhani has instructed his foreign minister Mohammad Javad Zarif to hold negotiations with the other five parties -- Britain, France, Germany, China and Russia.

They have all signalled their consternation at Trump's withdrawal, which includes an order for foreign businesses to wind down their Iranian operations within six months or face US penalties.

(photo by: HO/s Website/AFP)

But while European leaders have defiantly said they will work to protect their trade ties, Iran's leaders are sceptical.

"You want to continue the nuclear deal with the three European countries; I don't have confidence in these three countries," said supreme leader Ayatollah Ali Khamenei in a televised speech.

"If you don't succeed in obtaining a definitive guarantee -- and I really doubt that you can -- at that moment, we cannot continue like this," he said.

Parliament speaker Ali Larijani said Europe had caved to US pressure before, having shut up shop under previous international sanctions in 2012-15.

"We can't put much confidence in their statements about preserving the agreement, but it's worth testing for a few weeks so that it's clear to the world that Iran has tried all the avenues to a peaceful p

olitical resolution," Larijani told parliament.

Military welcomes withdrawal

For many conservatives in Iran, Trump's decision was a vindication.

"I welcome the withdrawal of the United States from the nuclear deal," said General Mohammad Ali Jafari, head of the elite Revolutionary Guards, in several media.

"It was clear from the start that the United States is not trustworthy."

An Iranian man reads a newspaper in Tehran on May 9, 2018 a day after US President Donald Trump announced the US is pulling out of the nuclear deal (photo by: ATTA KENARE/AFP)

He said the nuclear question was just a pretext to curb Iran's defensive capabilities and the "power and influence of the Islamic revolution in the region."

The divisions were clear in the Iranian press on Wednesday morning.

Reformist daily Etemad welcomed a "nuclear deal without the trouble-maker" and reprinted a tweet from Rouhani saying: "We have been freed from the evil of someone who does not respect their commitments."

The ultra-hardline Kayhan, on the other hand, opted for: "Trump has torn up the nuclear deal, it is time for us to burn it".

Some hardline lawmakers demonstrated their feelings on the floor of the parliament chamber by burning a paper American flag and a copy of the nuclear accord.

'Enrichment without limit'

Seeking to show that he was not taking Trump's announcement lying down, Rouhani said he had ordered Iran's Atomic Energy Organisation to prepare to resume uranium enrichment "without limit".

"We will wait several weeks before applying this decision. We will speak with our friends and allies, the other members of the nuclear agreement," he said in his televised speech immediately after Trump's announcement.

former US embassy in the Iranian capital Tehran on May 8, 2018 (photo by: ATTA KENARE/AFP)

Larijani warned that Trump only understood the "language of force" and that, if the negotiations with the other parties failed, Iran would have to use its nuclear programme to force the world "to see reason".

On the streets, some were proudly defiant.

"I was asleep when Trump made his speech. It's not important to us, we don't care. We are Iranian and we have our way and we don't care about Trump's actions," said bus driver Ali Bigdeli.

One businessman in Iran said the renewed sanctions would certainly add to Iran's economic woes, but could never be as bad as the previous period under Barack Obama.

"The Iranian people are tired from all the pressure but the new sanctions cannot be worse than last time, because now the Europeans are not on America's side and neither are the Asians," said Mohammad Reza Behzadian, former head of Tehran's chamber of commerce.