Nashville Predators captain Shea Weber will miss the remainder of the Western Conference First Round series against the Chicago Blackhawks because of a lower-body injury, the Predators announced Friday.

Weber was injured in Game 2 on a hit by Chicago forward Brandon Saad at 9:20 of the second period. Weber appeared unable to put any weight on his right leg as he left the ice. He did not travel to Chicago for Games 3 and 4, and did not play in Game 5.

The Predators trail the best-of-7 series 3-2 with Game 6 on Saturday at United Center in Chicago (8 p.m. ET; NBC, SN, TVA Sports 2).

Veteran center Mike Fisher assisted on one of Filip Forsberg's three goals in a 5-2 Game 5 win after missing three games because of a lower-body injury. He also won half his faceoffs in nearly 15 minutes of ice time as the Predators avoided elimination.

"Big boost. He's definitely one of our leaders on our team and I think it showed the way he played [Thursday]," defenseman Roman Josi said of Fisher. "He's such a big presence out there. He's physical and he gets on the forecheck and just makes it so much harder on the other team. … To have a guy like him back, it's definitely huge for us."

Fisher missed the beginning of the regular season recovering from an Achilles injury, but he returned to get 19 goals and 39 points in 59 regular-season games. He played 5:32 in Game 1 before sustaining the lower-body injury.

"It felt great," Fisher said. "It's never fun sitting out, especially in playoffs, and I couldn't wait to get back. I felt better than I thought I would, which is a good sign. That was a fun game, a huge win for us as we all know. But we're back to business tomorrow in the same situation. We haven't won anything yet. It's one game; we've got to build on it."

Fisher has extensive Stanley Cup Playoff experience, making it to the Eastern Conference Final in 2003 and Stanley Cup Final in 2007 as a member of the Ottawa Senators. He will play in his 100th postseason game Saturday.

"I think all year we've done a good job of responding," Fisher said. "When we needed wins we've shown up. That's what we've got to continue to do. We need another game like that tomorrow where it's everything we've got, everything on the ice as a team, just executing the right plays. This is what we work for all year long, for these situations."

Predators coach Peter Laviolette said they have kept an even keel throughout the regular season and playoffs regardless of the circumstances.

"We lose [Game 1] in triple overtime and the guys came back from that [a 6-2 win in Game 2]," Laviolette said. "We won [Thursday]. … We can only focus on the positives and what we can control. I just think there's a confidence with the group; I don't necessarily know if it has to do with wins and losses."