BOSTON - Xander Bogaerts was a late scratch from Tuesday's lineup, with Deven Marrero replacing him at short and Brock Holt stepping in at third base.

Manager John Farrell suggested a lineup shuffle would be coming with Boston's offense struggling. Bogaerts has been one of the players scuffling, hitting .213/.294/.320 over his last 20 games.

Among the biggest changes in the lineup include Hanley Ramirez playing first base for just the second time this season. Chris Young is slotted in as the designated hitter against Blue Jays lefty J.A. Happ.

Ramirez has been hampered by sore shoulders that prevented him from playing first for a majority of the season. He logged his first start on May 10 in Milwaukee and then started at first again on June 14 in Philly.

The Red Sox sent first baseman Sam Travis to Triple-Pawtucket earlier in the day among a series of moves making Ramirez's start at first base more interesting.

Meanwhile, Mookie Betts remains in the leadoff spot, but Andrew Benintendi has been moved up to the two-hole with Dustin Pedroia to the three-spot.

Brian Johnson was called up on Tuesday to make the start, which originally had been slated for Doug Foster. Fister, though, made 53 pitches in relief in Saturday's 16-inning affair preventing him from making the start Tuesday.

RED SOX

Mookie Betts RF

Andrew Benintendi LF

Dustin Pedroia 2B

Hanley Ramirez 1B

Chris Young DH

Jackie Bradley Jr. CF

Sandy Leon C

Deven Marrero SS

Brock Holt 3B

Brian Johnson LHP

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