Major changes are proposed for a cycling black spot in inner-city Brisbane where 27 riders have been injured in the past five years.

Those accidents included a serious incident in August 2017, in which five cyclists were hospitalised, on the popular cycling drive along Dornoch Terrace at West End.

Five people were taken to hospital after this accident in 2017.

Dornoch Terrace is one section of a city cycling loop running from the University of Queensland, across the Eleanor Schonell Bridge, up Gladstone Road, along Dornoch Terrace, around the Brisbane River at Toowong and back to the university.

Brisbane City Council proposes removing 115 car spaces, installing traffic lights, changing bus stations, building pedestrian refuges and reducing the speed in one specific zone along Dornoch Terrace near shops and restaurants to make the 1.2-kilometre stretch of road safer.