House Speaker Nancy Pelosi Nancy PelosiAs families deal with coronavirus, new federal dollars should follow the student Sunday shows - Ruth Bader Ginsburg's death dominates Hypocrisy rules on both sides over replacing Justice Ginsburg MORE (D-Calif.) on Wednesday said she would be comfortable with Sen. Bernie Sanders Bernie SandersNYT editorial board remembers Ginsburg: She 'will forever have two legacies' Two GOP governors urge Republicans to hold off on Supreme Court nominee Sanders knocks McConnell: He's going against Ginsburg's 'dying wishes' MORE (I-Vt.) as the Democratic presidential nominee in November.

The congresswoman was asked the question as she was leaving a closed-door meeting in the House basement Wednesday morning.

She replied with one word: "Yes."

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Other congressional Democrats have balked at the idea of Sanders, a longtime independent and self-proclaimed democratic socialist, being the party's nominee in the general election.

Senate Minority Leader Charles Schumer Chuck SchumerRepublican senator says plans to confirm justice before election 'completely consistent with the precedent' Video of Lindsey Graham arguing against nominating a Supreme Court justice in an election year goes viral Graham signals support for confirming a Supreme Court nominee this year MORE (D-N.Y.) on Tuesday also suggested that he would be comfortable with the Vermont senator as his party's nominee.

"Look, the bottom line is very simple," Schumer said Tuesday when asked about Sanders's praise of former Cuban leader Fidel Castro's literacy program.

"We have a lot of strong nominees. ... I'm not supporting one over the other, but I think every one of them will beat President Trump Donald John TrumpBiden leads Trump by 36 points nationally among Latinos: poll Trump dismisses climate change role in fires, says Newsom needs to manage forest better Jimmy Kimmel hits Trump for rallies while hosting Emmy Awards MORE," he said.

Sanders has surged to front-runner status after virtually tying for first in Iowa and winning New Hampshire and Nevada outright.

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The Vermont Independent has also cut into former Vice President Joe Biden Joe BidenBiden leads Trump by 36 points nationally among Latinos: poll GOP set to release controversial Biden report Can Donald Trump maintain new momentum until this November? MORE's once-sizable lead in South Carolina, which is seen as a bellwether primary state with its large African American population.

In the latest NBC News-Marist poll, Biden held a 27 percent-23 percent lead over Sanders in South Carolina.

Biden's candidacy could see new momentum after receiving the significant endorsement of House Majority Whip James Clyburn (D-S.C.) on Wednesday morning. Clyburn is the highest-ranking black congressional lawmaker and Biden has held a firm lead on support from black voters. Nearly a third of South Carolina's population is black.