Firefighters battled a blaze in Manhattan Sunday morning that sent smoke billowing from the top of the 12-story Midtown building.

The fire at 145 W. 45th Street started around 7:45 a.m. in the ductwork of the building, according to the FDNY.

Videos posted to social media show a plume of smoke billowing from the roof of the office building.

One person was taken to NYU Hospital for trouble breathing and two others were treated on scene, fire officials said.

The fire forced guests at the Hyatt next door to evacuate, according to officials.

The fire was under control at about 8:50 a.m., and the hotel guests were being let back in the building, an FDNY spokesman said.