Ajayi, who earned AFC Offensive Player of the Week honors after running roughshod over the Bills for a second time, also tends to get stronger later in games, as evidenced by his 6.1 yard-per-carry average in the fourth quarter. His three longest runs this season (62, 57 and 53 yards) all came in the fourth quarter or overtime.

“(The Dolphins) are the best running team we’ve faced so far,” Patriots defensive end Chris Long said Wednesday. “So it will be a great test.”

THE QUARTERBACK

Ryan Tannehill will be watching Sunday’s game from the sideline as he continues to recover from a sprained knee. Starting in his place will be veteran backup Matt Moore, who has guided Miami to two consecutive wins since replacing his injured comrade.

The 32-year-old Moore did not start a single game over the previous four seasons, but the drop-off from Tannehill to him really is not all that significant. Tannehill has yet to live up to his billing as a top-10 pick, and Moore, who lacks some of Tannehill’s athleticism but still can be mobile in the pocket, has played well since taking over, throwing six touchdown passes with two interceptions and posting a 113.4 passer rating.

Moore’s last game against the Patriots came in 2011. He completed 16 of 32 passes for 281 yards and three touchdowns with one interception in a 27-24 Dolphins loss.

“He’s started and led that football team,” Patriots safety Devin McCourty said. “I would imagine that that team has tremendous trust in him.”

THE SECONDARY

The Dolphins could be without three of their four starting defensive backs for Sunday’s game. They’ll definitely be missing at least two, as safeties Reshad Jones and Isa Abdul-Quddus both are on injured reserved. Cornerback Byron Maxwell also could be unavailable as he nurses an ankle injury.

Defending an offense as explosive as the Patriots’ with a crew of backups in the secondary will be a tall order for Miami. New England, fresh off a 41-3 beatdown of the New York Jets, has scored 30 or more points in two of its last three games and hasn’t lost since Week 10.

THE VENUE

The Patriots have owned the Dolphins in Foxboro in recent years, but their traditional struggles in South Florida have persisted. Bill Belichick’s troops have lost three straight games at the venue now known as Hard Rock Stadium, including an ugly 20-10 defeat in Week 17 last season that cost them home-field advantage.

“I think for us, this is a really tough test,” McCourty said. “We haven’t won there in three years. … And not winning shows we just haven’t played well down there.”

THE STAKES

New England can clinch the AFC’s No. 1 playoff seed with a win or a tie over Miami or an Oakland Raiders loss or tie. The Dolphins, meanwhile, are hoping to nab the No. 5 seed, which would mean a trip to Houston in the wild-card round rather than one to Pittsburgh. To do so, they’ll need to beat the Patriots and have the Kansas City Chiefs lose to the San Diego Chargers.

Miami has won nine of its last 10 games, but only one of those wins — a Week 6 victory over the Steelers — came against a team that will qualify for the playoffs this season.

Thumbnail photo via Tommy Gilligan/USA TODAY Sports Images