MPs have called Theresa May “irresponsible”, “disgraceful” and “toxic” after she blamed them for for the UK’s impending failure to leave the EU on 29 March.

Labour’s Wes Streeting accused the prime minister of putting MPs’ lives in danger with an “incendiary” address.

Ms May used a Downing Street speech to criticise the very people she needs to get her Brexit deal through the Commons at the third time of asking, telling voters that she was “sure” that “you, the public, have had enough” of political games.

She said: “You’re tired of the infighting, you’re tired of the political games and the arcane procedural rows, tired of MPs talking about nothing else but Brexit when you have real concerns about our children’s schools, our National Health Service, knife crime.

“You want this stage of the Brexit process to be over and done with. I agree. I am on your side.”

Tariffs in the event of a no-deal Brexit Show all 15 1 /15 Tariffs in the event of a no-deal Brexit Tariffs in the event of a no-deal Brexit Pork There will be tariffs on pork in order to protect British farmers Getty Tariffs in the event of a no-deal Brexit Cheese There will be tariffs in place on some cheeses including €22.10/100kg of cheddar, €19.10/100kg of processed cheese and €18.60/100kg on some blue cheeses Getty Tariffs in the event of a no-deal Brexit Milk There will be no tariffs in place on milk Getty Tariffs in the event of a no-deal Brexit Car Parts There will be no tariffs on car parts imported from Europe PA Tariffs in the event of a no-deal Brexit Cars However finished cars will face tariffs of 10.6% Getty Tariffs in the event of a no-deal Brexit Alcoholic drinks There will be no tariffs on alcoholic drinks - except on some rums due to ingredients used in their distilling process Getty Tariffs in the event of a no-deal Brexit Beef There will be tariffs on beef in order to protect British farmers Getty Tariffs in the event of a no-deal Brexit Fish There will be no tariffs on many types of fish including cod, haddock, salmon and sea bass Getty Tariffs in the event of a no-deal Brexit Fruit and vegetables There will be no tariffs on almost all fruit and vegetables Getty Tariffs in the event of a no-deal Brexit Chocolate There will be no tariffs on chocolate or other cocoa products Getty Tariffs in the event of a no-deal Brexit Poultry There will be tariffs on poultry in order to protect British farmers Getty Tariffs in the event of a no-deal Brexit Ceramics There will be some tariffs in place on ceramis Getty Tariffs in the event of a no-deal Brexit Steel There will be no tariffs on steel Getty Tariffs in the event of a no-deal Brexit Coal There will be no tariffs on coal Getty Tariffs in the event of a no-deal Brexit Lamb/Mutton There will be tariffs on the meat of sheep in order to protect British farmers Getty

It came after another difficult day for Ms May, with EU Council president Donald Tusk telling her the bloc would only approve an extension to Article 50 if she could seal a deal in parliament.

Mr Tusk later told reporters that “hope for a final success may seem frail, even illusory”, but that he would not “give up seeking until the very last moment a positive solution”.

After the PM blamed them for doing “everything possible to avoid making a choice” on either leaving the EU with a deal, without one or not at all, MPs from all sides piled in.

Mr Streeting tweeted: “@theresa_may knows that MPs across the House are subjected to death threats – some very credible. Her speech was incendiary and irresponsible. If any harm comes to any of us, she will have to accept her share of responsibility.”

His Labour colleague Lisa Nandy accused Ms May of “pitting parliament against the people”, saying that to do so was “dangerous and reckless”. She added: “Yesterday her government attacked their civil servants. Now she’s attacking the MPs whose votes she needs. It will have cost her support.”

Sam Gyimah, the Conservative former minister, said that engaging in a “blame game” was “a low blow”.

“Democracy loses when a PM who has set herself against the HoC then blames MPs for doing their job. Distracts from Art 50 extension, all part of her strategy to run down the clock and rule out other options. Toxic,” he added.

Fellow Tory Connor Burns asked of the address: “What was actually the point of that?”

Support free-thinking journalism and attend Independent events

Meanwhile the Liberal Democrats’ Jo Swinson tweeted: “PM says MPs haven’t said what they want??? @LibDems and many others have been crystal clear WE WANT A PEOPLE’S VOTE AND WE WANT IT NOW!”