Sun damage to skin is primarily caused by ultraviolet rays within two ranges: UVA (320-400 nm) and UVB (280-320 nm). UVB causes erythema and direct DNA damage while UVA causes photoaging and generates excessive reactive oxygen species, which cause indirect DNA damage. In addition, UVA can cause immunosuppression that may lead to carcinogenesis. Active ingredients in sunscreens can be divided into two categories: organic and inorganic filters. Inorganic filters, or mineral filters, such as zinc oxide, are usually more chemically inert and do not penetrate as far into the skin compared to organic ones, which makes them ideal for sensitive and baby skin. Zinc oxide is well known for protecting against a wide spectrum of UV. However, mineral combinations, including TiO 2 , are widely used because it is easier to achieve a higher SPF (TiO 2 primarily absorbs in the UVB range). These formulations tend to have a lower UVA absorption, due to low levels of zinc oxide, and tend to leave a white tone and require thick application. Presented here is a new sunscreen formulation which makes use of only zinc oxide to provide a high level of protection against both UVB and UVA radiation, while being suitable for both baby and sensitive skin. This sunscreen composition poses a water-in-silicone (W/Si) emulsion capable of stabilizing a high load of active zinc oxide (22.6%). Both in vitro and in vivo testing demonstrated that the zinc oxide–containing sunscreen had significantly higher PFA than other leading all mineral filter sunscreens. Further In vivo clinical testing showed that these novel zinc oxide sunscreens produced no statistically significant changes for erythema/redness, burning/stinging, and itching, and produced statistically significant improvements in dryness/flakiness and tightness/dry feeling immediately postapplication as well as 1 and 2 weeks later compared with baseline scores in a sample population with atopic dermatitis. Another similar study found similar results with formulation made for children aged 6-36 months. The formulation was also shown to only produce mild and transient ocular stinging, at levels that did not differ from sterile water. Together these data show that this new formulation is a non-irritating sunscreen with a high level of broad spectrum protection without the aesthetic tradeoffs that traditionally have caused people to shy away from inorganic sunscreens.