After installing all updates today, March 8, 2016, MS Access 2010 is no longer able to load all its references when opening a ACCDE or ACCDR file, hence it fails to open. Opening ACCDB works fine. Having removed updates one by one, I have found that it is KB3085515 that causes the problem. The only difference in reference versions that I can see is for the VBE7.DLL. It has updated from 7.0.16.37 to 7.0.16.38.

This error will render anyone that relies on MS Access runtime 2010 with no database since can't not have the VBA reference selected.

How can I get this message to the right people in MS so that they stop this update before it renders several hundred of my UK customers without a system tomorrow?