President Trump Donald John TrumpOmar fires back at Trump over rally remarks: 'This is my country' Pelosi: Trump hurrying to fill SCOTUS seat so he can repeal ObamaCare Trump mocks Biden appearance, mask use ahead of first debate MORE slammed Senate Minority Leader Charles Schumer Chuck SchumerSenate Democrats introduce legislation to probe politicization of pandemic response Schumer interrupted during live briefing by heckler: 'Stop lying to the people' Jacobin editor: Primarying Schumer would force him to fight Trump's SCOTUS nominee MORE (D-N.Y.) on Thursday for saying he should not have pulled out of the Iran nuclear deal, tweeting that, in reality, Schumer does not believe the U.S. should have stayed in the deal.

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Trump also targeted Schumer's defense of former FBI Director James Comey James Brien ComeyDemocrats fear Russia interference could spoil bid to retake Senate Book: FBI sex crimes investigator helped trigger October 2016 public probe of Clinton emails Trump jabs at FBI director over testimony on Russia, antifa MORE after the president fired him last year, saying Schumer thought Comey was terrible before he was fired.

Schumer quickly hit back at Trump on Twitter, citing first lady Melania Trump Melania TrumpMelania Trump: Ginsburg's 'spirit will live on in all she has inspired' The Hill's 12:30 Report - Presented by Facebook - You might want to download TikTok now Warning label added to Trump tweet over potential mail-in voting disinformation MORE's new anti-bullying initiative "Be Best."

The president had ripped Schumer's Iran position during a Cabinet meeting on Wednesday, saying that "they were totally" against the deal from the beginning.

"They don’t say it with their full throat; they don’t say it with heart,” Trump said during a Cabinet meeting. “Because they have one problem: They were totally against it. Like Chuck Schumer was totally against the deal. He voted against the deal.”

“It’s like, oh, perhaps he changed his mind. But, by the way, the deal only got worse," the president continued.

Trump announced Tuesday he would pull the U.S. from the multination deal, which gave Iran billions of dollars in sanctions relief in exchange for accepting limits on its nuclear program.

The president's move marked the fulfillment of one of his major campaign promises.

Schumer originally opposed the deal in 2015 after the Obama administration helped broker it.

"I have decided I must oppose the agreement and will vote yes on a motion of disapproval," Schumer said in 2015.

“To me, the very real risk that Iran will not moderate and will, instead, use the agreement to pursue its nefarious goals is too great.”