Emirates, the Middle East’s biggest airline, said Wednesday that it is cutting flights to the United States because of a drop in demand caused by heightened U.S. security measures and Trump administration attempts to ban travelers from several Muslim-majority nations.

The decision by the Dubai government-owned airline is the strongest sign yet that tougher measures imposed on U.S.-bound travelers from the Middle East are taking a financial toll on fast-growing Persian Gulf carriers that have expanded rapidly in the United States in recent years.