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The Giants are going to need to stop DeMarco Murray and the Cowboys running game if they’re going to leave Dallas with a victory on Sunday afternoon.

Two of the guys that they were counting on to help in that effort have already left the game with injuries. Defensive tackle Cullen Jenkins is doubtful to return after straining his calf in the first quarter and linebacker Jon Beason headed to the locker room as the second quarter got underway.

Beason is recently back from aggravating a toe injury that he suffered in the preseason and it did look like the medical staff was looking at his foot and/or toe before he went to the back.

Murray has 28 yards on six carries and the Cowboys hold a 7-0 lead after Tony Romo found tight end Gavin Escobar in the end zone to open up the scoring.

UPDATE 6:21 p.m. ET: Both players have been ruled out for the remainder of Sunday’s proceedings.