Brisbane's $3 billion facelift begins today.

William Street will close for six years from Sunday, January 1, as work begins to completely transform inner-city Brisbane between George and William streets and let the city's new $3 billion casino and resort complex get under way.

Destination Brisbane concept images for the Queens Wharf mega development in Brisbane.

Star Entertainment and its venture partners make up the Destination Brisbane Consortium, which won the right in 2015 to build the multibillion entertainment precinct near 1 William Street.

The Executive Building and the State Public Works building in George Street, plus the Neville Bonner building in William Street, will all be demolished in 2017.