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SAN DIEGO – A major roundup of 45 alleged gang members and associates around San Diego County Thursday will have a “significant” impact on public safety, although a man considered a lead suspect remained at-large, authorities said.

A drug investigation that started in El Cajon about this time last year snowballed into the arrests of 45 people at numerous locations throughout the region, and that law enforcement officers were still searching for nine other suspects, U.S. Attorney Laura Duffy said at a news conference.

The defendants took part in three conspiracies that overlapped, leading to racketeering charges under the RICO Act, Duffy said.

One suspect who remains at-large, Randy Alton Graves, is considered the lead defendant in the case.

The 50-year-old El Cajon man drives a baby blue Mercedes with paper plates, according to the U.S. Attorney’s Office.

“Today’s RICO charges can be viewed as nothing less than a virtual wrecking ball crashing into the ruthless, ultra-violent West Coast Crips, a gang that has been a scourge on San Diego communities for far too long,” Duffy said.

She said the case will have a “significant” impact on public safety in areas dominated by the gang, such as El Cajon, Spring Valley and the San Diego neighborhoods of Logan Heights and East San Diego.

Authorities said the El Cajon Police Department started a drug investigation last spring and detectives found links to various other cases throughout the region. Eventually, the Bureau of Alcohol, Tobacco and Firearms, FBI and San Diego Police Department got involved.

Duffy said investigators intercepted tens of thousands of “disturbing” phone calls involving the suspects.

“The West Coast Crips gang members think nothing of killing their rivals around San Diego,” Duffy said. “They also think nothing of executing their own.”

One murder case linked to the defendants was of a member of the gang, Paris Hill, who talked to police about a homicide, she said. The 20-year-old man was found mortally wounded in the Webster neighborhood early last month.

Anyone with information on Graves is asked to call the FBI at 858-320-1800.