Giant Pokémon , while rarely playing a large part in terms of plot, are nonetheless a recurring theme in the Pokémon anime . There are several episodes that have a plot revolving around unusually large Pokémon , such to the point that it seems to be a rather common mutation for Pokémon to go through. All Totem Pokémon shown in the anime are giant Pokémon.

Several ancient giant Pokémon appeared in the The Ancient Puzzle of Pokémopolis . These Pokémon were all covered in tattoo-like marks. Gengar emerged from a black vajra-like artifact, Alakazam emerged from a spoon-like artifact, and Jigglypuff emerged from an ancient bell.

In Ruby, Sapphire, Omega Ruby, and Alpha Sapphire, there are two men living in Sootopolis City who respectively want the player to bring them large specimens of Barboach and Shroomish. Likewise, in Pokémon Emerald, the same two men want the player to bring them large specimens of Lotad and Seedot.

In Sun, Moon, Ultra Sun, and Ultra Moon, Totem Pokémon are a type of Pokémon variant that appear at the end of Alola's island trials. Due to the influence of the energy emanated from Ultra Wormholes, these Pokémon appear larger and weigh approximately two to four times as much as other Pokémon of the same species. In Ultra Sun and Ultra Moon the player can obtain Pokémon the size of Totems by collecting Totem Stickers and presenting them to Samson Oak at Heahea Beach.

In Sword and Shield, a phenomenon known as Dynamax can make a Pokémon temporarily grow to giant size, upgrading its moves into Max Moves in the process.

In the side series

In Pokémon GO, Raid Bosses are giant Pokémon with stats that are higher than that of regular Pokémon. Once defeated, they will shrink down to normal size and can be captured.

In Hey You, Pikachu! one of the activities involves Pikachu fishing, and it is possible to fish Pokémon much larger than average. There is also an Oddish that, instead of evolving, grows larger when it is watered, until it is at least ten times Pikachu's size.

In Pokémon Ranger: Guardian Signs, Hocus attacks the player with a giant Crobat when he is faced in the Sky Fortress.

In the Super Smash Bros. series, the player can be temporarily enlarged by eating the Super Mushroom. Jigglypuff's Final Smash, Puff Up can make Jigglypuff gigantic temporarily, plus knocking out any opponent near it.