The first of three UFC events this week takes place on Thursday when UFC Fight Night 80 goes down at The Chelsea at The Cosmopolitan of Las Vegas.

A historic headliner is set to take center stage. For the first time in UFC history, a non-title women’s bout serves as the main event when Rose Namajunas (3-2 MMA, 1-1 UFC) faces Paige VanZant (6-1 MMA, 3-0 UFC).

Both women are jockeying for top-contender status in the strawweight division, and a victory at the UFC Fight Pass-streamed event would be a significant accomplishment.

For more on the numbers behind Namajunas vs. VanZant, as well as the other 22 fighters scheduled to compete, check out 40 pre-fight facts about UFC Fight Night 80.

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Main event

Namajunas competes in her second UFC main event, the second most of any female fighter behind Ronda Rousey (seven).

Namajunas competes in her second UFC bout in a 68-day stretch. She earned a submission victory over Angela Hill at UFC 192 in October.

Namajunas has earned all three of her career victories by submission.

Namajunas is one of 11 fighters in UFC history to earn a standing rear-naked-choke submission win. She accomplished the feat against Hill.

VanZant makes her fourth UFC strawweight appearance, the second most in divisional history behind champion Joanna Jedrzejczyk (five).

VanZant’s three-fight UFC winning streak in strawweight competition is tied for the second longest active streak in the division behind Jedrzejczyk (five).

VanZant’s two stoppage victories in UFC strawweight competition are tied with Jedrzejczyk for the most in divisional history.

VanZant earned the first stoppage victory in UFC strawweight history with her knockout of Kailin Curran at UFC Fight Night 57.

VanZant’s 199 total strikes landed against Felice Herrig at UFC on FOX 15 are the third most ever in a UFC strawweight bout.

Co-main event

Jim Miller (25-6 MMA, 14-5 UFC) competes in his 21st UFC lightweight bout, the second most appearances in divisional history behind Gleison Tibau (26).

Miller’s 14 UFC lightweight victories are third most in divisional history behind Tibau (17) and Donald Cerrone (15).

Miller’s eight stoppage victories in UFC lightweight competition are tied for fourth most in divisional history behind Joe Lauzon (11), B.J. Penn (nine) and Cerrone (nine).

Miller’s six submission victories in UFC lightweight competition are tied for third most in divisional history behind Lauzon (seven) and Nate Diaz (seven).

Miller’s 34 submission attempts in UFC competition are the most in company history.

Michael Chiesa (12-2 MMA, 5-2 UFC) has earned six of his past eight victories by rear-naked choke.

Chiesa is one of 17 fighters in UFC history to earn three or more rear-naked-choke victories.

Remaining main card

Sage Northcutt (6-0 MMA, 1-0 UFC), 19, is the youngest active fighter on the UFC roster and youngest of the 24 fighters scheduled to compete at the event.

Northcutt competes in his second UFC bout in a 68-day stretch. He earned a TKO victory over Francisco Trevino at UFC 192 in October.

Northcutt became the youngest fighter in UFC history to earn a victory when he defeated Trevino.

Northcutt has earned all six of his career victories by stoppage.

Elias Theodorou (11-0 MMA, 3-0 UFC) has earned both of his UFC stoppage victories by knockout.

Thiago “Marreta” Santos (11-3 MMA, 3-2 UFC) has earned all three of his UFC victories by first-round knockout in a total fight time of three minutes and 18 seconds.

Santos’ 29-second knockout of Steve Bosse at UFC Fight Night 70 stemming from a head kick marked the third-fastest finish of its kind behind Nikita Krylov’s UFC on FOX 10 win (25 seconds) and Gegard Gordeau’s UFC 1 victory (26 seconds).

Santos is one of four middleweight fighters in UFC history to earn two sub-minute knockouts.

Santos is one of 15 fighters in modern UFC history both earn and suffer a sub-minute finish.

Preliminary card

Tim Means’ (24-7-1 MMA, 6-4 UFC) is 4-2 since he returned to the UFC for a second stint in May 2014.

John Howard (23-11 MMA, 7-6 UFC) is 3-3 since he returned to the UFC for a second stint in August 2013.

Howard has earned four of his seven UFC victories by split decision. Overall, he’s earned five of his seven wins with the promotion by going the distance.

Howard’s four UFC split-decision victories are tied with Rashad Evans and Benson Henderson for second most in company history behind Tibau (five).

Howard’s knockout of Dennis Hallman at the 4:55 mark of Round 3 at the TUF 10 Finale is the third latest knockout in a three-round UFC fight.

Sergio Moraes (9-2 MMA, 3-1 UFC) competes in just his fifth pro bout since June 2010.

Moraes is one of six fighters in UFC history to earn a mounted-triangle-choke submission win. He accomplished the feat against Neil Magny at UFC 163.

Antonio Carlos Junior (5-1 MMA, 2-1 UFC) makes his second UFC middleweight appearance. He was successful in his divisional debut at UFC Fight Night 70 in July.

Carlos Junior has earned four of his five career victories by submission.

Carlos Junior has landed 10 takedowns in three UFC appearances.

Kevin Casey (9-3 MMA, 1-0 UFC) enters the event on a career-high five-fight undefeated streak He hasn’t suffered a defeat since April 2013.

Johnny Eduardo (27-9 MMA, 2-1 UFC) competes for the first time since May 10, 2014. The bout will mark just his second UFC appearance since May 2012.

Eduardo is 13-1 in his past 14 career bouts.

Santiago Ponzinibbio (20-3 MMA, 2-2 UFC) has earned 17 of his 20 career victories by stoppage. He’s earned 13 of those finishes in the first round.

Andreas Stahl (9-1 MMA, 0-1 UFC) returns to competition for the first time since July 26, 2014. The 502-day layoff is the longest of his career. He made his debut in December 2009.

Nathan Coy (14-5 MMA, 0-0 UFC), 37, is the oldest of the 24 fighter scheduled to compete at the event.

Zubaira Tukhugov (17-3 MMA, 2-0 UFC) enters the event on a career-high eight-fight winning streak. He hasn’t suffered a defeat since May 2012.

For more on UFC Fight Night 80, check out the UFC Rumors section of the site.

FightMetric research analyst and live statistics producer Michael Carroll contributed to this story. Follow him on Twitter @MJCflipdascript.