On the heels of “Runner Runner,” a thriller about a college student who gets caught up in the dangerous world of offshore online gambling, bombing at this weekend’s boxoffice, gamblers in Las Vegas who bet Justin Timberlake wasn’t a movie star, collected millions in winnings.

According to James Reynolds, an oddsmaker who works at Caesar’s Palace, he was so confident that Timberlake had the makings of a movie star, that he convinced Caesar’s to give favorable odds to anyone betting otherwise prior to the opening of “Runner Runner.”

“As a professional handicapper, you have to consider numerous factors when determining the odds of someone becoming a movie star,” Reynolds told Hollywood & Swine. “These factors include Justin’s performance in ‘Social Network,’ the millions of fans of his music career, and his hilarious appearances on ‘Saturday Night Live.’ Unfortunately, I learned the same tough lesson Twentieth Century Fox did this weekend, that none of that matters when it comes to getting people to go to theaters to see him in a movie.”

When reviews of “Runner Runner” came out late last week, where the film and Timberlake’s performance were ravaged by critics, receiving a rating of 8% on Rotten Tomatoes, Caesar’s Palace was forced to stop taking bets on Timberlake’s acting career after the odds of Timberlake becoming a movie star skyrocketed from 2-1 to 500-1, which was eerily similar to what happened last month to the odds of Liam Hemsworth becoming a movie star after reviews of “Paranoia,” were released.

Gamblers who won big this weekend betting against Timberlake’s movie stardom credit doing intensive research prior to betting, which included watching some of Timberlake’s less impressive film performances in the films “The Open Road,” “Southland Tales,” “Edison Force,” “The Love Guru,” and his voiceover work as Boo Boo in “Yogi Bear.”