Mrs. Clinton lost Iowa in 2008 to Mr. Obama but won the caucuses narrowly over Mr. Sanders in 2016. “I’ll be happy to see the primaries start rolling around because that’s a much easier way for people to participate and for the outcomes to be much clearer,” she said.

Some of her most notable remarks in the podcast interview were about the aftermath of the 2016 primary. At one point, Ms. Tisch Sussman asked Mrs. Clinton of Mr. Sanders, “What do you think that he can do — whether he’s the nominee or not the nominee — to help get to that point of unifying people against Trump?”

“Well, he can do it, for one,” Mrs. Clinton said with a big laugh. “That’s not our experience from 2016.”

She said that she had “very honest, very open” conversations with Mr. Obama in 2008 and that she fully embraced his bid for the White House.

“So fast forward. I mean, you had, unfortunately, a very different outcome in the 2016 primary, where I won by four million votes. I won overwhelmingly in delegates,” Mrs. Clinton said. “There was no question about who was going to be the nominee. But unfortunately, you know, his campaign and his principal supporters were just very difficult and really, constantly not just attacking me, but my supporters.”

“We get to the convention,” she continued. “They’re booing Michelle Obama, John Lewis. It was very distressing and such a contrast between what we did to unite in ’08.”