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Police have released CCTV images of two men wanted over a deadly shooting at a Kansas City bar.

Four people died after the two males opened fire inside the bar in the early hours of Sunday (local time).

Police spokesman Thomas Tomasic said the two gunmen apparently got into a dispute with some people inside the bar, left, then returned with handguns.

Around 40 people were inside the small venue at the time.

The gunfire sent patrons running for the exits, with the injured leaving trails of blood as they fled.

“When people came out, they were definitely running,” Mr Tomasic said.

All four men who were killed were Hispanic, but police said authorities do not believe the shooting was racially motivated.

Among the dead was one man in his late 50s, another in his mid-30s and two in their mid-20s, police said.

Shay Celedon, a bar patron who left two hours before the shooting, said one of the men who died had planned to get married next year.

“None of it really seems real right now. We were sitting here yesterday evening having drinks with my best friend’s fiance,” Celedon told CNN.

“I go home, go to bed, get woken up two hours later that he’s deceased, and she held him till he took his last breath, and tried to bring him back and keep pressure on his gunshot wound. And it was just one fatal shot that took him from us.”

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Juan Ramirez of Kansas City told The Kansas City Star his 29-year-old nephew was among those killed.

He said his nephew left behind a six-year-old son and a four-year-old daughter.

“I don’t wish this upon anybody,” Mr Ramirez said.

Officials started getting calls about a mass shooting at the Tequila KC Bar early Sunday morning local time.

“9 shot, 4 dead at 10th and Central Ave,” Kansas City police tweeted.

Agents from @ATFKansasCity are responding to the shooting scene at 10th and Central in Kansas City, KS. @KCKPDHQ for information and updates. pic.twitter.com/u9hnYvD25R — ATF Kansas City (@ATFKansasCity) October 6, 2019

The five others shot were transported to area hospitals and believed to be in stable condition.

“Detectives are here and are looking at any surveillance,” Mr Tomasic said.

“This is definitely one of those that we’re going to do everything very slowly, very methodically and correctly.

Agents from Kansas City’s Bureau of Alcohol, Tobacco, Firearms and Explosives were also at the scene, the agency confirmed on Twitter.