Get Up reacts to the news of Ohio State DE Chase Young being held out against Maryland, saying this is a huge loss for the Buckeyes. (1:50)

Ohio State Buckeyes defensive end Chase Young, a Heisman Trophy contender who has been the most dominant defensive player in the FBS this season, is being held out because of a potential undisclosed violation of NCAA rules, the university announced Friday.

Young, a junior from Hyattsville, Maryland, will not play for the No. 1 Buckeyes in Saturday's game against Maryland "due to a possible NCAA issue from 2018 that the Department of Athletics is looking into," the school said in a release.

Young tweeted Friday that he had accepted a loan from a family friend and is in the process of working with Ohio State and the NCAA to be able to play again.

It is unclear if Young will miss additional games beyond the Maryland contest. Sources familiar with NCAA compliance told ESPN that similar violations can result in multigame suspensions, but that a number of variables -- including who the loan came from, how much it was for, proof of repayment and when the school knew of the violation -- could play a factor.

The Buckeyes have four games remaining in the regular season.

play 1:50 Kiper: Possible NCAA issue won't affect Young's draft stock Mel Kiper Jr. doesn't expect Chase Young's NFL draft stock will be affected in any way by a possible NCAA issue in 2018.

College Football Playoff executive director Bill Hancock told ESPN's Heather Dinich that it would be premature to talk about how Young's absence might impact Ohio State in Tuesday's selection committee ranking.

Tim Nevius, an attorney and former NCAA investigator, confirmed he is working with Young. Nevius tweeted that Young "took a small loan from a close family friend last year to cover basic life expenses. Loan was repaid months ago and we're working to restore his eligibility."

Young leads the FBS with 13.5 sacks and is tied for second with 15.5 tackles for loss.

He tied Ohio State's single-game records for sacks (four) and tackles for loss (five) in the Buckeyes' last game, a 38-7 win over Wisconsin on Oct. 26. He needs a half-sack to tie Vernon Gholston's single-season team record set in 2007.

"Having a player like Chase play the way he has clearly changes the game and makes everybody on that defense better because you have to account for him on every play," Buckeyes coach Ryan Day said after the Wisconsin win. "But that's only good if he plays that way, and he is."

Young, at 6-foot-5 and 265 pounds, is considered a potential No. 1 pick in next spring's NFL draft if he decides to forgo his final season of eligibility with the Buckeyes. ESPN's Mel Kiper Jr. ranked Young as the No. 1 player available for the 2020 draft on his latest Big Board.

Information from The Associated Press was included in this report.