Plus find out where the 'SHIELD' cast stands in the Team Cap vs. Team Iron Man debate.

Could Agents of SHIELD undergo yet another creative overhaul thanks to a Marvel movie?

After Captain America: The Winter Soldier delivered the game-changing twist that Hydra had infiltrated SHIELD from the inside, completely destroying the government organization that makes up the very core of Agents of SHIELD, the ABC Marvel drama became a completely new show in season one. Agent Coulson (Clark Gregg) became Director Coulson of the real SHIELD, working in the shadows to take down the Hydra agents who betrayed them, including their former friend Grant Ward (Brett Dalton). The show was never the same after that revelation, and it was clear from both the critical and fan response that the series was the better for it.

With Captain America: Civil War only weeks away from its box-office bow, Agents of SHIELD is set to change yet again as a result of whatever happens in the Marvel Cinematic Universe.

"It will definitely have a ripple effect," executive producer Jed Whedon says. "It is one world, so if there is a giant event, it will definitely have a ripple effect on our world."

With the Avengers all forced to take sides in the upcoming war between Captain America (Chris Evans) and Iron Man (Robert Downey Jr.), where does the SHIELD team's loyalty rest?

"Lincoln wants to be a part of SHIELD, so as long as Coulson is the director of SHIELD, I'm sure that he's on Team Cap," Luke Mitchell says of the character he plays. "Therefore, Lincoln would be on Team Cap."

"I'm with you on that one [for Mack]," Henry Simmons adds of his character.

But would Coulson actually automatically pick Team Cap?

"It’s a good question. I don’t know yet. I haven’t seen the film," Gregg says. "I think the Coulson from some of the earlier films, especially, would have just been, 'Wherever Steve Rogers goes, I’m going to be there with my cards, and at some point, I’m going to get them signed.' But what’s amazing about doing this character for 70 episodes of television, and putting him at the lead of a no-longer-existing SHIELD that’s hunted around the world, is that you get a very different perspective. I think it’s really going to depend, at such time as Coulson actually has to deal with what’s going on in the Marvel Cinematic Universe, on what has happened here, between now and then, because here is where his focus is right now."

Elizabeth Henstridge and Iain de Caestecker tried talking through both sides of the conflict for their characters, Simmons and Fitz, but they couldn't pick one.

"Hypothetically, you'd expect Fitz to be on the side of technology," Caestecker says.

"Simmons would be Iron Man, right?" Henstridge asks. "I think he could be Cap, right?"

"We're so scared doing interviews," Caestecker adds with a laugh.

As for SHIELD's least enthusiastic team player, Nick Blood thinks that Lance Hunter wouldn't pick sides at all.

"I'm Team Hunter," Blood says. "I don't know whether Hunter would involve himself in those sort of politics."

But Ming-Na Wen, who plays Melinda May, wins for the best answer, hands down.

"Whoever is closer to Thor," Wen says with a laugh.

Agents of SHIELD airs Tuesdays at 9 p.m. on ABC.