The Inner West Council is gearing up for a fight over a mammoth $1.3 billion apartment project, which could see a string of 20 buildings, including towers more than 100 metres tall and comprising 2600 units, built along a key road corridor.

Under a proposal by property giant Mirvac, a large section of Carrington Road in Marrickville would be rezoned for high-rise apartment towers up to 28 storeys, and would see existing business premises demolished to make way for the redevelopment.

An artist impression of Mirvac's proposed $1.3 billion development along Carrington Road, Marrickville.

Labor mayor Darcy Byrne slammed the proposal as "monstrous in scale" and on Thursday night the council voted to oppose the Mirvac proposal in its current form.

"The proponent seems to have confused south Marrickville with downtown Hong Kong," Cr Byrne said.