Beloved entertainer, disability activist, and politician Quentin Kenihan has died suddenly at the age of 43.

Nicknamed the 'little Aussie Battler' for his short stature linked to his medical condition, he died in his hometown of Adelaide on Saturday evening.

Kenihan was best known for his role as Corpus Colossus in Mad Max: Fury Road and had a show about his life on Channel 10.

Beloved entertainer, disability activist, and politician Quentin Kenihan has died suddenly at the age of 43

Kenihan was best known for his role as Corpus Colossus in Mad Max: Fury Road

He first rose to prominence as a child in a series of interviews with Mike Willesee about his brittle bone disease osteogenesis imperfecta.

Due to the congenital disorder, he has suffered more than 570 broken bones in his life. However, his death was reportedly from a suspected asthma attack.

The comedian recently performed at the Adelaide Fringe Festival and published his autobiography Not All Superheroes Wear Capes.

Friends and family were said to be shocked by his sudden death, along with the Australian entertainment community.

He suffered from brittle bone disease osteogenesis imperfecta, causing his small stature and confining him to a wheelchair

Russell Crowe was among the first to pay tribute to him, writing: 'My little mate, the bravest bloke I ever met... gone'

'Devastating news. My little mate, the bravest bloke I ever met... gone. We will meet again... Not confined any more,' Russell Crowe wrote.

'Between your interviews, your book, your one man show, your zany little movies... what a creative and productive life.'

Kenihan's last Twitter post was just the day before his death as part of his campaign for Adelaide City Council, for which he nominated in July.

He earlier this year detailed how Crowe inspired him to keep battling for his life and got him the role in Mad Max.

Kenihan, pictured with an action figure of his Mad Max character, reportedly died from a suspected asthma attack

The Gladiator actor stepped in when Kenihan, who came 'close to death 15 or 20 times' told the world he didn't want to fight anymore in a heartbreaking tweet in 2010.

'He told me to get off my a**e and stop whining about dying and when you've got the Gladiator calling, you listen,' Kenihan told Woman's Day.

Crowe also bought him a life-saving $55,000 portable oxygen concentrator after he started a fundraiser to find the cash.