University of Notre Dame vice-chancellor Celia Hammond is set to replace Julie Bishop as the Liberal candidate for the seat of Curtin.

Ms Hammond wrote to university staff on Monday afternoon telling them she would resign her position immediately.

Notre Dame University vice-chancellor Celia Hammond is slated as the Liberal's pick to replace Julie Bishop in Curtin. Credit:Peter Rae

"It is with mixed emotions that I write to you to advise you that I am bringing forward my resignation and last day at Notre Dame to close of business today, 25 February 2019," she said in the email.

Ms Hammond, who is the daughter of retired WA Chief District Court Judge Kevin Hammond, said "a unique opportunity has arisen which, if I am privileged enough to obtain, will allow me to continue to undertake a role of service".