Walmart Inc. and Target Corp. are among the large retailers and food companies that have sent a letter to U.S. Trade Ambassador Robert Lighthizer warning that proposed tariffs on $200 billion on Chinese goods would hurt consumers and American businesses.

Walmart’s letter, dated Sept. 6, focuses on what it WMT, +0.52% says will be the repercussions of the tariffs, which would apply to goods like food and beverages, personal care products like shampoo, detergents, motor vehicles and paper goods like napkins.

Walmart is the biggest retailer in the U.S.

The tariffs were initially proposed in July and are scheduled to go into effect on Sept. 24. The 10% tax on Chinese imports will rise to 25% on Jan. 1, according to members of the Trump administration.

China said it would impose tariffs on $60 billion worth of U.S. goods. And China’s Commerce Ministry has vowed retaliation and says the proposed U.S. plan has led to “uncertainty” for negotiations between the two countries.

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“Should the tariffs go into effect, Walmart customers will face cost increases for essential items like car seats, cribs, backpacks, hats, pet products and bicycles,” Walmart’s letter says.

The company also said that tariffs would put a commitment to purchase an additional $250 billion in products that support American jobs in jeopardy.

“For lower-income families, a 25% tax on these items would be a serious burden on household finances,” Walmart wrote. “Walmart and our suppliers will pay the cost of increased duties, which are simply taxes levied on products at the border. As a result, either consumers will pay more, suppliers will receive less, retail margins will be lower, or consumers will buy fewer products or forego purchases altogether.”

Walmart outlined the hurdles in finding alternate suppliers, including safety issues on products for children, and the fact that China is the primary or sole source of imports for many products. There are also requirements that new suppliers have to meet, and costs that could come from the change.

The retailer also says that it serves as an exporter of many goods through channels like Walmart China. Many of these items face tariffs as well. Cherries, for example, face 50% duties and, according to Walmart, have seen sales and margins slip.

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Other U.S. items of concern include beef, pork, nuts and wine, which are subject to Chinese retaliation.

Target’s Chief Merchandising Officer Mark Tritton says that retailer is “deeply troubled by and strongly oppose” tariffs, and expressed “disappointment” that the administration would continue to threaten tariffs that will “penalize American families.”

Target is in the midst of a strategic revamp that includes billions of investments in stores and jobs.

“We want nothing more than to play a role in building a stronger and more prosperous American economy for the people we serve,” Tritton wrote.

The comment page for the latest tariff proposal has more than 6,100 comments from companies, organizations and individuals.

The National Retail Federation has also chimed in, with the organization’s President Matthew Shay saying that “thousands” of businesses consider this a “tax on American families.” The NRF has joined a coalition of more than 100 groups called Americans for Free Trade that will oppose tariffs and partnered with Farmers for Free Trade on a campaign that will host town hall events and perform outreach to Congress and the Trump administration on the issue. Events are planned for Chicago, Nashville, Pennsylvania and Ohio.

“It’s disappointing that, despite the voices of those impacted, the administration continues to advance harmful tariff policies that threaten to weaken the U.S. economy,” the statement said. “We cannot afford further escalation, especially with the holiday shopping season right around the corner.”

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The Retail Industry Leaders Association says it is “disappointed” by the tariff announcement as well.

“While we support the Administration’s goal of holding our trade partners accountable, American families, not China, will be paying a new tax on everything from toilet paper to home goods to furniture and pet supplies,” Hun Quach, vice president of international trade for RILA, said in a statement.

Experts and analysts say companies like Best Buy Co. Inc. BBY, -1.61% , Michael Kors Holdings Ltd. US:KORS , and Coach parent Tapestry Inc. TPR, -1.50% could feel the most pressure from tariffs.

“For U.S. companies, the tariffs will have the largest impact on companies that source a significant portion of their products from China, both intermediate and finished goods,” wrote Moody’s analysts in a note published Monday. “The economic fallout of trade barriers is material, with higher tariffs hurting the global economy by distorting prices and creating inefficiencies.”

Moody’s says retailers that deal with furniture, home goods, electronics, hardware, and appliances have the most direct exposure.

“Target’s CEO Brian Cornell put out a statement Monday reiterating the company’s “concern” about anything that would raise prices for consumers, but reassuring shoppers that the retailer is ready for the holidays.

“We’ll continue to watch this situation closely and hope a resolution can be reached soon,” he said.