Side Effects & Safety When taken by mouth: Pomegranate juice is LIKELY SAFE for most people when taken by mouth. Most people do not experience side effects. Some people can have allergic reactions to pomegranate fruit. Pomegranate extract is POSSIBLY SAFE when taken by mouth or applied to the skin. Some people have experienced sensitivity to pomegranate extract. Symptoms of sensitivity include itching, swelling, runny nose, and difficulty breathing.



The root, stem, or peel of pomegranate is POSSIBLY UNSAFE when taken by mouth in large amounts. The root, stem, and peel contain poisons.



When applied to the skin: Pomegranate extract is POSSIBLY SAFE when applied to the skin. Some people have experienced sensitivity to pomegranate extract. Symptoms of sensitivity include itching, swelling, runny nose, and difficulty breathing. Special Precautions & Warnings: Pregnancy and breast-feeding: Pomegranate juice is POSSIBLY SAFE for pregnant and breast-feeding women. But there is not enough reliable information about the safety of using other forms of pomegranate, such as pomegranate extract. If you use pomegranate during pregnancy or breast-feeding, stick with the juice.



Low blood pressure: Drinking pomegranate juice can slightly lower blood pressure. Drinking pomegranate juice might increase the risk of blood pressure dropping too low in people who already have low blood pressure.



Allergies to plants: People with plant allergies seem to be more likely to have an allergic reaction to pomegranate.



Surgery: Pomegranate might affect blood pressure. This might interfere with blood pressure control during and after surgery. Stop taking pomegranate at least 2 weeks before a scheduled surgery.



