nVidia Quake Champions GPU Profile

In your Nvidia Control Panel -> Manage 3D settings -> Program Settings, QuakeChampions.exe and set:

Pre-rendered frames 1 or 2 (test for personal preference, 1 gives the lowest possible input lag, 2 may be smoother)

Refresh rate - highest available (when changing from desktop resolution, games don't always choose the highest refresh rate. this will make sure it does)

Threaded optimization on or off (test as this is system specific, on usually gives better frame rate, off has been know to cure a severe input lag issue on some systems)

Clean Graphics Drivers

AMD and Nvidia users should consider using Display Driver Uninstaller (DDU) in Windows Safe Mode to wipe your graphics drivers completely removing all traces of past installs, and then install the latest from nvidia.com or amd.com (not opting to accept cookies may cause scrolling the page to fail)

Update Operating System

Check Windows (Start) button -> Settings -> Updates and Security (windows update on older systems) and hit 'check for updates', ensure you have all updates installed.

Consider upgrading to Windows 10 v1709 "Fall Creators Update" especially if currently using Win10 v1703 "Creators Update" as that version has specific stuttering bugs in many games which Microsoft has addressed with this new version (source).

You can force an upgrade, download an ISO or build a USB memory stick to upgrade or install clean via https://www.microsoft.com/en-gb/software-download/windows10.

After install it is recommended to then follow the instructions above in the Clean Drivers section to DDU wipe and then install the latest GPU drivers, as windows updates often install driver versions that cause major problems for games.

There is a user compiled list of known changes in the Fall Creators Update more comprehensive than the Microsoft changelog here

*Yakumo's Disclaimer*

Driver and software updates, Windows updates and the use of uninstall tools are taken entirely at the users own risk, and subject to the disclaimers of the driver, update or uninstall tool authors. Should any problems occur with the process the support of the tool or update's author should be sought.