Clowes is also set to write the script for the adaptation of the Fantagraphics 2016 best-seller, which explores the lengths to which one man will go, and the sacrifices he will make, for the love of his life. When his wife, Patience, is murdered, Jack falls into a deep pit of anger, grief and guilt. Ten years later, he learns of a time machine that might allow him to fix things, launching him into a psychedelic journey through Patience’s past and the events that shaped her into the woman he knew and loved.

Focus will hold worldwide rights to Patience as part of the company’s renewed global initiative. “Daniel’s story is beautifully imagined," said Jim Burke, Focus president of production, in a statement. "As with all of his works, it is vivid and affecting. Patience will be a thrilling, funny, and moving exploration of emotions we’ve all experienced."

Clowes was an Academy Award nominee in the Best Adapted Screenplay category for Ghost World, based on his comic, which he scripted with director Terry Zwigoff. He also wrote the adaptation of his graphic novel Wilson, directed by Craig Johnson and starring Woody Harrelson and Laura Dern. Fox Searchlight will release Wilson in March 2017.