LOS ANGELES, CA - MARCH 06: Actor Seth Green arrives at the premiere of Walt Disney Pictures' "Mars Needs Moms" at the El Capitan Theater on March 6, 2011 in Los Angeles, California.

The stop-motion sketch comedy will debut in the fall and feature characters from the legendary superhero universe.

The Robot Chicken gang is entering the superhero world.

Robot Chicken creators Seth Green and Matthew Senreich are teaming with DC Comics and Warner Bros. Animation for a one-time special taking place within the universe that features the likes of Superman, Batman and Lois Lane.

Set to air in the fall on Cartoon Network's Adult Swim, the voice cast includes Green as Batman, Robin and Aquaman; Paul Reubens as the Riddler; Neil Patrick Harris as Two-Face; Alfred Molina as Lex Luthor; Nathan Fillion as the Green Lantern; Megan Fox as Lois Lane; and Breckin Meyer as Superman. Additional voice cast includes Senreich, Abe Benrubi, Alex Borstein, Clare Grant, Tara Strong, Tom Root and Zeb Wells.

"Working with Seth and Matthew and the rest of the Robot Chicken crew has always been nothing short of insanity over the years," DC Entertainment chief creative officer Geoff Johns said. "DC, Warner Bros. Animation and Adult Swim together -- how could anyone resist?"

The Robot Chicken DC Comics Special becomes the latest effort for the Emmy-winning series to skewer another universe and follows the series' popular Star Wars installments.

"Having been raised on DC Comics and the Super Friends vs. Legion of Doom, it's exciting to tell a whole Robot Chicken story within this awesome universe," Green said.

Added Senreich: "We've been working with Johns for over 15 years, so playing together on this special only made it more fun to work in the worlds we all love so dearly."

Green will direct the 22-minute special, which was penned by co-head writers/co-executive producers Douglas Goldstein and Tom Root along with Robot Chicken writers Green, Senreich, Wells, Mike Fasolo, Matthew Beans and DC Entertainment’s Johns, Franklin & Bash's Meyer and MAD's Kevin Shinick, who also serves as the narrator, and with Ethan Marak, who co-produces. EPs include Green, Senreich, Johns, Sam Register, John Harvatine and Eric Towner.

The special comes shortly after Green and Senreich's Stoopid Monkey and Buddy Systems united in December to form Stoopid Buddy Stoodios.

UTA brokered the deal.

Email: Lesley.Goldberg@thr.com; Twitter: @Snoodit