A health alert has been issued to people who have eaten kebabs at a southern Sydney shop, after four people were hospitalised with a rare bacterial gastroenteritis.

NSW Health said the patients became sick from the Shiga-toxin producing E. coli (STEC) in the Sutherland area on Thursday.

It was revealed that all four had eaten food from Kenny's Kebabs at Westfield Miranda between January 4 and 8.

NSW Food Authority officials went to the shop on Friday and found a number of concerns associated with food handling and preparation.

As a result, a prohibition order was served, stopping the business from trading until further notice.