House Minority Leader Nancy Pelosi (D-Calif.) on Friday praised Sen. John McCain John Sidney McCainMomentum growing among Republicans for Supreme Court vote before Election Day McConnell urges GOP senators to 'keep your powder dry' on Supreme Court vacancy McSally says current Senate should vote on Trump nominee MORE's (R-Ariz.) announcement that he would not support the latest GOP effort to repeal and replace ObamaCare and pledged Democrats will "put a stake in the heart of this monstrous bill."

In a letter to Democrats, Pelosi touted McCain's decision as "good news."

But she also cast Democrats' health-care fight against Republicans as ongoing, urging lawmakers and advocacy groups to keep pressure on GOP lawmakers and the discussion in front of the public.

"Together, we will finally put a stake in the heart of this monstrous bill," Pelosi wrote.

We finally have a chance to put a stake in the heart of the #Trumpcare monstrosity. We can’t let up. The next days are crucial in this fight — Nancy Pelosi (@NancyPelosi) September 22, 2017

The letter came after McCain said that he could not support a measure authored by Sens. Lindsey Graham Lindsey Olin GrahamMcConnell locks down key GOP votes in Supreme Court fight Will Republicans' rank hypocrisy hinder their rush to replace Ginsburg? Momentum growing among Republicans for Supreme Court vote before Election Day MORE (R-S.C.) and Bill Cassidy William (Bill) Morgan CassidyCoushatta tribe begins long road to recovery after Hurricane Laura Senators offer disaster tax relief bill Bottom line MORE (R-La.), which sought to repeal much of the Affordable Care Act by replacing certain provisions, like Medicaid subsidies, with block grants controlled by states.

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While several other Senate Republicans remain undecided, McCain's announcement dealt a potentially deciding blow to the proposal.

Republicans could only afford two defections on the bill to get the 50 votes necessary for it to pass. But Sen. Rand Paul Randal (Rand) Howard PaulSecond GOP senator to quarantine after exposure to coronavirus GOP senator to quarantine after coronavirus exposure The Hill's Morning Report - Sponsored by National Industries for the Blind - Trump seeks to flip 'Rage' narrative; Dems block COVID-19 bill MORE (R-Ky.) has already come out against the measure, and Sen. Susan Collins Susan Margaret CollinsMcConnell locks down key GOP votes in Supreme Court fight Most Americans think winner of election should pick next Supreme Court justice: poll Murkowski: Supreme Court nominee should not be taken up before election MORE (R-Maine) has indicated that she's leaning against supporting it.

McCain's decision could potentially prompt other Senate Republicans to come out in opposition. No Democrats are expected to vote for the measure.

The Graham-Cassidy bill is the GOP's latest push to repeal the Affordable Care Act, or ObamaCare, though they now face a procedural deadline of Sept. 30 to pass the bill with only 50 votes, assuming Vice President Pence would cast the tie-breaking vote.

After that, any health-care bill would require a filibuster-proof 60 votes — a majority that would require Democratic support.