pernicious , baneful , noxious , deleterious , detrimental mean exceedingly harmful. pernicious implies irreparable harm done through evil or insidious corrupting or undermining. the claim that pornography has a pernicious effect on society baneful implies injury through poisoning or destroying. the baneful notion that discipline destroys creativity noxious applies to what is both offensive and injurious to the health of a body or mind. noxious chemical fumes deleterious applies to what has an often unsuspected harmful effect. a diet found to have deleterious effects detrimental implies obvious harmfulness to something specified. the detrimental effects of excessive drinking

insidious , sinister , or pernicious ?

Few would choose to be associated with people or things that are insidious, sinister, or pernicious; all three of these words have decidedly unpleasant meanings, each with its own particular shade of nastiness.

Insidious comes from a Latin word for “ambush” (insidiae), which is fitting, as this word often carries the meanings “deceitful,” “stealthy,” or “harmful in an imperceptible fashion.” The first two meanings may be applied to people or things (“an insidious enemy,” “an insidious plot”), while the last is usually applied to things (“insidious problems,” “insidious sexism”), in particular to the gradual progress of a disease (“an insidious malignancy”).

Sinister comes from a Latin word meaning “on the left side, unlucky, inauspicious.” Although it is commonly used today in the sense “evil” (“a sinister cult leader”; “a sinister plot”), it may also suggest an ominous foreshadowing of some unfavorable turn of events (“a sinister omen”).

Pernicious has largely stayed true to its etymological root, the Latin noun pernicies “ruin, destruction.” Its original meaning in English, “highly injurious or destructive,” usually applies to things (“pernicious apathy,” “pernicious effects”) and medical conditions (“pernicious fever,” “pernicious anemia”). When applied to people, pernicious means “wicked.”