While the gay and lesbian community is celebrating the Supreme Court ruling that struck down California's Defense of Marriage Act, another group can also be happy about high court decisions this term—the U.S. Chamber of Commerce.

According to the Constitutional Accountability Center (CAC), the chamber has a 78 percent success rate in recent Supreme Court decisions, finding itself on the winning side in 14 out of 17 cases in which it filed amicus briefs.

An amicus brief is a court document filed by a party not directly related to a case, but which is used to influence the court's decision.

(Read More: Supreme Court Strikes Down DOMA)

"We've studied this the past few years and the chamber is more successful now than in previous terms," said Judith Schaeffer, vice president of the CAC, a think tank and law firm.

Since 2006, the chamber has won 70 percent of its cases, compared with 56 percent during a comparable period when William Rehnquist was chief justice from 1985 to 2005, said the CAC.

"The court doesn't hold for business in every case, but it's a conservative court and more often than not, they agree with the chamber," Schaeffer said. "And when you have these cases closely divided and along a 5-4 vote, the chamber almost always wins."

The Chamber of Commerce, which represents the interests of more than 3 million American businesses, chose not to comment for this story after being contacted by CNBC.