The Borgia family is at the brink of power as Rodrigo Borgia is elected as Alexander VI, Pope of Rome. The life of this enigmatic family evolves overnight as they are thrust into the highest seat of power in the Christendom. The story of this family's evolution from nothing to notoriety and their transformation into the most sinister family to hold the papal throne is best told through Lucrezia Borgia. Follow her journey from an innocent girl, naive of her families sinister plots throughout Italy, to becoming the women known throughout history for incest, murder, and seduction.