It's the "Snakes on a Plane" sequel -- "Snakes on an 'Extra' Junket"!

As "Extra's" Terri Seymour chatted up "Grown Ups" stars Salma Hayek, Maria Bello and Maya Rudolph, they got an expected guest -- a harmless but rather large snake --- which sent the girls into a tizzy, as they scrambled to get away from the reptile, especially the frantic, screaming Salma.

"It was like a python. It was thick. Its head was like this like a cobra!" Bello exclaimed afterward.

And what about Salma? "She split. She's on the next plane," Rudolph said. "She's in the hospital," Bello laughed.

Check out the hilarious raw reactions!

"Grown Ups" opens in theaters June 25.