A Manhattan husky named Mystery is a serial killer who has taken down five fellow pooches — including an adorable Yorkie whose master is suing over one of the slayings, according to a Friday court filing.

Amisha Mulji has a serious bone to pick with the owner of the unmuzzled 7-year-old beast, which slaughtered her retired emotional support dog, C.J., while they were on a walk in Washington Heights in September, the New York Supreme Court lawsuit states.

The killer canine sunk its teeth into her 7-pound Yorkie and “shook [him] back and forth like a rag doll,” according to the suit against the husky’s owner, Mindy Gordon, who lives on West 176th Street near Broadway.

“I was panicking. He had blood on his lower abdomen,” said Mulji, a 37-year-old who works in marketing. “My dog was crying. He’s a small dog, and after three minutes, he just goes limp.”

She rushed C.J. to animal hospital emergency room, where he died from “enormous blood loss,” according to court papers.

After his heartbreaking death, Mulji says she learned through police reports that the husky had struck before — attacking or butchering at least four other dogs.

In May 2015, Mystery disemboweled a Shih Tzu and later killed an unspecified pup in October 2018, according to the court filing. The animal also roughed up two small dogs, who survived, in October 2015.

But less than a week after C.J.’s death she spotted Gordon walking the four-legged menace again — sans a muzzle — through a park in the neighborhood, she said.

Mulji then sued for negligence, seeking $150,000 to cover vet bills and other damages.

The suit also demands that Gordon seek dog training and adopt “measures to ensure that Mystery does not pose a danger to public safety.”

But Gordon fired back Friday, saying her pooch is “well-behaved,” that the Yorkie was a “yapping menace” and that Mulji was on the phone, not paying attention at the time of the attack.

“My dog’s not a killer,” she said. “He has lots of little dog friends that he plays with.”

She claimed Mulji had made up the story as a scheme to get cash.

“I just think this woman is pure evil,” she said. “It’s all a scam for money,”

Mulji has since launched a pet CPR group and has taken to Facebook to warn others about the dangerous dog.

“Please help me spread the word…before [Mystery] kills more #dogs or hurts more people!” she warned.