SANTA CLARA — Frank Gore can reach a milestone Sunday when the 49ers visit Tampa Bay in his native Florida: He can become the 20th running back in NFL history to eclipse the 1,000-yard mark for a seventh season.

Gore has rushed for 931 yards this season as the 49ers (9-4) close in on their third consecutive playoff berth (and third in Gore’s nine-year career).

“It’s a great chance to play in front of my family,” said Gore, who grew up some four hours away in Coral Gables. His three sons (ages: 11, 9 and 4) live in the Miami area.

An ankle issue has Gore listed as probable for Sunday’s game against the Buccaneers (4-9). He’s played in every game since 2011, so don’t expect him to sit out this one.

“It’s a big game,” Gore said. “They’re a good team. They’re fast, physical and play hard.”

The 49ers’ all-time rushing leader has played only once in Florida since leaving the University of Miami: a 2005 loss at Jacksonville, where he rushed for 79 yards in his rookie season.

Gore needs to average 77 yards over the final three regular-season games to reach the 10,000-yard plateau for his career. He’s run for over 1,000 yards in every season other than his rookie year (608 yards, as a backup) and in 2010 (853 yards, missed final four games with a hip injury).

Tight end Vernon Davis said “may the best man win” when it comes to his downfield matchups with former teammate and current Bucs safety Dashon Goldson. “He’s fast, quick, and when he hits you, it’s a strike, and he can do it hard,” Davis said. “I enjoyed seeing it when he was here.” Davis has a team-high 11 touchdowns this season, and one more would make him the only tight end in NFL history to record two seasons with 12 touchdown receptions. He had 13 in 2009. Davis ranks first among tight ends this season with an average of 16.5 yards per catch.

Left guard Mike Iupati (left knee), wideout Mario Manningham (left knee), cornerback Tarell Brown (right ribs) and tight end Vance McDonald (ankle) are questionable. Coach Jim Harbaugh said it’s “still a possibility” that Iupati could return from a three-game absence.

All players on the roster practiced for a second consecutive day, including Michael Crabtree, who’s listed as probable with an ankle sprain. Also probable are defensive tackles Justin Smith (shoulder) and Ray McDonald (ankle), linebackers Aldon Smith (shoulder) and Dan Skuta (foot), left tackle Joe Staley (knee), guard Adam Snyder (not injury related), wideout Jon Baldwin (shoulder) and safety Craig Dahl (ankle).