LONDON — Kim Jones will leave his role as artistic director of men’s wear at Louis Vuitton after the fall 2018 catwalk show on Thursday, the French luxury house has announced, capping months of speculation that he might be departing and prompting questions about where in the fashion world he might go next.

Mr. Jones, an Englishman who held his position at Louis Vuitton for seven years, is the fifth major designer to leave a job in six weeks, including Phoebe Philo from Céline and Jonathan Saunders from Diane von Furstenberg in December. He is a Central Saint Martins graduate who founded his own men’s wear line in London, closing it in 2008 to become creative director of Dunhill and then moving to Louis Vuitton in 2011.

Mr. Jones has been widely applauded for revitalizing the Vuitton men’s wear line for a younger generation, mixing the house’s travel heritage (at the highest end of the price spectrum) with a more street-friendly style.

“These houses are under tremendous pressure to be right on the money of what certain generations want,” said Michael Hainey, the executive director of editorial for Esquire magazine. “He showed just how you can take something that’s got a fantastic heritage and still do something very modern with it.”