Donald Trump's speaking cadence became irregular and his speech slurred through part of his speech Wednesday announcing changes to America's Israel policy.

Speculation about the oratory oddity became national water-cooler talk after Trump finished his remarks by saying 'God bless the United Shhtates. Thank you very much-sh.' A White House spokesman says the president merely had a case of 'dry mouth.'

Conspiracy theorists on Twitter launched into high gear, including Democratic partisans who speculated about every possible cause from a mini-stroke to cocaine use.

But a Virginia dentist consulted by DailyMail.com watched a video of the speech Wednesday afternoon and concluded that the speech quirk 'sounds like a loose denture plate.'

'Saliva can get trapped between an upper plate and the palate – or between the lower plate and the lower jaw – and that's what makes the noise,' he said.

Poligrip emergency? President Donald Trump slurred his speech at times during a speech on Wednesday, which a dentist tells DailyMail.com could be related to a loose denture plate

Washington, we have a problem: Trump, announcing changes in the U.S. policy toward Israel, ended his speech by saying: 'God bless the United Shhtates'

He also speculated that it's also 'a bit like what you get when you try to talk after you lose a filling.'

But he ultimately said the denture hypothesis is more likely.

The president took in air through his nose during the last third of his remarks, the dentist noted, developing a pointed lisp only when he breathed through his mouth instead.

'You don't want a lot of air rushing through your mouth when you have a loose plate,' he said.

The dentist is board-certified but declined to be identified publicly, saying he's 'not about to wade into politics.'

'The last thing I need is for half my patients to get the wrong idea,' he said.

The real thing? Trump's pearly whites at times look too perfect to be natural

It's unknown whether the president has dentures. The White House initially didn't respond to requests for comment about what caused the slurring.

But Trump did seem to adjust the lower half of his mouth, moving his jaw from side to side at times, in between lines of his speech.

White House spokesman Raj Shah dismissed the speculation in the afternoon, telling the Los Angeles Times that 'his throat was dry. There’s nothing to it.'

Asked if Trump had any related health concerns, Shah said: 'I know what you’re getting at. I’m saying there’s nothing to it.'

In 2015 a Daily Beast columnist wrote that his own dentist showed off a mold of the future president's teeth, saying Trump's habit was to come in for a new set of ever-whiter tooth veneers every six months.

The writer placed the episode 15 years earlier, however. Trump could have acquired dentures or tooth fillings since then.

The dentist who spoke with DailyMail.com on Wednesday said it was 'more likely' that Trump had dentures than fillings.

'He's 71 years old,' he said, 'although the president can certainly afford the best oral hygiene in the world.'

An Obama-era White House ethics expert said the lack of attention given to Trump's speaking quirk, compared with the crush of news stories about Hillary Clinton's health problems las tyear, was proof of 'sexism in politics'

'My mouth used to get dry like this when I was using drugs,' suggested an organizer of a national anti-Trump march

A Salon.com writer tweeted: 'Looks stroke-ish'

Most of the less sober theories on Twitter were from liberals who seemed to hear what they wanted to hear.

Walter Shaub, an Obama-era former director of the Office of Government Ethics, compared Trump's pronunciation slip with last years's national fascination over Democrat Hillary Clinton's bout with influenza.

'It's amazing that the media ignores the spectacle of POTUS slurring words in a speech, given the frenzy over the health of a rival who proved her stamina doing shuttle diplomacy around the world,' Shaub tweeted.

'I don't know how to make sense of it except as evidence of the sexism in politics.'

'He couldn't quite control his mouth. Looks stroke-ish, but could be, I dunno, dental?' speculated Salon.com writer Bob Cesca.

The president appeared Wednesday in front of a portrait of George Washington, who famously had his own set of false teeth – made of wood

Holly O'Reilly, an organizer of the anti-Trump 'March for Truth,' had her own theory.

'Is Trump using again?' she asked in a tweet. 'My mouth used to get dry like this when I was on drugs. Is he having a stroke?'

Trump is famously anti-drug and doesn't consume alcohol. His older brother died in his 40s as a consequence of heavy drinking.

He wouldn't be the first U.S. president to do the job with dentures in place.

George Washington famously had false teeth made of wood. John Adams refused to get dentures in his old age, developing a severe lisp.

Trump was speaking Wednesday to announce that the U.S. is recognizing Jerusalem as Israel's capital, and beginning the process of relocating its embassy there from Tel Aviv.