Protect the QB

Mariota has already been sacked 29 times in nine games this season – and he missed one game, and parts of three others. He was sacked four times in the first half on Sunday before leaving, The Titans face a big challenge against a Texans defense that can get after the QB. Texans defensive end J.J. Watt already has 10 sacks on the season, and in his last 10 games against the Titans he has 14.5 sacks, and seven forced fumbles. The Texans didn't have Jadeveon Clowney in the Week 2 game, and he's back.

Corey Davis and Co.

The Titans will be without receiver Taywan Taylor for the third straight game, but the team has playmakers. And they need them to make plays. Receiver Corey Davis has been spectacular on two Sundays this season, and he's made significant strides in Year 2. The Titans need him to make plays on MNF, but will also count on others, from Tajae Sharpe to Cameron Batson to Darius Jennings. The tight ends need to contribute as well.

Run the Ball

Titans running back Derrick Henry has raised his game since the bye. He's averaged over five yards per carry in the last three games, and he's scored three touchdowns. Running back Dion Lewis has made an impact himself. To slow down Houston's rush, the Titans need to have some success in the running game. Lewis is capable of turning in an all-around performance – he has 120-scrimmage yards in two of the last three games on the road.

Contain Hopkins