ARLINGTON, Texas -- Derek Holland will make his first rehab start Wednesday with the Triple-A Round Rock Express.

Holland, who went on the disabled list after experiencing shoulder fatigue and a stomach ailment after his last start on June 5, will throw around 50 pitches Wednesday before throwing a bullpen on Friday in Arlington. He is expected to make his second rehab start with Round Rock next Monday.

The left-hander will face the Nashville Sounds in his first start with the Express.

Holland is 5-4 with a 5.10 ERA on the year, including six quality starts. He lost 15 pounds in two and a half weeks due to the stomach ailment.

Holland's most recent bullpen session was Sunday, where he threw 40 pitches. It is expected that he will need three rehab starts before rejoining the Rangers.

Matt Harrison reiterated Monday that he expects to make his next start after leaving Sunday's win over the Colorado Rockies with lower back tightness.

Harrison had a shutout going when he experienced some stiffness and was lifted after five innings.

"In the third inning it was stiff on me and it took a couple of batters to get back to normal," Harrison said. "Then after that I came in and asked for a stretch after the fourth. They asked what was wrong and I said, 'Nothing, it's just stiff.' I went back out for the fifth and after that they told me I wasn't going back out."

The left-hander went through his normal workout routine Monday, but he is going to stay away from any weightlifting that would put stress on the back.

Manager Ron Washington is confident Harrison won't miss any time.

"It was him saying he felt some stiffness and us reacting to it," Washington said of taking him out of the game. "It would have been very bad if we had left him out there and if he would have thrown a pitch and something happened."

David Collier is a contributing writer for ESPNDallas.com