While about 5% of women have premenstrual dysphoric disorder, we more commonly see women who experience premenstrual exacerbation of mood and anxiety disorders. A small study of 15 women with borderline personality disorder (who were not taking psychotropic medications or hormonal contraceptives) suggests that most symptoms attributable to borderline personality disorder significantly worsened in the week before and during the first week of menstruation. (This is somewhat delayed from what is typically observed in patient with PMDD who typically experience resolution of symptoms with the onset of menses.)

Ruta Nonacs, MD PhD

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Menstruation may worsen symptoms in borderline personality disorder (Psychiatric Annals)



Eisenlohr-Moul TA, et al.Perimenstrual exacerbation of symptoms in borderline personality disorder: evidence from multilevel models and the Carolina Premenstrual Assessment Scoring System. Psychol Med, May 2019.