AIM OF THE STUDY γ-Mangostin is a xanthone found in the fruit hulls of Garcinia mangostana L., which have long been used in Southeast Asia as a traditional medicine for the treatment of abdominal pain, dysentery, wound infections, fever and convulsions. Recent studies have revealed that γ-mangostin exhibits a variety of pharmacological activities, including serotonin 2 (5-HT(2)) receptor antagonism, anti-inflammatory effects and analgesic effects. To explore the mechanism of γ-mangostin… CONTINUE READING