China's first lady Peng Liyuan looks at Chinese President Xi Jinping (R) as she sits next to Trump Senior Advisor Jared Kushner and Ivanka Trump (L), during a dinner at the start of a summit between U.S. President Donald Trump and Chinese President Xi at Trump's Mar-a-Lago estate in West Palm Beach, Florida, U.S. April 6, 2017. REUTERS/Carlos Barria

SHANGHAI (AP) — The arrest and disappearance of three labor activists investigating a Chinese company that produces Ivanka Trump-branded shoes in China prompted a call for her brand to cease working with the supplier and raised questions about whether the first family's commercial interests would muddy U.S. leadership on human rights.

The men were working with a U.S. nonprofit to publish a report next month alleging low pay, excessive overtime and possible misuse of student labor, according to China Labor Watch executive director Li Qiang, who lost contact with the investigators over the weekend. China Labor Watch has been exposing poor working conditions at suppliers to some of the world's best-known companies for nearly two decades, but Li said his work has never before attracted this level of scrutiny from China's state security apparatus.

The arrest and disappearances come amid a crackdown on perceived threats to the stability of China's ruling Communist Party, particularly from sources with foreign ties such as China Labor Watch. Faced with rising labor unrest and a slowing economy, Beijing has taken a stern approach to activism in southern China's manufacturing belt and to human rights advocates generally, sparking a wave of critical reports about disappearances, public confessions, forced repatriation and torture in custody.

China Labor Watch's investigation also had an unusual target: a brand owned by the daughter of the president of the United States.

"Ivanka's brand should immediately cease its work with this supplier, and the Trump administration should reverse its current course and confront China on its human rights abuses," Adrienne Watson, spokeswoman for the Democratic National Committee, said in a Wednesday email. Ivanka Trump must decide, she added, "whether she can ignore the Chinese government's apparent attempt to silence an investigation into those worker abuses."

Ivanka Trump's lifestyle brand imports most of its merchandise from China, trade data show. She and her father both have extensive trademark portfolios in China, though neither has managed to build up a large retail or real estate presence here. The sister of Jared Kushner, a Trump adviser and husband of Ivanka, travelled to China this past month to court investment from Chinese families for a real estate project in New Jersey.

"The eagerness of members of the family to do business in China while airbrushing very troubling human rights and labor rights records of the country is troubling," said Nicholas Bequelin, East Asia director for Amnesty International. We'll have to wait and see, he added, "to what extent business is trumping any kind of consideration of the diplomatic capital of the U.S. in promoting human rights, labor rights and democracy." Amnesty International called for the release of Hua Haifeng on Wednesday, as well as his two colleagues, who are feared to have been detained.

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White House spokeswoman Hope Hicks referred questions to Ivanka Trump's brand. The Ivanka Trump brand declined to comment.

Abigail Klem, who took over day-to-day management when the first daughter became a White House presidential adviser, has said the brand requires licensees and their manufacturers to "comply with all applicable laws and to maintain acceptable working conditions."

China tightened control over foreign NGOs starting this year by requiring them to register with state security. Chinese Foreign Ministry spokeswoman Hua Chunying said at a regular press briefing Wednesday that she was not aware of the arrest and disappearances. She said China welcomed international NGOs to carry out research, but added, "we also hope that NGOs can also observe Chinese laws and regulations and don't engage in any illegal actions or behavior."

Hua Haifeng was accused of illegal surveillance, according to his wife, Deng Guilian, who said the police called her Tuesday afternoon. Deng said the caller told her she didn't need to know the details, only that she would not be able to see, speak with or receive money from her husband, the family's breadwinner.

Li said China Labor Watch asked police about the Deng and the two other investigators, Li Zhao and Su Heng, on Monday but received no reply. Li added that a friend had tried to file a missing person report on Li Zhao in Jiangxi province, but was told he had to do so in the man's hometown.

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