Heterochromia refers to a difference in coloration, usually of the iris but also of hair or skin. Heterochromia is a result of the relative excess or lack of melanin (a pigment). It may be inherited, due to genetic mosaicism, or due to disease or injury.

Eye color, specifically the color of the irises, is determined primarily by the concentration and distribution of melanin. The affected eye may be hyperpigmented (hyperchromic) or hypopigmented (hypochromic). In humans, usually, an excess of melanin indicates hyperplasia of the iris tissues, whereas a lack of melanin indicates hypoplasia.

Heterochromia of the eye (heterochromia iridis or heterochromia iridum) is of two kinds:

In complete heterochromia, one iris is a different color from the other.

In partial heterochromia or sectoral heterochromia, part of one iris is a different color from its remainder.

Though I personally don`t have heterochromia, I`m very interested in this anomaly, knowing a lot of people with this abnormality.

Actually, many hollywood actors/actresses have it though it`s not always noticeable, due to the partial heterchromia. Here are some celebrities who have both partial & complete heterochromia:

Kate Bosworth – Right eye partial brown/blue, Left eye blue

Jane Seymour – Right eye partial brown/green, Left eye green



Mila Kunis – Left eye hazel, Right eye green

Demi Moore: Right eye hazel, Left eye green

Alice Eve : Right eye green, Left eye blue

Elizabeth Berkley: Right eye partial brown/green, Left eye green

Jessica Cauffiel: Left eye partial brown/green, Right eye green

Idina Menzel: sectoral heterochromia

Henry Cavill : Left eye partial brown/blue, Right eye blue

Jonathan Rhys Meyers : Left eye partial hazel/blue, Right eye blue

Josh Henderson : Left eye green, Right eye blue

Keifer Sutherland : sectoral heterochromia (both eyes partial green/blue)

Benedict Cumberbatch: sectoral heterochromia

Marshall Lancaster : sectoral heterochromia (right eye hazel/blue, left eye blue)



Simon Pegg : sectoral heterochromia (both eyes partial brown/blue)

Christopher Walken : partial heterochromia (both blue with green inner rings)

Dan Aykroyd: complete heterochromia (right eye green, left eye brown)

Joe Pesci: partial heterochromia (both eyes partial blue/brown)