Oh honey, does Will & Grace have some fun in store for season 2.

EW has learned exclusively that Chelsea Handler has been cast as Donna Zimmer, a high-powered client of Grace’s (Debra Messing) who starts dating her bitter sister Janet (Mary McCormack, who is returning to the comedy). Handler will begin production today on the sitcom’s Burbank, CA. set.

Will & Grace is currently up for five Emmy nominations, including one for Megan Mullally (Karen Walker).

Season 2, which will feature 18 episodes, bows at 9 p.m. Thursday on Oct. 4. The series has already been renewed for an 18-episode third season.