LONDON — Credit Suisse reported a multibillion-dollar loss in the fourth quarter on Thursday — far more than analysts had expected and its largest in seven years — as turbulent markets and a substantial charge associated with its restructuring weighed on its results.

Shares of Credit Suisse declined as much as 12 percent in Zurich trading on Thursday as the bank posted a loss of 5.83 billion Swiss francs, or about $5.75 billion, in contrast to a profit of 691 million francs in the same quarter a year earlier.

The loss was largely because of a write-down of 3.8 billion francs after Credit Suisse reassessed the value of its investment bank as part of a continuing overhaul.

It was also the first annual loss for Credit Suisse since the bank reported a record loss of 8.2 billion francs in 2008. The Swiss lender’s results in 2008 were dragged down by a hefty trading loss in the fourth quarter and restructuring charges as it moved to cut about 11 percent of its work force.