CAIRO — At least nine people were killed when gunmen opened fire on a Coptic Orthodox Church in Cairo on Friday, a church spokesman said, in the latest in a series of attacks on Egypt’s Christian minority.

The assault targeted the Mar Mina Church in the southern Cairo neighborhood of Helwan. At least one gunman was killed by the police, the spokesman, Boules Haliem, said by telephone.

“He did not manage to get in,” Mr. Haliem said of the gunman. Worshipers were attacked as they were leaving the church, he said, and at least eight were killed, along with one police officer. Eight more worshipers and a police officer were wounded.

“The church was full,” Mr. Haliem said. “They were attending Mass.” Photographs showed several bullet holes in the facade of the church.