Nancy G. Brinker, the founder of Susan G. Komen for the Cure, will leave her post as chief executive, and its president will resign, the group announced on Wednesday in the most significant leadership shake-up to follow its short-lived attempt to cut financing for breast cancer services provided by Planned Parenthood.

In a statement, Komen called the changes “a new period of transition,” and said Ms. Brinker would move to a new management role focusing on revenue creation, strategy and global growth. Komen’s president, Liz Thompson, plans to leave in September, the statement said.

In a controversy that prompted the resignations of several senior executives, Komen announced in January that it planned to eliminate most financing for breast cancer education and screening by Planned Parenthood. Among its services, Planned Parenthood provides birth control and abortions, which several Komen executives opposed.

The decision provoked a national furor among abortion rights groups, forcing Komen to reverse itself. But doing so did not quell calls for a leadership shake-up that for many included Ms. Brinker’s resignation.