The University of Melbourne has the best reputation in Australia, according to a global ranking of the top 100 universities.

The university finished 41 in the Times Higher Education 2015 World Reputation Rankings, up from 43 the previous year.

Five Australian universities were included in the top 100. The Australian National University lifted its ranking from the 61-70 band to the 51-60 band, as did the University of Sydney. Monash University in Melbourne also regained a coveted spot in the top 100, finishing in the 91 to 100 group.

University of Melbourne acting vice-chancellor Professor Susan Elliott said the result was a wonderful endorsement and highlighted staff's strong international connections.

"We're pleased to again measure up so highly against some of the best institutions in the world. These results reflect a global awareness of the university's activity by many of our academic peers."

Times Higher Education Rankings editor Phil Baty said it had been a "strong" year for Australian universities. "This strong performance is testament to Australia's global higher education focus, crucial as the competition for international students hots up."

The index was based on a global survey of more than 10,507 senior academics in 142 countries. Academics were asked to nominate up to 10 of the best universities based on their experience and knowledge. Harvard University finished at the top.