by Andrew Potter

Jaguars Tight End James O'Shaughnessy -- Knee (IR)

James O'Shaughnessy, whose two touchdown receptions this season currently rank second on the Jaguars, suffered a clean tear of his ACL against the Panthers and will miss the rest of the season. A 2015 fifth-round pick by the Chiefs, O'Shaughnessy had started every game in this, his third season in Jacksonville. Offseason free-agent acquisition Geoff Swaim, formerly of the Cowboys, will probably see his playing time increase as a result. O'Shaughnessy should be healthy in time to begin next season, but he will probably miss a portion of the team's offseason work as he recovers from the injury.

Safety Ronnie Harrison injured his neck, and no further update is yet public.

Ravens Safety Tony Jefferson -- Knee (IR)

Ravens head coach John Harbaugh confirmed after Sunday's game that safety Tony Jefferson tore his ACL against the Steelers and will miss the rest of the season. Harbaugh also stated that Jefferson may have sustained additional damage, which will be investigated by MRI scan. Multi-ligament tears are not uncommon, and additional ligament damage could significantly impact Jefferson's recovery timeline. Jefferson still has a chance to be ready in time for the start of the 2020 season, but he is more likely to begin on the Reserve (Physically Unable to Perform) List.

Colts Defensive End Kemoko Turay -- Ankle (IR)

NFL.com reports that Kemoko Turay suffered a broken ankle while contributing to a sack of Patrick Mahomes on the Colts defense's final play from scrimmage against the Chiefs. Turay will miss the rest of the season, which usually signifies that the injury will require surgical repair. He should be able to return for the team's offseason program, but the former second-round pick will not play again this season.

Linebacker Zaire Franklin injured his hamstring. Most hamstring injuries to linebackers cause at least a one-game absence, but just under 75 percent return within two weeks.

Broncos Linebacker Justin Hollins -- Knee

Broncos Cornerback De'Vante Bausby -- Neck

Updates are already available on both of Denver's defensive injuries from their victory in Los Angeles. Linebacker Justin Hollins suffered an unspecified knee sprain. While the lack of specifics makes any prognosis uncertain, the most likely culprit is an MCL sprain, which would usually result in an absence of around five weeks for a linebacker. A milder sprain may enable a quicker return, possibly with the aid of a brace, but a November return sounds more likely.

Cornerback De'Vante Bausby left the game and was taken to hospital after a scary-looking friendly-fire neck injury. The Broncos have confirmed that he suffered a cervical sprain, and he was cleared to return to Denver with the team last night. As is sadly common among NFL injuries, this injury is more typically associated with car crashes (think whiplash) than athletic pursuits, and we therefore have no return-to-play data for it. At the very least, we expect him to miss the rest of October -- and perhaps significantly longer.

Bears Defensive Lineman Akiem Hicks -- Elbow

Akiem Hicks dislocated his left elbow when it was caught between teammate Khalil Mack and Raiders halfback Josh Jacobs while making a tackle. An MRI scan today will help to determine how much damage that dislocation has caused, and a timetable for his return. Most elbow injuries to defensive linemen are not quite this severe; around half of those that result in missed time cause an absence of four weeks or longer. Hicks' injury is most likely to fall among that number, but he should return sometime in November at the latest -- and perhaps by the end of October with the aid of a brace.

Packers Cornerback Darnell Savage -- Ankle

This is mainly a headline due to the sheer number of Packers injuries. Nevertheless, cornerback Darnell Savage suffered a high-ankle sprain against the Cowboys according to multiple reports. Those same reports suggest that the sprain is not major -- historically, that would be uncommon. More than 80 percent of high-ankle sprains to defensive backs cause a multi-week absence, and around one in three cause an absence of at least four weeks. Even a mild high-ankle sprain will probably keep Savage out at least until the October 27 visit to Kansas City.

Outside linebacker Za'Darius Smith injured his knee but is not expected to miss further time. Fellow linebacker B.J. Goodson injured his neck on special teams. Robert Tonyan injured his hip. No further update is yet available on the latter two.

The Kansas City Chiefs -- Various

Chiefs quarterback Patrick Mahomes aggravated his ankle injury against the Colts, but he is expected to continue playing through the pain. Defensive lineman Chris Jones is expected to miss time with a groin injury, but 75 percent of groin injuries to defensive linemen cause an absence of two weeks or less. That exact prognosis applies to the groin injury suffered by linebacker Anthony Hitchens and the hamstring injury to receiver Sammy Watkins. Defensive tackle Xavier Williams suffered a "badly sprained ankle" and awaits MRI results to help determine the duration of his absence -- around 60 percent of high-ankle sprains to defensive linemen result in an absence of four or more weeks. Finally, offensive lineman Andrew Wylie suffered a low-ankle sprain that is also expected to keep him out for a week or two. The next couple of weeks could see a shorthanded Chiefs gameday roster, but fortunately only one of the injuries is likely to linger much beyond that.

Concussions

The following players left their respective games with concussion symptoms and enter the league protocol:

Bengals receiver Alex Erickson

Bills offensive lineman Cody Ford

Giants halfback Wayne Gallman

Giants receiver Sterling Shepard

Packers center Corey Linsley

Steelers quarterback Mason Rudolph

Shepard's injury is particularly noteworthy as it is his second diagnosed concussion of the season. He was not diagnosed during the game, but showed concussion symptoms at the team facility on Monday morning. He is expected to miss substantially more time than is typical for a concussion diagnosis, as is common for a second diagnosed concussion of the season.

Based on our current data, a growing majority of players now miss at least one game following a diagnosed concussion, but around 80 percent return within two weeks.

Other Injuries

Bengals offensive lineman Andre Smith reportedly left Sunday's game with his foot in a protective boot, but he expects to play next weekend. Practice reports will either confirm or refute that optimism. Safety Shawn Williams injured his quad, but he also intends to play in Week 6. Here, at least, the optimism is justifiable -- barely a third of quad injuries to defensive backs result in even a single missed game.

Bills center Mitch Morse injured his ankle against the Titans and did not return to the game; however, he was on the sideline in full pads with his helmet, which suggests that he could have attempted to return if other injuries necessitated it. Morse had a pronounced limp after the game, but the injury does not appear serious enough to result in an extended absence.

Cardinals cornerback Tramaine Brock left with two separate injuries against the Bengals -- one to his knee, one his shoulder -- but no further specifics are yet available. Halfback David Johnson fought off pain in his back to finish the game, and is unlikely to miss significant playing time.

Chargers center Mike Pouncey left the game with an unspecified neck injury, and Anthony Lynn had no further update after the game. He was replaced at center by Dan Feeney, with Forrest Lamp taking Feeney's vacated left guard spot. No further update is yet available.

Cowboys right tackle La'el Collins left Sunday's defeat against the Packers with a knee injury, but the team is reportedly optimistic about the prognosis for both Collins and fellow tackle Tyron Smith. An MRI scan beckons for Collins, but he is not expected to miss significant time.

Eagles halfback Darren Sproles injured his quad against the Jets, but most quad injuries to running backs result in an absence of one week or less. Doug Pederson called Sproles "week-to-week" at his Monday press conference, but Sproles is not likely to miss more than one game.

Jets defensive lineman Henry Anderson is considered "week to week" with a shoulder injury, and he is not expected to play in Dallas in Week 6. The most likely culprit for a week-to-week shoulder injury is a sprain -- half such injuries to defensive linemen cause no absence at all, and more than 75 percent of players return within two weeks.

Panthers halfback Christian McCaffrey caused panic among fantasy owners when he left Sunday's game in the fourth quarter, but the Panthers have confirmed that he was merely suffering from cramps. He is not expected to miss any time.

Patriots receiver Phillip Dorsett injured his hamstring against Washington, making him very unlikely to play against the Giants on a shortened week. He is unlikely to miss much time beyond that, however; around 75 percent of receivers return from hamstring injuries within two weeks.

Redskins offensive tackle Donald Penn injured his hamstring against the Patriots. Around 50 percent of hamstring injuries cause offensive linemen to miss a game, but 75 percent return within two weeks.

Steelers receiver James Washington left the defeat against Baltimore with a shoulder injury and reportedly had his arm in a sling at the Steelers facility today. No specifics are yet public. If the injury is a sprain, the news is probably good: most shoulder sprains to wide receivers do not result in missed time, and 85 percent of players return within two weeks. If it is anything else, the news is less positive: a fracture or dislocation is far more likely to result in a long-term absence. Mike Tomlin usually provides injury updates later in the week. Linebacker Mark Barron injured his hamstring and is awaiting the result of an MRI scan. A plurality of hamstring injuries to linebackers cause an absence of one or two weeks.

Titans cornerback Chris Milton injured his calf against the Bills and did not return. Most calf injuries to defensive backs do not result in missed time, and over 85 percent of players return within two weeks.