Washington won the first matchup in Week 6 at FedEx Field, 27-20.

Now, the Redskins go for their fifth consecutive victory over the Eagles dating from December 2014.

Here are some of the key matchups to follow in this game:

Washington LT Trent Williams vs. Philadelphia DE Connor Barwin

The Redskins finally get their best offensive lineman – and one of their best players overall – back from a four-game suspension, which means Kirk Cousins will have the best possible protection on his blind side. The Redskins get back one of their emotional leaders as well. Williams faces off with Barwin, who ranks among Philadelphia’s leading pass-rushers with four sacks. Look for the Redskins to also run to Williams’s side a good bit as they work to find better balance on offense.

Washington ILBs, Will Compton, Su’a Cravens and Mason Foster vs. Philadelphia RBs Ryan Mathews and Darren Sproles

Leading rusher Ryan Mathews, who has missed the past two games with a knee injury, returns for Philadelphia. Without Mathews, the Eagles rushed for a combined 134 yards in the past two games. Sproles will remain the go-to option for the Eagles on passing downs. Sproles ranks second on the team with 47 catches and 452 yards. Washington’s defense, which has allowed an average of 122.5 rushing yards on the road, needs to do better. Look for Compton and Foster on rushing downs, and Cravens to enter on passing downs, where he’ll do his best to eliminate the threat that Sproles poses.

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Washington WR DeSean Jackson vs. Philadelphia CB Leodis McKelvin

The Redskins have started going deep to Jackson more often. He had a 67-yard touchdown catch the week before last and a 59-yard catch last week. However, Jackson wants more of those opportunities to take the lid off of the defense. McKelvin missed the Week 6 matchup, but the Eagles did a decent job of containing Jackson, limiting him to four catches for 55 yards, and a long of 35.

Washington OLB Preston Smith vs. Philadelphia LT Jason Peters

The Redskins badly need more from Smith, the second-year pro who has had one big game with two sacks and an interception, but in the other 11, has just 1.5 sacks. Smith will go up against 13-year veteran Jason Peters, and he’ll try to use his speed and athleticism to his advantage. There’s a lot of pressure on Washington’s defense after feeble outings the past two games. Look for the Redskins to really come after rookie quarterback Carson Wentz. In their first meeting of the season, Washington sacked him five times and held him to 179 yards passing, with no touchdowns.

Washington LG Arie Kouandjio vs. Philadelphia DT Bennie Logan

Left guard was a real problem area last week against the Cardinals. Coach Jay Gruden said on Wednesday that Shawn Lauvao revealed after the game that he was playing with an injured groin. Lauvao was on the sideline for practice early this week, and in his place was second-year pro Arie Kouandjio, who has been working and waiting for his opportunity. Kouandjio appears likely to start, and he’ll face an immediate challenge in Logan. Last game, right guard Brandon Scherff did a great job of neutralizing two-time Pro Bowler Fletcher Cox, so the Eagles could opt to flip Cox to the other side at times. Kouandjio will have his work cut out for him.

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Washington CB Josh Norman vs. Philadelphia WR Jordan Matthews

Matthews managed three catches for 75 yards on seven targets in his first meeting against the Redskins. He has an ankle injury that limited him in practice on Wednesday, but the Eagles hope that Wentz’s favorite target will be on the field Sunday. Norman will once again accept the challenge of neutralizing another top pass-catcher. For the season, Norman has played well, allowing 48 targets and producing 12 pass breakups, two forced fumbles and an interception.