We thank all of the subjects who participated in this study. We are grateful to A. Yoshida, K. Kano, S. Kawahara, R. Arita, K. Ishikawa, E. Hasegawa, R. Asato, S. Notomi, T. Asakuma and A. Kuni of the Kyushu University, K. Horie-Inoue, S. Inoue and T. Awata of the Saitama Medical University, H. Bessho, N. Kondo and W. Matsumiya of the Kobe university and M. Inoue of the Yokohama City University Medical Center for collecting samples. We thank the staff of the Laboratory for Genotyping Development, Center for Genomic Medicine, RIKEN, the staffs of the BioBank Japan project and the members of the Rotary Club of Osaka-Midosuji District 2660 Rotary International in Japan. We want to express special thanks to F. Miya for the support of gene expression data. This work was conducted as a part of the BioBank Japan Project and supported by the Ministry of Education, Culture, Sports, Sciences and Technology of the Japanese government.