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(CNN) Blood moon, Act II, opens soon in the heavens near you. And it will be bigger than Act I.

If you live in the western half of the United States, you'll have a front-row seat on a lunar eclipse that will turn the moon a burnt reddish orange for about an hour Wednesday, creating the second blood moon in relatively short succession.

The full eclipse will start at 6:25 a.m. ET, NASA says , and last until 7:24 a.m. ET.

Because it happens right after the perigee, the closest point to Earth in the moon's orbit, this blood moon will be nearly the size of a super moon -- appearing 5.3% larger than the previous blood moon on April 15

It will be the second in a sequence of four -- called a tetrad -- that are occurring in roughly six-month intervals. The next one will appear on April 4, 2015, and the last one on September 28, 2015.

Tetrad a rare treat

With that frequency, one might be misled into thinking that blood moons are commonplace.

There are about two lunar eclipses per year, NASA says. Some of them -- penumbral eclipses -- are so subtle, they are vaguely visible and go greatly unnoticed.

Other eclipses just cast a partial shadow on the moon but lend it none of that blood moon color that only total eclipses do. And they come around, on average, less than once a year.

The brilliant hue comes from the edges of the sun peeking out around the periphery of the Earth through its atmosphere in a global sunset shining on the moon, which has to be in just the right position to catch those rays.

Lunar eclipses -- penumbral, partial or total -- occur in random order, NASA says. Getting four total eclipses in a row is like drawing a rare lunar poker hand of four of a kind.

"The most unique thing about the 2014-2015 tetrad is that all of them are visible for all or parts of the U.S.A.," said NASA eclipse expert Fred Espenak.

NASA will guide the curious through the eclipse in a live chat on its website.

Photos: 2014 Photos: 'Blood moon' sweeps night sky Photos: 2014 Photos: 'Blood moon' sweeps night sky 'Blood moon' sweeps night sky – A "blood moon" rises over the El Salvador del Mundo monument in San Salvador early Tuesday, April 15, 2014, as a total lunar eclipse attracts sky gazers across the Americas. In a total lunar eclipse, the full moon turns a coppery red as it passes into Earth's shadow. "It's like seeing all the sunsets on Earth projected on the moon at once," says Indra Petersons of CNN's "New Day." Hide Caption 1 of 10 Photos: 2014 Photos: 'Blood moon' sweeps night sky 'Blood moon' sweeps night sky – The moon is seen from Miami before the beginning of the total lunar eclipse. The blood moon was most prominent in North and South America. Hide Caption 2 of 10 Photos: 2014 Photos: 'Blood moon' sweeps night sky 'Blood moon' sweeps night sky – Another shot from Miami. Showers and clouds rendered viewing the blood moon a bust in some U.S. cities. Hide Caption 3 of 10 Photos: 2014 Photos: 'Blood moon' sweeps night sky 'Blood moon' sweeps night sky – Dust and sulfur dioxide in the Earth's atmosphere can affect the size of the shadow spreading across the moon's surface. Hide Caption 4 of 10 Photos: 2014 Photos: 'Blood moon' sweeps night sky 'Blood moon' sweeps night sky – The moon has to be full for the total lunar eclipse to occur. Hide Caption 5 of 10 Photos: 2014 Photos: 'Blood moon' sweeps night sky 'Blood moon' sweeps night sky – The Earth's shadow crosses over the last bit of reflected light on the moon's surface. Hide Caption 6 of 10 Photos: 2014 Photos: 'Blood moon' sweeps night sky 'Blood moon' sweeps night sky – The moon begins to take on a reddish hue early Tuesday from Miami. The moon did so as it appeared in different phases between 2 and 4:30 a.m. ET. Hide Caption 7 of 10 Photos: 2014 Photos: 'Blood moon' sweeps night sky 'Blood moon' sweeps night sky – The red hue is caused by refracted sunlight in the Earth's atmosphere, which bounces off the moon while in shadow. The entire reddening process takes about an hour. Hide Caption 8 of 10 Photos: 2014 Photos: 'Blood moon' sweeps night sky 'Blood moon' sweeps night sky – The total lunar eclipse is seen in this image taken from Miami. Unlike solar eclipses, lunar eclipses are safe to view with the naked eye and don't require special filters. Hide Caption 9 of 10 Photos: 2014 Photos: 'Blood moon' sweeps night sky 'Blood moon' sweeps night sky – A lunar eclipse takes place over Southern California early Tuesday as seen from the San Gabriel Valley. North America will see a blood moon four times -- known as a tetrad -- between now and September 2015. Hide Caption 10 of 10

People in Europe, Africa and the Middle East will not be able to see Wednesday's blood moon.

In the 21st century, there will be many such tetrads, but look back a few centuries, and you'll find the opposite phenomenon, NASA says.

Before the dawn of the 20th century, there was a 300-year period when there were none, Espenak says. Zero.

That would mean that neither Sir Isaac Newton, Mozart, Queen Anne, George Washington, Napoleon, Abraham Lincoln nor their contemporaries ever had a chance to see such a sequence.

The stuff of mystics

There are those who like to veil these astral junctures in mysticism, and for them, the epilogue to Wednesday's celestial theatrics could sound like this:

Blood adorned a heavenly plate for Passover fest,

When sun and Earth aligned, a cooper glow to cast,

Upon the face of the moon as it did by Earth pass.

It shall again, to mark another holy rite, alas!

It's common to hang superstitions on blood moons , citing their concurrence with Jewish religious holidays.

The first one in this tetrad fell on Passover; the current one falls on the lesser known holiday of Sukkot , four days after Yom Kippur.

But that's no reason to go loony over cosmic coincidences -- because there are none here.

The Jewish calendar is an ancient lunar one, and holy dates are set, on purpose, to the precise clockwork of the moon's phases.

They're the same predictable ones that make it easy for modern-day astronomers to exactly calculate blood moons.