Two people are in hospital after an assault on one of Winnipeg's busiest streets early Wednesday morning.

A police spokesperson said officers were called to Main Street near Logan Avenue around 1:30 a.m. for a serious incident.

People in the area told CBC News they saw a fight start near the Manwin Hotel and continue to Logan Avenue.

The condition of the people in hospital isn't known. The spokesperson said more than one person is in custody, but couldn't say if they are suspects or witnesses.

Southbound Main Street reopened around 7 a.m. after it was closed between Higgins and Logan Avenues for the investigation.