Don’t be one of the great unwashed!

To protect yourself from being infected with coronavirus, the Centers for Disease Control and Prevention strongly recommends washing your hands often, scrubbing with soap and water for at least 20 seconds.

But not everyone at Penn Station got the memo.

Among the 519 people who used the men’s bathroom in the northwest corner of the massive transit hub over the course of an hour Thursday, 21 — or 4% — avoided soap and water.

The creepy culprits included a businessman, a hipster and an Amish man, who each ignored a pesky Post reporter confronting them about their hygiene habits.

A majority of the restroom visitors did their business at one of the 20 urinals and four stalls and then scrubbed their hands at one of the 12 working sinks as if they were about to go into surgery.

One went beyond the call of … doody. He washed his hands and then put on two blue latex gloves.

And then there was the soap skipper who blew his nose and then blew off a Post reporter.

“I washed my hands!” insisted one slippery stall visitor, who zipped his pants and left the restroom without lathering up, before joining his girlfriend.

“I rarely see people washing their hands,” a grossed out Jason Mason of Manhattan told The Post. “I just see people walking out. With coronavirus, you have to be on point — unless you want to die.”

Devout Hare Krishna Rama Roy, 61, who did the right thing in the restroom, repeated this pearl of wisdom by Ralph Kramden of “The Honeymooners”: “One hand washes the other while both hands wash the face.”