SAN FRANCISCO (MarketWatch) -- Five more bank failures brought the number of U.S. failures to 22 this year, the Federal Deposit Insurance Corp. said Friday. The two largest were Plantation Federal Bank of Pawleys Island, S.C., and Inter Savings Bank of Maple Grove, Minn., each with nearly $500 million in deposits. First Federal Savings and Loan Association of Charleston, S.C., will assume the deposits of Plantation Federal Bank, and Great Southern Bank of Reeds Spring, Mo., will assume the deposits of Inter Savings. HarVest Bank of Maryland in Gaithersburg will have its $145.5 million in deposits assumed by Sonabank of McLean, Va. The FDIC created the Deposit Insurance National Bank of Eastern Shore, which will remain open until May 25, so customers of failed Bank of the Eastern Shore of Cambridge, Md., can withdraw their insured deposits. Eastern Shore had about $154.5 million in deposits as of Dec. 31. The FDIC said Pacific Premier Bank of Costa Mesa, Calif., will take over operations of Palm Desert, Calif., National Bank. The Palm Desert bank as of Dec. 31 had $125.8 million in assets and $122.8 million in deposits. The cost to the FDIC Deposit Insurance Fund will be $20.1 million, the agency said.