Almost 50 trucks packed with more than 3,000 bales of donated hay and fodder will make their way across the Nullarbor from Western Australia this week, bound for drought-stricken farmers in New South Wales.

The 'Farmers across borders, hay from WA' convoy is the second from the group's organisers, who are based in the coastal farming community of Esperance.

Over the harvest, West Australian farmers baled hay and donated straw for the cause and on Tuesday, the convoy will leave Norseman, headed to the Cobar region of central-west NSW. It is due to arrive on Australia Day.

Sam Starcevich, a farmer from Salmon Gums in WA's south, is one of the coordinators of the mammoth hay run and helped to run a similar event in 2014, although on a much smaller scale.

She said having experienced drought herself as a farmer but now in better times, she wanted to take the near 3,000-kilometre trip to bring fellow primary producers hope and much-needed stock feed.

"Emotionally, drought is something you never get over, personally," she said.

"As soon as it doesn't rain you think, 'Oh my god, is it going to happen again? Is it not going to rain?' so it's always something there in your mind.

"And if this does something to ease a little bit of pain for someone, then we've done what we wanted to achieve.

"I think we're going to help between 300 and 400 farmers once we get to Cobar. Just from word of mouth I think that people are excited that we are coming."

The donated hay and fodder will help up to 400 farmers in New South Wales. ( ABC News: Tara de Landgrafft )

Mick Pratt, a transport operator from Albany in WA's south, is taking part in this year's mammoth hay run.

He said he missed the opportunity when the group did the 2014 run and wanted to make sure he was on board this time.

"I suppose it's an opportunity to give back," he said.

"People say it all comes one way, but no, it's an opportunity to help, which I think is great."

Each truck will have 60 to 70 bales of fodder on board and Mr Pratt said his two passengers did not mind how long it took them to get there and back because they would have to start school as soon as they returned.

"It will just be good for them to see, they're both at ag school at Denmark, and it will be good for them to see where things are a bit tougher and not quite so green," Mr Pratt said.

Ross Stone personally pressed thousands of bales of hay and straw for the donation.

He lost his farm to drought almost a decade ago and said he wanted farmers who were struggling to know that the nation was behind them.

Farmers Across Borders organiser Ross Stone wants to give back after himself experiencing drought. ( ABC News: Tara de Landgrafft )

"The last trip we did was so overwhelming and it's a bit personal for me, we've been through drought and had some tough times," he said.

"It's been a massive effort, especially when you've got another job.

"I was doing my other job, starting at 4 o'clock in the morning, loading log trucks and then in the afternoon, baling straw and doing that until midnight most nights and getting home again, getting a couple of hours' sleep and doing it all again."

He said he was very proud to see not just the local community, but the state's farmers and truck drivers get behind the cause, as well as businesses provide sponsorship.

But he said it was the help of his family that really made him smile.

"The kids are into it as much as I am, and the wife, they've all put their bit in and it's been great," he said.

"All of us together as a group decided that Australia Day was a good day just to show that Australians are out there to help other Australians.

"This will just buy those farmers a bit more time, maybe get a smile on their face."

While eastern Australia has experienced drought, farmers in Western Australia had one of their best seasons on record, with high yields in many areas and record grain prices.

Scaddan farmer Gavin Egan is taking part and hopes the hay will give drought-hit farmers some relief. ( ABC News: Tara de Landgrafft )

Scaddan farmer Gavin Egan said none of that is being taken for granted, which is why he is jumping in a truck this week to make the long drive across the big paddock.

"It's just helping out your fellow farmer," he said.

"No-one likes seeing anyone doing it tough. We've had it pretty tough in the past and we've had a pretty good year luckily.

"This is just a small amount that we can do to cheer someone up and maybe get them off to the beach for a week … if they know they've got more hay."