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WASHINGTON — Bernie Sanders will vigorously defend his signature “Medicare for All” proposal on Wednesday and hit back at his critics who say his push amounts to both bad politics and bad policy.

The Vermont senator also will pledge to reject campaign donations from health insurance and pharmaceutical industry executives, lobbyists and political action committees and will challenge other Democratic presidential candidates to do the same.

“You can’t change a corrupt system by taking its money.” — Sen. Bernie Sanders

“You can’t change a corrupt system by taking its money,” Sanders will say during a speech at George Washington University, according to prepared remarks.

The remarks come amid an intensifying fight among Democratic presidential candidates over how to best provide health care for Americans. It’s pitting Sanders, with his push for a single payer system of health insurance, against former Vice President Joe Biden, who is embracing a so-called public option that would give people the option of retaining private coverage.

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Sanders and Biden have been engaged in an increasingly bitter dispute over the issue in recent days and Wednesday’s speech could further escalate tensions between the two campaigns.

During a live-streamed discussion on Tuesday, Sanders dismissed Biden’s criticisms of Medicare for All and said the nation should have “a health care debate on the facts and not on fear-mongering.”

Biden Proposed Expanding the Affordable Care Act

“Medicare is a popular, well-established program,” he said. “All that we are doing, despite all that the health care industry is going to expend trying to lie about what we’re doing, what my opponents will talk about, all we’re doing is expanding Medicare. Not so radical really, after all.”

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Slipping in some public polling and outraised by some of his 2020 opponents, Sanders has been increasingly willing to go on the offense against Biden on the issue of health care, one that has sharply divided Democrats. Sanders’ campaign says that in the speech he will “confront the Democratic opponents of Medicare for All and directly challenge the insurance and drug industry” and will make the case that Medicare for All “is the only way to fix our broken health care system.”

On Monday, Biden released a proposal to expand the Affordable Care Act, warning that it would be dangerous to eliminate it and replace it with Medicare for All. Biden’s proposal would create a public option that would allow people to sign up for a government-run health system like Medicare if they were unhappy with private insurance.

This week in Iowa, where Biden pitched his plan to voters, he cautioned that a sudden transition of tens of millions of people to Medicare for All was “a little risky.”

Americans Still More Likely to Support ACA

He also raised the prospect that some people could see temporary gaps in coverage, a notion that Sanders has bristled at and called “obviously absurd.”

“I have helped write and defended the Affordable Care Act. But you know what? Times change, and we have got to go further.” — Sen. Bernie Sanders

On Tuesday, Sanders said the plan that Biden has pitched did not go far enough in ensuring that Americans have the coverage they need.

“I have helped write and defended the Affordable Care Act,” Sanders said during an interview with The Washington Post, which was live-streamed. “But you know what? Times change, and we have got to go further.”

Nine years after the Affordable Care Act was passed under the Obama administration, Americans are still more likely to support than oppose the law, 48% to 30%, according to an April poll from The Associated Press-NORC Center for Public Affairs Research, though a sizable share doesn’t take either side. Views of a single-payer health care system, in which all Americans would get their insurance from one government plan, are mixed: More Americans favor than oppose single-payer, 42% to 31%, and an additional 25% say they hold neither opinion.

Democratic Hopefuls Warn Party Is Moving Too Far Left

The roaring health care debate also is likely to further draw in the full Democratic field. Beyond Harris, several other leading 2020 candidates, including Massachusetts Sen. Elizabeth Warren, support Medicare for All. However, some other Democratic hopefuls have warned that the party is moving too far left and have supported a more centrist approach.

Among them is Colorado Sen. Michael Bennet, who has been sharply critical of Medicare for All, instead preferring a public option for health coverage that could be included in the current structure of the Affordable Care Act.

In an interview with The Associated Press as he campaigned in Iowa, Bennet said that Democrats would “never unify around Medicare for All” but that plans like his, which would create a public option but allow people to keep their private health insurance, could bring Democrats together and notch wins in states like Colorado.

“If you’re gonna stand up and commit the Democratic Party to taking away from 180 million people, you’d better be clear on what the nuances are because when you’re running against Donald Trump, it’s going to be too late,” he said. “You may think you can get away with it in the Democratic primary. You will not be able to get away with it running against Donald Trump.”