Andrew Wood is a former British ambassador to Moscow. His is an associate fellow of Chatham House's Russia and Eurasia program. The opinions in this article belong to the author.

(CNN) Russian President Vladimir Putin's hopes of a good relationship with Donald Trump had been fading for some time.

But Trump's airstrike last week on a Syrian airbase , followed by tough language from his top diplomats regarding Russia's support of the Syrian regime, suggests that Putin's options in Syria -- where he very recently was thought to hold all the cards -- are rather more limited than many previously thought.

Over the weekend, Secretary of State Rex Tillerson said that he hopes "Russia is thinking carefully about its continued alliance with Bashar al-Assad," while Trump's ambassador to the United Nations Nikki Haley has said that the US is "calling out" Russia and Iran in the aftermath of last week's chemical attack in Idlib.

In relation to Syria -- and perhaps more importantly, Ukraine -- any dreams Russia have had of brokering a grand bargain with the US are likely over. Moscow will now have to revisit its options on how, or whether, it cooperates with the US -- and these options are not as promising as is sometimes assumed.

Much will obviously depend on how US policy develops in Syria. But it's hard to see exactly what Russia can do next without making a bad situation worse.

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