Republicans are brushing off questions about their plan to run on tax cuts in November after the issue failed to gain traction in the Pennsylvania special election, which some are viewing as a troublesome sign for the party.

The Republican candidate, Rick Saccone, and allied conservative groups ran hard on President Trump Donald John TrumpBiden leads Trump by 36 points nationally among Latinos: poll Trump dismisses climate change role in fires, says Newsom needs to manage forest better Jimmy Kimmel hits Trump for rallies while hosting Emmy Awards MORE’s tax cuts before largely abandoning the message to pivot to immigration and attacking House Democratic Leader Nancy Pelosi Nancy PelosiAs families deal with coronavirus, new federal dollars should follow the student Sunday shows - Ruth Bader Ginsburg's death dominates Hypocrisy rules on both sides over replacing Justice Ginsburg MORE (Calif.).

While the final result of Tuesday's special election has yet to be certified, it appears Saccone has lost to Democrat Conor Lamb in a district that Trump carried by double digits in 2016.

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Democrats see big implications for the November midterms at a time when Republicans are signaling that the tax law will be one of their top talking points.

Senate Democratic Leader Charles Schumer Chuck SchumerRepublican senator says plans to confirm justice before election 'completely consistent with the precedent' Video of Lindsey Graham arguing against nominating a Supreme Court justice in an election year goes viral Graham signals support for confirming a Supreme Court nominee this year MORE (N.Y.) on Thursday held the Pennsylvania race up as proof that Republicans' claims about the popularity of the tax bill are overstated.

“The American people are smart about this,” he said on the Senate floor. “They know the vast majority of this goes to the wealthy. They know the amount going to them is small. They know that their tax breaks are temporary and corporate tax breaks are permanent.”

Schumer noted that two-thirds of the ads run by Saccone and super PACs backing him initially mentioned taxes. But after a week of testing this strategy, the percentage of ads focused on taxes dropped to 36 percent.

“After two weeks of these ads, they tested it out, my Republican friends. They got rid of taxes as an issue. It wasn’t working with the fairly well-off middle-class Pittsburgh suburbanites or blue-collar members of Green County and Westmoreland County,” he said.

Sen. Cory Gardner Cory Scott GardnerMcConnell locks down key GOP votes in Supreme Court fight Will Republicans' rank hypocrisy hinder their rush to replace Ginsburg? Jeff Flake: Republicans 'should hold the same position' on SCOTUS vacancy as 2016 MORE (R-Colo.), the chairman of Senate Republicans' campaign arm, shot back, arguing that Schumer's proposal to repeal the Trump tax cut in order to pay for infrastructure is a losing strategy.

"If I were Chuck Schumer Chuck SchumerRepublican senator says plans to confirm justice before election 'completely consistent with the precedent' Video of Lindsey Graham arguing against nominating a Supreme Court justice in an election year goes viral Graham signals support for confirming a Supreme Court nominee this year MORE, I'd be terrified about a growing economy with people earning wages that are higher than they were and I'd be terrified that I came up with a plan to increase taxes," he said.

Democrats nevertheless feel emboldened on taxes after Tuesday's results.

Lamb had called the tax bill signed into law by Trump in December a “giveaway” to wealthy individuals and large corporations while criticizing its impact on the national deficit.

“Taxes as an issue is substantially less salient among voters than many other things including and especially health care,” argued Geoff Garin, a Democratic pollster who briefed Senate Democrats last week on the Trump tax cuts.

“What Pennsylvania 18 shows is that when you have a real back-and-forth on the tax bill and the cost and consequences, it doesn’t stand up very well in the political battle of ideas and messages,” he said.

While Republicans are looking to highlight the issue, some vulnerable Senate Democratic incumbents also view the Trump tax cut as an opportunity to play offense.

“The public is starting to see that after blowing this huge hole in the budget, the Republicans are coming after Medicare, Medicaid and Social Security. There’s no doubt that they are,” said Sen. Sherrod Brown Sherrod Campbell BrownBipartisan praise pours in after Ginsburg's death Emboldened Democrats haggle over 2021 agenda Hillicon Valley: Russia 'amplifying' concerns around mail-in voting to undermine election | Facebook and Twitter take steps to limit Trump remarks on voting | Facebook to block political ads ahead of election MORE (D-Ohio), who is up for reelection in a state that Trump carried by 8 points.

Republican officials argue they fumbled the Pennsylvania seat, a district that Trump won a year ago in a landslide, because they had a weak candidate.

Corry Bliss, executive director of the Congressional Leadership Fund, called Saccone "a joke" after the election, while Trump had reportedly knocked the Pennsylvania Republican in private as "weak."

Speaker Paul Ryan Paul Davis RyanKenosha will be a good bellwether in 2020 At indoor rally, Pence says election runs through Wisconsin Juan Williams: Breaking down the debates MORE (R-Wis.) argued voters didn’t see Saccone as much more conservative than Lamb, who voiced support for expanded background checks instead of new gun restrictions and said he personally opposes abortion but supports the right to choose.

“They were able to pick a candidate who can run as a conservative,” Ryan said, noting that Lamb also said he wouldn't support Pelosi serving another term as Democratic leader.

Despite how the Pennsylvania race shook out, Republicans overall are leaning into the tax cuts as one of their best strategies come November, viewing it as a major accomplishment they can tout on the campaign trail while attacking vulnerable Democrats who opposed it.

Americans for Prosperity, a political group backed by billionaire donors Charles and David Koch, announced Wednesday it will spend $4 million on television and digital ads highlighting tax reform in Indiana and Missouri, two Senate battlegrounds.

The aggressive move forced Democrats to rally to the defense of Claire McCaskill Claire Conner McCaskillMomentum growing among Republicans for Supreme Court vote before Election Day Democratic-linked group runs ads in Kansas GOP Senate primary Trump mocked for low attendance at rally MORE (Mo.) and Joe Donnelly Joseph (Joe) Simon DonnellyNames to watch as Trump picks Ginsburg replacement on Supreme Court Momentum growing among Republicans for Supreme Court vote before Election Day Barrett seen as a front-runner for Trump Supreme Court pick MORE (Ind.), two other Democratic senators up for reelection in states Trump won.

Senate Majority PAC, a super PAC dedicated to winning a Senate Democratic majority, has spent $3.8 million in both states defending the incumbents.

Chris Pack, the communications director for American Crossroads and the Senate Leadership Fund, two outside groups dedicated to protecting the GOP majority, said Democrats wouldn’t have poured millions of dollars into Indiana and Missouri if they weren’t worried about the potency of taxes as an issue.

“If Democrats were truly unconcerned about tax cuts being used as an offensive message, then Donnelly would never have set up a microsite begging Senate Majority PAC to come in and defend him,” Pack said, referring to a page on Donnelly’s campaign website stating his support for middle-class tax cuts and his vote for extending the Bush-era tax cuts in 2012.

Chris Hayden, a spokesman for Senate Majority PAC, said his group is using a message similar to Lamb’s in Pennsylvania to defend McCaskill and Donnelly.

“When voters find out that their health care premiums are going up and the health care company got a huge tax break and this bill adds $1.8 trillion for the debt and they find out there’s a plan to change Medicare and Social Security to help pay for it, we do really well on the issue,” he said.

A senior Republican aide said the National Republican Senatorial Committee (NRSC) and allied groups are preparing more ads to attack Democrats for not backing the tax cuts.

“It is the clearest, easiest message,” the aide said. “This can be cut and played 18 different ways. We have so much information."

The NRSC blasted Sen. Bill Nelson Clarence (Bill) William NelsonDemocrats sound alarm on possible election chaos Trump, facing trouble in Florida, goes all in NASA names DC headquarters after agency's first Black female engineer Mary W. Jackson MORE (D-Fla.) for backing a proposal to repeal the Trump tax cuts to pay for an infrastructure bill. Nelson faces a tough reelection against a likely bid from Florida Gov. Rick Scott (R).

“Bill Nelson’s re-election strategy seems to be voting against bigger paychecks, bonuses and more jobs, and instead supporting higher taxes for Florida families,” said NRSC spokeswoman Katie Martin.

Meanwhile, Senate Majority Leader Mitch McConnell Addison (Mitch) Mitchell McConnellOcasio-Cortez to voters: Tell McConnell 'he is playing with fire' with Ginsburg's seat McConnell locks down key GOP votes in Supreme Court fight Video shows NYC subway station renamed after Ruth Bader Ginsburg MORE (R-Ky.) on Thursday highlighted other areas of the tax law where Republicans may focus, such as its expansion of the tax advantage for college savings accounts to allow families to use them for private and religious schools.

He said that helped one family in Louisville, Ky., send their learning-disabled child to a private school with smaller classes and more individual attention.

Garin, the Democratic pollster, argued that linking the rising profits of insurance and pharmaceutical companies — and rising costs for health-care consumers — to the tax bill is a strong strategy for Democrats.

“What we’ve been seeing in polling is that the biggest economic concern of voters is the high cost of health care and when you remind people that the tax bill gave huge benefits to drug companies and health insurance companies and those companies are going ahead and raising people’s health-care costs anyway, that’s a very powerful message,” he said.

Brown, meanwhile, is linking the tax cuts to Republican plans to reform entitlement programs as he gears up for a tough reelection fight in Ohio.

Ryan announced in early December that Republicans would aim to reduce federal funding on Medicare, Medicaid and entitlement programs, arguing that Medicare and Medicaid “are the big drivers of the debt.”

McConnell quickly dismissed the idea as a non-starter in the Senate, but Brown thinks it's still at the forefront of the GOP agenda.

“Of course they’re not giving up. They’ve never given up,” he said. “They don’t like social insurance. Anytime they’ve ever had a chance, they’ve gone after Medicare.”

“You saw Ryan did it right away. McConnell said no but McConnell has a three-times higher IQ when it comes to politics than Ryan,” Brown added.