A piece of Sydney's drinking history is set to disappear with the Alexandria Hotel marked for demolition.

At present, it's the de facto drinking headquarters for Sydney Swans fans.

The Alexandria Hotel in Alexandria has become a home away from home for Swans fans. Credit:Steve Lunam

A hotel has stood on the corner of Henderson Road and Garden Street in Alexandria since the late 1870s.

The existing building was built in the late 1920s and was operated by Tooth and Co.