Avondale FC's meteoric rise from suburban obscurity has continued with a 4-1 rout of Marconi to progress to the next round of the FFA Cup.

Based in Melbourne's north-west, Avondale were in the lowly sixth tier of Victorian football in 2009 but won promotion five times over the next six seasons to reach NPL1, the state's top league.

Fairytale run: Avondale FC celebrate their win after the FFA Cup Round of 32 match. Credit:AAP

They have now made their mark on the national stage at their very first attempt - against one of Australia's most illustrious clubs in Marconi, four-time champions of the National Soccer League.

Goals from Kane Sheppard, Joey Katebian, Liam Boland and Evan Christodoulou did the damage for the 'Avengers' in Wednesday night's round of 32 clash at ABD Stadium in Broadmeadows.