a, For each cell we computed the mean firing rate within individual motifs and calculated the mean of those values to obtain a single number for individual cells. Motif mean rates in VR (5.92±0.06Hz) were slightly smaller (10%, p = 7.7×10−10) than in RW (6.52±0.06Hz). b, Similarly, motif peak rates in VR (23.39±0.24Hz) were smaller (21%, p = 6.1×10−21) than in RW (28.32±0.69Hz). c, There was significant correlation between mean rate and the percentage of spikes that occurred within motifs in RW (r = 0.54, p = 4.1×10−65) and VR (r = 0.41, p = 1.2×10−28). This could explain the reduced motif duration and percentage of spikes contained in motifs in VR compared to RW (Fig. 5e). d, In both RW and VR, the percentage of spikes in motifs was significantly correlated with spatial information content of a neuron (RW r = 0.28, p = 4.2×10−17; VR r = 0.26, p = 6.5×10−12). e, Motif-field mean firing rates in VR (4.12±0.05Hz) were only slightly smaller (5%, p = 9.2×10−3) than in RW (4.34±0.05Hz). f, Motif-field durations in VR (1.33±0.01s) were similar but slightly reduced (10%, p = 1.1×10−12) compared to RW (1.48±0.01s). g, For cells active in both worlds on the same day, motif-field duration was correlated between RW and VR (r = 0.31, p = 1.2×10−3). h, Motif-field peak firing rate had a similar correlation (r = 0.54, p = 1.2×10−9). i, j,To estimate the percentage of spikes contained in motifs and motif durations, uninfluenced by the mean rate, we computed the Z-scored values for these two measures (see Methods). i, The Z-scored percentage of spikes in motifs was significantly above zero in VR (35.15±1.06, p=3.9x10-83) and RW (23.52±0.64, p = 1.0×10−26). In fact larger Z-scored values in VR indicate greater propensity for motif generation compared to RW. j, The Z-scored mean motif duration was indeed similar in both worlds (8.02±0.25 in RW and 7.33±0.27 in VR, p = 0.03) and greatly above zero (p = 2.1×10−96 and p = 1.4×10−83 in RW and VR respectively).