Joe Biden's son Hunter, 49, has reportedly split from his partner of two years Hallie Biden, 45, who was the widow of his late brother Beau.

The break-up comes on the heels of Joe Biden's highly anticipated presidential campaign announcement just last week.

In 2016 Biden said he didn't run for president because he was grieving over Beau's death and was notably mum on his son Hunter's tawdry affair that tarnished his family's wholesome reputation.

Hallie was the wife to Joseph 'Beau' Biden, the former Attorney General of Delaware and a major in the National Guard, until he tragically passed away at the age of 46 from brain cancer in 2015. The two share a son and daughter.

Two years after Beau's death in 2017, Hallie began to rub shoulders with Beau's lawyer younger brother Hunter and the two have remained a couple since.

When they met, Hunter was still married to his then-wife Kathleen, though they had been estranged. That divorce was finalized in April 2017.

Sources say that the break-up was 'amicable' but the reason behind the split remains unknown, according to Page Six.

Hunter Biden, 49, and Hallie Biden, 45, have reportedly broken up after two years together. The news comes just one week after Hunter's father Joe Biden announced he's running for president

Hallie was married to Beau Biden - former Vice President Joe Biden's elder son - when he passed away from brain cancer in 2015 at age 46 (pictured together in 2011). Then in 2017 she began to date Beau's brother Hunter

Earlier this year, Hunter opened up to Vanity Fair saying his personal life would not affect his father's White House bid.

'Even though my life has been played out in the media, because I am a Biden, my father never once suggested that the family’s public profile should be my priority. The priority has always been clear for my dad, as it is, now, for me: Never run from a struggle. Love people and find a way to love yourself,' he said.

'My father has always been proud of me — whether when I was volunteering for the Jesuits, or working as a lawyer . . . And he remains proud of me today. He loves me. And he loves the American people far too much to let any form of adversity stand in the way of service,' Hunter said in a statement in January.

Joe Biden has been incredibly public about his heartbreak over losing his son Beau to cancer, saying his grief kept him from running for president in 2016.

Speaking about his late son Beau on The View just last week, Biden choked on tears recalling his son's support of his career.

Hunter confirmed their relationship in 2017 saying, 'Hallie and I are incredibly lucky to have found the love and support we have for each other in such a difficult time, and that’s been obvious to the people who love us most'. Hunter and Hallie pictured together above

Hallie is pictured front standing next to Hunter Biden (left in blue suit and sunglasses) and Joe Biden (right in black) at Beau Biden's funeral in 2015

'He's not why I'm running... When I get up in the morning, I hope he's proud of me. I hope he's proud,' Biden said, adding his son urged him to run for president even on his deathbed.

'He said dad promise me, give me your word as a Biden, you will not back away. What he meant was, he knew I would always take care of the family to the best of my knowledge. But he didn't want me to withdraw from the things that motivated my whole life and trying to get engaged and change things and try to make things better,' said Biden, who titled a book on the subject, 'Promise me, Dad.'

Biden also shed tears when Beau placed his name into nomination for reelection at the Democratic National Convention in 2012.

'Four years ago, I told you that my father has always been there for me, my brother, and my sister, and that as vice president, he would be there for you. And he has,' Beau said praising his father.

Brothers: Hunter pictured left sitting with his brother Beau in 2012

Former vice president Joe Biden with his son Beau Biden in 2008

Joe and Jill Biden pictured talking about his presidential run on Good Morning America Tuesday

"I hope he's proud of me."@JoeBiden discusses his late son Beau: "He didn't want me to withdraw from the things that have motivated my whole life about trying to ... make things better." https://t.co/rxCXj3uvWG pic.twitter.com/HVA04j3AiW — The View (@TheView) April 26, 2019

When Hallie and Hunter became a couple following Beau's passing, the family stayed quiet.

In 2017 parents Joe and Jill Biden broke their silence and announced their support of the duo.

Who is Hunter Biden? Robert Hunter Biden, 49, is the second son of Joe Biden and his first wife Neilia Biden. He's a partner at Rosemont Seneca Partners LLC and is Counsel to New York law firm Boies, Schiller, Flexner LLP =. He started his career working in law and went on to work as a hedge fund manager and bank president He was appointed by Bill Clinton to serve in the U.S. Department of Commerce. In May 2013 he was selected as a direct commission officer in the U.S. Naval Reserve but was booted in 2014 after he tested positive for cocaine at the age of 44. He married Kathleen Buhle in 1993 and they share three daughters - Naomi, Finnegan and Maisy. They started living separately in October 2015 and divorced April 2017. He started dating his brother Beau's widow Hallie in 2017. Advertisement

'We are all lucky that Hunter and Hallie found each other as they were putting their lives together again after such sadness. They have mine and Jill’s full and complete support and we are happy for them,' they said.

Around the same time Hunter finally confirmed their relationship saying: 'Hallie and I are incredibly lucky to have found the love and support we have for each other in such a difficult time, and that’s been obvious to the people who love us most.'

'We’ve been so lucky to have family and friends who have supported us every step of the way,' he added.

The two have kept their relationship under wraps and have not been pictured in public together as a couple.

Hunter is a partner at Rosemont Seneca Partners LLC, which is run out of D.C.

He also served in the armed forces as a direct commission officer in the U.S. Naval Reserve in May 2013. He was ousted from the Navy reserve in February 2014 after he failed a drug test, testing positive for cocaine at the age of 44.

Hunter Biden's name also came up following the hack of the Ashley Madison extramarital affair website.

Conservative news site Breitbart reported in August 2015 that a Robert Biden (Hunter's given name) was found among hacked records, but Hunter denied it was his.

Beau Biden pictured celebrating his re-election for Delaware Attorney General with Hallie Biden at his side in 2010. In addition to his work in politics he was an Iraq vet

Family: Beau Biden pictured with Hallie and children Natalie and Hunter in 2010 in an official White House photo

Hunter pictured with his ex-wife Kathleen Biden in 2016. Their divorce was finalized in April 2017 and they had reportedly been living separately since 2015

Speaking on his divorce, Hunter says he has persevered thanks to the support of his father.

The life and legacy of Joseph 'Beau' Biden Joseph Robinette 'Beau' Biden was the eldest child of Joe Biden and his first wife Neilia Biden. He served as Attorney General of Delaware from 2007 to 2015. He joined the military in 2003 and was a Major in the Delaware Army National Guard. Biden was deployed to Iraq on October 3, 2008 and traveled back to Washington D.C. for his father's swearing in as Vice President in 2009. He ended his deployment in September 2009. For his service in Iraq he was awarded a Bronze Star and the Legion of Merit. He was posthumously awarded the Delaware Conspicuous Service Cross for 'heroism, meritorious service and outstanding achievement'. In May 2010 Biden was admitted to the hospital after suffering a mild stroke. In August 2013 he was diagnosed with brain cancer and passed away in May 2015. Advertisement

'The important aspect of my complicated divorce (like all divorces) and an equally complicated life, marked by the tragic loss of my mother, sister and brother, is this: My father has been a constant source of love and strength in my life,' Hunter said to Vanity Fair.

In that divorce Kathleen Biden cited irreconcilable differences due to how he spent 'extravagantly on his own interests (including drugs, alcohol, prostitutes, strip clubs and gifts for women with whom he has sexual relations), while leaving the family with no funds to pay legitimate bills.'

They share three children together.

Despite the family drama, Joe Biden, 76, has sealed his status as the Democratic front runner in the 2020 election, according to the latest poll as of Tuesday, leading against nearest rival Bernie Sanders by 24 points.

Biden capped off his first day on the campaign trail in Iowa where he made two speeches and an ice cream stop, touting his belief in former president Barack Obama's morals over Donald Trump's.

Biden announced his 2020 campaign on April 25 in a video citing the ideals of the founding fathers, condemning white supremacy, and slamming Donald Trump.

He called for 'equal opportunity, equal rights and equal justice.'