A couple from Maryland on vacation in the Dominican Republic were found dead in their hotel room.

Edward Nathaniel Holmes, 63, and Cynthia Ann Day, 49, had been staying at the Bahía Príncipe hotel at the resort Playa Nueva Romana since May 25, hotel complex director Francisco Romero told local media. After they missed their scheduled checkout time on Thursday, hotel staff entered the room and found both bodies unresponsive but no signs of violence, according to a statement from the hotel.

“We are deeply saddened by the incident at one of our hotels in La Romana, Dominican Republic, and want to express our deepest condolences to their family and friends,” the statement read. “The staff immediately contacted the relevant local authorities which have initiated an investigation.”

A spokesman for the Dominican Republic National Police told CNN blood pressure medication was also found in the room.

The couple’s bodies were transported to the Dominican National Institute of Forensic Sciences for an exam. An autopsy found they died of respiratory failure and pulmonary edema, which is caused by excess fluid in the lungs according to CNN.

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Officials with the U.S. Department of State confirmed the deaths and said they are in close contact with local authorities concerning the investigation.

Relatives told NBC4 that the couple from Prince George’s County were engaged. Holmes’ daughter Dajuan Holmes-Hamilton said she wants the case solved, the station reported.

"It should have never happened," she told the station.

The State Department issued a travel advisory for the country because of crime in April. While resort areas tend to be better policed that urban areas, “violent crime, including armed robbery, homicide and sexual assault, is a concern throughout the Dominican Republic.”

Just days ago, a Delaware woman said she was beaten unconscious while on a January vacation in the Dominican Republic. Tammy Lawrence-Daley told the Delaware News Journal that the attack nearly killed her and landed her in the hospital for five days.

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