I have loved science and medicine for a very long time – far longer than I have loved philosophy. Like most American kids, I didn’t even know what philosophy was until I set foot on a college campus. I was utterly seduced by every STEM class I took, and I bounced around from biology to computer science to physics and back to biology. In an alternate universe, I would have probably become a clinician. And then, one day, I found myself in a philosophy class. It was philosophy of medicine, and for the first time, I was pushed to think about medicine in a radically new-to-me way. Philosophy as a field is dedicated to questioning (and on a good day, answering) the foundational assumptions that dwell at the bottom of other inquiries. The field is not unified by subject matter so much as we’re unified by method. Our method is simple and unflinching: one’s claims demand justification.

As advancements and new technologies are rapidly emerging in health and medicine, there are an increasing number of ethical questions that arise. Dr. Tiffany Cvrkel is a bioethicist, philosopher, and lecturer in UCLA’s Molecular, Cell, & Developmental Biology department. In this week’s interview, she will teach us about the role bioethicists play in doctor and patient lives, and the importance of practicing correct bioethics in all aspects of medicine.

nature of health and disease and the purpose of medicine, and I had been taking them all on faith. I wanted to do better. I fell in love with the method, and changed my major to philosophy immediately. In graduate school, I focused on basic questions about praise, blame, and moral responsibility. Like science, ethics is broken down into several subfields. Bioethics is under the umbrella of applied ethics – the solving of particular problems as they exist in the world. My work in grad school was mainly in normative ethics – the theoretical underpinning of ethics. This divide between the applied and the normative is very similar to the divide between applied and basic/pure science. Just like the best applied science researchers have very solid grounding in basic science, I think so too do the best applied ethicists have very solid grounding in normative ethics.

What is the difference between ethics and morality, or making ethical vs moral decisions?

Ah, this can be a loaded question for an academic ethicist. These words are used in different technical ways by different disciplines. Somehow, a common-language notion of “morality” has emerged to mean something like “the beliefs that a culture or individual *actually* hold in regard to right and wrong” (or most/least important, or praise/blame-worthy – insert the particular content of your belief here).

Another way to capture this idea is to say that morality is descriptive. It refers to what people actually think or feel or belief. Ethics, on the other hand, typically refers to principles that exist independently (or outside) of what people believe. They are, on this usage, prescriptive – related to how people *should* act or value. I am not sure where these usages originated from, but it was certainly not from those of us who work in this field. Roughly speaking, here’s why. You might believe all kinds of things, for all kinds of reasons. You might believe the world is a week old, or that colds are caused by malicious spirits. And while some fields would be deeply interested in what you believe and how those beliefs developed (maybe psychology and/or anthropology?) your beliefs are not that interesting/helpful to scientists who want to figure out the truth about the age of the world or what causes colds. People in my line of work focus on what is true, not what people believe. We typically use these terms interchangeably to refer to the prescriptive idea, especially since people have been thinking and writing about these notions far longer than the English words have been around. If you read academic ethics, it is best to forget that other disciplines use these words in strange (to people like me!) ways.

Tell us about your current work in bioethics; How different do you think it will be in five years based on trends in science and bioethics?

I joke that my current work is about the very large and the very small. In particular, I am concerned with emerging technologies that allow us to make intentional changes to the germline of an embryo (the genetic information that will be passed on from generation to generation) – that is the very small part – and the developing marriage between medicine, research and Big Data – that is the very large part. These questions are representative of the greatest trend of medicine (and thus bioethics) in our immediate future. For many years, medical technology developed independently of many other forms of technology. We had people solving problems in separate but parallel platforms, and while there have been enormous advances in computing and data processing, those advances haven’t always been directly translated into patient-facing technologies. That is changing. Now, we’ve reached a point where technological advances in RFID might have applications in pacemakers, for instance. It is a very exciting time.

The practice of medicine is about science, yes. But it is also about relationships. We owe it to doctors to teach them these tools, alongside the rest of their training.

How does bioethics directly impact the lives of doctors and patients?

At the most basic level, bioethics helps create the best possible relationship between doctor and patient. Take medical decision making, for example. The patient comes to the doctor because he is in need of help that he is unable to provide for himself. The doctor has years of training and expertise, knowledge that the patient lacks. She knows what interventions statistically bring the best outcomes, at the general population level, but she is not an expert on the patient’s decision-making process. How risk-adverse is he? How might different complications affect him in particular? How is the patient supposed to know enough to ask about what he doesn’t know? We’ve moved past the days when doctors just did whatever they determined was best for a patient without a patient’s consent or input, and rightfully so. But how much information is the doctor supposed to give the patient before she receives genuine informed consent? What if the patient has an irrational fear of needles and refuses to get an infusion that might save his life? What should the doctor do? Bioethics can answer these questions. This field helps both doctors and patients navigate these interactions in respectful, productive, and ethical ways. The practice of medicine is about science, yes. But it is also about relationships. We owe it to doctors to teach them these tools, alongside the rest of their training.

What is an example of an important success story that bioethicists have had in medicine and healthcare in the past decade?

Here are a lot of bioethicists doing good work, but the first person who comes to mind with this question is the work that Margaret O. Little is doing at Georgetown. Little is a philosopher/bioethicist, and her recent work has focused on one of the most difficult and controversial bioethical areas: pregnancy, fetuses, and abortion. A great bioethicist looks at controversies that appear to be at stalemate and identifies how to resolve them. Typically, controversies like stem cell research are at stalemate because both sides are arguing with unfounded assumptions and unsupported rhetoric. They’re talking past each other. Breakthroughs happen when people identify the essential distinctions that have otherwise been missed. Little has so much good work – go read her whole body of writing if you have time! – but one of my favorite pieces of hers is her recent defense of a gradualist view of the moral status of embryos. Many of us have an intuition that an 8-cell pre-implantation embryo is importantly morally different than a 39 week old fetus. But not many of us can argue *why* this might be true. That is what Little does, and she does it beautifully.