York Regional Police have issued a Canada-wide warrant for a suspect in connection with the disappearance of Markham woman Ying Chun (Annie) Li.

Li, 36, was last seen by her family in Markham around 6 p.m. on June 12 in the area of Denison Street and Markham Road. She has not had contact with them since.

Early last month, the force announced that the homicide unit was taking over the investigation.

On Wednesday, police said that "as a result of the investigation police have reason to believe that Annie Li is deceased."

The York Regional Police homicide unit took over the case looking into the disappearance of Ying Chun (Annie) Li, last seen on June 12. (York Regional Police)

Investigators have issued a plea for the public's help to locate their suspect in the case. He is identified as Jiarui (Jerry) Tang, 21, of Toronto. He is known to frequent the Chinatown area of Toronto and is believed to be within the Greater Toronto Area.

"Mr. Tang is urged to seek legal counsel and turn himself in immediately," police said in a news release.

Police are urging members of the public not to approach Tang and to call 911 to report any sightings.

Anyone with information about the case is asked to contact the York Regional Police homicide unit at 866-876-5423 ext. 7865 or Crime Stoppers at 800-222-TIPS.