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Her response was clear: “Yes, yes, yes, yes, yes, yes, yes.”

“First of all, under Dodd-Frank, that is what will happen because we now have stress tests, and I'm going to impose a risk fee on the big banks if they engage in risky behavior, but they have to know, their shareholders have to know, that yes, they will fail and if they're too big to fail,” she explained.

“Then under my plan and others that have been proposed, they may have to be broken up.”

Clinton unveiled her Wall Street reform plan earlier this month, promising to tighten financial regulations.

The rest of Clinton’s interview with Colbert was not as wonky. Colbert brought up her birthday, which was Monday.

"Did you do anything special, like have a celebration for 11 hours?" the host asked, a reference to last week’s marathon hearing by the House Select Committee on Benghazi.

The candidate also discussed her favorite TV shows, including “House of Cards,” “The Good Wife” and “Madam Secretary.”

She is scheduled to appear on “Jimmy Kimmel Live” in November.