JERUSALEM  The collapse of Bernard L. Madoff’s $65 billion Ponzi scheme, whose victims included many American Jewish organizations and philanthropists, has also hammered a number of Israeli social service groups and wiped out at least three foundations that supported Israeli causes.

The aftershocks are still being felt here, but it appears that the scheme created losses in Israel amounting to at least hundreds of millions of dollars. It also damaged dozens of organizations, from the venerable matriarch of the American Zionist movement, Hadassah, whose hospital employees in Israel are taking pay cuts, to lesser known groups, like one that works with runaway Jewish and Arab teenagers and is weighing layoffs.

The Madoff scheme’s collapse has forced educational institutions and organizations that aid the sick and the needy to reassess their investment strategies, and Israel, which depends heavily on the nonprofit sector to provide such services, has been forced once again to confront its dependence on American donors’ largess.

The crisis “has exposed a very substantial weakness” among nonprofits here, said Eliezer Yaari, executive director of the New Israel Fund, an advocacy organization that promotes equality and social justice in Israel.