“Fear is freedom! Subjugation is liberation! Contradiction is truth! Those are the facts of this world! And you will all surrender to them, you pigs in human clothing!”—Satsuki addressing the students of Honnōji Academy

Satsuki Kiryūin (鬼龍院 皐月 Kiryūin Satsuki?) is one of the main characters in Kill la Kill. She is the president of Honnōji Academy's Student Council, and rules over the surrounding land. She has absolute authority over the academy and is regarded with reverence by many of its residents.

Although she was the main antagonist for the first half of the series with an anti-villain motive, she becomes a deuteragonist in episode 17 as her mother Ragyō Kiryūin takes the role of the antagonist for the remainder of the series.