Seven people died and five were in critical condition after the crash of a bus carrying tourists and local travellers in eastern Cuba.

State media reported the bus carrying 18 Cubans and 22 tourists crashed Thursday afternoon on a road between the cities of Baracoa and Guantanamo.

The names and nationalities of those killed haven't been officially released. According to a local media report, three of the deceased were from Cuba, two from Argentina, one from Germany and one from France.

A physician at a local hospital told CBC News that two Canadian men in their 50s have been treated for non-life-threatening injuries.

Dr. Iraima Cazull said one of the men suffered a minor head injury and the other required surgery for an arm tendon injury.

Global Affairs Canada said it was aware of reports of the crash and confirmed no Canadians were among those who died.

"Our thoughts are with all those injured and the loved ones of those who died in this tragic crash," the statement read. "We are providing consular assistance to Canadians who are affected."

Radio Guantanamo in Cuba reported that driver lost control on the wet and winding road.

Cuban highways are poorly lit, narrow and rutted with huge potholes.

There were 750 deaths and 7,999 injuries in 11,187 accidents last year in the country of 11 million.

Thursday's incident was the fourth major bus accident in a month.