Shift + F10 right-clicks.

Win + L (XP Only): Locks keyboard. Similar to Lock Workstation.

Win + F or F3: Open Find dialog. (All Files) F3 may not work in some applications which use F3 for their own find dialogs.

Win + Control + F: Open Find dialog. (Computers)

Win + U: Open Utility Manager.

Win + F1: Open Windows help.

Win + Pause: Open System Properties dialog.

Win + Tab: Cycle through taskbar buttons. Enter clicks, AppsKey or Shift + F10 right-clicks.

Win + Shift + Tab: Cycle through taskbar buttons in reverse.

Alt + Tab: Display Cool Switch. More commonly known as the AltTab dialog.

Alt + Shift + Tab: Display Cool Switch; go in reverse.

Alt + Escape: Send active window to the bottom of the z-order.

Alt + Shift + Escape: Activate the window at the bottom of the z-order.

Alt + F4: Close active window; or, if all windows are closed, open shutdown dialog.

Shift while a CD is loading: Bypass AutoPlay.

Shift while login: Bypass startup folder. Only those applications will be ignored which are in the startup folder, not those started from the registry (Microsoft\Windows\CurrentVersion\Run\)

Ctrl + Alt + Delete or Ctrl + Alt + NumpadDel (Both NumLock states): Invoke the Task Manager or NT Security dialog.

Ctrl + Shift + Escape (2000/XP ) or (Ctrl + Alt + NumpadDot) : Invoke the task manager. On earlier OSes, acts like Ctrl + Escape.

Print screen: Copy screenshot of current screen to clipboard.

Alt + Print screen: Copy screenshot of current active window to clipboard.

Ctrl + Alt + Down Arrow: Invert screen. Untested on OS’s other than XP.

Ctrl + Alt + Up Arrow: Undo inversion.

Win + B : Move focus to systray icons.

Ctrl + C or Ctrl + Insert: Copy.

Ctrl + X or Shift + Delete: Cut.

Ctrl + V or Shift + Insert: Paste/Move.

Ctrl + N: New… File, Tab, Entry, etc.

Ctrl + S: Save.

Ctrl + O: Open…

Ctrl + P: Print.

Ctrl + Z: Undo.

Ctrl + A: Select all.

Ctrl + F: Find…

Ctrl+W : to close the current window

Ctrl + F4: Close tab or child window.

F1: Open help.

F11: Toggle full screen mode.

Alt or F10: Activate menu bar.

Alt + Space: Display system menu. Same as clicking the icon on the titlebar.

Escape: Remove focus from current control/menu, or close dialog box.

Tab: Forward one item.

Shift + Tab: Backward one item.

Ctrl + Tab: Cycle through tabs/child windows.

Ctrl + Shift + Tab: Cycle backwards through tabs/child windows.

Enter: If a button’s selected, click it, otherwise, click default button.

Space: Toggle items such as radio buttons or checkboxes.

Alt + (Letter): Activate item corresponding to (Letter). (Letter) is the underlined letter on the item’s name.

Ctrl + Left: Move cursor to the beginning of previous word.

Ctrl + Right: Move cursor to the beginning of next word.

Ctrl + Up: Move cursor to beginning of previous paragraph. This and all subsequent Up/Down hotkeys in this section have only been known to work in Rich Edit controls.

Ctrl + Down: Move cursor to beginning of next paragraph.

Shift + Left: Highlight one character to the left.

Shift + Right: Highlight one character to the right.

Shift + Up: Highlight from current cursor position, to one line up.

Shift + Down: Highlight from current cursor position, to one line down.

Ctrl + Shift + Left: Highlight to beginning of previous word.

Ctrl + Shift + Right: Highlight to beginning of next word.

Ctrl + Shift + Up: Highlight to beginning of previous paragraph.

Ctrl + Shift + Down: Highlight to beginning of next paragraph.

Home: Move cursor to top of a scrollable control.

End: Move cursor to bottom of a scrollable control.

Arrow Keys: Navigate.

Shift + Arrow Keys: Select multiple items.

Ctrl + Arrow Keys: Change focus without changing selection. “Focus” is the object that will run on Enter. Space toggles selection of the focused item.

(Letter): Select first found item that begins with (Letter).

BackSpace: Go up one level to the parent directory.

Alt + Left: Go back one folder.

Alt + Right: Go forward one folder.

Enter: Activate (Double-click) selected item(s).

Alt + Enter: View properties for selected item.

F2: Rename selected item(s).

Ctrl + NumpadPlus: In a Details view, resizes all columns to fit the longest item in each one.

Delete: Delete selected item(s).

Shift + Delete: Delete selected item(s); bypass Recycle Bin.

Ctrl while dragging item(s): Copy.

Ctrl + Shift while dragging item(s): Create shortcut(s).

In tree pane, if any:

Left: Collapse the current selection if expanded, or select the parent folder.

Right: Expand the current selection if collapsed, or select the first subfolder.

Numpad Asterisk: Expand currently selected directory and all subdirectories. No undo.

Numpad Plus: Expand currently selected directory.