Notre Dame hosts USC in primetime on Saturday in the first and only night game at Notre Dame Stadium for 2019.

The Irish are coming off of a 52-0 blowout over Bowling Green, while the Trojans are coming off a bye week and hope to get second-stringer turned starting quarterback Kedon Slovis back in action. USC is undeniably talented (especially at wide receiver), but do oddsmakers think the Trojans can put together a strong enough performance to upset Notre Dame?

Odds via BetMGM. Access USA TODAY Sports’ betting odds for a full list. Lines last updated 10/7 at 12:45 p.m. ET.

Point Spread: Notre Dame -11.5 (-106), USC +11.5 (-115)

This is arguably the most interesting line on a Notre Dame game so far this season. It was odd, but not entirely unsurprising to see Georgia go from 12.5 to 15-point favorites over the course of that week, but this USC line is something else.

At some books, USC opened as a 10-point underdog, at others it opened down 13-points. Now the consensus has started to settle at 11.5, though the (-115) value on the USC spread indicates it could move from 11.5 to 11 even.

For context, the line on the Virginia game ended around 12.5 points, which Notre Dame covered in a 35-20 win. Do oddsmakers feel USC is better than No. 20 Virginia?

It is important to note that this is a rivalry game and these are 18-22 year-old kids. Anything can happen, and USC did beat then-No. 10 Utah with a third string quarterback.

Recent history gives little insight into the matchup. USC has not won in South Bend since 2011, but last year’s 5-6 Trojan team was a 14-point underdog against 11-0 Notre Dame and lost by only a seven points in Los Angeles.

Gannett may earn revenue from audience referrals to betting services. Newsrooms are independent of this relationship and there is no influence on news coverage.