Josh Reynolds is expected to play his first game in Wests Tigers colours this weekend after being given the green light to return from a hamstring injury against the Manly Sea Eagles.

Reynolds hasn't played a game this season after picking up an injury on the eve of his side's opening round clash against the Sydney Roosters.

Tigers coach Ivan Cleary will name Reynolds in his 21-man squad on Tuesday afternoon and will have to decide whether to start Reynolds on the bench or tinker with a winning formula.

Benji Marshall and Luke Brooks have been outstanding in the opening five weeks of the season, leaving Cleary with a huge decision to make ahead of the round six clash against Manly at Brookvale Oval.

Reynolds has spent some time at hooker previously, and Cleary had always planned to use him in the No.9 role at some point throughout the match before he got injured.

However he could also reshuffle his side and move Marshall back to the bench to accommodate the return of the club's marquee signing.

Lock Elijah Taylor has also been struggling with a hamstring injury and is unlikely to return in time for the match against Manly on Sunday afternoon.

The Tigers will also be without prop Russell Packer, who picked up a MCL strain in the victory against the Melbourne Storm in Auckland last week.

The Tigers originally feared Packer had suffered a season-ending injury, however scans later revealed he now faces a six week lay-off.