Republicans are needling Hillary Clinton Hillary Diane Rodham ClintonHillicon Valley: FBI chief says Russia is trying to interfere in election to undermine Biden | Treasury Dept. sanctions Iranian government-backed hackers The Hill's Campaign Report: Arizona shifts towards Biden | Biden prepares for drive-in town hall | New Biden ad targets Latino voters FBI chief says Russia is trying to interfere in election to undermine Biden MORE after she lost the New Hampshire Democratic primary to Bernie Sanders Bernie SandersMcConnell accuses Democrats of sowing division by 'downplaying progress' on election security The Hill's Campaign Report: Arizona shifts towards Biden | Biden prepares for drive-in town hall | New Biden ad targets Latino voters Why Democrats must confront extreme left wing incitement to violence MORE, her first defeat of the contest.

"No amount of spin can make up for such a crushing defeat in a state that has for decades been in the Clintons’ corner," said Republican National Committee Chairman Reince Priebus in a statement.

"The prospect that Democrats could nominate a self-avowed socialist is growing more probable by the day, and shows how off course Hillary Clinton’s coronation has gone," he added.

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The statement also tweaked Clinton by mentioning the FBI investigation of her email setup while secretary of State.

Multiple news outlets quickly declared that Sanders had won the Granite State primary shortly after polls closed at 8 p.m. on Tuesday.

Clinton's campaign had a concession prepared, which they released immediately. The memo said they were turning their focus to South Carolina and Nevada.

Sanders was widely expected to win Tuesday's contest in what has become a tougher-than-expected Democratic primary for Clinton. But Clinton's allies point to her strong leads in the next two states voting, where she has an edge with minority voters.

On the Republican side, outspoken billionaire Donald Trump Donald John TrumpHR McMaster says president's policy to withdraw troops from Afghanistan is 'unwise' Cast of 'Parks and Rec' reunite for virtual town hall to address Wisconsin voters Biden says Trump should step down over coronavirus response MORE was easily declared the winner of the New Hampshire primary, though the battle for second and third place has yet to be declared.

Democratic National Committee Chairwoman Debbie Wasserman Schultz (D-Fla.) congratulated Sanders for his win and also praised Clinton.

She also hit out at GOP winner Trump.

"Donald Trump started his campaign calling immigrants rapists and drug dealers, eventually called for banning members of an entire religion from entering America and recently said he would bring back interrogation techniques ‘a hell of a lot worse than waterboarding,'" the Florida representative said in a statement.

“Trump’s dominance over the Republican Party is a troubling development in our politics, but it also means the choice this November will be crystal clear."