Story highlights Hillary Clinton trails all of her Republican rivals in head-to-heads in Colorado, a new poll shows

Colorado is a key swing state in the presidential election

Washington (CNN) Colorado could be big trouble for Hillary Clinton.

The Democratic front-runner in the 2016 presidential race trails all the leading Republican contenders by 11 percentage points or more in the key swing state, a new Quinnipiac University poll shows

Florida Sen. Marco Rubio bests Clinton 52% to 36%, the biggest gap. Ben Carson wins a potential head-to-head matchup as well, with a 52% to 38% advantage. And Donald Trump leads 48% to 37%.

Tim Malloy, the assistant director of the Quinnipiac University Poll, described it as a "chilly if not frigid reception" in Colorado for Clinton.

In the nominating contest, Colorado's GOP voters' preference carries little weight. The party's caucus doesn't count because it violates Republican National Committee rules that require states to bind their delegates to the winners of their votes.

Read More