Brees set the NFL record for yards passing in a season, breaking a mark that Dan Marino had held for nearly three decades, and New Orleans clinched the NFC South title with a 45-16 victory over the Falcons.

Brees threw for 307 yards and four touchdowns, the last a 9-yard strike to Darren Sproles that set the record with 2:51 to go.

"Honestly, I was really trying not to think about the record or anything," Brees said. "I knew we were close. A couple guys mentioned stuff to me on the sideline. I didn't want to hear it. It's like a pitcher with a no-hitter, I guess."

It was Brees' final pass of the game and it gave him 5,087 yards passing -- with one game still to play. Marino finished with 5,084 yards for the Miami Dolphins in 1984.

Minutes after Brees broke the record, Marino offered congratulations on his Twitter account.

"Great job by such a special player," Marino wrote.

Brees responded in kind later, writing on his own Twitter account, "Thanks to @DanMarino for his class and support during this run. It is an honor to attempt to follow the example he set for us all."

As Sproles spiked the ball, Brees thrust his fist triumphantly in the air and started walking toward midfield while the Superdome crowd went wild and his teammates chased him down. Offensive lineman Carl Nicks was the first one to get there and tried to lift Brees onto his shoulder, but couldn't do it as teammates swarmed around.

"If I could have put him on my shoulders and paraded him around the whole stadium I would have done that. He deserves it," Nicks said. "It's like a movie, man. Just a movie ending. It's beautiful. ... You could tell by everyone's reaction after he did it how much people care about that guy. We all love him."

Brees' four touchdown passes gave him 276 for his career, moving him ahead of Joe Montana (273) and Vinny Testaverde (275) for ninth all-time. He is the first quarterback in NFL history to pass for more than 5,000 yards twice -- he had 5,069 in 2008.

Brees' first scoring pass went for 8 yards to Marques Colston and the second for 9 yards to Jimmy Graham. Graham's TD catch was his 10th of the season, a new franchise high for a tight end. In the third quarter, Brees hit Robert Meachem for a score from 24 yards, which made it 28-10.

"I love the fact that everybody could be part of this on Monday Night Football," Brees said. "There's so many people that are a part of this. It's not about me. It's about this team, it's about this city, it's about these fans. So many people contributed to this, and I'm happy for them."

The Saints also had 463 total yards, giving them more than 6,857 offensive yards for the season, breaking the 2008 club record of 6,571. New Orleans continues to close in on the NFL record of 7,075 offensive yards in a season set by the 2000 St. Louis Rams.

Brees might have broken the record in the third quarter if not for Sproles' 92-yard kickoff return, which set up John Kasay's 29-yard field goal. Brees also was intercepted twice, once in the Falcons end zone, but New Orleans was still dominant enough to take a three-score lead.