Story highlights Bus tour has planned stops in Pittsburgh, Pennsylvania, Columbus, Ohio and Charleston, West Virginia

Goal is to convince state senators to vote against the bill when it comes to the floor next week

Washington (CNN) Vermont independent Sen. Bernie Sanders will headline MoveOn.org's "Don't Take Our Health Care" bus tour this weekend, making stops in various East Coast states to challenge the newly released Senate health care bill.

With planned stops in Pittsburgh, Pennsylvania, Columbus, Ohio and Charleston, West Virginia, Sanders and leaders at MoveOn -- a progressive public policy advocacy group -- will speak at rallies urging GOP senators to save the Affordable Care Act and challenging Republican talking points that the alternative to Obamacare is a better option for Americans, according to Brian Stewart, director of media relations at MoveOn.

The tour is additionally designed to put pressure on the Republican senators in those states -- specifically, Sens. Pat Toomey of Pennsylvania, Rob Portman of Ohio and Shelley Moore Capito of West Virginia -- to vote against the Senate bill when it comes to the floor next week.

Sanders has called the Senate's health care bill "the most harmful piece of legislation" he's ever seen, and in the past warned that "thousands would die" if it passes.

"The Republican plan is even worse than expected and by far the most harmful piece of legislation I have seen in my lifetime," Sanders said in a statement provided to CNN. "This bill has nothing to do with health care. It has everything to do with an enormous transfer of wealth from working people to the richest."

Read More