Dozens of former senior members of Israel's defense establishment have published an open letter to Prime Minister Benjamin Netanyahu on Monday urging him to accept the nuclear accord with Iran as an "done deal."

The letter also called on Netanyahu and his government to renew the trust with the U.S. in order to prepare for the deal's challenges, and to "initiate a political move which will provide credibility to Israel's support of a two-state solution."

This, according to the letter, would enable the formation of a moderate Sunni-Western axis which will act against extremists in the region.

The letter was signed by former Shin Bet chiefs Amy Ayalon and Carmi Gillon, former MK Maj. Gen. (ret.) Amram Mitzna, Brig. Gen. (ret.) Shaul Arieli, former MK Roman Bronfman, former police chief Assaf Heffetz, among others.

"Such policies will enable both the integration of Israel's capabilities with those regional and international players who share the view of nuclear Iran as a serious threat, and the recruiting of moderate Arab states for the advancement of a political settlement between Israel and the Palestinians," read the letter.

The letter was published as an advertisement in the print edition of Haaretz on Monday, and was funded by the Blue White Future organization, which "seeks to help resolve the Israeli-Palestinian conflict on the basis of a 'two states for two peoples' solution by facilitating the relocation of settlers so that all Israel’s citizens reside within secure permanent borders that guarantee a Jewish majority," according to its website.

Netanyahu is set to address representatives from over 100 American Jewish organizations on Tuesday via an online video feed, hoping to influence Jewish communities to take a staunch public position against the deal with Iran.

The next day, Obama will speak at the American University in Washington, where 50 years ago, John F. Kennedy spoke in an effort to convince the American people that it was possible to prevent nuclear war with Russia through diplomacy. White House Press Secretary Josh Earnest said during a press briefing on Friday that the speech is meant to explain to the American people how the Iran deal serves U.S. security interests.

The letter, as will be published on Tuesday's English newspaper: