Newcomer Ashlee Evans-Smith has some big shoes to fill next month at UFC 181.

UFC officials today announced Evans-Smith (3-0 MMA, 0-0 UFC) has replaced injured Holly Holm (7-0 MMA, 0-0 UFC) and now meets fellow bantamweight Raquel Pennington (4-4 MMA, 1-1 UFC) at the event.

UFC 181 takes place Dec. 6 at Mandalay Bay Events Center in Las Vegas. The main card airs on pay-per-view following prelims on FOX Sports 1 and UFC Fight Pass.

Evans-Smith vs. Pennington is slated for the main card.

A neck injury sidelined Holm, a former pro boxer and highly touted UFC newcomer who recently said she doesn’t expect a lengthy recovery.

Evans-Smith turned pro in 2013 after a lengthy amateur career, and she’s 3-0 with two knockouts since then. The 27-year-old’s highest-profile win arguably came in October 2013, when she scored a ground-and-pound TKO victory over transgender fighter Fallon Fox to win a CFA tournament:

Most recently, Evans-Smith knocked out Marciea Allen at WSOF 10.

Pennington made her way to the UFC as a cast member on “The Ultimate Fighter 18,” where the 26-year-old served as a member of Miesha Tate’s squad. Pennington advanced to the semifinal round of the tournament before losing to Jessica Rakoczy. Pennington made her official UFC debut on the undercard of the show’s live finale, where she downed Roxanne Modafferi by decision. She then returned at March’s UFC 171 event, where she suffered a split-decision loss to Jessica Andrade.

The latest UFC 181 card includes:

MAIN CARD (Pay-per-view, 10 p.m. ET)

Champ Johny Hendricks vs. Robbie Lawler – for welterweight title

Champ Anthony Pettis vs. Gilbert Melendez – for lightweight title

Travis Browne vs. Brendan Schaub

Ashlee Evans-Smith vs. Raquel Pennington

Tony Ferguson vs. Abel Trujillo

PRELIMINARY CARD (FOX Sports 1, 8 p.m. ET)

Urijah Faber vs. Francisco Rivera

Eddie Gordon vs. Josh Samman

Corey Anderson vs. Jonathan Wilson

Todd Duffee vs. Anthony Hamilton

PRELIMINARY CARD (UFC Fight Pass, 7 p.m. ET)

Matt Hobar vs. Sergio Pettis

Clay Collard vs. Alex White

For more on UFC 181, check out the UFC Rumors section of the site.