Wheeler, 6-2, 245 pounds was originally selected by the Indianapolis Colts in the third round (93rd overall) of the 2008 NFL Draft out of Georgia Tech. Wheeler played in 61 games with 24 starts for the Colts, and recorded 141 total tackles (62 solo). In 2012, he was signed by the Oakland Raiders and started all 16 games, tallying 109 total tackles, three sacks and two forced fumbles. Wheeler spent the last two seasons with the Miami Dolphins, where he played in 31 games with 20 starts and posted 164 total tackles (118 solo).