Bruce Boxleitner began building his acting resume with TV appearances in the early 1970s, then secured his rise to stardom with a leading role in How the West Was Won in 1976. Regular work followed, including more starring roles in shows like Bring 'Em Back Alive, Scarecrow and Mrs. King, and Kenny Rogers' series of Gambler TV movies. In the early 1980s he also secured his place in sci-fi history with the dual roles of Alan Bradley and Tron in Tron, but another iconic piece of science fiction was yet to come.

Boxleitner took over command of Babylon 5 after the show's original star, Michael O'Hare, left the series due to health concerns after just one season. As Captain John Sheridan, he became a key figure in the show's overall mythology, and remained a part of the series until its conclusion.

Since then, Boxleitner has continued to work regularly. He reprised his roles as Alan Bradley and Tron in the sequel Tron: Legacy, and continued to provide the voice of Tron for the TV series Tron: Uprising. His most recent major TV work includes guest starring on NCIS and a long-running supporting role as the President on Supergirl. He can also be seen in the TV series Space Command.