In the show, Hunter and Bobbi Morse were essentially blacklisted from the spy world and were forced to go on the run. This was meant to set up their own spin-off Marvel's Most Wanted, but ABC ended up passing on the idea, and Hunter has not been seen since. The Framework would allow Hunter to return, albeit in a completely different form than what fans might recognize. Considering that this storyline is supposed to be very satisfying for longtime viewers of the show, and that the cast and crew could currently be working on the rest of the season, I'd say there's a very good chance we'll be seeing Hunter before Season 4 wraps.