Primary outcome: Favorable neurobehavioral outcome at 1 year, with secondary outcomes of survival at 1 year and change in neurobehavioral outcome.

Included: Post cardiac arrest kids, GCS < 5, intubated, received CPR > 2 mins, and got a return of spontaneous circulation (ROSC)

THAPCA-IH was halted for futility after enrollment of 59% of targeted patients because the primary outcome (favorable neurobehavioral outcome at 1 year) did not differ significantly between the TTM 32°C to 34°C (

, 48 of 133) and TTM 36°C to 37.5°C (

, 48 of 124) (RR 0.92% 95% CI 0.67–1.27;

P

= 0.63) groups. Secondary outcomes also did not differ between the two groups.