LOS ANGELES -- Stand Up To Cancer says its sixth celebrity-filled telethon was its most successful yet. The organization said Sunday that the fundraiser received more than $123 million in pledges from the U.S. and Canada.

Matt Damon, Tracee Ellis Ross, Jon Hamm and Winona Ryder were among the stars participating in Friday's telecast. Musical performers included Stevie Wonder, Little Big Town and Charlie Wilson, a cancer survivor.

Wonder paid tribute to Aretha Franklin, who died last month of pancreatic cancer, with a medley including "What the World Needs Now is Love" and "Love's in Need of Love Today."

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Bradley Cooper, whose father died of lung cancer, was co-executive producer of the telethon, which was carried commercial-free by major broadcast networks and cable channels in the U.S. and Canada and on streaming platforms.

Cooper said Stand Up To Cancer scientists are giving patients new hope they can become long-term survivors.

Little Big Town performs onstage at the sixth biennial Stand Up To Cancer (SU2C) telecast at the Barkar Hangar on Fri., Sept. 7, 2018, in Santa Monica, Calif. Getty

The telecast included three patients who have benefited from research funded by the group, including a former Marine Corps pilot with melanoma that spread to his brain and a retired school teacher with pancreatic cancer.

Stand Up To Cancer, a division of the philanthropic Entertainment Industry Foundation, was established in 2008 by media and entertainment leaders to accelerate research and get new therapies to patients quickly.

Among other achievements, it's funded research that has contributed to federal approval of five new cancer treatments, including for breast, ovarian, pancreatic and some difficult-to-treat leukemias, the group said.

Before the telecast, Stand Up To Cancer said Thursday said it has raised more $480 million to fund innovative research.

Others who took part in the event included organization co-founder Katie Couric, Mahershala Ali, Keith Urban, Josh Brolin, Julia Louis-Dreyfus, Ken Jeong, Matthew McConaughey, John Oliver, Marlon Wayans and Keanu Reeves.

A replay of the show is available online.