Re-elected Premier Daniel Andrews says he will offer Fiona Patten a job after her likely toppling in Saturday's election, describing her looming defeat as a 'loss to the Parliament'.

The Reason Party leader, who entered the upper house at the 2014 election as a member of the then-called Sex Party, looks set to be ousted by either Derryn Hinch Justice Party's Carmela Dagiandis or a Labor candidate in the Northern Metropolitan Region.

Fiona Patten says she has fallen victim to complex preferences deals. Credit:Wayne Taylor

When asked on ABC radio on Monday morning whether he would consider giving Ms Patten a job, Mr Andrews said there were many roles with the government that would suit her.

"I look forward to speaking with her personally in the next few days," he said.