
Thirteen of the 300-some American passengers evacuated from the Diamond Princess cruise ship that's been quarantined for two weeks in Japan are now back in the US, considered 'high risk' for coronavirus infection and undergoing treatment for the infection, with one confined to a special biocontainment unit in Nebraska.

Officials Monday morning confirmed that 14 of the passengers being evacuated to the U.S. had tested positive for coronavirus, but would still be allowed to fly back - in isolation chambers - on board the same planes as passengers who were negative for the virus.

About 10 of the 13 'high risk' patients have already tested positive for coronavirus, said officials in Nebraska, where 12 of the 13 passengers are now in isolation at the National Quarantine Unit in the Davis Global Center in Omaha - the only permanent federal quarantine facility in the US.

One passenger has been transported to the Nebraska Biocontainment Unit after the presented with a cough and lightheadedness after landing at Eppely Air Field. Local officials said that the person has a chronic health condition, but did not specify what sort.

The biocontainment unit at the University of Nebraska Medical Center is one of just three such facilities in the nation, deemed qualified to handle patients of the Ebola outbreak that infected 11 Americans in 2014.

All 13 high risk passengers will be re-tested stateside for coronavirus. Six were flown to Nebraska after landing at Travis Air Force Base in Northern California just before 11.30pm Sunday night and another seven were brought to the quarantine after landing at Lackland Air Force Base in San Antonio, Texas hours later.

It's not yet clear what type of 'care' the patients will receive while in isolation, although doctors in the US and abroad have been experimentally using antivirals, a drug designed to treat Ebola, supportive therapies (like IV fluids and ventilators) and, in China, plasma transfusions.

'Until we're done with testing they'll be self-isolated to their room,' said Shelly Schwedhelm, an official at the University of Nebraska Medical Center, of 12 quarantined patients in a press briefing.

It also remains unclear what protocols have been applied to the remaining patients who tested positive for coronavirus - about four - before taking off from Japan over the weekend to flee the ship where more 454 people have now become infected with the potentially deadly virus after another 99 cases were confirmed Monday.

The Nebraska Biocontainment Unit is one of just three in the U.S. that were designated equipped to contain and treat patients with Ebola during the 2014 outbreak that struck 11 Americans, including one, seen here being transported into the facility

Staff at the Nebraska Biocontainment unit practice placing a subject (an Air Force service member) in one of the specialized chambers that one of 13 evacuees from the Diamond Princess at 'high risk' of coronavirus was placed in after arriving at Eppely Air Field in Omaha on Monday. The other 12 patients are in quarantine

The 14 evacuees were placed in isolation chambers on-board their evacuation flights when officials realized they had tested positive for the deadly virus.

The first 747 plane touched down at Travis Air Force Base in Northern California just before 11.30pm on Sunday local time, before the second plane arrived at Lackland Air Force Base in San Antonio, Texas a few hours later.

The passengers had all been deemed 'fit to fly' and were not showing symptoms before disembarking from the cruise ship. As the evacuees were being taken to the airport in Tokyo, results from tests carried out two to three days earlier came back and showed the 14 passengers had the infection.

Despite the U.S. earlier saying no infected passenger would be allowed to leave, those who tested positive were still allowed to board the planes because they did not have symptoms. The State Department said they were being isolated separately from other passengers on the flights.

The U.S. said it arranged the evacuation because people on the Diamond Princess were at a high risk of exposure to the virus given more than 450 passengers have tested positive since the cruise liner was ordered to stay under quarantine on February 4.

As countries extricated their respective citizens from the cruise liner, which is by far the largest cluster of coronavirus cases outside China, some 3,000 people who have spent the last two weeks or more in a high risk environment fanned out across the globe.

Centers for Disease Control and Prevention (CDC) officials have warned that people can be asymptomatic, test negative for coronavirus and still develop later. They and World Health Organization (WHO) experts have also cautioned that even asymptomatic people can have and transmit the virus.

And that has some experts very worried.

'There's a possibility that anyone who is infected and asymptomatic could start a chain of infection wherever they return to,' Dr Stanley Deresinkski, a professor and infectious disease specialist at Stanford University told Fortune.

He was referring to passengers from the Westerdam cruise ship, currently in Cambodia but preparing to return home despite the fact that an 84-year-old American woman on board was diagnosed with coronavirus, but the same could certainly be true of the Diamond Princess, by far the largest cluster of coronavirus cases outside China.

A second plane carrying Americans evacuated from the Diamond Princess ship arrives at Joint Base San Antonio in Texas after flying back from Tokyo

One of two planes carrying 340 Americans back to the US from Japan where they spent almost two weeks under coronavirus quarantine on board the Diamond Princess cruise ship has landed at Travis Air Force Base in California (pictured)

The State Department confirmed that, after the evacuees had been placed on buses to the airport, 14 people who were not showing symptoms had tested positive for the virus - and were then placed into isolation chambers (pictured)

The sick passengers were allowed to continue on the flight but inside the isolation chambers (pictured), and will be taken for treatment separate to the other passengers after landing

340 Americans decided to abandon ship and take the government charter flights back to the US, where they will be under additional quarantine on two military bases for another 14 days

DIAMOND PRINCESS SAGA: TIMELINE OF CORONAVIRUS OUTBREAK February 4: Japan announced 10 people aboard the Diamond Princess cruise liner had been diagnosed with coronavirus. The ship, carrying more than 3,700 passengers, was placed under quarantine. February 15: U.S. authorities announced they would provide two planes to allow the 380 Americans on board the ship to return to the United States. February 16: Officials revealed 454 passengers were now infected on the ship, including about 62 Americans. Japanese authorities, dressed in head-to-toe protective suits, started transporting about 340 Americans to the airport in Tokyo on a convoy of 14 buses. As the evacuees were being taken to the airport in Tokyo, results from tests carried out two to three days earlier came back and showed the 14 passengers had the infection. Despite the U.S. earlier saying no infected passenger would be allowed to leave, those who tested positive were still allowed to board the planes in isolation because they did not have symptoms. February 17: The two planes touch down at Travis Air Force Base in Northern California and Lackland Air Force Base in San Antonio, Texas. All of the passengers must go through another 14 days of quarantine at the military facilities - meaning they will have been under quarantine for a total of nearly four weeks. February 19: The 14-day quarantine for the ship is scheduled to be lifted. Advertisement

Dr. Anthony Fauci, director of the National Institute of Allergy and Infectious Diseases at the National Institutes of Health, said Sunday that an infected person who shows minimal symptoms could still pass the virus to someone else.

It came as Japanese officials confirmed 99 additional people had been infected by the virus aboard the quarantined cruise ship, bringing the total to 454. At least 62 Americans are among those infected but it is unclear if that figure includes the 14 who were evacuated.

The United States was the first country to evacuate its passengers from the ship. Australia, Canada, Hong Kong and Italy were planning similar flights of passengers.

More than 73,000 people have now been infected with the virus worldwide, while 1,873 people have died from it. Overall, Japan has 419 confirmed cases of the virus, including one death. The United States has confirmed 15 cases within the country. Separately, one U.S. citizen died in China.

U.S. authorities had announced on Saturday that they would offer the 380 Americans on board the option to leave the ship. The evacuation was not mandatory but the Americans who chose not to leave the ship were warned they wouldn't be allowed to return to the U.S. 'for a period of time' that will be determined later by the Centres for Disease Control.

Those who arrived at Travis Air Force Base in California have been told they will be quarantined at the Westwind Inn on the base, which is the same place where those evacuated from Wuhan are being held. They will be kept in a separate part of the building to those who are already in quarantine.

The Americans who did evacuate the ship said they were frustrated about the additional two-week quarantine in the U.S. because they believed they would be able to walk free from the Diamond Princess when the ship's quarantine is scheduled to be lifted on Wednesday.

'It's like a prison sentence for something I did not do,' passenger Karey Mansicalco told CNN from her cabin. 'They are holding us hostage for absolutely no reason.'

'On cargo plane. You cannot Imagine. Crazy or worst dream ever,' American evacuee Gay Courter wrote on Facebook after boarding one of the flights at Tokyo International Airport.

Her husband Philip added: 'Huge windowless B-747 cargo plane with some seats bolted in. Destination unknown at this time.'

Americans Cheryl and Paul Molesky, a couple from Syracuse, New York, opted to trade one coronavirus quarantine for another, leaving the cruise ship to fly back to the U.S. Cheryl Molesky said the rising number of patients on the ship factored into the decision.

'We are glad to be going home,' Cheryl Molesky earlier told NHK TV in Japan. 'It's just a little bit disappointing that we´ll have to go through quarantine again, and we will probably not be as comfortable as the Diamond Princess, possibly.'

When they eventually boarded the plane with other Americans, Cheryl said: 'Well, we're exhausted, but we're on the plane and that's a good feeling. Pretty miserable wearing these masks though, and everybody had to go to the bathroom on the bus.'

Japan said that 340 Americans were taken to Tokyo's airport to be evacuated, while another those who had already been diagnosed were forced to stay behind for treatment. A handful of others opted to stay

Passengers on board the 747 cargo airplane could be seen taking pictures as they arrived back in America, having been held on the cruise ship since February 3

Buses carrying U.S. passengers who were aboard the quarantined cruise ship the Diamond Princess, seen in background, leaves Yokohama port, near Tokyo, early Monday. The cruise ship was carrying nearly 3,500 passengers and crew members

U.S. passengers from the Diamond Princess are seen on charter buses taking them to Haneda Airport on Monday

Passengers are seen boarding one of two planes bound for the U.S. at Tokyo's Haneda airport late Sunday after they evacuated the Diamond Princess cruise ship

A bus carrying U.S. passengers who were aboard the quarantined cruise ship the Diamond Princess arrives at Haneda airport in Tokyo, before the passengers board a Kalitta airplane chartered by the U.S. government

Other Americans on board the cruise ship declined to evacuate the Diamond Princess, despite being warned they will still have to wait two weeks and test negative for the virus before being allowed back to the United States.

They feared being on a long flight with other passengers who may be infected or in an incubation period.

'My health is fine. And my two-week quarantine is almost over. Why would I want to be put on a bus and a plane with other people they think may be infected when I have spent nearly two weeks isolated from those people?' Matt Smith, an American lawyer on the ship with his wife, tweeted.

He described a fellow American passenger standing on her balcony chanting 'USA, USA' as buses arrived to collect them.

'Of course, in contravention of the rules of quarantine, she's not wearing a face mask and she's talking with a passenger on the adjacent balcony... And you wanted me to get on a bus with her?'

He said American officials in hazmat suits and face masks had visited his room to check if he would disembark but he said he wanted to stay.

Later, when Smith had learned 14 infected passengers were still allowed to board the flights, he tweeted: 'OMG! US Gov't said they would not put anyone on the planes who was symptomatic, and they ended up knowingly and intentionally putting on 14 people who actually have the virus. Decision not to be evacuated = best decision ever!'

Japanese authorities, dressed in head-to-toe protective suits, helped transport the Americans to the airport in Tokyo on a convoy of 14 buses.

Americans Cheryl and Paul Molesky, a couple from Syracuse, New York, said after boarding the flight: said: 'Well, we're exhausted, but we're on the plane and that's a good feeling. Pretty miserable wearing these masks though, and everybody had to go to the bathroom on the bus.'

Americans who evacuated the cruise ship are pictured boarding one of the two planes that took them back to the U.S.

Those Americans who chose to leave the Diamond Princess are seen in a chartered evacuation aircraft to fly back to the US

Phil Courter, a U.S. passenger on board the Diamond Princess cruise ship, wears a face mask on a chartered evacuation aircraft to fly back to the United States at Haneda airport in Japan

Health officials in protective suits are seen ferrying passengers to board the evacuation flights in Tokyo

American Sarah Arana, a 52-year-old medical social worker, said there were no health checks when they passed through a makeshift passport control.

She said the U.S. government should have acted 'much sooner, at the beginning'.

'I am happy and ready to go,' Arana told AFP before leaving the ship. 'We need a proper quarantine. This was not it.'

Across mainland China, officials said the total number of coronavirus cases rose by 2,048 to 70,548. That was slightly more new cases than were reported on Sunday, but hundreds fewer than reported on Saturday.

Chinese authorities say the stabilisation in the number of new cases is a sign that measures they have taken to halt the spread of the disease are having an effect.

However, epidemiologists say it is probably still too early to say how well the outbreak is being contained within China and its central Hubei province, where the virus first appeared.

China has responded to the COVID-19 virus by effectively locking down Hubei's provincial capital Wuhan, a megacity of 11 million people.

Medical workers in protective suits attend to a patient inside an isolated ward of Wuhan Red Cross Hospital in Wuhan, the epicentre of the novel coronavirus outbreak

Medical staff members treating a patient infected by the COVID-19 coronavirus at the Wuhan Red Cross Hospital in Wuhan in China's central Hubei province

Did coronavirus originate in Chinese government laboratory? Chinese scientists believe the coronavirus may have started life in a research facility just 300 yards from the Wuhan fish market. A new paper from the Beijing-sponsored South China University of Technology says the Wuhan Center for Disease Control (WHCDC) could have spawned the contagion in Hubei province. The paper, penned by scholars Botao Xiao and Lei Xiao, claims the WHCDC kept disease-ridden animals in laboratories, including 605 bats. It also mentions that bats - which are linked to coronavirus - once attacked a researcher and 'blood of bat was on his skin.' The report says: 'Genome sequences from patients were 96% or 89% identical to the Bat CoV ZC45 coronavirus originally found in Rhinolophus affinis (intermediate horseshoe bat).' It describes how the only native bats are found around 600 miles away from the Wuhan seafood market and that the probability of bats flying from Yunnan and Zhejiang provinces was minimal. In addition there is little to suggest the local populace eat the bats as evidenced by testimonies of 31 residents and 28 visitors. Instead the authors point to research being carried out withing a few hundred yards at the WHCDC. One of the researchers at the WHCDC described quarantining himself for two weeks after a bat's blood got on his skin, according to the report. That same man also quarantined himself after a bat urinated on him. He also mentions discovering a live tick from a bat - parasites known for their ability to pass infections through a host animal's blood. 'The WHCDC was also adjacent to the Union Hospital (Figure 1, bottom) where the first group of doctors were infected during this epidemic.' The report says. 'It is plausible that the virus leaked around and some of them contaminated the initial patients in this epidemic, though solid proofs are needed in future study.' Advertisement

Concerns remain about the global transmission, especially on cruise ships which appear to have become especially virulent breeding grounds.

Fears are growing for passengers on the Westerdam cruise ship, who all received a clean bill of health when they disembarked in Cambodia - a staunch ally of Beijing.

An 83-year-old American woman was stopped by authorities in Malaysia over the weekend when she was detected with a fever and later diagnosed with the virus.

There were more than 2,200 passengers and crew on the ship when it docked in Sihanoukville, many of whom have now dispersed around the globe.

With tourism battered and global supply chains disrupted by the virus, experts are fretting about the toll it could take on a fragile global economy.

IMF chief Kristalina Georgieva said there could be a cut of around 0.1-0.2 percentage points to global growth but stressed there was 'still a great deal of uncertainty.'

Japan, one of the hardest-hit countries outside China irrespective of the Diamond Princess, suffered its biggest economic slump in more than five years - even before the coronavirus crisis. Gross domestic product in the world's third-top economy shrank an eye-watering 1.6 percent in the three months to December - a much bigger contraction than economists had feared.

It comes after Chinese scientists revealed the deadly virus may have started life in a research facility just 300 yards from the Wuhan fish market.

A new bombshell paper from the Beijing-sponsored South China University of Technology says that the Wuhan Center for Disease Control (WHCDC) could have spawned the contagion in Hubei province.

'The possible origins of 2019-nCoV coronavirus,' penned by scholars Botao Xiao and Lei Xiao claims the WHCDC kept disease-ridden animals in laboratories, including 605 bats.

It also mentions that bats - which are linked to coronavirus - once attacked a researcher and 'blood of bat was on his skin.'

The report says: 'Genome sequences from patients were 96% or 89% identical to the Bat CoV ZC45 coronavirus originally found in Rhinolophus affinis (intermediate horseshoe bat).'