TEHRAN — The chants of “Death to America” and the burning of American flags in the streets are as familiar a part of life here as air pollution and traffic jams. With the United States and Iran on the verge of a potentially historic nuclear accord, however, there has been a distinct change in tone: the anti-Americanism is getting even more strident.

The rising levels of vitriol have been on display this week in the buildup to the annual anti-Israel extravaganza coming this Friday.

“We march not only against Israel,” the influential Ayatollah Ali Jannati told the Fars news agency of the annual rally on the last Friday of Ramadan in Iran and other Muslim countries. “It goes far beyond that. We also march against the arrogant powers,” Europe and, particularly, the United States.