A woman in her 50s is dead after she was struck by a driver, who then left the scene in York overnight, according to Toronto police.

The collision occurred shortly before 1 a.m. Thursday on Eglinton Avenue near Marlee Avenue, just west of Allen Road.

The woman was taken a downtown trauma centre but died of her injuries shortly after, police said.

Const. Clint Stibbe, of Toronto police's traffic services, said that investigators don't have information on the vehicle or driver.

"There's been no confirmation as to the type of vehicle or any sort of identifying features of the vehicle that struck her at this point," Stibbe told CBC Toronto.

Officers are canvassing the area for any security cameras that may have captured the collision.

Stibbe appealed for anyone with potentially useful information to contact police.

"We need the publics help in this case, because we have nobody who can tell us definitely who, or what, struck this woman."

A post mortem examination is scheduled for the coming days, and Stibbe said it may provide some clues as to what type of vehicle was involved.

Eglinton Avenue was closed in both directions from Alameda Avenue to Winona Drive for several hours, but it has since reopened to traffic.