In the beginning, Mark Burnett made a name as the most prominent producer of reality television. Now he’s moving from Omarosa to Moses.

In what Mr. Burnett is calling the “most important project I have ever undertaken,” he has made a deal with the History Channel to mount a 10-hour series based on the stories of the Bible. The project, which History will announce on Tuesday, is expected to be on a similar scale to its most ambitious work, “America: The Story of Us.”

That 12-part series, covering the 400-year history of America and broadcast last year, was closer to the fare typically seen on the History Channel. But Nancy Dubuc, the president of History, said the historical importance of the Bible is beyond dispute.

“This is the most discussed, debated book in the history of mankind,” said Ms. Dubuc, whose channel has tackled other religious projects, like “Jesus: The Lost 40 Days” and “The Real Face of Jesus?”