President Trump Donald John TrumpOmar fires back at Trump over rally remarks: 'This is my country' Pelosi: Trump hurrying to fill SCOTUS seat so he can repeal ObamaCare Trump mocks Biden appearance, mask use ahead of first debate MORE’s latest shot in the culture war appeared to backfire Wednesday, as Republicans distanced themselves from comments he had made at a rally the previous evening.

The president, speaking in Southaven, Miss., on Tuesday mocked Christine Blasey Ford, who has accused Supreme Court nominee Brett Kavanaugh of sexual assault.

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Trump, to the crowd’s apparent delight, scorned Ford’s inability to remember details surrounding the alleged incident, which she says happened at a Maryland house party in 1982 when she and Kavanaugh were high school students.

Kavanaugh denies the allegations, and the political world has been dominated by claim and counter-claim since the two testified separately before the Senate Judiciary Committee last Thursday.

But Trump’s decision to up the ante by openly deriding Ford drew criticism even from some members of his own party.

“We’re in a very familiar place, where he says something that is obviously outrageous that doesn’t help his cause at all,” said Doug Heye, a GOP strategist and a former communications director of the Republican National Committee.

Trump has been willing to stoke hot-button issues since he began running for the presidency.

Attacks on the late Sen. John McCain John Sidney McCainCindy McCain endorses Biden: He's only candidate 'who stands up for our values' Biden says Cindy McCain will endorse him Biden's six best bets in 2016 Trump states MORE’s (R-Ariz.) time as a prisoner of war, on Gold Star parents who appeared at the Democratic National Convention, and on a judge of Mexican parentage, were all predicted, wrongly, to have disastrous effects on his electoral chances.

In the White House, he has frequently fanned the controversy over NFL players “taking a knee” during the national anthem to protest racial injustice and police brutality — and has suffered no clear detrimental effect on his political fortunes for doing so.

But this time could be different, critics say, in part because Kavanaugh’s confirmation is far from certain. Three moderate Republican senators hold the judge’s fate in their hands, and Senate Majority Leader Mitch McConnell Addison (Mitch) Mitchell McConnellPelosi: Trump hurrying to fill SCOTUS seat so he can repeal ObamaCare Senate GOP aims to confirm Trump court pick by Oct. 29: report Trump argues full Supreme Court needed to settle potential election disputes MORE (R-Ky.) insists a vote must happen soon.

All three undecided Republicans — Sens. Susan Collins Susan Margaret CollinsSenate GOP aims to confirm Trump court pick by Oct. 29: report The Hill's Campaign Report: GOP set to ask SCOTUS to limit mail-in voting Senate GOP sees early Supreme Court vote as political booster shot MORE (Maine), Jeff Flake Jeffrey (Jeff) Lane FlakeJeff Flake: Republicans 'should hold the same position' on SCOTUS vacancy as 2016 Republican former Michigan governor says he's voting for Biden Maybe they just don't like cowboys: The president is successful, some just don't like his style MORE (Ariz.) and Lisa Murkowski Lisa Ann MurkowskiSenate GOP aims to confirm Trump court pick by Oct. 29: report Senate GOP sees early Supreme Court vote as political booster shot Pence defends Trump's 'obligation' to nominate new Supreme Court justice MORE (Alaska) — were critical of the comments Trump made at the Mississippi rally.

Collins referred to them as “just plain wrong,” Flake as “kind of appalling” and Murkowski as “wholly inappropriate” and “unacceptable."

There was even criticism from some figures more closely allied with Trump and Kavanaugh.

Sen. Lindsey Graham Lindsey Olin GrahamSenate GOP aims to confirm Trump court pick by Oct. 29: report The Hill's Campaign Report: GOP set to ask SCOTUS to limit mail-in voting Senate GOP sees early Supreme Court vote as political booster shot MORE (R-S.C.), who has been one of Kavanaugh’s staunchest defenders, said during an appearance Wednesday at a conference organized by The Atlantic, that he would tell Trump to “knock it off — it’s not helpful.”

The danger, from a center-right perspective, is that the incendiary nature of Trump’s comments raise the political price that Collins and Murkowski might have to pay for supporting Kavanaugh in a final Senate confirmation vote. Flake, unlike the other two, is retiring from the Senate and is therefore liberated from any calculations about his reelection chances.

Still, some supporters of the president insist that the chances of Kavanaugh’s confirmation failing because of Trump's comments are being exaggerated.

Brad Blakeman, a veteran of President George W. Bush’s White House, insisted that the confirmation process “isn’t about Donald Trump, it’s about Brett Kavanaugh.”

Referring to the Republican senators whose votes are still up for grabs, he argued that Kavanaugh should be confirmed on his own merits.

“The fact is, they are not going to vote against Brett Kavanaugh because the president has made statements that make them uncomfortable,” he insisted.

Some in the GOP also believe that any lawmaker within the party who opposes Kavanaugh will face political consequences. They note that conservative voters backed the president in 2016, despite his own colorful personal history, in part because they believed he would get conservatives onto the high court.

On the other side of the aisle, Democrats blame Trump for a tone of callousness and dismissiveness that they view as inappropriate for a commander in chief.

Speaking to MSNBC’s Ari Melber on Wednesday evening, Sen. Ben Cardin Benjamin (Ben) Louis CardinCongress must finish work on popular conservation bill before time runs out PPP application window closes after coronavirus talks deadlock Congress eyes tighter restrictions on next round of small business help MORE (D-Md.) accused the president of seeking to make the confirmation process a partisan endeavor.

Trump’s rally comments, Cardin said, were “horrible, they should have no place in American politics…It was just disgusting.”

Sen. Kamala Harris Kamala HarrisButtigieg stands in as Pence for Harris's debate practice First presidential debate to cover coronavirus, Supreme Court Harris joins women's voter mobilization event also featuring Pelosi, Gloria Steinem, Jane Fonda MORE (D-Calif.), a possible 2020 presidential candidate, lambasted Trump during an interview at the Atlantic conference for “urging a crowd to laugh at [Ford]” while speaking from the stage at a political rally.

“I’m embarrassed that the president of the United States would do that to this woman,” Harris added.

The White House has closed ranks around the president, with press secretary Sarah Huckabee Sanders and senior counselor Kellyanne Conway Kellyanne Elizabeth ConwaySpecial counsel investigating DeVos for potential Hatch Act violation: report George and Kellyanne Conway honor Ginsburg Trump carries on with rally, unaware of Ginsburg's death MORE both defending his remarks.

But in the broader Republican Party, there is consternation that the president would risk alienating female voters, in particular, at a time when polls are already showing erosion in the party’s support with women.

“It causes further anger to white, suburban, college-educated women who, to put it mildly, have been skeptical of Trump,” said Heye.

Sen. Orrin Hatch Orrin Grant HatchBottom line Bottom line Senate GOP divided over whether they'd fill Supreme Court vacancy MORE (R-Utah) had pithier advice for Trump.

“I wish he would just stay out of it,” he told reporters.

The Memo is a reported column by Niall Stanage, primarily focused on Donald Trump’s presidency.