Bill O'Reilly is no stranger to having controversial figures on his show. Usually, O'Reilly interrupts his guest whenever the guest starts to make a valid point, but not here. In 2001, O'Reilly conducted an interview with Marilyn Manson as part of the show's Children at Risk segment.

Marilyn Manson conducts himself in a professional manner and fields questions from O'Reilly in regards to the use of profanity, religion, sex and Manson's appearance. The rocker continuously keeps his poise, offers intellectual responses and even manages to get in a dig at the media when the Columbine shooting is brought up.