The RPSCA has laid a record number of charges to the owner of an alleged puppy farm in southern Queensland where dogs were kept in "appalling conditions".

In January, 81 malnourished dogs and 10 cats were seized by police and RSPCA officials from the property at Glenarbon.

RSPCA inspector Daniel Young said the owner, Haris Ljuhar, 40, had been charged with 215 animal welfare-related offences.

More than 80 dogs were seized from the alleged puppy farm in January. ( Supplied: RSPCA )

"There was inadequate shelter and water and a number of the dogs were carrying injuries that needed urgent veterinary treatment," Mr Young said.

"There was one dog that was sharing a small space with a dog that was deceased and there were the remains of a number of corpses lying near dogs that were tethered."

Most of the dogs were American Staffordshire bull terriers, as well as Australian, American and French bulldogs.

It was the most charges the RSPCA has ever issued for the one person.

Mr Young said the operation including veterinary fees for the animals and the cost of care and rehoming had cost the RSPCA more than $100,000.

Mr Ljuhar is due to appear in Goondiwindi Magistrates Court in May.