WASHINGTON  House Republicans on Friday rolled out what they called historic cuts in federal spending after conservatives in the party’s new majority demanded that the leadership follow through on a pledge to carve $100 billion from the current year’s budget.

The spending bill, put forward by the Appropriations Committee for consideration on the floor next week, proposes slashing a wide portfolio of domestic programs and foreign aid. It blocks the spending of about $2 billion in unused economic stimulus money and seeks to prevent the Internal Revenue Service from enforcing the new health care law. The measure also cuts financing directly from the office of the president.

Republicans take aim at some of their favorite targets in the measure, reducing financing to the Environmental Protection Agency by $3 billion  an almost 30 percent cut from current levels. The measure would also block the agency from implementing new emissions regulations, and it would cut more than $100 million in spending on climate change programs.

Housing, energy and transportation spending is also trimmed substantially. Dozens of programs, including the Corporation for Public Broadcasting, are eliminated.