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WASHINGTON — Donald Trump's Inauguration Day festivities triggered a wave of turbulent demonstrations, dissent and dozens of arrests Friday as protesters brought traffic to a crawl in the nation's capital.

After a night of chaotic clashes between police and protesters, violence erupted again in the city's downtown, about five blocks from the presidential parade route.

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Dozens of protesters — some self-described "anarchists" dressed in black and wearing masks — damaged businesses at 10:30 a.m. ET just before Trump's swearing-in ceremony got underway, Metropolitan police said.

Authorities arrested 95 people — some charged with rioting — in the Franklin Park area and acting Police Chief Peter Newsham said there was "significant damage" to at least four businesses. Two police officers suffered minor injuries as protesters flung bricks, trash cans and other objects, and ignited small fires.

Police use pepper spray on protesters in Washington, Jan. 20, 2017, in a chaotic confrontation blocks from Donald Trump's inauguration as protesters registered their rage against the new president. Mark Tenally / AP

"I saw one guy, he was like pushing a cop, kind of antagonizing him, and the cop with the riot shield was banging him back," Johnny Silvercloud, a freelance journalist who was photographing protesters, told NBC News.

One man was accidentally knocked over by protesters, a law enforcement officer told NBC News. He was bleeding from the back of his skull as paramedics helped him onto a stretcher.

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Related: D.C. Braces for Tens of Thousands of Protesters During Trump’s Inauguration Week

Despite the arrests, the demonstrations continued through the afternoon, and police used pepper spray and flash-bang grenades to hold back the crowds, refusing to let people closer to the parade route.

Police arrest and detain a protester in the street in Washington, D.C. Protesters took to the streets to march against presidential inauguration of Donald Trump. Stefan Jeremiah / Rex Features via AP

What is largely a day of jubilation for the new president has been defined by mass protests that are expected to strengthen through the weekend. A Women’s March on Washington set for Saturday is expected to draw 200,000 protesters — a number that Inaugural Historian Jim Bendat said could break records.

Meanwhile, Interstate 695, which runs through the capital, came to a standstill Friday afternoon as people holding signs and waving flags stopped traffic.

D.C. Mayor Muriel Bowser has said more than 3,000 police officers from other regions and 5,000 National Guardsmen are on hand to help secure the parade route.

With hundreds of thousands descending on D.C., security checkpoints were choked with foot traffic earlier Friday as inauguration ceremony ticket-holders weaved through demonstrators to get to Capitol Hill.

The protesters chanted and carried signs — many attacking Trump or making other political and social statements, including "Not my president," "No Islamophobia" and "Black Lives Matter."

Demonstrators protest against President Donald Trump in Washington, D.C., on Jan. 20, 2107. Jewel Samad / AFP - Getty Images

Protesters Joni Lipson and Joan Duckenfield, both of Philadelphia, said they were buoyed by the huge turnout of protesters.

"It looks like there are more of us than Trump supporters here," Duckenfield said.

Trump supporters at one checkpoint at 10th and E streets tried to thread their way past a group of self-described "anarchists." But the demonstrators locked arms and inadvertently tripped a pro-Trump couple trying to pass.

Police immediately pounced and untangled everybody, while the protesters roared "Don't touch me" and "Stop! Stop!" Nobody was arrested.

A protester has her eyes doused with water after being pepper sprayed by police outside of the DeploraBall at the National Press Building in Washington on Jan. 19. Patrick Smith / Getty Images

The scene was just one tense moment that played out after police deployed pepper spray as hundreds rallied Friday night outside the National Press Club, where a pro-Trump event billed as the "DeploraBall" was being held. Some demonstrators set off smoke devices in the middle of the crowd, and police in riot gear mobilized to block entrance to the event.

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"Impeach the predatory president," read one of two messages projected onto the building’s façade. Crowds chanted "Nazi scum" at those who entered. Some of the protesters were with the group Refuse Fascism.

Firecrackers went off, protesters seem to have chased DeploraBall attendees. Pepper spray used and riot police arrived #Inauguration — Phil McCausland (@PhilMcCausland) January 20, 2017

But the protests have also included rallies for causes other than directly opposing Trump.

A group against the Dakota Access Pipeline, for example, confronted police Friday morning at the 14th and F streets entrance into the parade route. Police pulled protesters away from the checkpoint, amid cries of "No warning!"

Water protectors - Dakota Access Pipeline protesters - clash with cops at entry to parade route @ 14th & F pic.twitter.com/sVaLpyxIJ9 — Alexandra Jaffe (@ajjaffe) January 20, 2017

Others, like the pro-marijuana legalization group DCMJ advocated on their own behalf. Marijuana use is legal in Washington, and DCMJ handed out thousands of marijuana cigarettes, or joints, for free to show support for legalization.

More than 10,000 people had gathered Friday morning in DuPont Circle, in a line stretching five blocks long, to pick up their weed, said DCMJ co-founder Nikolas Schiller. They planned to march toward the National Mall and light up at exactly 4 minutes and 20 seconds into Trump's inaugural address — a nod to the number "420" which is code for marijuana/getting high.

"I got my joint and it's wonderful," Justice Shakur, who drove from Baltimore, told NBC News, adding that "you can be a Trump supporter and still like marijuana."

Folks have been waiting in line for @DCMJ2014 weed giveaway since 5 a.m. Organizers are handing out donuts #Inauguration pic.twitter.com/EZOifHdJWN — Phil McCausland (@PhilMcCausland) January 20, 2017

The demonstrations in D.C. have been one of several held throughout the country in opposition to Trump, including a "unity" demonstration outside Trump International Hotel in New York. The event got a boost of star power from Robert De Niro, Sally Field and Mark Ruffalo.