Over 10 days, they will drive across 1,600 grueling, off-road miles in the Nevada and California deserts, where the afternoons can reach 100 degrees and the nights can dip to 15. On their hunt for just under 200 hidden checkpoints, they will rely on map and compass skills, as well as driving prowess, physical stamina and more.

They are the roughly 100 women who will compete in the annual Rebelle Rally starting next week, armed with analog navigation tools: a map, a compass and a road book, but no cellphones or GPS devices.

Last year, Emily Benzie and her mother made up the Jeep Thrills team. “It was an amazing experience that tested my skills under sleep deprivation and long, dusty hours,” Ms. Benzie said. “Imagine summer camp for off-roading die-hards, where every day you drive an insane obstacle course and every night you camp around a fire hearing stories from the most hard-core women you envision — that’s Rebelle.”

Ms. Benzie, a genetic immunologist in San Francisco, drove, and her mother, Christine Benzie, navigated.