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"I think there's something about them where fans sometimes feel like that might be inevitable, so they're getting ahead of it. So I don't think it surprises me because I think it's a logical place to go," Beers told us. "Look, they're best friends, so I think emotionally—and I've always been a giant Alex fan, like from the beginning. I was like, 'People are way, way underestimating the power of Alex.' They were like, 'Oh, he's mean and he's a bad boy,' but in season two, when you realize he has a thing for Izzie and he gives her a cupcake and she's all Denny Duquette about stuff, and there's this one scene where you see that he's going to give her the cupcake and he sees her with Denny and this thing happens, and I became very righteous on Alex's behalf. So any given chance, I was about Alex. He's deep."

Her own superfan feelings for Karev aside, Beers admitted that the desire to see Mer and Alex together makes sense, though it's far from the only options people are rooting for out there in the Grey's fandom. "From my perspective, I understand the reaction because I think you also just love these two people and you want them both to be happy, and that's a natural thing too," she said. "But then there's so many Alex-Jo fans—like, the Alex-Jo fans are crazyballs! So it's nice—there's a little bit of something for everybody right now."