A woman in her 40s has died after a hit-and-run collision in the Briar Hill area Monday afternoon, police said.

Police were called to the area of Dufferin St. and Briar Hill Ave. around 3 p.m. Monday for reports of a pedestrian hit by a vehicle. An emergency run was called when the injuries — initially judged as serious — turned out to be life-threatening, police said.

Toronto Police Const. David Hopkinson confirmed the woman succumbed to her injuries in hospital.

Police said the driver fled the scene and is described as a white man in his 30s who was wearing a construction vest at the time of the incident. According to witnesses the vehicle is a silver Ford F150, police said.

Anyone who believes they have information is encouraged to speak to police.

Dufferin St. continues to be closed in both directions from Briar Hill Ave. to Wingold Ave. Police said closures will likely remain in effect for an extended period of time. Traffic services is now investigating.

Another pedestrian was hit Monday afternoon in the area of McRoberts and Innes Aves, paramedics said. Toronto paramedics said they responded to the call just after 3:30 p.m. Monday.

They said a female pedestrian in her 80s had been hit by a vehicle. Paramedics transported her to hospital in serious condition.