We thank M. L. Mather, E. Maratos-Flier, R. Garrity, Z. Deng, A. Mina and D. Cabarkapa for help with CLAMS studies. We thank T. Jacks for his support and input for this project as C.J.’s postdoctoral advisor. We thank S. L. Gaffen and Y. Iwakura for sharing the Il17f −/− mice, J. K. Kolls for the Il17rc fl/fl mice, and Amgen for the Il17rc −/− and Il17ra −/− mice. We thank A. Mann, N. Asinovski and K. Hattori for the Vγ6Vδ1 transgenic mice and the 17D1 antibody. We thank C. Zhao for help with the immunofluorescence staining and confocal imaging analysis; L. Kazak and E. T. Chounchani for help with the EMG study; and R. J. Akhurst and S. Basu for sharing mice. We thank the Nikon Imaging Center at Harvard Medical School for all imaging studies; the Rodent Histology Core at Harvard Medical School for histology studies; the viral core at Children’s Hospital Boston for AAV production; and the Neurobiology Department and the Neurobiology Imaging Facility for consultation and instrument availability that supported this work. This facility is supported in part by the Neural Imaging Center as part of an NINDS P30 Core Center grant NS072030. We thank Z. Herbert, A. Caruso and members of the Molecular Biology Core Facilities at the Dana-Farber Cancer Institute for RNA-seq analysis. We thank the Flow Cytometry Core Facilities at the Swanson Biotechnology Center at MIT and the Dana-Farber Cancer Institute. We thank Y. Chen, D. Bogoslavsk, J. Szpyt and all members of the Spiegelman and Mathis laboratories for help and input in this project. B.H. is a Cancer Research Institute/Leonard Kahn Foundation Fellow. C.J. is supported by a K99 Award (CA226400) from the National Cancer Institute (NCI). This work was supported by grants to B.M.S. from the NIH DK 31405 and from the JPB Foundation.