Budget Director Mick Mulvaney will this week inform federal agencies to plan on major cuts, Axios reports.

President Donald Trump in mid-March unveiled his first budget blueprint, proposing $54 billion in cuts that would slash many domestic programs, such as the Environmental Protection Agency, foreign aid, medical research, help for homeless veterans and community development grants to finance a significant increase in the military and make a down payment on the U.S.-Mexico border wall.

"A budget that puts America first must make the safety of our people its number one priority — because without safety, there can be no prosperity," Trump said in a message accompanying his proposed budget that was titled "America First: A Budget Blueprint to Make America Great Again."

"This is a hard power budget, not a soft power budget," Mulvaney said then.

In the mid-March budget, the FBI was to be spared while the border wall would receive an immediate $1.4 billion infusion in the ongoing fiscal year, with another $2.6 billion planned for the 2018 budget year starting Oct. 1.

Mulvaney's office will send a "guidance" letter to federal agencies this week expanding on Trump’s March 13 executive order calling for a "comprehensive plan" to "improve the efficiency, effectiveness, and accountability of the executive branch."