Dozens of people have been killed and more than 180 people — including children — have been injured after a suicide bomber targeted a large wedding in Afghanistan's capital Kabul on Saturday.

Key points: Afghan officials said 63 people were killed and another 182 were wounded, including children

Afghan officials said 63 people were killed and another 182 were wounded, including children Earlier this month, a car bomb killed 14 people and wounded 145 on the same road

Earlier this month, a car bomb killed 14 people and wounded 145 on the same road The US is currently in negotiations for its troops to leave the country

Interior Ministry spokesman Nusrat Rahimi said the attacker set off explosives among the wedding celebrations.

One witness said there may have been as many as 1,000 people in attendance.

Afghan officials confirmed that 63 people were killed and another 182 were wounded in the blast.

Both the Taliban and a local affiliate of the Islamic State group carry out bloody attacks in the capital, however the Taliban denied responsibility.

But Afghan president Ashraf Ghani said that the Taliban could not escape blame for the "barbaric" attack, adding that the extremist group had provided a "platform for terrorists".

Afghan journalist Sana Safi, who works for the BBC, said she doubted the Taliban's denial.

"Who else is capable of carrying out such brutality?" she said.

The blast occurred near the stage at the Dubai City wedding hall in western Kabul, a part of the city that many in the minority Shiite Hazara community call home.

This Afghan man's brother was killed in the explosion at the Dubai City wedding hall. ( AP: Rafiq Maqbool )

Witness Gul Mohammad said musicians were playing on the stage, which was surrounded by "all the youths, children and all the people who were there were killed".

One of the wounded, Mohammad Toofan, said that "a lot of guests were martyred".

"There are so many dead and wounded victims," said Ahmad Omid, who survived the blast.

"I was with the groom in the other room when we heard the blast and then I couldn't find anyone. Everyone was lying all around the hall."

A local hospital was inundated with those who were wounded and their families.

A wounded man is taken to hospital after the explosion. ( AP: Nishanuddin Khan )

The attack came as the Taliban and the United States tried to negotiate an agreement on the withdrawal of US forces from Afghanistan in exchange for a Taliban commitment on security and peace talks with the US-backed government.

Sediq Seddiqi, spokesman for President Ashraf Ghani, said his government was waiting to hear results of President Donald Trump's meeting on Friday with his national security team about the negotiations.

Mr Seddiqi posted on Twitter that he was "devastated" by the attack.

"A heinous crime against our people; how is it possible to train a human and ask him to go and blow himself (up) inside a wedding?!!"

Following the blast,

On August 7, a Taliban car bomb aimed at Afghan security forces detonated on the same road, killing 14 people and wounding 145; most of them women, children and other civilians.

AP/Reuters