By PTI

WASHINGTON: Traffic-related pollution caused asthma among 350,000 children in India in 2015, second only to China, according to a study that analysed 194 countries and 125 major cities worldwide, reports Lancet.

The first global estimates of their kind published in The Lancet Planetary Health journal suggest that more than one in ten childhood asthma cases could be linked to traffic-related air pollution every year.

With 92 per cent of cases developing in areas that have traffic pollution levels below the World Health Organization (WHO) guideline level, the researcher suggest that this limit may need to be reviewed.

"Nitrogen dioxide pollution appears to be a substantial risk factor for childhood asthma incidence in both developed and developing countries, especially in urban areas," said Susan Anenberg from George Washington University, US.

"Our findings suggest that the World Health Organization guideline for annual average NO2 concentrations might need to be revisited, and that traffic emissions should be a target to mitigate exposure," Anenberg said in a statement.

"Our study indicates that policy initiatives to alleviate traffic-related air pollution can lead to improvements in children's health and also reduce greenhouse gas emissions," said lead author Ploy Achakulwisut from George Washington University.

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Traffic-related air pollution may result in asthma development as pollutants may cause damage to the airways, leading to inflammation that triggers asthma in genetically predisposed children.

The researchers used NO2 as a surrogate for the traffic pollution mixture to focus specifically on the effects of traffic pollution on childhood asthma development.

NO2 is a pollutant formed mainly from fossil fuel combustion, and traffic emissions can contribute up to 80 per cent of ambient NO2 in cities.

NO2 is just one component of air pollution, which is made up of many pollutants (including particulate matter, ozone, carbon monoxide), which are known to have numerous adverse effects on health.

The researchers combined a global dataset of ambient NO2 -- modelled from ground-level monitors, satellite data, and land use variables such as road networks -- with data on population distribution and asthma incidence to estimate the number of new traffic pollution-related asthma cases in children aged 1-18 years.

Globally, the estimates suggest that there are 170 new cases of traffic pollution-related asthma per 100,000 children every year, and 13 per cent of childhood asthma cases diagnosed each year are linked to traffic pollution.

The country with the highest rate of traffic pollution-related childhood asthma was Kuwait (550 cases per 100,000 children each year), followed by the UAE (460 per 100,000), and Canada (450 per 100,000).

The largest number of cases of traffic pollution-related asthma were estimated for China (760,000 cases), which is likely a result of China having the second largest population of children and the third highest concentrations of NO2, researchers said.

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Although less than half the size of China's burden, India had the next largest number of cases (350,000) due to its large population of children, they said.

The US (240,000), Indonesia (160,000) and Brazil (140,000) had the next largest burdens, with the US having the highest pollution levels of these three countries, while Indonesia had the highest underlying asthma rates.

The country with the highest percentage of traffic pollution-attributable childhood asthma incidence was South Korea (31 per cent), followed Kuwait (30 per cent), Qatar (30 per cent), UAE (30 per cent), and Bahrain (26 per cent).

The UK ranked 24th out of 194 countries, the US 25th, China 19th, and India 58th, researchers said.

They explain that India ranks below other countries for this metric because, although levels of other pollutants -- particularly PM2.5 -- in India are among the highest in the world, NO2 levels from 2010-2012 in Indian cities appear to be lower than or comparable to levels in European and US cities.

Two-thirds of traffic pollution-related asthma cases occurred in urban centres globally, and when suburbs were included this proportion increased to 90 per cent of cases.

Of the ten cities with the highest proportion of traffic pollution-related asthma cases, eight were in China alongside Moscow, Russia, and Seoul, South Korea -- all of which had high urban NO2 concentrations.

Paris ranked 21st (33 per cent), New York ranked 29th (32 per cent), London 35th (29 per cent), and New Delhi 38th (28 per cent).

The researchers note some limitations, including that studies linking traffic pollution and asthma, and NO2 monitoring data are largely from North America, Europe and east Asia, and NO2 ground-level monitors are mostly in urban areas, so could overestimate pollution levels in rural areas.

Due to limited data availability, the NO2 levels used in this study are for 2010-2012, whereas the population and asthma incidence rates are for 2015.