Some of the boxes stacked inside anthropologist Molly Zuckerman's laboratory contain full bones -- a skull, a jaw, or a leg. Others contain only plastic bags of bone fragments that Zuckerman describes as "grit."

These humble remains are among as many as 7,000 bodies that were buried at Mississippi's former insane asylum, a site that's now on the grounds of the University of Mississippi Medical Center in Jackson. Researchers are planning to exhume the bodies, create a memorial and study them for insight on how the mentally ill and other marginalized populations should be treated today.

"The individuals present this amazing snapshot of life and health and human biology in Mississippi during a really tumultuous time spanning from before the Civil War into Reconstruction and into Jim Crow," said Zuckerman, who operates her lab at Mississippi State University in Starkville. "This can provide a very rich, contextualized, detailed and personal understanding of how health changed throughout time and how people's health was influenced by structural factors such as poverty and racism and marginalization."

The Mississippi State Lunatic Asylum -- later renamed the Mississippi State Insane Hospital -- operated from 1855 to 1935 and housed up to 35,000 patients from across the state. Patients who died while institutionalized were buried there if relatives didn't claim their bodies.

While researchers have limited information on those buried at the site, Zuckerman said many suffered from syphilis and associated mental symptoms at a time before antibiotics were known as an effective cure. Others' conditions ranged from schizophrenia to postpartum depression in an era when mental health wasn't well understood. Racial and economic backgrounds appear to have varied.

Pockets of remains had been found on the university's campus since the 1990s. But during a 2012 survey for planned road construction, archaeologists made the startling discovery that there are at least 3,000 buried bodies -- and possibly as many as 7,000.

A group of seven universities in Mississippi and Texas has created a consortium to memorialize and analyze the remains.

7,000 bodies may be buried at the site of Mississippi's former insane asylum. Researchers plan to study them for insights on how mentally ill people should be treated. https://t.co/y4xCARoa3H pic.twitter.com/qnXGTTj8Uq — AP South U.S. Region (@APSouthRegion) May 23, 2018

Ralph Didlake, the director of UMMC's Center for Bioethics and Medical Humanities, said the consortium aims "to respectfully manage the remains in a way that leverages their cultural value, honors their legacy and history and scientific value." Didlake hopes to receive about $2 million from Mississippi legislators for the project, after which he believes private donations will sustain it.

So far the exhumed remains of 66 people are housed at Zuckerman's lab. Zuckerman said the patients were laid to rest with respect in individual coffins. Their unmarked graves and lack of personal effects were common burial practices for the time, she said.

In one box is a nearly full human skull from a young female patient, said Assistant Professor Anna Osterholtz, pointing to three dents in the skull that came from traumatic impacts. One is so severe that Osterholtz said the blow could have caused permanent brain damage. It's not clear whether the blow came before or after the patient was institutionalized.

One of Zuckerman's graduate students inspected cross-sections of bones to find evidence of pellagra, or vitamin B deficiency, in the patients. Likely a result of a diet of corn, fatback and molasses, the condition can cause dementia-like symptoms.

Skeletal remains can also show evidence of chronic disease. Syphilis in its late stages, for instance, can cause small brain tumors that result in moth hole-like craters in the skull.

From teeth, anthropologists can gather information on people's diets and even discern what county they're from.

Identifying the patients, though, is difficult. The coffins are not marked. Anthropologists have recovered patient records, but there is no map to match records to gravesites. DNA analysis is costly, and DNA strands can degrade beyond recognition after decades underground.

Karen Clark, who has studied state records and her family's genealogy, said her great-great-great-grandfather Isham Earnest is buried at the site. She has no problem with the university digging up the graves, and she hopes DNA testing could point her to her ancestor's remains.

"Why not use the latest technology if it exists?" she asked.

Zuckerman said studying how the mentally ill were treated in the asylum's era will help researchers understand how to improve treatment for marginalized populations of today, whether they're affected by mental illness, racism, sexism or poverty.

"The only way you can really justify doing work on human remains -- because of how ethically loaded the question of human remains is -- is if you generate information from them that is useful and beneficial to modern and future populations," Zuckerman said.