A major south Brisbane road will be partially closed for three months so a $28 million upgrade can be completed.

Green Camp Road between Manly and Rickertt roads at Wakerley and Ransome is used by 30,000 vehicles a day and has been identified as a priority project by the Brisbane City Council as it wants to reduce congestion, improve safety and traffic efficiency.

Design image of the $28 million Green Camp Road upgrade at the intersection of Tilley Road. Credit:Brisbane City Council

More than 5000 of those motorists will be affected when 200 meters of Tilley Road is closed while the road works is undertaken.

There have been 57 crashes along the stretch of road in the past seven years, with 46 requiring medical treatment of hospitalisation.