It was a speech that inspired the fantasies of Democrats across America, all of them centered on a single question: Will Oprah Winfrey run for president in 2020?

Now, less than two weeks after those hopes were raised, an interview has appeared to dash those hopes — or at least muddy the waters.

In an interview for the March issue of InStyle, the beauty and fashion magazine, the former talk show host was asked how she felt about the prospect of what would have been a historic campaign to put a black woman in the White House. The interview was conducted three weeks before her speech at the Golden Globes, InStyle confirmed Thursday.

“I’ve always felt very secure and confident with myself in knowing what I could do and what I could not,” she said. “And so it’s not something that interests me. I don’t have the DNA for it.”