Barnard E.A.

et al. International Union of Pharmacology. XV. Subtypes of gamma-aminobutyric acidA receptors: classification on the basis of subunit structure and receptor function. Pharmacol. Rev. 50 : 291-313 View in Article PubMed

Google Scholar

Steiger J.L.

et al. cAMP response element-binding protein, activating transcription factor-4, and upstream stimulatory factor differentially control hippocampal GABABR1a and GABABR1b subunit gene expression through alternative promoters. J. Neurosci. 24 : 6115-6126 View in Article Scopus (77)

PubMed

Crossref

Google Scholar

Urwyler S.

et al. Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501. Mol. Pharmacol. 60 : 963-971 View in Article PubMed

Google Scholar

Cryan J.F.

et al. Behavioural characterization of the novel GABA B receptor positive modulator GS39783 (N, N′- dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-Diamine): Anxiolytic-like activity without side-effects associated with baclofen or benzodiazepines. J. Pharmacol. Exp. Ther. 310 : 952-963 View in Article Scopus (176)

PubMed

Crossref

Google Scholar

Holmes, A. and Cryan, J.F. Modelling human anxiety and depression in mutant mice. In Transgenic and Knockout Models of Neuropsychiatric Disorders (Fisch, G. and Flint, J., eds) Humana Press (in press) View in Article Google Scholar

Association A.P. Diagnostic and Statistical Manual of Mental Disorders. 4th edn. American Psychiatric Press , View in Article Google Scholar

Cannistraro P.A.

Rauch S.L. Neural circuitry of anxiety: evidence from structural and functional neuroimaging studies. Psychopharmacol. Bull. 37 : 8-25 View in Article PubMed

Google Scholar

Nastiti K.

et al. The effects of compounds acting at the benzodiazepine receptor complex on the ultrasonic calling of mouse pups. Behav. Pharmacol. 2 : 121-128 View in Article PubMed

Google Scholar

Quintero S.

et al. The effects of compounds related to gamma-aminobutyrate and benzodiazepine receptors on behavioural responses to anxiogenic stimuli in the rat: punished barpressing. Psychopharmacology (Berl.). 85 : 244-251 View in Article Scopus (45)

PubMed

Crossref

Google Scholar

Andrews N.

File S.E. Increased 5-HT release mediates the anxiogenic response during benzodiazepine withdrawal: a review of supporting neurochemical and behavioural evidence. Psychopharmacology (Berl.). 112 : 21-25 View in Article Scopus (65)

PubMed

Crossref

Google Scholar

Addolorato G.

et al. Pharmacological approaches to the management of alcohol addiction. Eur. Rev. Med. Pharmacol. Sci. 6 : 89-97 View in Article PubMed

Google Scholar

Nakagawa Y.

et al. Involvement of GABA(B) receptor systems in action of antidepressants: baclofen but not bicuculline attenuates the effects of antidepressants on the forced swim test in rats. Brain Res. 709 : 215-220 View in Article Scopus (49)

PubMed

Crossref

Google Scholar

Nakagawa Y.

et al. Involvement of GABAB receptor systems in action of antidepressants. II: Baclofen attenuates the effect of desipramine whereas muscimol has no effect in learned helplessness paradigm in rats. Brain Res. 728 : 225-230 View in Article Scopus (34)

PubMed

Crossref

Google Scholar

Nakagawa Y.

et al. Involvement of GABAB receptor systems in experimental depression: baclofen but not bicuculline exacerbates helplessness in rats. Brain Res. 741 : 240-245 View in Article Scopus (42)

PubMed

Crossref

Google Scholar

Heese K.

et al. GABA(B) receptor antagonists elevate both mRNA and protein levels of the neurotrophins nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) but not neurotrophin-3 (NT-3) in brain and spinal cord of rats. Neuropharmacology. 39 : 449-462 View in Article Scopus (73)

PubMed

Crossref

Google Scholar

Shirayama Y.

et al. Brain-derived neurotrophic factor produces antidepressant effects in behavioral models of depression. J. Neurosci. 22 : 3251-3261 View in Article PubMed

Google Scholar

Slattery D.A.

et al. GABA B receptor antagonist-mediated antidepressant-like effects are serotonin dependent. J. Pharmacol. Exp. Ther. 312 : 289-295 View in Article Google Scholar

Kniazeff J.

et al. No ligand binding in the GB2 subunit of the GABA(B) receptor is required for activation and allosteric interaction between the subunits. J. Neurosci. 22 : 7352-7361 View in Article PubMed

Google Scholar

Kulik A.

et al. Subcellular localization of metabotropic GABA(B) receptor subunits GABA(B1a/b) and GABA(B2) in the rat hippocampus. J. Neurosci. 23 : 11026-11035 View in Article PubMed

Google Scholar

Cryan, J.F. et al. The tail suspension test as a model for assessing antidepressant activity: review of pharmacological and genetic studies in mice. Neurosci. Biobehav. Rev. (in press) View in Article Google Scholar

Nakagawa Y.

Takashima T. The GABA(B) receptor antagonist CGP36742 attenuates the baclofen- and scopolamine-induced deficit in Morris water maze task in rats. Brain Res. 766 : 101-106 View in Article Scopus (58)

PubMed

Crossref

Google Scholar