A teenager has been stabbed during an early morning attack at an apartment in Melbourne's CBD.

The 18-year-old was set upon my two men at 7.30am on Sunday at a Little Bourke Street apartment before the attackers fled the scene. They remain on the run.

He was treated by paramedics at the scene who were forced to cut off his trousers to access a wound on his leg.

View photos The teen suffered several stab wounds during an altercation in Melbourne's CBD. Source: 7 News More

His head was also bandaged following a slash wound before he was taken to a nearby hospital.

His friends tried to fight off the attackers and they too were injured in the altercation.

"Look at my finger cuz, these n****** stabbed my finger for no reason," friend Adnandez Abdir said.

View photos His trousers were cut to access a stab wound to the leg. Source: 7 News More

"For no reason, look at my forehead as well for no reason bro."

Police were quick to swoop on a man who was initially thought to be involved but was later released.

"There was about like five of them cuz, three of them had a knife cuz, three or four asian kids wearing all black," Abdir added.

View photos Friend Adnandez Abdir was also set upon as he tried to break up the altercation. Source: 7 News More

The three attackers are still on the run and are believed to be known to the victims.

A police statement says the stabbing occurred inside the property's apartment block but witnesses have said the violence spilled out onto the street.

"We were just waking to get into another club cuz and we got jumped straight away cuz, no warning no nothing cuz," Abdir said.

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