“Saturday Night Live” will turn to a familiar face to open its 39th season on NBC: Tina Fey, who will be the guest host for the premiere on Sept. 28.

On Monday, NBC announced the “SNL” guest lineup for the first three new shows of the fall season, leading off with Ms. Fey, one of the biggest stars the show has produced.

And the booking for the second week is sure to raise a few eyebrows — and some ratings points: Miley Cyrus, fresh from her much-commented on turn at the MTV Video Music Awards, will double as the guest host and musical guest on Oct. 5.

A third big name, Bruce Willis, will appear on Oct. 12, his second appearance as host.

The music acts are also high-profile. Arcade Fire will appear with Ms. Fey in the opener, and Katy Perry is booked on the show with Mr. Willis.