Nike Inc. is planning to air a new “Just Do It” TV commercial during the opening game of the NFL’s new season Thursday that will be narrated by Colin Kaepernick and feature a number of other athletes, including Odell Beckham Jr., LeBron James and Serena Williams.

The ad urges people to follow their dreams and ignore those who say it can’t be done. “Calling a dream crazy is not an insult,” Kaepernick says in the new Nike spot. “It’s a compliment.”