* Measles is infecting millions, all regions affected - WHO

* Highly contagious virus killed 140,000 in 2018, mostly children

* WHO says rates of vaccination are stagnating worldwide

* Mistrust of authorities and misinformation partly to blame (Adds comment, reaction)

By Kate Kelland, Health and Science Correspondent

LONDON, Dec 5 (Reuters) - Measles infected nearly 10 million people in 2018 and killed 140,000, mostly children, as devastating outbreaks of the viral disease hit every region of the world, the World Health Organization said on Thursday.

In figures described by its director general as "an outrage", the WHO said most of last year's measles deaths were in children under five years old who had not been vaccinated.

"The fact that any child dies from a vaccine-preventable disease like measles is frankly an outrage and a collective failure to protect the world's most vulnerable children," said the WHO's director general Tedros Adhanom Ghebreysus.

The picture for 2019 is even worse, the WHO said, with provisional data up to November showing a three-fold increase in case numbers compared with the same period in 2018.

The United States has already reported its highest number of measles cases in 25 years in 2019, while four countries in Europe - Albania, the Czech Republic, Greece and Britain – lost their WHO "measles-free" status in 2018 after suffering large outbreaks.

An outbreak in the South Pacific nation of Samoa has infected more than 4,200 people and killed more than 60, mostly babies and children, in a battle complicated by a vocal anti-vaccination movement.

In 2018, measles hit hardest in Liberia, Ukraine, Democratic Republic of Congo, Madagascar and Somalia, the WHO said, with these five nations accounting for nearly half of all cases worldwide.

Globally, measles vaccination rates have stagnated for almost a decade. The WHO and the UNICEF children's fund say that in 2018, around 86% of children got a first dose of measles vaccine through routine vaccination plans, and fewer than 70% got the second dose recommended to fully protect them.

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STAGGERING

Heidi Larson, director of the Vaccine Confidence Project at Britain's London School of Hygiene & Tropical Medicine, said the numbers were "staggering".

"Some countries are scrambling to vaccinate in the face of serious outbreaks - far too late for many," she said.

Measles is one of the most contagious known diseases, more so than Ebola, tuberculosis or flu. It can linger in the air or on surfaces for several hours after an infected person has been and gone, putting anyone not vaccinated at risk.

Among wealthier nations, vaccination rates have been hurt by some parents shunning them for what they say are religious or philosophical reasons. Mistrust of authority and debunked myths about links to autism also weaken vaccine confidence and lead some parents to delay protecting their children.

Research published in October showed that measles infection not only carries a risk of death or severe complications including pneumonia, brain damage, blindness and deafness, but can also damage the victim's immune memory for months or years - leaving those who survive measles vulnerable to other dangerous diseases such as flu or severe diarrhoea.

The WHO data showed there were an estimated 9,769,400 cases of measles and 142,300 related deaths globally in 2018. This compares to 7,585,900 cases and 124,000 deaths in 2017.

Charlie Weller, head of vaccines at the Wellcome Trust global health charity, said the numbers were a tragedy. "If we are to protect lives, we must understand and address the reasons why measles vaccine uptake is lower," she said.

(Reporting by Kate Kelland, editing by Gareth Jones and Hugh Lawson)