PHOTOS: Hollywood's Biggest Real Estate Deals of the Week: Will and Jada Pinkett Smith, Kate Middleton, Dennis Quaid, Terry Semel

The 2007 horror thriller starred Smith as the last surviving human in a New York cityscape overrun by monsters that survived the plague that killed most of humanity. Co-written by Mark Protosevich and directed by Francis Lawrence, it grossed $585 million worldwide. It is unclear how the storyline will be developed in the new project since Smith's character, Robert Neville, perished at the end of the first film.

The CAA-repped Amel has the action thriller The Expatriate in production, and his screenplay Grace of Monaco is in development.

Smith produced Fox's recent release This Means War, and he stars in the Sony sequel Men in Black III, which hits theaters in May.