A mother of two was hit and killed by a truck while cycling in Melbourne's inner-west on Friday night, prompting calls for better bike infrastructure.

Arzu Baglar, 36, was cycling home to Moonee Ponds after visiting a friend when she was fatally struck in Yarraville about 6pm.

Greents Senator Janet Rice. Credit:Paul Jeffers

Ms Baglar is survived by her husband and their two young daughters, aged six and two.

Greens senator Janet Rice, a long-time bike advocate who helped establish the annual Ride to Work day, wants the Turnbull government to step in and address funding shortfalls around the country to reduce the number of cyclist deaths and injuries.