CNN commentator April Ryan is under fire after she said Melania Trump was not 'culturally American' while commenting on the First Lady's 'Be Best' campaign.

Ryan and CNN's Erin Burnett were discussing Melania's new anti-cyberbullying campaign when she made the controversial comment.

'This is a First Lady who is not culturally American, but she is learning the ways,' Ryan told Burnett.

'This is not just an American issue. These are not just American issues. These are international issues. Cyberbullying is an international issue.'

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CNN commentator April Ryan is under fire after she said Melania Trump was not 'culturally american' while discussing the First Lady's 'Be Best' campaign on Erin Burnett OutFront

Both Ryan and Burnett had pointed out the irony of Melania's campaign as Trump himself has become infamous for name-calling people on Twitter

Both Ryan and Burnett had pointed out the irony of Melania's campaign as Trump himself has become infamous for name-calling people on Twitter.

'She's well aware of her husband's cyberbullying,' Ryan said. 'He's considered by some, well many I would say, in different sectors, one of the biggest bullies.'

'He will call you out in a moment's notice and she stood in front of him and basically said she wants to show young people how it's done and do it right.'

A number of critics took to social media to blast Ryan for her comment about Melania, a Slovenia native who moved to the US in 1996 on a work visa.

Steven Cheung, the White House Director of Strategic Response, took aim at the CNN commentator on Twitter.

Trump signed a proclamation alongside Melania after she announced the 'Be Best' children's initiative in the Rose Garden of the White House in Washington, DC on Monday

A number of critics took to social media to blast Ryan for her comment about Melania, including Glenn Beck and White House Director of Strategic Response Steven Cheung

'On @OutFrontCNN, @AprilDRyan just said @FLOTUS is not "culturally American." What does that even mean?' he tweeted.

'On a day when Mrs Trump unveiled a very important initiative #BeBest, reporters can't bring themselves to talk about anything but rumors and innuendo.'

Glenn Beck also hit out at Ryan, tweeting: 'I know when some said that Obama wasn't fully "culturally American" reporters cried racism.'

'Now that you, a reporter, are saying the same, can they cry racism? Or do you just hate foreigners? Wow, this is easy, I see why the left likes it.'

Trump launched a years-long campaign to attempt to prove that Obama had not actually been born in America, even after the president released his birth certificate.

Melania launched her Be Best initiative on Monday, revealing it would aim to promote using social media positively, encourage healthy living, and combat opioid abuse.

'As we all know, social media can be both positively and negatively affect our children, but too often it is used in negative ways,' Melania said during a speech from the Rose Garden.

'When children learn positive online behaviors early on, social media can be used in productive ways and affect positive change.'

Melania launched her Be Best initiative on Monday, revealing it would aim to promote using social media positively, encourage healthy living, and combat opioid abuse

Melania went on to say that she believed children should be 'both seen and heard'.

'It is our responsibility as adults to educate and remind them that when they are using their voices - whether verbally or online - they must choose their words wisely and speak with respect and compassion.'

President Trump was sitting just feet away throughout the entire speech.

This isn't the first time Ryan has come under fire for comments regarding the Trump family.

Ryan said she was forced to contact the FBI for death threats she received after asking if Trump planned to resign over the Michael Cohen scandal.

Ryan had asked the question during a White House press briefing hours after Cohen's hotel room and offices were raided by FBI agents.

She was slapped down by Press Secretary Sarah Huckabee Sanders, who deemed the question 'ridiculous'.

'I've been getting death threats and we've been calling the FBI. This is real. I asked a simple question. I did not point a finger,' Ryan said on CNN.

'I asked a question and now my life is in jeopardy because of a question and I'm going to continue to do my job.'