Small businesses in Townsville have been faced with thousands of dollars in clean-up costs after a burst water main triggered serious flooding along a busy road.

Key points: A burst water main inundated a street in the Townsville suburb of Mysterton

A burst water main inundated a street in the Townsville suburb of Mysterton Businesses say it is another blow after last year's floods

Businesses say it is another blow after last year's floods The council says there will be a full investigation into what caused the pipe to burst

The pipe burst on Charters Towers Road at Mysterton in the early hours of Sunday morning and cut the road to traffic.

The Townsville City Council said crews worked "furiously" to drain mud and water from the area.

Archery supply shop owner Scott Murray said the flooding had devastated his business.

He spent the day sweeping mud from his store, which is expected to remain closed for several days.

"It's caused probably $90,000 to $100,000 worth of damage in lost stock," Mr Murray said.

Scott Murray spent the day sweeping mud out of his shop. ( ABC News: Lily Nothling )

He said counters, desks and computers had also been destroyed.

"It's been so hard for the last year and a half or so — to have this now just knocks you right down again," Mr Murray said.

"Even when Townsville had all the floods, we didn't get any water through the shop, but this makes up for it."

Councillor Mark Molachino, who chairs the council's infrastructure committee, said water and power had been switched off.

"It's quite an intricate web of water infrastructure underneath these roads and suburbs — it took a bit longer than expected," Cr Molachino said.

"Water mains burst, the ground shifts a lot of the time, but we'll have a full investigation into this to find out exactly the cause."

Hair salon owner Vikki Ratuere said the incident was another blow for her business, which was still recovering from the 2019 Townsville floods.

"We came down to investigate and found out the shop was totally underwater and flooded and muddy and horrible," Ms Ratuere said.

"Last year my shop flooded just up the road — we've been having renovations done to that at the moment, so we are temporarily moved here.

Vikki Ratuere's hair salon business is still recovering from floods in 2019. ( ABC News: Lily Nothling )

"Now we've been flooded again — not sure whether it follows me or I'm just unlucky. It's a bit sad."

Cr Molachino said the council would offer support for flood-affected businesses.

"We'll be working as closely as possible with those business owners to try and minimise the disruption as much as possible to try to get them back on their feet," he said.