A 47-year-old Cambridge man rushed to hospital with serious burns following an explosion in his Selkirk Street garage Wednesday has died from his injuries, confirm investigators with the Ontario fire marshal's office.

Fire investigator Ryan Lock was at the scene of the explosion Thursday, as crews began dismantling the detached garage to allow investigators to safely search for a cause of the explosion and resulting fire, which rocked the quiet west Galt neighbourhood just after 6 p.m.

"At this point in time, cause determination hasn't been made yet," said Lock. "Part of the issue is us being able to safely enter the garage due to the damage. The roof is compromised, so we can't safely go in with that risk."

So far, examination of the structure has only been around the exterior, he explained, but heavy equipment is now on-site to carefully remove the roof, allowing investigators to better search for clues.

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"We need to get inside to analyze everything."

Aside from the rumbling sounds of an excavator manoeuvring into the small home's driveway, Selkirk Street remained relatively quiet, a stark contrast from the previous evening. Neighbours described the chaotic scene for the Times.

"There was a huge blast, which shook my house at approximately 6:10 p.m.," said Joesph Boudrea in an email.

"At first, I thought my house was struck by something. I put my jacket and boots on and ran outside just in time to see flames begin to erupt from my neighbour's garage and to see my neighbour walk up his driveway to the front of his house. His clothing was covered in small pockets of flames."

He said a neighbour, who is a nurse, ran to his aid, directing him lie down in the snow to smother flames.

Within minutes, the detached garage was engulfed in flames and several smaller explosion bursts could be heard, he explained.