Last updated Dec 20, 2017

Most Recently Added

News/Commentary

New model for Zika virus can assist in testing vaccines and treatments (Coherent News, Dec 20)

As Zika babies become toddlers, some can’t see, walk or talk (New York Times, Dec 14)

U.S. study sheds light on how Zika causes nerve disorder (Reuters, Dec 13)

Could this zoo of mutant mosquitoes lead the way to eradicating Zika? (STAT, Dec 13)

Zika crisis (FullMeasure, Dec 10)

Responsible care in the face of shifting recommendations and imperfect diagnostics for Zika virus (Commentary in JAMA, Dec 5)

AAP releases new Red Book chapter on Zika (AAP News, Nov 30)

Selected Reading

Abbink P, Larocca RA, Visitsunthorn K, et al. Durability and correlates of vaccine protection against Zika virus in rhesus monkeys. Sci Transl Med 2017 (published online Dec 13)

Bautista LE. Maternal Zika virus infection and newborn microcephaly—an analysis of the epidemiological evidence. Ann Epidemiol 2017 (published online Dec 13)

Blackman MA, Kim IJ, Lin JS, et al. Challenges of vaccine development for Zika virus. Viral Immunol 2017 (published online Dec 11)

Carossino M, Li Y, Lee PYA, et al. Evaluation of a field-deployable reverse transcription-insulated isothermal PCR for rapid and sensitive on-site detection of Zika virus. BMC Infect Dis 2017 (published online Dec 19)

de Araujo TVB, de Alencar Ximenes RA, de Barros Miranda-Filho D, et al. Association between microcephaly, Zika virus infection, and other risk factors in Brazil: final report of a case-control study. Lancet Infect Dis 2017 (published online Dec 11)

Dirlikov E, Torres JV, Martines RB, et al. Postmortem findings in patient with Guillain-Barre syndrome and Zika virus infection. Emerg Infect Dis 2017 (published online Dec 19)

Dreier JW, Strandberg-Larsen K, Uldall PV, et al. Fever in pregnancy and offspring head circumference. Ann Epidemiol 2017 (published online Dec 6)

Dudley DM, Newman CM, Lalli J, et al. Infection via mosquito bite alters Zika virus tissue tropism and replication kinetics in rhesus macaques. Nat Commun 2017 (published online Dec 13)

Espinosa D, Mendy J, Manayani D, et al. Passive transfer of immune sera induced by a Zika virus-like particle vaccine protects AG129 mice against lethal Zika virus challenge. EBioMedicine 2017 (published online Dec 12)

Gaudinski MR, Houser KV, Morabito KM, et al. Safety, tolerability, and immunogenicity of two Zika virus DNA vaccine candidates in healthy adults: randomised, open-label, phase 1 clinical trials. Lancet 2017 (published online Dec 4)

Gloria-Soria A, Lima A, Lovin DD, et al. Origin of a high-latitude population of Aedes aegypti in Washington, DC. Am J Trop Med Hyg 2017 (published online Dec 18)

Gregory CJ, Oduyebo T, Brault AC, et al. Modes of transmission of Zika virus. J Infect Dis 2017 (published online Dec 16)

Hills SL, Fischer M, Petersen LR. Epidemiology of Zika virus infection. J Infect Dis 2017 (published online Dec 16)

Jia H, Zhang M, Chen M, et al. Zika virus infection in travelers returning from countries with local transmission, Guangdong, China, 2016. Travel Med Infect Dis 2017 (published online Nov 25)

J Infect Dis. Zika virus: a new threat emerges. (Special supplement) J Infect Dis 2017 Dec;216(suppl 10)

Kalkeri R, Murthy KK. Zika virus reservoirs: implications for transmission, future outbreaks, drug and vaccine development. F1000Res 2017 (published online Oct 17)

Kauffman EB, Kramer LD. Zika virus mosquito vectors: competence, biology, and vector control. J Infect Dis 2017 (published online Dec 16)

Leta S, Beyene TJ, De Clercq EM, et al. Global risk mapping for major diseases transmitted by Aedes aegypti and Aedes albopictus. Int J Infect Dis 2017 (published online Nov 28)

Lozier MJ, Burke RM, Lopez J, et al. Differences in prevalence of symptomatic Zika virus infection by age and sex — Puerto Rico, 2016. J Infect Dis 2017 (published online Dec 6)

Modjarrad K, Lin L, George SL, et al. Preliminary aggregate safety and immunogenicity results from three trials of a purified inactivated Zika virus vaccine candidate: phase 1, randomised, double-blind, placebo-controlled clinical trials. Lancet 2017 (published online Dec 4)

Morabito KM, Graham BS. Zika virus vaccine development. J Infect Dis 2017 (published online Dec 16)

Munoz-Jordan JL. Diagnosis of Zika virus infections: challenges and opportunities. J Infect Dis 2017 (published online Dec 16)

Munoz LS, Parra B, Pardo CA. Neurological implications of Zika virus infection in adults. J Infect Dis 2017 (published online Dec 16)

Parens R, Bar-Yam Y, Morales A, et al. A possible link between pyriproxyfen and microcephaly. PLoS Curr 2017 Nov 27

Satterfield-Nash A, Kotzky K, Allen J, et al. Health and development at age 19-24 months of 19 children who were born with microcephaly and laboratory evidence of congenital Zika virus infection during the 2015 Zika virus outbreak — Brazil, 2017. MMWR 2017 Dec 15;66(49):1347-51

Shiu C, Starker R, Kwal J, et al. Zika virus testing and outcomes during pregnancy, Florida, USA, 2016. Emerg Infect Dis 2017 (published online Dec 18)

Yee DA, Dejesus-Crespo R, Hunter FF, et al. Assessing natural infection with Zika virus in the southern house mosquito, Culex quinquefasciatus, during 2016 in Puerto Rico. Med Vet Entomol 2017 (published online Dec 14)

Zorrilla CD, Garcia IG, Fragoso LG, et al. Zika virus infection in pregnancy: maternal, fetal, and neonatal considerations. J Infect Dis 2017 (published online Dec 16)

Latest Cases & General Information

Zika virus (CDC landing page)

Latest Zika situation reports (WHO)

Zika virus infections and complications called Public Health Emergency of International Concern (WHO, Feb 1, 2016)

Zika virus disease, frequently asked questions about Zika virus (WHO Emergencies Preparedness, Response)

Zika virus infection (PAHO/WHO landing page)

Maps

Current Zika transmission (ECDC)

2016 Zika outbreak timeline map (HealthMap)

Pacific Disaster Center maps (updated periodically)

Zika in the United States, explained in 9 maps (Vox, Aug 4, 2016)

Zika cases in the United States (New York Times, Jul 29, 2016)

Maps predict possible Zika hot spots (USA Today, Apr 28, 2016)

Mapping global environmental suitability for Zika virus (eLife study, Apr 19, 2016)

Latest News & Commentary

Most recent CIDRAP News coverage (updated frequently)

New model for Zika virus can assist in testing vaccines and treatments (Coherent News, Dec 20)

As Zika babies become toddlers, some can’t see, walk or talk (New York Times, Dec 14)

U.S. study sheds light on how Zika causes nerve disorder (Reuters, Dec 13)

Could this zoo of mutant mosquitoes lead the way to eradicating Zika? (STAT, Dec 13)

Zika crisis (FullMeasure, Dec 10)

Responsible care in the face of shifting recommendations and imperfect diagnostics for Zika virus (Commentary in JAMA, Dec 5)

AAP releases new Red Book chapter on Zika (AAP News, Nov 30)

Drones distribute swarms of sterile mosquitoes to stop Zika and other diseases (IEEE Spectrum, Nov 20)

Assessing Zika risk in international travelers (Allison Walker, PhD, MPH, commentary on Medscape, Nov 20)

World Health Organization (WHO)

General Information

The history of Zika virus (timeline)

WHO podcast episodes 2017 (updated Mar 29, 2017)

Zika virus and potential complications: questions and answers (Mar 10, 2017)

Zika: then, now, and tomorrow (Feb 2, 2017)

Zika: we must be ready for the long haul (Feb 1, 2017, commentary from director-general Margaret Chan)

WHO Zika virus research agenda (Oct 26, 2016)

Dispelling rumours around Zika and complications (updated Sep 12, 2016)

One year into the Zika outbreak: how an obscure disease became a global health emergency (May 5, 2016)

WHO involvement in Zika R&D (Feb 8, 2016)

Zika virus outbreaks in the Americas (WHO Weekly Epidemiological Record, Nov 6, 2015)

Blood Supply

Maintaining a safe and adequate blood supply during Zika virus outbreaks, interim guidance (Feb 19, 2016)

Case Definitions

Zika virus disease: interim case definition (Feb 12, 2016)

Congenital Zika Syndrome/Fetal Infection

Fifth meeting of the Emergency Committee under the International Health Regulations (2005) regarding microcephaly, other neurological disorders and Zika virus (Nov 18, 2016)

Zika causality statement (updated Sep 7, 2016)

Assessment of infants with microcephaly in the context of Zika virus: interim guidance (updated Aug 30, 2016)

Surveillance for Zika virus infection, microcephaly and Guillain-Barre syndrome: interim guidance (Apr 7, 2016)

Zika situation report: Neurological syndrome and congenital abnormalities (Feb 5, 2016)

Diagnostics

Update on Zika diagnostic tests and WHO’s related activities (Feb 2, 2017, PLoS Negl Trop Dis policy platform)

Laboratory testing for Zika virus infection: interim guidance (Mar 23, 2016)

WHO and experts prioritize vaccines, diagnostics and innovative vector control tools for Zika R&D (Note for media, Mar 9, 2016)

Epidemiology

WHO confirms Zika virus strain imported from the Americas to Cabo Verde (May 20, 2016)

Zika virus infection — Argentina and France (Disease Outbreak News, Mar 7, 2016)

Neurologic Manifestations

Fifth meeting of the Emergency Committee under the International Health Regulations (2005) regarding microcephaly, other neurological disorders and Zika virus (Nov 18, 2016)

Guillain-Barre syndrome: fact sheet (updated October 2016)

Identification and management of Guillain-Barre syndrome in the context of Zika virus: interim guidance (updated Aug 22, 2016)

Guillain-Barre syndrome — United States of America (Disease Outbreak News, Mar 21, 2016)

Guillain-Barre syndrome — France - French Polynesia (Disease Outbreak News, Mar 7, 2016)

Zika situation report: Neurological syndrome and congenital abnormalities (Feb 5, 2016)

Guillain-Barre syndrome — El Salvador (Disease Outbreak News, Jan 21, 2016)

Outbreak Dynamics, Control

Disease Outbreak News updates

Zika situation report: Zika and potential complications (Feb 12, 2016)

Pregnancy/Breastfeeding

Breastfeeding in the context of Zika virus: interim guidance (updated Jun 29, 2016)

Pregnancy management in the context of Zika virus infection: interim guidance update (updated May 13, 2016)

Recommendations/Responses

Fifth meeting of the Emergency Committee under the International Health Regulations (2005) regarding microcephaly, other neurological disorders and Zika virus (Nov 18, 2016)

Zika strategic response plan (quarterly update, Oct 27, 2016)

Zika: strategic response plan (Jun 17, 2016)

Zika virus outbreak global response: interim report (May 27, 2016)

Zika outbreak: WHO's global emergency response plan (updated Jul 15, 2016)

Risk

Zika virus expected to spread in Europe in late spring and summer: overall risk low to moderate (May 18, 2016)

Zika virus vectors and risk of spread in the WHO European Region (Mar 18, 2016)

Zika virus risk assessment in the WHO African Region (February 2016)

Sexual and Other Non-Vector Transmission

Zika and sexual transmission (Q&A, updated Mar 10, 2017)

Prevention of sexual transmission of Zika virus: interim guidance (updated Sep 6, 2016)

Tools

WHO toolkit for the care and support of people affected by complications associated with Zika virus(Jun 18, 2017)

Zika open (Bull World Health Organ papers posted in the context of the Public Health Emergency of International Concern)

Travelers

Brazil — health advice for travellers to the 2016 Summer Olympic and Paralympic Games (updated Sep 6, 2016)

WHO public health advice regarding the Olympics and Zika virus (news release, May 28, 2016)

Vector Control/Mosquito Transmission

Vector control operations framework for Zika virus: operations framework (May 30, 2016)

Zika virus vectors and risk of spread in the WHO European Region (Mar 18, 2016)

Pan American Health Organization (PAHO)

General Information

Zika virus infection (landing page)

Zika research projects list (updated continuously)

PAHO Executive Committee briefed on Zika outbreak, advances new arbovirus control strategy (updated Mar 22, 2017)

Zika a year later: how a new virus took the Americas by surprise (updated Mar 22, 2017)

The Zika Virus outbreak continues one year after the global emergency (Feb 1, 2017)

2016: the year Zika evolved from an emergency into a long-term public health challenge (Dec 29, 2016)

PAHO director: Fight against Zika will be a ‘marathon’ (Nov 14, 2016)

Zika epidemic shows value of regional health collaboration (Sep 26, 2016)

PAHO launches database that gathers worldwide Zika virus research (updated Jun 20, 2016)

Questions and answers on vector control for Zika virus (Mar 24, 2016)

PAHO statement on Zika virus transmission and prevention (updated Feb 2, 2016)

PAHO activities on Zika prevention and control (Jan 27, 2016)

Question and Answers: Zika and pregnancy (updated Mar 25, 2016)

Community work: a key to Zika prevention in Colombia (updated Mar 15, 2016)

Congenital Zika Syndrome/Fetal Infection

PAHO/WHO updates the characterization of Zika congenital syndrome (Jul 22, 2016)

Scientists probe Zika congenital syndrome at Brazil meeting (Jul 21, 2016)

Scientists call for intensified research on Zika and microcephaly (updated Mar 7, 2016)

Neurological syndrome, congenital malformations, and Zika virus infection (Epidemiologic update, Jan 17, 2016)

Neurological syndrome, congenital malformations, and Zika virus infection. Implications for public health in the Americas (Epidemiologic alert, Dec 1, 2015)

Diagnostics

PAHO aims for faster diagnosis, more integration in combat against Zika, Dengue and Chikungunya viruses (updated Feb 18, 2016)

Epidemiology

Zika epidemiological update (updated May 25, 2017)

Zika virus infection (Epidemiologic alert, May 7, 2015)

Neurological syndrome, congenital malformations, and Zika virus infection (Epidemiologic update, Jan 17, 2016)

Neurological syndrome, congenital malformations, and Zika virus infection. Implications for public health in the Americas (Epidemiologic alert, Dec 1, 2015)

Neurologic Manifestations

Neurological syndrome, congenital malformations, and Zika virus infection (Epidemiologic update, Jan 17, 2016)

Neurological syndrome, congenital malformations, and Zika virus infection. Implications for public health in the Americas (Epidemiologic alert, Dec 1, 2015)

Recommendations/Responses

WHO and PAHO initiative to support 17 new research proposals on Zika in seven countries in Latin America and the Caribbean (Feb 23, 2017)

Cartoon Network, PAHO and UNICEF launch second phase of campaign to educate kids about preventing Zika (Feb 16, 2017)

Latin American countries conduct surveys to identify gaps in knowledge about Zika, with support from PAHO/WHO (Aug 12, 2016)

Zika ethics consultation: ethics guidance on key issues raised by the outbreak (May 23, 2016)

Cartoon Network joins PAHO, UNICEF to educate kids about preventing Zika (May 19, 2016)

Risk

Zika risk communication, community engagement focus of new prevention efforts by CDC, CDC Foundation, PAHO in U.S. Territories and the Americas (May 18, 2016)

Vector Control/Mosquito Transmission

Health leaders discuss action against mosquito-borne viruses such as Zika and dengue (Oct 21, 2016)

Caribbean Mosquito Awareness Week launched to raise awareness on preventing Zika (May 9, 2016)

Communities urged to clean up mosquito breeding sites to prevent Zika, during Vaccination Week in the Americas (Apr 28, 2016)

Scientists studying intensified vector control measures to combat Zika, dengue and chikungunya in the Americas (Mar 11, 2016)

Virus Detection

Zika virus surveillance intensifying in the Americas, but burden of disease still unclear (updated Mar 29, 2016)

PAHO, laboratories set guidelines to identify, confirm Zika virus (Feb 26, 2016)

PAHO aims for faster diagnosis, more integration in combat against Zika, Dengue and Chikungunya viruses (updated Feb 18, 2016)

As the Zika virus spreads, PAHO advises countries to monitor and report birth anomalies and other suspected complications of the virus (updated Feb 4, 2016)

US Centers for Disease Control and Prevention (CDC)

General Information

Question and answers: Zika virus infection (Zika) and pregnancy

Questions and answers for pediatric healthcare providers: Infants and Zika virus infection

Facts about microcephaly

Fact sheets and posters (in multiple languages)

Zika virus microsite (for info sharing and tracking developments)

Zika data repository on Github

Zika and animals (Jun 29, 2017)

Zika: What you need to know (updated Jun 29, 2017)

Information for parents (updated Jun 21, 2016)

Zika virus: information for clinicians (slide set, Jun 13, 2016)

CDC director addresses National Press Club (transcript, May 26, 2016—most is on Zika)

Symptoms (updated May 1, 2017)

Zika virus 101(video, Apr 7, 2017)

Prevention (updated Jan 9, 2017)

5 things you really need to know about Zika (Public Health Matters Blog, Feb 24, 2016)

Zika virus — what clinicians need to know (Jan 26, 2016)

Zika virus —10 public health achievements in 2016 and future priorities (updated Jan 5, 2017, MMWR report)

CDC highlights significant contributions in the fight against Zika in 2016 (Dec 30, 2016)

Information for specific groups (updated Dec 15, 2016)

US Zika Pregnancy Registry: what parents need to know (Apr 22, 2016)

Zika Action Plan Summit (Apr 1, 2016)

National Zika summit focused on coordinated U.S. response (news release, Apr 1, 2016)

Information for parents about Zika virus (Mar 19, 2016)

Congenital Zika Syndrome/Fetal Infection

Characteristics of dysphagia in infants with microcephaly caused by congenital Zika virus infection, Brazil, 2015. (Jun 12, 2017)

Implementing CDC guidance for infant and placental Zika virus testing and infant head ultrasound (May 5, 2017)

About 1 in 10 U.S. pregnant women with confirmed Zika infection had a fetus or baby with birth defects in 2016 (updated Apr 6, 2017)

CDC study estimates 20-fold increase in certain types of birth defects in pregnancies with possible Zika infection compared with pre-Zika years (Mar 2, 2017)

Tips for communicating with your baby's doctor or healthcare provider (Jan 17, 2017)

What to know: If your baby was born with congenital Zika syndrome (Dec 20, 2016)

CDC releases preliminary estimates of birth defects following Zika virus infection in pregnancy (Dec 15, 2016)

Study finds Zika virus replicates and persists in fetal brains and placentas (Dec 13, 2016)

Preliminary report of microcephaly potentially associated with Zika virus infection during pregnancy — Colombia, January-November 2016 (Dec 9, 2016, MMWR report)

Zika update: clinical laboratory testing and care of infants with congenital Zika virus infection (COCA call, Aug 23, 2016)

Interim guidance for the evaluation and management of infants with possible congenital Zika virus infection — United States, August 2016. (Aug 19, 2016, update)

Support for families of newborns affected by Zika (Aug 2, 2018)

CDC concludes Zika causes microcephaly and other birth defects (media statement, Apr 13, 2016)

Diagnostics

Understanding Zika virus test results (updated May 10, 2017)

Testing for Zika virus (including for pregnancy, updated Feb 28, 2018)

Zika update: clinical laboratory testing and care of infants with congenital Zika virus infection (COCA call, Aug 23, 2016)

Zika diagnostic tools, testing algorithms, and interpretation guidance (Jun 13, 2016)

Diagnostic testing of urine specimens for suspected Zika virus infection (HAN advisory, May 25, 2016)

Recognizing, managing, and reporting Zika virus infections in travelers returning from Central America, South America, the Caribbean, and Mexico (Health Advisory, Jan 15, 2016)

Revised diagnostic testing for Zika, chikungunya, and dengue viruses in US Public Health Laboratories (memo, Jan 7, 2016)

CDC scientists use AMD methods to develop diagnostic tools for Zika virus (Feb 3, 2016, fact sheet)

Epidemiology

CDC supporting Texas investigation of possible local Zika transmission (Nov 28, 2016)

Florida investigation links four recent Zika cases to local mosquito-borne virus transmission (Jul 29, 2016)

Zika infections increasing rapidly in Puerto Rico (Jul 29, 2016)

Possible Zika virus infection among pregnant women — United States and territories, May 2016 (MMWR report, May 20, 2016)

Funding

CDC awards nearly $184 million to continue the fight against Zika (Dec 22, 2016)

CDC announces supplemental funding opportunity for continued Zika response in 2017 (Oct 21, 2016)

CDC awards $13 million to establish the first Vector Control Unit in Puerto Rico (Sep 27, 2016)

CDC awards $2.4 million to five jurisdictions to fight Zika (Sep 2, 2016)

CDC awards $6.8 million to partners to support Zika response (Aug 24, 2016)

CDC continues to support Florida in response to Zika outbreak (Aug 24, 2016)

CDC awards $16 million to states and territories to fight Zika (Aug 2, 2016)

CDC awards $60 million to help states and territories battle Zika (Jul 21, 2016)

CDC awards funds for states and territories to prepare for Zika (Jul 1, 2016)

Guidance

CDC updates Zika guidance for Miami-Dade County, Florida (updated Jun 30, 2017)

Implementing CDC guidance for infant and placental Zika virus testing and infant head ultrasound (May 5, 2017)

CDC updates guidance on interpretation of Zika testing results for pregnant women (May 5, 2017)

CDC updates Zika travel guidance for pregnant women to not travel to any area with Zika risk (Mar 10, 2017)

CDC adds 4 countries to interim travel guidance related to Zika virus (Mar 10, 2017)

CDC issues Zika virus guidance for Brownsville, Texas (Dec 14, 2016)

CDC updates Zika guidance for South Miami Beach (FL) area (Dec 9, 2016)

CDC updates guidance for Little River (FL) area with active Zika transmission (Dec 2, 2016)

CDC updates guidance for Miami Beach (FL) area with active Zika transmission (Nov 22, 2016)

Guidance for U.S. laboratories testing for Zika virus infection (updated Nov 16, 2016)

Zika virus response planning: interim guidance for district and school administrators in the continental United States and Hawaii (Oct 20, 2016)

CDC updates guidance related to local Zika transmission in Miami-Dade County, Florida (Oct 19, 2016)

CDC updates guidance for pregnant women and women and men of reproductive age for Zika virus infection related to the ongoing investigation of local mosquito-borne Zika virus transmission in Miami-Dade County, Florida (HAN notice, Oct 19, 2016)

CDC updates interim guidance for pre-pregnancy counseling and prevention of sexual transmission of Zika (Sep 30, 2016)

CDC updates guidance for travel and testing of pregnant women and women of reproductive age for Zika virus infection related to the ongoing investigation of local mosquito-borne Zika virus transmission in Miami-Dade County, Florida (HAN notification, Sep 20, 2016)

CDC updates guidance for Wynwood (FL) neighborhood with active Zika transmission (Sep 19, 2016)

CDC expands guidance for travel and testing of pregnant women, women of reproductive age, and their partners for Zika virus infection related to mosquito-borne Zika virus transmission in Miami-Dade, Florida (HAN advisory, Aug 19, 2016)

Interim guidance for the evaluation and management of infants with possible congenital Zika virus infection — United States, August 2016. (Aug 19, 2016, update)

Resources and guidance for healthcare providers caring for infants affected by Zika virus (Nov 27, 2017)

CDC issues travel guidance related to Miami neighborhood with active Zika spread (Aug 1, 2016)

CDC guidance for travel and testing of pregnant women and women of reproductive age for Zika virus infection related to the investigation for local mosquito-borne Zika virus transmission in Miami-Dade and Broward Counties, Florida (Health Alert Network notice, Aug 1, 2016)

CDC issues updated Zika recommendations: interim guidance for healthcare providers caring for pregnant women with possible exposure to Zika virus; interim guidance for the prevention of sexually transmitted Zika virus (Jul 25, 2016)

Interim guidance for interpretation of Zika virus antibody test results (MMWR report, May 31, 2016)

Interim guidance for protecting workers from occupational exposure to Zika virus (CDC/OSHA, Apr 22, 2016)

Interim guidance for prevention of sexual transmission of Zika virus — United States, 2016. (MMWR, Mar 25, 2016)

Interim guidance for health care providers caring for women of reproductive age with possible Zika virus exposure — United States, 2016. (MMWR, Mar 25, 2016)

Laboratory safety when working with Zika virus. (April 27, 2017)

Zika response for states (Jul 31, 2018)

CDC encourages following guidance to prevent sexual transmission of Zika virus (media statement, Feb 23, 2016)

Neurologic Manifestations

Facts about microcephaly

About 1 in 10 U.S. pregnant women with confirmed Zika infection had a fetus or baby with birth defects in 2016 (updated Apr 6, 2017)

CDC study estimates 20-fold increase in certain types of birth defects in pregnancies with possible Zika infection compared with pre-Zika years (Mar 2, 2017)

What to know: If your doctor suspects microcephaly during pregnancy (Dec 20, 2016)

Preliminary report of microcephaly potentially associated with Zika virus infection during pregnancy — Colombia, January-November 2016 (Dec 9, 2016, MMWR report)

CDC concludes Zika causes microcephaly and other birth defects (media statement, Apr 13, 2016)

Increase in reported prevalence of microcephaly in infants born to women living in areas with confirmed Zika virus transmission during the first trimester of pregnancy — Brazil, 2015 (MMWR, Mar 8, 2016)

Outbreak Dynamics, Control

CDC, Miami-Dade and Miami Beach collaborate and make progress on better understanding and stopping the Zika outbreak (Oct 27, 2016)

CDC working with Florida to respond to new active Zika transmission area in Miami-Dade County (Oct 14, 2016)

CDC works with Florida as Miami Beach active Zika transmission area expands (Sep 17, 2016)

Additional area of active Zika transmission identified in Miami Beach (Aug 19, 2016)

Pregnancy/Breastfeeding

Question and answers: Zika virus infection (Zika) and pregnancy

Testing pregnant women (updated Aug 3, 2018)

CDC updates guidance on interpretation of Zika testing results for pregnant women (May 5, 2017)

Zika virus: protecting pregnant women and babies (digital press kit, Apr 4, 2017)

CDC updates Zika travel guidance for pregnant women to not travel to any area with Zika risk (Mar 10, 2017)

Zika virus and pregnancy (grand round presentation, Jan 30, 2017)

Zika virus testing: For pregnant women who may have been exposed to Zika 2-12 weeks ago (Jan 10, 2017)

Zika virus testing: For pregnant women living in an area with Zika (Jan 10, 2017)

Zika virus testing: For pregnant women who may have been exposed to Zika within the past 2 weeks (Jan 10, 2017)

Evidence that microcephaly risk is highest among pregnant women infected early in pregnancy (Dec 9, 2016)

CDC updates guidance for pregnant women and women and men of reproductive age for Zika virus infection related to the ongoing investigation of local mosquito-borne Zika virus transmission in Miami-Dade County, Florida (HAN notice, Oct 19, 2016)

CDC updates guidance for travel and testing of pregnant women and women of reproductive age for Zika virus infection related to the ongoing investigation of local mosquito-borne Zika virus transmission in Miami-Dade County, Florida (HAN notification, Sep 20, 2016)

CDC expands guidance for travel and testing of pregnant women, women of reproductive age, and their partners for Zika virus infection related to mosquito-borne Zika virus transmission in Miami-Dade, Florida (HAN advisory, Aug 19, 2016)

CDC guidance for travel and testing of pregnant women and women of reproductive age for Zika virus infection related to the investigation for local mosquito-borne Zika virus transmission in Miami-Dade and Broward Counties, Florida (Health Alert Network notice, Aug 1, 2016)

Pregnant women: how to protect yourself (updated Jul 28, 2016)

CDC issues updated Zika recommendations: interim guidance for healthcare providers caring for pregnant women with possible exposure to Zika virus; interim guidance for the prevention of sexually transmitted Zika virus (Jul 25, 2016)

CDC begins reporting pregnancy and birth outcomes of women affected by Zika virus during pregnancy (Jun 16, 2016)

CDC changes reporting of numbers of pregnant women affected by Zika virus (May 20, 2016)

The Strategic National Stockpile's unique role in Zika prevention (Public Health Matters Blog, May 9, 2016)

Zika and pregnancy: what you should know (updated Apr 1, 2016)

Zika and sex: Information for pregnant women living in areas with Zika (Fact sheet, Mar 14, 2016)

For pregnant women in areas with Zika: Protect your pregnancy (Fact sheet, Aug 3, 2017)

Increase in reported prevalence of microcephaly in infants born to women living in areas with confirmed Zika virus transmission during the first trimester of pregnancy — Brazil, 2015 (MMWR, Mar 8, 2016)

Zika virus infection among U.S. pregnant travelers — August 2015–February 2016. (MMWR, Feb 26, 2016)

Recommendations/Responses

Advice for people living in or traveling to South Florida (updated Jun 2, 2017)

Guidance for areas with a previous Zika cautionary (yellow) designation in the continental United States and Hawaii (Jun 1, 2017)

CDC Zika sustainment strategy presentation: overview (May 10, 2017)

CDC Zika interim response plan (updated May 5, 2017)

CDC and the Instituto Nacional de Salud of Colombia collaborate to understand long-term effects of Zika virus infection during pregnancy (Sep 2, 2016)

CDC issues updated Zika recommendations: interim guidance for healthcare providers caring for pregnant women with possible exposure to Zika virus; interim guidance for the prevention of sexually transmitted Zika virus (Jul 25, 2016)

U.S. Centers for Disease Control and Prevention and Environmental Protection Agency urge Commonwealth of Puerto Rico to consider aerial spraying as part of integrated mosquito control to reduce Zika-associated birth defects (Jul 6, 2016)

CDC recommendations for subsequent Zika IgM antibody testing (Health Alert Network, Jun 21, 2016)

Zika: CDC draft interim response plan (Jun 14, 2016)

CDC issues advice for travel to the 2016 Summer Olympic Games (Feb 26, 2016)

Risk

CDC identifies potential risk of Zika virus transmission since June 15, 2016, in Miami-Dade, Broward, and Palm Beach counties (Mar 13, 2017)

Evidence that microcephaly risk is highest among pregnant women infected early in pregnancy (Dec 9, 2016)

Healthcare exposure to Zika and infection control (Oct 21, 2016)

Sexual and Other Non-Vector Transmission

Sexual transmission and prevention (updated Aug 2, 2017)

CDC assisting Utah investigation of Zika virus infection apparently not linked to travel (Jul 18, 2016)

First female-to-male sexual transmission of Zika virus infection reported in New York City (Jul 15, 2016)

Estimating contraceptive needs and increasing access to contraception in response to the Zika virus disease outbreak — Puerto Rico, 2016. (MMWR, Mar 25, 2016)

Interim guidance for prevention of sexual transmission of Zika virus — United States, 2016. (MMWR, Mar 25, 2016)

Preventing transmission of Zika virus in labor and delivery settings through implementation of standard precautions — United States, 2016. (MMWR, Mar 22, 2016)

Zika and sex: Information for men with pregnant partners living in areas with Zika (Fact sheet, Mar 14, 2016)

Zika and sex: Information for pregnant women living in areas with Zika (Fact sheet, Mar 14, 2016)

Transmission of Zika virus through sexual contact with travelers to areas of ongoing transmission — continental United States, 2016. (MMWR, Feb 26, 2016)

Update: Interim guidelines for prevention of sexual transmission of Zika virus — United States, 2016 (Health Alert Network advisory, Feb 23, 2016)

CDC encourages following guidance to prevent sexual transmission of Zika virus (media statement, Feb 23, 2016)

Serology

Prolonged IgM antibody response in people infected with Zika virus: implications for interpreting serologic testing results for pregnant women (Health Alert Network, May 5, 2017)

Tools

Fact sheets and posters (in multiple languages)

Toolkit for investigating possible local mosquito-borne transmission of Zika virus (May 5, 2017

Symptoms (updated May 1, 2017)

Healthcare provider toolkit: for obstetricians (Jan 20, 2017)

Healthcare provider toolkit: for pediatricians (Jan 20, 2017)

Pregnancy & Zika testing Web tool (updated Jan 30, 2017)

Zika virus: a primer for nurses (grand round presentation, Jan 30, 2017)

Zika virus and pregnancy (grand round presentation, Jan 30, 2017)

Zika and infants: a primer (grand round presentation, Jan 30, 2017)

Zika training for healthcare providers (updated Jan 18, 2017)

What to know: If your baby may have been affected by Zika but has no related health conditions at birth (Dec 15, 2016)

What to know: If your baby was born with congenital Zika syndrome (Dec 20, 2016)

What to know: If your doctor suspects microcephaly during pregnancy (Dec 23, 2016)

Zika in the ED: how emergency care staff can take action (Nov 1, 2016, COCA call)

Zika is in your area: what to do (Aug 1, 2016)

Pregnant women: how to protect yourself (updated Jul 28, 2016)

Build your own Zika prevention kit (updated Jul 1, 2016)

Tools for health care providers (updated Dec 14, 2017

Travelers

Travel health notices

Zika travel information (updated Jun 29, 2017)

Advice for people living in or traveling to South Florida (updated Jun 2, 2017)

CDC adds 4 countries to interim travel guidance related to Zika virus (Mar 10, 2017)

CDC updates Zika travel guidance for pregnant women to not travel to any area with Zika risk (Mar 10, 2017)

CDC updates guidance for pregnant women and women and men of reproductive age for Zika virus infection related to the ongoing investigation of local mosquito-borne Zika virus transmission in Miami-Dade County, Florida (HAN notice, Oct 19, 2016)

CDC issues Zika special travel considerations for 11 Southeast Asian countries (Sep 29, 2016)

CDC updates guidance for travel and testing of pregnant women and women of reproductive age for Zika virus infection related to the ongoing investigation of local mosquito-borne Zika virus transmission in Miami-Dade County, Florida (HAN notification, Sep 20, 2016)

CDC expands guidance for travel and testing of pregnant women, women of reproductive age, and their partners for Zika virus infection related to mosquito-borne Zika virus transmission in Miami-Dade, Florida (HAN advisory, Aug 19, 2016)

CDC issues travel guidance related to Miami neighborhood with active Zika spread (Aug 1, 2016)

CDC guidance for travel and testing of pregnant women and women of reproductive age for Zika virus infection related to the investigation for local mosquito-borne Zika virus transmission in Miami-Dade and Broward Counties, Florida (Health Alert Network notice, Aug 1, 2016)

CDC models risk of Zika virus importation resulting from travel to the 2016 Olympic and Paralympic Games (Jul 13, 2016)

Revision to CDC's Zika travel notices: minimal likelihood for mosquito-borne Zika virus transmission at elevations above 2,000 meters. (MMWR, Mar 11, 2016)

Zika virus infection among U.S. pregnant travelers — August 2015–February 2016. (MMWR, Feb 26, 2016)

Transmission of Zika virus through sexual contact with travelers to areas of ongoing transmission — continental United States, 2016. (MMWR, Feb 26, 2016)

CDC issues advice for travel to the 2016 Summer Olympic Games (Feb 26, 2016)

Recognizing, managing, and reporting Zika virus infections in travelers returning from Central America, South America, the Caribbean, and Mexico (Health Advisory, Jan 15, 2016)

Vector Control/Mosquito Transmission

CDC surveys find increase in the number of U.S. counties with Aedes aegypti and Aedes albopictus mosquitoes that can spread Zika (Jun 20, 2017)

Toolkit for investigating possible local mosquito-borne transmission of Zika virus (May 5, 2017

CDC awards $13 million to establish the first Vector Control Unit in Puerto Rico (Sep 27, 2016)

Florida health officials report on response to Zika in Wynwood; evidence shows aerial spraying likely helped interrupt local transmission (Sep 23, 2016)

Florida investigation links four recent Zika cases to local mosquito-borne virus transmission (Jul 29, 2016)

U.S. Centers for Disease Control and Prevention and Environmental Protection Agency urge Commonwealth of Puerto Rico to consider aerial spraying as part of integrated mosquito control to reduce Zika-associated birth defects (Jul 6, 2016)

The Strategic National Stockpile's unique role in Zika prevention (Public Health Matters Blog, May 9, 2016)

Preparing for local mosquito-borne transmission of Zika virus — United States, 2016. (MMWR, Apr 1, 2016)

Zika, mosquitoes, and standing water (Public Health Matters Blog, Mar 22, 2016)

Revision to CDC's Zika travel notices: minimal likelihood for mosquito-borne Zika virus transmission at elevations above 2,000 meters. (MMWR, Mar 11, 2016)

Virus Detection

Testing pregnant women (updated Aug 3, 2018)

Implementing CDC guidance for infant and placental Zika virus testing and infant head ultrasound (May 5, 2017)

CDC updates guidance on interpretation of Zika testing results for pregnant women (May 5, 2017)

CDC and Thailand partnership improves lab testing for Zika virus (Mar 27, 2017)

Guidance for U.S. laboratories testing for Zika virus infection (updated Nov 16, 2016)

Testing for Zika virus (including for pregnancy, updated May 24, 2018)

CDC continues to build US laboratory capacity to rapidly detect Zika virus infection (Sep 20, 2016)

Zika update: clinical laboratory testing and care of infants with congenital Zika virus infection (COCA call, Aug 23, 2016)

Collecting and submitting specimens at time of birth for Zika virus testing (Feb 27, 2018)

Collecting and submitting placental and fetal tissue specimens for Zika virus testing (Aug 8, 2018)

Triple testing: CDC works rapidly to develop unprecedented Zika test (Aug 16, 2016)

Diagnostic testing of urine specimens for suspected Zika virus infection (HAN advisory, May 25, 2016)

CDC changes reporting of numbers of pregnant women affected by Zika virus (May 20, 2016)

New CDC laboratory test for Zika virus authorized for emergency use by FDA (Feb 26, 2016)

Virus Traits/Structure/Mutations/Actions

Prolonged IgM antibody response in people infected with Zika virus: implications for interpreting serologic testing results for pregnant women (Health Alert Network, May 5, 2017)

Study finds Zika virus replicates and persists in fetal brains and placentas (Dec 13, 2016)

Zika and Other Pathogens

West Nile to Zika: how one virus helped New York City prepare for another (Public Health Matters Blog, Sep 12, 2016)

Triple testing: CDC works rapidly to develop unprecedented Zika test (Aug 16, 2016)

Revised diagnostic testing for Zika, chikungunya, and dengue viruses in US Public Health Laboratories (memo, Jan 7, 2016)

Government of Canada

Zika virus (landing page)

Public health notice — Zika virus (Public Health Agency of Canada [PHAC])

Zika virus infection in the America (Travel health notice, PHAC)

European Centre for Disease Prevention and Control (ECDC)

General Information

Zika virus infection (landing page)

Current Zika virus transmission — list of countries: ECDC adaptation of WHO's Zika virus country classification scheme (Jun 29, 2017)

Recent scientific findings based on literature reviewed after the ninth update of the ECDC Rapid Risk Assessment on Zika virus infection (19 October to 27 January 2017) (Feb 6, 2017)

Recent scientific findings based on literature reviewed after the eighth update of the ECDC Rapid Risk Assessment on Zika virus infection (Oct 28, 2016)

Infographic: How is Zika virus transmitted? (Aug 26, 2016)

Zika virus and safety of substances of human origin (Jul 15, 2016)

Epidemiology

Outbreaks of Zika virus and complications potentially linked to the Zika virus infection (epidemiologic update, Jul 21, 2016)

Outbreaks of Zika virus and complications potentially linked to the Zika virus infection (epidemiologic update, Jun 23, 2016)

Outbreaks of Zika virus and complications potentially linked to the Zika virus infection (Feb 4, 2016, epidemiologic update)

Neurologic Manifestations

The Zika epidemic and association to microcephaly and Guillain-Barre (updated risk assessment, Jul 11, 2016)

Microcephaly in Brazil potentially linked to the Zika virus epidemic, ECDC assesses the risk (Nov 24, 2015)

Tools

Zika virus and safety of substances of human origin (Jul 15, 2016)

Recommendations/Responses

Preparing for Zika in the EU – policy briefing (Jun 26, 2016)

Zika virus disease epidemic: preparedness planning guide for diseases transmitted by Aedes aegypti and Aedes albopictus (Apr 8, 2016)

Risk

The Zika epidemic and association to microcephaly and Guillain-Barre (updated risk assessment, Jul 11, 2016)

Accumulating evidence on Zika virus disease and potential link to severe outcomes (Rapid risk assessment, Apr 12, 2016)

Microcephaly in Brazil potentially linked to the Zika virus epidemic, ECDC assesses the risk (Nov 24, 2015)

Zika virus infection outbreak, French Polynesia (Rapid risk assessment, updated Feb 14, 2014)

United Nations

A socio-economic impact assessment of the Zika virus in Latin America and the Caribbean: with a focus on Brazil, Colombia and Suriname (Apr 3, 2017)

Zika could end up costing Latin America and the Caribbean up to $18 billion, UN report finds (Apr 6, 2017)

The human rights dimensions of Zika (commentary by Alexandra Phelan & Lawrence Gostin, Apr 4, 2016)

UNICEF

ZIKV diagnostics request for proposal launched; $10 million advance purchase commitment created (Feb 28, 2017)

Public Health England (PHE)

The characteristics, symptoms, diagnosis and epidemiology of Zika (landing page)

London School of Hygiene and Tropical Medicine

Web page

New Zealand Ministry of Health

Zika virus (landing page)

Zika virus: updated travel advice for pregnant women (Mar 1, 2016)

US National Institutes of Health (NIH)

Study to examine effects of Zika infection in Guatemalan infants and children (Jun 19, 2017)

Zika virus (Sep 8, 2017)

Zika virus and older adults (Nov 8, 2016)

NIH begins testing investigational Zika vaccine in humans (Aug 3, 2016)

NIH funds Zika virus study involving U.S. Olympic team (Jul 5, 2016)

NIH launches large study of pregnant women in areas affected by Zika virus (Jun 21, 2016)

Zika’s potential threat to world blood supply deserves study — and action (Jun 14, 2016)

Snapshots of life: portrait of Zika virus (NIH Director’s Blog, May 19, 2016)

Zika and birth defects: the evidence mounts (NIH Director’s Blog, Mar 15, 2016)

NIH seeks research applications to study Zika in pregnancy, developing fetus (Feb 5, 2016)

Zika virus: an emerging health threat (NIH Director’s blog, Jan 26, 2016)

Notice of NIAID's interest to highlight high-priority Zika virus (ZIKV) research areas (Jan 22, 2016)

US Health and Human Services (HHS)

General information

Zika virus health information resources (Disaster Information Management Research Center, updated daily)

Zika: resources at your fingertips (updated monthly)

Ensuring a coordinated response to Zika and other public health threats (Dec 5, 2016, ASPR Blog)

Here’s what you need to know about the Zika virus (Secretary Burwell, Jul 25, 2016)

Diagnostics

HHS funds development of Zika diagnostic test for use in doctors' offices (Aug 25, 2016)

HHS awards $7 million to OraSure to speed development of Zika diagnostic test (Aug 23, 2016)

HHS awards $2.6 million to DiaSorin Group to develop rapid, high-capacity Zika diagnostic laboratory test (Aug 22, 2016)

HHS helping lift key hurdle in the efforts to develop better Zika diagnostics (Apr 27, 2016)

Funding

Zika supplemental funding spend plan (Oct 26, 2016)

HHS awards $350,000 to American Academy of Pediatrics to help children affected by the Zika virus (Sep 8, 2016)

HHS funds development of Zika diagnostic test for use in doctors' offices (Aug 25, 2016)

HHS awards $7 million to OraSure to speed development of Zika diagnostic test (Aug 23, 2016)

HHS awards $2.6 million to DiaSorin Group to develop rapid, high-capacity Zika diagnostic laboratory test (Aug 22, 2016)

HHS awards more than $742,000 to health centers in American Samoa and the Virgin Islands to fight Zika (Jun 23, 2016)

HHS awards $5 million to Puerto Rico health centers to fight the spread of Zika virus (Apr 26, 2016)

Travelers

Take precautions to avoid Zika virus infection during trips abroad (ASPR Blog, Jul 6, 2016)

Vaccines

HHS accelerates development of mRNA-based Zika vaccine (Sep 7, 2016)

HHS calls on center for innovation to accelerate Zika vaccine development (Jun 27, 2016)

US Food and Drug Administration (FDA)

Zika Virus Response Updates from FDA (landing page)

FDA provides new tools for the development and proper evaluation of tests for detecting Zika virus infection (Aug 17, 2017)

ZIKV Detect IgM Capture ELISA by InBios International, Inc: FDA safety communication — wait for confirmatory test results before making patient management decisions (Dec 23, 2016)

Statement from Peter Marks, M.D., Ph.D., Director, FDA’s Center for Biologics Evaluation and Research (on blood screening, Jul 28, 2016)

FDA takes action against Zika virus (FDA Voice blog, Jul 12, 2016)

FDA allows use of investigational test to screen blood donations for Zika virus (news release, Mar 30, 2016)

FDA issues recommendations to reduce the risk of Zika virus transmission by human cell and tissue products (news release, Mar 1, 2016)

Emergency Use Authorization for Zika test (Feb 26, 2016)

US White House

Remarks by the president on the Zika virus (Jul 1, 2016)

The private sector is stepping up to combat the Zika virus—Congress should too (blog post, Jun 6, 2016)

Taking every step necessary, as quickly as possible, to protect the American people from Zika (blog post, Apr 6, 2016)

Preparing for and responding to the Zika virus at home and abroad (fact sheet, Feb 8, 2016)

US National Institute for Occupational Safety and Health (NIOSH)

Zika virus: key worker resources

US Congressional Research Service

Zika virus in Latin America and the Caribbean: U.S. policy considerations (Jun 29, 2016)

Zika response funding: request and congressional action (May 20, 2016)

Zika response funding: in brief (Apr 14, 2016)

Zika virus: global health considerations (CRS Insight, Feb 9, 2016)

US Government Accountability Office (GAO)

Preliminary observations on the Zika virus outbreak (Mar 2, 2016)

US Department of Agriculture (USDA)



USDA-ARS researchers are controlling mosquitoes naturally (video, Sep 26, 2017)

US Department of Defense

Walter Reed scientists test Zika vaccine candidate (Jun 9, 2016)

DoD adds funding to enhance Zika surveillance by military labs (May 16, 2016)

USAID

Combatting Zika and future threats: a grand challenge for development (Apr 13, 2016)

Institute of Medicine

Potential research priorities to inform public health and medical practice for domestic Zika virus (workshop brief, Feb 29, 2016)

Research priorities to inform public health and medical practice for domestic Zika Virus: a workshop (National Academies meeting video, Feb 16, 2016)

Public Health Emergency (US)

Promoting stress management for pregnant women during the Zika virus disease outbreak (Jun 29, 2016)

Resources in Affected Countries

CIDRAP-compiled list of health ministry links for affected countries

Resources from Journals, News Organizations

Zika virus detection and sexual transmission (Euro Surveill collection)

Zika reports (MMWR)

Zika virus (N Engl J Med)

Zika virus resource centre (Lancet)

Zika virus: free articles by discipline (Springer/Nature)

Zika virus resource center (Elsevier)

Zika virus: full coverage (USA Today)

Zika virus (BMJ)

Zika in 30 seconds: what you need to know today (STAT News)

Zika virus (Elsevier)

Zika virus outbreak (NBC News)

Reuters focus: the Zika virus

Zika virus disease (JAMA patient page, Jun 14, 2016)

Zika virus infection (compilation of Eurosurveillance articles on Zika)

Zika virus resources (PLoS Collections)

Zika virus resource page (Science Open)

Zika spotlight (Emerging Infectious Diseases articles, 2007-2016)

Zika virus in pregnancy: where to find useful guidance (BJOG)

Zika: a clinical guide (BMJ)

American Public Health Association (APHA)

New Zika virus chapter updates 'Control of Communicable Diseases Manual' (News release, May 11, 2016)

Association of Public Health Laboratories (APHL)

3 Zika tests explained (Aug 5, 2016)

American Medical Association (AMA)

Zika virus resource center

American Society for Microbiology (ASM)

Zika virus resources

American Congress of Obstetricians and Gynecologists (ACOG)

Zika virus

Practice advisory on Zika virus (Aug 3, 2016, with SMFM)

American Academy of Pediatrics

Zika virus: psychosocial support videos (Apr 2017)

Wellcome Trust

The ethics of Zika trials in pregnancy (blog post, Apr 14, 2016)

Zika: Why now and what next? (video, Mar 1, 2016)

What we need to find out about Zika and pregnancy (Feb 18, 2016)

Zika: Q&A with the infectious disease expert (Feb 16, 2016)

Sharing data during Zika and other global health emergencies (Feb 10, 2016)

Zika virus outbreak in the Americas (Feb 1, 2016, blog post)

Taking action on Zika (Feb 2, 2016, blog post)

Zika: Q&A with the mapping expert (Feb 23, 2016)

Global Health Network, Fiocruz Institute (Brazil)

Zika infection

ReliefWeb

Zika virus infection: step-by-step guide to risk communication and community engagement (Jan 13, 2017)

March of Dimes

Zika Care Connect

New York University

U.S. public's perception of Zika risk: awareness, knowledge, and receptivity to public health interventions (Oct 28, 2016)

Johns Hopkins University

Hearing Notes: U.S. public health response to the Zika virus — continuing challenges (Bifurcated Needle blog, May 30, 2017)

The Zika virus: emerging data, uncertainty, and response (Bloomberg School of Public Health video, May 23, 2017)

What you need to know about Zika virus | Pregnancy and sexual transmission (video, Apr 4, 2016)

UpToDate

Zika virus infection: an overview

Global Virus Network

GVN launches Zika Task Force (Feb 16, 2016)

MPHonline

Bitten: Zika virus 101 (infographic)

Center for Infectious Disease Modeling and Analysis (CIDMA)

A cost-effectiveness tool for informing policies on Zika control

Pregnancy Research Ethics for Vaccines, Epidemics, and New Technologies (PREVENT)

Pregnant women & the Zika virus vaccine research agenda: ethics guidance on priorities, inclusion, and evidence generation (Jun 2017)

National Association of County & City Health Officials (NACCHO)

Mosquito control capabilities in the U.S. (report, Oct 2017)

Shifting our approach to mosquito control capabilities in the U.S. (Oct 16, 2017)

Summer is here and so are the mosquitoes: why local vector control is key to combating Zika (Jul 31, 2017)

Twitter

CIDRAP (@CIDRAP)

PAHO-WHO (@pahowho)

World Health Organization (@WHO)

ECDC (@ECDC_EU)

Tom Frieden, MD, MPH (@DrFrieden)

Helen Branswell (@HelenBranswell)

Ian M Mackay, PhD (@MackayIM)

Lisa Schnirring (@lisaschnirring)

Michael Coston (@Fla_Medic)

Crawford Kilian (@crof)

Maryn McKenna (@marynmck)

Delthia Ricks (@DelthiaRicks)

Laurie Garrett (@Laurie_Garrett)

Martin Enserink (@martinenserink)

Jon Cohen (@sciencecohen)

Greg Folkers, MPH (@greg_folkers)

Maia Majumder, MPH (@maiamajumder)

Tara C. Smith, PhD (@aetiology)

Peter J. Hotez, MD (@PeterHotez)

Michael Edelstein, MbChB (@epi_michael)

Judy Stone, MD (@DrJudyStone)

Jeremy Farrar, MD (@JeremyFarrar)

Selected Reading

2017

General Information

Ali S, Gugliemini O, Harber S, et al. Environmental and social change drive the explosive emergence of Zika virus in the Americas. PLoS Negl Trop Dis 2017 Feb 9;11(2):e0005135

Baud D, Gubler DJ, Schaub B, et al. An update on Zika virus infection. Lancet 2017 (published online Jun 21)

Bierle CJ, Fernandez-Alarcon C, Hernandez-Alvarado N, et al. Assessing Zika virus replication and the development of Zika-specific antibodies after a mid-gestation viral challenge in guinea pigs. PLoS One 2017 Nov 3;12(11):e0187720

Carlson CJ, Dougherty E, Boots M, et al. Consensus and conflict among ecological forecasts of Zika virus outbreaks in the United States. bioRxiv 2017 Nov 14

Cheema S, Maisonneuve P, Weber I, et al. Knowledge and perceptions about Zika virus in a Middle East country. BMC Infect Dis 2017 (published online Jul 26)

Coimbra BM, Coelho FC, Armstrong M, et al. Zika: an ongoing threat to women and infants. bioRxiv 2017 Nov 16

Colon-Gonzalez FJ, Peres CA, Bernardo CSS, et al. After the epidemic: Zika virus projections for Latin America and the Caribbean. PLoS Negl Trop Dis 2017 Nov 1;11(11):e0006007

GAO (US Government Accountability Office). Emerging infectious diseases: actions needed to address the challenges of responding to Zika virus disease outbreaks. GAO-17-445. May 23, 2017

Goldfarb IT, Jaffe E, Lyerly AD. Responsible care in the face of shifting recommendations and imperfect diagnostics for Zika virus. JAMA 2017 (published online Oct 27)

Gregory CJ, Oduyebo T, Brault AC, et al. Modes of transmission of Zika virus. J Infect Dis 2017 (published online Dec 16)

He D, Gao D, Lou Y, et al. A comparison study of Zika virus outbreaks in French Polynesia, Colombia and the state of Bahia in Brazil. Sci Rep 2017 (published online Mar 21)

Hilgard J, Jamieson KH. Does a scientific breakthrough increase confidence in science? News of a Zika vaccine and trust in science. Sci Commun 2017 (published online Jul 25)

J Infect Dis. Zika virus: a new threat emerges. (Special supplement) J Infect Dis 2017 Dec;216(suppl 10)

Kalkeri R, Murthy KK. Zika virus reservoirs: implications for transmission, future outbreaks, drug and vaccine development. F1000Res 2017 (published online Oct 17)

Krow-Lucal ER, Biggerstaff BJ, Staples JE. Estimated incubation period for Zika virus disease. Emerg Infect Dis 2017 (published online Mar 10)

Leder K, Grobusch MP, Gautret P, et al. Zika beyond the Americas: travelers as sentinels of Zika virus transmission. A GeoSentinel analysis, 2012 to 2016. PLoS One 2017 Oct 3;12(10):e0185689

Ortiz MR, Le NK, Sharma V, et al. Post-earthquake Zika virus surge: disaster and public health threat amid climatic conduciveness. Sci Rep 2017 (published online Nov 13)

Painter JE, Plaster AN, Tjersland DH, et al. Zika virus knowledge, attitudes, and vaccine interest among university students. Vaccine 2017 (published online Jan 6)

Prue CE, Roth Jr. JN, Garcia-Williams A, et al. Awareness, beliefs, and actions concerning Zika virus among pregnant women and community members — U.S. Virgin Islands, November-December 2016. MMWR 2017 Aug 31;66(34):909-13

Simkins J, Anjan S, Morillas-Rodriquez JA, et al. Screening for Zika virus in deceased organ donors in Florida. Am J Transplant 2017 (published online Nov 8)

Sorensen CJ, Borbor-Cordova MJ, Calvello-Hynes, et al. Climate variability, vulnerability and natural disasters: a case study of Zika virus in Manabi, Ecuador following the 2016 earthquake. GeoHealth 2017 (published online Oct 12)

Subissi L, Daudens-Vaysse E, Cassadou S, et al. Revising rates of asymptomatic Zika virus infections based on sentinel surveillance data from French overseas territories. Int J Infect Dis 2017 (published online Oct 25)

Yung CF, Tam CC, Rajadurai VS, et al. Rapid assessment Zika virus knowledge among clinical specialists in Singapore: a cross-sectional survey. PLoS Curr 2017 May 3

Wu Y, Cui X, Wu N, et al. A unique case of human Zika virus infection in association with severe liver injury and coagulation disorders. Sci Rep 2017 (published online Sep 12)

Antiviral Response/Candidates

Albulescu IC, Kovacikova K, Tas A, et al. Suramin inhibits Zika virus replication by interfering with virus attachment and release of infectious particles. Antiviral Res 2017 (published online Apr 28)

Best K, Guedj J, Madelain V, et al. Zika plasma viral dynamics in nonhuman primates provides insights into early infection and antiviral strategies. Proc Natl Acad Sci USA 2017 (published online Aug 1)

Boldescu V, Behnam MAM, Vasilakis N, et al. Broad-spectrum agents for flaviviral infections: dengue, Zika and beyond. Nat Rev Drug Discov 2017 (published online May 5)

Costa VV, Del Sarto JL, Rocha RF, et al. N-methyl-d-aspartate (NMDA) receptor blockade prevents neuronal death induced by Zika virus infection. mBio 2017 Apr 25;8(2):e00350-17

Estoppey D, Lee CM, Janoschke, et al. The natural product cavinafungin selectively interferes with Zika and dengue virus replication by inhibition of the host signal peptidase. Cell Rep 2017 Apr 18:19(3):451-60

Fernandez E, Dejnirattisai W, Cao B, et al. Human antibodies to the dengue virus E-dimer epitope have therapeutic activity against Zika virus infection. Nat Immunol 2017 (published online Sep 25)

Ferreira AC, Zaverucha-do-Valle C, Reis PA, et al. Sofosbuvir protects Zika virus-infected mice from mortality, preventing short- and long-term sequelae. Sci Rep 2017 (published online Aug 25)

Ferreira MLB, de Brito CAA, Moreira AJP, et al. Guillain-Barre Syndrome, acute disseminated encephalomyelitis and encephalitis associated with Zika virus infection in Brazil: detection of viral RNA and isolation of virus during late infection. Am J Trop Med Hyg 2017 (published online Aug 28)

Hamel R, Ferraris P, Wichit S, et al. African and Asian Zika virus strains differentially induce early antiviral responses in primary human astrocytes. Infect Genet Evol 2017 (published online Jan 14)

Kazmirchuk T, Dick K, Burnside DJ, et al. Designing anti-Zika virus peptides derived from predicted human-Zika virus protein-protein interactions. bioRxiv 2017 Jun 29

Li C, Deng YQ, Wang S, et al. 25-hydroxycholesterol protects host against Zika virus infection and its associated microcephaly in a mouse model. Immunity 2017 (published online Mar 14)

Li C, Zhu X, Quanquin N, et al. Chloroquine, a FDA-approved drug, prevents ZIKV infection and its associated congenital microcephaly in mice. EBioMedicine 2017 (published online Sep 28)

Magnani DM, Rogers TF, Beutler N, et al. Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques. Sci Transl Med 2017 (published online Oct 4)

Magnani DM, Silveira CGT, Rosen BC, et al. A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus.PLoS Negl Trop Dis 2017 Jun 12;11(6): e0005655

McArthur MA. Zika virus: recent advances towards the development of vaccines and therapeutics. Viruses 2017 (published online Jun 13)

Meertens L, Labeau A, Dejarnac O, et al. Axl mediates Zika virus entry in human glial cells and modulates innate immune responses. Cell Rep 2017 Jan 10;18(2):324-33

Metz SW, Gallichotte EN, Brackbill A, et al. In vitro assembly and stabilization of dengue and Zika virus envelope protein Homo-Dimers. Sci Rep 2017 (published online Jul 3)

Mounce BC, Cesaro T, Carrau L, et al. Curcumin inhibits Zika and chikungunya virus infection by inhibiting cell binding. Antiviral Res 2017 (published online Mar 24)

Mumtaz N, Jimmerson LC, Bushman LR, et al. Cell-line dependent antiviral activity of sofosbuvir against Zika virus. Antiviral Res 2017 (published online Sep 11)

Rausch K, Hackett BA, Weinbren NL, et al. Screening bioactives reveals nanchangmycin as a braod spectrum antiviral active against ZIka virus. Cell Rep 2017 Jan 17;18(3):804-15

Robbiani DF, Bozzacco L, Keeffe JR, et al. Recurrent potent human neutralizing antibodies to Zika virus in Brazil and Mexico. Cell 2017 (published online May 4)

Sacramento CQ, de Melo GR, de Freitas CS, et al. The clinically approved antiviral drug sofosbuvir inhibits Zika virus replication. Sci Rep 2017 (published online Jan 18)

Salam AP, Rojek A, Dunning J, et al. Clinical trials of therapeutics for the prevention of congenital Zika virus disease: challenges and potential solutions. Ann Intern Med 2017 (published online Mar 21)

Saiz JC, Martín-Acebes MA. The race to find antivirals for Zika virus. Antimicrob Agents Chemother 2017 (published online Mar 27)

Shiryaev SA, Mesci P, Pinto A, et al. Repurposing of the anti-malaria drug chloroquine for Zika Virus treatment and prophylaxis. Sci Rep 2017 (published online Nov 17)

Siddharta A, Pfaender S, Vielle NJ, et al. Virucidal activity of WHO-recommended formulations against enveloped viruses including Zika, Ebola and emerging coronaviruses. J Infect Dis 2017 (published online Feb 1)

Stein DR, Golden JW, Griffin BD, et al. Human polyclonal antibodies produced in transchromosomal cattle prevent lethal Zika virus infection and testicular atrophy in mice. Antiviral Res 2017 (published online Sep 8)

Smith DR, Hollidge B, Daye S, et al. Neuropathogenesis of Zika virus in a highly susceptible immunocompetent mouse model after antibody blockade of type I interferon. PLoS Negl Trop Dis 2017 Jan 9;11(1):e0005296

Wang J, Bardelli M, Espinosa DA, et al. A human bi-specific antibody against Zika virus with high therapeutic potential. Cell 2017 (published online Sep 21)

Wen J, Tang WW, Sheets N, et al. Identification of Zika virus epitopes reveals immunodominant and protective roles for dengue virus cross-reactive CD8+T cells. Nat Microbiol 2017 (published online Mar 13)

Yu Y, Deng YQ, Zou P, et al. A peptide-based viral inactivator inhibits Zika virus infection in pregnant mice and fetuses. Nat Commun 2017 (published online Jul 25)

Watanabe M, Jessie E. Buth JE, Vishlaghi N, et al. Self-organized cerebral organoids with human-specific features predict effective drugs to combat Zika virus infection. Cell Rep 2017 (published online Oct 10)

Blood Supply

Chevalier MS, Biggerstaff BJ, Basavaraju SV, et al. Use of blood donor screening data to estimate Zika virus incidence, Puerto Rico, April-August 2016. Emerg Infect Dis 2017 (published online Mar 6)

Galel SA, Williamson PC, Busch MP, et al. First Zika-positive donations in the continental United States. Transfusion 2017 (published online Feb 5)

Gake B, Vernet MA, Leparc-Goffart I, et al. Low seroprevalence of Zika virus in Cameroonian blood donors. Braz J Infect Dis 2017 (published online May 23)

Lum FM, Lin C, Susova OY, et al. Sensitive detection of Zika virus antigen in patients' whole blood as an alternative diagnostic approach. J Infect Dis 2017 (published online Jun 6)

Mansuy JM, Mengelle C, Pasquier C, et al. Zika virus infection and prolonged viremia in whole-blood specimens. Emerg Infect Dis 2017 (published online Mar 3)

Rossini G, Gaibani P, Vocale C, et al. Comparison of Zika virus (ZIKV) RNA detection in plasma, whole blood and urine — case series of travel-associated ZIKV infection imported to Italy, 2016. J Infect 2017 (published online Jun 22)

Williamson PC, Linnen JM, Kessler DA, et al. First cases of Zika virus–infected US blood donors outside states with areas of active transmission. Transfusion 2017 (published online Feb 23)

Case Definitions

Braga JU, Bressan C, Dalvi APR, et al. Accuracy of Zika virus disease case definition during simultaneous dengue and chikungunya epidemics. PLoS One 2017 Jun 26;12(6):e0179725

Chow A, Ho H, Win MK, et al. Assessing sensitivity and specificity of surveillance case definitions for Zika virus disease. Emerg Infect Dis 2017 (published online Jan 24)

DeSilva M, Munoz FM, Sell E, et al. Congenital microcephaly: case definition & guidelines for data collection, analysis, and presentation of safety data after maternal immunisation. (Commentary) Vaccine 2017 (published online Nov 14)

Congenital Zika Syndrome/Fetal Infection



Acosta-Reyes J, Navarro E, Herrera MJ, et al. Severe neurologic disorders in 2 fetuses with Zika virus infection, Colombia. Emerg Infect Dis 2017 (published online Mar 15)

Adebanjo T, Godfred-Cato S, Viens L, et al. Update: Interim guidance for the diagnosis, evaluation, and management of infants with possible congenital Zika virus infection — United States, October 2017. MMWR 2017 Oct 20:66(41);1089-99

Adhikari EH, Nelson DB, Johnson KA, et al.Infant outcomes among women with ZIka virus infection during pregnancy: results of a large prenatal Zika screening program. Am J Obstet Gynecol 2017 (published online Jan 30)

Awadh A, Chughtai AA, Dyda A, et al. Does Zika virus cause microcephaly — applying the Bradford Hill viewpoints. PLoS Curr 2017 Feb 22

Bautista LE. Maternal Zika virus infection and newborn microcephaly—an analysis of the epidemiological evidence. Ann Epidemiol 2017 (published online Dec 13)

Benjamin I, Fernandez G, Figueira JV, et al. Zika virus detected in amniotic fluid and umbilical cord blood in an in vitro fertilization-conceived pregnancy in Venezuela. Fertil Steril 2017 (published online Apr 6)

Besnard M, Dub T, Geradin P. Outcomes for 2 children after peripartum acquisition of Zika virus infection, French Polynesia, 2013-2014. Emerg Infect Dis 2017 (published online May 9)

Chavali PL, Stojic L, Meredith LW, et al. Neurodevelopmental protein Musashi 1 interacts with the Zika genome and promotes viral replication. Science 2017 (published online Jun 1)

Chibueze EC, Parsons AJQ, da Silva Lopes K, et al. Diagnostic accuracy of ultrasound scanning for prenatal microcephaly in the context of Zika virus infection: a systematic review and meta-analysis. Sci Rep 2017 (published online May 23)

Coelho AVC, Crovella S. Microcephaly prevalence in infants born to Zika virus-infected women: a systematic review and meta-analysis. Int J Mol Sci 2017 (published online Aug 5)

Coelho FC, Armstrong M, Saraceni V, et al. Can Zika account for the missing babies? bioRxiv 2017 Apr 12

Cragan JD, Mai CT, Petersen EE, et al. Baseline prevalence of birth defects associated with congenital Zika virus infection — Massachusetts, North Carolina, and Atlanta, Georgia, 2013-2014. MMWR 2017 Mar 3;66(8):219-22

Cunha AJLA, de Magalhaes-Barbosa MC, Lima-Setta F, et al. Microcephaly case fatality rate associated with Zika virus infection in Brazil: current estimates. Pediatr Infect Dis J 2017 May;36(5):528-30

de Araujo TVB, de Alencar Ximenes RA, de Barros Miranda-Filho D, et al. Association between microcephaly, Zika virus infection, and other risk factors in Brazil: final report of a case-control study. Lancet Infect Dis 2017 (published online Dec 11)

del Campo M, Feitosa IML, Ribeiro EM, et al. The phenotypic spectrum of congenital Zika syndrome. Am J Med Genet 2017 Apr;173(4):841-57

de Lima Petribu NC, de Fatima Vasco Aragao M, van der Linden V, et al. Follow-up brain imaging of 37 children with congenital Zika syndrome: case series study. BMJ 2017 (published online Oct 13)

de Olveira WK, de Franca GVA, Carmo EH, et al. Infection-related microcephaly after the 2015 and 2016 Zika virus outbreaks in Brazil: a surveillance-based analysis. Lancet 2017 (published online Jun 21)

Dreier JW, Strandberg-Larsen K, Uldall PV, et al. Fever in pregnancy and offspring head circumference. Ann Epidemiol 2017 (published online Dec 6)

DeSilva M, Munoz FM, Sell E, et al. Congenital microcephaly: case definition & guidelines for data collection, analysis, and presentation of safety data after maternal immunisation. (Commentary) Vaccine 2017 (published online Nov 14)

Eggo RM, Kucharski AJ. Expected duration of adverse pregnancy outcomes after Zika epidemic. Emerg Infect Dis 2017 (published online Oct 23)

Fernandez MP, Saad EP, Martinez MO, et al. Ocular histopathologic features of congenital Zika syndrome. JAMA Ophthalmol 2017 (published online Sep 21)

Graham KA, Fox DJ, Talati A, et al. Prevalence and clinical attributes of congenital microcephaly — New York, 2013-2015. MMWR 2017 Feb 10;66(5):125-9

Halai UA, Nielsen-Saines K, Moreira ME, et al. Maternal Zika virus disease severity, virus load, prior dengue antibodies and their relationship to birth outcomes. Clin Infect Dis 2017 (published online May 23)

Hall NB, Broussard K, Evert N, et al. Zika virus-associated neonatal birth defects surveillance — Texas, January 2016-July 2017. (Notes from the field) MMWR 2017 Aug 11;66(31):835-6

Hoyt AT, Canfield MA, Langlois PH, et al. Pre-Zika descriptive epidemiology of microcephaly in Texas, 2008–2012. Birth Defects Res 2017 (published online Nov 24)

Hurtado-Villa P, Puerto AK, Victoria S, et al. Raised frequency of central nervous system malformations related to Zika virus infection in two birth defects surveillance systems in Bogota and Cali, Colombia. Pediatr Infect Dis J 2017 (published online Jul 1)

Kapogiannis BG, Chakhtoura N, Hazra R, et al. Bridging knowledge gaps to understand how Zika virus exposure and infection affect child development. JAMA Pediatr 2017 (published online Feb 20)

Krauer F, Riesen M, Reveiz L, et al. Zika virus infection as a cause of congenital brain abnormalities and Guillain-Barre syndrome: systematic review. PLoS Med 2017 Jan 3;14(1):e1002203

Lum FM, Low DKS, Fan Y, et al. Zika virus infects human fetal brain microglia and induces inflammation. Clin Infect Dis 2017 (published online Feb 21)

Mattar S, Ojeda C, Arboleda J, et al. Case report: microcephaly associated with Zika virus infection, Colombia. BMC Infect Dis 2017 (published online Jun 13)

McGrath EL, Rossi SL, Gao J, et al. Differential responses of human fetal brain neural stem cell to Zika virus infection. Stem Cell Rep 2017 (published online Feb 16)

Mejdoubi M, Monthieux A, Cassan T, et al. Brain MRI in infants after maternal Zika virus infection during pregnancy. (Letter) N Engl J Med 2017 (published online Oct 4)

Merfeld E, Ben-Avi L, Kennon M, et al. Potential mechanisms of Zika-linked microcephaly. Dev Biol 2017 (published online Apr 6)

Mohr EL, Block LN, Newman CM, et al. Ocular and uteroplacental pathology in macaque congenital Zika virus infection. bioRxiv 2017 Sep 30

Moreira-Soto A, Sarno M, Pedroso C, et al. Evidence for congenital Zika virus infection from neutralizing antibody titers in maternal sera, north-eastern Brazil. J Infect Dis 2017 (published online Oct 9)

Nogueira ML, Junior NRRN, Estofolete CF, et al. Adverse birth outcomes associated with Zika virus exposure during pregnancy in Sao Jose do Rio Preto, Brazil. Clin Microbiol Infect 2017 (published online Nov 10)

Orioli IM, Dolk H, Lopez-Camelo JS, et al. Prevalence and clinical profile of microcephaly in South America pre-Zika, 2005-14: prevalence and case-control study. BMJ 2017 Nov 21;359:j5018

Parens R, Bar-Yam Y, Morales A, et al. A possible link between pyriproxyfen and microcephaly. PLoS Curr 2017 Nov 27

Rasmussen SA, Meaney-Delman DM, Petersen LR, et al. Studying the effects of emerging infections on the fetus: experience with West Nile and Zika viruses. Birth Defects Res 2017 Mar 15;109(5):363-71

Reagan-Steiner S, Simeone R, Simon E, et al. Evaluation of placental and fetal tissue specimens for Zika virus infection — 50 states and District of Columbia, January-December, 2016. MMWR 2017 Jun 23;66(24):636-43

Reynolds MR, Jones AM, Petersen EE, et al. Update on Zika virus-associated birth defects and evaluation of all U.S. infants with congenital Zika virus exposure — U.S. Zika Pregnancy Registry, 2016. (Vital signs) MMWR 2017 Apr 4;66(Early release)

Santos VS, Oliveira SJG, Gurgel RQ, et al. Microcephaly in twins due to the Zika virus. Am J Trop Med Hyg 2017 (published online Apr 10)

Satterfield-Nash A, Kotzky K, Allen J, et al. Health and development at age 19-24 months of 19 children who were born with microcephaly and laboratory evidence of congenital Zika virus infection during the 2015 Zika virus outbreak — Brazil, 2017. MMWR 2017 Dec 15;66(49):1347-51

Schaub B, Vouga M, Najioullah F, et al. Analysis of blood from Zika virus-infected fetuses: a prospective case series. Lancet Infect Dis 2017 (published online Feb 10)

Shapiro-Mendoza CK, Rice ME, Galang RR, et al. Pregnancy outcomes after maternal Zika virus infection during pregnancy — U.S. territories, January 1, 2016-April 25, 2017. MMWR 2017 Jun 8;66(Early release)

Sheridan MA, Yunusov D, Balaraman V, et al. Vulnerability of primitive human placental trophoblast to Zika virus. Proc Natl Acad Sci USA 2017 (published online Feb 13)

Shiu C, Starker R, Kwal J, et al. Zika virus testing and outcomes during pregnancy, Florida, USA, 2016. Emerg Infect Dis 2017 (published online Dec 18)

Sousa AQ, Cavalcante DIM, Franco LM, et al. Postmortem findings for 7 neonates with congenital Zika virus infection. Emerg Infect Dis 2017 (published online May 1)

Tabata T, Petitt M, Puerta-Guardo H, et al. Zika virus replicates in proliferating cells in explants from first-trimester human placentas, potential sites for dissemination of infection. J Infect Dis 2017 (published online Nov 2)

Turner LH, Kinder JM, Adrienne Wilburn A, et al. Preconceptual Zika virus asymptomatic infection protects against secondary prenatal infection. PLoS Pathog 2017 Nov 16;13(11):e1006684

Vermillion MS, Lei J, Shabi Y, et al. Intrauterine Zika virus infection of pregnant immunocompetent mice models transplacental transmission and adverse perinatal outcomes. Nat Commun 2017 (published online Feb 21)

Wang D, Chen C, Liu S, et al. A mutation identified in neonatal microcephaly destabilizes Zika virus NS1 assembly in vitro. Sci Rep 2017 (published online Feb 15)

Weaver SC. Emergence of epidemic Zika virus transmission and congenital Zika syndrome: are recently evolved traits to blame? mBio 2017 Jan 10;8(1):e02063-16

Yuan L, Huang XY, Liu ZY, et al. A single mutation in the prM protein of Zika virus contributes to fetal microcephaly. Science 2017 (published online Sep 28)

Zacharias N, Whitty J, Noblin S, et al. First neonatal demise with travel-associated Zika virus infection in the United States of America. AJP Rep 2017 Apr;7(2):e68-73

Zin AA, Tsui I, Rossetto J, et al. Screening criteria for ophthalmic manifestations of congenital Zika virus infection. JAMA Pediatr 2017 (published online Jul 17)

Zorrilla CD, Garcia IG, Fragoso LG, et al. Zika virus infection in pregnancy: maternal, fetal, and neonatal considerations. J Infect Dis 2017 (published online Dec 16)

Cutaneous Symptoms

Chen L, Hafeez F, Curry CL, et al. Cutaneous eruption in a U.S woman with locally acquired Zika virus infection. (Letter) N Engl J Med 2017 (published online Jan 11)

Diagnostics

Balmaseda A, Stettler K, Medialdea-Carrera R, et al. Antibody-based assay discriminates Zika virus infection from other flaviviruses. PNAS 2017 (published online Jul 17)

Bosch I, de Puig H, Hiley M, et al. Rapid antigen tests for dengue virus serotypes and Zika virus in patient serum. Sci Transl Med 2017 (published online Sep 27)

Calvert AE, Biggerstaff BJ, Tanner NA, et al. Rapid colorimetric detection of Zika virus from serum and urine specimens by reverse transcription loop-mediated isothermal amplification (RT-LAMP). PLoS One 2017 Sep 25;12(9):e0185340

Carossino M, Li Y, Lee PYA, et al. Evaluation of a field-deployable reverse transcription-insulated isothermal PCR for rapid and sensitive on-site detection of Zika virus. BMC Infect Dis 2017 (published online Dec 19)

Chibueze EC, Parsons AJQ, da Silva Lopes K, et al. Diagnostic accuracy of ultrasound scanning for prenatal microcephaly in the context of Zika virus infection: a systematic review and meta-analysis. Sci Rep 2017 (published online May 23)

Chua A, Prat I, Nuebling CM, et al. Update on Zika diagnostic tests and WHO’s related activities. PLoS Negl Trop Dis 2017 Feb 2;11(2):e0005269

Eppes C, Rac M, Dunn J, et al. Testing for Zika virus (ZIKV) infection in pregnancy: key concepts to deal with an emerging epidemic. Am J Obstet Gynecol 2017 (published online Jan 23)

Felix AC, Souza NCS, Figueiredo WM, et al. Cross reactivity of commercial anti-dengue immunoassays in patients with acute Zika virus infection. J Med Virol 2017 (published online Mar 3)

Goldfarb IT, Jaffe E, Lyerly AD. Responsible care in the face of shifting recommendations and imperfect diagnostics for Zika virus. JAMA 2017 (published online Oct 27)

Hancock WT, Soeters HM, Hills SL, et al. Establishing a timeline to discontinue routine testing of asymptomatic pregnant women for Zika virus infection — American Samoa, 2016-2017. MMWR 2017 Mar 24;66(11):299-301

Ho HJ, Wong JGX, Kyaw WM, et al. Diagnostic accuracy of parameters for Zika and dengue virus infections, Singapore. Emerg Infect Dis 2017 (published online Nov 2)

Jiang Q, Chandar YJ, Cao S, et al. Rapid, point-of-care, paper-based plasmonic biosensor for Zika virus diagnosis. Adv Biosyst 2017 (published online Aug 10)

Lee AJ, Bhattacharya R, Scheuermann RH, et al. Identification of diagnostic peptide regions that distinguish Zika virus from related mosquito-borne Flaviviruses. PLoS One 2017 May 31;12(5):e0178199.

L'Huillier AG, Hamid-Allie A, Kristjanson E, et al. Evaluation of Euroimmun anti-Zika virus ELISAs (IgM & IgG) for Zika virus serologic testing. J Clin Microbiol 2017 (published online May 31)

Munoz-Jordan JL. Diagnosis of Zika virus infections: challenges and opportunities. J Infect Dis 2017 (published online Dec 16)

Lum FM, Lin C, Susova OY, et al. Sensitive detection of Zika virus antigen in patients' whole blood as an alternative diagnostic approach. J Infect Dis 2017 (published online Jun 6)

Oduyebo T, Polen KD, Walke HT, et al. Interim guidance for health care providers caring for pregnant women with possible Zika virus exposure — United States (including U.S. territories), July 2017. (Update) MMWR 2017 Jul 24;66(Early online)

Olschlager S, Enfissi A, Zaruba M, et al. Diagnostic validation of the RealStar Zika virus reverse transcription polymerase chain reaction kit for detection of Zika virus RNA in urine and serum specimens. Am J Trop Med Hyg 2017 Oct;97(4):1070-1

Priye A, Bird SW, Light YK, et al. A smartphone-based diagnostic platform for rapid detection of Zika, chikungunya, and dengue viruses. Sci Rep 2017 (published online Mar 20)

Safronetz D, Sloan A, Stein DR, et al. Evaluation of 5 commercially available Zika virus immunoassays. Emerg Infect Dis 2017 (published online Aug 17)

Tsai WY, Youn HH, Brites C, et al. Distinguishing secondary dengue virus infection from Zika virus infection with previous dengue by a combination of three simple serological tests. Clin Infect Dis 2017 (published online Jul 29)

Wahed AAE, Sanabani SS, Faye O, et al. Rapid molecular detection of Zika virus in acute-phase urine samples using the recombinase polymerase amplification assay. PLoS Curr 2017 Jan 25

Wilson HL, Tran T, Druce J, et al. A neutralization assay for Zika and Dengue viruses using a real-time PCR-based endpoint assessment. J Clin Microbiol 2017 (published online Aug 9)

Zhang B, Pinsky BA, Ananta JS, et al. Diagnosis of Zika virus infection on a nanotechnology platform. Nat Med 2017 (published online Mar 6)

Zuanazzi D, Arts EJ, Jorge PK, et al. Postnatal identification of Zika virus peptides from saliva. J Dent Res 2017 (published online Aug 21)

Economic Burden

Lee BY, Alfaro-Murillo JA, Parpia AS, et al. The potential economic burden of Zika in the continental United States. PLoS Negl Trop Dis 2017 Apr 27;11(4):e0005531

Epidemiology

Ali S, Gugliemini O, Harber S, et al. Environmental and social change drive the explosive emergence of Zika virus in the Americas. PLoS Negl Trop Dis 2017 Feb 9;11(2):e0005135

Bautista LE. Maternal Zika virus infection and newborn microcephaly—an analysis of the epidemiological evidence. Ann Epidemiol 2017 (published online Dec 13)

Boggild AK, Geduld J, Libman M, et al. Surveillance report of Zika virus among Canadian travelers returning from the Americas. CMAJ 2017 Mar 6;189(9):E334-40

Faria NR, Quick J, Morales I, et al. Epidemic establishment and cryptic transmission of Zika virus in Brazil and the Americas. bioRxiv 2017 Mar 27

Ferreira MLB, de Brito CAA, Moreira AJP, et al. Guillain-Barre Syndrome, acute disseminated encephalomyelitis and encephalitis associated with Zika virus infection in Brazil: detection of viral RNA and isolation of virus during late infection. Am J Trop Med Hyg 2017 (published online Aug 28)

Griffin I, Zhang G, Fernandez D, et al. Epidemiology of pediatric Zika virus infections. Pediatrics 2017 (published online Nov 1)

Grubaugh ND, Ladner JT, Kraemer MUG, et al. Genomic epidemiology reveals multiple introductions of Zika virus into the United States. (Letter) Nature 2017 (published online May 24)

Hills SL, Fischer M, Petersen LR. Epidemiology of Zika virus infection. J Infect Dis 2017 (published online Dec 16)

Herrera BB, Chang CA, Hamel DJ, et al. Continued transmission of Zika virus in humans in West Africa, 1992-2016. J Infect Dis 2017 (published online Apr 8)

Ho ZJM, Hapuarachchl HC, Barkham T, et al. Outbreak of Zika virus infection in Singapore: an epidemiological, entomological, virological, and clinical analysis. Lancet Infect Dis 2017 (published online May 17)

Lourenco J, de Lourdes Monteiro M, Valdez T, et al. Zika virus outbreak in Cabo Verde Islands, West Africa: early epidemiological findings. bioRxiv 2017 Oct 6

Lozier MJ, Burke RM, Lopez J, et al. Differences in prevalence of symptomatic Zika virus infection by age and sex — Puerto Rico, 2016. J Infect Dis 2017 (published online Dec 6)

Massad E, Burattini MN, Khan K, et al. On the origin and timing of Zika virus introduction in Brazil. Epidemiol Infect 2017 (published online Jun 15)

Osorio-de-Castro CGS, Miranda ES, Machado de Freitas C, et al. The Zika virus outbreak in Brazil: knowledge gaps and challenges for risk reduction. Am J Public Health 2017 (published online Apr 20)

Reagan-Steiner S, Simeone R, Simon E, et al. Evaluation of placental and fetal tissue specimens for Zika virus infection — 50 states and District of Columbia, January-December, 2016. MMWR 2017 Jun 23;66(24):636-43

Rodriguez-Morales AJ, Ruiz P, Tabares J, et al. Mapping the ecoepidemiology of Zika virus infection in urban and rural areas of Pereira, Risaralda, Colombia, 2015-2016: implications for public health and travel medicine. Travel Med Infect Dis 2017 (published online May 6)

Sapkal GN, Yadav PD, Vegad MM, et al. First laboratory confirmation on the existence of Zika virus disease in India. J Infect 2017 (published online Oct 6)

Spiteri G, Sudre B, Septfons A. Surveillance of Zika virus infection in the EU/EEA, June 2015 to January 2017. Euro Surveill 2017 Oct 12;22(41):pii=17-00254

Wong N, Ahmed A, Ahmed O, et al. A series of Zika virus cases imported into the UK 2016: comparative epidemiological and clinical features. J Infect 2017 (published online Mar 23)

Zhang Q, Sun K, Chinazzi M, et al. Spread of Zika virus in the Americas. Proc Natl Acad Sci USA 2017 (published online Apr 25)

Genetic Characteristics

Black A, Potter B, Dudas G, et al. Genetic characterization of the Zika virus epidemic in the US Virgin Islands. bioRxiv 2017 Mar 3

Blohm GM, Lednicky JA, Marquez M, et al. Complete genome sequences of identical Zika virus isolates in a nursing mother and her infant. Genome Announc 2017 (published online Apr 27)

Faria NR, Quick J, Claro IM, et al. Establishment and cryptic transmission of Zika virus in Brazil and the Americas. (Letter) Nature 2017 (published online May 24)

Garcez PP, Nascimento JM, de Vasconcelos JM, et al. Zika virus disrupts molecular fingerprinting of human neurospheres. Sci Rep 2017 (published online Jan 23)

Garg H, Sedano M, Plata G, et al. Development of virus like particle vaccine and reporter assay for Zika virus. J Virol 2017 (published online Aug 9)

Grubaugh ND, Ladner JT, Kraemer MUG, et al. Genomic epidemiology reveals multiple introductions of Zika virus into the United States. (Letter) Nature 2017 (published online May 24)

Gu SH, Song DH, Lee D, et al. Whole-genome sequence analysis of Zika virus, amplified from urine of traveler from the Philippines.Virus Genes 2017 (published online Aug 9)

Li G, Poulsen M, Fenyvuesvolgyi C, et al. Characterization of cytopathic factors through genome-wide analysis of the Zika viral proteins in fission yeast. Proc Natl Acad Sci USA 2017 (published online Jan 3)

Metsky HC, Matranga CB, Wohl S, et al. Zika virus evolution and spread in the Americas. (Letter) Nature 2017 (published online May 24)

Moni MA, Lio P. Genetic profiling and comorbidities of Zika infection. J Infect Dis 2017 (published online Jul 27)

Setoh YX, Prow NA, Peng N, et al. De novo generation and characterization of new Zika virus isolate using sequence data from a microcephaly case. mSphere 2017 (published online May 17)

Widman DG, Young E, Yount BL, et al. A reverse genetics platform that spans the Zika virus family tree. mBio 2017 Mar 7;8(2):e02014-16

Yudhaputri FA, Trimarsanto H, Perkasa A, et al. Genomic characterization of Zika virus isolated from Indonesia. Virology 2017 (published online Jul 26)

Insecticide Link



Parens R, Bar-Yam Y, Morales A, et al. A possible link between pyriproxyfen and microcephaly. PLoS Curr 2017 Nov 27

Literature Review

Albuquerque PC, Castro MJC, Santos-Gandelman J, et al. Bibliometric indicators of the Zika outbreak. PLoS Negl Trop Dis 2017 Jan 19;11(1): e0005132

Male Fertility Issues

de Laval F, Matheus S, Labrousse T, et al. Kinetics of Zika viral load in semen. (Letter to the editor) N Engl J Med 2017 (published online Aug 17)

Joguet G, Mansuy JM, Matusali G, et al. Effect of acute Zika virus infection on sperm and virus clearance in body fluids: a prospective observational study. Lancet Infect Dis 2017 (published online Aug 21)

Shan C, Muruato AE, Jagger BW, et al. A single-dose live-attenuated vaccine prevents Zika virus pregnancy transmission and testis damage. Nat Commun 2017 (published online Sep 22)

Uraki R, Hwang J, Jurado KA, et al. Zika virus causes testicular atrophy. Sci Adv 2017 Feb 22;3(2):e1602899

Musculoskeletal Sequelae

Molko N, Simon O, Guyon D, et al. Zika virus infection and myasthenia gravis: report of 2 cases. Neurology 2017 (published online Feb 10)

Neurologic Manifestations

Aid M, Abbink P, Larocca RA, et al. Zika virus persistence in the central nervous system and lymph nodes of rhesus monkeys. Cell 2017 (published online Apr 27)

Anaya JM, Rodriguez Y, Monsalve DM, et al. A comprehensive analysis and immunobiology of autoimmune neurological syndromes during the Zika virus outbreak in Cucuta, Colombia. J Autoimmun 2017 (published online Jan 3)

Brito CAA, Azevedo F, Cordeiro MT, et al. Central and peripheral nervous system involvement caused by Zika and chikungunya coinfection. PLoS Negl Trop Dis 2017 Jul 13;11(7):e0005583

Chavali PL, Stojic L, Meredith LW, et al. Neurodevelopmental protein Musashi 1 interacts with the Zika genome and promotes viral replication. Science 2017 (published online Jun 1)

Costa VV, Del Sarto JL, Rocha RF, et al. N-methyl-d-aspartate (NMDA) receptor blockade prevents neuronal death induced by Zika virus infection. mBio 2017 Apr 25;8(2):e00350-17

Coelho AVC, Crovella S. Microcephaly prevalence in infants born to Zika virus-infected women: a systematic review and meta-analysis. Int J Mol Sci 2017 (published online Aug 5)

Cui L, Zou P, Chen E, et al. Visual and motor deficits in grown-up mice with congenital Zika virus infection. eBioMedicine 2017 (published online Apr 24)

da Silva IRF, Frontera JA, de Filippis AMB, et al. Neurologic complications associated with the Zika virus in Brazilian adults. JAMA Neurol 2017 (published online Aug 14)

de Lima Petribu NC, de Fatima Vasco Aragao M, van der Linden V, et al. Follow-up brain imaging of 37 children with congenital Zika syndrome: case series study. BMJ 2017 (published online Oct 13)

Dirlikov E, Torres JV, Martines RB, et al. Postmortem findings in patient with Guillain-Barre syndrome and Zika virus infection. Emerg Infect Dis 2017 (published online Dec 19)

Dirlikov E, Medina NA, Major CG, et al. Acute Zika virus infection as a risk factor for Guillain-Barre syndrome in Puerto Rico. (Letter) JAMA 2017 Oct 17;318(15):1498-1500

Gabriel E, Ramani A, Karow U, et al. Recent Zika virus isolates induce premature differentiation of neural progenitors in human brain organoids. Cell Stem Cell 2017 (published online Jan 26)

Hurtado-Villa P, Puerto AK, Victoria S, et al. Raised frequency of central nervous system malformations related to Zika virus infection in two birth defects surveillance systems in Bogota and Cali, Colombia. Pediatr Infect Dis J 2017 (published online Jul 1)

Jurado KA, Yockey LJ, Wong PW, et al. Antiviral CD8 T cells induce Zika-virus-associated paralysis in mice. Nat Microbiol 2017 (published online Nov 20)

Kam YW, Leite JA, Lum FM, et al. Specific biomarkers associated with neurological complications and congenital CNS abnormalities from Zika virus-infected patients in Brazil. J Infect Dis 2017 (published online May 30)

Krauer F, Riesen M, Reveiz L, et al. Zika virus infection as a cause of congenital brain abnormalities and Guillain-Barre syndrome: systematic review. PLoS Med 2017 Jan 3;14(1):e1002203

Landais A, Audrey Cesaire A, Fernandez M, et al. Zika vasculitis: a new cause of stroke in children? (Letter) J Neurol Sci 2017 (published online Oct 27)

Mejdoubi M, Monthieux A, Cassan T, et al. Brain MRI in infants after maternal Zika virus infection during pregnancy. (Letter) N Engl J Med 2017 (published online Oct 4)

Munoz LS, Parra B, Pardo CA. Neurological implications of Zika virus infection in adults. J Infect Dis 2017 (published online Dec 16)

Oh Y, Zhang F, Wang Y, et al. Zika virus directly infects peripheral neurons and induces cell death. Nat Neurosci 2017 (published online Jul 31)

Ramalho FS, Yamamoto AY, da Silva LL, et al. Congenital Zika virus infection induces severe spinal cord injury. Clin Infect Dis 2017 (published online Apr 21)

Rosenfeld AB, Doobin DJ, Warren AL, et al. Replication of early and recent Zika virus isolates throughout mouse brain development. Proc Natl Acad Sci USA 2017 (published online Oct 31)

Roze B, Najioullah F, Ferge JL, et al. Guillain-Barre syndrome associated with Zika virus infection in Martinique in 2016: a prospective study. Clin Infect Dis 2017 (published online Jul 20)

Salinas JL, Major CG, Pastula DM, et al. Incidence and clinical characteristics of Guillain-Barre syndrome before the introduction of Zika virus in Puerto Rico. J Neurol Sci 2017 (published online Apr 7)

Salinas JL, Walteros DM, Styczynski A, et al. Zika virus disease-associated Guillain-Barre syndrome — Barranquilla, Colombia 2015-2016. J Neurol Sci 2017 (published online Sep 4)

Schwartzmann PV, Ramalho LNZ, Neder L, et al. Zika virus meningoencephalitis in an immunocompromised patient. Mayo Clin Proc 2017 Mar;92(3):460-6

Styczynski AR, Malta JMAS, Krow-Lucal ER, et al. Increased rates of Guillain-Barre syndrome associated with Zika virus outbreak in the Salvador metropolitan area, Brazil. PLoS Negl Trop Dis 2017 Aug 30;11(8):e0005869

Tsakiri S, Zacharias N, Garcia J, et al. Cranial asymmetry versus microcephaly: implications for practice during the Zika virus epidemic. Tex Med 2017 Aug 2;113(9):e1

van den Pol AN, Mao G, Yang Y, et al. Zika virus targeting in the developing brain. J Neurosci 2017 (published online Jan 25)

Yi L, Pimentel H, Pachter L. Zika infection of neural progenitor cells perturbs transcription in neurodevelopmental pathways. PLoS One 2017 Apr 27;12(4):e0175744

Yuan L, Huang XY, Liu ZY, et al. A single mutation in the prM protein of Zika virus contributes to fetal microcephaly. Science 2017 (published online Sep 28)

Non-Human Primate Infections

Abbink P, Larocca RA, Visitsunthorn K, et al. Durability and correlates of vaccine protection against Zika virus in rhesus monkeys. Sci Transl Med 2017 (published online Dec 13)

Aid M, Abbink P, Larocca RA, et al. Zika virus persistence in the central nervous system and lymph nodes of rhesus monkeys. Cell 2017 (published online Apr 27)

Best K, Guedj J, Madelain V, et al. Zika plasma viral dynamics in nonhuman primates provides insights into early infection and antiviral strategies. Proc Natl Acad Sci USA 2017 (published online Aug 1)

Carroll T, Lo M, Lanteri M, et al. Zika virus preferentially replicates in the female reproductive tract after vaginal inoculation of rhesus macaques.PLoS Pathog 2017 Jul 26;13(7):e1006537

Chiu CY, Bouquet J, Li T, et al. Experimental Zika virus infection in a new world monkey model reproduces key features of the human disease. bioRxiv 2017 Jan 21

Dudley DM, Newman CM, Lalli J, et al. Infection via mosquito bite alters Zika virus tissue tropism and replication kinetics in rhesus macaques. Nat Commun 2017 (published online Dec 13)

George J, Valiant WG, Mattapallil MJ, et al. Prior exposure to Zika virus significantly enhances peak dengue-2 viremia in rhesus macaques. Sci Rep 2017 (published online Sep 5)

Haddow AD, Nalca A, Rossi FD, et al. High infection rates for adult macaques after intravaginal or intrarectal inoculation with Zika virus. Emerg Infect Dis 2017 (published online May 26)

Hirsch AJ, Smith JL, Haese NN, et al. Zika Virus infection of rhesus macaques leads to viral persistence in multiple tissues. PLoS Pathog 2017 Mar 9;13(3):e1006219

Magnani DM, Rogers TF, Beutler N, et al. Neutralizing human monoclonal antibodies prevent Zika virus infection in macaques. Sci Transl Med 2017 (published online Oct 4)

McCracken MK, Gromowski GD, Friberg HL, et al. Impact of prior flavivirus immunity on Zika virus infection in rhesus macaques. PLoS Pathog 2017 Aug 3;13(8):e1006487

Newman C, Friedrich TC, O’Connor DH. Macaque monkeys in Zika virus research: 1947-present. Curr Opin Virol 2017 (published online Jul 24)

Newman CM, Dudley DM, Aliota MT, et al. Oropharyngeal mucosal transmission of Zika virus in rhesus macaques. Nat Commun 2017 (published online Aug 1)

Nguyen SM, Antony KM, Dudley DM, et al. Highly efficient maternal-fetal Zika virus transmission in pregnant rhesus macaques. bioRxiv 2017 May 11

Pantoja P, Perez-Guzman EX, Rodriguez IV, et al. Zika virus pathogenesis in rhesus macaques is unaffected by pre-existing immunity to dengue virus. Nat Commun 2017 (published online Jun 23)

Vanchiere JA, Ruiz JC, Brady AG, et al. Experimental Zika virus infection of neotropical primates. Am J Trop Med Hyg 2017 (published online Nov 27)

Non-Mosquito Vectors



Darbellay J, Lai K, Babiuk S, et al. Neonatal pigs are susceptible to experimental Zika virus infection. (Letter) Emerg Microb Infect 2017 (published online Feb 15)

Ragan IK, Blizzard EL, Gordy P, et al. Investigating the potential role of North American animals as hosts for Zika virus. Vector Borne Zoonotic Dis 2017 (published online Feb 1)

Ophthalmologic Manifestations

Aleman TS, Ventura CV, Cavalcanti MM, et al. Quantitative assessment of microstructural changes of the retina in infants with congenital Zika syndrome. JAMA Opthalmol 2017 (published online Sep 7)

Fernandez MP, Saad EP, Martinez MO, et al. Ocular histopathologic features of congenital Zika syndrome. JAMA Ophthalmol 2017 (published online Sep 21)

Mohr EL, Block LN, Newman CM, et al. Ocular and uteroplacental pathology in macaque congenital Zika virus infection. bioRxiv 2017 Sep 30

Tan JJL, Balne PK, Leo YS, et al. Persistence of Zika virus in conjunctival fluid of convalescence patients. Sci Rep 2017 (published online Sep 11)

Yepez JB, Murati FA, Pettito M, et al. Ophthalmic manifestations of congenital Zika syndrome in Colombia and Venezuela. JAMA Ophthamol 2017 (published online Apr 13)

Zin AA, Tsui I, Rossetto J, et al. Screening criteria for ophthalmic manifestations of congenital Zika virus infection. JAMA Pediatr 2017 (published online Jul 17)

Outbreak Dynamics, Control

Alaniz AJ, Bacigalupo A, Cattan PE. Spatial quantification of the world population potentially exposed to Zika virus. Int J Epidemiol 2017 (published online Feb 23)

Andronico A, Dorleans F, Ferge JL, et al. Real-time assessment of health-care requirements during the Zika virus epidemic in Martinique. Am J Epidemiol 2017 (published online Feb 15)

Brooks T, Roy-Burman A, Tuholske C, et al. Real-time evolution of Zika virus disease outbreak, Roatan, Honduras. Emerg Infect Dis 2017 (published online Apr 27)

Castro LA, Fox SJ, Chen X, et al. Assessing real-time Zika risk in the United States. bioRxiv 2017 Mar 22

Castro M, Perez D, Guzman MG, et al. Why did Zika not explode in Cuba? The role of active community participation to sustain control of vector-borne diseases. Am J Trop Med Hyg 2017 Aug;97(2):311-2

Faria NR, Quick J, Claro IM, et al. Establishment and cryptic transmission of Zika virus in Brazil and the Americas.(Letter) Nature 2017 (published online May 24)

GAO (US Government Accountability Office). Emerging infectious diseases: actions needed to address the challenges of responding to Zika virus disease outbreaks. GAO-17-445. May 23, 2017

He D, Gao D, Lou Y, et al. A comparison study of Zika virus outbreaks in French Polynesia, Colombia and the state of Bahia in Brazil. Sci Rep 2017 (published online Mar 21)

Ho ZJM, Hapuarachchl HC, Barkham T, et al. Outbreak of Zika virus infection in Singapore: an epidemiological, entomological, virological, and clinical analysis. Lancet Infect Dis 2017 (published online May 17)

Kroelinger CD, Romero L, Lathrop E, et al. State and local implementation strategies for increasing access to contraception during zika preparedness and response — United States, September 2016. (Meeting summary) MMWR 2017 Nov 10;66(44):1230-5

Lourenco J, de Lourdes Monteiro M, Valdez T, et al. Zika virus outbreak in Cabo Verde Islands, West Africa: early epidemiological findings. bioRxiv 2017 Oct 6

Marini G, Guzzetta G, Rosa R, et al. First outbreak of Zika virus in the continental United States: a modelling analysis. Euro Surveill 2017 Sep 14;22(37):pii=30612

Massad E, Burattini MN, Khan K, et al. On the origin and timing of Zika virus introduction in Brazil. Epidemiol Infect 2017 (published online Jun 15)

Metsky HC, Matranga CB, Wohl S, et al. Zika virus evolution and spread in the Americas. (Letter) Nature 2017 (published online May 24)

Mordecai EA, Cohen JM, Evans MV, et al. Detecting the impact of temperature on transmission of Zika, dengue, and chikungunya using mechanistic models. PLoS Negl Trop Dis 2017 Apr 27;11(4):e0005568

Musso D, Bossin H, Mallet HP, et al. Zika virus in French Polynesia 2013-14: anatomy of a completed outbreak. Lancet Infect Dis 2017 (published online Nov 14)

Osorio-de-Castro CGS, Miranda ES, Machado de Freitas C, et al. The Zika virus outbreak in Brazil: knowledge gaps and challenges for risk reduction. Am J Public Health 2017 (published online Apr 20)

Pompon J, Morales-Vargas R, Manuel M, et al. A Zika virus from America is more efficiently transmitted than an Asian virus by Aedes aegypti mosquitoes from Asia. Sci Rep 2017 (published online Apr 27)

Ryan SJ, Carlson CJ, Stewart-Ibarra AM, et al. Outbreak of Zika virus infections, Dominica, 2016. Emerg Infect Dis 2017 (published online Oct 11)

Shacham E, Nelson EJ, Hoft DF, et al. Potential high-risk areas for

Zika virus transmission in the contiguous United States. Am J Public Health 2017 (published online Mar 21)

Teng Y, Bi D, Xie G, et al. Dynamic forecasting of Zika epidemics using Google Trends. PLoS One 2017 Jan 6;12(1):e0165085

Zhang Q, Sun K, Chinazzi M, et al. Spread of Zika virus in the Americas. Proc Natl Acad Sci USA 2017 (published online Apr 25)

Pregnancy

Adhikari EH, Nelson DB, Johnson KA, et al.Infant outcomes among women with ZIka virus infection during pregnancy: results of a large prenatal Zika screening program. Am J Obstet Gynecol 2017 (published online Jan 30)

Blohm GM