(Just Kidding, it’s 144)

By Nancy Appleton PhD & G.N. Jacobs

Excerpted from Suicide by Sugar

Used with permission

updated 2015

Sugar can suppress your immune system. Sugar upsets the mineral relationships in the body. Sugar can cause juvenile delinquency in children. Sugar eaten during pregnancy and lactation can influence muscle force production in offspring, which can affect an individual’s ability to exercise. Sugar in soda, when consumed by children, results in the children drinking less milk. Sugar can elevate glucose and insulin responses and return them to fasting levels slower in oral contraceptive users. Sugar can increase reactive oxygen species (ROS), which can damage cells and tissues. Sugar can cause hyperactivity, anxiety, inability to concentrate and crankiness in children. Sugar can produce a significant rise in triglycerides.

10. Sugar reduces the body’s ability to defend against bacterial infection.

11. Sugar causes a decline in tissue elasticity and function – the more sugar you eat, the more elasticity and function you lose.

12. Sugar reduces high-density lipoproteins (HDL).

13. Sugar can lead to chromium deficiency.

14. Sugar can lead to ovarian cancer.

15. Sugar can increase fasting levels of glucose.

16. Sugar causes copper deficiency.

17. Sugar interferes with the body’s absorption of calcium and magnesium.

18. Sugar may make eyes more vulnerable to age-related macular degeneration.

19. Sugar raises the level of neurotransmitters: dopamine, serotonin, and norepinephrine.

20. Sugar can cause hypoglycemia.

21. Sugar can lead to an acidic digestive tract.

22. Sugar can cause a rapid rise of adrenaline levels in children.

23. Sugar is frequently malabsorbed in patients with functional bowel disease.

24. Sugar can cause premature aging.

25. Sugar can lead to alcoholism.

26. Sugar can cause tooth decay.

27. Sugar can lead to obesity.

28. Sugar increases the risk of Crohn’s disease and ulcerative colitis.

29. Sugar can cause gastric or duodenal ulcers.

30. Sugar can cause arthritis.

31. Sugar can cause learning disorders in school children.

32. Sugar assists the uncontrolled growth of Candida Albicans (yeast infections).

33. Sugar can cause gallstones.

34. Sugar can cause heart disease.

35. Sugar can cause appendicitis.

36. Sugar can cause hemorrhoids.

37. Sugar can cause varicose veins.

38. Sugar can lead to periodontal disease.

39. Sugar can contribute to osteoporosis.

40. Sugar contributes to saliva acidity.

41. Sugar can cause a decrease in insulin sensitivity.

42. Sugar can lower the amount of Vitamin E in the blood.

43. Sugar can decrease the amount of growth hormones in the body.

44. Sugar can increase cholesterol.

45. Sugar increases advanced glycation end products (AGEs), which form when sugar binds non-enzymatically to protein.

46. Sugar can interfere with the absorption of protein.

47. Sugar causes food allergies.

48. Sugar can contribute to diabetes.

49. Sugar can cause toxemia during pregnancy.

50. Sugar can lead to eczema in children.

51. Sugar can cause cardiovascular disease.

52. Sugar can impair the structure of DNA.

53. Sugar can change the structure of protein.

54. Sugar can make the skin wrinkle by changing the structure of collagen.

55. Sugar can cause cataracts.

56. Sugar can cause emphysema.

57. Sugar can cause atherosclerosis.

58. Sugar can promote an elevation of low-density lipoproteins (LDL).

59. Sugar can impair the physiological homeostasis of many systems in the body.

60. Sugar lowers enzymes ability to function.

61. Sugar intake is associated with the development of Parkinson’s disease.

62. Sugar can increase the size of the liver by making the liver cells divide.

63. Sugar can increase the amount of liver fat.

64. Sugar can increase kidney size and produce pathological changes in the kidney.

65. Sugar can damage the pancreas.

66. Sugar can increase the body’s fluid retention.

67. Sugar is the number one enemy of the bowel movement.

68. Sugar can cause myopia (nearsightedness).

69. Sugar can compromise the lining of the capillaries.

70. Sugar can make tendons more brittle.

71. Sugar can cause headaches, including migraines.

72. Sugar plays a role in pancreatic cancer in women.

73. Sugar can adversely affect children’s grades in school.

74. Sugar can cause depression.

75. Sugar increases the risk of gastric cancer.

76. Sugar can cause dyspepsia (indigestion).

77. Sugar can increase the risk of developing gout.

78. Sugar can increase the levels of glucose in the blood much higher than complex carbohydrates in a glucose tolerance test can.

79. Sugar reduces learning capacity.

80. Sugar can cause two blood proteins – albumin and lipoproteins – to function less effectively, which may reduce the body’s ability to handle fat and cholesterol.

81. Sugar can contribute to Alzheimer’s disease.

82. Sugar can cause platelet adhesiveness, which causes blood clots.

83. Sugar can cause hormonal imbalance – some hormones become underactive and others become overactive.

84. Sugar can lead to the formation of kidney stones.

85. Sugar can cause free radicals and oxidative stress.

86. Sugar can lead to biliary tract cancer.

87. Sugar increases the risk of pregnant adolescents delivering a small-for-gestational-age (SGA) infant.

88. Sugar can lead to a substantial decrease the in the length of pregnancy among adolescents.

89. Sugar slows food’s travel time through the gastrointestinal tract.

90. Sugar increases the concentration of bile acids in stool and bacterial enzymes in the colon, which can modify bile to produce cancer-causing compounds and colon cancer.

91. Sugar increases estradiol (the most potent form of naturally occurring estrogen) in men.

92. Sugar combines with and destroys phosphatase, a digestive enzyme, which makes digestion more difficult.

93. Sugar can be a risk factor for gallbladder cancer.

94. Sugar is an addictive substance.

95. Sugar can be intoxicating, similar to alcohol.

96. Sugar can aggravate premenstrual syndrome (PMS).

97. Sugar can decrease emotional stability.

98. Sugar promotes excessive food intake in obese people.

99. Sugar can worsen the symptoms of children with attention deficit disorder (ADD).

Sugar can slow the ability of the adrenal glands to function. Sugar can cut off oxygen to the brain when given to people intravenously. Sugar is a risk factor for lung cancer. Sugar increases the risk of polio. Sugar can cause epileptic seizures. Sugar can increase systolic blood pressure (pressure when the heart is contracting). Sugar can induce cell death. Sugar can increase the amount of food that you eat. Sugar can cause antisocial behavior in juvenile delinquents. Sugar can lead to prostate cancer. Sugar dehydrates newborns. Sugar can cause women to give birth to babies with low birth weight. Sugar is associated with a worse outcome of schizophrenia. Sugar can raise homocysteine levels in the bloodstream. Sugar increases the risk of breast cancer. Sugar is a risk factor in small intestine cancer. Sugar can cause laryngeal cancer. Sugar induces salt and water retention. Sugar can contribute to mild memory loss. Sugar water, when given to children shortly after birth, results in those children preferring sugar water to regular water throughout childhood. Sugar causes constipation. Sugar can cause brain decay in pre-diabetic and diabetic women. Sugar can increase the risk of stomach cancer. Sugar can cause metabolic syndrome. Sugar increases neural tube defects in embryos when it is consumed by pregnant women. Sugar can cause asthma. Sugar increases the chances of getting irritable bowl syndrome. Sugar can affect central reward systems. Sugar can cause cancer of the rectum. Sugar can cause endometrial cancer. Sugar can cause renal (kidney) cell cancer. Sugar can cause liver tumors. Sugar can increase inflammatory markers in the bloodstreams of overweight people. Sugar plays a role in the cause and the continuation of acne. Sugar can ruin the sex life of both men and women by turning off the gene that controls the sex hormones. Sugar can cause fatigue, moodiness, nervousness, and depression. Sugar can make many essential nutrients less available to cells. Sugar can increase uric acid in blood. Sugar can lead to higher C-peptide concentrations. Sugar causes inflammation. Sugar can cause diverticulitis, a small bulging sac pushing outward from the colon wall that is inflamed. Sugar can decrease testosterone production. Sugar impairs spatial memory. Sugar can cause cataracts. Sugar is associated with higher rates of chronic bronchitis in adults.

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21. Ibid.

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23. Ibid.

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36. Ibid.

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43. Gardner, L. and Reiser, S. “Effects of Dietary Carbohydrate on Fasting Levels of Human Growth Hormone and Cortisol.” Proc Soc Exp Bioi Med. 1982; 169: 36-40.

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45. Furth, A and Harding, J. “Why Sugar Is Bad For You.” New Scientist. Sep 23, 1989; 44.

46. Lee, AT. and Cerami, A “Role of Glycation in Aging.” Annals N Y Acad Sci. Nov 21,1992; 663: 63-70.

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48. Henriksen, H. B. and Kolset, S.O. Tidsslcr Nor Laegeforen. Sep 6, 2007; 127(17): 2259-62.

49. Cleave, T. The Saccharine Disease. (New Canaan, CT: Keats Publishing, 1974).

50. Ibid., at 132.

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54. Dyer, D. G., et al. “Accumulation of Maillard Reaction Products in Skin Collagen in Diabetes and Aging.” J Clin Invest. 1993; 93(6): 421-422.

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58. Lewis, G. F. and Steiner, G. “Acute Effects of Insulin in the Control of VLDL Production in Humans. Implications for The Insulin-resistant State.” Diabetes Care. Apr 1996; 19(4): 390-393.

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60. Appleton, Nancy. Lick the Sugar Habit. (New York: Avery Penguin Putnam, 1988).

61. Hellenbrand, W., et al. “Diet and Parkinson’s Disease. A Possible Role for the Past Intake of Specific Nutrients. Results from a Self-administered Food-frequency Questionnaire in a Case-control Study.” Neurology. Sep 1996; 47: 644-650.

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65. Goulart, F. S. “Are You Sugar Smart?” American Fitness. Mar-Apr 1991: 34-38

66. Ibid.

67. Ibid.

68. Ibid.

69. Ibid.

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71. Grand, E. “Food Allergies and Migraine.” Lancet. 1979; 1: 955-959.

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73. Schauss, A. Diet, Crime and Delinquency. (Berkley, CA: Parker House, 1981).

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75. Cornee, L et al. “A Case-control Study of Gastric Cancer and Nutritional Factors in Marseille, France.” Eur J Epid. 1995; 11: 55-65.

76. Yudkin, J. Sweet and Dangerous. (New York: Bantam Books, 1974).

77. Ibid., at 44.

78. Reiser, S., et al. “Effects of Sugars on Indices on Glucose Tolerance in Humans.” Am J Clin Nutr. 1986: 43; 151-159.

79. Ibid.

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80. Monnier, v., “Nonenzymatic Glycosylation, the Maillard Reaction and the Aging Process.” J Ger. 1990; 45: 105-111.

81. Frey, J. “Is There Sugar in the Alzheimer’s Disease?” Annales De Biologie Clinique. 2001; 59(3): 253-257.

82. Yudkin, J. “Metabolic Changes Induced by Sugar in Relation to Coronary Heart Disease and Diabetes.” Nutr Health. 1987; 5(1-2): 5-8.

83. Ibid.

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85. Ceriello, A “Oxidative Stress and Glycemic Regulation.” Metabolism. Feb 2000; 49(2 Suppl1): 27-29.

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87. Lenders, C. M. “Gestational Age and Infant Size at Birth Are Associated with Dietary Intake among Pregnant Adolescents.” J Nutr. Jun 1997; 1113-1117.

88. Ibid.

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91. Yudkin, J. and Eisa, O. “Dietary Sucrose and Oestradiol Concentration in Young Men.” Ann Nutr Metab. 1988; 32(2): 53-55.

92. Lee, AT. and Cerami, A “The Role of Glycation in Aging.” Annals N Y Acad Sci. 1992; 663: 63-70.

93. Moerman, c., et al.”Dietary Sugar Intake in the Etiology of Gallbladder Tract Cancer.” Inter J Epid. Apr 1993; 22(2): 207-214.

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95. Ibid.

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98. Ludwig, D.S., et al. “High Glycemic Index Foods, Overeating and Obesity.”Pediatrics. Mar 1999; 103(3): 26-32.

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