Move over, Bloods and Crips — the Sharks and the Jets have taken over Harlem.

The screen remake of “West Side Story” filled an uptown Manhattan street with singing and dancing on Saturday, presided over by a smiling, Hawaiian-shirt-clad Steven Spielberg.

East 131st Street between Fifth and Lenox — 10 years ago a notorious drug supermarket — was transformed into the leaping and stomping ground for Keds- and suspenders-wearing 1950s-era hooligans.

As first revealed by Page Six, Spielberg is in Harlem filming several of the dance scenes for the iconic masterpiece.

With music by the great Leonard Bernstein, book by Arthur Laurents and lyrics by a then-young Stephen Sondheim, West Side Story took Broadway by storm in 1957.

It was made into a classic movie in 1961.

Rita Moreno, who won an Oscar for the role of Anita in the movie, will appear in the remake as “Valentina,” a reworked version of the character “Doc,” the owner of the corner store where “Tony” works.

Moreno will also serve as executive producer.

The story follows Tony (Ansel Elgort) and Maria (Rachel Zegler) as star-crossed sweethearts connected to rival gangs, and who are based on Shakespeare’s “Romeo and Juliet.”

Pulitzer- and Tony-winning playwright Tony Kushner of “Angels in America” fame adapted the script.

Choreographer Justin Peck (“Carousel”) is reimagining the then-innovative dance moves of Jerome Robbins.

Gustavo Dudamel of the LA Philharmonic will conduct Bernstein’s sweeping score, and prolific musical theater composer and arranger Jeanine Tesori is serving as vocal coach.

A decade ago, the same neighborhood now overtaken by Jets and Sharks was infested with gangs with names like “Broad Day Shooters,” “Gun Clappin Goonies” and “Money Stackin High.”

Lately, though, East 131 Street has welcomed luxury condominiums, fancy cafes and restaurants.

“West Side Story” is set to be released by Walt Studios Motion Pictures and screen in theaters nationwide Dec. 18, 2020.