MIAMI — High-profile murder cases always raise the question: Will jurors be able to weigh the evidence impartially?

On Monday, the judge presiding over the trial of Casey Anthony, charged with killing her 2-year-old daughter, faced the nearly impossible task of finding jurors who could set aside their own private verdicts after breathless news coverage.

To that end, the judge, Belvin Perry Jr., of the Ninth Judicial Circuit Court, decided to hold the trial in Orlando, where Ms. Anthony was charged, and to import a jury from 100 miles away in Clearwater, near Tampa, hoping jurors there might be less exposed to the intricacies of the case.

This decision will add another hardship for jurors, who will be sequestered for two months in a hotel a two-hour drive from home. Family members will be permitted to visit on weekends.