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The high temperature in Las Vegas is expected to peak around 80 degrees on Wednesday, and you are unlikely to see anyone wearing Santa hats or reindeer-emblazoned sweaters on the Strip, but for certain folks, Wednesday might feel a little like winter in the desert.

After all, the NFL point spreads are back on the board, available to be bet.

According to VegasInsider.com, the Westgate Las Vegas SuperBook has already put up lines for every Week One game after Tuesday’s schedule release.

The biggest favorites of Week One? The Patriots, who are favored by six points over the Steelers in the NFL regular season opener.

The Cowboys are the second-biggest favorites of Week One. Dallas is favored by 5.5 points against the Giants in the first Sunday night game of the season.

Seven teams are road favorites in the opening week: Green Bay (at Chicago), Indianapolis (at Buffalo), Miami (at Washington), Carolina (at Jacksonville), Seattle (at St. Louis), Cincinnati (at Oakland) and Philadelphia (at Atlanta).

Below is the entire Week One NFL slate. Over-Unders are in parentheses, and home teams are in CAPS:

Week One lines (Westgate Las Vegas SuperBook)

Thursday, September 10

NEW ENGLAND -6 vs. Pittsburgh (53)

Sunday, September 13

Green Bay -4 at CHICAGO (50)

HOUSTON -1.5 vs. Kansas City (43)

N.Y. JETS -1 vs. Cleveland (41)

Indianapolis -3 at BUFFALO (48)

Miami -2.5 at WASHINGTON (44)

Carolina -4 at JACKSONVILLE (43.5)

Seattle -3.5 at ST. LOUIS (44)

ARIZONA -2.5 vs. New Orleans (48)

SAN DIEGO -2 vs. Detroit (46.5)

TAMPA BAY -3 vs. Tennessee (42.5)

Cincinnati -3 at OAKLAND (44.5)

DENVER -4 vs. Baltimore (53)

DALLAS -5.5 vs. N.Y. Giants (50)

Monday, September 14

Philadelphia -1.5 at ATLANTA (53.5)

SAN FRANCISCO -3.5 vs. Minnesota (42)