Big Apple businesses crippled by lawsuits from suspect serial plaintiffs gripe that politicians and law enforcement agencies are doing nothing to alleviate the problem.

“I regularly represent small businesses, and this is one example of many where our city officials do nothing to protect businesses against such situations,” said lawyer Andreas Koutsoudakis.

Koutsoudakis represents the East 22nd Street diner Tivoli Cafe — which just stopped its settlement payments to professional plaintiff Arik Matatov after a Post exposé.

The Post revealed last week that Matatov — who has been shaking down dozens of businesses by threatening to sue them for millions of dollars over their lack of handicapped access if they don’t pay him $50,000 — regularly walks around his Queens neighborhood on his own two feet.

Tivoli’s owner, Gus Kassimis, had settled with Matatov and his lawyer, Jeffrey Neiman, for $5,000 earlier this month. Now, Kassimis has stopped settlement payments and is contemplating a countersuit, his lawyer said.

Matatov’s own lawyer has even hit the brakes on all 49 lawsuits he filed on behalf of his client while he investigates his medical history.

But the Manhattan District Attorney’s Office refused to comment on the situation, and the state attorney general’s office said it is passing the buck to the appellate courts.

City Public Advocate Letitia James, who is running for attorney general, also punted on the issue, even though she acknowledged that businesses along Myrtle Avenue in Fort Greene, Brooklyn, have said they’ve been hit with accessibility suits by others like Matatov.

“Obviously, because [Matatov is] engaging in deceptive business practices, there’s a question of whether or not he’s engaged in criminal activity, so primarily the Office of Public Advocate, as you know, doesn’t have criminal prosecution,” she told The Post.

In regards to hammered Fort Greene businesses, James kicked the can across the East River to Brooklyn DA Eric Gonzalez — whose office declined to comment.

“We don’t confirm or deny investigations,” a DA spokesman said.

But at least Susan Ventura, the owner of the Italian restaurant Via Della Pace in the East Village, who was targeted by another allegedly wheelchair-bound plaintiff, has a plan.

After reading about Matatov, she is organizing local businesses to lobby the City Council and mayor for help.

“We hope NYC officials will change the legislation to at least curb these lawsuits,” she said.

“This is becoming such a big problem, especially in downtown Manhattan with the older buildings that are landmarked” and can’t change their entrances to be [Americans with Disabilities Act] compliant,” she said.

One local pol wants to tackle the problem.

“We’re going to be working with business-improvement districts to solve the problem,” Councilwoman Margaret Chin vowed.

Her downtown district includes two stores targeted by Matatov and another plaintiff: Shu’s Flowers on Mulberry Street and Bell’s Coffee and Design on Grand Street.

“They’re just shaking down these small businesses, which is a shame,” Chin said.

Additional reporting by Emily Saul