Sen. John McCain John Sidney McCainBiden's six best bets in 2016 Trump states Replacing Justice Ginsburg could depend on Arizona's next senator The Hill's Morning Report - Sponsored by Facebook - Washington on edge amid SCOTUS vacancy MORE (R-Ariz.) on Sunday lamented that President Trump Donald John TrumpBubba Wallace to be driver of Michael Jordan, Denny Hamlin NASCAR team Graham: GOP will confirm Trump's Supreme Court nominee before the election Southwest Airlines, unions call for six-month extension of government aid MORE's recent talk of withdrawing U.S. troops from Syria appears to have "emboldened" Syrian President Bashar Assad following a reported chemical weapons attack on Saturday.

“President Trump last week signaled to the world that the United States would prematurely withdraw from Syria. Bashar Assad and his Russian and Iranian backers have heard him, and emboldened by American inaction, Assad has reportedly launched another chemical attack against innocent men, women and children, this time in Douma," McCain said in a statement.

He added that Trump should respond militarily, as he did following a similar report last year.

“President Trump was quick to call out Assad today, along with the Russian and Iranian governments, on Twitter,” McCain said.

“The question now is whether he will do anything about it. The President responded decisively when Assad used chemical weapons last year. He should do so again, and demonstrate that Assad will pay a price for his war crimes."

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Dozens of people were killed in an alleged chemical weapons attack on a hospital in Douma, Syria, on Saturday. The death count will likely rise.

The latest attack took place almost one year to the day after Trump ordered missile strikes in response to a similar chemical attack.

Trump on Sunday tweeted there would be a "big price to pay" for the most recent attack. He blamed former President Obama for failing to address the crisis in Syria, and called out Russian President Vladimir Putin and Iran for backing Assad.

“Area of atrocity is in lockdown and encircled by Syrian Army, making it completely inaccessible to outside world. President Putin, Russia and Iran are responsible for backing Animal Assad," Trump tweeted.

Many dead, including women and children, in mindless CHEMICAL attack in Syria. Area of atrocity is in lockdown and encircled by Syrian Army, making it completely inaccessible to outside world. President Putin, Russia and Iran are responsible for backing Animal Assad. Big price... — Donald J. Trump (@realDonaldTrump) April 8, 2018

His stern remarks on Sunday came after he has in recent weeks indicated he'd like to bring U.S. troops home from Syria "very soon," saying the Islamic State in Iraq and Syria is nearly defeated and the U.S. is shouldering a large cost to remain in the region.

McCain on Sunday acknowledged that the U.S. has made policy mistakes in Syria prior to Trump's presidency, but rejected the idea that "we are out of options."

"We can and should change course – starting with a comprehensive strategy that lays out clear objectives for our mission there. It's not too late to stop Assad's impunity and begin to rewrite this terrible chapter in our history," McCain said.