Queensland Police Minister Jo-Ann Miller's job is on the line after an "extraordinary" resolution by her own Labor colleagues on the Parliamentary Crime and Corruption Committee (PCCC).

The PCCC determined there was a prima facie case that Ms Miller deliberately misled it by signing an incorrect statement about the destruction of confidential documents.

Opposition Leader Lawrence Springborg said that was a "clear cut" finding by the Labor Government-dominated committee.

"This is extraordinary language: this is not just saying 'may have', this is not just saying allegations, this is basically saying that she did it," he said.

The case was referred to Parliament's Ethics Committee in a move that technically prevented the Opposition asking questions in budget estimates hearings.

But Mr Springborg pressed ahead and repeatedly called on the Premier to sack Ms Miller from Cabinet under the Ministerial Code of Ethics, which states:

"If a Minister is the subject of an official investigation into a matter of serious impropriety or alleged illegal behaviour of a serious nature, a Minister must accept that to whether the Minister should stand down is a matter of discretion for the Premier."

Premier Annastacia Palaszczuk refused to discuss the issue at the estimates hearing.

"I'm not going to pre-judge anyone, it's a matter for the Ethics Committee," she said.

"We are here to examine the budget.

"I am happy to answer any question you want to put to me about my economic plan for creating jobs in Queensland."

Ms Palaszczuk was initially unaware that her Minister had been referred to the Ethics Committee, when asked earlier on Tuesday if she still supported Ms Miller she replied "Yes, why not?"

Mr Springborg reminded Ms Palaszczuk she had effectively put the Police Minister on a last warning after several other controversies.

He also questioned Ms Miller's referral to the Ethics Committee ahead of her appearance at budget estimates hearings.

"I think it's somewhat coincidental at the very least that on the morning of Estimates we have what appears to be a protection racket," he said.

"There has been a rather dubious process followed by the Government around this."

But Parliamentary Speaker Peter Wellington told Mr Springborg there was no protection racket.

"I think that choice of words is inappropriate," he said.

"I have full confidence in the Ethics Committee being able to consider this matter and come down with the decision."

There will be four days of budget estimates hearings this week and four next week.