New York Giants running back Ahmad Bradshaw had hoped to return from a foot injury in time for Monday night's game against the New Orleans Saints, but his comeback will have to wait at least another week.

The Giants on Saturday afternoon ruled Bradshaw out.

Also ruled out were left tackle Will Beatty (eye/back) and defensive back and special teams contributor Derrick Martin (hamstring).

Linebacker Michael Boley (hamstring) is doubtful, while wide receiver Mario Manningham (knee) is questionable. But Manningham stated emphatically on Friday that he expects to play.

Boley was less certain.

The starting middle linebacker ran for the first time on Friday after missing last weekend's game against Philadelphia with a hamstring injury.

"I don't want to put myself in a situation where I hurt the team or I hurt myself. I'd rather miss another week than miss a few more weeks," he said on Friday.

Defensive linemen Justin Tuck (ankle/shoulder) and Osi Umenyiora (knee), right tackle Kareem McKenzie (toe) and running back D.J. Ware (concussion) are probable.

Bradshaw has missed four games with a cracked bone in his foot. In his absence, Brandon Jacobs should see the bulk of the carries against the Saints.

Jacobs was booed loudly after running for just 21 yards on 12 carries in the Giants' loss to Philly last week.

He said afterward that he didn't care about the boos but said of fans: "That's the best thing they do around here is boo," which rubbed some observers and fans the wrong way.

On Friday, Jacobs, unprompted, was highly complimentary of Giants fans.

"We've got a lot of people that's pulling for us. We've got a lot of great fans that's out there and want us to go out there and do good," Jacobs said. "For all of the people that have supported us from Day 1, we've got to go out there and do our best for them."

Ware and Da'Rel Scott are expected to fill in behind Jacobs. Ware suffered a concussion last Sunday against Philadelphia but practiced for three consecutive days and is expected to play.

As for the offensive line, coach Tom Coughlin did not say who would start in place of Beatty, who underwent surgery to repair a detached retina on Thursday. In all likelihood, guard David Diehl will slide over to tackle. But Coughlin also mentioned reserve Stacy Andrews as a possibility.

If Diehl moves to tackle, Kevin Boothe will likely start at left guard.

Diehl played tackle for most of the past four seasons until injuries forced him to move to guard in the middle of the 2010 season.

"Nothing's been declared yet. I've been playing some [left guard] during practice, playing next to Boothe, next to Stacy as well," Diehl said. "This is nothing new for me. This is part of being a guy who can play multiple positions. If things happen, if guys go down, I'm capable of moving. Obviously, I know what to do at left tackle."

If Boley can't suit up, rookie Mark Herzlich may get his second straight start at middle linebacker.

Herzlich finished with four tackles (two solo) Sunday against Philadelphia.

"I thought he was commanding in the huddle. I thought he was decisive in his reads and I thought he gained a lot of respect from his teammates by the way he played that football game," defensive coordinator Perry Fewell said of Herzlich.

In a roster move announced Saturday, the Giants placed reserve wideout Michael Clayton on injured reserve with a torn meniscus. Clayton will undergo surgery on Monday. Defensive end Justin Trattou was signed off of the practice squad to replace Clayton. Quarterback Ryan Perrilloux was signed to the practice squad.

Clayton is an eight-year veteran who was among the team's final cuts this year. He was re-signed Sept. 23 and played in five games, mostly on special teams.

Trattou, a rookie free agent from Florida, also was among the final cuts. But he was re-signed and played in the Giants' season opener, recording a tackle. He was released four days later and re-signed to the practice squad.

Ian Begley is a regular contributor to ESPNNewYork.com. Information from The Associated Press was used in this report.