The United Nations has rejected a UK appeal against its previous ruling in favor of Julian Assange as "inadmissible," thus requiring both London and Stockholm to end the WikiLeaks founder’s "arbitrary detention."

Earlier this year, a case was concluded at the UN, in which the body instructed the UK and Sweden to take immediate steps to ensure the WikiLeaks founder's liberty, protection and enjoyment of fundamental human rights.

The UK has appealed the ruling twice, with the UN rejecting its second appeal on Wednesday by pronouncing it "not admissible," Justice for Assange reported, adding that the decision marks the end to London's "attempt to overturn the ruling."

READ MORE: UK appeals ‘incorrect’ UN claim that Assange is under ‘arbitrary detention’

"Now that all appeals are exhausted, I expect that the UK and Sweden will comply with their international obligations and set me free," a statement by Assange read, with the fugitive whistleblower calling his detention "an obvious and grotesque injustice."

The recent development in the Assange case at the UN forces the UK and Sweden - which are parties to his case - "to immediately put an end to Mr. Assange's arbitrary detention and afford him monetary compensation," Justice for Assange stated, adding that a failure to do so would undermine the UN human rights' protection system.

Julian Assange faces potential, but as yet unfiled charges over rape allegations in Stockholm that date back to 2010. The whistleblower has always denied the accusations, saying that being taken to Sweden would pave the way for a further extradition to the US, where the government has launched a criminal investigation into WikiLeaks following a 2010 diplomatic cables leak.

READ MORE: Assange ‘finally afforded opportunity’ to give statement to Sweden, complains of ‘irregularities’

He has been sheltered by the Ecuadorian Embassy in London since August 2012. Earlier this month, Swedish investigators came to interview Assange inside the embassy concerning rape charges, with the whistleblower saying he has "cooperated fully" with them.