A High Coverage Denisovan Genome

The genome sequence of a Denisovan individual was generated from a small fragment of a finger bone discovered in Denisova Cave in southern Siberia in 2008.

Approximately 30-fold coverage of the genome was generated using the Illumina GAIIx sequencing platform.

This data is freely available without passwords.

Focussing on the "mappable genome" - the 1.86GB of unique sequence with clear human-chimpanzee orthology - we see 99.97% of bases covered at least 3x and 99.51% covered at least 10x.

Contamination with modern human DNA, estimated from both mitochondrial and nuclear genomes, is less than 1%.