On Friday, Mr. Scott said that the state expected to lift the advisory on the zone of transmission in Wynwood.

The same strategy is playing out in Miami Beach, where active transmission was discovered in mid-August. Mosquito control officials say they are seeing a reduction in the mosquito population since the aerial spraying began. But the reaction has been decidedly different on this island of mostly wealthy, beach- and nightlife-loving people, and those who cater to them.

Protesters here are drawing inspiration from Puerto Rico, where Gov. Alejandro García Padilla rebuffed pressure this summer from the Centers for Disease Control and Prevention to spray naled. Puerto Rico is now in the throes of an epidemic, with nearly 20,000 reported cases of Zika. As of Friday night, Florida had 93 cases of local transmission. The virus is particularly dangerous for pregnant women because it can cause severe brain abnormalities and other problems in fetuses.

“No one likes the aerial spraying. I don’t like it. I don’t want it. We have a choice. Do we become Puerto Rico, or do we eliminate or eradicate this virus?” said Mayor Philip Levine of Miami Beach, who emphasized that the federal government had found naled to be safe in the dose being used.

Mr. Levine said a balance must be struck between fear of naled and protecting pregnant women.

But residents said they were also seeking a balance, arguing that the level of Zika mosquitoes in Miami Beach is not so alarming to warrant continued use of naled. They argue that people are out and about in Miami Beach on weekends at 6 a.m., which is typically when the spraying occurs.

“My main issue is that all safe options should be explored before you take something out that on the labels says can cause birth defects,” said Diane Fragale, a holistic practitioner.

Ms. Fragale, who lives near the aerial spraying, said she did not believe it was a coincidence that hours after the first naled application she developed sties in her eyes, something she said had never happened. Ms. Fragale said she had followed the county’s advice and shut off her air-conditioning and stayed indoors.