OTTAWA — The government of Canada formally declared bisphenol A, a chemical widely used to create clear, hard plastics, as well as food can liners, to be a toxic substance on Wednesday.

The compound, commonly known as BPA, has been shown to disrupt the hormone systems of animals and is under review in the United States and Europe.

Canada’s move, which was strenuously fought by the chemical industry, followed an announcement by the government two years ago that it would eliminate the compound’s use in polycarbonate bottles used by infants and children.

The compound was formally listed as being toxic to both the environment and human health in an official notice published online by the government without fanfare, a noticeable contrast to the earlier baby bottle announcement, which was made by two cabinet ministers.