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Of all the things you thought were bad about weighing more than you’d like, you might not have thought of this: a possible unwanted pregnancy.

Research is raising new concerns that the most popular type of emergency contraception – morning-after pills made from the hormone levonorgestrel, which prevents ovulation – are less effective in women who weigh more than 165 pounds. (To put this in context, the average weight of American women in their 20s is 162 pounds; in their 30s, 169 pounds, according to the Centers for Disease Control and Prevention.)

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Writing in Women’s Health magazine, Elizabeth Dawes Gay starts with some background: In 2013, the European-made Norlevo added a warning on its packaging that the morning-after pill begins to lose effectiveness among women who weigh 165 pounds and isn’t effective at all for women weighing more than 175. Although Norlevo is chemically identical to Plan B in the United States, the Food and Drug Administration said the data was inconclusive and did not require a warning here.