Perth Scorchers spoiled the party for former Australia quick Brett Lee after winning back-to-back Big Bash League titles with a thrilling four-wicket triumph over Sydney Sixers in Canberra on Wednesday evening.

The Scorchers snuck home with the last ball at Manuka Oval after a cameo by England Test batsman Michael Carberry (9 off seven balls) nudged them past the Sixers' target of 148.

In a final that took numerous twists and turns, the Sixers failed in their chance to tie the match and force a super over after botching a run-out opportunity with the last ball.

Captain Moises Henriques fumbled a throw at the stumps with Yasir Arafat well short of the crease.

The match came down to Lee's final over with the Scorchers requiring eight runs.

Just when it looked like the Scorchers would get over the line with a few balls up their sleeve, Lee (3 for 25) removed Nathan Coulter-Nile and Sam Whiteman with successive balls.

"Back-to-back champions, we are very proud of that and we will enjoy tonight," the Scorchers' Shaun Marsh told Grandstand.

Sorry, this audio has expired Interview: Shaun Marsh

Earlier, Marsh provided the platform for the Scorchers' win, hitting 73 off 59.

The match was 38-year-old Lee's last in a career that included 76 Tests, 221 one-day internationals and 116 first-class matches.

The Sixers looked to have fallen short after setting the Scorchers 148 for victory.

Gallant effort ... Brett Lee (R) celebrates with Nathan Lyon after taking the wicket of Michael Klinger ( Getty Images: Matt King )

Lee and Australia Test spinner Nathan Lyon (2 for 34) took wickets at key moments but could not do enough.

Henriques and Ryan Carters produced some late hitting to guide the Sixers to 5 for 147.

The Sixers looked to be in big trouble at 4 for 54 after 10 overs, after the Perth attack ripped through their top order.

Looking for runs ... Michael Klinger takes on the Sixers attack ( Getty Images: Matt King )

But Henriques (77 off 57) and Carters (35 off 25) dragged the Sixers back into the contest during a 98-run partnership for the fifth wicket.

Jason Behrendorff, who the night before was named Australian domestic cricketer of the year at the Allan Border Medal ceremony, led the Scorchers attack with 1 for 19 off four overs.

Behrendorff, Nathan Coulter-Nile, Yasir Arafat and Brad Hogg all took one wicket each for the Scorchers.

AAP