Sen. Elizabeth Warren Elizabeth WarrenHarris joins women's voter mobilization event also featuring Pelosi, Gloria Steinem, Jane Fonda Judd Gregg: The Kamala threat — the Californiaization of America GOP set to release controversial Biden report MORE (D-Mass.) put gender front and center in a fundraising campaign circulated Friday.

The 2020 Democratic presidential candidate sent out an email Friday under the subject line "Yes, there is a double standard," detailing obstacles she’s faced throughout the years as a woman running for public office.

Warren, who has served as a senator since 2013, said she has faced “plenty of naysayers” over her political career.

"When I started running for Senate, reporters would sometimes ask me a variation of this question: 'What’s it like to run as a woman?'" Warren wrote in an email to supporters.

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"I always smiled mildly, but I hated the question. I was pretty sure no one asked Scott Brown how it felt to run as a man," she continued. "Yes, there was a double-standard. Yes, I always winced when I saw a news report that started with a description of my appearance."

Warren added that she feels buoyed by what she sees as a surge of energy among female voters ahead of the 2020 election cycle.

"But make no mistake: Women were fired up when I was running in 2012, and we’re burning up even hotter right now," she wrote.

“Since Donald Trump Donald John TrumpOmar fires back at Trump over rally remarks: 'This is my country' Pelosi: Trump hurrying to fill SCOTUS seat so he can repeal ObamaCare Trump mocks Biden appearance, mask use ahead of first debate MORE was elected, women have powered this fight like never before. Organizing marches. Saving health care for tens of millions of Americans," she continued.

The senator said women had gained political momentum in recent years, with a record number running for and winning political office, and more women supporting candidates with "unprecedented numbers of grassroots donations."

“The TV talking heads and Twitter pundits might tell us to smile more and stop being so shrill or bossy. And oh yes, there’s that L word: ‘Likeable.’ Is she likeable enough? Nevertheless, we persist," she wrote. "Once again, we’ll prove the naysayers wrong. We’re running on big ideas that will touch people’s lives, and we’re not stopping now.”

The email includes a link to donate and receive a “Persist” sticker from her campaign, referring to a now-famous incident on the Senate floor in which Senate Majority Leader Mitch McConnell Addison (Mitch) Mitchell McConnellPelosi: Trump hurrying to fill SCOTUS seat so he can repeal ObamaCare Senate GOP aims to confirm Trump court pick by Oct. 29: report Trump argues full Supreme Court needed to settle potential election disputes MORE (R-Ky.) cut off one of Warren’s speeches, saying she violated a Senate rule but “nevertheless, she persisted.”

Critics pounced swiftly on McConnell for what they deemed a sexist attempt to silence Warren, catapulting the phrase “nevertheless, she persisted” to become a rallying cry among Warren's supporters.

Warren is among a crowded Democratic field that features an unprecedented number of women running for the presidency, including fellow Sens. Kirsten Gillibrand Kirsten GillibrandSunday shows preview: Justice Ginsburg dies, sparking partisan battle over vacancy before election Suburban moms are going to decide the 2020 election Jon Stewart urges Congress to help veterans exposed to burn pits MORE (N.Y.), Kamala Harris Kamala HarrisButtigieg stands in as Pence for Harris's debate practice First presidential debate to cover coronavirus, Supreme Court Harris joins women's voter mobilization event also featuring Pelosi, Gloria Steinem, Jane Fonda MORE (Calif.) and Amy Klobuchar Amy KlobucharSocial media platforms put muscle into National Voter Registration Day Battle lines drawn on precedent in Supreme Court fight Sunday shows - Ruth Bader Ginsburg's death dominates MORE (Minn.).