Aoi W.

Naito Y.

Takagi T.

Tanimura Y.

Takanami Y.

Kawai Y.

Sakuma K.

Hang L.P.

Mizushima K.

Hirai Y.

et al. A novel myokine, secreted protein acidic and rich in cysteine (SPARC), suppresses colon tumorigenesis via regular exercise. Gut. 62 : 882-889 View in Article Scopus (110)

PubMed

Crossref

Google Scholar

Ashcraft K.A.

Peace R.M.

Betof A.S.

Dewhirst M.W.

Jones L.W. Efficacy and mechanisms of aerobic exercise on cancer initiation, progression, and metastasis: a critical systematic review of in vivo preclinical data. Cancer Res. 76 : 4032-4050 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Atherton P.J.

Babraj J.

Smith K.

Singh J.

Rennie M.J.

Wackerhage H. Selective activation of AMPK-PGC-1alpha or PKB-TSC2-mTOR signaling can explain specific adaptive responses to endurance or resistance training-like electrical muscle stimulation. FASEB J. 19 : 786-788 View in Article PubMed

Crossref

Google Scholar

Betof A.S.

Lascola C.D.

Weitzel D.

Landon C.

Scarbrough P.M.

Devi G.R.

Palmer G.

Jones L.W.

Dewhirst M.W. Modulation of murine breast tumor vascularity, hypoxia and chemotherapeutic response by exercise. J. Natl. Cancer Inst. 107 : djv040 View in Article Scopus (73)

PubMed

Crossref

Google Scholar

Caruso R.

Nanni M.G.

Riba M.

Sabato S.

Mitchell A.J.

Croce E.

Grassi L. Depressive spectrum disorders in cancer: prevalence, risk factors and screening for depression: a critical review. Acta Oncol. 56 : 146-155 View in Article Scopus (55)

PubMed

Crossref

Google Scholar

Cavalheri V.

Granger C. Preoperative exercise training for patients with non-small cell lung cancer. Cochrane Database Syst. Rev. 6 : CD012020 View in Article PubMed

Google Scholar

Chen Q.

Fisher D.T.

Clancy K.A.

Gauguet J.M.

Wang W.C.

Unger E.

Rose-John S.

von Andrian U.H.

Baumann H.

Evans S.S. Fever-range thermal stress promotes lymphocyte trafficking across high endothelial venules via an interleukin 6 trans-signaling mechanism. Nat. Immunol. 7 : 1299-1308 View in Article Scopus (144)

PubMed

Crossref

Google Scholar

Colbert L.H.

Westerlind K.C.

Perkins S.N.

Haines D.C.

Berrigan D.

Donehower L.A.

Fuchs-Young R.

Hursting S.D. Exercise effects on tumorigenesis in a p53-deficient mouse model of breast cancer. Med. Sci. Sports Exerc. 41 : 1597-1605 View in Article Scopus (32)

PubMed

Crossref

Google Scholar

Conlon K.C.

Lugli E.

Welles H.C.

Rosenberg S.A.

Fojo A.T.

Morris J.C.

Fleisher T.A.

Dubois S.P.

Perera L.P.

Stewart D.M.

et al. Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer. J. Clin. Oncol. 33 : 74-82 View in Article Scopus (251)

PubMed

Crossref

Google Scholar

Cooney G.M.

Dwan K.

Greig C.A.

Lawlor D.A.

Rimer J.

Waugh F.R.

McMurdo M.

Mead G.E. Exercise for depression. Cochrane Database Syst. Rev. 9 : CD004366 View in Article PubMed

Crossref

Google Scholar

Dethlefsen C.

Lillelund C.

Midtgaard J.

Andersen C.

Pedersen B.K.

Christensen J.F.

Hojman P. Exercise regulates breast cancer cell viability: systemic training adaptations versus acute exercise responses. Breast Cancer Res. Treat. 159 : 469-479 View in Article Scopus (21)

PubMed

Crossref

Google Scholar

Dethlefsen C.

Hansen L.S.

Lillelund C.

Andersen C.

Gehl J.

Christensen J.F.

Pedersen B.K.

Hojman P. Exercise-induced catecholamines activate the hippo tumor suppressor pathway to reduce risks of breast cancer development. Cancer Res. 77 : 4894-4904 View in Article PubMed

Crossref

Google Scholar

Evans E.S.

Hackney A.C.

McMurray R.G.

Randell S.H.

Muss H.B.

Deal A.M.

Battaglini C.L. Impact of acute intermittent exercise on natural killer cells in breast cancer survivors. Integr. Cancer Ther. 14 : 436-445 View in Article Scopus (17)

PubMed

Crossref

Google Scholar

Fischer K.

Hoffmann P.

Voelkl S.

Meidenbauer N.

Ammer J.

Edinger M.

Gottfried E.

Schwarz S.

Rothe G.

Hoves S.

et al. Inhibitory effect of tumor cell-derived lactic acid on human T cells. Blood. 109 : 3812-3819 View in Article Scopus (602)

PubMed

Crossref

Google Scholar

Fisher D.T.

Chen Q.

Skitzki J.J.

Muhitch J.B.

Zhou L.

Appenheimer M.M.

Vardam T.D.

Weis E.L.

Passanese J.

Wang W.C.

et al. IL-6 trans-signaling licenses mouse and human tumor microvascular gateways for trafficking of cytotoxic T cells. J. Clin. Invest. 121 : 3846-3859 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Friedenreich C.M.

O’Reilly R.

Shaw E.

Stanczyk F.Z.

Yasui Y.

Brenner D.R.

Courneya K.S. Inflammatory marker changes in postmenopausal women after a year-long exercise intervention comparing high versus moderate volumes. Cancer Prev. Res. (Phila.). 9 : 196-203 View in Article Scopus (2)

PubMed

Crossref

Google Scholar

Gallot Y.S.

Durieux A.C.

Castells J.

Desgeorges M.M.

Vernus B.

Plantureux L.

Rémond D.

Jahnke V.E.

Lefai E.

Dardevet D.

et al. Myostatin gene inactivation prevents skeletal muscle wasting in cancer. Cancer Res. 74 : 7344-7356 View in Article Scopus (36)

PubMed

Crossref

Google Scholar

Galvão D.A.

Taaffe D.R.

Spry N.

Joseph D.

Newton R.U. Combined resistance and aerobic exercise program reverses muscle loss in men undergoing androgen suppression therapy for prostate cancer without bone metastases: a randomized controlled trial. J. Clin. Oncol. 28 : 340-347 View in Article Scopus (360)

PubMed

Crossref

Google Scholar

Gannon N.P.

Vaughan R.A.

Garcia-Smith R.

Bisoffi M.

Trujillo K.A. Effects of the exercise-inducible myokine irisin on malignant and non-malignant breast epithelial cell behavior in vitro. Int. J. Cancer. 136 : E197-E202 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Garcia E.

Becker V.G.

McCullough D.J.

Stabley J.N.

Gittemeier E.M.

Opoku-Acheampong A.B.

Sieman D.W.

Behnke B.J. Blood flow responses to mild-intensity exercise in ectopic vs. orthotopic prostate tumors; dependence upon host tissue hemodynamics and vascular reactivity. J. Appl. Physiol. 121 : 15-24 View in Article Scopus (2)

PubMed

Crossref

Google Scholar

Higgins K.A.

Park D.

Lee G.Y.

Curran W.J.

Deng X. Exercise-induced lung cancer regression: mechanistic findings from a mouse model. Cancer. 120 : 3302-3310 View in Article PubMed

Crossref

Google Scholar

Hojman P.

Fjelbye J.

Zerahn B.

Christensen J.F.

Dethlefsen C.

Lonkvist C.K.

Brandt C.

Gissel H.

Pedersen B.K.

Gehl J. Voluntary exercise prevents cisplatin-induced muscle wasting during chemotherapy in mice. PLoS One. 9 : e109030 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Hvid T.

Winding K.

Rinnov A.

Dejgaard T.

Thomsen C.

Iversen P.

Brasso K.

Mikines K.J.

van Hall G.

Lindegaard B.

et al. Endurance training improves insulin sensitivity and body composition in prostate cancer patients treated with androgen deprivation therapy. Endocr. Relat. Cancer. 20 : 621-632 View in Article Scopus (9)

PubMed

Crossref

Google Scholar

Imayama I.

Ulrich C.M.

Alfano C.M.

Wang C.

Xiao L.

Wener M.H.

Campbell K.L.

Duggan C.

Foster-Schubert K.E.

Kong A.

et al. Effects of a caloric restriction weight loss diet and exercise on inflammatory biomarkers in overweight/obese postmenopausal women: a randomized controlled trial. Cancer Res. 72 : 2314-2326 View in Article Scopus (137)

PubMed

Crossref

Google Scholar

Jiang W.

Zhu Z.

Thompson H.J. Effects of limiting energy availability via diet and physical activity on mammalian target of rapamycin-related signaling in rat mammary carcinomas. Carcinogenesis. 34 : 378-387 View in Article Scopus (6)

PubMed

Crossref

Google Scholar

Jones S.B.

Thomas G.A.

Hesselsweet S.D.

Alvarez-Reeves M.

Yu H.

Irwin M.L. Effect of exercise on markers of inflammation in breast cancer survivors: the Yale exercise and survivorship study. Cancer Prev. Res. (Phila.). 6 : 109-118 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Jones L.W.

Kwan M.L.

Weltzien E.

Chandarlapaty S.

Sternfeld B.

Sweeney C.

Bernard P.S.

Castillo A.

Habel L.A.

Kroenke C.H.

et al. Exercise and prognosis on the basis of clinicopathologic and molecular features in early-stage breast cancer: the LACE and pathways studies. Cancer Res. 76 : 5415-5422 View in Article Scopus (4)

PubMed

Crossref

Google Scholar

Kurgan N.

Tsakiridis E.

Kouvelioti R.

Moore J.

Klentrou P.

Tsiani E. Inhibition of human lung cancer cell proliferation and survival by post-exercise serum is associated with the inhibition of Akt, mTOR, p70 S6K, and Erk1/2. Cancers (Basel). 9 : E46 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Lee C.

Safdie F.M.

Raffaghello L.

Wei M.

Madia F.

Parrella E.

Hwang D.

Cohen P.

Bianchi G.

Longo V.D. Reduced levels of IGF-I mediate differential protection of normal and cancer cells in response to fasting and improve chemotherapeutic index. Cancer Res. 70 : 1564-1572 View in Article Scopus (128)

PubMed

Crossref

Google Scholar

Lin C.

Clark R.

Tu P.

Bosworth H.B.

Zullig L.L. Breast cancer oral anti-cancer medication adherence: a systematic review of psychosocial motivators and barriers. Breast Cancer Res. Treat. 165 : 247-260 View in Article Scopus (19)

PubMed

Crossref

Google Scholar

Lu Y.P.

Lou Y.R.

Nolan B.

Peng Q.Y.

Xie J.G.

Wagner G.C.

Conney A.H. Stimulatory effect of voluntary exercise or fat removal (partial lipectomy) on apoptosis in the skin of UVB light-irradiated mice. Proc. Natl. Acad. Sci. USA. 103 : 16301-16306 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Marçais A.

Cherfils-Vicini J.

Viant C.

Degouve S.

Viel S.

Fenis A.

Rabilloud J.

Mayol K.

Tavares A.

Bienvenu J.

et al. The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells. Nat. Immunol. 15 : 749-757 View in Article Scopus (211)

PubMed

Crossref

Google Scholar

McCullough D.J.

Nguyen L.M.

Siemann D.W.

Behnke B.J. Effects of exercise training on tumor hypoxia and vascular function in the rodent preclinical orthotopic prostate cancer model. J. Appl. Physiol. 115 : 1846-1854 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

McCullough D.J.

Stabley J.N.

Siemann D.W.

Behnke B.J. Modulation of blood flow, hypoxia, and vascular function in orthotopic prostate tumors during exercise. J. Natl. Cancer Inst. 106 : dju036 View in Article Scopus (46)

PubMed

Crossref

Google Scholar

Mishra S.I.

Scherer R.W.

Geigle P.M.

Berlanstein D.R.

Topaloglu O.

Gotay C.C.

Snyder C. Exercise interventions on health-related quality of life for cancer survivors. Cochrane Database Syst. Rev. 8 : CD007566 View in Article PubMed

Crossref

Google Scholar

Mishra S.I.

Scherer R.W.

Snyder C.

Geigle P.M.

Berlanstein D.R.

Topaloglu O. Exercise interventions on health-related quality of life for people with cancer during active treatment. Cochrane Database Syst. Rev. https://doi.org/10.1002/14651858.CD008465.pub2 View in Article Scopus (417)

Crossref

Google Scholar

Moore S.C.

Lee I.M.

Weiderpass E.

Campbell P.T.

Sampson J.N.

Kitahara C.M.

Keadle S.K.

Arem H.

Berrington de Gonzalez A.

Hartge P.

et al. Association of leisure-time physical activity with risk of 26 types of cancer in 1.44 million adults. JAMA Intern. Med. 176 : 816-825 View in Article Scopus (382)

PubMed

Crossref

Google Scholar

Morikawa T.

Kuchiba A.

Yamauchi M.

Meyerhardt J.A.

Shima K.

Nosho K.

Chan A.T.

Giovannucci E.

Fuchs C.S.

Ogino S. Association of CTNNB1 (beta-catenin) alterations, body mass index, and physical activity with survival in patients with colorectal cancer. JAMA. 305 : 1685-1694 View in Article Scopus (137)

PubMed

Crossref

Google Scholar

Newby T.A.

Graff J.N.

Ganzini L.K.

McDonagh M.S. Interventions that may reduce depressive symptoms among prostate cancer patients: a systematic review and meta-analysis. Psychooncology. 24 : 1686-1693 View in Article PubMed

Crossref

Google Scholar

Nilsen T.S.

Thorsen L.

Fosså S.D.

Wiig M.

Kirkegaard C.

Skovlund E.

Benestad H.B.

Raastad T. Effects of strength training on muscle cellular outcomes in prostate cancer patients on androgen deprivation therapy. Scand. J. Med. Sci. Sports. 26 : 1026-1035 View in Article Scopus (2)

PubMed

Crossref

Google Scholar

Rundqvist H.

Augsten M.

Strömberg A.

Rullman E.

Mijwel S.

Kharaziha P.

Panaretakis T.

Gustafsson T.

Östman A. Effect of acute exercise on prostate cancer cell growth. PLoS One. 8 : e67579 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Sasso J.P.

Eves N.D.

Christensen J.F.

Koelwyn G.J.

Scott J.

Jones L.W. A framework for prescription in exercise-oncology research. J. Cachexia Sarcopenia Muscle. 6 : 115-124 View in Article PubMed

Crossref

Google Scholar

Schadler K.L.

Thomas N.J.

Galie P.A.

Bhang D.H.

Roby K.C.

Addai P.

Till J.E.

Sturgeon K.

Zaslavsky A.

Chen C.S.

Ryeom S. Tumor vessel normalization after aerobic exercise enhances chemotherapeutic efficacy. Oncotarget. 7 : 65429-65440 View in Article Scopus (6)

PubMed

Crossref

Google Scholar

Schlittler M.

Goiny M.

Agudelo L.Z.

Venckunas T.

Brazaitis M.

Skurvydas A.

Kamandulis S.

Ruas J.L.

Erhardt S.

Westerblad H.

Andersson D.C. Endurance exercise increases skeletal muscle kynurenine aminotransferases and plasma kynurenic acid in humans. Am. J. Physiol. Cell Physiol. 310 : C836-C840 View in Article Scopus (42)

PubMed

Crossref

Google Scholar

Schmitz K.H.

Courneya K.S.

Matthews C.

Demark-Wahnefried W.

Galvão D.A.

Pinto B.M.

Irwin M.L.

Wolin K.Y.

Segal R.J.

Lucia A.

et al.

American College of Sports Medicine American College of Sports Medicine roundtable on exercise guidelines for cancer survivors. Med. Sci. Sports Exerc. 42 : 1409-1426 View in Article Scopus (1483)

PubMed

Crossref

Google Scholar

Tasdemir N.

Banito A.

Roe J.S.

Alonso-Curbelo D.

Camiolo M.

Tschaharganeh D.F.

Huang C.H.

Aksoy O.

Bolden J.E.

Chen C.C.

et al. BRD4 connects enhancer remodeling to senescence immune surveillance. Cancer Discov. 6 : 612-629 View in Article PubMed

Crossref

Google Scholar

Theriau C.F.

Shpilberg Y.

Riddell M.C.

Connor M.K. Voluntary physical activity abolishes the proliferative tumor growth microenvironment created by adipose tissue in animals fed a high fat diet. J. Appl. Physiol. 121 : 139-153 View in Article Scopus (3)

PubMed

Crossref

Google Scholar

van Gemert W.A.

Monninkhof E.M.

May A.M.

Elias S.G.

van der Palen J.

Veldhuis W.

Stapper M.

Stellato R.K.

Schuit J.A.

Peeters P.H. Association between changes in fat distribution and biomarkers for breast cancer. Endocr. Relat. Cancer. 24 : 297-305 View in Article Scopus (9)

PubMed

Crossref

Google Scholar