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Ramona Singer had a “meltdown,” spies said, when she confronted publicist Anna Rothschild at a swanky Hamptons party and accused the PR pro of tattling about Singer and her ex-husband.

We’re told the “Real Housewives of New York” star ambushed Rothschild at a bash for socialite Paola Rosenshein’s birthday on Friday, and accused the PR whiz of gossiping about Mario Singer’s 2014 affair with Kyle “Kasey” Dexter.

Witnesses said Ramona — who divorced Mario last year — “had a meltdown” and “screamed” at Rothschild, saying she was “evil, horrible . . . you broke up my family.”

Rothschild responded, “Your husband was the one who left you and broke up your family.”

Singer insisted, “I merely expressed to her that I felt it was a low blow to . . . [release] private information on my then-marriage and family.”

Others who attended and may have witnessed the scene included Luann de Lesseps and skin-care guru Peter Thomas Roth.