A big rig slammed into Tom’s Jr. Burger in South L.A. following a crash on March 13, 2016. (Credit: KTLA)

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Two drivers suffered serious injuries after a crash that ended with a big rig slamming into a South Los Angeles burger restaurant on Sunday morning.

The collision occurred near the intersection of South Hoover Street and West Florence Avenue -- in the Vermont-Slauson neighborhood of South L.A. -- about 3:09 a.m., according to the California Highway Patrol’s incident log.

The big rig collided with a compact car, sending the semi crashing through Tom's Jr. Burger and resulting in both male drivers becoming trapped in their vehicles.

After being extricated, the drivers were taken to local hospitals in serious condition, said Los Angeles Police Department Sgt. Cory Meisner said.

No one was inside the eatery, which had been closed for several hours at the time of the collision, according to the owner's cousin. The restaurant's structure was severely damaged in the crash, video showed.

The cause of the collision was not immediately known.

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