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Brexit has already wiped £40 billion off Britain’s annual economic growth since the 2016 referendum, a top Bank of England official revealed today.

Gertjan Vlieghe said it amounted to £800 million per week of “lost income for the country” -- more than twice as much as the £350 million a week that the Vote Leave campaign claimed could be “saved” by quitting the European Union.

Mark Rutte, the Dutch premier and one of Britain’s closest EU allies, said the UK would be “weaker” after Brexit and “too small to appear on the world stage on its own”.

International Trade Secretary Liam Fox rounded on Tory Right wingers threatening to defeat Theresa May in the Commons tonight, accusing them of behaving like an “internal debating society” and risking the “wrong signals” that would undermine her backstop negotiations.

Germany avoided a technical recession by a whisker — and the country’s economy ministry blamed Brexit “uncertainty” for holding back the EU’s biggest economy.

One of Jeremy Corbyn’s closest allies moved against a second in-out referendum. Unite union boss Len McCluskey told ITV’s Peston show that a re-run of the 2016 vote “threatens the whole democratic fabric on which we operate” and was “not the best option for our nation”.

Brexit: Leave and Remain supporters gather in London on 29 January 25 show all Brexit: Leave and Remain supporters gather in London on 29 January 1/25 Pro-EU and pro-Brexit protestors discuss the vote and ongoing political processes as they demonstrate near to the Houses of Parliament Getty Images 2/25 A man holds a 'Stop Brexit' sign aboard a campaign bus travelling down Whitehall in Westminster, London PA 3/25 Pro-Brexit demonstrators chant slogans outside the Houses of Parliament Reuters 4/25 Anti-Brexit demonstrators protest outside the Houses of Parliament Reuters 5/25 A leave supporter vapes electronic cigarette in front of a group of remain supporters AP 6/25 Pro-Brexit protestors dressed as suffragettes demonstrate outside the Houses of Parliament Getty Images 7/25 An anti-brexit supporter holds banners in London AP 8/25 Pro and anti Brexit protestors discuss the vote and ongoing political processes as they demonstrate near to the Houses of Parliament Getty Images 9/25 Pro-Brexit and anti-Brexit protesters hold banners in London AP 10/25 A campaigner dressed as Charlie Chaplin walks by the Houses of Parliament PA 11/25 A leave supporter holds banners at the parliament gates AP 12/25 Pro-Brexit, left and anti-Brexit protesters hold banners in London AP 13/25 Pro-Brexit demonstrators protest outside the Houses of Parliament Reuters 14/25 A leave supporter holds banners in front of remain supporters during demonstrations in London AP 15/25 Police officers stand near Pro-Brexit and Anti-Brexit posters outside the Houses of Parliament, in Westminster, London Reuters 16/25 Leave supporters hold placards in front of remain supporters during demonstrations in London, AP 17/25 A pro-Brexit protestor sets fire to a roll of toilet paper decorated with the EU flag as she demonstrates near the Houses of Parliament Getty Images 18/25 A pro-Brexit protestor sets fire to a roll of toilet paper decorated with the EU flag as she demonstrates near the Houses of Parliament Getty Images 19/25 Leave supporters hold placards as they take part in demonstrations near the parliament in Londo AP 20/25 Leave and remain supporters hold placards as they take part in demonstrations near the parliament in London AP 21/25 Pro-Brexit activists hold placards and wave flags as they demonstrate opposite the Houses of Parliament in London AFP/Getty Images 22/25 A remain supporter, left and a leave supporter, center, discuss during demonstrations in London AP 23/25 Pro-Brexit protesters demonstrate outside the Houses of Parliament in Westminster Getty Images 24/25 v Reuters 25/25 Anti-Brexit protesters demonstrate on a double decker bus outside the Houses of Parliament in Westminster Getty Images 1/25 Pro-EU and pro-Brexit protestors discuss the vote and ongoing political processes as they demonstrate near to the Houses of Parliament Getty Images 2/25 A man holds a 'Stop Brexit' sign aboard a campaign bus travelling down Whitehall in Westminster, London PA 3/25 Pro-Brexit demonstrators chant slogans outside the Houses of Parliament Reuters 4/25 Anti-Brexit demonstrators protest outside the Houses of Parliament Reuters 5/25 A leave supporter vapes electronic cigarette in front of a group of remain supporters AP 6/25 Pro-Brexit protestors dressed as suffragettes demonstrate outside the Houses of Parliament Getty Images 7/25 An anti-brexit supporter holds banners in London AP 8/25 Pro and anti Brexit protestors discuss the vote and ongoing political processes as they demonstrate near to the Houses of Parliament Getty Images 9/25 Pro-Brexit and anti-Brexit protesters hold banners in London AP 10/25 A campaigner dressed as Charlie Chaplin walks by the Houses of Parliament PA 11/25 A leave supporter holds banners at the parliament gates AP 12/25 Pro-Brexit, left and anti-Brexit protesters hold banners in London AP 13/25 Pro-Brexit demonstrators protest outside the Houses of Parliament Reuters 14/25 A leave supporter holds banners in front of remain supporters during demonstrations in London AP 15/25 Police officers stand near Pro-Brexit and Anti-Brexit posters outside the Houses of Parliament, in Westminster, London Reuters 16/25 Leave supporters hold placards in front of remain supporters during demonstrations in London, AP 17/25 A pro-Brexit protestor sets fire to a roll of toilet paper decorated with the EU flag as she demonstrates near the Houses of Parliament Getty Images 18/25 A pro-Brexit protestor sets fire to a roll of toilet paper decorated with the EU flag as she demonstrates near the Houses of Parliament Getty Images 19/25 Leave supporters hold placards as they take part in demonstrations near the parliament in Londo AP 20/25 Leave and remain supporters hold placards as they take part in demonstrations near the parliament in London AP 21/25 Pro-Brexit activists hold placards and wave flags as they demonstrate opposite the Houses of Parliament in London AFP/Getty Images 22/25 A remain supporter, left and a leave supporter, center, discuss during demonstrations in London AP 23/25 Pro-Brexit protesters demonstrate outside the Houses of Parliament in Westminster Getty Images 24/25 v Reuters 25/25 Anti-Brexit protesters demonstrate on a double decker bus outside the Houses of Parliament in Westminster Getty Images

Speaking in London, Mr Vlieghe said Britain would be growing two per cent faster if the referendum had voted for Remain. “Based on what happened in the rest of the world we would have expected UK growth to accelerate, but actually it slowed,” he told the Resolution Foundation.

Crashing out of the European Union without a deal would force emergency measures to prevent the economy stalling, such as a cut in interest rates, he warned. The comments by Dutch premier Mr Rutte to a Spanish newspaper were particularly worrying because he has supported Britain on the European stage. “It is the UK that will be weakened,” he said. “It is already weakening; it is on the wane compared to two or three years ago.

“It is going to become a middling economy stuck in the Atlantic Ocean. It is neither the US nor the EU. It is too small to appear on the world stage on its own.” On Mrs May’s attempts to change the Irish backstop and save her deal, he said: “I do not know how this will end and whether we can avoid a hard Brexit. It would be devastating for the UK.”

Mr Fox delivered a warning to Tory Right-wingers to call off a Brexit revolt. “I think that there’s a danger that we send the wrong signals,” he told BBC Radio 4’s Today programme. “What we say is looked at and listened to by those that we are negotiating with.” He said EU leaders would be “watching our debate” and if Mrs May was defeated they would conclude it was pointless to make concessions as she could not deliver in Parliament.

Former Brexit minister Steve Baker responded by calling it a “storm in a tea cup” but said members of the European Research Group would only decide at the last minute whether to back down. “Is the EU really hanging on a non-binding motion at 5pm on a Thursday afternoon?” he asked.

Rebuking the whips for bringing forward a badly drawn motion, he added: “This unnecessary carry-on is wanted by no one.”

The revolt is over a motion that ERG members say would effectively support removing a no-deal Brexit from the table, something they say would weaken the UK position.

Ex-Cabinet minister Nicky Morgan, a leading former Remain campaigner, backed the ERG’s criticism of the Government, saying it should have “taken time to discuss the wording of the motion with MPs on all sides... they would have achieved a clear and united signal”.