The Royal Women's Hospital in Melbourne is refusing to destroy several batches of frozen sperm in defiance of new state laws.

The hospital stores frozen sperm for individuals and couples who one day hope to have a baby.

But Victorian laws say samples must be destroyed after 10 years unless the owner applies for an extension.

The hospital has called for the State Government to amend laws.

Hospital spokeswoman Sarah White says it has had trouble contacting some donors and is retaining the sperm beyond the deadline.

"The problem is that these people are a mobile population," she said.

"These are young men who perhaps had sperm collected in their teens, they are now in their mid 20s, they are travelling overseas, they don't live with their parents anymore. There are just quite a few issues like that."

The hospital's medical advisor Dr Christine Bethal says they should be given extra time to apply for extensions.

"We respect the law but we think that's an unintended consequence of the law and we have not destroyed any semen without the express consent of the men whose semen is stored," she told ABC Local Radio.