Throughout each map, you'll encounter Rune stations that allow you to unlock a new Rune--each of which can enhance your abilities or enable new ones. You only have a limited number of Rune slots, so choose Runes that fit your playstyle or experiment with multiple combinations.

Slayer Strategy: : The Chrono Strike and Air Control Runes are a deadly combination for aerial attacks, while Seek and Destroy and Savagery are the perfect recipe for push-forward melee combat.