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Here’s what you need to know:

Deadly climax for Middle East protests

• At least 41 Palestinians were killed today and 1,700 others wounded after protests at the fence separating Gaza from Israel erupted again. The Israeli military said some in the crowds had been planting or hurling explosives.

Mass demonstrations at the fence began March 30, and dozens had already been killed. Our live briefing has the latest.

The violence comes as the U.S. formally relocates its embassy to Jerusalem from Tel Aviv, on the 70th anniversary of Israel’s declaration of independence.

Although Israel has arguably never been more powerful — militarily, economically or culturally — it remains estranged from its Arab neighbors. Our correspondent looks at the continuing tensions.