EAST RUTHERFORD, N.J. -- For the second straight preseason game, a New York Giants starter has gone down with an injury.

Safety Stevie Brown fell to the turf untouched during an interception return off Jets quarterback Geno Smith in the first quarter. He immediately clutched his left knee. Unable to put any weight on his left leg, Brown needed help to get to the sideline and locker room. The team announced Brown has a knee sprain and he did not return.

"I have no more further information," Tom Coughlin said. "I feel bad for Stevie. He has been a tremendous addition to our team. The guy has another interception and then has that happen."

Brown took to Twitter late Saturday night to give his thoughts on his injury.

I really appreciate all the thoughts and wishes, #StayingStrong and #Optimistic — Stevie Brown (@StevieBrown27) August 25, 2013

The Giants were already playing the Jets without starting safety Antrel Rolle, who is recovering from a sprained ankle. Rolle is expected to be ready for the season opener.

Jayron Hosley, the team's third-round draft choice in 2012, also left with a sprained ankle. Hosley is one of the Giants' second-string corners, along with Aaron Ross, and plays in some nickel and dime packages. He was also the team's primary punt returner in Saturday's game.

The Giants would like to be able to get to the opener against Dallas without any more injuries. In their second preseason game against the Colts, center David Baas and wide receiver Victor Cruz both suffered injuries on the opening drive. Baas suffered a left MCL injury that is being considered week to week and could potentially keep the starting center out past the opener.