A 61-year-old Belgrave man has been charged after police allegedly seized more than 2000 cannabis plants from several addresses in Melbourne's eastern suburbs on Wednesday morning.

Victoria Police Leading Senior Constable Paul Turner said Croydon Divisional Tasking Unit had charged Geoffrey Barnard with cultivating a large commercial quantity of cannabis, trafficking a large commercial quantity of cannabis and associated offences.

Police allegedly seized more than 2000 cannabis plants from a number of addresses in eastern Melbourne on Wednesday.

"Police executed a search warrant at a residential address in Wattle Avenue, Belgrave, about 6.50am," Leading Senior Constable Paul Turner said.

"Further warrants were executed at commercial properties at MacQuarie Place in Boronia, Dorset Road in Ferntree Gully and Power Road in Bayswater, allegedly locating sophisticated hydroponic operations containing large commercial quantities of cannabis plants and seedlings."

Leading Senior Constable Turner said police alleged that more than 2000 plants were seized in the raids.

Mr Barnard has been remanded to appear to Melbourne Magistrates Court on Thursday.