Music producer Suge Knight has been injured during a shooting at a glamourous awards show party in a Los Angeles nightclub hosted by singer Chris Brown, it has been reported.

Witnesses said 25-year-old singer, who is still on parole following his recent release from jail, had been the target of shots fired at the 1OAK club in West Hollywood, where he was hosting a pre-party for tonight's Video Music Awards.

Brown was thought to be unhurt, but three other victims - among them Death Row Records founder Marion 'Suge' Knight, 49, were reportedly taken to the city's Cedars Sinai hospital.

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Injured: Music producer Suge Knight (right) has been injured during a shooting at an awards show party at a Los Angeles nightclub hosted by singer Chris Brown (left) , it has been reported

Aftermath: Brown jumped on a table after the shooting, apparently furious at what had taken place

Chaos: Knight is treated by oparamedics after the frightening events at 1OAK in West Hollywood

Injured: Another victim is transferred into an ambulance in a stretcher

One of them was said to be in a critical condition.

Model and actor Tyson Beckford, and Black Eyed Peas member Apple de Ap were inside the pre-VMA party hosted by Brown and told TMZ they had heard four shots being fired at around 1.30am today.

Black Kapital Records CEO Knight was said to have walked out of the club, where he was spotted by a police officer and taken to hospital by ambulance.

He was reportedly shot twice, injuring his stomach and arm, and is now undergoing surgery.

The suspected gunmen were apprehended by police, as officers searched the nightspot for clues and quizzed revellers over the events of the night.

Roads around the nightclub were immediately sealed off by police, as the nightclub was evacuated, with several partygoers detained for questioning.

Angry: Brown at first appeared to still be furious when he made his way from the West Hollywood club

Leaving: Brown is seen walking to his Lamborghini after the drama at 1Oak in Los Angeles

OK now: Brown smiled as he left the nightclub where he was reportedly targeted by a gunman

Investigation: Roads around the nightclub were immediately sealed off by police, while officers questioned revellers over the shooting

Guests at the event had also included singer Justin Bieber and rapper The Game.

Katie Clendon, thought to have been inside the club, said via her Twitter account that she thought Brown had been the intended target.

'Literally can't believe what I just witnessed. Someone tried to fire shots at Chris Brown at 1oak. Speechless.'

She added: 'Prayers to all those harmed by this. Honestly still in disbelief this happened.'

In the moments after the shots were fired, Brown was seen climbing onto what appeared to be a bar in the nightclub, apparently angrily remonstrating with other clubgoers as a bouncer told partygoers to 'Get down'.

At around 5:45 a.m. LA time, Brown tweeted about the incident.

'It's disappointing that we as a society can#t have fun or enjoy ourselves without any altercations sometimes. Miss me with the bullsh*t!!!' he tweeted.

Witnesses: Partygoers talk to emergency personnel after the shooting

Treatment: Another victim is fitted with a neck brace following the dramatic shooting

Ambulance: Sirens rang out in busy West Hollywood after the Saturday night incident

Host: The pre-VMA party was hosted by Brown at the popular club in West Hollywood, pictured

Disappointing: Chris Brown took to Twitter in the early hours to express his disappointment at the shooting

Host: Brown enjoys the party before the alleged shooting took place

Night spot: Brown, who is still on parole following his recent jail sentence enjoys a drink with friends

Guests: Justin Bieber (right) was among the guests at the VMA Pre-Party hosted by Brown

Revellers: Rapper The Game (left) and musician Glass The Tramp (right) had also been at the party

Australian model Simone Holtznagel revealed she was at10AK's Pre-VMAs party when the shots were fired.

The former Australia's Next Top Model finalist took to social media to reveal she and fellow model friend Chloe Lloyd were within the vicinity, with Chloe also sharing the fact that the pair sought cover in a toilet cubicle when the incident occurred.

'Me and @MOANNN sort refuge in a toilet cubicle as rifles targeted Chris brown & bieber outside. #usa, (sic)' Chloe wrote on her Twitter account, tagging Simone in the social media post.

A controversial figure, Knight is no stranger to the effects of gun violence.

His friend Tupac Shakur was shot multiple times during a drive-by shooting in Las Vegas in September 1996, although during a previous visit to 1OAK in May, Knight told reporters that no one had ever been charged with Shakur's murder because he wasn't really dead, and was instead living on an island.

In the action: Australian model Simone Holtznagel said she hid in the bathroom during the drama

LA: The model referenced the differing gun laws in the USA and Australia, where firearms are banned

Knight also suffered a gunshot wound to the leg during a shooting at a 2005 pre-VMA party, hosted by rapper Kanye West.

Owned by New York-based Butter Group, the Los Angeles branch of 1OAK - which stands for One Of A Kind - is a spin off of the New York club, while there are further branches in Las Vegas and Mexico City.

The club, which bills itself as 'Bringing a New York nightclub experience to Los Angeles' has been open on the famous Sunset Strip since the start of the year and has proved popular with many celebrities, including Leonardo DiCaprio and Rihanna.

Last night's party at the club was a precursor to tonight's MTV Video Music Awards, which takes place from 6pm local time at LA's recently redeveloped Inglewood Forum.