You're at a party. Music is playing. Glasses are clinking. Dozens of conversations are driving up the decibel level. Yet amid all those distractions, you can zero in on the one conversation you want to hear.

This ability to hyper-focus on one stream of sound amid a cacophony of others is what researchers call the "cocktail-party effect." Now, scientists at the University of California in San Francisco have pinpointed where that sound-editing process occurs in the brain—in the auditory cortex just behind the ear, not in areas...