Republicans are breathing a sigh of relief after GOP Senate candidate Roy Moore’s defeat Tuesday in Alabama.

Moore’s loss will cut Senate Majority Leader Mitch McConnell Addison (Mitch) Mitchell McConnellPelosi: Trump hurrying to fill SCOTUS seat so he can repeal ObamaCare Senate GOP aims to confirm Trump court pick by Oct. 29: report Trump argues full Supreme Court needed to settle potential election disputes MORE’s (R-Ky.) already narrow two-seat majority down to just one next year.

That razor-thin 51-49 margin will leave GOP leadership with no room for error on top GOP agenda items — potentially including another run at repealing ObamaCare — and could put more pressure on them to negotiate with Democrats on run-of-the-mill bills and to break filibusters.

ADVERTISEMENT

But GOP senators said the slimmer majority is a small trade-off for avoiding long-term damage to the party caused if Moore had won Tuesday night’s special election and brought his sexual misconduct allegations and penchant for controversy to the Senate.

Sen. Richard Shelby Richard Craig ShelbySenate GOP eyes early exit Dems discussing government funding bill into February GOP short of votes on Trump's controversial Fed pick MORE (R-Ala.), who didn’t support Moore, said he and other Republicans were “relieved” after the former judge lost.

“I think it helps the Republicans in the long run that we won’t have someone who will be so radioactive, so controversial,” he said.

Shelby — speaking to a gaggle of reporters with Sen. Luther Strange Luther Johnson StrangeSessions hits back at Trump days ahead of Alabama Senate runoff The biggest political upsets of the decade State 'certificate of need' laws need to go MORE (R-Ala.) — added he was “conflicted” as he watched the election results because while Republicans would lose a Senate seat, he also felt “proud” that voters picked “principle over politics.”

Sens. Bob Corker Robert (Bob) Phillips CorkerHas Congress captured Russia policy? Tennessee primary battle turns nasty for Republicans Cheney clashes with Trump MORE (R-Tenn.) and Jeff Flake Jeffrey (Jeff) Lane FlakeJeff Flake: Republicans 'should hold the same position' on SCOTUS vacancy as 2016 Republican former Michigan governor says he's voting for Biden Maybe they just don't like cowboys: The president is successful, some just don't like his style MORE (R-Ariz.), both of whom are retiring after 2018, agreed that Moore’s loss was good for the long-term health of the party.

Flake — who tweeted out that “decency wins” in the immediate wake of the election results — added on Wednesday that it was a “good night.”

“You never like to lose a Republican seat here, but it never would have been worth the cost,” he said.

Corker said Moore’s loss was a “short-term setback” but added that the conservative candidate represented a “bridge too far” for the party.

“Was I happy for our nation? Yes. ... Ultimately this is probably really good for the Republican Party too,” he said.

Republicans have publicly grappled for weeks about what to do with Moore after several women came forward to accuse him of pursuing relationships with them when they were teenagers and he was in his 30s.

In a bombshell Washington Post report, Leigh Corfman said Moore initiated a sexual encounter with her when she was 14 years old and he was 32.

Senate Republicans, who were already lukewarm on Moore before the allegations, abandoned him in droves after the report and demanded that he drop out of the race.

But Moore, who has denied wrongdoing, remained defiant and lashed out against McConnell. The back-and-forth set up a showdown with GOP leadership that was expected to dominate the Capitol if he made it to Washington.

Underscoring their concerns, Republicans were expected to hold an emergency meeting on Wednesday morning to discuss a potential Ethics Committee investigation and if they would allow Moore to participate in Senate committees.

It’s not the first time McConnell has battled anti-establishment candidates. The GOP leader and his allies have been eager to prevent a repeat of 2010 and 2012, when some weak Tea Party candidates defeated rivals from the GOP establishment in primaries, only to lose general elections.

Senate Majority Whip John Cornyn John CornynThe Hill's Campaign Report: GOP set to ask SCOTUS to limit mail-in voting Liberal super PAC launches ads targeting vulnerable GOP senators over SCOTUS fight Senate GOP faces pivotal moment on pick for Supreme Court MORE (R-Texas) said the GOP loss in the deep red state should be a “wake-up call to everybody to make sure we nominate electable people”

“It’s nothing new. We’ve had this problem where people try to hijack the primary process and nominate people who can’t get elected in November,” he said.

GOP lawmakers were quick to knock Stephen Bannon, Trump’s former chief strategist, over his support for Moore and antagonism of establishment Republicans.

“Hopefully for Steve Bannon, he’ll realize that good candidates matter,” said Sen. Ron Johnson Ronald (Ron) Harold Johnson CIA found Putin 'probably directing' campaign against Biden: report This week: Supreme Court fight over Ginsburg's seat upends Congress's agenda GOP set to release controversial Biden report MORE (R-Wis.).

Asked what Tuesday night meant for Bannon’s influence, Shelby added: “I don’t think Steve Bannon had a good night.”

Republicans believe they are facing a good Senate map in 2018 as Democrats try to defend 26 seats, including 10 in states that Trump won in the presidential election. But Bannon, now the head of Breitbart News, has loomed over the midterm by threatening to primary every sitting GOP senator except Ted Cruz Rafael (Ted) Edward CruzTrump argues full Supreme Court needed to settle potential election disputes Press: Notorious RBG vs Notorious GOP The Hill's Morning Report - Sponsored by Facebook - Washington on edge amid SCOTUS vacancy MORE (Texas).

Rep. Pete King Peter (Pete) KingTrump holds private funeral service for brother Robert Trump at White House Cheney clashes with Trump Coronavirus Report: The Hill's Steve Clemons interviews Rep. Sean Patrick Maloney MORE (N.Y.) said it was time for the GOP to “dump” Bannon, adding that he “does not belong on the national stage.”

“He looks like some disheveled drunk that wandered onto the political stage,” King told CNN’s “New Day.”

And Rep. Mike Simpson MIchael (Mike) Keith SimpsonDuring a time of uncertainty, Great American Outdoors Act deserves our support Dentists want coronavirus testing kits before reopening MLB, Congress play hardball in fight over minor leagues MORE (R-Idaho), while saying Moore’s loss was better for his party, estimated that there’s a “50-50” chance that his party could be in the House minority next year.

“It feels like 2006 and a little bit like 2010. I say that because I look at retirements. And you saw the same thing in 2006, and you saw the same thing in 2010,” Simpson said.

Democrats immediately seized on the win in Alabama to demand that Republicans delay a vote on their tax bill until Jones is sworn in later this month or in early January.

But there’s no sign Republicans will acquiesce to the demand, or that Democrats will be able to win over the three GOP senators needed to kill or delay the tax bill.

Sen. Dick Durbin Richard (Dick) Joseph DurbinTumultuous court battle upends fight for Senate McConnell focuses on confirming judicial nominees with COVID-19 talks stalled Senate Republicans signal openness to working with Biden MORE (Ill.), the No. 2 Senate Democrat, said he hoped, more broadly, that Senate Republicans would show “more independence” starting in 2018 after watching a candidate Trump supported lose.

“There’s nothing that concentrates the mind more than the thought that you might lose the next election,” he said.

But Republicans were quick to downplay the impact of losing the Alabama Senate seat, disputing the idea that it marked the death knell for the GOP agenda.

Sen. Roy Blunt Roy Dean BluntSocial media platforms put muscle into National Voter Registration Day Senate GOP faces pivotal moment on pick for Supreme Court This week: Supreme Court fight over Ginsburg's seat upends Congress's agenda MORE (R-Mo.) claimed that slimmer majorities could be easier to manage.

“When I was the whip in the House, the easiest whipping we ever had was when we had the smallest majority we ever had,” Blunt said.

Sen. Thom Tillis Thomas (Thom) Roland TillisThe Hill's Campaign Report: GOP set to ask SCOTUS to limit mail-in voting OVERNIGHT ENERGY: EPA head questions connection of climate change to natural disasters | Pebble Mine executives eye future expansion in recorded conversations | EPA questions science linking widely used pesticide to brain damage in children Liberal super PAC launches ads targeting vulnerable GOP senators over SCOTUS fight MORE (R-N.C.) added that the agenda “doesn’t really change” and that having 51 instead of 52 seats would only “be material” for a handful of nominations or if Republicans again used reconciliation to pass bills.

To overcome a 60-vote procedural hurdle on legislation, Republicans already need help from at least eight Democrats, if their own caucus remains united. And under reconciliation, the budget rules that allow them to avoid a filibuster, Republicans have to walk a narrow path that empowers a small fraction of senators.

“The Republican caucus … is more entrepreneurial, OK? I mean, every now and then we have a free-range chicken that kind of goes out on its own. And before, we could lose two of those chickens and now we can only lose one,” said Sen. John Kennedy John Neely KennedyMORE (R-La.).

Kennedy added that “it will make it harder, but it’s not like it was easier before.”

Republicans have struggled to score legislative victories despite having the first unified GOP government in roughly a decade.

The push to repeal ObamaCare in July was killed after GOP Sens. Susan Collins Susan Margaret CollinsSenate GOP aims to confirm Trump court pick by Oct. 29: report The Hill's Campaign Report: GOP set to ask SCOTUS to limit mail-in voting Senate GOP sees early Supreme Court vote as political booster shot MORE (Maine), Lisa Murkowski Lisa Ann MurkowskiSenate GOP aims to confirm Trump court pick by Oct. 29: report Senate GOP sees early Supreme Court vote as political booster shot Pence defends Trump's 'obligation' to nominate new Supreme Court justice MORE (Alaska) and John McCain John Sidney McCainCindy McCain endorses Biden: He's only candidate 'who stands up for our values' Biden says Cindy McCain will endorse him Biden's six best bets in 2016 Trump states MORE (Ariz.) joined together to kill the “skinny” repeal legislation.

“I give the Alabama voters a lot credit for rejecting Roy Moore’s candidacy,” Collins said on Wednesday.

Asked if the 51-49 margin will empower moderates, Collins said: “Let’s hope so.”