Hobart police are still trying to find two men wanted in connection to a shooting on Saturday night at a cocktail bar where more than 10 rounds were fired into a closed door.

A high-powered rifle was used at Pablo's Cocktails and Dreams in the city centre, in what police say was a targeted attack.

About 20 people were in the bar at the time of the shooting just after midnight.

Police said patrons were shaken and it was lucky no-one was hurt.

Two men approached the bar about midnight and multiple shots were fired through the main door, which had just been closed for the night.

Inspector Adrian Bodnar said a patrol car was nearby and officers were on the scene within 60 seconds of the first report.

Pablo's Cocktails and Dreams is less than a block away from Night Mass, one of the Dark Mofo festival sites. ( ABC News )

'Some of the people there were quite shaken, thankfully nobody there was injured because this had the potential to be a really nasty incident," he said.

He would not disclose details about the weapon, the exact number of shots fired or whether it was an illegal firearm.

"For operational and investigative reasons I can't disclose any further information about the type of firearm other than saying it was a high-powered weapon," he said.

Sorry, this video has expired Police say the incident was not random and they are "following a particular line of inquiry".

"I don't want to release any information that may hamper or impede the investigations."

Police are reviewing CCTV footage from nearby premises and have witness statements from several people in the area.

The men fled on foot behind the premises and headed north. A firearm and ammunition were found nearby.

No-one was injured in the incident, which occurred a little after midnight. ( ABC News: Scott Ross )

The gunman is described as about 40 years old, with red facial hair and about 170 centimetres tall, with a thick-set build.

He was wearing a long sleeve black top, black tradies trousers and black boots.

No description of the second offender is available.

Byron Bay visitor Colleen Crawford also thought the noise was related to Night Mass. ( ABC News )

Police said their investigations so far suggested the incident was not random and they were following several lines of inquiry.

The bar is less than a block away from one of the major sites for the Dark Mofo winter festival, Night Mass, in Liverpool Street.

Thousands of people attended Saturday night's event, which started at 10:00pm.

New Zealand tourist Rigel Walsh was walking back from Salamanca about 12:10 am and heard shots being fired.

"We heard four loud bangs, it sounded to me like gunshots we've a bit of experience with firearms," he said.

"I didn't see anyone run out, it sounded like it came out of the Night Mass … I thought it must have been something pyrotechnic or something like that."

Mr Walsh said moments before he had considered going to the bar.

"We looked down the alleyway and the door was open but we decided we'd rather go to bed, a lucky choice obviously.

"I guess one of those lucky serendipitous moments of life."

Officers inspect the area behind Pablo's Cocktails and Dreams in central Hobart. ( ABC News: Scott Ross )

Colleen Crawford from Byron Bay also heard the shots and dismissed them as festival noise.

"It did sound like gunshots but I thought it could just have been part of the revelry," she said.

"I wasn't frightened because I simply thought it was fireworks or something going off, but it did get me to the point where I actually got up and had a look."

The bar's Facebook page says it is a speakeasy 1920s-inspired venue which was founded last September.

Anyone with information is urged to contact police or CrimeStoppers.

Following the incident, the Tasmanian Government would not be drawn on its proposal to weaken the state's gun laws.

The Government plans to give farmers and sporting shooters easier access to some previously-restricted firearms.

Police have expressed concern that the plan could breach the National Firearms Agreement.

Deputy Premier Jeremy Rockliff said on Sunday he would not comment on a police investigation.

The proposal will be the subject of an upper house inquiry later this year.