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A Brooklyn couple was killed when a fire engulfed their house early Monday — as their 17-year-old daughter escaped the flames by jumping out a first-floor window, officials and neighbors said.

The blaze erupted on the first floor of Howard and Evelyn Gluck’s two-story, wood-framed house on 44th Street near 12th Avenue in Borough Park just before 4 a.m., fire officials said.

Howard, 61, and Evelyn, 59, were discovered unconscious in the rear of the home and died at a nearby hospital.

A neighbor, Maurine Weiner, said she was awakened by the cries of the couple’s daughter.

“I heard screaming. I thought someone was being attacked. I was about to call 911,” she recalled.

“Then my granddaughter came to my door and said, ‘Quick, there’s a fire next door. We gotta get out of here,’ ” Weiner added.

The neighbor said the Glucks had lived in the house for more than 40 years and were preparing for their daughter’s upcoming wedding.