Four people were rushed to the hospital in critical condition, one with life threatening injuries, after a shooting in the heart of the downtown tourist and convention district overnight, News Radio 1200 WOAI reports.

Police say the incident began shortly before midnight with a road rage incident, where drivers of a white pickup and a blue sedan traded insults at East Market Street and Tower of the Americas Way, which is a block away from the Henry B. Gonzalez Convention Center and in the shadow of the city's iconic Tower of the Americas.

A man in the pickup pulled a handgun and emptied it into the sedan.

The driver of the car was shot at least three times, and he was rushed to SAAMC with life threatening wounds. He was reported to be on life support at last check.

Three other men in the car were shot, one man was shot in the back and the other in the neck. Both are in critical condition at University Hospital.

A woman in the car avoided injury and is being interviewed by police.

The white pickup sped away and remains at large.