A "targeted" shooting at a Melbourne home with five people inside was followed by a violent car chase through suburban streets, as the offenders attempted to shoot at vehicles and pedestrians who tried to stop them escaping.

Detectives have launched an appeal for information four months after the incident on Providence Place in Rowville on March 3, just after 1am.

Police are appealing for public information about these vehicles. Credit:Victoria Police

Police believe a man in a white Mazda van, which had been stolen hours before, got out and fired five shots into the home.

Five people were home at the time: two parents, their two adult children and one of the children's partners.