The Sydney Sixers will await an assessment on Ellyse Perry to determine the severity of what appears to be a shoulder injury suffered against the Melbourne Renegades.

The Australian all-rounder looked to be in severe pain after trying to take a catch on the boundary, as she landed heavily on her right shoulder.

She could then be seen wincing in agony after another fielding attempt in the over after the incident occurred.

The injury scare comes just weeks out from the Sixers' finals campaign, which will commence on December 7th, while Australia's T20 World Cup begins in March.

This is worrying. Ellyse Perry has landed heavily on her shoulder, and appears to be in a great deal of pain...#WBBL05 pic.twitter.com/6AuCsyC7SC — #7Cricket (@7Cricket) November 17, 2019

Perry helped set up a run chase of 139 for the Sixers with the bat, after she contributed 37 off 45 balls.

Whilst she didn't take a wicket, she had the Renegades on the back foot, conceding just 14 runs off her three overs bowled prior to succumbing to the cruel injury.

However, the 29-year-old was unable to bowl again after the shoulder knock.

With Perry sitting helplessly in the field with two overs remaining in the match, the Renegades took 29 runs, with Courtney Webb smashing a six off the last ball of the game to help secure a stunning victory for her side at Drummoyne Oval.

It handed the Sixers just their second loss of the season, adding further salt to the wound as the Sixers await the diagnosis for Perry's injury.