A man burst into a Queens nail salon where his wife was working on Wednesday evening and stabbed her to death, cops said.

The suspect, 39, walked into the Tu S’tilo Salon SPA 37th Avenue near 93rd Street in Jackson Heights at about 7 p.m. and stabbed his 35-year-old wife, identified on her Facebook page and by police sources as Iris Rodriguez, several times with a knife, police said.

Medics responded and took the woman, 35, to Elmhurst General Hospital where she was pronounced dead.

Police arrested the suspect at the scene.

He was injured during the attack and taken to the same hospital, where he remained as of Thursday morning, cops said.

The couple has no history of domestic incidents with the NYPD, a police source said. Charges against the suspect — who has never been arrested by the police department — were pending.

Additional reporting by Stephanie Pagones