No, it's not safe. First of all, just taking 6 10/500's alone could seriously damage your liver. The maximum DAILY dose of acetaminophen is 4 grams. You would be taking 3 grams in one shot. That alone would do a serious number on you, but combine that with alcohol and your low bodyweight, and liver damage becomes very likely.

Also, 60mg of oxycodone could very well be too much for your body to handle even as a habitual opiate user. I know you have previous experience with opiates, but you cannot reliably predict what your tolerance will be like with oxycodone if you are not a regular user of that particular drug.

Assuming your liver makes it, potentially fatal respiratory depression is also very likely just from 60mg if it is too much for your body. Add alcohol, and again, the chances go way up. You could also pass out, vomit and asphyxiate. Wouldn't that be a great way for your loved ones to find you?

If you insist on taking these, I would suggest you do a cold water extraction (google it) to get rid of the Tylenol, and don't pop 60 mg your first time. The few times I have done these, 10-15mg produced a nice buzz for me, a non-regular opiate user with no tolerance, and I am 235 pounds. You may not get the buzz you want, but would you rather go into a coma because you were greedy? This is why drug addicts die - they cannot stand to "waste" their drugs by getting anything less than the desired effect.

I would also not take any alcohol with these no matter how much you take, because really, you are increasing the risk by a huge amount for very little reward. Oxycodone is nice enough on its own without boosting it with other substances. If you must do something else, smoke a little (keyword a little) pot.

Long story short, there is no clear line between "you will die" and "you will not die" when it comes to drug use, but by taking 60mg of oxy, 3 grams of tylenol, and finishing it off with alcohol, you are putting yourself into "serious risk of death or permanent damage" territory.

Please use your head here.