Description

Buy Januvia 100mg Online

JANUVIA is a once-daily prescription pill that is part of a class of medicines called DPP-4 inhibitors. JANUVIA, along with diet and exercise, helps lower your blood sugar (A1C).

JANUVIA works when your blood sugar is high, and works less when your blood sugar is low, because it works by enhancing your body’s own ability to lower blood sugar.

While you may be aware that your blood sugar shouldn’t go too high, you also need to be careful that it doesn’t go too low. When your blood sugar goes too low, this is known as hypoglycemia

How should Januvia be taken?

You should take your Januvia tablets 100mg once daily, with a glass of water and with or without food. You may be taking Januvia 100 in combination with other antidiabetic drugs which you should take according to your doctor’s recommendations. You will be given a diet and exercise programme to follow as well as your medication. You should continue to take your Januvia tablets 100mg along with your other medication and a healthy diet and exercise programme for as long as recommend by your doctor, which may be for long-term to maintain your blood sugar levels.

When should Januvia not be used?

You should not use Januvia tablets 100mg if you:

are allergic to sitagliptin or any ingredients in Januvia

have type 1 diabetes or diabetic ketoacidosis

have symptoms of pancreatitis while taking Januvia, including severe persistent stomach pain, with or without vomiting

are pregnant or are breastfeeding

have severe kidney disease

are taking medicines that interact with Januvia: digoxin for heart failure is slightly affected by sitagliptin

Dosage & Administration

Recommended Dosing

The recommended dose of JANUVIA is 100 mg once daily. JANUVIA can be taken with or without food.

Patients With Renal Insufficiency

For patients with mild renal insufficiency (creatinine clearance [CrCl] greater than or equal to 50 mL/min, approximately corresponding to serum creatinine levels of less than or equal to 1.7 mg/dL in men and less than or equal to 1.5 mg/dL in women), no dosage adjustment for JANUVIA is required.

For patients with moderate renal insufficiency (CrCl greater than or equal to 30 to less than 50 mL/min, approximately corresponding to serum creatinine levels of greater than 1.7 to less than or equal to 3.0 mg/dL in men and greater than 1.5 to less than or equal to 2.5 mg/dL in women), the dose of JANUVIA is 50 mg once daily.

For patients with severe renal insufficiency (CrCl less than 30 mL/min, approximately corresponding to serum creatinine levels of greater than 3.0 mg/dL in men and greater than 2.5 mg/dL in women) or with end-stage renal disease (ESRD) requiring hemodialysis or peritoneal dialysis, the dose of JANUVIA is 25 mg once daily. JANUVIA may be administered without regard to the timing of dialysis.

Because there is a need for dosage adjustment based upon renal function, assessment of renal function is recommended prior to initiation of JANUVIA and periodically thereafter. Creatinine clearance can be estimated from serum creatinine using the Cockcroft-Gault formula. [See CLINICAL PHARMACOLOGY] There have been postmarketing reports of worsening renal function in patients with renal insufficiency, some of whom were prescribed inappropriate doses of sitagliptin.

Concomitant Use With An Insulin Secretagogue (e.g., Sulfonylurea) Or With Insulin

When JANUVIA is used in combination with an insulin secretagogue (e.g., sulfonylurea) or with insulin, a lower dose of the insulin secretagogue or insulin may be required to reduce the risk of hypoglycemia.

Expert Advice

Januvia helps to control high blood sugar level and avoid long-term complications of diabetes.

Januvia can be taken with or without food.

Monitor your blood sugar regularly.

Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines.

Inform your doctor immediately if you have severe stomach pain, nausea, and/or vomiting. These could be symptoms of pancreatitis.

Inform your doctor immediately if you have severe joint pain.

Drugs Interact

Drugs that interact with Sitagliptin Phosphate include the following:

Bexarotene

Ethanol

Gatifloxacin

Ivacaftor

Side Effects

The most commonly reported side effects when taking Januvia tablets 100mg, depend on whether you are taking Januvia alone or with another drug. They include: gastrointestinal upset (nausea, diarrhoea, indigestion, flatulence, vomiting)

headache,

upper respiratory infection,

stuffy or runny nose and

sore throat, cough,

fungal skin infection,

peripheral oedema (swelling of the hands or leg).

Hypoglycaemia (low blood sugar) can occur when Januvia is used in combination with a sulfonylurea medicine.

Frequently Asked Questions

Should I follow any special dietary instructions while taking Sitagliptin Phosphate?

Avoid consumption of alcohol while taking Sitagliptin Phosphate tablet, as it may worsen the side effects of the drug.

Is it safe to alter the dose of Sitagliptin Phosphate?

Do not change the dose of Sitagliptin Phosphate tablet without consulting the doctor. Altering the dose of the drug may increase the risk of side effects.

Do I need to be monitored for any laboratory parameters while taking Sitagliptin Phosphate?

A regular monitoring of your blood sugar levels is advised while using Sitagliptin Phosphate tablet.

Can I use Sitagliptin Phosphate tablet to treat type 1 diabetes?

Sitagliptin Phosphate tablet is not prescribed for patients who have type 1 diabetes. Please consult your doctor.

Uses

Januvia 100mg Tablet is used in the treatment of type 2 diabetes

It is used in addition to diet and exercise to improve blood sugar control in adults with type 2 diabetes.