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Investors have dumped stock in Germany's largest bank, taking its price down almost one per cent today, and by more than three per cent over the the last five trading sessions.



Deutsche has already lost almost half its value this year, as markets fret over the bank's weakness and a looming fine from US authorities.



The troubled lender is now looking vulnerable to shocks set to rip through the eurozone if Italy's Prime Minister loses a vote over Constitutional Reform on Sunday, said experts.



It's feared Italy's banking sector could topple if leader Matteo Renzi is forced to resign.

GETTY Investors are selling-off Deutsche Bank

GETTY Renzi could lose the referendum over Constitutional change on Sunday

Contagion could then spread through to some of Europe's most systematically important banks, such as Deutsche, which already look fragile, experts warned.



As a result, the referendum has caused markets to question whether the German government would step in and save Deutsche, should it need help.



Similar worries surfaced earlier this year, after comments from Angela Merkel confirmed she would not approve a state-backed rescue of banks.



This year Deutsche has sold assets and axed jobs, as part of a huge cost-cutting programme aimed at shoring up its position.



But investors are not convinced it is enough to stabilise the bank.

The many faces of Angela Merkel Wed, May 17, 2017 German Chancellor, Angela Merkel through the years Play slideshow 1 of 16

Yahoo Deutsche's share price has fallen by 40% in a year