This cat-and-mouse game turned into a full-fledged Times Square brawl.

Costumed hustlers dressed as Hello Kitty and Minnie Mouse bared their claws while fighting over a tip Thursday — and ended up in cuffs.

The fur flew after the two posed together with some passers-by, and the Hello Kitty “performer” — Jiovanna Melendez, 40 — ­allegedly wouldn’t share the resulting tip with Minnie Mouse Sandra Mocha, 34.

Even a faux Spider-Man swung into action, but the ersatz webslinger couldn’t break them apart as they slapped, scratched and punched each other.

“I tried to stop them, but they were hysterical,” said Spidey, who on Friday would only identify himself as — you guessed it — “Peter Parker.”

Cops tried to cool things down, but the women insisted on pressing charges, Spider-Man recalled.

Tourists on Friday were disappointed they missed the action.

“I would definitely have tipped extra,” said Anthony Jacobi-Dolce, 23, of Chicago. “And I would bet on Minnie to win because I don’t even know what Hello Kitty is.”

By the sight of them in Manhattan Criminal Court, Minnie Mouse got the upper paw: Hello Kitty sported a sizable scratch on her face.

That didn’t surprise Times Square tourist Malachi Cornelius, 10, from Evanston, Ill.

“The mouse always outsmarts the cat,” he said.

Additional reporting by Natasha Velez and Laura Italiano