The Denver Broncos have started the season 4-0, look nearly unbeatable, and have quarterback Peyton Manning operating at a record pace. The Jacksonville Jaguars are 0-4, have lost by an average of nearly 25 points a game, and have the opposite of Peyton Manning at quarterback.

Those two teams meet in Week 6, and Las Vegas is expecting it to get ugly.

Vegas consensus is that the Broncos will be a 28-point favorite over the Jaguars, biggest spread in NFL history, says @RJInVegas. — darren rovell (@darrenrovell) September 30, 2013

The sad thing is, even with a 28-point spread there probably won't be very many people riding the Jaguars.