(CNN) The Democratic Republic of Congo has reached a grim new milestone in the Ebola outbreak that began August 1: The total number of probable patients is 608 as of Wednesday, with 368 deaths, the Ministry of Health said. An additional 29 people who doctors suspect may be sick with Ebola are under investigation. The ministry also reported that 207 people have recovered from the life-threatening illness.

On average, Ebola -- which causes fever, severe headache and in some cases hemorrhaging -- kills about half of those infected, but fatality rates in individual outbreaks have varied. The latest outbreak has a case fatality rate of about 60%.

The outbreak is the second-deadliest and second-largest in history, topped only by one in West Africa in 2014, when the disease killed more than 11,000 people, according to the World Health Organization.

Those intimately affected include health care workers, some of whom have traveled to the region from other nations. An American who was providing medical assistance in Congo experienced a possible exposure to the Ebola virus and is being monitored for symptoms in the United States, according to a statement from the Nebraska Medical Center on Saturday. The medical center did not disclose the person's identity due to privacy concerns.

North Kivu province, which includes the cities of Beni, Kalunguta and Mabalako, remains the epicenter of the outbreak, though cases have been reported in neighboring Ituri province, according to the World Health Organization. The two provinces are among the most populous in the nation and border Uganda, Rwanda and South Sudan.

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