In "Dark City" (1998), all of the human memories are newly fabricated when the hands of the clock reach 12. This is defined as "midnight," but the term is deceptive, because there is no noon. "First came darkness, then came the Strangers," we are told in the opening narration. In the beginning, there was no light. John Murdoch, the hero, asks Bumstead, the police detective: "When was the last time you remember doing something during the day?" Bumstead is surprised by the question. "You know something?" Murdoch asks him. "I don't think the sun even exists in this place. I've been up for hours and hours, and the night never ends here."

The narration explains that the Strangers came from another galaxy and collected a group of humans to study them. Their civilization is dying. They seek to find the secret of the human heart, or soul, or whatever it is that falls outside their compass. They create a vast artificial city, which can be fabricated, or "tuned," whenever they want to run another experiment.

We see the tuning taking place. All humans lose consciousness. All machinery stops. Changes are made in the city. Skyscrapers are extruded from the primordial materials of the underworld, architecture is devised, rooms are prepared for their inhabitants, props are set in place. Aided by a human scientist, the Strangers inject memories into the foreheads of their test subjects. When humans awaken, they have no memory of the day before; everything they remember has been injected from a communal memory bank. If a man commits murder one day and then is given a new identity, is he still capable of committing murder? Are men inherently good or evil, or is it a matter of how they think of themselves? The Strangers need to know.

Murdoch (Rufus Sewell) has developed an immunity to the devices of the Strangers. His latest memory injection was incomplete. It was administered by Dr. Schreber (Kiefer Sutherland), a scientist who works for the Strangers but has no love for them. Murdoch wakes in a hotel room with the corpse of a dead woman; the script for the day has made him a serial killer of prostitutes. Schreber warns him he is the subject of an experiment but has proven resistant to it. The Strangers are coming for him, and he must flee.