“…doing nothing is not an option. The stakes are enormous …”

Opinion: Addressing systemic problems in the biomedical research enterprise, PNAS, 2/17/2015

This website is a platform to discuss solutions to problems such as those addressed in the April 2014 PNAS article entitled Rescuing US biomedical research from its systemic flaws, as outlined here. Overseen by a Steering Committee that includes Nancy Andrews, Prachee Avasthi, Jeremy Berg, Mary Sue Coleman, Daniel Colón-Ramos, Ron Daniels, Kafui Dzirasa, Rush Holt, Freeman Hrabowski, Tony Hyman, Story Landis, Gary McDowell, Erin O’Shea, Roderic Pettigrew, Jessica Polka, Joan Reede, Keith Yamamoto, Elias Zerhouni and director Chris Pickett — in addition to ourselves, the website seeks to organize and prioritize the suggestions, data and outcomes from an ongoing series of relevant publications, workshops and experiments. Our aim is to help the United States make continual progress against the various logistical, administrative and conceptual logjams that have prevented the implementation of effective solutions to the major problems that we and many others have identified.

Thank you for your willingness to contribute to this important effort,

Bruce Alberts, Judith Kimble, Shirley Tilghman, Harold Varmus

Photo: Arda Mizrak, Augie Seone, and Karen Ruiz in Dr. David Morgan’s lab at the University of California, San Francisco. Photo by Yolanda O’Bannon, April 2015.