Grammy-winning singer John Prine, who wrote his early songs in his head while delivering mail and later emerged from Chicago's folk revival scene in the 1970s to become one of the most influential songwriters of his generation, died on Tuesday. He was 73.

Prine was hospitalized in Nashville on March 26 suffering from symptoms of COVID-19, the respiratory disease caused by the novel coronavirus, according to his wife, Fiona Whelan Prine, who was also his manager.

"We join the world in mourning the passing of revered country and folk singer/songwriter John Prine," the Recording Academy said in a written statement.

"Widely lauded as one of the most influential songwriters of his generation, John's impact will continue to inspire musicians for years to come. We send our deepest condolences to his loved ones."

A publicist for Prine confirmed his death due to complications from COVID-19 at Vanderbilt University Medical Center in his adopted hometown of Nashville.

Born in Chicago on October 10, 1946, to William Prine and Verna Hamm, both originally of Kentucky, Prine was taught by his older brother David to play guitar at the age of 14 and attended music classes at the Old Town School of Folk Music.

After graduating from high school in suburban Maywood, Illinois, Prine worked as a mail carrier for five years, performing in Chicago clubs in the evenings at occasional "open mic" nights.