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WATCH ABOVE: Police believe speed was a factor in a single-vehicle collision that killed a 47-year-old man Saturday.

EDMONTON — Police believe speed was a factor in a collision that killed a 47-year-old man Saturday afternoon.

Police responded to a single-vehicle collision on Anthony Henday Drive at 101 Avenue around 12:15 p.m. Saturday.

Officer say a Dodge Ram 1500 pickup truck was heading south on Anthony Henday Drive when it veered off the road into the centre boulevard and struck an overhead sign. The vehicle stopped along the west shoulder of Anthony Henday Drive northbound, 300 metres north of Stony Plain Road.

Officers say the 47-year-old man driving the truck was declared dead at the scene. Police say he was not wearing a seatbelt. He was the only person in the vehicle at the time of the crash.

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Police believe speed played a role in the crash. The EPS Major Collision Investigation Unit is investigating.

The Henday between Stony Plain Road and 111 Avenue was completely shut down to traffic early Saturday afternoon. The roadway was reopened in both directions by 5 p.m.

It’s been a deadly couple of days on Edmonton streets. Two people were killed in two separate collisions Friday morning.

A 55-year-old motorcyclist was killed following a collision in the area of 62 Avenue and Callingwood Road Friday morning. Police say the motorcyclist was making a left turn onto Anthony Henday south when he was struck by an SUV coming from the opposite direction.

Earlier Friday morning, police were called to the area of 178 Street and 118 Avenue after a pickup truck slammed into a building. A 48-year-old man was found dead inside the truck. Police say it’s not yet known what caused the driver to crash into the building.

“We’ve seen a startling number of traffic fatalities in the past few weeks in our city. It’s a concern to both police and citizens,” said Sgt. Alvarado with the EPS Major Collision Investigation Unit.

“We’re reminding Edmontonians to make safe driving decisions every time you’re behind the wheel – drive defensively, wear a seatbelt, never drive impaired and don’t speed. This applies in all road conditions.”

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Saturday’s collision in the west end is Edmonton’s 16th traffic fatality of 2015.