Bonnie MacLean, whose colorful posters for rock shows in San Francisco in the 1960s and early ’70s helped define the psychedelic scene and have since become collector’s items, died on Feb. 4 in Newtown, Pa. She was 80.

Her son, David Graham, said Ms. MacLean, who moved to Bucks County, Pa., in the 1970s, died at a nursing home. He did not specify the cause.

Ms. MacLean was married to the famed concert promoter Bill Graham as he was beginning his career in the mid-1960s in San Francisco, where she was immersed in a vibrant cultural scene that generated influential groups like Jefferson Airplane and the Grateful Dead. She worked with him mounting shows — most of them at the Fillmore Auditorium — which he promoted with attention-getting posters commissioned from several artists.

A group of men became known as the Big Five of poster art: Wes Wilson (who died last month), Victor Moscoso, Rick Griffin, Stanley Miller (known as Stanley Mouse) and Alton Kelley. Ms. MacLean wasn’t initially part of the group; when Mr. Wilson and Mr. Graham had a falling-out in 1967, she stepped in to fill the void.