In the northern province of Aleppo, US- and Turkish-backed rebels have seized the town of Al-Rai, the jihadist group's main entry point from Turkey.

The jihadists have suffered a series of setbacks in Syria in recent weeks, losing the ancient city of Palmyra and the IS bastion of Al-Qaryatain, both in the central province of Homs, to Russian-backed government forces.

"The three sides are racing to grab as much of the pie as possible, not just at the expense of the Islamic State group but also ... from other key players," said Thomas Pierret, a Syria expert at the University of Edinburgh.

The scramble by the regime, anti-government rebels and Kurdish militia to recapture areas from IS has been given added urgency by the prospect of a possible federal system.

The Islamic State group is under growing pressure on several fronts in Syria as rival forces battle to wrest territory from the jihadists, who are excluded from a six-week-old ceasefire.

The jihadists have suffered a series of setbacks in Syria in recent weeks, losing the ancient city of Palmyra and the IS bastion of Al-Qaryatain, (pictured) both in the central province of Homs, to Russian-backed government forces (photo by: Max Delany/AFP/File)

In the south, meanwhile, rival jihadists from the Al-Qaeda-affiliated Al-Nusra Front and their rebel allies have captured three towns from IS.

And in the northeast, the mainly Kurdish Syrian Democratic Forces are pressing an advance towards the oil-rich province of Deir Ezzor, which the regime also has its sights set on.

Sharing the pie

With a new round of peace talks due to get under way in Geneva on April 13, experts say the scramble for territory has taken on increasing importance.

When the regime recaptured

Palmyra, "it understood the diplomatic advantage it would gain in negotiations" with the opposition, Pierret said.

Rebels trying to advance along the Turkish border meanwhile have twin aims -- pushing back IS and preventing Kurdish militias from expanding their territory, he said.

"For the moment, the pie is big enough for everyone" fighting IS, Pierret added.

Displaced Syrians wait in the central Syrian city of Homs for buses made available by the government to take them back to their homes in the town of Palmyra (photo by: Louai Beshara/AFP)

"The coming stages will be more complicated: to the east of Aleppo, there are areas that the regime, the Kurds and the rebels are interested in controlling."

It is easy to see the allure of IS-held turf -- which covers about 40 percent of Syria, and is rich in oil, gas and agricultural wealth.

But with every victory over IS, there is a growing risk of renewed confrontation between non-jihadist rebels and the regime, who have observed a fragile ceasefire since February 27.

"I don't think the Russians and the Americans will be able to stop their allies from fighting each other forever," said Romain Caillet, a French expert on jihadist movements.

The truce brokered by Washington and Moscow has brought a lull in clashes between the regime and non-jihadist rebels.

In the unlikely event that the jihadists' enemies continue to refrain from fighting each other, the recapture of IS territory "will see the organisation return to totally clandestine activity", Caillet said.

Raqa, the prize

Image taken from footage on the Russian Defence Ministry website purporting to show airstrikes by the Russian air force on an Islamic State facility in the Syrian province of Deir Ezzor (photo by: RUSSIAN DEFENCE MINISTRY/AFP/File)

Syria's regime and opposition categorically rejected a Kurdish declaration in March of a federal region in areas under their control in the country's north.

But their backers Russia

and the United States are not opposed to such a plan, according to Fabrice Balance, a visiting fellow at the Washington Institute.

"The United States and Russia seem to agree on federalism for Syria," the Syria expert said.

"One way to weaken Assad is to agree on the distribution of zones of influence."

With IS on the defensive, the big question now is: who will be the first to recapture IS's de facto Syrian capital Raqa?

A diplomat from a European nation participating in the US-led anti-IS coalition said there would be consequences for the opposition and its Western supporters if Russian-backed regime forces seize the jihadist stronghold.

"If the Russians and the regime do take Raqa, we do consider it will be a critical step. It will prove that they have won the war, to be frank, and that the opposition is only a small pocket in the north," the diplomat said.