A large-scale underground network of concealed tunnels and rooms have been uncovered during police raids in Queensland's Darling Downs.

Police officers arrested 59 people on 180 drug offences charges after executing 46 warrants as part of Operation Oscar Glyph, aimed at disrupting the distribution and sale of dangerous drugs.

A high quality and complex water filtration system, a number of illegal firearms, knuckle dusters and knives, a quantity of chemicals and equipment used for the manufacture of ice and cannabis were also located during the raids.

It will be further alleged during the search of residences police located more than a kilogram of cannabis, 200 cannabis plants, seven native pythons being kept without licenses, a quantity of cash obtained from the sale of ice and 20 grams of ice.

Acting Senior Sergeant Mick Loveday said police would continue to arrest and prosecute anyone involved in the drug trafficking industry.

"The information utilised by police was obtained from the tenacious efforts of Toowoomba police as well as the vigilant and informative members of the community," he said.

The 59 people charged will face Toowoomba Magistrates court early August.