David Foster Wallace, whose darkly ironic novels, essays and short stories garnered him a large following and made him one of the most influential writers of his generation, was found dead in his California home on Friday, after apparently committing suicide, the authorities said.

Mr. Wallace, 46, best known for his sprawling 1,079-page novel “Infinite Jest,” was discovered by his wife, Karen Green, who returned home to find that he had hanged himself, a spokesman for the Claremont, Calif., police said Saturday evening.

Mr. Wallace was a professor in the English department at Pomona College in Claremont.

“I know a great novelist has left the scene, but we knew him as a great teacher who cared deeply about his students, who treasured him. That’s what we’re going to miss,” said Gary Kates, the dean of Pomona College.

Mr. Wallace had taught at the small liberal arts college since 2002 and held the school’s Roy Edward Disney Chair in Creative Writing. He taught one or two classes each semester of about 12 students each, Mr. Kates said.