Actually something like this actually happened to me when I was playing Fallout New Vegas (spoilers) I was climbing up to death mountain (I think that's how you call it) and when I talked to the friendly mutant I followed him, but I went the wrong way and found a shack at the bottom of the mountain, as I was going back up I heard a noise, when I turned around I shat myself... it was a deathclaw, I think you can tell what happen next.