A major cannabis distribution ring in South Australia has been dismantled, with police seizing more than 300 cannabis plants and $660,000 worth of weapons.

More than 200 police raided about 50 homes across Adelaide yesterday, uncovering 52 kilograms of cannabis and a total of 13 weapons, which included firearms, Tasers and a crossbow.

Items seized: 312 cannabis plants

312 cannabis plants 52kg of cannabis

52kg of cannabis Small amount of amphetamine and steroids

Small amount of amphetamine and steroids $100,550.00 cash

$100,550.00 cash 1 starter pistol

1 starter pistol 5 rifles

5 rifles 3 shotguns

3 shotguns 1 Taser

1 Taser 3 rounds of ammunition

Police also seized $110,000 in cash during the raids.

Another five properties were raided in Western Australia and The Northern Territory.

Twenty people were charged in SA with a further three charged in WA and one in NT.

Detective Chief Inspector Steve Taylor said SA police were working with federal officers and he expected further arrests would be made.

"We can fairly confidently say in this case it's not just a disruption, but is a complete dismantling of this criminal syndicate," he said.

"However I would say that we would expect further arrests to occur in the next day or two.

"It's a fairly good investigation and the results speak for themselves.

"We're very pleased to be able to take these illicit drugs off the street of South Australia and indeed these drugs were destined for interstate, so again we are very pleased to be able to do that."

He warned the public not to get involved in the distribution of illicit drugs.

"The message here is clear, if you deal in illicit drugs there is a strong probability that you will be caught," he said.

"It may take us some time to catch you but we will. Don't risk it."

Detective Chief Inspector Taylor said Operation Deluge began in January this year and had seen a total of 33 people arrested and more than 120kg of cannabis seized.

He estimated the total street value of drugs seized throughout the operation was in excess of $1 million.

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