This week, the U.S. Commission on Civil Rights announced that it will investigate whether colleges discriminate against women by admitting less qualified men. It will strike many as odd to think that American men would need such a leg up. From the men-only basketball games at the White House to the testosterone club on Wall Street, we seem surrounded by male dominance.

And yet, when looking to America's future—trying to spot the future entrepreneurs and inventors—there's reason to be troubled by the...