Well, Republicans were saying before the election that if Obama/Biden won and McCain/Palin lost, things were going to get ugly:

Jim Nuzzo, a White House aide to the first President Bush, dismissed Mrs Palin's critics as "cocktail party conservatives" who "give aid and comfort to the enemy". He told The Sunday Telegraph: "There's going to be a bloodbath. A lot of people are going to be excommunicated. David Brooks and David Frum and Peggy Noonan are dead people in the Republican Party. The litmus test will be: where did you stand on Palin?"

Sure enough:

RedState is pleased to announce it is engaging in a special project: Operation Leper. We're tracking down all the people from the McCain campaign now whispering smears against Governor Palin to Carl Cameron and others. Michelle Malkin has the details. We intend to constantly remind the base about these people, monitor who they are working for, and, when 2012 rolls around, see which candidates hire them. Naturally then, you'll see us go to war against those candidates. It is our expressed intention to make these few people political lepers.

Robert Farley has it about right:

I expect that the effort will make Palin more toxic to anyone who's not in the Republican base, but won't touch her position within the base. Sarah Palin is too big to fail. Bill Kristol has staked his prestige on Palin's future, and the simple fact that she thought Africa was a country isn't going to make he and his back down. He's too deeply invested in her, and everyone else in the conservative punditariat is too deeply invested in him. If she crashes, everyone goes down. I foresee two possible futures; in one, Kristol starts walking everyone back from the brink in a year or two, and Palin's future Presidential candidacy goes down the memory tube. In the other, we get Sarah! 2012, and a Goldwater style annihilation next time around. I'm guessing door #2.

Couldn't happen to a more deserving bunch.