0 of 16

A valuable lesson was learned this week in the NFL—do not ever pick against the Buffalo Bills.

Three straight weeks, I've picked against Buffalo, and three straight weeks they've won in impressive fashion. Guess who won't be picking the Bills to lose this week?

How am I doing through three weeks? Pretty good.

Week 3 Record: 11-5 (my worst week so far)

2011 Season Record: 34-14

Week 4 features a less exciting schedule than we have seen thus far. There are key matchups, though.

Will Detroit be able to remain undefeated when it has to travel to Dallas to take on the Cowboys? Can the 49ers move to 3-1 by winning on the road against a beat-up Eagles team?

My weekly picks plus a breakdown for each game are inside. Enjoy!