The Seahawks suffered a heavy defeat to the Arizona Cardinals on Sunday night, but it wasn’t the scoreline that hurt the most. Sure, a 27-13 loss sucks, but the larger picture is certainly more affected by the potential season-ending injuries to running back duo Chris Carson - who has 1230 yards to stand fifth in rushing - and C.J. Prosise, as well as losing offensive lineman Duane Brown due to meniscus troubles. This is a heavy blow to an offense which relies heavily on its ground-and-pound game to maintain momentum. The ‘Hawks have the third-best rushing attack in the league, and that has now been cruelly robbed from Russell Wilson and Pete Carroll. As well as those offensive injuries, the defense is banged up too; defensive end Jadeveon Clowney - who bossed the 49ers earlier in the season - has missed the last two games with core troubles, whilst key cornerback Shaquill Griffin has also been out with hamstring issues. The defensive back may return for this titanic clash on Sunday after returning to practice on Tuesday, but it truly is a race against time to be fit - a sentiment that is becoming worryingly common in Seattle.

As for the 49ers, this 2019 campaign will be fondly looked back on by fans largely irrespective of Sunday’s result; it has been a season-long coming out party for Kyle Shanahan’s roster. Their defense is ranked second in yards-per-game (YPG) allowed, and their pass-defense is the best in the league - they have allowed just 165.6 YPG. In terms of injuries, the football gods appear to be smiling on the Golden City. Wide receiver Deebo Samuel has been battling a shoulder injury but should still be fit to face the Seahawks, and it appears only Dee Ford will be unavailable for the trip to Seattle.