NIPT/Cell Free DNA Screening Predictive Value Calculator Your browser does not support JavaScript which is required for this application. Please enable JavaScript or contact your system administrator for support in enabling JavaScript for this page. You may alternatively view this application on your mobile device which may support JavaScript.

Terms of Use

The NIPT/Cell Free DNA Screening Performance Calculator (“Calculator”), also known as "NIPT/cfDNA Performance Calculator", is provided solely for use by healthcare professionals with an understanding of positive predictive value (“PPV”) and negative predictive value (“NPV”). The Calculator is intended to aid such healthcare professionals in counseling their patients about PPV and NPV relative to certain non-invasive prenatal tests (“NIPT”) and the clinical meaning of the patient’s screening results. The Calculator should not be used to provide risk assessment independent of clinical correlation/context and is not intended to replace a health care professional’s best medical judgment based on the clinical circumstances.

The Calculator is provided for educational and informational purposes only, and neither the Perinatal Quality Foundation (“Foundation”) nor the National Society of Genetic Counselors (“NSGC”) approves or endorses any specific values, methods, practices, or sources of information. Use of the Calculator does not create any provider-patient relationship with the Foundation, NSGC or their respective committee or board members, or Sound Information Services, LLC.

The Calculator uses statistical calculations based on the information provided by the user to determine the predictive values of NIPT/Cell Free DNA Screening utilizing prevalence information based on mateage and population study. The values generated by the Calculator should not be construed as dictating an exclusive course of management, nor does the use of such predictive values guarantee a particular outcome. Proper use of the Calculator requires that the user (i) input accurate data; and (ii) have sufficient understanding of the methodology used and relevance of the results generated. Neither NSGC nor the Foundation guarantees, or take any responsibility whatsoever for, the accuracy of the results generated by the Calculator.

In consideration of your use of the Calculator, you covenant not to sue, and further waive, release and discharge, NSGC, the Foundation, and any person and/or organization associated with the Calculator from any and all claims to liability for death, personal injury, or property damage of any kind or nature, whatsoever arising out of, or in the course of, your use of the Calculator. Neither the Foundation, NSGC, or any other individual, organization or other party involved in the preparation or publication of the Calculator or this website shall be liable for any special, consequential, or exemplary damages resulting in whole or part from any use of or reliance upon the Calculator, the results or values generated by the Calculator or other information or materials included on this website.

Clicking “Accept” constitutes your agreement with the terms set forth above.