Cleveland makes history again.

Days after overcoming a record-setting 25-point deficit on the road, the Browns became one of the first teams to undergo the NFL’s new HGH testing, which officially kicked off this week.

Browns offensive guard John Greco said players came into the facility Tuesday and were told they needed a test that took about 20 minutes to administer.

According to an NFLPA letter obtained by ESPN's Adam Schefter, five players on eight teams will be randomly selected for testing each week.

“Guys were showing up and they were like, ‘Hey, you’ve got to do your test today,’” Greco said. “It seems like it’s just going to be a week-to-week thing.”

The NFL and NFLPA took years to agree on testing parameters to complement the current PED test.

Despite years of speculation about what took so long, many players still don't know what to expect. New York Giants running back Rashad Jennings told local media this week he didn't know the league was testing.

"To be honest, other than the numbers of people being randomly selected, I don’t know much about it," Greco said.