Tania Thomas, one of the first visitors to see the renovated and expanded Museum of Modern Art, had the new floor map in hand and an audio guide. It wasn’t enough.

“We’re walking in the wrong direction,” Ms. Thomas, of Larchmont, N.Y. , said to her daughter Eliana, 11, as they wandered the fifth floor. “Should we go to the beginning and start over?”

Jeff Madrick, a longtime museum member, said he was surprised by some of the artworks he hadn’t seen before. “I don’t remember the small Légers or the Stuart Davis,” he said, referring to work by the French painter Fernand Léger and by the American modernist painter.