Qatar has accused Saudi Arabia of trying to engineer "regime change" during its four-month blockade of its Gulf neighbour.

Foreign Minister Sheikh Mohammed bin Abdulrahman Al Thani told CNBC on Tuesday that Riyadh is attempting to destabilise Qatar's leadership.

"We see [Saudi] government officials talking about regime change … We see a country that is bringing back the dark ages of tribes and putting them together in order to create a pressure on connected tribes in Qatar," he said.

Saudi Arabia, the United Arab Emirates, Bahrain and Egypt severed diplomatic and trade links with Qatar on June 5, accusing Doha of supporting "extremism and terrorism" and cosying up to Iran - a regional nemesis.

Qatar has vehemently denied all allegations.

Sheikh Mohammed said the plan of the blockading countries was not to thwart "terrorism" but to "disrespect and bully".

"It is nothing to do with stopping financing terrorism or hate speech while they are doing the same by promoting incitement against my country, promoting a regime change in my country," he told the US broadcaster.

Qatar is the world's largest exporter of liquefied natural gas, and also houses the region's biggest US military base with more than 11,000 American troops.

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Sheikh Mohammed said the blockade has impeded the fight against the Islamic State of Iraq and the Levant (ISIL) group in the region.

The airspace blockade meant that Qatari aircraft providing logistical support for the American military base have been diverted, and Qatari officers participating in operations against ISIL were expelled from the Bahrain-based US military headquarters.

"So there are a lot of things which undermine ... the global efforts in countering ... Daesh," Sheikh Mohammed said, referring to ISIL by an Arabic acronym.