NASHVILLE -- The Titans open the 2019 season on the road against the resurgent Cleveland Browns.

The team's home opener comes in Week 2 against their AFC South rivals, the Indianapolis Colts, before a Week 3 contest at the Jacksonville Jaguars in primetime on Thursday, September 19.

Those are among the highlights on the schedule, which includes seven games against teams that went to the playoffs in 2018.

The Titans play three of their first four games on the road, and two of their final three games against the Houston Texans, including the season finale in Houston.

The Kansas City Chiefs and MVP quarterback Patrick Mahomes visit the Titans on November 10, and the Drew Brees-led New Orleans Saints visit Nissan Stadium on December 22.

Currently, 11 of the team's 16 games are slated to begin at noon, although games in Weeks 11-17 are subject to being flexed to night games. The team's by weekend is November 17.

The Titans' schedule is the ninth most difficult in the NFL based upon their opponents' combined 2018 winning percentage of .515 (131-124-1). The Titans finished 9-7 in 2018.

"I try not to get too wrapped up in what the schedule looks like from year to year," Titans coach Mike Vrabel said. "All schedules present challenges and this one certainly does as well. It is always exciting to see what lies ahead and start preparing for those opponents.

"I have learned through the years as a player and coach that how a schedule looks in April ends up looking very different once you have played it."