Four key GOP senators will become the targets of a new series of TV ads opposing the ObamaCare repeal bill in the Senate.

The ads, launched by Save My Care, will target Sens. Lisa Murkowski Lisa Ann MurkowskiMomentum growing among Republicans for Supreme Court vote before Election Day Collins: President elected Nov. 3 should fill Supreme Court vacancy Barrett seen as a front-runner for Trump Supreme Court pick MORE (Alaska), Susan Collins Susan Margaret CollinsJeff Flake: Republicans 'should hold the same position' on SCOTUS vacancy as 2016 Trump supporters chant 'Fill that seat' at North Carolina rally Momentum growing among Republicans for Supreme Court vote before Election Day MORE (Maine), Dean Heller Dean Arthur HellerOn The Trail: Democrats plan to hammer Trump on Social Security, Medicare Lobbying World Democrats spend big to put Senate in play MORE (Nev.) and Shelley Moore Capito Shelley Wellons Moore CapitoSecond GOP senator to quarantine after exposure to coronavirus GOP senator to quarantine after coronavirus exposure Hillicon Valley: Zuckerberg acknowledges failure to take down Kenosha military group despite warnings | Election officials push back against concerns over mail-in voting, drop boxes MORE (W.Va.), who are all seen as deciding votes on the Senate GOP's Better Care Reconciliation Act.

The ads warn the senators against accepting any "backroom deals."

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Senate Majority Leader Mitch McConnell Addison (Mitch) Mitchell McConnellMomentum growing among Republicans for Supreme Court vote before Election Day Trump expects to nominate woman to replace Ginsburg next week Video of Lindsey Graham arguing against nominating a Supreme Court justice in an election year goes viral MORE (R-Ky.) is working with moderates to try to get their support for the bill, which could involve more money for the opioid crisis or changes to the bill's Medicaid language.

All four senators are currently against the bill.

The ads are different for each senator and highlight comments they've made in the past about the bill.

"When the Senate unveiled its devastating healthcare repeal plan, Senator Heller said: 'I'm telling you right now, I cannot support a piece of legislation that takes insurance away from tens of millions of Americans and hundreds of thousands of Nevadans.' "

"But now, Washington politicians are pressuring Heller to support their secret backroom deals that will gut Medicaid and take away coverage from over 120,000 Nevadans," says the narrator.

Congress returns from a one-week recess Monday, and McConnell will continue working on getting the votes for the bill.

It needs a least 51 votes to pass, but moderates have worried the bill would cause too many people to lose coverage and conservatives say the bill leaves too many of ObamaCare's regulations in place.