Criminal Minds is about to make history.

ET exclusively debuts the first footage from the upcoming 14th season, which will open with the show's milestone 300th episode and pick up moments after the dramatic season 13 cliffhanger that left Reid (Matthew Gray Gubler) and Garcia (Kirsten Vangsness) in huge trouble.

“We’re so excited to announce that season 14 will kick off with our historical 300th episode! It’s an action-packed hour of our team in never-before-seen jeopardy," executive producer and showrunner Erica Messer tells ET. "This episode is a love letter to our fans as a way of saying thank you for being with us all these years and here’s to many more.”

In the new 30-second teaser, which you can watch above, the rest of the BAU scramble to save their friends and some members of the team -- most notably J.J. (A.J. Cook) -- have a harder time than the others.

"We stand beside one another through good, through bad... because we're family," Rossi (Joe Mantegna) says, while Garcia -- held hostage by a mass murderer -- desperately questions, "What do they want?!"

If the promo is any indication, it's looking bad for Reid and Garcia.

Following the heart-stopping season 13 cliffhanger in April, Messer spoke with ET about what viewers can expect when the show returns this fall, hinting that all the core characters will be major players for the 300th hour.

"There are many different ways to go, but, obviously, we want our wonderful heroes to be in the 300th episode," Messer said at the time. "It would probably be a matter of our team trying to solve one of the biggest cases they've ever seen without two of the most important players on their team."

Criminal Minds premieres Wednesday, Oct. 3 at 10 p.m. ET/PT on CBS.

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