Carolina selected the former Ole Miss offensive tackle in the second round with the 37th overall pick. In 2018, Little was named to the All-SEC first team and earned All-America second team honors. He started every game at left tackle for the Rebels each of his last two seasons. Little, 6-5 and 310 pounds, allowed just 26 total pressures and three sacks in 993 pass-blocking snaps over those two seasons, according to Pro Football Focus.