Police say they are concerned by a recent spike in drug-related deaths following the death of a 25-year-old Innaloo man on New Year's Day.

The man's death is believed to be related to a lethal hallucinogenic drug, paramethoxymethamphetamine or PMMA, that may have been sold as ecstasy, and may go by the street name "death".

The drug PMMA, which goes by the street name 'death' and is often sold as ecstasy, can be fatal.

This case is the first known death in WA to be related to PMMA, similar to a death in 1999 related to paramethoxyamphetamine, or PMA, a slightly different but equally dangerous drug.

Detective Senior Sergeant Neville Beard from the coronial investigations unit said he believed the deceased man took a cocktail of drugs and alcohol in the days leading up to his death.