Grapefruit (Citrus paradisi) is nutritious fruit full of vitamin C, antioxidants, and a tangy-sweet flavor. However, research points to hundreds of drug interactions -- many of which may be serious -- with grapefruit.

Medications can interact with all forms of grapefruit - the fresh fruit, juice or even the frozen concentrate can result in problems. Interactions may occur with commonly used drugs - such as those that lower cholesterol, treat high blood pressure, or even those that fight cancer.

Tip: If you drink grapefruit juice, always have your pharmacist check for drug interactions with any new prescription or over-the-counter (OTC) drug.