In spite of its reputation, Florida is no longer the dominion of retirees and spring breakers — in fact, trendy enclaves are blossoming across the state, from the Atlantic to the Gulf Coast, and becoming destinations in their own right.

Chief among them is Fort Lauderdale, which for years has lurked in the shadow of Miami, just 30 miles to the south. But recently “the Venice of America” has carved out its own sophisticated beach scene, with swanky new eateries and luxury hotels that can compete with some of the best Miami has to offer.

Nearing completion is the massive $55 million renovation of the W Fort Lauderdale (from $295), which will bring a beachier vibe to the common areas and all 430 rooms and suites. What won’t change: the hotel’s perennially packed Steak 954, Stephen Starr’s oceanfront ode to beef.

Another seaside draw is Burlock Coast Seafare & Spirits, tucked inside the recently renovated Ritz-Carlton Fort Lauderdale (from $510). The combination restaurant-cafe-bar just kicked off its first monthly farmers market, where you can pick up items offered in the restaurant, including artisanal breads from Wynwood, Miami-based Zak the Baker. And plan ahead to score a seat at Nisi, a new high-end Mediterranean eatery helmed by two Estiatorio Milos alums who bring a refined, modern touch to classic Greek cooking.

For a more serene spot on Florida’s eastern shore — one with long stretches of golden sand and few tourists — Vero Beach fits the bill. This tiny Treasure Coast town isn’t where you’d expect to find a celeb-helmed hotel, but singer Gloria Estefan and her husband, Emilio, made it the setting for their 94-room Costa d’Este Beach Resort & Spa (from $253).

Dine at the hotel’s oceanfront Wave Kitchen & Bar, whose Cuban-influenced menu sources locally grown, organic products. Then head next door for live music at the landmark Waldo’s.

Sugary-white sand and warm, tranquil blue waters — for that, look to Florida’s Gulf Coast. Consistently voted one of the top 10 beaches in the US, Clearwater Beach has upped its game with the opening of Opal Sands Resort earlier this year (from $326). The grand glassy tower occupies a prime stretch of beach, and you can enjoy unbeatable water views from every one of its 230 rooms.

Nearby St. Petersburg is a fun, gay-friendly city bursting with an eclectic assortment of restaurants and bars. It’s also home to the Dalí Museum, which will host what promises to be one of the top art shows this winter: “Frida Kahlo at the Dalí” ($24). More than 60 works from the iconic artist will be on view from Dec. 17 to April 17, 2017, and the exhibit will extend to the museum’s grounds, showcasing plants and flowers found in her garden at Casa Azul in Mexico City.

To the south, the tony oceanfront enclave of Sarasota is becoming an even more posh destination. That’s thanks in part to the 266-room Ritz-Carlton Sarasota, which completed a property-wide renovation last year (from $342).

Here, guests can take advantage of the hotel’s exclusive beach club, with a shuttle that spirits them 3 miles offshore to private Lido Key.

And Sarasota’s Ringling Museum of Art not only recently gained a fine-dining restaurant, Muse, this spring it also unveiled its Center for Asian Art ($25).

And Florida isn’t just about its coastline: Just outside Orlando, in the ritzy suburb of Winter Park — where Paul McCartney and Nancy Shevell keep a home — you’ll find the two-time winner of Condé Nast Traveler’s Readers’ Choice Award for best hotel in Florida, The Alfond Inn (from $237).

The 112-room boutique stay is filled with a rotating selection of contemporary art, courtesy of the local Rollins College. It’s just a few blocks to the heart of the village, Park Avenue, lined with upscale boutiques and chichi restaurants like Luma on Park and the Brooklyn-esque Italian favorite, Prato.