As audience members threw red and white roses onto the Foxwoods Theater stage, two of the musical’s former stars, Reeve Carney (who played Peter Parker for two and a half years) and Patrick Page (who won strong reviews as the Green Goblin), also ran onto the stage with bouquets for current cast members. A couple of actors held banners that read, “Always Bet on Red (and Blue)!” and “Vegas, Baby!,” the latter a reference to the producers’ announcement that they intend to open a revamped version of “Spider-Man” in Las Vegas in 2015.

No mention was made of the show’s famous composers, Bono and the Edge of U2, nor its original director, Julie Taymor, who was fired during preview performances after clashing with the two musicians and the producers over strategies to improve “Spider-Man.” Bono, the Edge, and Ms. Taymor did not attend Saturday’s performance; only the fourth creator of the show, Glen Berger, who co-wrote the script with Ms. Taymor, was in the audience. (Mr. Berger has been busy lately selling copies of a tell-all memoir about the making of the musical and the ensuing infighting.)

The vibe inside the theater was festive, with Mr. Carney, Mr. Page and other audience members going to lengths to loudly applaud the first entrances of several actors. The performance included only one inside joke about the closing of the show: A character reads aloud a newspaper headline, “Super-hero mega-musical defies doubters, runs three years on Broadway.” A cast party was also planned for later that night at John’s Pizzeria in Times Square.

“Spider-Man” had 1,248 performances in all, a healthy run by Broadway standards – but not nearly enough to come close to earning back the original $75 million capitalization to create and stage the musical. Most Broadway musicals are capitalized at between $10 million to $15 million; the costs for “Spider-Man” were much higher because of years-long delays in making the show as well as hefty set and costume budgets, salaries for scores of people on the creative team, and a costly retooling of the show during previews, among many other budget items.

The producers and investors on “Spider-Man” are expected to lose up to $60 million on the Broadway run, though they could still see some financial return if the show runs in Las Vegas and proves popular. The producers are negotiating with the Las Vegas casino owner Steve Wynn about putting the musical into one of his properties and adding even more special effects. Final terms have yet to be reached.