1. Luterbacher, J. S. et al. Solvent-enabled nonenyzmatic sugar production from biomass for chemical and biological upgrading. ChemSusChem 8, 1317–1322 (2015).

2. Luterbacher, J. S., Alonso, D. M. & Dumesic, J. A. Targeted chemical upgrading of lignocellulosic biomass to platform molecules. Green. Chem. 16, 4816–4838 (2014).

3. Questell-Santiago, Y. M. & Luterbacher, J. S. in High Pressure Technologies in Biomass Conversion (ed. Lukasik, R. M.) 9–36 (Royal Society of Chemistry, Croydon, 2017).

4. Shuai, L. et al. Formaldehyde stabilization facilitates lignin monomer production during biomass depolymerization. Science 354, 329–333 (2016).

5. Wyman, C. E., Cai, C. M. & Kumar, R. in Encyclopedia of Sustainability Science and Technology (ed. Meyers, R. A.) 1–27 (Springer, New York, 2017).

6. Kumar, A. K. & Sharma, S. Recent updates on different methods of pretreatment of lignocellulosic feedstocks: a review. Bioresour. Bioprocess. 4, 7 (2017).

7. Alonso, D. M. et al. Increasing the revenue from lignocellulosic biomass: maximizing feedstock utilization. Sci. Adv. 3, e1603301 (2017).

8. Lan, W., Amiri, M. T., Hunston, C. M. & Luterbacher, J. S. Protection group effects during α,γ-diol lignin stabilization promote high-selectivity monomer production. Angew. Chem. Int. Ed. 57, 1356–1360 (2018).

9. Nyoo Putro, J., Edi Soetaredjo, F., Lin, S.-Y., Ju, Y.-H. & Ismadji, S. Pretreatment and conversion of lignocellulose biomass into valuable chemicals. RSC Adv. 6, 46834–46852 (2016).

10. Luterbacher, J. S. et al. Nonenzymatic sugar production from biomass using biomass-derived γ-valerolactone. Science 343, 277–280 (2014).

11. Haghighi Mood, S. et al. Lignocellulosic biomass to bioethanol, a comprehensive review with a focus on pretreatment. Renew. Sustain. Energy Rev. 27, 77–93 (2013).

12. Neuman, R. P. & Walker, L. P. Solute exclusion from cellulose in packed columns: experimental investigation and pore volume measurements. Biotechnol. Bioeng. 40, 218–225 (1992).

13. Peterson, A. A. et al. Thermochemical biofuel production in hydrothermal media: a review of sub- and supercritical water technologies. Energy Environ. Sci. 1, 32–65 (2008).

14. Bergius, F. Conversion of wood to carbohydrates. Ind. Eng. Chem. 29, 247–253 (1937).

15. Binder, J. B. & Raines, R. T. Fermentable sugars by chemical hydrolysis of biomass. Proc. Natl Acad. Sci. USA 107, 4516–4521 (2010).

16. Tao, L. et al. NREL 2012 Achievement of Ethanol Cost Targets: Biochemical Ethanol Fermentation via Dilute-Acid Pretreatment and Enzymatic Hydrolysis of Corn Stover (NREL, 2014); https://doi.org/10.2172/1129271

17. Klein-Marcuschamer, D., Oleskowicz-Popiel, P., Simmons, B. A. & Blanch, H. W. The challenge of enzyme cost in the production of lignocellulosic biofuels. Biotechnol. Bioeng. 109, 1083–1087 (2012).

18. Gschwend, F. J. V., Brandt-Talbot, A., Chambon, C. L. & Hallett, J. P. in Ionic Liquids: Current State and Future Directions Vol. 1250 (eds Shiflett, M. B. & Scurto, A. M.) 209–223 (American Chemical Society, Washington DC, 2017).

19. Moriarty, K. L., Milbrandt, A. R., Warner, E., Lewis, J. E. & Schwab, A. A. 2016 Bioenergy Industry Status Report (NREL, Golden, 2018).

20. Liu, G., Zhang, J. & Bao, J. Cost evaluation of cellulase enzyme for industrial-scale cellulosic ethanol production based on rigorous Aspen Plus modeling. Bioprocess. Biosyst. Eng. 39, 133–140 (2016).

21. Mellmer, M. A. et al. Solvent effects in acid-catalyzed biomass conversion reactions. Angew. Chem. Int. Ed. 53, 11872–11875 (2014).

22. Mellmer, M. A., Alonso, D. M., Luterbacher, J. S., Gallo, J. M. R. & Dumesic, J. A. Effects of γ-valerolactone in hydrolysis of lignocellulosic biomass to monosaccharides. Green Chem. 16, 4659–4662 (2014).

23. Ghosh, A., Bai, X. & Brown, R. C. Solubilized carbohydrate production by acid-catalyzed depolymerization of cellulose in polar aprotic solvents. Chem. Select 3, 4777–4785 (2018).

24. Lee, Y. Y., Iyer, P. & Torget, R. W. in Recent Progress in Bioconversion of Lignocellulosics (ed. Tsao, G. T.) 93–115 (Springer, Berlin, 1999).

25. Yang, B., Tao, L. & Wyman, C. E. Strengths, challenges, and opportunities for hydrothermal pretreatment in lignocellulosic biorefineries. Biofuels Bioprod. Bioref. 12, 125–138 (2018).

26. Han, J., Luterbacher, J. S., Alonso, D. M., Dumesic, J. A. & Maravelias, C. T. A lignocellulosic ethanol strategy via nonenzymatic sugar production: process synthesis and analysis. Bioresour. Technol. 182, 258–266 (2015).

27. Eerhart, A. J. J. E. et al. Fuels and plastics from lignocellulosic biomass via the furan pathway; a technical analysis. RSC Adv. 4, 3536–3549 (2013).

28. Eerhart, A. J. J. E., Patel, M. K. & Faaij, A. P. C. Fuels and plastics from lignocellulosic biomass via the furan pathway: an economic analysis. Biofuels Bioprod. Bioref. 9, 307–325 (2015).

29. Qian, M., Liauw, M. A. & Emig, G. Formaldehyde synthesis from methanol over silver catalysts. Appl. Catal. Gen. 238, 211–222 (2003).

30. Bahmanpour, A. M., Hoadley, A. & Tanksale, A. Formaldehyde production via hydrogenation of carbon monoxide in the aqueous phase. Green Chem. 17, 3500–3507 (2015).

31. Shuai, L. & Luterbacher, J. Organic solvent effects in biomass conversion reactions. ChemSusChem 9, 133–155 (2016).

32. Mössinger, D., Scheytt, H., Uihlein, K., Wunderlich, D. & Zimmerer, B. High-tenacity viscose multifilament yarn with low yarn linear density. US Patent US20150322595A1 (2015).

33. Ronald, R., Martin, R. T. & Richardson, W. C. Filaments of regenerated cellulose. US Patent US3388117A (1968).

34. Pagán-Torres, Y. J., Wang, T., Gallo, J. M. R., Shanks, B. H. & Dumesic, J. A. Production of 5-hydroxymethylfurfural from glucose using a combination of Lewis and Brønsted acid catalysts in water in a biphasic reactor with an alkylphenol solvent. ACS Catal. 2, 930–934 (2012).

35. Choudhary, V., Sandler, S. I. & Vlachos, D. G. Conversion of xylose to furfural using lewis and brønsted acid catalysts in aqueous media. ACS Catal. 2, 2022–2028 (2012).

36. Román-Leshkov, Y., Moliner, M., Labinger, J. A. & Davis, M. E. Mechanism of glucose isomerization using a solid Lewis acid catalyst in water. Angew. Chem. Int. Ed. 49, 8954–8957 (2010).

37. Choudhary, V., Pinar, A. B., Sandler, S. I., Vlachos, D. G. & Lobo, R. F. Xylose isomerization to xylulose and its dehydration to furfural in aqueous media. ACS Catal. 1, 1724–1728 (2011).

38. Robyt, J. F. Essentials of Carbohydrate Chemistry (Springer, New York, 1998).

39. Nimlos, M. R., Qian, X., Davis, M., Himmel, M. E. & Johnson, D. K. Energetics of xylose decomposition as determined using quantum mechanics modeling. J. Phys. Chem. A 110, 11824–11838 (2006).