The Rev. Jesse Jackson blasted President Trump’s Cabinet appointees on Sunday, saying picks such as Attorney General Jeff Sessions Jefferson (Jeff) Beauregard SessionsTrump's policies on refugees are as simple as ABCs Ocasio-Cortez, Velázquez call for convention to decide Puerto Rico status White House officials voted by show of hands on 2018 family separations: report MORE and Education Secretary Betsy DeVos make it "very difficult” to work with the new administration.

“It’s going to be very difficult, because Trump’s appointees are hostile to our interests,” Jackson told radio host John Catsimatidis on AM 970 in New York.

The civil rights activist painted Sessions as an opponent of social and racial justice, arguing he has stood at odds with the Voting Rights Act and desegregation rulings and calling his appointment “a stab in the heart of our struggle.”

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Jackson also slammed DeVos, accusing her of having “bought her position in government.” Jackson argued the GOP mega-donor was unqualified to hold her position because of her lack of experience in a public school environment.

“Ms. DeVos has never ever been in the public schools,” he said. “Doesn’t have a teaching certificate, never been a principal, never been a superintendent. She just bought her position in government. Hard to discuss education with somebody with those kind of credentials.”

“It seems to me that meeting with Trump is going to be a very difficult thing to do,” he added.

DeVos was narrowly confirmed in the Senate last week, after Vice President Pence cast a tie-breaking vote.

Jackson’s comments on Sunday weren’t the first time the civil rights leader slammed Trump’s appointees.

Jackson last week criticized Trump's appointment of six Wall Street executives to his economic team in an op-ed in the Chicago Sun-Times, voicing concern that the appointees would gut the Consumer Financial Protection Bureau.