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Doctors now have convincing evidence that they put HIV into remission, hopefully for good, in a Mississippi baby born with the AIDS virus — a medical first that is prompting a new look at how hard and fast such cases should be treated.

The case was reported earlier this year but some doctors were skeptical that the baby was really infected rather than testing positive because of exposure to virus in the mom’s blood.

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The new report, published online Wednesday by the New England Journal of Medicine, makes clear that the girl, now 3, was infected in the womb. She was treated unusually aggressively and shows no active infection despite stopping AIDS medicines 18 months ago.

Doctors won’t call it a cure because they don’t know what proof or how much time is needed to declare someone free of HIV infection, long feared to be permanent.

“We want to be very cautious here. We’re calling it remission because we’d like to observe the child for a longer time and be absolutely sure there’s no rebound,” said Dr. Katherine Luzuriaga, a University of Massachusetts AIDS expert involved in the baby’s care.