Thor: Love and Thunder's Natalie Portman is a major supporter of the sequel tackling her character Jane Foster's cancer storyline from the comics.

Love and Thunder is set to feature Foster becoming the wielder of the Asgardian hammer Mjolnir, which some fans have speculated is an adaptation of a comics storyline that also sees the character battling cancer.

Portman chatted to Variety about that possibility in a recent interview. While she couldn't confirm or deny anything, the Oscar winner admitted she'd heard rumblings that Marvel wanted to broach an important topic like cancer.

Alberto E. Rodriguez Getty Images

“It's just very rare that these kinds of big entertainment films look at more serious, real-life issues," she said. "I really don't know anything about it.

"I haven't seen anything, but I've heard the same rumours as you have, and it's exciting to think about.”

In the aforementioned eight-issue comic series, Jane Foster faces the complexities of being able to transform into Lady Thor – while knowing her health will deteriorate each time she does it.

Marvel Comics

Portman's director Taika Waititi called the cancer storyline "a really powerful" part of Thor continuity, leaving the door open to adapting it in Love and Thunder.

"I think it's really cool that she's fighting this thing and there's two battles going on," he also told Variety.

"Personally I really love that storyline. But whether it ends up in the film is yet to be seen."

Thor: Love and Thunder has a release date of November 5, 2021.

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