MONTERREY, Mexico — The Dodgers have the most no-hitters in the majors — and now the most in Mexico, too.

Rookie Walker Buehler and a trio of Los Angeles relievers combined for the franchise’s 23rd no-hitter in a 4-0 victory over the San Diego Padres in the opener of a neutral-site series Friday night.

Mexico had waited since 1999 to host a regular-season big league game, and it got a historic one: the first no-hitter ever outside the U.S. or Canada and the 12th combined no-hitter in major league history.

“It was awesome,” Buehler said. “It’s one of those things, to pitch in a place like this, an atmosphere like this. It was awesome.”

A crowd of 21,536 at Estadio de Beisbol Monterrey saw Buehler stay steady despite early rain. In just his third start in the majors, he went six innings before Tony Cingrani , Yimi Garcia and Adam Liberatore closed it out.

Buehler, a 23-year-old taken in the first round of the 2015 amateur draft, struck out eight and walked three. After 93 pitches, the highly touted right-hander was pulled. Cingrani walked two in the seventh, but the lefty kept the bid intact.

“It’s probably one of the toughest conversations I ever had, I wanted to keep going,” Buehler said. “But they made the choice and the guys finished out and it was cool.”

Buehler overcame wet conditions — the hardest rain fell in the second inning.

“I threw one in high school, but I gave up two runs in the first inning, so that one doesn’t really count,” Buehler said.

Garcia struck out two in a perfect eighth and Liberatore threw a 1-2-3 ninth, striking out Franchy Cordero to end it with the Dodgers’ 146th pitch.

That ended a festive night that began with a ceremonial first pitch thrown by Dodgers great Fernando Valenzuela , who became a star in the U.S. and Mexico and set off “Fernandomania” when he became a fan favorite in the 1980s.

Valenzuela pitched a no-hitter against St. Louis at Dodger Stadium on June 29, 1990, the same night Oakland’s Dave Stewart pitched a no-hitter at Toronto — one of five in Canada, according to the Elias Sports Bureau.

The Dodgers threw this no-hitter on the same night Albert Pujols of the Los Angeles Angels got his 3,000th hit in a game at Seattle. When Pujols hit his 600th home run at home against Minnesota last June 3, Miami’s Edinson Volquez pitched a no-hitter at home against Arizona.

These dual accomplishments evoked memories of the day in 1985, too, when Rod Carew got his 3,000th hit and Tom Seaver won his 300th game.

And the team with the most no-hitters in major league history — Boston is second with 18 — accomplished the feat against the only franchise that hasn’t pitched any.

This series was part of Major League Baseball’s push to internationalize the sport. No doubt, souvenirs from this game will wind up in the Hall of Fame

Buehler’s highest pitch count in the majors is 94 pitches, reached in his previous outing against San Francisco.

“It’s one of those where you’re pretty angry to come out, but the bullpen, the guys that we have, I trust it in their hands, too,” he said. “And it worked out.”

Dodgers manager Dave Roberts isn’t afraid to pull a young pitcher during a no-hitter. He removed then-rookie Ross Stripling from a bid against San Francisco with one out in the eighth inning in 2016. Reliever Chris Hatcher allowed a home run to the next batter.

This one worked out better for Roberts, giving baseball its second no-hitter of the season. Oakland left-hander Sean Manaea threw the first against Boston on April 21.

Joey Lucchesi (3-2) allowed three runs and five hits as the last-place Padres dropped to 11-22.

Matt Kemp had an RBI single on a popup that fell between shortstop Freddy Galvis and right fielder Matt Szczur in short right field in the first inning, and Chris Taylor and Enrique Hernandez hit consecutive homers in the second. Alex Verdugo singled in a run in the sixth against Adam Cimber.

“This is the fourth time that I get to see a no-hitter, but the first one that I’m on the good end of it,” Hernandez said. “Walker was electric and the relievers did a great job. It*s not an easy feat. It*s a night that no one is going to forget.”