Police have charged a man with murder after an axe attack in Sydney's south-west overnight.

About 8.45pm on Thursday, emergency services were called to Sydney Luker Road, Cabramatta West, after reports of a car crash and two men fighting.

It’s alleged the driver deliberately hit another man with his car before getting out and repeatedly striking him with an axe.

A 59-year-old man was found with an axe wound to the head, and died at the scene.