An out-of-control semi caused a multi-car pileup near Box Canyon on the Coquihalla Highway, Friday afternoon.

"A commercial transport vehicle traveling southbound on Highway 5 apparently was unable to stop and collided with 13 other vehicles," said Const. Melissa Wutke.

Highway 5 was closed southbound from around 2:30 p.m. PT until later Friday night.

RCMP said one person was taken to hospital in serious but stable condition, by air ambulance. Several people were taken to local hospitals with minor injuries.

"Fortunately, there have not been any fatalities," said Const. Melissa Wutke.

"We'd like to thank the motoring public for their patience and understanding as getting the injured to hospital was our first priority."

Wutke said the file was under investigation.