A Queensland family who lost relatives on doomed Malaysia Airlines flight MH370 are in mourning again after losing more family members on MH17 in Ukraine.

Irene and George Burrows from Biloela, south of Rockhampton, are still mourning their son Rodney and his wife Mary who were on flight MH370, which disappeared without trace over the southern Indian Ocean in March.

But tragedy has gripped their family a second time.

It has been revealed Irene and George's daughter Kaylene Mann lost her step-daughter Marie Rizk and her husband Albert in the MH17 disaster.

The jet was shot down by a surface-to-air missile over Ukraine, killing all 298 passengers and crew.

In March, Ms Mann faced the media in Brisbane alongside Jayden Burrows - son of Rodney and Mary - to speak of how the family was trying to come to terms with their loss.

Marie and Albert, a real estate agent from Sunbury near Melbourne, were returning home from a month-long holiday with friends in Europe.

Albert (L) and Maree Rizk (3rd from L), who were aboard MH17, with their children Vanessa and James. ( Supplied: Raine and Horne )

The couple have two children and have been described by friend Ken Grech as "beautiful" people.

He said the Rizks had called their son James the night before the flight to notify them of a change to their travel plans.

"[They tried to] move it forward because the interconnecting flight was a nine-hour stay so they thought if they could change their flight they would do so, but unfortunately that didn't occur," Mr Grech said.

"It hasn't really sunk in yet that their parents aren't going to walk in the front door at home."