KITCHENER -- A three-vehicle collision on Hwy. 401 east of Cambridge has left two people dead and sent two people to hospital with non-life threatening injuries.

OPP were called to the crash near Highway 6 north around 3 a.m. on Saturday.

Police say the drivers of a GMC Sierra and a Lexus SUV suffered injuries while two passengers in a Dodge Nitro were pronounced deceased by the coroner.

The two deceased passengers have been identified as 65-year-old Ramnauth Seebachan and 59-year-old Pardmini Seebachan, both from Cambridge. OPP confirm they were husband and wife.

The third driver involved was not injured.

The westbound lanes of Hwy. 401 were closed for the remainder of the morning.

Const. Kevin Westhead of Burlington OPP says the investigation is ongoing and the cause of the collision is not known yet.

"It's a really busy time of travel around the holidays," he said. "There's a lot of traffic on the highways. The OPP's encouraging everybody to travel safely, take their time, not be in a rush, and just get where they're going safely to avoid this type of situation."

Police say they haven't ruled out any possibilities in the investigation and can't confirm if charges will be laid.

CLEARED:ROAD CLOSURE: #Hwy401 WB lanes atHwy 6 S #Puslinch - All lanes are now OPEN. ^ag pic.twitter.com/IqFXj8Lkw0 — OPP GTA Traffic (@OPP_GTATraffic) December 21, 2019