Two men linked to the Comanchero bikie gang in Western Australia may have been set up when they were shot and hospitalised in Melbourne's northwest but they're nevertheless refusing to talk to Victorian cops.

The men, aged 28 and 30, were injured on Tuesday night when at least 12 shots were fired in a residential street in Attwood.

Those behind the shooting remain on the run.

Detective Acting Senior Sergeant Daniel Ryan from Victoria Police's anti-bikie task force says the interstate victims are known to police and aren't cooperating with investigators.

"We believe the victims were associated to the Comanchero outlaw motorcycle gang in Western Australia," he told reporters on Wednesday.

"The victims are not cooperating which makes it somewhat problematic."

Police believe the men were in Attwood for a meeting at a paddock near Lavery Place.

Detectives don't know what that meeting was about.

The two injured men had arrived in a white Mercedes-Benz with two others - also from WA - about 8pm on Tuesday.

They left the vehicle and were approached by two attackers who fired a number of shots at them, police say.

Investigators believe the assailants were last seen running towards Kenny Street.

Paramedics treated the 28-year-old for gunshot wounds at the scene and were called 45 minutes later to treat the 30-year-old at a nearby bottle shop.

The shooting victims remain in hospital in a stable condition.

Police say they will look into whether the attack was part of a set up.

"It wasn't a random shooting it was targeted," Det Act Sen Sgt Ryan said.

During a line search of the area on Wednesday police found two shell casings and a stolen white Volkswagen Golf seen at the time of the shooting.