The Brisbane Supreme Court has reopened almost three hours after a bomb threat forced the evacuation of 600 people from the building.

A threatening call was made to the court registry about 8.50am and prompted the bomb squad and sniffer dogs to be called in to sweep the building for any devices or suspicious items.

Police are seen standing guard outside the Queen Elizabeth II Courts of Law building after the building was evacuated because of a bomb threat. Credit:AAP

Despite a police spokeswoman initially connecting the threat and a "high-profile case" being dealt with in court on Monday, Inspector Steve Flori later said there was no evidence to link the threat with any court matter or the fact that jurors had arrived for the start of their week-long jury duty.

"We have done a risk-based search of the building and cleared the building of any devices or suspicious activity," he said.