A wrong-way crash on Interstate 65 early this morning killed a Shelby County woman and Calera man.

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Kizzy D. Haynes, 39, of Maylene, reportedly was driving the wrong way on I-65 South near Calera when her 2005 Mercedes E320 collided with a Kia driven by Larry Albert Hampton, 51, of Calera, state troopers said.

Haynes and Hampton were pronounced dead at the scene of the 4:41 a.m. crash, senior state trooper Chuck Daniel said in statement.

"The preliminary investigation indicates that Haynes was driving the wrong way on Interstate 65 at the time of the crash," Daniel said.

The crash, which occurred at mile marker 229 near Calera, tied up traffic but troopers reported that the wreck had been cleared and traffic was flowing again by 7:30 a.m.

Further details were not available as the crash remains under investigation.