Current military deployments have resulted in many psychological and physical health issues and created interest in protective measures to mitigate effects of prolonged and repetitive stress. Mindfulness training has been successfully used for stress reduction in other contexts. The following case report presents a detachment of U.S. Marines who received Mindfulness-Based Mind Fitness Training (MMFT) prior to deployment. Self-report measures of mindfulness, perceptions of stress, predictors of compliance with mindfulness practice, and time spent engaging in practice were indexed. More time spent engaging in practice corresponded with greater self-reported mindfulness; increases in mindfulness were associated with decreases in perceived stress.