Talk show host Bill Maher said Tuesday night on “Piers Morgan Live” that he was certain the Affordable Care Act would succeed, despite technical issues and political opposition to the program.

“Every program of this size was a headache at first,” Maher said. “So was (George W.) Bush’s Medicare prescription drug program for the old folks. Remember, ‘Hey, free Viagra, have a boner on George Bush — remember me at the polls.’ Social security, Medicare — all these programs have these kind problems when you start with them.”

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The host of HBO’s “Real Time With Bill Maher” said President Barack Obama’s signature health care reform law was more popular than Republicans make it out to be.

“Even with all the problems, in four polls last week, Obamacare is more popular than ever,” Maher said. “Republicans like to cite this statistic that something like 54 percent of the people are against Obamacare. It’s very, very misleading. That includes the 16 percent of people who think it doesn’t go far enough.”

Maher said women are driving the program’s popularity and would be the eventual reason it succeeds.

“Yes, young men do not want to sign up because they think they’re invincible,” Maher said. “Women get it because women are a little more complicated. You know, they want contraception, they want breast exams (and) they’re a little smarter about that, too. They don’t think they’re invincible.”

He said the program would become even more popular because Americans want health care coverage.

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“It’s a life and death issue, and again, it was there, it was created because people were dying and the country was going broke,” Maher said. “It was going to be a rocky birth, but it’s not going to fail.”

Watch this video clip of the interview posted online by CNN: