Nashville has its first case of coronavirus.

Nashville Mayor John Cooper confirmed an adult female is the city’s first presumptive case of COVID-19, the illness caused by coronavirus. The case is not considered travel related and the woman is self-isolated at home, WKRN reported.

The woman does not have children in Metro Nashville Public Schools, the station reported.

Another man in Williamson County, Tennessee is also quarantined after testing positive for the virus. The man traveled on a nonstop, round-trip flight between Boston and the Nashville International Airport.

Here are the latest coronavirus updates:

Coronavirus death toll rises to 22

The U.S. death roll from coronavirus rose to 22 over the weekend with two more COVID-19-related deaths in Washington state. Nineteen of the deaths were in Washington state, 17 of them associated with LifeCare Center.

Two people have died in Florida and one in California.

Nationally, the number of coronavirus cases surpassed 500.

There are no confirmed cases in Alabama.

Italy reports 133 deaths

The death toll in Italy, the European country hardest hit by coronavirus, has reported 133 deaths.

The number of cases in Italy rose from 5,883 to 7.375 over the weekend. At least 622 people have recovered from the virus, with most of the deaths occurring in those older than the age of 50 who contracted the virus.

More than 16 million people in Italy – roughly a quarter of the country’s population – are under lockdown.

Surgeon general: Don’t panic

U.S. Surgeon General Dr. Jerome Adams said Americans should prepare for – but not panic about – coronavirus.

Speaking on CNN’s “State of the Union,” that the U.S. had a “posture of containment so that we could give people time to prepare for where we are right now.”

“Now, we're shifting into a mitigation phase, which means we’re helping communities understand, you're going to see more cases. Unfortunately, you're going to see more deaths, but that doesn’t mean that we should panic.”

Adams urged people to “do the things that we know work for individuals to protect themselves," such as washing their hands frequently, covering their coughs and staying home if they're sick.

Florida school closes

A school in Niceville, Florida will close Monday through Spring Break due to a confirmed case of COVID-19 at a local church attended by some of the students.

Rocky Bayou Christian School is voluntarily closing the week leading up to spring break, allowing for a 14-day incubation period as advised by the CDC. Schools will resume normal operations March 23.

Here is more on coronavirus from AL.com:

Alabama airports scrubbing and sanitizing to stay ahead of coronavirus

SEC, SEC Network closely monitoring coronavirus situation ahead of SEC Tournament

Coronavirus concerns: Don’t travel on cruise ships, US State Department warns

For complete AL.com coverage, go here.