A Perth taxi driver who sexually and indecently assaulted five wheelchair-bound women in his vehicle has been jailed for 10 years.

Peter Edward Kasatchkow, 58, was sentenced in the Perth District Court on Friday over 33 offences including indecently dealing with an incapable person and sexual penetration without consent.

The incidents happened on separate occasions when the women, aged between 18 and 52, were passengers in his taxi between January and February this year.

Some of the victims had cerebral palsy and multiple sclerosis, with some unable to communicate and requiring constant care.

In one incident, Kasatchkow kissed a 29-year-old victim's breasts and mouth, and sexually penetrated her despite the woman repeatedly telling him to stop.