The driver of a transport truck has been sent to hospital after colliding with a van on Highway 401, Ontario Provincial Police say.

The driver suffered critical injuries and had no vital signs when paramedics arrived, Sgt Kerry Schmidt said on Twitter.

The collision happened between Whites and Brock Roads. Eastbound express lanes remain closed as police investigate, and traffic will be diverted into the collector lanes instead.

The two people in the van were not injured, Schmidt said.