A serial killer who says he has murdered at least 90 women was given two life sentences, in addition to the three he is already serving, after pleading guilty to strangling two women to death in Ohio.

On Friday, Samuel Little, 79, confessed to the killing of Cincinnati woman Anna Stewart and another unidentified woman on the condition that prosecutors would not seek the death penalty.

Little appeared via Skype from California state prison, where he's already serving life sentences for three murders.

Hamilton County Judge Melba Marsh said the new sentences, of 15 years to life for each crime, will run consecutively in addition to the time he is already serving in California, according to WCPO.

Little, who is believed to be America's most prolific serial killer, appeared frail as he appeared via Skype link from California State Prison on Friday.

He was charged with the 1981 murder of 32-year-old Anna Stewart, a mother of three who was last seen alive in Cincinnati.

Samuel Little, (pictured), who has confessed to over 90 murders, was given two life sentences murdering two women in Cincinnati in court on Friday

Little, who is believed to be America's most prolific serial killer, appeared frail as he appeared via Skype link from California State Prison for sentencing for the murders of two women

She was strangled in October 1981 and her body was dumped in Grove City, near Columbus, The Cincinnati Enquirer reported.

Little told investigators it was raining, so he drove her body to Grove City outside Columbus and dumped her in a wooded area near a small apartment complex.

In the second case, the victim's name is not known, and he is expected to plead guilty to killing a 'Jane Doe,' Hamilton County Prosecutor Joe Deters said.

Deters claimed this will be allowed as long as there is no objection from Little’s attorneys, according to The Cincinnati Enquirer.

Officials say the woman was killed between 1980 and 1999 and that her body may have been found within a 20-minute drive of Over-the-Rhine.

Investigators say that he targeted vulnerable women and strangled them for sexual pleasure.

Officials have allowed Little to sketch portraits of his victims and released dozens of the drawings to the media.

He has made two of the 'girl by highway,' who officials believe is the unidentified Cincinnati victim.

Common Pleas Judge Melba Marsh will oversee the videoconferencing of the plea hearing and sentence from the Hamilton County Courthouse library.

The arrangements were made because Little’s 'health does not permit him to travel back to Ohio to face this felony indictment,' court documents state.

Hamilton County Judge Melba Marsh said the sentences, of 15 years to life for each murder, will run consecutive to each other and to the time he is already serving in California

Little, who lived a nomadic lifestyle, claims to have killed 93 women as he crisscrossed the country over the years. He is pictured in 2014 following his conviction for three murders

Little was convicted of killing three women in the Los Angeles area and pleaded guilty to killing a Texas woman.

Little, who lived a nomadic lifestyle, claims to have killed 93 women as he crisscrossed the country over the years, which would make him the most prolific serial killer in U.S. history.

An FBI profile on him claimed: 'Little’s run-ins with the law date back to 1956, and there are clear signs of a dark, violent streak among his many shoplifting, fraud, drug, solicitation, and breaking and entering charges.

'But law enforcement has only recently begun unraveling the true extent of his crimes.'

He was arrested in September 2012 at a Louisville homeless shelter and extradited to California, where he was wanted on a drug charge.

Little was convicted of the 1989 murder of Audrey Nelson, 35 (left), in Los Angeles in 2014. The cold case of the 1982 murder of Rosie Hill, 20 (right), in Ocala, Florida was closed on November 15 following Little's confession to the slaying

Pearl Nelson (left) is shown holding a photo of her mother, victim Audrey Nelson, as she is hugged by Mary Louise Frias, (right), whose godmother Guadalupe Apodaca Zambrano, was also a victim of convicted serial killer Little

DNA connected Little to victims in three unsolved Los Angeles murders of Carol Elford, Guadalupe Abodaca and Audrey Nelson from 1987 and 1989.

All three women had been beaten and strangled and their bodies were dumped in an alley, a dumpster, and a garage.

Little asserted his innocence throughout his trial, even as a string of women testifying for the prosecution told of narrowly surviving similarly violent encounters with Little.

He was convicted and sentenced to three consecutive life sentences with no possibility of parole.

Texas Ranger James Holland traveled to California last year to speak with Little about cold cases in Texas after the killer opened up to him,

That led Little to be extradited to Texas and his guilty plea in December in the 1994 strangulation death of Denise Christie Brothers in the West Texas city of Odessa.

Officials have allowed Little to sketch portraits of his victims and they released dozens of the drawings to the media due as many of the killings took place decades ago

The FBI claimed that Little, a one-time competitive boxer, usually stunned or knocked out his victims with powerful punches and then strangled them. He is pictured last November

Holland’s conversations with Little continued, even after Little was returned to California to serve his sentences.

It was Holland who determined that he was responsible for 93 deaths, said Ector County District Attorney Bobby Bland, who received an update from Holland in June this year.

Information provided to Holland was relayed to law enforcement agencies in several states, leading to a revolving door of investigators who traveled to California to corroborate decades-old deaths.

Among them were investigators from Ohio, where prosecutors announced the charges in the deaths of the two Cincinnati women.

The FBI claimed that Little, a one-time competitive boxer usually stunned or knocked out his victims with powerful punches and then strangled them.

With no stab marks or bullet wounds, many of the deaths were not classified as homicides but attributed to drug overdoses, accidents, or natural causes.

DNA evidence was often not available or could not provide a clear link back to Little. A large number of the killings occurred in the 1970s and early 1980s, before DNA profiling was part of standard law enforcement.

After DNA analysis came into play, the victims’ work as prostitutes complicated the ability of police to gather telling physical evidence.