Residents are being airlifted out of southern Queensland's interior as floodwaters creep to record levels.

Half of the houses in the town of Mitchell, east of Charleville, have been affected by a major flood peak in the Maranoa River.

Helicopter and swift water rescue crews have helped people evacuate their homes at Mitchell in Queensland's flooded southern inland.

Authorities say more than 270 people have had to leave their homes in Mitchell as the floodwaters continue to rise.

Overnight a second evacuation centre was set up after road access to the first was cut.

A state disaster management committee meeting has been held this morning.

Mitchell disaster coordinator Roger White says he expects more people to use the evacuation centre today as there is more water on the way.

"The extent of this flood is off this planet - it hasn't been seen before within the Mitchell area," he said.

"There is still some more water to come to Mitchell, so I stress to all people living within the Mitchell township to go to the school on Cambridge Street where you will be looked after."

Mitchell resident Gary Burkett says the floodwaters have separated him from his wife.

"Hopefully I'd like to get back to my wife and I can't cross the river - I'm on one side and she's on the other," he said.

"Come into work and beat the flood over the river at 5:30 yesterday morning and I haven't been able to get back home."

Roma

Emergency Services Minister Neil Roberts saying homes in low-lying parts of Roma are now also being evacuated.

"We're looking at a potential rise to around 8.1 metres, which is equivalent to the March 2010 floods," he said.

All schools in both Mitchell and Roma are closed today.

Floodwaters are also rising at Surat to the south.

Extra police have been sent to St George and Dirranbandi and more State Emergency Service (SES) workers have gone to Roma.

Maranoa Mayor Robert Loughnan says he is worried.

"[The Maranoa River] is rising very rapidly - a major concern for us and of course the rainfalls exacerbate those problems," he south.

Weather bureau senior forecaster Brett Harrison says the situation is not expected to improve anytime soon.

"Roma and the river there is expected to peak later on today," he said.

"A lot of those warnings are being updated at the moment by the hydrologists because of the increased rainfall overnight.

"We do expect the river levels to get to very high levels and there's even a possibility of some records being broken."

St George

Further south, St George is ramping up preparations for its third big flood peak in three years.

The weather bureau now says the Balonne River near St George could rise higher than the March 2010 peak of 13.4 metres.

St George residents will feel the force of the floods next week.

Balonne Mayor Donna Stewart says the predicted peak will test the town's levee, which can be raised to 14.5 metres.

Councillor Stewart says moats that stopped some homes from being swamped last year may need to be rebuilt, along with a temporary levee.

"We'll be having another look at that today and considering what our next action is as we get further information," he said.

"I suppose the good part about it down here is that we do get some warning."

Authorities in St George are considering whether to evacuate the local nursing home.

Councillor Stewart says if the Balonne River goes higher than the 2010 peak, water will start to go into the nursing home.

She says elderly residents have been flown to Brisbane during the past two floods.

Charleville

Meanwhile in Charleville, authorities have erected a temporary levee and are expecting to install flood gates on the rising Warrego River later today.

Residents have been threatened twice this week by Bradley's Gully, which run through Charleville, but now the river is expected to rise to major flood levels of around seven metres.

About 10 people spent the night again in the town's evacuation centre.

Murweh Mayor Mark O'Brien says the rising floodwaters will not cause major issues for the town, but will cut the Mitchell Highway.

"Seven metres is what they call a major flood but it certainly isn't going to threaten the community here - the levee bank is a fair bit higher than that.

"It looks like everything may have just fallen nicely for us at this stage.

"[Bradley's] Gully might clear up and dry up for us over the next couple of days and we'll get a good, strong run in the river."

"We took a fire unit and an ambulance unit across [the river] on a low-loader, so we have both those emergency units in place over that side of the river.

"There is a manned SES rescue boat at Gowrie Crossing, so if anyone does have an emergency and needs to get across the river either way we can do that.