Perpetrators of sexual assault are often intoxicated; however, few experimental studies evaluate alcohol's “in the moment” effects on sexual aggression. This study extends past theory and research by examining the acute effects of alcohol on men's decisions about how to respond to sexual refusals in a dating simulation. Men (N = 62) ages 21–29 were randomly assigned to consume alcohol (target breath alcohol level 0.080%) or no alcohol. Participants were encouraged to talk to a simulated woman and act as they would on an actual date. They made choices from a list which included nonsexual and sexual options. The female agent was programmed to engage in some sexual activities but refuse others. Refusals became more intense if participants persisted. Negative binomial regression analysis was used to test a path analytic model. As predicted, participants' self‐reported desire to have sex was positively associated with choosing more consensual sexual activities during the simulation (i.e., activities in which the woman willingly engaged). Consensual sexual activities were positively associated with the number of times participants persisted after the woman refused. Alcohol moderated this relationship such that it was stronger for intoxicated men than sober men. The more sexual refusals participants received, the more hostile verbal comments they made to the woman. Contrary to our predictions, this relationship was not moderated by alcohol condition. Because participants had multiple opportunities to escalate their aggression or desist, this paradigm provides new insights into the mechanisms through which intoxication enhances the likelihood of sexual aggression in dating situations.