The Detroit Lions will try and stop the NFL's best offense without their No. 1 cornerback.

Darius Slay is inactive for today's game against the Kansas City Chiefs after pulling his right hamstring in last week's win over the Philadelphia Eagles.

Slay is one of three key defensive players who will not play for the Lions today.

Defensive tackles Mike Daniels and Da'Shawn Hand also are inactive with foot and elbow injuries, respectively. Daniels is out indefinitely after spraining his foot last week, while Hand has not played since injuring his elbow in the first week of training camp.

Wide receiver Danny Amendola (chest) also is inactive for the Lions, while quarterback Matthew Stafford will make his 132nd consecutive start after he was listed as questionable with a hip injury on the Lions' Friday injury report.

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Stafford, ESPN reported, dealt with increasing pain in his hip as the week went on. He has not taken a sack in the last two games and was in good spirits as he talked to a reporter Friday after practice, but he dealt with a painful back injury late last year.

The Lions kept two backup quarterbacks, David Blough and Jeff Driskel, active for the first time this year.

Defensively, Mike Ford is expected to start at cornerback in place of Slay, a two-time Pro Bowler who has 12 interceptions since the start of the 2017 season.

The Chiefs, led by reigning MVP quarterback Patrick Mahomes, had one of the highest-scoring offenses in NFL history last season and lead the NFL in passing (392.3 ypg) by a wide margin entering today's game.

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With Daniels and Hand out, the Lions have just five active defensive linemen: Trey Flowers, Romeo Okwara, Damon Harrison, A'Shawn Robinson and Kevin Strong.

The Chiefs are without their No. 1 receiver (Tyreek Hill), left tackle (Eric Fisher) and starting running back (Damien Williams) because of injury.

Contact Dave Birkett at dbirkett@freepress.com. Follow him on Twitter @davebirkett. Read more on the Detroit Lions and sign up for our Lions newsletter.