A Sydney neurosurgeon has been been jailed for five years over the deaths of two prostitutes during cocaine and sex sessions.

Suresh Nair pleaded guilty to the 2009 manslaughter of Suellen Domingues Zaupa and to supplying cocaine to another escort, Victoria McIntyre.

Both women died from cocaine toxicity at his exclusive Elizabeth Bay unit, in Sydney's inner east, in separate drug and sex sessions.

Nair, 43, also pleaded guilty to a charge of supplying a prohibited drug while on bail.

In the New South Wales District Court today, Nair was sentenced to five years and three months in jail.

He will be eligible for parole in 2015.

Justice Robert Toner referred to the depths to which Nair had "fallen".

He noted that Nair had shown remorse and has a permanent eye injury after being bashed in jail, but also said Nair was negligent and self-indulgent.

"The offender displayed a determined persistence in abusing cocaine," Justice Toner said.

The judge also noted Nair had breached his original bail conditions by using cocaine and hiring prostitutes, even though he was banned from doing so.

During his committal hearing the New South Wales District Court was told Nair often booked more than two escorts a night, then snorted and smoked cocaine with them for hours.

The court heard on the night Ms Zaupa died, Nair agreed to pay her and another escort $26,000 each to have group sex with him.

Ms Zaupa was struggling to breathe when she died as Nair and the other escort watched.

The court heard that despite his medical training, Nair did not call an ambulance when Ms Zaupa was having convulsions.

The surgeon had been suspended from his job at Nepean Hospital, in Sydney's west, three times since 2004.

He had been regularly tested for drugs and in 2008 a complaint about his clinical practice was referred to the New South Wales Medical Board.

It is understood other complaints have been made against him by patients he has operated on.