It was a tough night for Arsenal’s South American contingent in World Cup qualifiers as David Ospina seemingly picked up another injury for his national side.

Colombia ran out 3-2 winners in a tough visit to Bolivia, with only a last minute goal from substitute Edwin Cardona securing the three points for Jose Pekerman’s side, moving them with a point of automatic qualification for Russia 2018.

Ospina, who conceded twice to allow Bolivia back into the match after James Rodriguez and Carlos Bacca had struck early for the visitors, went down painfully after catching an opponent whilst looking to punch a cross clear.

Although the Arsenal keeper, who has been in impressive form during Petr Cech’s absence from his club side, managed to play on for the remainder of the 90 minutes he was helped off the pitch at full time.

The 27-year-old had injured his back in his last game for Arsenal, colliding with Romelu Lukaku in a 2-0 victory over Everton.

Arsene Wenger expressed his confidence that Petr Cech would be available after the international break earlier this month. However were both senior goalkeepers to be available 21-year-old Matt Macey, who signed a new contract this week, could be drafted in.

Arsenal’s other South American star endured a frustrating night as Alexis Sanchez struggled through Chile’s 2-1 defeat to Argentina in Santiago.

In Juan Antonio Pizzi’s first game at the Chile helm Felipe Gutierrez headed the hosts into an early lead but goals from Angel di Maria and River Plate’s Gabriel Mercado secured a comeback victory for Argentina.

Sanchez struggled to make a major impact on the game, his only notable moment coming when he fired a late free-kick over.