People have been asked to keep an eye out for a single Asian honey queen bee that could cause an agricultural catastrophe.

The bee was part of a swarm of Asian honey bees found in the foot well of a campervan travelling from Cairns to Darwin but is now suspected of being in the Top End of Australia's Northern Territory.

Asian honey bees are considered to be pests and can potentially cause agricultural disasters by sucking blood from other bees and killing them due to a disease they sometimes carry called varroa mite.

A single Asian honey queen bee is on the loose in the Top End of the Northern Territory

The majority of the swarm were quickly contained, killed and checked for varroa mite which returned a negative result.

However the queen bee of the pack was nowhere to be found and the Northern Territory Department of Primary Industry and Fisheries say they need to find her before she starts up another potentially dangerous colony.

Speaking to the ABC Stephen West, chief plant health manager for the Northern Territory Department of Primary Industry and Fisheries, likened the quest to searching for a needle in a haystack but was unsure if she would survive without her swarm.

'It's a matter of how that journey went for the queen, what condition she was in when they arrived, and that swarm that's moved off with her, the strength of those bees as well, and how quickly they can find a food source,' he said.

The majority of the swarm were quickly contained, killed and checked for varroa mite which returned a negative result

Mr West said the Asian honey bees are more aggressive than European bees and because they are disease carriers they need to be caught and killed immediately

'If she's here we need to find her and we need to eradicate her. We need to do it as quickly as we can.

'If people notice any bee activity at all they should call because they really need to know if there’s another outbreak of Asian Honey bees.'

Mr West said the Asian honey bees are more aggressive than European bees and because they are disease carriers they need to be caught and killed immediately.