A conservative revolt is threatening to derail an ObamaCare repeal bill that Republicans had hoped to send to President Obama’s desk.

The House on Friday is expected to pass the long-awaited legislation, which would demolish major pillars of ObamaCare and — under the rules of reconciliation — bypass a Democratic filibuster in the Senate.

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But a small core of conservatives in both chambers, led by presidential candidate Sen. Ted Cruz Rafael (Ted) Edward CruzTrump argues full Supreme Court needed to settle potential election disputes Press: Notorious RBG vs Notorious GOP The Hill's Morning Report - Sponsored by Facebook - Washington on edge amid SCOTUS vacancy MORE (R-Texas), are upset that the legislation doesn’t repeal ObamaCare root and branch. They say GOP leaders need to pursue full repeal and stand up against the one obstacle that appears to be in their way: the Senate parliamentarian.

“In some cases, I think the Senate is being a little too deferential to the parliamentarian, and I think it’s time for the leadership of the Senate to stand up to the parliamentarian,” Rep. Bill Flores William (Bill) Hose FloresPatient Protection Pledge offers price transparency Texas GOP lawmaker calls for 'carbon neutral' but 'energy dominant' future OVERNIGHT ENERGY: Biden calls climate change one of America's four major crises | National parks chief says coronavirus staff shortages shouldn't prevent access | Trump hits California officials over wildfires MORE (R-Texas), chairman of the Republican Study Committee, said Thursday. He said he is still deciding how to vote on Friday’s bill.

While the bill is expected to clear the House with little conservative opposition, its prospects are less certain in the Senate.

Cruz announced late Thursday that he — along with Sens. Mike Lee Michael (Mike) Shumway LeeMcConnell shores up GOP support for coronavirus package McConnell tries to unify GOP Davis: The Hall of Shame for GOP senators who remain silent on Donald Trump MORE (R-Utah) and Marco Rubio Marco Antonio RubioOvernight Defense: Pentagon redirects pandemic funding to defense contractors | US planning for full Afghanistan withdrawal by May | Anti-Trump GOP group puts ads in military papers Democrats step up hardball tactics as Supreme Court fight heats up Press: Notorious RBG vs Notorious GOP MORE (R-Fla.), another presidential candidate — would oppose any partial repeal of ObamaCare through reconciliation.

“At the end of the day, the Senate parliamentarian is an employee of the Senate. Virtually every Republican campaigned promising full repeal,” Cruz told The Hill on Thursday.

With the three senators now declared against the bill, Senate Majority Leader Mitch McConnell Addison (Mitch) Mitchell McConnellPelosi: Trump hurrying to fill SCOTUS seat so he can repeal ObamaCare Senate GOP aims to confirm Trump court pick by Oct. 29: report Trump argues full Supreme Court needed to settle potential election disputes MORE (R-Ky.) will have to keep the rest of his 54-member caucus united to secure the 51 votes needed for passage.

That could be a tall order.

Already, three Senate Republican have voiced opposition to a provision in the reconciliation bill that would halt federal funding for Planned Parenthood, including Sen. Mark Kirk Mark Steven KirkLiberal veterans group urges Biden to name Duckworth VP On the Trail: Senate GOP hopefuls tie themselves to Trump Biden campaign releases video to explain 'what really happened in Ukraine' MORE (R), who is up for reelection next year in blue-leaning Illinois.

With the 46 members of the Senate Democratic caucus expected to vote in lockstep against the legislation, Republicans will have little margin for error.

Republicans had touted the reconciliation process as a way to make Obama answer for his healthcare law, so failing to pass the legislation would be a setback.

The conservative complaints center on the Senate’s Byrd Rule, which states that a reconciliation bill can only include provisions that have a direct impact on the budget. The decision about whether the legislation meets that standard is made by Parliamentarian Elizabeth MacDonough, an appointee of Senate GOP leadership.

Flores and others say Republican leaders are not taking a strong enough stance against MacDonough and the decades-old Senate procedures that she governs.

While current Senate rules wouldn’t allow a full repeal, Flores said the Senate parliamentarian could be overruled.

“If you read the Senate rules, there are provisions where the Senate parliamentarian can be overridden,” Flores said, adding, “There are some of us that have concerns because it is a very, very modest reconciliation.”

Rep. Joe Pitts (R-Pa.) said that while he also has concerns about the limited scope of the reconciliation bill, he supports it because it defunds Planned Parenthood for one year. He said the fight over Senate procedure should be handled by members of that chamber.

“I don’t think there’s any reason why Sen. Cruz or Lee or any other senators can’t just do amendments in the Senate to take it as far as they can take it,” Pitts said.

GOP leaders have spent months shaping a reconciliation bill that would roll back major pieces of ObamaCare while following the complex — and sometimes subjective — Senate rules.

Among other things, the legislation would repeal several taxes in ObamaCare and nullify the individual and employer mandates for health insurance.

Outside groups such as the conservative Heritage Action for America and the libertarian Cato Institute have pushed back against the package, arguing it should be replaced with full repeal. They say that, since ObamaCare can be considered a federal program, everything in the healthcare law is budget related.

Heritage Action plans to hold a “key vote” on the reconciliation bill, with a vote in favor of the bill working against the group’s scoring of a lawmaker’s record.

Despite pressure from outside conservative groups, no House Republicans have publicly said they would vote against the bill.

Some Republicans are pushing back against their colleagues’ claims that the Senate parliamentarian is to blame.

“I have more respect for the parliamentarian than any of my colleagues. With that said, they have no power there. Whenever they tell you, ‘Oh the parliamentarian is making us do this or that,' or something, hogwash,” Rep. Thomas Massie (R-Ky.) told The Hill on Thursday.

“It’s a pretend vote and people are upset because it doesn’t pretend enough. I’ll vote for it,” he said.

The House Freedom Caucus also plans to back the reconciliation bill, according to one member, Rep. John Fleming John Calvin FlemingTrump wants Congress to delay Census deadlines amid pandemic Meadows sets up coronavirus hotline for members of Congress The Hill's Morning Report - Iran strikes US bases in Iraq; Trump to speak today MORE (R-La.).

“It certainly would be a step in the right direction, so this will be the closest we can come in actually getting it to the president's desk,” he said.

- Peter Sullivan contributed