Former federal Liberal MP Sophie Mirabella has been escorted from a lecture at Melbourne University after it was apparently overrun by protesters.

Mobile phone footage shows Ms Mirabella being guided out of the room while people chant.

They appear to be protesting against recent changes to higher education that could result in students paying higher fees and greater interest on loans for their degrees.

The university's computer system was also hijacked with photos of Margaret Thatcher loaded on the screens.