Blood drenched the city’s streets Saturday night into Sunday during the deadliest spate of shootings since Mayor Bill de Blasio took office.

The relentless gunfire over a period of less than 12 hours claimed the lives of three people and wounded a dozen more.

The rash of gun violence came after a week in which the NYPD admitted that shootings are up and said it’s looking into whether that’s because of the decline in the use of stop-and-frisk.

Gun-toting thugs “are taking chances because they don’t think stop-and-frisk is going on,” fumed state Sen. Martin Golden (R-Brooklyn) on Sunday. “Thank God these guys are bad shots and thank God for our trauma rooms that keep these [victims] alive.

“If we don’t do stop-and-frisk, there will be more shootings and there will be more death.”

The mayhem, which hit all five boroughs, marked the third June weekend in which more than a dozen victims were shot, a trend that has city dwellers fearing a long, bloody summer.

“This is the worst time of the year. Once it gets hot out, people lose their minds,” Dika Robbins, 28, said Sunday afternoon at Manhattan’s Harlem River Park, where four people were shot around 1:50 a.m. Sunday.

De Blasio ignored questions about the rash of shootings after walking in Sunday’s LGBT Pride March on Fifth Avenue wearing a wide rainbow tie.

NYPD Commissioner Bill Bratton noted to reporters around noon that there had been 23 shootings since June 23, compared with 37 between June 16 and 22.

The weekend’s dead included Jason Bragg, 33, who was found sprawled in the street in the St. Albans section of Queens around 10:20 p.m. Saturday.

Bragg’s uncle Keith, 59, who lives near the shooting scene, said his nephew, a married father of two young girls, “was just coming to see me and spend some time with the family.”

“I don’t know why he got shot,” he said.

Also killed was Roderick Romney, 24, who was found shot in the stomach on University Avenue in The Bronx at 4:59 a.m. Police later arrested Jason Delgado, 29.

Another victim of the weekend’s gunfire included a 10-year-old boy who was shot in the right knee about two blocks from the Coney Island boardwalk around 7:20 p.m. Saturday.

In a statement, de Blasio spokesman Phil Walzak said, “The mayor and the Police Department are working closely to put hundreds of more officers on the streets, deploy cops to areas experiencing crime spikes, and utilize innovative strategies to catch bad guys and keep neighborhoods safe.”

Additional reporting by Aaron Short, Kenneth Garger and Antonio Antenucci