Britain will rejoin the EU once a “new generation” that is less hostile to Europe takes charge, the European parliament’s Brexit chief has said.

Guy Verhofstadt said he believed the UK would one day come back to “the great European family”, despite its looming departure.

He made the prediction in a debate of MEPs about the withdrawal agreement, in which chief negotiator Michel Barnier reaffirmed that “this deal is the only one and the best possible” for the UK.

Mr Verhofstadt told the parliament: “Let me make clear that in this process there are no winners. The departure of the UK from the European Union is a failure for everybody, for the UK, as for the EU.

“Last Sunday was a sad day for both. So let us make the best of it, in the knowledge that once, in the near future there will be a new generation in Britain who will decide to come back into the great European family.”

Polls and studies suggest that young people were significantly more likely to vote Remain than the older generation.

Other senior MEPs speaking during the debate backed the deal. Elmar Brok, a German MEP from Angela Merkel’s Christian Democratic Union, warned Remainers in the UK that they would be taking a risk by rejecting the plan.

“If there is no treaty then there will be no transitional period and it’s going to be an abrupt break,” he said.

“It must be made clear that it is a very risky initiative for the Remainers, rejecting this and hoping something else is going to come, like a referendum – that’s a very risky business.”

He added that the EU had “got the best deal possible”, adding: “Brexit is a very bad affair for the European Union and Great Britain – more for Great Britain, given its size, but it’s also a very bad thing for us as well.”

Philippe Lamberts, a Green MEP who sits on the parliament’s Brexit steering group, said “no other Brexit is available” and that a no-deal Brexit would “make the UK a rogue state, a country whose signature with any other partner would amount to just nothing”.

“The real choice is between Brexit under the terms negotiated and no Brexit at all,” he said, adding that the EU should allow Britain to stay in if it wanted to.

Nigel Farage said negotiations were ‘game, set, and match’ to Michel Barnier (EbS)

Former Ukip leader Nigel Farage said: “I’m in no doubt that this withdrawal agreement is a good deal … it’s a good deal for the European Union. For the UK I think it’s probably the worst deal in history.

“Mr Barnier, I have to say to you: I wish you were on our side, really. Because it’s game set and match to you. You probably can’t even believe your luck that you came up against a British prime minister who met every single demand of yours while at the same time trying to deceive the British public.”

Mr Barnier, the EU’s chief negotiator, echoed his message from Sunday’s European Council summit to MEPs.

A historic moment: thousands march to demand Final Say on Brexit Show all 65 1 /65 A historic moment: thousands march to demand Final Say on Brexit A historic moment: thousands march to demand Final Say on Brexit An estimated 700,000 people marched through London to demand a final say on the withdrawal agreement Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Red smoke from a canister hangs in the air as around 100,000 demonstrators march through London during a People's Vote anti-brexit demonstration savings banners and placards Anti-Brexit People's Vote March for the Future in London Rex A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Mayor of London Sadiq Khan takes part in the People's Vote March for the Future in London, a march and rally in support of a second EU referendum. PA A historic moment: thousands march to demand Final Say on Brexit Final Say campaigners take part in the peoples vote march for the future in London 20/10/2018 Protesters wearing final Say shirts and holding placards Angela Christofilou A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final say Brexit march - final say on our furture London, 20 October 2018 Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit MP Chuka Umunna (left) and MP Vince Cable (right) as MP Anna Soubry (centre) addresses Anti-Brexit campaigners at a rally after the People's Vote March for the Future in London, a march and rally in support of a second EU referendum. PA A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit A People’s Vote march attendee calls for a Final Say Angela Christofilou A historic moment: thousands march to demand Final Say on Brexit Demonstrators with banners 'We're with EU' during the People's Vote March for the Future in London, Britain, 20 October 2018. Reports state that the 'March for the Future' is to be led by a column of young people and call for a Peopleâ€™s Vote on the Brexit deal. After marching through central London, there will be a rally on stage in Parliament Square, including speeches from Mayor of London Sadiq Khan. EPA A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Protesters at London’s march for the future in October The Independent A historic moment: thousands march to demand Final Say on Brexit Editor of The Independent Christian Broughton speaks to demonstrators in Parliament Sqaure after they take part in a march calling for a People's Vote on the final Brexit deal, in central London on October 20, 2018. - Britons dreading life outside Europe gathered from all corners of the UK to London on Saturday to try to stop their country's looming breakup with the EU. AFP/Getty A historic moment: thousands march to demand Final Say on Brexit A poster at the March for the Future in October The Independent A historic moment: thousands march to demand Final Say on Brexit Anti-Brexit campaigners take part in the People's Vote March for the Future in London, a march and rally in support of a second EU referendum. PA A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say campaigners take part in the peoples vote march for the future in London 20/10/2018 Angela Christofilou A historic moment: thousands march to demand Final Say on Brexit Final say Brexit march - final say on our furture London, 20 October 2018 Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final say Brexit march - final say on our furture London, 20 October 2018 Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Anti-Brexit campaigners take part in the People's Vote March for the Future in London, a march and rally in support of a second EU referendum. PA A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final say Brexit march - final say on our furture London, 20 October 2018 Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Demonstrators hold placards as they take part in a march calling for a People's Vote on the final Brexit deal, in central London on October 20, 2018. - Britons dreading life outside Europe gathered from all corners of the UK to London on Saturday to try to stop their country's looming breakup with the EU. AFP/Getty A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final say Brexit march - final say on our furture London, 20 October 2018 Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final say Brexit march - final say on our furture London, 20 October 2018 Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou A historic moment: thousands march to demand Final Say on Brexit Final say Brexit march - final say on our furture London, 20 October 2018 Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final say Brexit march - final say on our furture London, 20 October 2018 Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final say Brexit march - final say on our furture London, 20 October 2018 Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final say Brexit march - final say on our furture London, 20 October 2018 Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou A historic moment: thousands march to demand Final Say on Brexit Final Say campaigners take part in the peoples vote march for the future in London 20/10/2018 campaigner wrapped in EU flag Angela Christofilou A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say march for the future London, 20 October 2018 Credit: Angela Christofilou/The Independent Angela Christofilou/The Independent Angela Christofilou/The Independent A historic moment: thousands march to demand Final Say on Brexit Final Say campaigners take part in the peoples vote march for the future in London 20/10/2018 Angela Christofilou A historic moment: thousands march to demand Final Say on Brexit Demonstrators pass Trafalgar Square as they take part in a march calling for a People's Vote on the final Brexit deal, in central London on October 20, 2018. - Britons dreading life outside Europe gathered from all corners of the UK to London on Saturday to try to stop their country's looming breakup with the EU. AFP/Getty A historic moment: thousands march to demand Final Say on Brexit Demonstrators wave Union and European flags and hold up placards as they pass Trafalgar Square, taking part in a march calling for a People's Vote on the final Brexit deal, in central London on October 20, 2018. - Britons dreading life outside Europe gathered from all corners of the UK to London on Saturday to try to stop their country's looming breakup with the EU. AFP/Getty A historic moment: thousands march to demand Final Say on Brexit Demonstrators hold placards as they take part in a march calling for a People's Vote on the final Brexit deal, in central London on October 20, 2018. - Britons dreading life outside Europe gathered from all corners of the UK to London on Saturday to try to stop their country's looming breakup with the EU. AFP/Getty A historic moment: thousands march to demand Final Say on Brexit A demonstrator holds a message during a march calling for a People's Vote on the final Brexit deal, in central London on October 20, 2018. - Britons dreading life outside Europe gathered from all corners of the UK to London on Saturday to try to stop their country's looming breakup with the EU. AFP/Getty A historic moment: thousands march to demand Final Say on Brexit Anti-Brexit campaigners take part in the People's Vote March for the Future in London, a march and rally in support of a second EU referendum. PA A historic moment: thousands march to demand Final Say on Brexit Demonstrators take part in the 'People's Vote March for the Future,' in central London, Britain, 20 October 2018. Reports state that the 'March for the Future' is to be led by a column of young people and call for a Peopleâ€™s Vote on the Brexit deal. After marching through central London, there will be a rally on stage in Parliament Square, including speeches from Mayor of London Sadiq Khan EPA A historic moment: thousands march to demand Final Say on Brexit A protester brandishes an Independent t-shirt during the Brexit March Angela Christofilou A historic moment: thousands march to demand Final Say on Brexit Anti-Brexit campaigners take part in the People's Vote March for the Future in London, a march and rally in support of a second EU referendum PA A historic moment: thousands march to demand Final Say on Brexit Tens of thousands of people take part in People's Vote March for the Future in central London. The march organised by the People's Vote campaign is led by young people calling for a People's Vote on the Brexit deal Rex A historic moment: thousands march to demand Final Say on Brexit Anti-Brexit campaigners take part in the People's Vote March for the Future in London, a march and rally in support of a second EU referendum PA

“Given the difficult circumstances of this negotiation and given the extreme complexity of all the issues of the British withdrawal, the deal that is on the table ... this deal is the only one and the best possible,” Mr Barnier said. “Now is the time for ratification.”

He added: “It’s not a question of winners and losers because Brexit is a lose-lose. There is no added value.”