USA TODAY Sports

Week 6 of the NFL season begins Thursday night as the Denver Broncos attempt to rebound from their first loss by trying to hand the reeling San Diego Diego Chargers their 11th consecutive AFC West defeat.

Sunday's action will feature the return of San Francisco 49ers quarterback Colin Kaepernick to the starting lineup and Tom Brady's first game in front of the New England faithful since his Deflategate suspension ended last week.

But the weekend's premier matchup would seem to be the Atlanta Falcons and their top-ranked offense pairing off with the Seattle Seahawks and their No. 1 defense, which has only allowed one passing touchdown all season.

PHOTOS: Week 6 games ranked by watchability