(CNN) Presidential hopeful Sen. Kamala Harris said Tuesday that the Trump administration is "playing politics, yet again" with the Affordable Care Act, calling it the "height of irresponsibility."

The California Democrat told CNN's Wolf Blitzer on "The Situation Room" that "the idea that we would turn the clock back because of some political purpose instead of prioritizing public health is irresponsible," and added, "We're going to have to fight against it again."

The Trump administration, in a dramatic reversal, said Monday that the entire Affordable Care Act should be struck down . The Justice Department said in a filing with a federal appeals court that it agreed with the ruling of a federal judge in Texas that invalidated the Obama-era health care law.

Harris joins other 2020 Democrats in slamming the move by the administration and rallying around the Affordable Care Act.

The senator said health care is an issue that "keeps most Americans up at night, regardless of who they vote for," as they worry about whether they can afford it.

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