There are the obvious reasons, not the least of which is her place in the history books as the first female House speaker.

But it is more than that. It is how she got there -- excelling in a man's world and playing in what was traditionally a boy's club of politics -- as well as, and often better than, her male counterparts.

She's had plenty of detractors and naysayers, even among Democrats. But she is seen as effective, so much so that even her political opponents -- mostly men -- have repeatedly told me over the years that they marvel at her leadership of her caucus.

For all the interviews Pelosi does, she doesn't talk often about her struggles and challenges as a woman. But here, she spoke quite candidly about it all.

"I get some names called, because if you're effective as a woman, then they have to undermine you, because that's a real threat," Pelosi told us in an interview.

"I'm probably more of a target than anybody, except for somebody who runs for president," she said.

Talk about an understatement. For years Pelosi has been the ultimate Republican boogeyman -- or boogeywoman, as it were. She's a frequent target of Republican ire for being too far to the left -- and she's also a target among progressives for not being far left enough.

Some fellow Democrats are now distancing themselves from Pelosi, promising not to vote for her as House speaker again even though her party has won a majority in the House of Representatives in the midterm elections and shifted the power dynamics in President Donald Trump's Washington.

So far, no one has emerged to challenge her. And Pelosi is unmoved.

"I have a broad base of support in the country, financially, politically, and otherwise, which is valuable to our caucus," argued Pelosi.

"None of us is indispensable, but some of us are just better at our jobs than others," she added matter-of-factly.

She toots her own horn to show women how it's done

As she was telling me how qualified she is to be House speaker again, it struck me how unusual it is to hear a woman talk so confidently about how uniquely qualified she is for a job or position she is seeking. Though I am no shrinking violet, it is often hard for me to toot my own horn that way, something I admitted in the moment to Pelosi.

"For most women, frankly, myself included, it is hard to say those words, 'I am uniquely qualified. I deserve this. I earned this. I can do this better than anyone else,'" I told Pelosi.

"You know why I do it? I do it, because I want women to see that you do not get pushed around. You don't run away from the fight," she responded.

Where it all started: Little Italy, Baltimore

I have covered Pelosi for years, and always wondered how she learned to operate and excel in politics the way she does.

For the answer, we went with Pelosi back to where it all started: Little Italy, in Baltimore, Maryland, where she was born to US Rep. Thomas D'Alesandro Jr. and Anunciata D'Alesandro.

When she was six years old, her father became Baltimore's first Catholic mayor.

"He leapfrogged over the Irish. That was a big deal, but it took political organizing to do that," Pelosi explained in an interview at Sabatino's, an Italian restaurant she frequented with her family growing up.

Much has been made of her father's influence on her. Less known is her mother's. Anunciata, who also went by Nancy, was an inventor who patented a device to apply steam to the face -- effectively an at home facial.

But she didn't pursue that passion. She was held back, Pelosi has said, by the times -- and by her father.

Instead, Pelosi's mother helped her father in politics, who was a US representative from Maryland's 3rd Congressional District before he went on to be mayor.

"My mother was very much a part of the organizing. My father was the orator," recalled Pelosi.

Her older brothers said their mother ran what they jokingly called her "moccasin brigade" of other women who would go to political events and get the message out.

"There are two things about what I bring with me from my family in this regard," Pelosi said. "One is to know how to count. That's very important. Count your votes to win the election. Count your votes to win a vote on the floor. The other is listen to your constituents."

But Pelosi says the idea that because she grew up in politics, she always knew that was where she was headed is a myth.

"People are always saying, 'Oh, she knew when she was a little girl she wanted to run for office.' I never thought of that at all, ever, until I did," she insisted.

After college, she wanted to go to law school. Instead, like many in her generation, she got married and started a family.

"When I got married and I had a baby, and then another baby, five in six years," Pelosi recalled.

The Pelosis moved back to husband Paul's hometown of San Francisco. Over the years, she became more and more active in the Democratic Party. But it wasn't until her youngest daughter, Alexandra, was a senior in high school that she ran for an open House seat.

Pelosi tells the story that she went to Alexandra and told her she had a chance to run for Congress. She said her daughter's response was "get a life."

"And I did," Pelosi added.

Pelosi in 'awe' of female lawmakers with young children

Whether she planned it or not, the path that Pelosi took to the House is the one most women used to follow. Women raised their kids, and then they went into politics. "I was sequential," is how Pelosi explains her experience and that of the few women of her generation who actually ran for office.

But that's not the case anymore. Historic numbers of women with young children were already serving in the House and Senate before the election, and that will spike even more once the new 116th Congress is sworn in early next year.

She says she is in awe of the women she serves and works with who are in the throes of parenting.

"I want more young women in Congress who are in the course of raising their children, because it's important for women in that situation to see someone who shares their experience at the table," she said.

"Being a mom, what are you? You're a diplomat, interpersonal relationships. You're a chef. You're a chauffeur. You're a problem solver. You're a nurse. You're a health care provider. You have so much, and that's just with the children, not to mention the other aspects of family," said Pelosi, who notes that motherhood made her much more efficient.

"I don't think that before I had five children in six years that I used time as effectively as I did as a mom. ... I didn't even have time sometimes to wash my face," she laughed, knowing every mother can relate.

The young kids by her side now are her grandchildren. Two of them, Paul and Thomas, were at the podium for her election night victory speech when Democrats learned they'd retaken control of the House.

Not long ago, Democratic men didn't think much of women in leadership

Right now, a historic 102 women are set to be sworn into the House, and that number could rise even more as a handful of outstanding races are decided.

When Pelosi got to the House in 1987, there were only 24 women serving. She says having five older brothers came in handy.

"Growing up in a family of boys helped me, because I was unimpressed," she said.

When she first ran for House leadership 18 years ago, her male Democratic colleagues didn't get it.

"When people came to me and said, 'You should run for leadership,' and I agreed to look at it, then some of the men said, 'Who said she could run?' That was a real motivator."

She also remembers the men being told that "a lot of the women are supporting Nancy to run."

The men responded by saying, "'Well, why? Do the women have a list of things they want us to do? Why don't they just make a list and give us the list?' This is the Democratic Party in the year 2000," Pelosi recalls, a tone of disbelief still in her voice.

How does she wield power differently than a man?

Pelosi says that after meetings, people ask her, "Do you understand how different that meeting would have been if a man were conducting it?"

She says she is told that she listens more carefully than men who conduct meetings.

"You build consensus," Pelosi adds.

She used that female sensibility to gather votes for hard-to-pass legislation many times over the years, but passing the Affordable Care Act, more commonly referred to as Obamacare, is probably the prime example.

It has been widely reported that in January 2010, after Senate Democrats lost their filibuster-proof majority when Republican Scott Brown won a special election, many thought passing the Affordable Care Act, which was not going to get GOP votes, was a lost cause. But Pelosi convinced then-President Barack Obama and others in the White House that it was doable -- and, along with then-Senate Majority Leader Harry Reid, they got it done.

To be sure, the GOP backlash contributed to Democrats losing control of the House in 2010 and Pelosi losing the speakership. But it hasn't been repealed, and she still counts that -- getting Democrats to vote yes despite, for many, the political peril, as one of her biggest legislative accomplishments.

Her advice for women transcends politics

"Have you ever been to a meeting when you're at the table, and a woman makes a suggestion, and then they go to the next person, and then two persons later a man makes the same suggestion, the other gentleman at the table say, 'That's a great idea'"? Pelosi asked me.

"Of course," I replied, because, what woman hasn't had that experience?

"What I have learned later in life, I've concluded, that the reason that they didn't recognize the merit when a woman suggested it is they didn't even listen. They did not even listen to the woman. That's why I say to people, 'Make sure that you have a give-and-take on what you suggest, because some man's going to get the credit for your idea.'"

She says she likely would have stepped down had Democratic presidential nominee Hillary Clinton become president. But when Clinton lost, Pelosi felt compelled to stay on so that there would still be a woman at the table for high-level meetings.

She calls President Donald Trump "respectful of the office that I have," but notes they didn't have many bipartisan meetings to date.

Trump praised Pelosi last week during his post-midterms news conference in the White House.

"I gave her a lot of credit, she works very hard and she's worked long and hard," he said when asked about opportunities for bipartisanship and working across the aisle. "I give her a great deal of credit for how she's worked and what she's accomplished."

With her on track to hold the speaker's gavel again next year, that's likely to change -- and it will be up Pelosi to take her own advice for women.

"You know what the subjects are," she said. "You know how to get it done. Be your authentic self. Be yourself. Know your power."