HOLYOKE — The City Council on Tuesday granted Life Essence a special permit for a marijuana manufacturing facility at 56 Canal St.

Life Essence, a division of Trulieve Cannabis Corp., must now apply for licensing with the Cannabis Control Commission, which oversees the state’s medical and recreational marijuana industry.

The City Council’s Ordinance Committee continued a hearing April 30 on Life Essence’s permit request. The permit garnered no resistance from the committee chaired by Ward 5 Councilor Linda Vacon.

Life Essence proposes renovating a 140,000-square-foot building. The company told the committee it plans to create 200 to 300 jobs.

Ward 3 Councilor David Bartley said Life Essence’s investment was substantial, particularly in job creation. He added that Life Essence and other marijuana-related businesses see opportunities in rehabbing and repurposing Holyoke’s former mill buildings.

The Holyoke Police Department approved the company’s security plan, a requirement under city ordinances. The Holyoke Fire Department signed off on the apparatus turning radius at the site.

The council set forth following conditions for the special permit: Life Essence always pays the commercial property tax rate to the extent allowed by federal, state and local laws; the company hires a minimum 30% Holyoke residents for nonsecurity jobs; and retired police officers from Holyoke or nearby communities will be given hiring preference for security jobs.

The permit prohibits marijuana consumption on the property and deliveries of retail or medical marijuana to residences or individuals.

The business hours must conform to city ordinances. Life Essence plans to operate between 8 a.m. and 8 p.m. The company must seek an ordinance change to extend its hours.

Councilor Rebecca Lisi filed an order that would strike down limited hours for marijuana cultivation and manufacturing businesses. The order noted that past applicants expressed interest in expanding hours of operation. Marijuana plants grown indoors need around-the-clock care. The move also would allow the companies to run three shifts, which requires hiring more personnel.

Lisi’s order must go to the Ordinance Committee for discussion and recommendation.

The council also granted a special permit for Analytics Lab LLC to run a cannabis testing lab at 28C Appleton St., Suite 3. The council set the hours of operation from 8 a.m. to 6 p.m. Monday through Saturday.

The special permit conditions align with Life Essence’s except that Analytics Lab does not allow public access and all waste must be removed by a licensed contractor.

The council granted a special permit in March for EMB Natural Ventures LLC for a 25,000-square-foot marijuana cultivation operation at 140 Middle St., a former factory near the Willimansett Bridge.

In December, the council granted its first-ever special permit to Solurge for home delivery of medical marijuana. The state allows home delivery of medical marijuana under strict security and exacting conditions.