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Larry King is moving on ... once again -- he's divorcing his 7th wife, Shawn Southwick King.

Larry filed divorce docs Tuesday in L.A. Superior Court ... pulling the plug on his 22-year marriage to Shawn. The couple does not have any minor children -- their 2 sons, Cannon and Chance ... are 19 and 20 years old, respectively.

They've been down this road at least once before. In 2010, the former CNN host filed for divorce, and it was actually a race to the courthouse -- Shawn tried to file first, but Larry's legal team was faster on the draw. Didn't matter in the end ... he and Shawn eventually reconciled.

They dealt with more marital turmoil in 2016, when they publicly addressed cheating rumors.

Play video content 2/27/19 TMZ.com

The breakup comes on the heels of Larry's medical crisis in April, where he suffered what doctors described to Shawn as a heart attack.

This will be 85-year-old Larry's 8th divorce ... assuming he goes through with it this time. He married one of his wives, Alene Akins, twice ... that was way back in the 1960s.

Lord, he was born a ramblin' man ...