A Brisbane businessman charged with murdering his wife has agreed to provide police with a sample of his DNA.

Gerard Baden-Clay has made two brief appearances before the Brisbane Magistrates Court today.

Allison Baden-Clay, 43, disappeared from her Brookfield home in Brisbane's west in April.

Her husband reported his wife missing the next day - saying she never returned from a late night walk.

The mother of three's disappearance sparked an extensive search involving hundreds of State Emergency Services volunteers and police.

After a 10-day search, her body was discovered by a canoeist on the muddy banks of Kholo Creek at Anstead, 10 kilometres from the Baden-Clay family home at Brookfield.

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Last night Gerard Baden-Clay, 41, was charged with her murder after being formally interviewed for several hours at the Indooroopilly police station.

He has also been charged with interfering with a corpse.

His first appearance before the Brisbane Magistrates Court today lasted just a minute as he was remanded in custody to appear again on July 9.

He sat with his back to the public gallery.

He was brought back before the court about an hour later when prosecutors sought and were granted a forensic order to take a DNA sample.

The order is for a sample of Gerard Baden-Clay's beard.

His lawyers say their client maintains his innocence and will vigorously defend the murder charge.

His legal team has made an urgent application to the Supreme Court for their client's release on bail.

The application will be heard next week.

Premier Campbell Newman says the matter now needs to go through the court process.

"What a terrible, traumatic time this is for the family, the friends and particularly the children," Mr Newman said.

"I'm sure everybody in Queensland is just very, very sympathetic to everything that they're all going through."

Mrs Baden-Clay's family has released a statement thanking those involved in the investigation of her death.

"On behalf of Allison’s loving family and friends, we would like to thank all the people who have worked so tirelessly in the wake of this terrible tragedy," the statement says.

"We are extremely grateful for the support of the community, the people of Brookfield, the SES and the police who have gone beyond the call of duty to find answers and help restore peace to our lives.

"We love Allison and will always miss her dearly.

"We have a long road ahead of us coming to terms with this horrific crime.

"We would ask everyone to respect our privacy during this very difficult time. The family will be making no further comments on the matter at this stage."