Washington state health officials said the man, a resident of Snohomish County, Wash., returned Wednesday from a trip to the region where he was visiting relatives in Wuhan, where the outbreak began. Shortly after arriving at Seattle’s international airport, he began feeling ill and reached out to his health-care provider on Sunday. Local, state and federal officials quickly collected samples and sent them to the Centers for Disease Control and Prevention for testing. His case was confirmed Monday as the coronavirus that has sickened close to 300 people in China and others in Thailand, Japan, Taiwan and South Korea.

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CDC officials said Tuesday that they are expanding screening to international airports in Atlanta and Chicago. More than 1,200 travelers have already been screened since Friday, with no one yet referred to a hospital or discovered to be ill with the virus. Federal officials will also direct travelers arriving in the United States on direct and indirect flights from Wuhan to those five airports for screening. That process is getting worked out in the coming days. For example, if a passenger was originally scheduled to fly from Wuhan to Shanghai and then Boston, that flight would most likely be rerouted to JFK for screening, and then Boston, CDC officials said. Screenings are being conducted in English and Mandarin.

The Washington state man’s case originated several days before airport screening began, but local, state and federal officials said they were on alert and quickly collaborated to test him and put precautions in place. A small number of health-care workers and patients who may have been exposed to him have been told to watch for symptoms and are being monitored, Washington state health officials said. Officials are tracing the people he may have come into contact with in both China and the United States.

Officials praised the man for taking the initiative to reach out to his health-care provider. “He was a very astute gentleman,” said Scott Lindquist, Washington state’s epidemiologist. “He was looking at the Internet actively” and saw information about the virus and its spread, Lindquist said in a news briefing on Tuesday.

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Nancy Messonnier, director of the CDC’s National Center for Immunization and Respiratory Disease, said the risk posed by the virus to the general American population is low but that older adults with underlying health conditions may be at increased risk. She said federal officials are prepared to respond quickly.

“This is an evolving situation and, again, we do expect additional cases in the United States and globally,” she said.

The CDC and officials from homeland security and transportation agencies are working out how future travelers arriving in the United States from Wuhan will be redirected to the five airports. U.S. officials want to make sure every time someone books a flight from Wuhan to the United States, their first point of entry is one of those airports, said Martin Cetron, director of the CDC’s division of global migration and quarantine. Only JFK and San Francisco airports have direct flights.

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The process is complex and will involve “reissuing tickets and redirecting passengers all over the globe,” Cetron said.

In addition to the expanding airport screening, the CDC has raised its travel alert notice from a level 1 to a level 2, urging travelers to Wuhan to avoid contact with sick people, animals (alive or dead) and animal markets.

The outbreak has grown rapidly in recent days, with authorities in China reporting confirmed cases in multiple cities as hundreds of millions of people in China and elsewhere in Asia are on the move in the run-up to the Lunar New Year, the biggest travel event in the world. The infection is believed to have begun among people who shopped or worked at an animal market in Wuhan. But its rapid spread led officials to conclude that people, as well as animals, could transmit the infection.

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The Washington state man did not visit that market and did not know anyone who was ill, Washington state officials said.

The source of the man’s infection raises more questions and concerns about human-to-human transmission of the disease. Chinese officials have confirmed that phenomenon is taking place.

To control this outbreak, health officials are trying to determine whether new cases being reported in other cities in China and elsewhere can be traced back to Wuhan, said Tom Inglesby, director of the Center for Health Security at the Johns Hopkins Bloomberg School of Public Health. If the disease has been circulating independently in other parts of the country, that information would affect not only how China contains it, but also how other public health agencies in the world seek to prevent its spread, he said.

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Coronaviruses are a large family of viruses ranging from the common cold to much more serious diseases and can infect both humans and animals, according to the World Health Organization. The strain spreading in China is related to two other coronaviruses that have caused major outbreaks in recent years: Middle East respiratory syndrome, also known as MERS, and severe acute respiratory syndrome, or SARS.

“Since this is a respiratory virus, it is spread easier than Ebola, so it brings with it more fear of easily being transmitted between people,” said Matthew Frieman, a virologist and associated professor at the University of Maryland School of Medicine who studies coronaviruses.

The WHO is meeting Wednesday to decide whether to declare the outbreak a public health emergency.

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