An eastern suburbs radiologist accused of stalking a former lover, his sisters, his new girlfriend and her parents left them so badly traumatised that some contemplated suicide, a Sydney court has heard.

Dr Denise Lee, 39, met Mathew Holberton on Tinder in 2015, starting what the prosecution characterised as a "very brief relationship".

Radiologist Denise Lee appears at Downing Centre court accused of stalking a former Tinder date. Credit:Nick Moir

After it ended, Mr Holberton moved to Melbourne where he "resumed his life", said Senior Sergeant Amin Assad on the first day of what is expected to be a 10-day trial at the Downing Centre on Monday.

Dr Lee is facing six counts of using a carriage service to menace/harass, two counts of contravening an apprehended violence order and two counts of stalking.