Vandals have trashed an Islamic community centre in Canberra's south, causing hundreds-of-thousands of dollars damage.

It is the second time the Canberra Islamic Centre at Monash has been vandalised in a fortnight.

Centre president Azra Khan says the facility was trashed some time on Sunday.

"They haven't left anything intact," she said.

"There's holes in the walls. The lights have been demolished, the main power board has been demolished. They knew exactly what they were doing, we can't operate any of the lights.

"Paintings have been ripped off the walls, artworks donated to the centre have been damaged."

There is graffiti on the external walls and the library has also been upturned.

Five televisions that had been replaced after the first attack were also destroyed.

Mrs Khan says the centre will have to consider further security measures.

"I think it's because it's an Islamic centre," she said.

"Clearly they don't like us. Clearly there's a bunch of people who have been targeting the centre. I think it's the same people."

She says it is an unfortunate incident.

"Canberra is an extremely safe and tolerant community and the people here are welcoming and understanding," she said.

"Clearly we need more awareness raising and far more community support. More people need to come out and say this is not something we as a community want to tolerate."

Police are investigating the incident and say the attacks at the centre appear to be linked.

Tuggeranong Police Station Sergeant Joanne Cameron is urging anyone with information to come forward.

"I put forward that the people that have done this have no sense of self about what they're doing to disrupt a valuable community resource," she said.

"Lines of inquiry about those motivations about why this crime was committed sit fairly and squarely with the people who committed this crime."

Sergeant Cameron says the attacks are disgusting.

"It's a community organisation that's trying to do good things for the community," she said.

"We should all be disgusted with the damage that's been done."