The Garden’s college basketball season starts with a bang and finishes in similar fashion.

The eyes of the sport will be zeroed in on MSG on the first night of the season, when Kansas meets Duke and Kentucky takes on Michigan State in the annual Champions Classic on Nov. 5. And on the second-to-last weekend of the year, the arena will again be the focal point, as it plays host to the NCAA Tournament’s East Regional between March 27-29 for the third time since 2014.

Those two events highlight a blockbuster season of college basketball at the Garden, which released the completed schedule to The Post on Thursday. It includes the two-night 2K Classic on Nov. 21-22 featuring Duke and Georgetown, the Jimmy V Classic (Louisville vs. Texas Tech and UConn vs. Indiana) on Dec. 10, seven St. John’s regular season games and the Big East Tournament from March 11-14.

The Holiday Festival is back on Dec. 7, when St. John’s hosts West Virginia in the first year of the Big East-Big 12 Challenge, and so is the Big Ten Super Saturday, as Michigan and Rutgers meet in wrestling and basketball on Feb. 1. The year wraps up with the NIT on March 31 and April 2.