European soccer’s top clubs are due to hold a secret meeting with UEFA on Tuesday to discuss potentially radical changes to the format of the Champions League, the most prestigious tournament in the game, according to several people familiar with the matter.

After years of speculation, these will be the first formal talks between the bodies with the explicit intention of reshaping European soccer. The talks are just beginning, and any changes are far from certain and unlikely to take effect before 2024.

But the changes that will be discussed this week in Nyon, Switzerland, could be dramatic in scope. On the table is a nascent proposal that could replace the qualifying structure of the tournament with a more closed system of promotion and relegation that would favor Europe’s biggest and richest clubs and make it harder for smaller teams to qualify.

Another proposal would move Champions League games from their midweek slots into the weekend—a change that would subvert the primacy of each country’s national league, including the English Premier League.

The clubs will be represented at the talks by the board of the European Club Association, a trade body led by Andrea Agnelli, the Fiat scion and chairman of Juventus, representing 232 European teams. The board also includes executives from European giants such as Manchester United, FC Barcelona, and Bayern Munich. The group has been pushing for years to revamp European competitions to protect the larger teams and guarantee their participation.