AUSTIN, Tex. (AP) — At least seven more scientists have resigned in protest from Texas’ embattled $3 billion cancer-fighting program, claiming that the agency in charge of it is charting a “politically driven” path that puts commercial interests before science.

The Cancer Prevention and Research Institute of Texas, created with the backing of Gov. Rick Perry and the cyclist Lance Armstrong, a cancer survivor, has awarded nearly $700 million in grants since 2009; only the National Institutes of Health offers a bigger pot of cancer-research money.

Scrutiny of how the state agency selects projects has intensified since May, when its chief scientific officer, Dr. Alfred G. Gilman, a Nobel laureate, resigned in protest after it approved a $20 million commercialization project without scientific review.

Phillip A. Sharp, another Nobel laureate, was among seven scientists who resigned last week, writing in his resignation letter that the agency’s decisions have carried a “suspicion of favoritism” in how the state is handing out taxpayer dollars.