CLEVELAND — The Chicago Cubs, who have endured 108 years without a championship, and the Cleveland Indians, who have waited a mere 68, are nothing if not patient.

So what’s one more day?

All those decades of disappointment and heartbreak will be washed away for one of these franchises on Wednesday night as the 112th World Series culminates in a Game 7. The Cubs ensured there would be a winner-take-all game by routing the Indians on Tuesday night, riding a grand slam and six R.B.I. by Addison Russell to a 9-3 victory.

The Cubs will send Kyle Hendricks to the mound as they try to become the first team to rally from a three-games-to-one deficit since Kansas City beat St. Louis in 1985, and the first to do so on the road since Pittsburgh won at Baltimore in 1979.

But they will have to beat the Indians’ ace, Corey Kluber, who has dominated them twice in this Series, allowing just one run in 12 innings while striking out 15.