A woman was killed in a collision in St. James Town on Friday morning that involved a TTC bus, according to Toronto police.

"Numerous" callers reported the incident to police around 6:30 a.m., said Sgt. Brett Moore. Officers arrived to the scene at the corner of Bloor Street E. and Sherbourne Street to find "a woman in the middle of the intersection."

The woman was taken to a trauma centre, where she was pronounced dead. She was in her 60s, Moore said, but police are still working to identify her.

Moore confirmed that a TTC bus struck the woman, but it's not yet clear exactly what happened or if there may have been another vehicle involved as well.

"We're working with the TTC … but we do know the bus is equipped with camera equipment that we'll be looking to get access to," he told CBC Toronto.

Officers with Toronto police's traffic services unit are investigating the fatal collision. They are appealing for any witnesses to come forward, and for any local businesses that may have captured the collision on video to turn it over to police.

The busy intersection is currently closed off to all road and foot traffic.

"The roads are going to be closed, definitely, for a couple of hours. We only get one chance to collect evidence from the scene," Moore said.