Football star Michael Sam and his college sweetheart may have called it quits just six months after getting engaged.

Sam and Vito Cammisano met as students at the University of Missouri and began dating in 2011, with Sam proposing to Cammisano atop St. Peters Basilica in Vatican City this past January.

The two have not been seen together in months however, and now Sam has deleted all photos of Cammisano from his Instagram account - including their engagement photo.

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Done: Michael Sam and boyfriend Vito Cammisano have reportedly ended their relationship just six months after getting engaged in Vatican City (above)

Sign: Cammisano filmed a YouTube video last week in which he is not wearing his engagement ring (above)

New job: Sam signed a two-year contract with the Alouettes in the Canadian Football League last month (above) after realizing no NFL teams would be inviting him to training camp

TMZ first pointed out that Sam, 25, had deleted his Instagram photos, while also noting the fact that he recently had to leave training with the Montreal Alouettes for a personal reason, but there were no signs on concern from Cammisano.

Furthermore, Cammisano, 24, just filmed a YouTube video in his quest to become a video blogger and is not wearing his wedding ring on camera.

Perhaps the biggest indication however is that the hugely public couple, who were happy to walk red carpets earlier in the year while publicly displaying their affection towards one another, were shockingly tight-lipped when last week's gay marriage ruling came down from the Supreme Court.

Reps for the two men did not respond to requests for comment.

PDA: The couple has always been very public about their relationship, but have been tight-lipped about the state of their engagement

There are also signs that the men may still be fine as well, as Sam still has all of his photos with Cammisano up on his Facebook page, and in Cammisano's YouTube video, Sam's Arthur Ashe Courage Award which he received at last year's ESPYs is seen sitting on a counter in the background.

Cammiosano is also still using a photo of himself with Sam as his Twitter avatar.

The last photo of the two together was taken in early May and posted on Cammisano's Instagram page.