Italy is to close all schools and universities from Thursday to try to contain its worsening coronavirus outbreak, a government source said, as cases continued to rise in Europe's worst-hit country.

Only schools and universities in the northern regions most heavily affected by the epidemic have been closed so far.

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Italy's death toll due to the new coronavirus had reached 79 on Tuesday, with more than 2,500 confirmed cases since the outbreak began 13 days ago.

The extension of the schools shut-down will last at least until mid-March, the source said.

In another sign of mounting concern, the sports minister said on Wednesday the government was likely to order all top-flight Serie A football matches be played behind closed doors until the outbreak eases.

So far, games had been cancelled in the northern regions but had gone ahead over the rest of the country.

The virus outbreak remains centred on the wealthy and populous region of Lombardy around Milan and the neighbouring regions of Veneto and Emilia Romagna, but cases are spreading around the whole of the Italian peninsular.

On Wednesday, Rome's Spallanzani infections diseases hospital said it had 20 coronavirus patients, while others were being treated at home in and around Italy's capital and largest city.

The southern island of Sicily has reported 18 cases. The daily nationwide update will be provided by the Civil Protection Agency at around 17:00 GMT.

The San Paolo stadium in Naples was sanitised before the second leg of the Coppa Italia semifinal between Napoli and Inter Milan, a game which has since been postponed as part of measures to contain the coronavirus outbreak [Ciro De Luca/Reuters]

Emilia Romagna's regional government said on Wednesday two of its members had tested positive.

The outbreak has heavily disrupted daily life in the north, with cinemas, museums and other public venues closed and many events cancelled including fashion shows and trade fairs.

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The National Health Institute has instructed Italians to wash their hands frequently, remain at least a metre apart (about one yard), refrain from hugging each other and avoid crowded places.

On Wednesday, the government issued a directive instructing public sector managers to reorganise offices to enable staff to work from home.

Italy's chronically weak economic growth looks sure to suffer, with the tourism sector taking a huge hit from a wave of cancellations by holidaymakers.

Industry lobby Confindustria said the country was in recession, forecasting a fall in gross domestic product in both the first and second quarters of this year.

Confturismo, the tourist industry's confederation, said on Wednesday the sector was 'on its knees'.

It forecast a drop of some 32 million Italian and foreign tourists in March-to-May, with a loss to the industry of some 7.4 billion euros ($8.2bn).