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Actress Felicity Huffman will plead guilty over her role in the nationwide college-admissions scandal — along with a dozen other wealthy parents, federal prosecutors announced Monday.

The “Desperate Housewives” star will join 12 other disgraced moms and dads in copping to conspiracy to commit mail fraud and honest services mail fraud for paying bribes to ease their privileged progenies’ admission into top schools — by either fudging the kids’ exam scores or getting coaches to name them as bogus athletic recruits.

They all face up to 20 years behind bars.

In a statement following the announcement, Huffman, who is married to “Shameless” star William H. Macy, said she has “deep regret” for what she’s done and accepts “full responsibility” for her actions and their consequences — but claimed her eldest daughter, Sophia Grace Macy, was not complicit.

“I am ashamed of the pain I have caused my daughter, my family, my friends, my colleagues and the educational community,” Huffman said. “I want to apologize to them and, especially, I want to apologize to the students who work hard every day to get into college, and to their parents who make tremendous sacrifices to support their children and do so honestly.

“My daughter knew absolutely nothing about my actions, and in my misguided and profoundly wrong way, I have betrayed her. This transgression toward her and the public I will carry for the rest of my life. My desire to help my daughter is no excuse to break the law or engage in dishonesty.”

Fellow actress Lori Loughlin, of “Full House” and its reboot, “Fuller House” — who along with her husband, clothing designer Mossimo Giannulli, was also arrested in the scam — has not yet signaled an intent to plead guilty.

But among the other well-heeled parents who are copping to the charges are New Yorkers Greg and Marcia Abbott — whose rapper-wannabe son infamously defended his parents’ actions outside their tony Fifth Avenue apartment while puffing away on a cigar filled with pot.

Mea culpas are also coming from marketing CEO Jane Buckingham, Connecticut attorney Gordon Caplan, real-estate developer Robert Flaxman and wine maker Agustin Huneeus.

Former University of Texas tennis coach Michael Center — who the feds say received a $60,000 cash payoff in an Austin parking lot to get a kid into his school — will also plead guilty to the same charges, prosecutors say.

They were among dozens of people busted across the country last month for participating in the scheme organized by William “Rick” Singer.

The California college-prep adviser — who pleaded guilty to conspiracy to commit money laundering, conspiracy to defraud the United States and obstruction of justice, and worked with the feds to bring down his clients — took in more than $25 million to secure the parents’ elite offspring places at schools including Yale, Stanford and Northwestern, prosecutors say.

In the case of Huffman, prosecutors say she paid Singer at least $15,000 so he could arrange for crooked test proctor Mark Riddell to change the answers on Sophia Grace’s SAT exam.

“Ruh ro! Looks like [my daughter’s high school] wants to provide own proctor,” Huffman wrote to Singer at one point, according to court documents.

But they eventually got the teen’s test moved from the school to a test center in West Hollywood — where Riddell pretended to proctor the exam, but really corrected the girl’s answers after she’d left.

She scored a 1420 — an improvement of around 400 from the PSAT exam she’d taken on her own a year earlier.

Court documents allege Huffman’s husband, Macy, also met with Singer to discuss repeating the stunt with younger daughter Georgia Grace Macy — but ultimately didn’t follow through with it.

Macy was not charged in the scandal.

Gregory Abbott — the founder of food- and drink-distribution company International Dispensing Corp. — and his wife are accused of paying more than $100,000 to Singer for Riddell to correct the answers on their daughter’s ACT and SAT subject tests.

The daughter received a perfect 800 on the doctored math test and 710 out of 800 on the literature subject test, while Singer told her dad she scored in the “mid-600s” on her own, according to court documents.

After the Abbotts’ arrest, son Malcolm — who never went to college — spoke to The Post outside the family’s Upper East Side home, where he smoked pot while declaring, “everyone has a right to go to college, man.”

Malcolm — who raps under the name “ Billa” — also took the opportunity to plug his latest album, which a Post reviewer later labelled as “white-privilege rap.”

While most of the parents taking pleas opted for Singer’s exam-cheating services, some opted to have him grease their kids’ entrance into college by bribing athletics coaches — or for both.

Huneeus coughed up more than $300,000 to get his daughter into the University of Southern California via both methods, according to court documents.

First, he paid Riddell to juice up her SAT exam, gaining her a 1380 out of 1600 — any higher would have aroused suspicion due to the girl’s grades, Singer told the dad.

Then, Singer bribed the college’s senior women’s associate athletic director, Donna Heinel, to get the girl named as a water-polo recruit — even though Huneeus admitted himself that she was “not worthy to be on that team,” according to court documents.

In September 2018, Singer gave the school the inflated SAT score alongside a fake athletic profile claiming she was a “3-year Varsity Letter” winner in water polo and a photo of some other girl playing — and Heinel sent them a conditional acceptance letter two months later.

Riddell — a Harvard grad who apparently aced Singer’s client’s tests with his own smarts — also plans on pleading guilty to conspiracy to commit mail fraud and a count of conspiracy to commit money laundering, according to court documents filed in Boston federal court.

According to the agreement, prosecutors are recommending prison time and a fine at the “low end” of guidelines. Riddell will also have to forfeit the almost $240,000 he earned from Singer’s scheme.

Heinel, who has since been fired from USC, has entered a not guilty plea to racketeering conspiracy.

The school’s water polo coach, Jovan Vavic, was also fired and has also pleaded not guilty to the same charges.

With Wires