The Senate passed a historic $2 trillion coronavirus relief package Wednesday night, as it tries to stem the destruction the pandemic has brought to American lives and wallets.

The chamber approved the mammoth bill — the largest economic rescue package in U.S. history — in a unanimous 96-0 vote after days of furious negotiations, partisan sniping and raised tempers on the Senate floor. The bill now heads to the House, which will push to pass it by voice vote Friday morning because most representatives are out of Washington.

"This is a proud moment for the United States Senate and for the country and we're going to win this battle in the very near future," Senate Majority Leader Mitch McConnell, R-Ky., told reporters after the vote.

The 880-page legislation includes one-time direct payments to individuals, stronger unemployment insurance, loans and grants to businesses and more health-care resources for hospitals, states and municipalities. It includes requirements that insurance providers cover preventive services for COVID-19.

Read more: Here's what's in the $2 trillion coronavirus stimulus bill

House Speaker Nancy Pelosi expects her chamber will approve the measure in a "strong, bipartisan vote" on Friday, she told reporters Thursday.

The Senate rushed to pass the sweeping aid bill as data are expected to show a historic spike in unemployment claims after businesses across the country shuttered in an attempt to slow the outbreak's spread. Some hospitals have started to buckle under a flood of patients, asking for critical supplies such as masks and ventilators.

As of Thursday morning, U.S. coronavirus cases numbered more than 69,000, while deaths have now topped 1,000, according to Johns Hopkins University.

The chamber approved the plan to combat the outbreak as the crisis started to thin its ranks. Sen. Rand Paul, R-Ky., did not vote after testing positive for COVID-19, and neither did GOP Sens. Mitt Romney and Mike Lee of Utah, both in isolation after contact with their colleague. Sen. John Thune of South Dakota, the second-ranking Republican, also missed the vote after feeling ill.

While the Senate took precautions Wednesday such as keeping votes open longer to reduce crowding, senators still huddled in groups and chatted.