TORONTO (AP) - Tom Clarke has been dealing marijuana illegally in Canada for 30 years. He wrote in his high school yearbook that his dream was to open a cafe in Amsterdam, the Dutch city where people have legally smoked weed in coffee shops since the 1970s.

Turns out, Clarke didn't have to go nearly so far to open his own retail cannabis outlet.

On Wednesday, Canada becomes the second and largest country with a legal national marijuana marketplace. Uruguay was first. Clarke, 43, will be among the first to legally sell recreational marijuana when his shop opens at midnight in Newfoundland, Canada's easternmost province.

"I am living my dream. Teenage Tom Clarke is loving what I am doing with my life right now," he said.

At least 111 legal pot shops are planning to open across the nation of 37 million people on the first day, according to an Associated Press survey of the provinces. That is a small slice of what ultimately will be a much larger marketplace.

No stores will open in Ontario, which includes Toronto. The most populous province is working on its regulations and doesn't expect stores until next spring.

FILE - In this Oct. 4, 2018, file photo, Thomas Clarke poses for a photo outside his cannabis store, THC Distribution, in Portugal Cove-St. Philip's, Newfoundland and Labrador. On Wednesday, Oct. 17, Canada becomes the second and largest country with a legal national marijuana marketplace. Clarke will be among the first to legally sell so-called recreational marijuana when his shop opens at midnight. (Paul Daly/The Canadian Press via AP, File)

Canadians everywhere will be able to order marijuana products through websites run by provinces or private retailers and have it delivered to their homes by mail.

Canada has had legal medical marijuana since 2001, and amid excitement over the arrival of legal recreational pot, many in the industry spent the last days of prohibition on tasks familiar to any retail business - completing displays, holding mock openings and training employees to use sales-tracking software.

"It's been hectic," said Roseanne Dampier, who joined her husband - both former welders - in opening Alternative Greens, a licensed store in Edmonton, Alberta. "We have been extremely busy just trying to be able to meet that deadline."

Canada's federal government, led by Prime Minister Justin Trudeau, spent about two years planning for legalization, fueled by a desire to bring dealers like Clarke out of the black market and into a regulated system.

Canada's national approach has allowed for unfettered industry banking, inter-province shipments of cannabis and billions of dollars in investment - a sharp contrast with national prohibition in the United States. Nine U.S. states have legalized recreational use of pot, and more than 30 have approved medical marijuana.

"Now that our neighbor to the north is opening its legal cannabis market, the longer we delay, the longer we miss out on potentially significant economic opportunities for Oregon and other states across the country," Democratic Sen. Ron Wyden of Oregon said in a statement.

U.S. Customs and Border Protection invited Canadian media to a conference call on Tuesday so officials could reiterate that marijuana remains illegal under U.S. federal law and that those who are caught at the border with pot are subject to arrest and prosecution.

A patchwork of regulations has spread in Canada as each province takes its own approach within the framework set out by the federal government. Some are operating government-run stores, some are allowing private retailers, some both.

Alberta and Quebec have set the minimum age for purchase at 18, while others have made it 19.

The provinces also have been able to decide for themselves how much to mark up the marijuana beyond the 10 percent or $1 per gram imposed by the federal government, and whether to allow residents to grow up to four plants at home.

Steve Hawkins, executive director of the Marijuana Policy Project, a Washington-based lobbying organization that has been pressing for legalization since 1995, said it is time for the U.S. to follow Canada's lead.

"Canada is setting a strong example for how to end marijuana prohibition at the national level and replace it with a system of regulated production and sales that is largely governed at the local level," he said. "The U.S. and other countries grappling with the complexities of such a significant policy shift will have an excellent opportunity to learn from the Canadian experience."

As Canada welcomes legalization, supply shortages could develop, as happened in some U.S. states when legalization arrived.

Trevor Fencott, chief executive of Fire and Flower, said his company has 15 Alberta stores staffed and ready to sell marijuana, but the province has supplied only enough product to open three of them Wednesday.

"We're aware of some of the kinks or growing pains that come with creating an industry out of whole cloth in 24 months," Fencott said.

Brenda Tobin and her son Trevor plan to open their pot shop in Labrador City in Newfoundland and Labrador at 4:20 p.m., a reference to 420, slang for the consumption of cannabis. Tobin, a longtime convenience store owner, said they will be cutting a ribbon and cake.

"We are just ecstatic," she said.

She doesn't expect to make much money off the pot itself, noting Newfoundland's 8 percent cap on retail pot profits. She hopes to make money from pipes, bongs and marijuana paraphernalia.

"There's no money in the product itself," she said. "You got to sell $250,000 worth of product in order to make $20,000. That's not even paying someone's salary."

Ontario won't have any stores open until April, after the new conservative government scrapped a plan for state-owned stores in favor of privately run shops. British Columbia on the Pacific Coast will have just one store open on Wednesday, but many more are expected to open in coming months.

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Gene Johnson reported from Seattle. Johnson is a member of AP's marijuana beat team. Follow him at https://twitter.com/GeneAPseattle. Find complete AP marijuana coverage at http://apnews.com/tag/LegalMarijuana

Members of the media attend a preview for one of Quebec's new cannabis stores in Montreal, Tuesday, Oct.1 6, 2018. Canada will become the second and largest country with a legal national marijuana marketplace when sales begin on midnight Wednesday. (Ryan Remiorz/The Canadian Press via AP)

Members of the media attend a preview for one of Quebec's new cannabis stores in Montreal, Tuesday, Oct.1 6, 2018. Canada will become the second and largest country with a legal national marijuana marketplace when sales begin on midnight Wednesday. (Ryan Remiorz/The Canadian Press via AP)