The second week of the N.F.L. season features some teams trying to prove last week was no fluke and others trying to prove their opening-day loss was nothing to worry about. Here is a look at Sunday’s matchups and who we think will win them (all times are Eastern):

Follow our live coverage of N.F.L. Week 2 here.

Seahawks (1-0) at Rams (0-1)

4:05 p.m. on Fox

Line: Seahawks by 3 ½

With the N.F.L. holding its first regular-season game in Los Angeles since Christmas Eve in 1994, the real star of this matchup will be the Los Angeles Memorial Coliseum.

First opened in 1923, the stadium is the longtime home of the University of Southern California, but along the way has hosted two Summer Olympics and two Super Bowls (including the first one); offered refuge for the fleeing Brooklyn Dodgers; and served as a launching pad for Evel Knievel.

The stadium, with a sprawling capacity that can be unforgiving to a team that is not able to attract 80,000 or more fans per week, has been around long enough that this is not even the first time the Rams have relocated the franchise there in hopes of taking advantage of the riches of Los Angeles. In 1946, the Cleveland Rams were struggling, so the ownership forced a move to Los Angeles and then called the Coliseum home until moving to Anaheim in 1980.

No one will confuse the current Rams with any of the hallowed tenants that came before them. Built around a fantastic defensive line, and not much else, the Rams had the No. 1 overall pick in this year’s draft, but have yet to see any returns. Jared Goff, the University of California quarterback they selected, was not active in Week 1 and is not expected to play any time soon after a difficult preseason.