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Jurgen Klopp has indicated that he will make changes to freshen up his Liverpool side for Wednesday night’s Capital One Cup quarter-final tie with Southampton.

It will be the Reds’ fourth game in the space of 11 days and the manager says a gruelling run has taken its toll on some players.

“At this moment I can’t say which team I’ll play because the last game was only two days ago,” Klopp said.

“Yes, I will play the strongest team but that all depends on the situation and how much they played recently.

“You can’t ignore the last game. You can’t ignore the next game. Usually, you need the full squad.

“Really, I have to think about it. It’s a puzzle but in the end it will be our strongest team for sure.”

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Klopp revealed that both captain Jordan Henderson and striker Daniel Sturridge came through their cameos against Swansea City unscathed.

Both were making their first appearance since the German’s appointment but neither will make the starting line up at St Mary’s.

Klopp is also waiting on Philippe Coutinho, who has returned to training having missed the past two matches with a hamstring problem.

“There was no physical reaction from Jordan and Daniel so that’s good news,” he said.

“They did their job and helped us keep the result.

“Daniel did what we had spoken about before. He should be our first target, our first option and that’s what we did. Everyone could see his quality.

“We now have Southampton and we cannot ignore that there could be overtime. I’m sure 120 minutes would be too much for them both.

“We don’t have to think about starting them and knowing that these two players we would have to change for sure.

“But if nothing happens between now and the game they will join us. They are options.

To win titles is a cool thing

“We have to wait with Philippe. We will speak with the medical staff and to Phil. He will be close. It’s possible. We have to double check the situation.”

Victory on the South Coast would book the Reds’ passage to the semi-finals and put Klopp’s men in sight of Wembley.

However, the manager insists the focus is solely on Ronald Koeman’s Saints, who drew 1-1 in the league at Anfield back in October.

“To go to a final would be interesting. To win titles is a cool thing but the quarter-finals is still far away,” he added.

“We don’t have to think about Arsenal, United, City or anything. We have to think about Southampton.

“To get in the half (semi) final we have to beat them and they are strong enough.

“They will want to strike back. They will be hot for this game as they have lost their last two games.

“I have heard that Liverpool and Southampton are not the best of friends so it’s not a friendly!

“If we want to go to half final we have to fight for it.

“Southampton are a good team with a brilliant offensive line. Tadic is difficult to play against.

“They know more about us since the game at Anfield and we know more about them.”