The only starting pitcher to lose a complete-game no-hitter was Ken Johnson of the Houston Colt 45s (pre-Astros), who lost to Cincinnati 1-0 on April 23, 1964. Johnson's throwing error allowed Pete Rose to get to second with one out in the top of the ninth. Chico Ruiz moved Rose to third on a ground ball, and second baseman Nellie Fox's error on a grounder by Vada Pinson let Rose score the game's only run.

Steve Barber (8 2/3 innings) and Stu Miller (1/3 inning) of the Baltimore Orioles lost a no-hitter to Detroit 2-1 on April 30, 1967. The Tigers got both their runs when Barber walked Norm Cash and Ray Oyler to start the top of the ninth. Earl Wilson (who started for Detroit and got the win) bunted them over. After Willie Horton popped up, Barber threw a wild pitch, which let Dick Tracewski (running for Cash) score to make it 1-1. Miller came in to pitch to Don Wert, whose ground ball was booted by shortstop Mark Belanger, allowing Jake Wood (running for Oyler) to score the go-ahead run.

Harvey Haddix pitched 12 no hit innings and lost the game.