Seven feral goats fitted with GPS trackers are rounding up their friends in north-west Victoria, as part of a large-scale pest control program to play out next week.

An estimated 8,000 feral goats are damaging native vegetation in the Murray Sunset National Park, but authorities say the sheer vastness of the half a million hectare park means they are hard to control.

Brendan Rodgers, from Parks Victoria, says a helicopter and a professional shooter will tackle the problem, but "Judas goats" will go in first.

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"They pretty much set up a goat to go and mix with his friends," he said.

"Then his friends are obviously removed, but the Judas goat remains, to mob up again with another group.

"So his friends don't know it, but he's sort of setting them up to be shot."

Mr Rodgers said it was the biggest operation of its size in Victoria, but similar programs had been successful in other states, in particular in eradicating goats on Kangaroo Island in South Australia.

Parks Victoria will close the park after the long weekend in June, and the operation is expected to take about four days and cost approximately $70,000.

A helicopter and a professional shooting company from NSW and Queensland will go out, find the Judas goats using GPS co-ordinates and start shooting the mobs of goats.

Mr Rodgers said current goat control procedures, like trapping, land-based shooting and removal of water sites, had not been making a big enough impact on numbers.

He said there was a standard operating procedure to keep the park safe and also kill the goats as humanely as possible.

The shooters had to target the head or the heart and make sure all animals were deceased before they moved onto the next mob.

"Following some of the work, a vet will go in quickly and examine the carcasses and do an assessment to make sure the shooters are shooting the goat in accordance with the protocols," he said.

Mr Rodgers said the goats shot in this operation would be left in the park to decompose, as they would be mostly in inaccessible areas.

But a lot of farmers do trap goats on the outskirts of the park and sell them for meat.

Mr Rodgers said Parks Victoria would follow up with another survey in about a year, and monitor vegetation sites to see if the shoot had been successful.

"We don't have a particular target. With pest animals it's not about targets, it's just about reducing as many as you possibly can, whether it's rabbits, goats or foxes."

Visitors are encouraged to check the Parks Vic website for details of the closure.