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JERUSALEM, Israel - More than 200 Orthodox Jews protested on Monday against the pope's planned visit to the site where Christians believe Jesus Christ had his Last Supper.

The Cenacle, a building on top of Mount Zion outside Jerusalem's walls, has resonance with all the Abrahamic religions. For Jews, it is the Tomb of King David and it is also the site of a 16th-century mosque.

But Orthodox Jews say that letting Christians pray there is in direct conflict with their religious teachings.

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Protesters gathered outside the tomb on Monday, with loudspeakers broadcasting prayers and calls for more people to join their cause.

"Under Jewish law it is a big problem...basically they are taking over the place," organizer Rabbi Avraham Goldstein told NBC News.

Two Ultra Orthodox Jews on Sunday walk past a large poster of Pope Francis on the Christian Information Center in the Old City of Jerusalem. THOMAS COEX / AFP - Getty Images

This controversy comes on the heels of a string of vandalism attacks allegedly perpetrated by far-right Jewish groups on Christian sites in the holy city.

Several Christian churches have been defaced and the top Roman Catholic cleric in the Holy Land said the spate "poisons the atmosphere of coexistence."

Fourteen attacks by suspected far-right Israelis have been reported in the past year, according to Reuters.

Several have been carried out over the last month, including a death threat daubed in Hebrew at the Assembly of Bishops at the Notre Dame Center in East Jerusalem, where the pontiff is due to meet Israeli Prime Minister Benjamin Netanyahu.

- Dave Copeland, Paul Goldman, Lawahez Jabari and Alexander Smith