BEIRUT (Reuters) - An air strike by the U.S.-led coalition against Islamic State has killed 25 people including children in the militant group’s last enclave on the Euphrates in Syria, a war monitor said on Monday.

The air strike took place in the settlement of Dahra Alouni close to al-Shaafa region, and more than half of those killed were women and children, said the Britain-based Syrian Observatory for Human Rights.

Asked about the report, the coalition spokesman, Colonel Ryan Dillon said: “We take all allegations seriously and as we always do we will put it into our civilian casualty assessment and we will publish the results of those on a monthly basis.”

Islamic State has lost most of the territory it had captured in Syria in the face of military campaigns by both the U.S.-led coalition that supports an alliance of Syrian militias and by Syrian government forces, which are backed by Russia and Iran.

But the jihadist group still holds small pockets of land in eastern Syria on both sides of the Euphrates, and also in a southern suburb of Damascus and in the country’s southwest.

War monitors say coalition air strikes during the campaigns against Islamic State in Syria and Iraq have killed large numbers of civilians. The coalition says it takes great care to avoid civilian casualties.