Melbourne mother of twins Annie Nolan claims she has received death threats after a photo she posted online of her daughters with sarcastic signs on their laps went viral.

Ms Nolan said she posted the photo on her 'Uncanny Annie' Facebook page earlier this week for a laugh between her friends, who are also mothers of twins.

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On the signs, she answers a series of questions she said she is asked every day: "Yes, they are mine. Yes, they are twins. Yes, both girls. No, not identical. Yes, I know they look alike though. Yes, I'm sure they aren't identical," one sign reads.

"Conceived by f---ing. Born via c-section. You have twins in your family? *Great*. They don't run in my family...until now. Yes, my hands are full (sometimes with two glasses of wine just to get through). Yes, triplets would be harder," the second sign reads.

The photo went viral overnight, making international headlines and an invitation from Time magazine followed for Ms Nolan to write about what she learned from sharing the photo.

On 774 ABC Melbourne Mornings, she said she has been shocked by the reaction online.

"There's the typical trolls who send death threats," she said.

"I've had a couple inbox messages - one saying if they saw me on the street they'd love to glass me in the face."

She said she has not taken the "scary ones" seriously, but some responses from bereaved mothers and women attempting IVF have been more troubling.

"Mothers saying I was ungrateful ... that was never my intention," she said.

"One particular person kept sending me photos of her child who had passed away and that was the one that had affected me, so I had to take some time off the internet."

The photo, she said, was intended to make light of how often she is asked the predictable, and sometimes invasive, questions.

"It's almost like walking around with a unicorn when you've got twins," she said.

"People assume they're IVF and every time I get asked the question I just cringe thinking how that must make (IVF mothers) feel.

"It's kind of like looking in someone's trolley and asking why they've got some maxi tampons in there - you don't need to bring it up.

"You can question 'why' in your head but it's very personal."

The online exposure has given her a few thousand extra followers on her blog, and, for the first time in their relationship, Ms Nolan has had more media attention than her partner - Western Bulldogs player Liam Picken.

When asked what was next in store, Ms Nolan said she had no grand plans for her international fame.

"I'm just going to plod along doing what I was already doing," she said.