WASHINGTON — Following the playbook of their crusade against the Affordable Care Act, congressional Republicans on Friday showed no sign of letting up in their effort to pressure the White House over the Iran nuclear accord, even after the Senate effectively settled the matter and blocked a Republican resolution aimed at stopping the deal.

The House, as expected, rejected the Iran deal overwhelmingly, a vote that was sharply along partisan lines.

Some House Republicans also said they were contemplating a lawsuit that would claim that the White House failed to disclose the full details of the nuclear accord as required by a law adopted last spring. And the Senate has scheduled a repeat vote on Tuesday, trying to bait any wavering Democrats to switch their position.

Senate Democratic leaders said they were confident their ranks would hold. But there was some exasperation as they recognized that they would be in for a protracted battle, at least through the 2016 presidential and congressional elections and possibly beyond.