Two people have been arrested in connection with the disappearance of a Worcester teenager who has been missing since March 14.

James Howze, 19, of 37 Harvard Ave, Providence, and Lara Corey, 22, of 27 Boston Turnpike Road, Westboro, were arrested in Colonie, N.Y., last night on fugitive from justice charges, according to a spokesman for Worcester District Attorney Joseph D. Early Jr.



The alleged victim, Joseph P. Webster, 19, of Brattle St., Worcester, had not been found as of tonight and family members are very concerned. Mr. Webster is mildly autistic and is also diabetic, requiring daily insulin injections.



Mr. Webster was seen at the Motel 6 in Northboro some time after his family reported him missing to Worcester police March 14, which was around the same time that Ms. Corey was staying at the motel.



The district attorney said Mr. Howze is facing charges of assault and battery with a dangerous weapon, a knife, and larceny of a motor vehicle. Ms. Corey has been charged with larceny of a motor vehicle. Warrants for both had been issued as a result of the investigation and the district attorney is working to have the two returned to Massachusetts to be arraigned in Westboro District Court. It is unclear when that may happen.



Mr. Webster’s uncle, Gerardo Sarli, who runs Gerardo’s Bakery on West Boylston Street, said the family is worried because his nephew did not have enough insulin with him to have survived from the time he was missing until now. He said the teenager is fastidious about his health care and he, “never spent a night away from home.



“He’s a very kind kid,” Mr. Sarli said. “He’s had a girlfriend for two years and she is just devastated.”



He said some members of their large Italian family — Mr. Webster is one of 17 grandchildren on his mother’s side — had been hanging missing person posters at stores near Motel 6.



Mr. Webster’s mother, Amalia Webster, said she is distraught over the disappearance of her youngest child, who has the maturity of a 14- or 15-year-old because of his autism. She said he was diagnosed with diabetes at age 9 and is very careful about monitoring his condition and staying healthy.



“I just want to have him brought home,” she said.



During the investigation, state police detectives from the Worcester district attorney’s office focused on the Motel 6 on Route 9 in Northboro. On Tuesday, they gathered evidence in and around the motel and concentrated on Room 214 where, an employee said, large chunks of carpeting were removed.



They also scoured the back of the motel where side doors often used by guests lead into the rear parking lot, where there are no security cameras. There are a few small, ramshackle sheds behind the motel and debris is strewn about at the wood line.



Police were also looking for Mr. Webster’s silver 2003 Cadillac Seville, which was reportedly seen in Providence. The license plate number is 58JZ91.



Yesterday, workers at a Sunoco station, the Motel 6 and The Amazing Superstore, confirmed that state police on Tuesday had shown them photographs of Ms. Corey and Mr. Webster. A cashier at the Sunoco station was familiar with Ms. Corey and asked if she was in trouble. She said Ms. Corey frequented the store but had not been in recently.



A worker at Motel 6 said Ms. Corey had been staying in Room 214 for “four or five days” and left abruptly on March 13 without paying for her final night. He said she did not normally have a car and instead arrived and left by taxi.



A photograph gleaned from the motel’s security camera allegedly shows Mr. Howze entering the building on March 10 carrying a McDonald’s bag and another large plastic bag. Workers at nearby businesses said patrons from the motel often walk to the fast food shop and the Walmart or the Sunoco. A manager at the McDonald’s restaurant said he’s spoken with police but he did not know any of the people in the photographs.



Mr. Sarli said his nephew had once worked repairing watches at a local mall and after being unemployed for a few months, was planning to work at the bakery.



“I was looking forward to that,” Mr. Sarli said. “We’re like a big family here and it would have been nice. He would have worked here forever.”



Instead now he and his family are just hoping Mr. Webster “will be brought home.”



He said no matter the outcome, the family wants to have some sort of closure and he is hoping state police detectives working on the case will be able to provide that.