Some girls at La Guardia HS of Music & Art and Performing Arts were not amused that a boy stole their stiletto-heeled thunder and became this year’s prom queen — and their claws have come out on social ­media.

“I know I go to LaGuardia because a boy won prom queen,” snarked Asia Pierre in a Facebook post that attracted 500 homophobic comments and 100 shares before it was removed.

“It just sucks that men win everything and we thought we at least deserve that,” wrote a classmate under the name Taj Mahal.

Matthew Crisson, an 18-year-old Staten Islander who self-identifies as “non-binary” (meaning neither male nor female), was awarded the tiara at the “Fame” school last weekend.

“It was a big deal for me to reach out to everyone and run,” Crisson told The Post.

Mona Davids, a LaGuardia parent who saw the negative Facebook post and coments, notifying the school and the Department of Education’s new LGBTQ community ­liaison.

“They were very catty and negative comments about something so wonderful and positive,” Davids said. “It was very alarming to me, considering what happened in Orlando and how these things can get out of hand.”