Bob Weinstein is fighting to remain at the studio, but some stakeholders believe he must leave, according to two people with knowledge of the matter, who spoke on the condition of anonymity to discuss private conversations. Bob Weinstein, who told The Hollywood Reporter on Saturday that he did not know “the extent” of his brother’s actions, did not respond to a request for comment.

In turning to Colony, the Weinstein Company and its advisers at the investment bank Moelis & Company are reaching out to a firm with experience in Hollywood. But some longtime media investors, noting the seriousness of the allegations against Harvey Weinstein, questioned what could be done with such a toxic asset.

“I don’t think you can sell this company with all the litigation you’re looking at,” said Amir Malin, the founder of Qualia Capital, a media investment firm. Mr. Malin was referring to both pre-existing commercial lawsuits and the vast number of potential lawsuits related to Harvey Weinstein’s sexual behavior.

Work has been underway in Hollywood to end partnerships with the studio. Amazon pulled the plug late Friday on a major television deal. At the same time, agents say they have been pressing the Weinstein Company to sell finished or near finished films like “The Upside,” a comedy starring Kevin Hart and Nicole Kidman, and “Mary Magdalene” starring Rooney Mara; many of the stars involved with those projects want nothing to do with the Weinsteins.

The Weinstein Company, already struggling in recent years because of box office misfires, has been imploding since investigations by The New York Times and The New Yorker revealed sexual harassment and rape allegations against Harvey Weinstein going back decades. Over the last week and a half, more than 30 women have come forward publicly with harrowing stories of encounters with him. Police in New York and London have started looking into some claims against Mr. Weinstein, who has denied “any allegations of nonconsensual sex.”