A horrific crash involving two cars in Point Cook has left three people dead and one fighting for life on Christmas Eve.

Police said an Audi travelling north well in excess of the 70km/h speed limit veered on to the wrong side of Palmers Road, slamming into a Honda Jazz carrying two women.

Police at the scene of the Point Cook crash. Credit:Jane Gilmore

The Audi was travelling so fast that when it hit a road barrier the engine was forced from the car and the battery was found 100 metres down the road.

The two vehicles collided on Palmers Road nears Whistler Crescent just after 7.30pm.