President Donald Trump repeatedly told top administration officials he wanted the US to pull out of the World Trade Organization — another sign of his antipathy to multilateral trade agreements, a report said Friday.

“He’s [threatened to withdraw] 100 times. It would totally [screw] us as a country,” a source who discussed the subject with Trump told Axios.

The source added that Trump has frequently told advisers, “We always get f–ked by them [the WTO]. I don’t know why we’re in it. The WTO is designed by the rest of the world to screw the United States.”

During the campaign, Trump told NBC News in July 2016 that the “World Trade Organization is a disaster.”

Aides have tried to explain to the president that the US benefits from belonging to the WTO, given that America created the system, the website reported.

The “Economic Report of the President” for 2018, which bears Trump’s signature on Page 11, states: “The United States has won 85.7 percent of the cases it has initiated before the WTO since 1995, compared with a global average of 84.4 percent. In contrast, China’s success rate is just 66.7 percent.”

Trump has already withdrawn from the Trans-Pacific Partnership and has railed against NAFTA, which he wants to renegotiate.

The president has also engaged in a war of words over trade with the EU, China, Japan, Mexico and Canada, and slapped steep tariffs on imported steel and aluminum — prompting retaliatory levies from America’s trading partners.

A US withdrawal from the WTO could cause chaos in global markets and cast doubt on trillions of dollars of trade.

A top trade lawyer in Washington told Axios: “We think he’s nuts, but not that nuts.”

But in an interview with Fox Business Network, Treasury Secretary Steven Mnuchin on Friday denied the report that Trump has suggested that he wants the US to withdraw from the WTO.

“There’s no breaking news here,” Mnuchin said. “So anybody who is reporting an Axios story is breaking news, it’s not right. I won’t use our favorite word ‘fake news.’ But this is an exaggeration.”