U.S. stocks opened lower on Tuesday, suggesting the recent spate of selling was not yet over as investors continued to fret over what impact inflation might have on equities going forward. The Dow Jones Industrial Average DJIA, -0.87% fell 250 points, or 1%, to 24,100. The blue-chip average is coming off its biggest one-day percentage drop since August 2011, as well as the largest point drop in its history. The S&P 500 SPX, -1.11% lost 33 points, or 1.3%, to 2,615. The Nasdaq Composite Index COMP, -1.07% lost 73 points to 6,893, a decline of 1% that pushed it into negative territory for the year. The S&P is also coming off its biggest percentage decline since August 2011, and Monday's selling pushed both the Dow and the S&P into negative territory for the year. Tuesday is on track to be the fourth straight negative session for the S&P and the Nasdaq, as well as the third straight down day for the Dow. The weakness was sparked by a stronger-than-expected jobs report last week, which suggested the Federal Reserve could be more aggressive than previously expected in raising interest rates, which added a new element of uncertainty into the market's inflation outlook. The selling on Tuesday was broad based, with all of the 11 S&P 500 sectors lower on the day, although technology was among the biggest decliners, off 1.7%. In company news, General Motors GM, -1.31% rose 2.5% after it reported fourth-quarter earnings that topped expectations.