Senate Majority Leader Mitch McConnell Addison (Mitch) Mitchell McConnellGOP ramps up attacks on Democrats over talk of nixing filibuster MLB owner: It's 'very necessary' to vote for Trump Delta: Early departures saved flight attendants' jobs MORE (R-Ky.) has scheduled a vote at 6:30 a.m. Friday, an unusually early time, to advance Betsy DeVos’s nomination to serve as secretary of Education.

Senate Republicans say they are getting fed up with Democratic obstruction and the extra early vote will allow them to get a head start in running time off the procedural clock.

McConnell is confident he will have the 51 votes he needs Friday to end debate on DeVos.

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Early morning votes are an extreme rarity in the Senate. One memorable instance took place the day before Christmas, 2009, when Democrats passed ObamaCare shortly after 7 am on a party-line vote of 60 to 39.

While two Republicans, Sens. Susan Collins Susan Margaret CollinsGOP short of votes on Trump's controversial Fed pick Congress must save the Postal Service from collapse — our economy depends on it Garcetti: I would have acted sooner if Trump hadn't downplayed virus MORE (Maine) and Lisa Murkowski Lisa Ann MurkowskiGOP ramps up attacks on Democrats over talk of nixing filibuster OVERNIGHT ENERGY: House Democrats tee up vote on climate-focused energy bill next week | EPA reappoints controversial leader to air quality advisory committee | Coronavirus creates delay in Pentagon research for alternative to 'forever chemicals' House Democrats tee up vote on climate-focused energy bill next week MORE (Alaska), will ultimately oppose DeVos, they will vote with their GOP colleagues on the procedural question of ending dilatory debate.

Senate rules require that 30 hours elapse after the Senate has voted to cut off a filibuster before a vote on final passage can be held.

By voting at 6:30 a.m., Republicans have a chance of confirming DeVos by late Monday but if Democrats drag out the post-cloture debate for the full 30 hours, it could lag intoTuesday.

McConnell and other GOP leaders are confident that there will be no other Republican defections on DeVos. They expect she will win confirmation next week with 51 votes after Vice President Pence weighs in to break an expected tie.