I recently finished two excellent books (The Biology of Cancer and The Death of Cancer) that really helped me start to understand the “big picture” of cancer research (in the lab AND the clinic). These books inspired us to piece together a timeline on the history of cancer therapy which ended up being a bit larger than we expected. Click on the image above for a PDF of our Cancer Therapy Poster (3′ x 1′). Below you can find a summary of all the abbreviations and references used for this project.

ABBREVIATIONS:

Yellow Highlighting – commonly used at the time

– commonly used at the time Green Highlighting – gene targeted by targeted therapies

– gene targeted by targeted therapies Red Highlighting – drug-resistant cancer that therapy is used for

– drug-resistant cancer that therapy is used for Blue Highlighting – cancer type genetic markers

– cancer type genetic markers “Dox” – doxorubicin

– doxorubicin “CyP” – cyclophosphamide

– cyclophosphamide “5FU” – 5-fluorouracil

– 5-fluorouracil “MTX” – methotrexate

– methotrexate “PSA” – Prostate Specific Antigen

– Prostate Specific Antigen “EGFR” – Epidermal Growth Factor Receptor

– Epidermal Growth Factor Receptor “Cisplat” – cisplatin

– cisplatin “vincris” – vincristine

– vincristine “TSG” – Tumor Suppressor Gene

– Tumor Suppressor Gene “MitC” – mitomycin C

– mitomycin C “chlrmb” – Chlorambucil

– Chlorambucil “Bleo” – Bleomycin

– Bleomycin “TMZ” – Temozolomide

– Temozolomide “NHL” – Non-Hodgkins Lymphoma

– Non-Hodgkins Lymphoma “HL” – Hodgkins Lymphoma

– Hodgkins Lymphoma “NSCLC” – Non-Small Cell Lung Canger

– Non-Small Cell Lung Canger “SCLC” – Small Cell Lung Cancer

– Small Cell Lung Cancer “CLL” – Chronic Lymphocytic Leukemia

– Chronic Lymphocytic Leukemia “AML” – Acute Myeloid Leukemia

– Acute Myeloid Leukemia “APL” – Acute Promyelocytic Leukemia

REFERENCES:

Weinberg, R.A. The Biology of Cancer (2nd ed.) , 2014 , Garland Science.

, , Garland Science. DeVita, V.T.; DeVita-Raeburn, E. The Death of Cancer (2nd ed.) , 2015 , Sarah Crichton Books.

, , Sarah Crichton Books. Cancer Progress.Net Progress and Timeline

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