Based on revenue estimates, the Star Trek franchise, created by Eugene Wesley "Gene" Roddenberry (USA, 1921–1991), is the most successful science-fiction brand originating on TV, worth in excess of $6 billion. This figure comprises revenue from syndication and DVD/home-video sales from 726 TV episodes, a worldwide movie gross of $1.73 billion from 13 films, an estimated 70 million books in print, 88 videogame titles with sales of more than 1.6 million units from the top 10 titles alone, and numerous toy and game licences.

The original 1966 Star Trek TV series began syndication almost immediately after the third season was cancelled in 1969.