WASHINGTON -- The Senate approved sweeping health-overhaul legislation on Thursday, a landmark moment for White House-led efforts to expand insurance coverage to more than 30 million Americans.

The bill, approved by a 60-39 vote, would deliver on a long-promised Democratic goal of extending coverage to nearly every American, and would represent the biggest expansion of the federal safety net since the 1965 creation of Medicare, the health-insurance program for the elderly and disabled.

Thursday's...