Two hospitals have been hit in suspected Russian air strikes in northern Syria, killing at least 20 people and wounding dozens.

At least seven people have been killed after a hospital in Marat Al Numan, Idlib was hit on Monday, Doctors Without Borders (also known by its French acronym MSF) who support the medical centre have said. Eight members of staff have also disappeared - it is not known if they are dead or alive.

In the neighboring Aleppo province, a missile hit a children's hospital in the town of Azaz, killing at least five people and wounding dozens. In a nearby village, an air raid also hit a school, killing seven others.

The 30-bed hospital in Idlib was hit four times in two series of at least two attacks within a few minutes of each other on Monday, MSF said.

Massimiliano Rebaudengo, MSF’s Head of Mission, told the Independent: “This appears to be a deliberate attack on a health structure, and we condemn this attack in the strongest possible terms.

“The destruction of the hospital leaves the local population of around 40,000 people without access to medical services in an active zone of conflict.

An MSF spokeswoman previously said: "We can confirm that an MSF-supported structure in Marat Al Numan in Idlib, northern Syria was destroyed this morning in air strikes. We are currently gathering more information about the attack but have nothing more to share as yet."

MSF have supported the hospital, which had 54 staff two operating theatres, an outpatients department and an emergency room, since September 2015.

The humanitarian medical organisation covered all the needs of the hospital including provision of medical supplies and running costs.

MSF International said over Twitter they believe four rockets were involved in the air strike.

The Britain-based Syrian Observatory for Human Rights said Russian warplanes targeted the hospital, destroying it and killing nine people. The Observatory, which tracks the casualties in Syria's five-year civil war, said dozens were also wounded in the attack.

Speaking by telephone from Maaret al-Numan, Tahya al-Sobeih, an opposition activist said: “The entire building collapsed to the ground.”

He added five people were killed near the clinic and “all members of the medical team inside are believed to be dead”. This has not been confirmed by MSF.

He said paramedics were now working to remove the rubble.

Alleged footage of the incident has been posted on social media, however MSF say the are unable to verify it.

Five people were killed and more than 30 were wounded in the missile attack on a second hospital in Azaz, the Observatory said. They added the dead include three children and a pregnant woman.

Activist Bahaa al-Halaby who is based in the northern city of Aleppo says it was a ballistic missile adding that it killed 10.

In Turkey, the private Dogan news agency reported that more than 30 of those wounded air strikes in Azaz,mainly children, were taken to a hospital in southern Turkey. Footage of ambulances arriving at the Kilis State hospital showed medical personnel unloading children on stretchers and a girl wrapped in a blanket.

The Observatory and al-Halaby also reported an air raid on the village of Kaljibrin near Azaz. Al-Halaby said the air raid hit a school, killing seven and wounding others while the Observatory said five were killed.

In pictures: Russian air strikes in Syria Show all 19 1 /19 In pictures: Russian air strikes in Syria In pictures: Russian air strikes in Syria Syrian boys cry following Russian air strikes on the rebel-held Fardous neighbourhood of the northern embattled Syrian city of Aleppo Getty In pictures: Russian air strikes in Syria Russian defense ministry spokesman Major General Igor Konashenkov speaks to the media in Moscow, Russia. Konashenkov strongly warned the United States against striking Syrian government forces and issued a thinly-veiled threat to use Russian air defense assets to protect them AP In pictures: Russian air strikes in Syria Syrians wait to receive treatment at a hospital following Russian air strikes on the rebel-held Fardous neighbourhood of the northern embattled Syrian city of Alepp Getty In pictures: Russian air strikes in Syria Russian Deputy Defense Minister Anatoly Antonov speaks at a briefing in the Defense Ministry in Moscow, Russia. Antonov said the Russian air strikes in Syria have killed about 35,000 militants, including about 2,700 residents of Russia AP In pictures: Russian air strikes in Syria Jameel Mustafa Habboush, receives oxygen from civil defence volunteers, known as the white helmets, as they rescue him from under the rubble of a building following Russian air strikes on the rebel-held Fardous neighbourhood of the northern embattled Syrian city of Aleppo Getty In pictures: Russian air strikes in Syria Civil defence members rest amidst rubble in a site hit by what activists said were airstrikes carried out by the Russian air force in the town of Douma, eastern Ghouta in Damascus, Syria Reuters In pictures: Russian air strikes in Syria A girl carrying a baby inspects damage in a site hit by what activists said were airstrikes carried out by the Russian air force in the town of Douma, eastern Ghouta in Damascus, Syria Reuters In pictures: Russian air strikes in Syria Civilians and civil defence members look for survivors at a site damaged after Russian air strikes on the Syrian rebel-held city of Idlib, Syria Reuters In pictures: Russian air strikes in Syria Civilians and civil defence members carry an injured woman on a stretcher at a site damaged after Russian air strikes on the Syrian rebel-held city of Idlib, Syria Reuters In pictures: Russian air strikes in Syria Volunteers from Syria Civil Defence, also known as the White Helmets, help civilians after Russia carried out its first airstrikes in Syria In pictures: Russian air strikes in Syria The aftermath of Russian airstrike in Talbiseh, Syria In pictures: Russian air strikes in Syria Smoke billows from buildings in Talbiseh, in Homs province, western Syria, after airstrikes by Russian warplanes AP In pictures: Russian air strikes in Syria Russian Air Forces carry out an air strike in the ISIS controlled Al-Raqqah Governorate. Russia's KAB-500s bombs completely destroy the Liwa al-Haqq command unit In pictures: Russian air strikes in Syria Caspian Flotilla of the Russian Navy firing Kalibr cruise missiles against remote Isis targets in Syria Â© TASS/ITAR-TASS Photo/Corbis In pictures: Russian air strikes in Syria Russia claimed it hit eight Isis targets, including a "terrorist HQ and co-ordination centre" that was completely destroyed In pictures: Russian air strikes in Syria A video grab taken from the footage made available on the Russian Defence Ministry's official website, purporting to show an airstrike in Syria In pictures: Russian air strikes in Syria A release from the Russian defence ministry purportedly showing targets in Syria being hit In pictures: Russian air strikes in Syria Russia launched air strikes in war-torn Syria, its first military engagement outside the former Soviet Union since the occupation of Afghanistan in 1979. Russian warplanes carried out strikes in three Syrian provinces along with regime aircraft as Putin seeks to steal US President Barack Obama's thunder by pushing a rival plan to defeat Isis militants in Syria In pictures: Russian air strikes in Syria Caspian Flotilla of the Russian Navy firing Kalibr cruise missiles against remote Isis targets in Syria, a thousand kilometres away. The targets include ammunition factories, ammunition and fuel depots, command centres, and training camps Â© TASS/ITAR-TASS Photo/Corbis

The strikes comes just days after Russia and other world powers agreed to a limited cessation of hostilities after talks in Munich.

A Russian Foreign Ministry official has reportedly said Russia will continue its air strikes around Aleppo even if a ceasefire agreement in Syria is reached, according to the Interfax news agency.

Syrian troops have been on the offensive in northern Syria under the cover of Russian air strikes over the past week. The ground offensive has been focused on the northern province of Aleppo while Monday’s air strike struck the clinic in near-by Idlib province.

Meanwhile in Brussels, European Union officials have called on Turkey to halt its military action in Syria after Turkish forces shelled positions held by a US-backed Kurdish militia over the weekend.