The chief executive of one of the world’s largest pharmaceutical companies has resigned from President Donald Trump’s manufacturing council in protest at his failure to condemn a white supremacist rally.

Kenneth Frazier, CEO of Merck, became just the latest business leader to resign in protest against the president’s policies, following announcements earlier this year that the heads of Uber, Disney and Tesla that they could no longer support Mr Trump's administration.

Mr Frazier said he was stepping down to take a stand against intolerance and extremism.