The search continues for a man wanted on capital murder for the slaying of a Birmingham woman, and authorities say it’s crucial he is quickly found.

Investigators believe Adam Jamal Isom fatally shot 47-year-old Cheri Twilley – possibly because she rebuffed his advances at a southwest Birmingham convenience store – and also wounded her adult son, who was hit twice and now recovering.

“Our main concern is public safety,’’ Birmingham homicide Capt. Joe Roberts said Thursday. “He has proven he is a killer. He is extremely dangerous.”

The U.S. Marshals Gulf Coast Regional Fugitive Task Force is assisting in the search for Isom.

The shooting happened shortly after 7:30 p.m. Monday in the 1600 block of Tuscaloosa Avenue. Brandon Twilley, 31, had driven his mother to the store to buy cigarettes and a drink when Cherie encountered Isom inside the store.

“They had a brief conversation, a civilized conversation,’’ Roberts said. “He was hitting on her. She smiled and walked out.”

Brandon said Isom exited the store and approached them again when his mother had gotten in the vehicle. “I couldn’t understand what he was saying to her, but he was mad because my mom didn’t want to talk to him,’’ he said. “He showed a gun and said he was going to kill both of us.”

Brandon pulled off. Isom first pulled up behind his vehicle, and then alongside of him. “He let his window down and he said something real smart and foul,’’ Brandon said. “Then he started firing shots.”

Brandon, the closest to Isom, was shot in the arm and in his top and bottom lip. “When I told her I got shot, she said she got shot,’’ he said. “He was still trying to chase us and shot at us again.”

Though injured, Brandon rushed to get his mother to the hospital. She had been struck in the side but was initially still conscious. “She was talking to me and holding her side,’’ she said. “I was talking to her, telling her to keep talking to me. I was going like 80 mph to get her to the hospital in time.”

Once at Princeton Baptist Medical Center, Cheri’s condition quickly deteriorated. “All of the sudden, she was shaking a little bit and then she collapsed and died,’’ Brandon said.

Brandon was one of Cheri’s six adult children. He said she was his heart and his world. “She was good to everybody,’’ he said. “She treated everybody like a son or a daughter.”

The family has started a GoFundMe to help with her funeral. Donations can be made here.

Roberts said the mother and son were shot with a .223 rifle. A search warrant of Isom’s home turned up multiple other weapons. Police recovered handguns, rifles and high-capacity semi-automatic machine guns. “We believe we have most of Mr. Isom’s weapons, but we don’t know that for a fact,’’ Roberts said.

Investigators have recovered the SUV he was driving when police say he carried out the shooting. They believe he may be in the West End area, and say others are likely helping him to hide.

Isom is charged with capital murder and attempted murder in Monday night’s incident. He also had been previously sought on multiple outstanding warrants. Roberts said Isom is suspected in other violent crimes.

“We expect to implicate him in other homicides,’’ he said. “We’re putting those cases together at this time.”

Because the shooting of Cherie was so senseless, Roberts said, they are concerned what he will do next. “There was no argument, nothing that even came close to justifying what this man has done,’’ he said. “Therefore, we’re concerned he’s going to attack another innocent victim. He needs to be off the streets quickly.”

Anyone with information on his whereabouts is asked to call Birmingham homicide detectives at 205-254-1764, Crime Stoppers at 205-254-7777 or 911.