The astronaut panel discussions are over and the green slime has been cleaned up marking the end of the World Science Festival in Brisbane.

The festival was initially held in New York in 2008 and this was the first time it was staged outside of the US.

More than 100 of the world's best scientific minds from nine different countries were involved with the event.

A Brisbane visitor tries out the infinity swing which generates electricity through movement. ( 612 ABC Brisbane: Jessica Hinchliffe )

Queensland Museum CEO and director, Professor Susan Miller, said the response from festival-goers had been nothing but positive.

"It's been unbelievable and we have been thrilled with the response," she said.

"There's clearly an appetite for science here in Queensland.

"We nearly sold out across the entire program and hundreds of people took advantage of the free street science we offered over the weekend."

Queensland Museum's Dr Andrew Rozefelds helps visitors find fossils in the rubble at the World Science Festival. ( 612 ABC Brisbane: Jessica Hinchliffe )

Professor Miller said securing the festival involved a year of negotiations.

An agreement was reached in May 2015, meaning the World Science Festival will be staged in the river city for the next six years.

"We wanted to create a high-end celebration of science and we loved the New York model so I got on a plane and went and asked them," Professor Miller said.

"No-one had ever asked them before so they said yes!"

Science Steve and his robot Meccano showed how voice activated robots can now dance, move and help in everyday routines. ( 612 ABC Brisbane: Jessica Hinchliffe )

Street science performers at South Bank over the weekend encouraged families to interact with science.

Professor Miller hoped the variety in the festival program would keep people of all ages inspired long after the festival.

Visitors play the periodic table of elements battleship game at South Bank. ( 612 ABC Brisbane: Jessica Hinchliffe )

"People have seen everything from live turtle hatchings to playing with dinosaurs in virtual reality," Professor Miller said.

"There's been something for everyone ... even for people who didn't have an interest in science."

Australian astronaut Andy Thomas, Columbia University Professor Brian Green and Alan Alda were popular with festival-goers.

Young budding minds help a University of Queensland student conduct an experiment. ( 612 ABC Brisbane: Jessica Hinchliffe )

"It's been extraordinary to have these top people in the world of science," Professor Mille said.

"If someone's inspired by that, we hope they come back.

"The opportunity to create these memories for people ... that's what brings people back."

Queensland Museum's Dr Robert Raven with a golden orb spider at South Bank. ( ABC Brisbane: Jessica Hinchliffe )

Professor Miller said the challenge was to keep people excited over the next 12 months until the 2017 World Science Festival.

"We want to keep that momentum going," she said.

"It's what excites our younger generation and makes them want to be scientists and engineers and NASA astronauts"