OTTAWA — About 3,000 locomotive engineers and conductors at the Canadian Pacific Railway walked off the job Sunday morning in a dispute over wages and benefits.

Although the company said it would try to maintain some service by using managers, the strike is likely to disrupt major industries throughout North America, including automakers, oil companies, paper businesses, lumber suppliers and agriculture and mining companies.

In a news release issued immediately before the strike, the Teamsters Canada Rail Conference suggested that disagreements on rest time and other scheduling issues had led to the breakdown in negotiations.

“We require sufficient fatigue countermeasures to protect our members’ safety and health,” the statement said.