A woman was backed into a corner before being attacked by a crocodile at a north Queensland wildlife sanctuary, paramedics say.

Renee Robertson was working at the Billabong Sanctuary at Nome, south of Townsville when a 2.5-metre croc struck her in its pen around 1.30pm on Monday.

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This is the scary moment 'Tipper' can be seen eyeing off wildlife worker, Renee Robertson. Photo: 7 News

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Renee Robertson's terrifying screams ring out as a colleague beat the crocodile off Ms Robertson as other workers pulled her to safety. Photo: 7 News

The 25-year-old handler's arm suffered from severe injury and she was immediately transported to Townsville hospital in a serious condition.

In the shocking video, the crocodile - known as Tipper - can be seen eyeing off Ms Robertson and running toward her.

The reptile's powerful jaws clamped her arm and the animal dragged her to the ground.

Her terrifying screams of pain can be heard as another staff member beats the crocodile off with a stick, while a worker drags her from the scene.

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Co-workers say Renee Robertson is in expert in animals. Photo: 7 News

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