Firefighters have been working throughout the night to tackle a huge blaze at a cancer research centre in Manchester's Christie Hospital .

Large numbers of crews from across the region remain at the scene and have been battling the flames for almost 24 hours, after fire broke out in the roof of the Paterson Building, on Wilmslow Road, Withington , at 10.30am on Wednesday.

Overnight a number of relief crews working in shifts have taken over, wearing breathing apparatus to continue to fight pockets of fire in the roof.

Firefighters, working alongside officers from the Christie, have also been able to salvage a number of high value items to help preserve the important work of cancer research scientists.

Wilmslow Road remains shut in both directions, between Palatine Road and Lapwing Lane, while the firefighting operation continues.

Patients at the hospital are advised to still attend appointments, but to use the Palatine Road entrance to the hospital.

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