A woman in her 60s has died after being struck by a car while crossing the road in Northcote, in Melbourne's north.

The woman was crossing Separation Street on Tuesday morning when she was struck by a car turning right from High Street, according to Victoria Police. The incident occurred near Northcote Plaza shopping centre.

The woman was taken to Royal Melbourne Hospital and later died from her injuries.

The area remains closed to traffic while police from the major collision unit investigate the accident.

This death takes the 2015 road toll up to 102, according to Victoria Police. The toll at the same time last year was 92.

