CHARLOTTE, N.C. — A woman has been found dead in the remains of a home leveled by a fire and explosion in North Carolina's largest city.

Charlotte Fire Department Battalion Chief Matt Westover told reporters that the woman's body was found Tuesday night, nearly seven hours after the blast was reported by a man trapped in the home.

Fire Chief Reginald Johnson said the man was able to tell operators where he was in the home, but didn't say what caused the blast. He was flown to a hospital with life-threatening injuries. Westover said the man also told operators where the woman may have been trapped. Westover declined to say if the woman was a resident of the home, citing the pending investigation.

Matt Roberts, chief executive of Raleigh General Hospital in Beckley, West Virginia, told WSOC-TV that the man is a hospital cardiologist named Jebran Karam. Roberts said Karam and his wife bought the Ballantyne home in 2015.

Area resident Paul Aarons told The Charlotte Observer his entire house shook and he heard a massive boom. The blast seemed so close that he thought someone was driving into his garage.

Aerial coverage showed wood scattered at the site and debris blown into the adjacent street as well as into some surrounding trees and nearby yards. Firefighters used a ladder truck to get closer to the flames that erupted from the explosion.

Westover said other homes in the vicinity were safe, but some homes nearby received significant damage. An emergency medical services agency, Charlotte Medic, told news outlets that two people living in surrounding homes were being evaluated for injuries that weren't considered life-threatening.

Westover said more than 80 firefighters were at the scene and seven were treated for dehydration. Reports indicated firefighters arrived in full gear but later were down to their T-shirts as they worked amid the rubble in scorching heat. Temperatures in Charlotte by Tuesday afternoon had climbed into the 90s.