It's kinda meant to be open for interpretation, I didn't really think of any particular event where Tyrael might've held his Soulstone in his hands, but it can been for around that time, yes.



I was just thinking of a scenario like "what if Diablo's Soulstone actually wasn't destroyed" when I added the Soulstone. And since it's not for sure in this painting what Tyrael is doing with the stone, there kinda is the element of possible corruption there.