No, but orange females are rare. The simple answer is that an orange female cat must have BOTH an orange father and either an orange or calico mother. Where as an orange male only needs ONE parent to be orange or calico.

two

To understand why, you'll need a small lesson in genetics: The gene that determines orangeness is carried on the X chromosome. (females have two X chromosomes, X X, and males have an X and a Y, X Y) For our purposes, we will represent an orange gene carrying chromosome as "X^C" and a non-orange chromosome simply as "X" A male orange cat must have an orange X, so his chromosome pair is "X^C Y" (as opposed to a non-orange male "X Y") In order for a female cat to be orange, she must haveX^C chromosomes. "X^C X^C" Now, offspring get their chromosomes from their mother and father. A female gets an X from mom and an X from dad. A male must get an X from mom, and a Y from dad. So the female cat, in order to be orange, must have an orange (X^C Y) father and a mother that at least carries one X^C chromosome. A female cat with one orange chromosome (X^C X) only partially shows or expresses her orange gene and is a calico cat. If you find this interesting and want to get a better understanding of how chromosomes are passed to offspring, I suggest you learn about Punnet squares and how they work. Plug different combinations of X^C into the parent slots and see what colors the offspring are. (it's good clean nerdy fun!)