Io does not have any clear spoken dialogue, but its reactions are generally conveyed through sounds which match musical patterns, which in turn are garnered from patterns of human speech. For example, it expresses happiness by producing sounds in a major key, when angry it produces a jarring, dissonant chord; and when in pain it shrieks.

Drafting

Picked

Banned

Entering battle

Benevolent Companion

Taunting

Beginning battle

Moving

6 seconds cooldown

Attacking

6 seconds cooldown

Leveling up

Killing an enemy

10% chance

Benevolent Companion

First Blood

Benevolent Companion

Meeting an ally

During earlygame, within 1000 radius

Last hitting

60 seconds cooldown

Denying

Requires visible enemy player within 1000 radius, 60 seconds cooldown

Acquiring an item

Acquiring a specific item

Dying

Respawning

Benevolent Companion

Reincarnating

Bottling Runes

Activating runes

Arcane Rune and Bounty Rune

Benevolent Companion

Ability on cooldown

First attempt within 10 seconds

Second attempt within 10 seconds

Third and more attempts within 10 seconds

Not enough mana

First attempt within 10 seconds

Second attempt within 10 seconds

Third and more attempts within 10 seconds

Taking damage

3 seconds cooldown

Selecting

5 consecutive clicks on the hero

Chat responses

Thanking

thx, thanks, ty, or ally casts certain spell on player, 30 seconds cooldown

Laughing

/laugh, haha, lol, 15 seconds cooldown

Match end

Won

Lost

Cosmetic item drop

Misc

Wizard