Marco Rubio Marco Antonio RubioFlorida senators pushing to keep Daylight Savings Time during pandemic Hillicon Valley: DOJ indicts Chinese, Malaysian hackers accused of targeting over 100 organizations | GOP senators raise concerns over Oracle-TikTok deal | QAnon awareness jumps in new poll Intelligence chief says Congress will get some in-person election security briefings MORE took aim at Donald Trump Donald John TrumpHR McMaster says president's policy to withdraw troops from Afghanistan is 'unwise' Cast of 'Parks and Rec' reunite for virtual town hall to address Wisconsin voters Biden says Trump should step down over coronavirus response MORE’s manhood during a rally Friday morning, portraying the GOP front-runner as a coward and suggesting he may have wet himself during Thursday night's presidential debate.

"He called me Mr. Meltdown. Let me tell you something, last night during two of the debates, he went backstage, he was having a meltdown," Rubio said in Dallas.

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"First, he had this little makeup thing applying makeup around his mustache because he had one of those sweat mustaches. Then, he he asked for a full length mirror … maybe to make sure his pants weren’t wet."

The line came as Rubio took out his cellphone and began to read Trump's tweets from stage. Noting that some had misspellings, he cracked that the billionaire businessman "must have hired a foreign worker to do his own tweets."

He chided Trump for trying to portray himself as a "tough guy" and said voters shouldn’t be fooled.

"This is a con-job where he is going to Americans who are struggling, Americans who are hurting, and he’s implying, 'I'm fighting for you' because he’s a tough guy. A tough guy? This guy inherited $200 million, he’s never faced any struggle," Rubio said.

“The other day, he told somebody, a protestor, 'I'm going to punch you in the face.' Donald Trump has never punched anyone else in the face. Donald Trump was the first guy to beg for Secret Service protection.”

The attacks come the morning after a surprisingly contentious debate, hosted in Houston by CNN, that largely pitted the Florida senator against Trump in a series of attacks. The GOP race pivots to Super Tuesday in just days, when one-quarter of the race's total GOP delegates are up for grabs.