Comedy is king on Twitter. Professional humorists and armchair standups alike have amassed legions of followers that hang on every 140-character quip.

Twitter humor is a brand-builder, a great writing exercise, and if you're really good, it might even land you a job (but probably not, so settle down).

SEE ALSO: How Twitter Is Changing the Craft of Comedy

So, what does it take to get laughs at this 24/7 digital cocktail party? We asked some of the funniest tweeters around for their tips on cracking wise in the one-liner Renaissance.