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United Nations judges are set to hand down their decisions in the appeal by former Bosnian Serb leader Radovan Karadzic against his convictions and 40-year sentence for masterminding atrocities in his country's devastating 1992-95 war.

Karadzic appealed his 2016 convictions for genocide, crimes against humanity and war crimes, as well as his sentence. Prosecutors appealed his acquittal on a second count of genocide during Europe's bloodiest conflict since World War II.

Relatives of victims of the war gathered outside the courtroom Wednesday ahead of the hearing that will announce the decisions.

Karadzic is one of the most senior figures tried by the Hague war crimes court. His case is considered as key in delivering justice for the victims of the conflict, which left over 100,000 people dead and millions homeless.