Celestamine (Generic: Betamethasone) belongs to a group of drugs known as corticosteroids. It is manufactured and marketed by Schering Plough Limited (Under – Merck Sharp and Dohme LLC).

Celestamine tablets contain a medicinal mixture of two components betamethasone and dexchlorpheniramine. The composition of these two components in each tablet is below:

Betamethasone: 250 mcg per tablet

Dexchlorpheniramine Maleate – 2 mg per tablet

It is used for allergic disorders, itching or rash, dermatitis, ataxia telangiectasia, psoriasis of the scalp, ulcerative colitis, arthritis, phimosis, and other diseases.

Celestamine Uses

Celestamine Tablet is used to treat, control, prevent, and improve the following diseases, conditions, and symptoms:

Breathing disorders

Itch or rash

Allergic disorders

Skin inflammation

Ataxia telangiectasia

Cerebral edema

Scalp psoriasis

Arthritis

Ulcerative colitis

Phimosis

Hematologic disorders such as Acquired(autoimmune) hemolytic anemia, Diamond-Blackfan anemia, idiopathic thrombocytopenic purpura in adults.

Blood disorders.

Celestamine Mechanism

Celestamine is a combination of anti-inflammatory and anti-allergic medications.

Betamethasone is a drug with corticosteroids, sometimes referred to as a steroid. Steroids reduce the number of inflammatory chemicals your body produces. They also reduce the body’s natural immune response, which helps to control inflammation.

while dexchlorpheniramine maleate has antihistamine properties.

Celestamine Side Effects

The more common side effects that can occur with Celestamine include:

Problems with your vision;

swelling, rapid weight gain, feeling short of breath;

severe depression, unusual thoughts or behavior, seizure (convulsions);

Bloody or tarry stools,

Coughing up blood;

Sedation and drowsiness

Fluid and electrolyte disturbance in the body

Muscle weakness, loss of muscle mass, tendon rupture.

Congestive heart failure in susceptible patients

Osteoporosis, pathological fractures

Peptic ulcers, irregular bowels, nausea, vomiting

Skin discoloration (Blue skin color).

Impaired healing of wounds

Swelling of your face, lips, tongue, or throat.

Seizure

Abdominal distention.

Thin and fragile skin.

Increased sweating, urticaria.

Vertigo, headaches.

Euphoria, mood swings, depression.

Menstrual irregularities

Infection. Signs may include cough, fever, chills.

Precautions

Before you taking Celestamine to tell your doctor If you have an allergy to betamethasone or any other part of betamethasone preparations.

Tell you, Doctor, If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.

Celestamine is not suitable for infants.

Before taking Celestamine Tell Your Doctor If you have any of these health problems: A fungal infection or malaria infection in the brain and herpes infection of the eye.

If you have nerve problems in the eye.

Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take betamethasone oral solution with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.

Should not use celestamine for a prolonged time.

Celestamine In Pregnancy & Breastfeeding

The FDA has assigned pregnancy category C betamethasone. Studies in animals have shown evidence of teratogenicity when oral corticosteroids are administered or potent steroids are administered topically. There are no controlled data in human pregnancy. Betamethasone has been shown to cross the placenta. Betamethasone is recommended only during pregnancy when there are no alternatives and the benefits outweigh the risks.

Celestamine is not safe to take if you are breast-feeding or intending to start breastfeeding. The corticosteroid can damage the fetus or a baby. This can also disrupt the normal growth of a newborn baby. Always consult a health care professional before using Celestamine if you are breast-feeding a baby.

Celestamine interactions

If you use other medications or over the counter products in precisely the exact same time, the effects of Celestamine Tablet can alter. This might increase your chance for side-effects or trigger your medication to not operate correctly. Inform your doctor about all of the medications, vitamins, minerals, and herbal supplements you’re using, so your physician can help you prevent or handle drug interactions. Celestamine Tablet may interact with these drugs and products:

Estrogen

Phenobarbital, Phenytoin, rifampicin or ephedrine

Potassium-depleting diuretics can increase the chances of hypokalemia.

Cardiac glycosides can improve the chance of arrhythmias or digitalis toxicity associated with hypokalemia.

Coumarin-type anticoagulants can increase or reduce the anticoagulant effects.

Corticosteroids may improve the potassium depletion brought on by amphotericin B. In most patients taking at least one of these drug treatment mixes, serum electrolyte determinations, especially potassium levels, must be tracked carefully.

Dosage adjustments of antidiabetic medication may be mandatory if corticosteroids are given to diabetics. The activity of oral anticoagulants could be inhibited by antihistamines

Corticosteroids may reduce blood salicylate concentrations. Acetylsalicylic acid ought to be used cautiously in conjunction with corticosteroids in hypoprothrombinemia.

Celestamine can also interact with digoxin and cyclosporine etc.

Celestamine Dosage

The usual recommended dose of Celestamine for adults is 2 to 6 tablets per day. As the patient improves, the dosage should be gradually reduced to the minimum required. The drug should stop whenever possible.

Your doctor will determine the right dose for you based on your individual needs. Your overall health can affect your dose. Tell your doctor about all the health conditions you have before your doctor or nurse gives you the medicine.

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Frequently Asked Questions

1. Should I use Celestamine Tablet on an empty stomach before or after meals?

Answer: Celestamine should be used daily as directed by your healthcare practitioner. Generally, it is used after meals and at bedtime.

2. What is Celestamine used to treat?

Answer: Celestamine Tablet is used to treat, control, prevent inflammation, allergic reactions, skin rashes, and many other conditions. Check Uses above.

3. Is it safe to use Celestamine Tablet if you are pregnant?

Answer: It is a Category C drug. There are no controlled data in human pregnancy. Betamethasone has been shown to cross the placenta. Betamethasone is recommended only during pregnancy when there are no alternatives and the benefits outweigh the risks. Consult your doctor for specific recommendations for each case.

4. Is Celestamine Tablet Safe During Breastfeeding?

Answer: It is not safe to take if you are breast-feeding or intending to start breastfeeding. The corticosteroid can damage the fetus or a baby. This can also disrupt the normal growth of a newborn baby. Consult your physician.

5. Can Celestamine Tablet be used for itching or rashes and allergies?

Answer: Yes, itching or rash and allergy are among the most commonly used applications reported for Celestamine Tablet. Always ask your GP before using it for any condition.

6. Is it safe to handle or operate heavy machinery when using this product?

Answer: You should not drive if you use the medicine, make you drowsy, dizzy or your blood pressure goes down. Always ask your doctor about recommendations for your body and your health conditions.

7. Can I stop using Celestamine immediately, or should I stop using it slowly?

Answer: Some medications can not be stopped immediately due to rebound effects. Consult your doctor for recommendations on your body, health, and other medicines you may use

8. Is this substance or addictive product, or is it a habit?

Answer: No it is not addictive.

9. Is this steroid?

Answer: Yes, It contains Betamethasone which belongs to a group of drugs known as a corticosteroid.

10. What to do if I missed a dose of Celestamine?

Answer: If you miss a dose of celestamine, take it as soon as possible. However, if it is almost time for the next dose, skip the missed dose and take your usual dose as planned. Do not take a double dose.

11. What should I do in an emergency or overdose of Celestamine?

Answer: In case of an emergency or overdose, consult your local ambulance or go to the nearest emergency room.

12. How should I take Celestamine?

Answer: The usual dose for adults is 2 to 6 tablets per day. As the patient improves, the dosage should be gradually reduced to the minimum required. Always consult your physician before taking the drug.

13. Is Celestamine an antihistamine?

Answer: No, It contains Betamethasone as an active ingredient which belongs to a group of drugs known as corticosteroids.

14. What are the side effects of Celestamine?

Answer: The most common side effects of this drug include headache, nausea, sleep disturbances, Gastric ulcer, poor appetite, Diarrhea, and others. This is not a complete list of side effects. For more check above.

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