The Heat have successfully defended their Women's Big Bash League (WBBL) crown with a comfortable six-wicket win over Adelaide Strikers at Allan Border Field in Brisbane.

Key points: The Heat brought up the winning run with 11 balls to spare in front of a sell-out crowd

The Heat brought up the winning run with 11 balls to spare in front of a sell-out crowd Beth Mooney dominated with the bat for the Heat with 56 not out from 45 balls

Beth Mooney dominated with the bat for the Heat with 56 not out from 45 balls The Strikers had made 7-161 from their 20 overs

Heat opener Beth Mooney was outstanding with the bat in front of a sell-out crowd, making an unbeaten 56 from 45 deliveries as the Heat successfully chased down the victory target of 162 with 11 balls to spare.

The Strikers, who made 7-161 from their 20 overs, gave themselves a glimmer of hope when they dismissed Jess Jonassen (33) and Grace Harris (2) to leave the Heat on 4-134 in their run chase.

But Mooney and Laura Harris (19 not out) put the foot down to ensure the Heat added a second WBBL title to last season's success.

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Harris scored the winning run to spark the celebrations, just as she did when the Heat upset the Sydney Sixers last summer.

The Heat's innings was sparked by an eventful fifth over when Sammy-Jo Johnson justified her promotion to number three as a pinch hitter.

Johnson belted four sixes, including three in three deliveries, off Strikers' all rounder Sophie Devine's second over.

While Johnson fell on the last ball of the over to give some relief to Devine, her 11-ball 27 had given the Heat the breathing space they needed to cruise to victory.

Mooney and Jess Jonassen (33) then showed their experience to steer the Heat within sight of the target with a 67-run third-wicket partnership off 49 deliveries.

Brisbane Heat opener Maddy Green looks for runs against Adelaide Strikers. ( AAP: Glenn Hunt )

Earlier, a counter-attacking innings by Amanda-Jade Wellington lifted the Strikers to their total.

The Heat sent the Strikers in and had immediate success when George Prestwidge (2-24) made the most of her elevation to use the new ball to have Devine caught for just 5.

The New Zealander, named player of the tournament during the week, top-edged Prestwidge to deep third man in the second over of the day.

That dismissal left Devine on 769 runs at 76.90 for the tournament, just eight behind Ellyse Perry's record tally for a season of 777 from last year's WBBL.

A 59-run second-wicket partnership between Tahlia McGrath (33) and Suzie Bates (27) steadied the Strikers, but the pair fell in quick succession to leave the Strikers at 3-67.

Mooney provided a highlight moment for the Strikers with an athletic stumping to remove Katie Mack (6) before Wellington's 55 off 33 deliveries guided her team from 5-93 and past 150.

ABC/AAP