It could be any night in a suburban 7-Eleven store - as CCTV shows customers queuing for milk and wandering though the aisles.

But this is Enmore, in Sydney's inner west, on Saturday night - and two customers are about to be hacked in the head in a brutal and seemingly random attack.

The first indication that anything is amiss is when a young blonde woman strolls in at around 2.20am holding a long-handled axe in her left hand.

This is the moment a blonde woman smashed two people in the head with an axe during a terrifying and seemingly random attack in a Sydney 7-Eleven

She appears calm as she approaches a man waiting in line and chats to him for around a minute before swinging the axe into his face.

As he collapses on the ground in shock, she brings the weapon up a second time before crashing it down on the back of another woman's head as she tries to leave.

The attacker then takes a second swing at the woman as she is sprawled on the floor, before strolling away as if nothing has happened.

As she leaves she can be seen taking a kitchen knife from the back pocket of her jeans and tossing it on the ground, footage obtained by News.com.au shows.

The man is Benjamin Rimmer, 32, who sustained major head injuries and is now in hospital in a serious but stable condition.

The second victim is 43-year-old Sharon Hacker, who was told by paramedics that only her thick dreadlocks saved her from having her head taken clean off.

The woman can be seen talking to a male customer for a full minute before swinging the axe into his face, then hacks another woman in the back of the head (pictured)

Police have arrested 24-year-old Evie Amati who has been charged with two counts of GBH and is being held in custody until her next court appearance on Thursday

And police allege that the attacker is Evie Amati, 24, a union organiser who is now in custody charged with two counts of grievous bodily harm with intent.

Amati did not apply for bail during her first court appearance, and was remanded in custody until her next hearing on Thursday.

However, she did request medication to treat depression as well as two hormone pills typically taken by transgender individuals transitioning from male to female.

She asked the court to supply her with Progynova and Spiractin, which boost oestrogen production and reduce testosterone, respectively, and Zoloft - an antidepressant, according to The Daily Telegraph.

Sharon Hacker, 43, who was hit in the back of the head during the attack, said paramedics told her if it weren't for her dreadlocks she'd be dead

Police were called to Enmore 7-Eleven (pictured) at around 2.25am before they arrested Amati a short distance away while she was carrying an axe

Police say they were called to reports of an attack inside a 7-Eleven store at roughly 2.25am on Saturday morning.

Officers say they arrested Amati on a nearby street with the axe in her possession, and later recovered a kitchen knife from the scene.