Cyclists want cars banned from sections of Chapel Street, one of Melbourne's busy shopping precincts.

Bicycle Network Victoria (BNV) want cars off the street in a bid to reduce the number of road accidents.

At least 91 cyclists have been hit by cars on the busy shopping strip since 2008.

BNV's Garry Brennan said the area has been "infested with cars" and a ban would keep both cyclists and pedestrians safe.

"It's one of the worst strips in Melbourne for bikes. It's narrow, there's lots of trams, there's an awful lot of short-term traffic movement," he said.

"So it's just always showing up in the stats as a really bad street for bike riders."

Mr Brennan said his plan would see entire blocks of Chapel Street cut off during certain periods of the day.

But City of Stonnington chief executive Warren Roberts said the council's cycling strategy catered for all road users.

"We encourage motorists and cyclists to be aware of safe cycling markings already installed in Chapel Street," he said.

"Stonnington Council works closely with Victoria Police to monitor and help reduce cyclist incidents on Chapel Street."