Two South Carolina children are dead, their father is hospitalized and their mother is accused of murder.

An autopsy report released by the Pickens County Sheriff’s Office on Wednesday said the children – Sawyer Simpson, 5, and Carly Simpson, 7, -- were shot multiple times, NBC station WYFF in Greenville, S.C., reported.

An arrest warrant obtained by the station shows that Suzanna Simpson, known as Anna, is charged with two counts of murder and attempted murder of her husband, Michael.

Suzanna Simpson was under guard at a Greenville hospital, the station reported.

Deputies responding to a vehicle crash in the tiny community of Dacusville just after 6 a.m. on Tuesday found a pickup truck on the side of the road with Anna Simpson behind the wheel, Pickens County Sheriff’s Office spokesman Creed Hashe told the station.

Using the registration document for the truck, deputies went to the Simpson home in the Cherokee Trail area of the town and found the children dead and their father, Michael Simpson, severely wounded.

Michael Simpson remains in critical condition with life-threatening gunshot wounds, according to the sheriff’s office.

Suzanna Simpson will be booked into county jail as soon as she is released from the hospital, the sheriff’s office said.

A representative with Pickens County Schools, John Eby, told the station Sawyer was a kindergartner and Carly was in first grade. Anna Simpson was a very active parent, Eby said.