Martha Stewart has ditched eBay, taking her American Made store to Amazon’s Handmade marketplace, as the e-commerce giant flexes its muscle in the burgeoning online market for handcrafted goods.

American Made, a venture introduced in 2013, was intended to be eBay’s answer to Etsy, the pioneer in the online handmade goods market. It offered locally made food, crafts and health and beauty products handpicked by Martha Stewart and her team at Martha Stewart Living, the media company she founded.

But both eBay and Ms. Stewart confirmed on Tuesday that they had decided to part ways.

Instead, American Made will go live on Wednesday on Amazon’s Handmade store, the arts-and-crafts marketplace the company set up last month. The new site has positioned Amazon as a formidable competitor to Etsy, which logged almost $2 billion in gross merchandise sales in 2014, and went public this year.

Since Amazon introduced Handmade, the number of artisans who list on the site has doubled to more than 10,000, according to Erik Fairleigh, an Amazon spokesman. The number of products for sale on Handmade has also jumped to 200,000 items, from an initial lineup of 80,000, he said.