Arin Andrews and Katie Hill do not look out of place in the new Barneys New York campaign. Both have nonexistent hips, are right in the ballpark of six feet tall and aren’t yet old enough for a legal drink. But there’s one marked difference between them and the models you ordinarily see on runways and in the pages of Vogue and Elle: Mr. Andrews, 17, was born a girl, and Ms. Hill, 19, a boy.

They are just two of nearly 20 transgender models photographed by Bruce Weber who will appear in the new Barneys catalog and magazine campaign, wearing clothes from designers like Ann Demeulemeester, Balenciaga, Lanvin and Manolo Blahnik.

Alongside photographs of the subjects, many taken with family members, pets and other members of their support networks, the catalog also features excerpts from interviews with the participants by the journalist Patricia Bosworth, a contributing editor at Vanity Fair and the biographer of Diane Arbus.

Ranging in age from 17 to “early 30s,” their races, socioeconomic positions and places on the transgender spectrum vary.