A new analysis of the GOP's latest bill to repeal and replace ObamaCare shows the bill hitting hardest in states held by holdout votes Sens. Lisa Murkowski Lisa Ann MurkowskiMcConnell locks down key GOP votes in Supreme Court fight Most Americans think winner of election should pick next Supreme Court justice: poll Murkowski: Supreme Court nominee should not be taken up before election MORE (R-Alaska) and John McCain John Sidney McCainMomentum growing among Republicans for Supreme Court vote before Election Day McConnell urges GOP senators to 'keep your powder dry' on Supreme Court vacancy McSally says current Senate should vote on Trump nominee MORE (R-Ariz.).

Axios reported Friday that an estimate from the Centers for Medicare and Medicaid Services (CMS) predicted Alaska would lose 38 percent of federal funding for premium subsidies and Medicaid by 2026 under the proposal to repeal ObamaCare.

Murkowski, who hasn't yet stated how she will vote on the Graham-Cassidy health care bill, is seen as a key target for the bill's co-sponsors, Sens. Bill Cassidy William (Bill) Morgan CassidyCoushatta tribe begins long road to recovery after Hurricane Laura Senators offer disaster tax relief bill Bottom line MORE (R-La.) and Lindsey Graham Lindsey Olin GrahamMcConnell locks down key GOP votes in Supreme Court fight Will Republicans' rank hypocrisy hinder their rush to replace Ginsburg? Momentum growing among Republicans for Supreme Court vote before Election Day MORE (R-S.C.). The two senators are reportedly considering changes to the bill specific to Alaska in order to win over her vote.

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Arizona, according to the study, would see its federal funding for Medicaid and premium subsidies drop by a smaller amount, 10 percent, by 2026. McCain has indicated that he will support the Graham-Cassidy repeal bill.

Murkowski was one of three GOP senators, including McCain, who voted against the "skinny repeal" of ObamaCare in July, killing the bill. The defeat was a major setback for President Trump and Republican leaders in Congress.

The last dissenting GOP lawmaker on the "skinny repeal," Sen. Susan Collins Susan Margaret CollinsMcConnell locks down key GOP votes in Supreme Court fight Most Americans think winner of election should pick next Supreme Court justice: poll Murkowski: Supreme Court nominee should not be taken up before election MORE (R-Maine), hasn't yet stated how she will vote on Graham-Cassidy. According to the CMS study, Maine is set to see a 44 percent increase in federal funding for health care by 2026 under the proposed bill.

Earlier in the week, however, Collins blasted her Republican colleagues for effectively tanking a bipartisan effort to fix ObamaCare by supporting the Graham-Cassidy measure, calling the decision "disappointing."

"It's disappointing that this bipartisan effort — which should be our approach — was not allowed to proceed to conclusion," Collins said Wednesday.

The Senate is expected to vote on the Graham-Cassidy legislation next week. The bill has been called the GOP's "last ditch" attempt to repeal former President Barack Obama Barack Hussein ObamaDemocratic Senate campaign arm outraises GOP by M in August A federal court may have declared immigration arrests unconstitutional Blunt says vote on Trump court nominee different than 2016 because White House, Senate in 'political agreement' MORE's signature health care law.