A man who was holed up in a Launceston house during a 42-hour siege threatened officers with shards of glass when they stormed his property, police allege.

Special Operations Group officers forced their way inside the house on Cedar Street, Newnham, at about 3:00am, more than 40 hours after the stand-off began on Monday.

Commander Brett Smith said the 35-year-old man was significantly violent toward to officers.

"There were no shots fired, there were shards of glass that were produced to the police officers," he said.

"A combination of less-lethal tactical options and force quickly secured him, he has suffered some injuries at which we're evaluating with medical staff."

Police said the man has shoulder injuries and was refusing to have them treated.

He is in custody and is expected to face multiple charges including drugs, family violence and firearm offences.

The man was not holding any firearms when apprehended, police said, and no other firearms were recovered from the house.

On Monday, police recovered a small calibre pistol from the property.

Forensics officers are continuing to search the house for evidence.

Commander Smith said officers entered the house when "opportunity presented", but would not say what that was or what tactics were used.

Siege started after reports of domestic violence

Police converged on the house on Monday morning when the man allegedly took a woman and two children hostage.

A few hours later the woman and children left the house unharmed.

Police recovered a firearm from the property but were unsure if the man was still armed during the ensuing hours.

The police armoured truck, known as a Bearcat, was called in to support Special Operations officers.

Police spoke with the man throughout the ordeal, trying to persuade him to leave the house.

Homes in the street were evacuated but residents living some distance from the man's property were allowed to return.