Physicians between the ages of 40 and 54 experience a higher rate of burnout than older or younger doctors, according to a recent survey of more than 15,000 physicians who cited administrative tasks and work hours as key drivers of their stress.

Nearly half of Generation X physicians who were surveyed said they felt burned out, compared with 39% of baby boomers, ages 55 to 73, and 38% of millennials, ages 25 to 39. Roughly half of all the doctors surveyed also said that they would be willing to take a substantial pay cut to...