The Giants' receiving corps has been further depleted.

Hakeem Nicks will be out of action for three weeks as he is being treated for Compartment Syndrome in his lower right leg, the Giants announced today. Nicks suffered the injury in Sunday night's loss to the Philadelphia Eagles.

The Star-Ledger first reported today that Nicks would miss an undisclosed amount of time with an injury to his leg.

Compartment Syndrome is swelling in the lower leg which compresses nerves and blood vessels and can lead to muscle and nerve damage if not treated immediately.

Nicks is at the Hospital for Special Surgery in New York this afternoon undergoing a fasciotomy to treat the injury, according to the Giants.

Nicks has had a few ankle injuries this season, but nothing so severe that it has knocked him out of action.

Nicks has a team-high 62 catches for 800 yards and nine touchdowns. He had six catches for 65 yards Sunday night against the Eagles.

The loss of Nicks would be the second big blow to Eli Manning's reservoir of targets. Steve Smith is out, likely until early next month, with a partially torn pectoral muscle.