The South Australian Government is hoping a luxury rooftop tent hotel will help keep the old Royal Adelaide Hospital site active during its redevelopment.

The old hospital site will be left empty today as SA Health completes its three-day move of staff and patients to the new hospital.

Urban Development Minister Stephen Mullighan said 14 canvas tents would be placed on the old hospital rooftop and helipad later in the year.

Mr Mullighan said the tent hotel would be run by a Victorian group which charges more than $400 a night for the experience in Melbourne.

"It's been extremely successful in the high-rise buildings of the Melbourne CBD and it's something we're bringing to Adelaide," Mr Mullighan said.

"We want people experiencing particularly some of the old beautiful heritage buildings, and also keeping people around that part of the city to continue providing a boost to the East End."

Mr Mullighan also promised to reveal more details in the coming days about the overall plan to redevelop the site.

The Government previously announced about a third of the hospital site would be returned to the Botanic Gardens, with developers set to transform the remaining heritage buildings into a research and cultural precinct.

The site will also house new multi-storey apartment buildings.

It could take four years and cost $150 million to demolish several buildings at the old hospital.