Two soldiers of the Military Emergency Unit are seen carrying material to disinfect the nursing and day centre ORPEA Sanchinarro for the second time to stop coronavirus infection on April 01, 2020 in Madrid, Spain. Europa Press News

The coverage on this live blog has ended — but for up-to-the-minute coverage on the coronavirus, visit the live blog from CNBC's U.S. team. Global cases: More than 856,900

Global deaths: At least 42,081

Top 5 countries: United States (187,919), Italy (105,792), Spain (95,923), China (82,278), and Germany (71,808) The data above was compiled by Johns Hopkins University as of 7:58 a.m. Beijing time. All times below are in Beijing time.

7:13 pm: Putin to hold meeting by video-conference after contact with coronavirus doctor, Kremlin says

Russian President Vladimir Putin will hold a government meeting on Wednesday by video conference, the Kremlin said, Reuters reported. It comes a day after a doctor who met Putin last week said he had been diagnosed with the virus. Denis Protsenko last week gave Putin a tour of Moscow's main coronavirus hospital and shook hands with the Russian leader. Protsenko is now self-isolating in his office. The Kremlin, which has said that everything is fine with Putin's health, said on Wednesday he was keeping his distance from other people and preferred to work remotely. — Holly Ellyatt

6:36 pm: Spain now has more than 100,000 cases, record daily death toll

Spain now has 102,136 coronavirus cases, its health ministry reported Wednesday, with the number of fatalities over the last 24 hours reaching a record 864 people. A total number of 9,053 people have now died from the disease in Spain. The total number of cases rose by 7,719 from Tuesday. — Holly Ellyatt Tweet

6:00 pm: UK urges hospitals to increase testing for coronavirus

The U.K.'s health minister has asked hospitals to use spare laboratory space to test frontline and self-isolating NHS staff for coronavirus, amid concerns of a lack of testing for health care workers, and potentially unnecessary staff absences. Health Secretary Matt Hancock called for more testing of health service workers as pressure grows on the government over its small amount of testing compared to other countries, like Germany. Another government minister, Michael Gove, said the U.K. had to go "further, faster" to increase testing. — Holly Ellyatt

5:03 pm: Indonesia set to open emergency coronavirus hospital on uninhabited island

Indonesia will by next week open a new coronavirus emergency hospital on the uninhabited island of Galang, Reuters reported Wednesday. The authorities there have reportedly re-purposed a former Vietnam war era refugee camp as part of efforts to rapidly augment health care capacities. Indonesia has recorded 1,677 cases of coronavirus as of April 1, and 157 deaths - the highest mortality rate in Southeast Asia. It's believed the infection rate among Indonesia's population of 260 million could be substantially higher, while official data from mid-March shows the country has only about 12 hospital beds per 10,000 people. — Holly Ellyatt

Workers using heavy equipment lift medical equipment to be used for Corona Special Hospital (COVID-19) at Hang Nadim Airport in Batam, Riau Islands, , on March 12, 2020.. A number of medical devices for the Corona Special Hospital on Galang Island which were transported by the TNI Air Force Squadron 31 type A-1317 Halim Perdanakusuma. NurPhoto

4:30 pm: US, Italy and Spain have the most coronavirus cases. These charts show their infection curves

The ongoing coronavirus pandemic has shown few signs of abating and is now one of the largest threats to the global economy and financial markets. The virus, first reported in the Chinese city of Wuhan in December, has spread to 180 countries and territories, according to data compiled by Johns Hopkins University. Globally, more than 850,000 infections have been reported, with over 42,000 deaths, the data showed. Take a look at these seven charts that show how the coronavirus disease, which has been formally named COVID-19, has spread in countries with the largest outbreaks. — Yen Nee Lee and Audrey Cher

4:08 pm: Italy's manufacturing activity fell to a 131-month low in March

Italy's manufacturing sector saw activity fall to its lowest level in nearly 11 years in March, purchasing managers' index (PMI) data from IHS Markit showed Wednesday. Italy saw the sharpest deterioration in operating conditions, IHS Markit said, with the manufacturing PMI falling to 40.3. The euro zone's manufacturing PMI for March came in at 44.5, below an initial reading of 44.8. Elsewhere, France, Ireland and Spain all saw multiyear low readings for their PMIs. Only the Netherlands recorded a PMI above the 50.0 level in March, though growth there was marginal. The 50-point mark separates expansion from contraction. — Holly Ellyatt

3:15 pm: Forecast of 6% fall in Italy's GDP in 2020 is 'realistic,' economy minister says

Italy's Economy Minister Roberto Gualtieri said on Wednesday that a forecast of a 6% fall in gross domestic product due to the coronavirus emergency this year is realistic. The forecast was made by Italian business lobby Confindustria. "Unfortunately the estimates are realistic ... at the same time we can aim for a vigorous recovery," Gualtieri told newspaper Il Fatto Quotidiano in an interview published Wednesday. "The more rigorous and effective we are in tackling the epidemic, the sooner we can start again. The economic measures that we are taking to avoid layoffs, support income and provide all the liquidity necessary to avoid a reduction in production capacity are all necessary," he said. — Holly Ellyatt

2:20 pm: Macao's gaming revenue plunge 80% in March

Gaming revenue in Macao dived 79.7% in March year-on-year as the flow of tourists dried up due to the pandemic, Reuters reported, citing the Chinese territory's government. It said that major operators Wynn Macau, Sands China, MGM China, Galaxy Entertainment were all losing between $1.5 million and $4 million a day to keep operations going. Last week, Macao banned visitors from mainland China, Hong Kong and Taiwan who have traveled overseas, following an earlier ban on foreign visitors. — Weizhen Tan

1:30 pm: China reports 36 new cases, 7 deaths

China's National Health Commission (NHC) reported 36 new cases as of March 31, of which 35 were "imported." It had seven more deaths, of which 6 were in Hubei, the epicenter of the outbreak. That brings China's total to 81,554 confirmed cases and 3,312 deaths, the NHC said. Starting Wednesday, the NHC will report data on asymptomatic cases under medical observation. There were 130 new asymptomatic cases as of March 31, with a total of 1,367 under this observation, according to the NHC. — Weizhen Tan, Christine Wang

12:20 pm: Investors can do some buying as markets are 'a lot cheaper,' says billionaire investor Howard Marks

Oaktree Capital co-chairman Howard Marks is leaning toward a more negative outlook because of the uncertainty from the coronavirus pandemic, but still, he said investors can do some buying as "things have gotten cheap enough." He urged investors to take a moderate approach in these uncertain times, adding that his approach "is not black or white, buy or sell." "I never believe that I know when's the bottom, but I know things have gotten a lot cheaper and it's reasonable to do some buying. If it goes lower, do more buying," Marks told CNBC's Tanvir Gill. — Weizhen Tan

11:23 am: Nissan suspends production at Kyushu plant after employee tests positive

Nissan Motor said it stopped operating the vehicle production line at its Kyushu plant to begin disinfection work after an employee there tested positive for COVID-19 on March 31. It did not give an indication of when operations may resume, saying that it would be decided based on the guidance of health authorities. Last week, the automaker said it would temporarily adjust production at three of its manufacturing facilities in Japan due to decreased demand in the automobile market. — Saheli Roy Choudhury

11:05 am: A private survey shows China's manufacturing activity expanded slightly in March

Business confidence in China improved as output resumed gradually after lockdowns were lifted, a private survey showed. The Caixin/Markit manufacturing Purchasing Manager's Index for March was 50.1. Analysts polled by Reuters had expected the Caixin/Markit PMI to come in at 45.5, compared with February's sharpest contraction on record at 40.3. PMI readings above 50 indicate expansion, while those below that level signal contraction. Caixin and IHS Markit noted demand challenges ahead. The Chinese government implemented large-scale lockdowns and quarantines of millions of people since late January to contain the outbreak of the coronavirus disease, formally known as COVID-19. This restricted movement and economic activity. — Huileng Tan

11 am: Japanese carmakers brace for US sales shock as coronavirus hits consumers

As the U.S. auto industry braces for the biggest downturn since the 2008 financial crisis, analysts are counting the cost for Japan's automakers — whose fortunes depend heavily on the world's second-largest car market. To reﬂect weaker U.S. demand, Goldman Sachs slashed its combined operating proﬁt estimate for seven Japanese automakers by 22% in a note to clients last week. Nissan is projected to fare the worst under Goldman's revision, with fiscal year 2021 operating proﬁt forecast cut by 92%.— Nancy Hungerford

10:30 am: South Korea reports 101 new cases, three additional deaths

Another 101 people in South Korea were confirmed to have the coronavirus, bringing the country's total number of infections to 9,887, according to the latest numbers from the Korea Centers for Disease Control and Prevention. Three more people died from the virus; the total death toll in the country stands at 165. Though the infection rate in South Korea has relatively slowed down compared to what it was at its peak in late February, new reported daily cases are still hovering near or above 100.

As part of the measures to contain the spread of infection, South Korea made it mandatory for all new arrivals to the country to be placed in self-quarantine for 14 days starting Wednesday, Yonhap reported. Those who do not have a place of residence in the country will be charged around 100,000 Korean won ($82) a day for using public facilities, according to the news agency. — Saheli Roy Choudhury

9:36 am: HSBC, StanChart shares fall in Hong Kong

9:15 am: Los Angeles encourages residents to report non-essential businesses violating stay-at-home orders

Los Angeles Mayor Eric Garcetti asked Los Angeles residents to report businesses violating the city's order to stay at home and said that recurring violations could be submitted to a new city website. 144 businesses in Los Angeles have been visited by the LAPD in relation to violations of the order, according to the mayor. Washington state earlier released a web form on Monday to speed up the process of reporting businesses violating that state's stay home order. "You know the old expression about snitches, well, in this case, snitches get rewards. We want to thank you for turning folks in and making sure we are all safe," Garcetti said. — Kif Leswing

8:50 am: Japan's large manufacturers are pessimistic about business conditions

The Bank of Japan's "Tankan" survey showed Japanese manufacturers are pessimistic about business conditions in the country. The closely-watched sentiment index among large manufacturers fell to negative 8 in the three months that ended on March 31 from zero in the October-December quarter; a negative reading implies most of them see business conditions to be unfavorable. It underscored the challenges Prime Minister Shinzo Abe faces as he attempts to navigate Japan's economy through the global impact of the coronavirus pandemic. Sentiment also worsened among medium and small manufacturing companies as well as the non-manufacturing firms.

Snow falls as people wearing face masks walk through the Asakusa district on March 29, 2020 in Tokyo, Japan. Tomohiro Ohsumi | Getty Images

The indexes are calculated by subtracting the percentage of businesses which said they find conditions unfavorable from those that said they find it favorable. The survey is often an indicator of Japan's economic health and factors into the central bank's considerations for monetary policy implementation. — Saheli Roy Choudhury

7:46 am: Korean Air reportedly to suspend flights to Washington DC

Korean Air will suspend flights to Washington D.C. starting April 13 through to the end of May, Reuters reported. The airline cited the coronavirus as a reason and a spokesperson said passenger demand for air travel to the U.S. fell sharply due to the rapid spread of the virus there, Reuters said. Korean Air has already suspended or reduced routes between Incheon and a number of U.S. cities including Los Angeles, New York, and Seattle. — Saheli Roy Choudhury

7:39 am: Global coronavirus death toll over 42,000

The fast-spreading coronavirus, which causes the disease COVID-19, has killed at least 42,081 people around the world since it was first reported in China's Hubei province late last year, according to data compiled by Johns Hopkins University. Most of the deaths occurred in Europe: 12,428 people have died in Italy, 8,464 in Spain and 3,523 in France. China has recorded 3,309 deaths to-date, though some have raised questions about the accuracy of the reported numbers there.

There are at least 856,955 cases of infection worldwide, with more than 187,919 infected in the United States alone. About 177,917 people have recovered from the disease, most of them in China, followed by Spain, Germany, Italy, and Iran. — Saheli Roy Choudhury All times below are in Eastern time.

6:51 pm: Senators push Mnuchin to guarantee oversight of $500 billion bailout fund

Leading Democratic senators called on Treasury Secretary Steven Mnuchin to ensure proper oversight of a $500 billion fund aimed at helping companies hit by the coronavirus' economic fallout. The fund, which was established as part of a more than $2 trillion stimulus bill President Donald Trump signed into law last week, became a point of contention for Democrats who worried that earlier versions of the bill gave Mnuchin too much discretion over how the funds are dispersed. After tense negotiations, Republicans and Mnuchin agreed to add an inspector general to oversee that fund, as well as a congressional committee. But Trump on Friday questioned the authority of the inspector general. According to a signing statement he released alongside the bill, he declared his belief that the inspector general needs his permission before letting Congress know whether Mnuchin or Treasury block efforts to glean information. — Lauren Hirsch

5:56 pm: White House predicts 100,000 to 240,000 will die in US from coronavirus

President Donald Trump prepared Americans for a coming surge in coronavirus cases, calling COVID-19 a plague and saying the U.S. is facing a "very, very painful two weeks." "This is going to be a rough two-week period," Trump said at a White House press conference. White House officials are projecting between 100,000 and 240,000 deaths in the U.S. with fatalities peaking over the next two weeks. "When you look at night, the kind of death that has been caused by this invisible enemy, it's incredible." — Berkeley Lovelace Jr.

5:36 pm: CDC says diabetes, lung disease, heart disease and smoking may increase risk of severe coronavirus illness