Just days after John McCain had a blood clot removed above his left eye, late on Wednesday his office announced that McCain has a brain tumor associated with the removed blood clot. In a statement doctors revealed that McCain has been diagnosed with glioblastoma, an aggressive cancer. The statement says the 80-year-old senator and his family are reviewing further treatment, including a combination of chemotherapy and radiation.

The tumor was revealed after surgery to remove blood clot, with the statement noting that "scanning done since the procedure (a minimally invasive craniotomy with an eyebrow incision) shows that the tissue of concern was completely resected by imaging criteria."

Doctors say that "the Senator's doctors say he is recovering from his surgery 'amazingly well' and his underlying health is excellent."

Full statement below:

STATEMENT FROM THE OFFICE OF SENATOR JOHN McCAIN "On Friday, July 14, Sen. John McCain underwent a procedure to remove a blood clot from above his left eye at Mayo Clinic Hospital in Phoenix. Subsequent tissue pathology revealed that a primary brain tumor known as a glioblastoma was associated with the blood clot. "Scanning done since the procedure (a minimally invasive craniotomy with an eyebrow incision) shows that the tissue of concern was completely resected by imaging criteria. "The Senator and his family are reviewing further treatment options with his Mayo Clinic care team. Treatment options may include a combination of chemotherapy and radiation. "The Senator's doctors say he is recovering from his surgery 'amazingly well' and his underlying health is excellent." The office of Senator John McCain also released the following statement: "Senator McCain appreciates the outpouring of support he has received over the last few days. He is in good spirits as he continues to recover at home with his family in Arizona. He is grateful to the doctors and staff at Mayo Clinic for their outstanding care, and is confident that any future treatment will be effective. Further consultations with Senator McCain's Mayo Clinic care team will indicate when he will return to the United States Senate."

McCain has previously overcome cancer. He revealed in 2008 during his presidential campaign that he had four malignant melanomas removed in surgeries in 1993, 2000 and 2002.

His daughter, Meghan McCain, she said that "the news of my father's illness has affected every one of us in the McCain family. My grandmother, mother, brothers, sister and I have all endured the shock of the news and now we live with the anxiety about what comes next."

Mitch McConnell also commented on the diagnosis, saying that McCain "never shied from a fight…he will face this challenge with the same extraordinary courage that has characterized his life"

McConnell: McCain "never shied from a fight…he will face this challenge with the same extraordinary courage that has characterized his life" pic.twitter.com/CndqEiy60j — Bradd Jaffy (@BraddJaffy) July 20, 2017

And former President Obama said "McCain was as tough as they come."

John McCain is an American hero & one of the bravest fighters I've ever known. Cancer doesn't know what it's up against. Give it hell, John. — Barack Obama (@BarackObama) July 20, 2017

Finally President Trump issued a statement: Senator John McCain has always been a fighter. Melania and I send our thoughts and prayers to Senator McCain, Cindy, and their entire family. Get well soon.