WASHINGTON — The Trump administration announced on Monday that it was broadening sanctions against Venezuela, blacklisting four government officials and banning a digital currency President Nicolás Maduro created last month to circumvent financial sanctions on his economically strapped nation.

The White House said the new measures were intended to send a message to Mr. Maduro’s government, which it has accused of corruption and repression, that the United States remains focused on the economic devastation in Venezuela, and holds the president and his associates directly responsible for creating the conditions there. The nation is in the throes of food and medicine shortages and a collapse of the health system as well as other government services, circumstances that have prompted hundreds of thousands of Venezuelans to flee.

The intensification of sanctions comes as President Trump prepares to attend the Summit of the Americas next month in Lima, Peru, where the crisis in Venezuela will be a central issue. Vice President Mike Pence is scheduled to deliver a speech this week at the Organization of American States in Washington, where he plans to call out “the Maduro regime’s lawless actions,” according to a spokeswoman, and urge swift action to address the humanitarian situation and restore political order.

The sanctions also come just two months before Mr. Maduro is to stand for re-election in a race he is expected to win given his control of Venezuela’s political and judicial machinery. The United States is among the countries that have declared they will not recognize the results.