For the second time in a week, a beer truck crash has closed a major highway.

On Saturday the southbound lanes of Interstate 25 were closed for several hours at Colorado 66 when a beer truck overturned south of Mead. The highway reopened a little before 7 p.m., the Colorado Department of Transportation said. The accident happened just after noon.

upd:SB I-25 closed @ CO-66 b/c an accident S of Mead;no est time of reopening;All SB traffic must exit @ CO-66 — CDOT (@ColoradoDOT) July 23, 2016

Denver7 reported that AirTracker7 flew over the scene as crews were working to free the driver, whose condition is unknown at this time. A Colorado State Patrol spokesman said she had little information about the crash or injuries, but said people had been transported to the hospital.

On Wednesday, a tractor-trailer hauling beer crashed on the ramp from eastbound Interstate 70 to northbound Interstate 25, causing delays.

Denver police said there were no injuries in that crash.

The Longmont Times-Call and Denver7 contributed information for this report.