SOUTH REGION (Louisville, Ky.)

No. 1 Virginia (31-3) vs. No. 12 Oregon (25-12)

After defeating its demons and No. 16 Gardner-Webb (along with No. 9 Oklahoma), the Cavaliers have the privilege of facing the sole double-digit seed left in the field. Oregon is one of college basketball’s hottest teams, riding a 10-game win streak. But if Virginia plays to its seed — admittedly an issue over the last several years — then it should have little problem dispatching an inferior Ducks squad.

Line: Virginia -8 (William Hill)

No. 2 Tennessee (31-5) vs. No. 3 Purdue (25-9)

This may not read as the sexiest matchup of the regional semifinals, but it is likely the best. These are two excellent, veteran teams with chips on their shoulders (both programs see themselves as historically disrespected, and neither won its conference tournament). Both have good coaches, and deep reserves of talent. The Volunteers might be favored, but when Purdue gets good minutes out of the 7-foot-3 sophomore Matt Haarms — as it did Saturday, when it blew out the defending champion, Villanova — the Boilermakers look as good as anyone in the country. Expect fans to pour into Kentucky from the north and the south.

Line: Tennessee -1 (William Hill)