Noah Israel Chamberlin was reported missing on Thursday afternoon after he disappeared during a walk in the woods behind his Tennessee home

A desperate search continues for a missing two-year-old boy who disappeared while on a walk in the woods behind his Tennessee home with his grandmother, authorities said.

Noah Israel Chamberlin was reported missing at 1.19pm on Thursday after his grandmother had taken him and his sister on a nature hike when she said she lost sight of him.

Search crews canvassed the woods surrounding the toddler's Pinson home on Thursday night into the early hours on Friday as they looked for the boy, according to The Jackson Sun.

Madison County Sheriff's Office spokesman Tom Mapes said Noah, his grandmother and four-year-old sister sat down to talk while in the woods and when the grandmother turned around, he was gone.

'They sat down to talk and she was paying attention to the granddaughter, and when she turned around he was gone,' Mapes said. 'She immediately went to look for him.'

Authorities said his disappearance is not considered suspicious, according to The Jackson Sun.

Search crews canvassed the woods surrounding the toddler's Pinson home on Thursday night and into the early hours on Friday. Authorities said his disappearance is not considered suspicious

Mapes said additional search teams on foot would re-enter the woods with crews on four-wheelers as they search side-by-side through the area beginning where Noah was last seen.

He also said the search area is about 600 acres and that the woods surrounding the boy's home is filled with creeks and rough terrain.

So far more than 100 people have been involved in the search which has included helicopters and K-9 units.

Authorities said they are concerned about colder temperatures and early morning rain, according to The Jackson Sun.

According to an endangered missing child alert for Noah, he is described as a white male with blonde hair and blue eyes who stands two feet tall and weighs 25 pounds.

Noah was last seen wearing a long-sleeved gray shirt and blue jeans.