For various number of diseases, tests are performed for the advancement in microchip technology that enables doctors or staff members to shift specific molecules in early stage of cancer cells that varies from even single drop of blood. But the fabrication of lab-on-a-chip enable the designing of integrated and small diagnostic senor arrays on the surfaces that is as small as a square centimeter by Top Engineering College in Jaipur. It is considered as technically challenging task that consumes large amount of time and expensive feat.

For this, very precise, small and reproducible techniques have been introduced that reduce the time and the cost of fabrication of such sensors. Also, an engraving technique have been developed that mark small and Nano-sized patterns on metallic surfaces that further uses small stamp that are activated with voltage and are made out of the glass. It is made up of tiny dots that are much smaller in width with one-hundredth of human hair. It can act as optical antennae that help in the identification of a single molecule by picking specific and particular wavelength. The creation of these optical antennae with precise or less dimensions helps in reporting traffic on the molecular scale.

The approach used in the making of new glass stamp by the List of Engineering Colleges in Rajasthan that help most of the researcher in clearing large hurdle in a lab on special kind of chip that is named as scale-up. At today’s time, Nano-sensors are fabricated with the usage of electron-beam lithography which is considered as the most time-consuming and expensive technique which further uses focused beam of electrons that slowly inserts pattern into different metallic surfaces.

The use of expensive technology leads to some more introductions that are cheaper like Nano-imprint lithography. This process is very simple and low in cost where a moldable polymer can be pressed easily onto the main circuit pattern. When it is exposed to ultra-violet lights, the polymer will become harder and when the master circuit is peeled off, there will be the formation of mold that can be filled with a metal substrate for making a copy of original circuit pattern. At the time of experiments, there are scientists that typically wash the polymer for the isolation of new metallic pattern.