2004 The AHA and ILCOR release a statement about AED use in children, stating that for children ages 1 year to 8 years who have no signs of circulation, it is appropriate to use an AED.

2005 The AHA develops the Family & Friends® CPR Anytime® kit, an innovative product that enables anyone to learn the core skills of CPR in just 20 minutes. The kit provides everything needed to learn basic CPR, AED skills, and choking relief anywhere, from a family room at home to a setting for instructing large groups. The 2005 International Consensus on CPR and ECC Science With Treatment Recommendations (CoSTR) Conference leads to the AHA publishing the 2005 AHA Guidelines for CPR and ECC. The Guidelines recommend a new compression-to-ventilation ratio of 30:2 as well as changes to AED usage.

2008 The AHA releases new recommendations that say bystanders can skip mouth-to-mouth resuscitation and use Hands-Only CPR to help an adult who suddenly collapses.20 In Hands-Only CPR, bystanders dial 9-1-1 and provide high-quality chest compressions by pushing hard and fast in the center of the victim’s chest.

2010 After the 2010 International CoSTR Conference, the AHA publishes the 2010 AHA Guidelines for CPR and ECC. 2010 also marks the 50th anniversary of CPR.

2012: Hands-Only CPR Hits the Road to Save Lives The AHA's Hands-Only Mobile Tour hits the road to teach Hands-Only CPR across the country. AHA's Hands-Only CPR mobile tour visits southern Maine.

2013 The AHA installs an interactive CPR kiosk at Dallas-Ft. Worth airport. It features a practice manikin, video, and touch screen that give performance feedback as passengers between flights learn to perform hands-only CPR. Within 5 years, there will be more than 30 CPR kiosks in cities across the country.

2015 The Institute of Medicine releases its report Strategies to Improve Cardiac Arrest Survival: A Time to Act (2015). After the 2015 International CoSTR Conference, the AHA publishes the 2015 AHA Guidelines Update for CPR and ECC.

2017 The AHA begins its continuous evidence evaluation process for the Guidelines for CPR and ECC and, later that year, releases the 2017 Focused Update.