DETROIT — When the Yankees open their next homestand, they should finally have some familiar faces back.

Luis Severino is expected to start Tuesday against the Angels, which would be his first start of the season. And Giancarlo Stanton could be in the lineup.

Severino came through his second rehab outing with Double-A Trenton fine, and manager Aaron Boone said Thursday that Severino’s next start would be in the Bronx.

“We’re excited to get him back,” Boone said of Severino, who will meet the team this weekend in Toronto after throwing 64 pitches on Wednesday.

The right-hander has been out the entire season after suffering right shoulder inflammation and then a strained lat while rehabbing his shoulder. The two injuries followed the four-year, $40 million contract extension he signed this spring.

“I’ve been talking awhile that he’s been in a pretty good place physically now for a couple months, building good momentum and his progression has gone really smooth,” Boone said.

Severino could make three starts with the Yankees before the end of the regular season.

“Hopefully that allows him to continue to build up and find that consistency,” Boone said. “He could be a game-changer guy for us, no question.”

How he fits into the Yankees’ postseason rotation remains to be seen. Boone said “everything is on the table” in terms of how they might use their pitchers in the playoffs.

“We have a lot of confidence in our entire staff, from our bullpen to the starters,” Boone said. “How we do it [in the playoffs] will probably be a fluid situation and depend on what teams we’re playing and what the matchups are. I would say anything, at this point, is possible.”

That could involve using starters in a traditional way or going with multiple starters in one game, as the Yankees were slated to do in the first game of Thursday’s doubleheader against the Tigers. CC Sabathia is starting and Domingo German is scheduled to follow.

Dellin Betances will likely make another rehab appearance for Trenton on Friday, and his season debut with the Yankees shouldn’t be far off, either. Boone believes the right-hander has enough time to pitch on back-to-back days before the postseason.

And when Severino pitches on Tuesday, Stanton could be active, as well.

“There’s a good chance of that,” Boone said.

Stanton might play in instructional games in Tampa this weekend, and the Yankees hope to get him healthy enough to be an option in the outfield.

He’s played just nine games this season, sidelined by a torn biceps, a left shoulder injury and then a sprained right knee that has kept him out since June 25.

“We hope everything goes well and he’ll be an option for us when we get home,” Boone said. “We want to make sure he’s good, ready to go and can do everything and is as close to 100 percent as we can get him.”