Cairo (CNN) At least 25 people were killed and 40 others injured Wednesday morning in a fire at Egypt's busiest railway station, the country's health ministry said, according to state media.

The Ramses station in central Cairo was set ablaze after a train collided with the platform and its fuel tank exploded, state-run news site Al-Ahram reported, citing security sources.

The deadly incident prompted Egypt's Transportation Minister Hisham Arafat to resign, according to Al-Ahram.

Egypt's Health Minister, Hala Zayed, told reporters in a televised press conference that many of the injured are in a critical condition, with second- and third-degree burns. Thirty ambulances were on site, but people in the area volunteered to take some of the injured to the hospital in their own cars.

Egypt's Prosecutor General, Nabil Sadek, has ordered an investigation, according to Al-Ahram. President Abdel Fattah el-Sisi has also vowed to bring those responsible for the accident to justice.

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