Introduction Suicide rates among middle-aged men and women in the U.S. have been increasing since 1999, with a sharp escalation since 2007.

Purpose To examine whether suicides with circumstances related to economic crises increased disproportionately among the middle-aged between 2005 and 2010.

Methods This study used the National Violent Death Reporting System (NVDRS) in 2014 to explore trends and patterns in circumstance and method among adults aged 40–64 years.

Results Suicide circumstances varied considerably by age, with those related to job, financial, and legal problems most common among individuals aged 40–64 years. Between 2005 and 2010, the proportion of suicides where these circumstances were present increased among this age group, from 32.9% to 37.5% of completed suicides (p<0.05). Further, suffocation is a method more likely to be used in suicides related to job, economic, or legal factors, and its use increased disproportionately among the middle-aged. The number of suicides using suffocation increased 59.5% among those aged 40–64 years between 2005 and 2010, compared with 18.0% for those aged 15–39 years and 27.2% for those aged >65 years (p<0.05).