Former Minnesota Gov. Tim Pawlenty (R) ruled out running for the Senate seat vacated by Sen. Al Franken Alan (Al) Stuart FrankenGOP Senate candidate says Trump, Republicans will surprise in Minnesota Peterson faces fight of his career in deep-red Minnesota district Getting tight — the psychology of cancel culture MORE (D-Minn.), depriving Republicans of a strong candidate in an unexpected pickup opportunity on the midterm map.

“I am very interested in public service and service for the common good. There are a lot of ways to do that,” Pawlenty said in an interview with Fox Business Network.

“But I’ll tell you today that running for the United States Senate in 2018 won’t be part of those plans.”

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Pawlenty had been floated as a potential candidate to run for the seat, given that's he's won election in Minnesota before as a statewide candidate. Pawlenty didn’t run for a third term as governor in 2010 and instead unsuccessfully ran for president in 2012.

He also has strong ties to GOP donors and the national party.

His decision not to run for the Senate seat following Franken’s resignation after multiple sexual misconduct allegations is another bad sign for Republicans going into what looks like a difficult midterm election.

Two incumbent House Republicans announced their retirements last week in a sign that both thought they might lose reelection.

Separately, Rep. Kevin Cramer Kevin John CramerOn Paycheck Protection Program, streamlined forgiveness is key McConnell shores up GOP support for coronavirus package Army Corps urges DOJ to settle case with ND over M DAPL damages MORE (R-N.D.) decided not to take on Sen. Heidi Heitkamp Mary (Heidi) Kathryn HeitkampCentrists, progressives rally around Harris pick for VP 70 former senators propose bipartisan caucus for incumbents Susan Collins set to play pivotal role in impeachment drama MORE (D-N.D.), who on paper looks like a vulnerable candidate in the midterms given that President Trump Donald John TrumpObama calls on Senate not to fill Ginsburg's vacancy until after election Planned Parenthood: 'The fate of our rights' depends on Ginsburg replacement Progressive group to spend M in ad campaign on Supreme Court vacancy MORE coasted to victory in North Dakota.

In explaining his decision, Pawlenty said he would only have had less than a year to mount a campaign in a “tough” state for Republicans. No Republican candidate has won statewide in Minnesota since 2006, though Trump came close to winning the state in the 2016 presidential race.

“I certainly appreciate that kind of encouragement and people thinking of me in those terms. But if anybody’s going to run for United States Senate this November, that’s now only 10 months away and it’s going to a be a very competitive race and tough state for Republicans,” Pawlenty said.

Minnesota Lt. Gov. Tina Smith Tina Flint SmithThe Hill's Campaign Report: Trump and Biden vie for Minnesota | Early voting begins in four states | Blue state GOP governors back Susan Collins GOP Senate candidate says Trump, Republicans will surprise in Minnesota Biden promises Democratic senators help in battleground states MORE (D) was appointed to fill the seat until the November elections and she’s also running to fill out the remainder of Franken’s term which expires in 2020.

Franken’s seat isn’t the only Senate seat that Minnesota Democrats will need to defend. Sen. Amy Klobuchar Amy KlobucharThe Hill's Morning Report - Sponsored by The Air Line Pilots Association - White House moves closer to Pelosi on virus relief bill EPA delivers win for ethanol industry angered by waivers to refiners It's time for newspapers to stop endorsing presidential candidates MORE (D-Minn.), who has been floated as a potential presidential contender, is up for reelection in 2018, though she’s expected to easily hold onto her seat.

Senate Democrats will mostly be on defense this cycle, with 10 incumbents up for reelection in states where Trump won in 2016. Franken’s resignation gave Republicans a glimmer of hope that they could flip a seat in Minnesota.

Other Minnesota Republicans have indicated some interest in the race, though Pawlenty would have likely been the party’s best shot at the open-seat race.

Former Rep. Michele Bachmann Michele Marie BachmannEvangelicals shouldn't be defending Trump in tiff over editorial Mellman: The 'lane theory' is the wrong lane to be in White House backs Stephen Miller amid white nationalist allegations MORE (R-Minn.) said in early January that she’s considering a Senate run.