ASUS Prime B350M-E

A uATX motherboard powered by AMD B350 chipset that works flawlessly with AMD Ryzen and 7th generation A-series Athlon processors in AM4 packaging. It supports dual-channel DDR4 up to 3200(O.C.), and features a M.2 connector (SATA & PCIE 3.0 x 4 mode) for maximized storage speed. 5X Protection III Hardware-level safeguards provide component with longevity and reliability, and the PCIe slot is reinforced with metal framing for heavyweight GPUs. Plus, 8-channel HD audio driven by Japanese capacitors brings studio-class sound for your games, movies and music, right to your desktop PC.

ASUS Prime is the next evolution of the ASUS motherboard, born of a pedigree that stretches back to 1989. ASUS’ team of world-class engineers are passionate about empowering everyone to enjoy the benefits of customization and tuning, and the driving force behind the development of Prime is to make advanced enthusiast controls easily accessible - maximizing performance, stability and compatibility for the very best DIY PC experiences. Simply stated: it's time for Prime.

Reliable Stability and Compatibility

Built to Last

ASUS is the world's foremost motherboard manufacturer, renowned for their unique Design Thinking approach. Their exhaustive testing exceeds industry standards, supported by high-quality components for exceptional real-world protection. Asus motherboards are proven to be compatible with more than 1,000 components and devices, and each new model undergoes a minimum of 8,000 hours of strict validation. ASUS gives you the peace of mind of knowing that your motherboard is fit for all environments and applications. By choosing ASUS, you also gain the freedom to select outstanding component options, for trouble-free DIY experiences.

5X Protection III

Hardware safeguards to ensure long-term durability. 350+ DDR4 Compatibility

Industry-leading DDR4 memory compatibility for the best flexibility and reassurance. 1000+ Compatible Devices

Compatibility with a range of CPUs, memory modules, graphics cards and more. 8000+ Validation Hours

Extensive testing with latest components for enhanced reliability, compatibility and safety.

PRIME B350 series motherboards are engineered with industry-leading 5X Protection III, employing the finest components, excellent circuit design, and exacting standards to guarantee the quality and long-term durability of your motherboard. That means exceptional protection and stability for your build — thanks to decades of engineering experience from the world's leading motherboard brand.

ASUS SafeSlot

Protect your graphics card investment

SafeSlot is the PCIe slot reinvented by ASUS and engineered to provide superior retention and shearing resistance. Manufactured in a single step using a new insert-molding process to integrate the slot with fortifying metal support for an inherently stronger design, SafeSlot is then firmly anchored to the motherboard through additional solder points.

LANGuard

Pumped-up throughput. 2.5x higher surge tolerance.

ASUS LANGuard is hardware-level networking protection that employs signal-coupling technology and premium anti-EMI surface-mounted capacitors to ensure a more reliable connection and better throughput, plus electrostatically guarded and surge-protected components for greater tolerance to static electricity and improved protection against surges.

* ESD result is undertaken by individual LANGaurd

Overvoltage Protection World-class circuit-protecting power design An exclusive circuit design with built-in voltage regulators to protect your chipset, connectivity ports, and audio codecs from damage caused by unexpected high-level voltages from unstable or inferior power supplies. * Specifications and features vary by model, and all images are illustrative. Please refer specification pages for full details.

DIGI+ VRM

Precision control for stable power



ASUS-exclusive DIGI+ VRM intelligently delivers power to the processor based on real-time demands, reducing energy waste and improving system stability. DRAM Overcurrent Protection

Short-circuit damage prevention



Onboard resettable fuses prevent overcurrent and short-circuit damage. This extends beyond I/O ports to DRAM to safeguard the lifespan of your system and connected devices. Stainless-Steel Back I/O

3x corrosion-resistance for greater durability



Corrosion-resistant stainless-steel back I/O panels bonded with chromium oxide have a lifespan that's three times longer than ordinary panels.

ESD Guards

Electrostatic discharge protection

ASUS ESD Guards prevent damage from electrostatic discharge, up to +/- 10kV for air discharge and +/- 6kV for contact discharge, arranged in an active-protective-circuit design that prolongs the life of components.

* Specifications and features vary by model, and all images are illustrative. Please refer specification pages for full details.

Proven Compatibility

Tested to be compatible with 1,000+ CPUs, DDR4 memory modules, graphics cards and more

Having the freedom to pick and choose the parts that go into your machine is at the heart of PC DIY. Asus’ extensive certification program focuses on providing the very best compatibility with the widest range of components and devices, giving you the freedom to build and upgrade without frustration. Compatible today and compatible far into the future - that's the ASUS way.

Extensive List of Supported Devices View supported devices and Qualified Vendor List for compatible memory The superior compatibility of Prime B350 series is evidenced by Asus’ extensive list of supported devices - which includes thousands of compatible components - and Asus’ Qualified Vendor List that identifies memory compatibility. That means more choices for worry-free PC-building experiences.

Great Compatibility with ASUS Products

ASUS offers a suite of proprietary components — graphics cards, sound cards, optical drives — that perfectly complement Prime B350 series, so you can complete your custom motherboard build with confidence!

* Specifications and features vary by model, and all images are illustrative. Please refer specification pages for full details.

Top-to-bottom Reliability

ASUS motherboards have superb endurance. ASUS verify this by subjecting every board to more than 8,000 hours of stringent tests. A barrage of burn-in, environmental, compatibility, software and safety tests confirm that ASUS’ motherboards are exceptionally robust. It also shows that ASUS reliability surpasses industry standards, ensuring that every component is designed to function flawlessly in any environment.

Temperature and Humidity Test

Ensures components withstand extreme conditions. Thermal Measurement Test

Ensures that the system remains cool and stable under the heaviest loads. Insertion Test

Every port and connector is put through repeated installation cycles. Aging Test

Up to 48-hour aging test ensures reliability. Power Consumption Test

Checked for world-class energy efficiency. Temperature and DC Margin Test

Ensures that the motherboard is capable of coping with Voltage fluctuations caused by varying temperatures. Thermal Shock Test

Ensures ability to survive temperature changes during transportation. Non-Operation Shock Test

Built to withstand jolts that may occur during shipping. Burn-In Test

Every component is checked to ensure flawless operation in any environment. Installation Test

Connector placement is double-checked to ensure hassle-free installation. Drop Test

Drop tests from various heights ensure durability. Salt and Spray Test

Tested for I/O reliability, prolonged lifespan and rust-resistance.

Superb Performance

DDR4 Support

With DDR4, you'll accelerate memory frequencies up to an incredible to 3200MHz! And ASUS works with almost every DDR4 memory vendor, so you're assured the best compatibility.

* Specifications and features vary by model, and all images are illustrative. Please refer specification pages for full details.

Optimized Cooling

Fan Xpert

Dedicated CPU and case fan controls

Exclusive Fan Xpert ensures every fan achieves the best balance of cooling performance and low noise - and with Prime A320 series boards and their hardware-level 4-pin/3-pin PWM/DC mode for case fans, a simple BIOS adjustment lets you run your case fan in PWM/DC. Fan Xpert even includes Auto-Tuning mode to scan and detect all fan characteristics for single-click customization!

* Specifications and features vary by model, and all images are illustrative. Please refer specification pages for full details.

Game in Your Way

Gaming Audio

Combined onboard features deliver elevated audio

Intelligent design and premium hardware create audio quality unlike anything you've ever experienced!

* Specifications and features vary by model, and all images are illustrative. Please refer specification pages for full details.

All-round Energy Saving

Energy Efficient Design EPU With the Energy Processing Unit (EPU) you'll enjoy system power savings. EPU automatically optimizes power consumption, and maximizes savings with Away mode.

Ultrafast Transfer Speeds

10Gb/s USB 3.1 Onboard

With backward-compatible USB 3.1 Type-A, you'll experience ultimate connection flexibility and blazing data-transfer speeds of up to 10Gb/s (twice as fast as standard USB 3.0). Speed Up with Onboard M.2 Up to 32Gb/s

With x4 PCI Express 3.0/2.0 bandwidth, M.2 supports up to 32Gb/s data-transfer speeds. It is the perfect choice for an operating system or application drive, making your whole PC or professional apps work as fast as possible. * Specifications and features vary by model, and all images are illustrative. Please refer specification pages for full details.

Easy PC DIY

Q-Slot

Effortless PCI Express component removal



The large winged clip is easy to reach and easy to operate. Just press the Q-Slot clip lightly, and the graphics card pops out. Installing or removing even the biggest graphics cards is no sweat! Q-DIMM

Easy memory removal



Even if you work with a smaller case, just push down on the one-sided clip and push or pull RAM modules in or out - removing memory is that simple!

One-Stop Controls

Media-Acclaimed UEFI BIOS

The smoothest, slickest mouse-controlled graphical BIOS has been improved to make it even more appealing. Whether you're a PC novice or a seasoned overclocker, EZ and Advanced modes help you find your way, quickly and easily.

EZ Flash 3

Update the BIOS via the internet, without leaving the BIOS interface. S.M.A.R.T

Check your storage device Self-Monitoring, Analysis, and Reporting Technology logs to gauge reliability and possibly to determine potential failures. Q-Fan Control

You can configure the fan's operating speed manually, or use the easy pre-configured fan profiles to select Standard, Silent, Turbo, or Full Speed modes! My Favorite

Quickly find tuning options and add preferred tools to the list. EZ Mode Intuitive graphical fan control - Fine-tune individual fans simply by dragging a curve with the mouse.

EZ XMP - Improve DRAM performance with a click.

SATA information - Easily display SATA port details for device identification.

Fast clock adjustment - Use mouse controls to quickly change time and date settings. Advanced Mode Last modified log - Track last change and save preferred profiles onto a USB drive.

SATA port renaming - Rename SATA ports for easy identification.

AI Suite 3

One-stop access to innovative ASUS features

ASUS AI Suite 3 offers a brand-new user experience through a clearer and more attractive interface with support for larger monitors. It consolidates all exclusive ASUS features into one simple-to-use package, allowing you to supervise overclocking, energy consumption, fan speeds, voltages and more. This all-in-one app offers diverse and easy-to-use functionality, with no need to switch back and forth between different utilities.

AMD CPU and Chipset Features