» Campbell has missed two straight games after suffering an abdominal injury Week 4 against the Oakland Raiders. The 2019 second-round pick out of Ohio State underwent a minor procedure on Oct. 4, according to Reich, but was able to make his return to practice this week; he was a limited participant on Wednesday and Thursday. With Campbell out, the team has seen Zach Pascal, Chester Rogers and Deon Cain get added snaps behind starter T.Y. Hilton, while Pascal has filled in Campbell's role as kickoff returner.

» Desir suffered a hamstring injury in the Colts' Week 5 victory over the Kansas City Chiefs, and has been listed on the team's injury report since. He did not practice last week as the team prepared for their Week 7 game against the Houston Texans, but was able to play, logging seven tackles and two passes defensed, as well as his first interception of the season. Depending on the status of fellow starting cornerback Kenny Moore II, Desir, who did not practice Wednesday and was limited on Thursday, could be spelled by a mix of players if he's limited or can't play this Sunday, including Rock Ya-Sin, Quincy Wilson, Marvell Tell III or Shakial Taylor.

» Doyle (groin) first appeared on the injury report this week on Friday. The seventh-year tight end this season is third on the team in receptions (17), fourth in receiving yards (149) and also has a receiving touchdown on the year. If Doyle is limited or can't play Sunday, look for Eric Ebron and Mo Alie-Cox to get added snaps at tight end; the team also has tight end Ian Bunting on its practice report if needed.

» Lewis suffered an ankle injury during the second quarter of the Colts' Week 3 matchup against the Atlanta Falcons; he was able to return to practice for the first time Wednesday, and was a limited participant in the team's first two practices this week to prepare for Sunday's game against the Broncos. Lewis this season has appeared in two games and has one tackle; he had 13 tackles (three for a loss) with two sacks, eight quarterback hits and one pass defensed in eight games as a rookie last season. Other options along the defensive line for the Colts should Lewis be limited or out include Grover Stewart, Margus Hunt and Trevon Coley.