The first trailer for Dallas Buyers Club has gone online. Based on a true story, the film stars Matthew McConaughey as a Texas electrician who, after being diagnosed with AIDS in 1986, began to smuggle alternative and illegal treatments into the US and into the hands of other patients. If you can look past the irritating Entertainment Tonight anchor chirping over the trailer, you can see a movie that has a surprising mix of both drama and comedy with McConaughey’s character posing a priest to get past border security. There’s also an eye-catching look at Jared Leto co-starring as a transsexual. This movie is on my must-see list for Toronto International Film Festival, and this trailer does nothing to change that.

Hit the jump to check out the trailer along with some new images. The film also stars Jennifer Garner, Steve Zahn, Dallas Roberts, Griffin Dunne, Denis O’Hare, and Bradford Cox. As we reported yesterday, Dallas Buyers Club will open on November 1st and will expand nationwide over the following weeks. [Update: We updated the article with the debut poster.]

Click over to Apple to watch the full trailer in HD. We’ll have an ET-less embed up as soon as one’s available.

Images via The Film Stage

Here’s the synopsis for Dallas Buyers Club: