Two prisoners have been found dead in their cell at Silverwater jail.

Staff from Corrective Services of NSW found the two inmates, aged 41 and 47, during the morning head count of the Metropolitan Remand and Reception Centre about 6.15am on Monday.

"A crime scene was established and the NSW Police Force immediately notified," a spokeswoman from Corrective Services of NSW said.

A NSW police spokeswoman said investigations were continuing.

"The bodies were discovered during morning inspection today. Post-mortem examinations will assist detectives with determining the chain of events that led up to the deaths," she said.

An Ambulance Services of NSW source said it was a call out for a "cardiac or respiratory arrest" as the medical conditions of both the deceased.

A report will be prepared for the Coroner.

The Metropolitan Remand and Reception Centre at Silverwater is a maximum security facility housing about 900 male inmates who are awaiting their respective trials.