The Pennsylvania Department of Health has now confirmed 479 coronavirus cases in Pennsylvania, including the first in Dauphin County. That’s up from 371 cases on Saturday.

This marks the second straight day where Pennsylvania’s new case count has topped 100; there were 103 cases added on Saturday. The virus has now been confirmed in patients in 33 counties, though the heaviest concentrations remain in Philadelphia, its suburban counties, and the adjacent Lehigh Valley.

In the midstate, there are now 37 confirmed cases, led by 11 in Cumberland County.

There have been two deaths of Pennsylvania residents, though officials said Saturday that a New Jersey resident who was being treated at a Lehigh Valley Hospital for COVID-19 symptoms had also died.

Sunday’s case count comes one day before state officials have pledged to begin enforcing a business closure order imposed by Gov. Tom Wolf on all “non-life sustaining businesses.” That order, which has generated a lot of pushback from the affected business sectors and Republican lawmakers, is supposed to take effect at 8 a.m. Monday.

In the interim, Wolf Administration officials continued to work on waiver requests filed by specific companies that seek an exemption to stay open, even as officials started to explore even more steps, like a general shelter-in-place order generally reserved for specific and short-lived weather or public safety emergencies.

With the virus having been confirmed in all nearly regions of the state, health officials believe Pennsylvania has entered a make-or-break stretch in which social distancing, attention to cleanliness and strict isolation of ill people will be essential to preventing a spike in cases that could overwhelm the state’s hospital network.

Given the downswing in seasonal flu, state Heath Secretary Rachel Levine said Saturday that health officials can increasingly presume anyone with these symptoms - a cough, fever and shortness of breath sometimes accompanied by gastrointestinal upset - has COVID-19. She encouraged people experiencing mild symptoms to stay home.

The secretary continued to urge everyone to take personal precautions like frequent hand-washing, and she urged anyone who is feeling sick not to attend any event or otherwise be around gatherings of people.