The number of confirmed cases of coronavirus across New York state rose Wednesday to 212, while the five boroughs have now tallied 48 positive diagnoses, according to Gov. Andrew Cuomo.

Those totals represent a statewide increase of 39 and a city spike of 12 from Tuesday, as the potentially deadly disease continues to surge in the Empire State, home to more cases than any state in the nation except Washington.

New York’s hardest-hit county remains Westchester, which has 13 new cases for a total of 121.

Starting Thursday, the National Guard will begin enforcing a one-mile-radius “containment area” in the city of New Rochelle, forcing the two-week closure of large gathering areas including schools and houses of worship.

Cases continued to rise on Long Island, where Nassau County now has 28, an increase of nine, and Suffolk County has six, an increase of five.

Tallies in Rockland, Saratoga and Ulster counties stayed static, meanwhile, at six, two and one, respectively.

Still, Cuomo urged calm.

“The facts here do not justify the amount of fear,” he said. “The facts here actually reduced the anxiety. We have 212 cases in the state of New York. [Just] 32 are hospitalized.”