The Broncos are 2.5-point underdogs to the visiting Patriots, but history may suggest otherwise. In eight career games in Denver, Brady has a career record of 2-6. The wins coming against current ESPN analysts Danny Kanell and Tim Tebow.

Replacing Bledsoe: Since taking over for Drew Bledsoe in 2001, Brady has dominated the league, but the Mile High City has been his kryptonite. His first career start in Denver came in 2001, and ended in a 31-20 win for the Broncos, led by Brian Griese. In the game, Brady threw four fourth quarter interceptions. The outing was Brady’s worst career start in Denver.

The Safety: In a 2003 Monday Night Showdown, Brady got his first victory in what was the infamous intentional safety game. While down 24-23, Belichik elected to take an intentional safety when the team was facing 4th and 10 on their own goal line and 2:51 remaining.

At the time, the Patriots had the No. 1 defense in the league, and still possessed all three timeouts. The Patriots defense forced a punt, and on the following drive, the game ended with Brady throwing an 18-yard touchdown pass to David Givens with 30 seconds left in the game and securing a 30-26 Patriots victory.

Starting at quarterback for the Broncos was Danny Kanell in place of the injured Jake Plummer.

Champ saves the day: 2005 brought Brady and the Patriots a pair of losses. Week 6, the Pats were facing a 28-3 deficit in the third quarter, and rallied to score 17 unanswered second half points, ultimately losing 28-20.

The Patriots returned to Denver for a Divisional Round matchup with Mike Shannahan’s Broncos. The Broncos won the game 27-13, and is remembered for Champ Bailey’s 103-yard interception return. While down 10-6, the Patriots were driving for the go-ahead score, and were facing third and goal from the Broncos 5-yard line.

Facing pressure, Brady threw the ball up for grabs and Bailey made him pay. Bailey jumped in front of Troy Brown, and returned the ball 103 yards, before being pushed out of bounds by Benjamin Watson at the 1-yard line. The play is the longest interception return in the longest non-scoring play in NFL playoff history.

The Broncos never let go of the momentum, once again sending the Patriots home with a loss, before losing the AFC Championship to the eventual Super Bowl Champion Pittsburgh Steelers.

McDaniels Era: The Patriots didn’t return to Denver until 2009. Under first-year head coach Josh McDaniels, Denver defeated New England 20-17 in Overtime with a first possession field goal by Matt Prater.

Brady had a decent game, completing 19-of-33 passes for 219 yards, and a pair of touchdown passes. Unfortunately for him and the dark overlord himself Bill Belichik, the all-time great was outmatched by Kyle Orton, who had one of his best games as a Bronco. Orton completed 35 passes, on 49 attempts, for an impressive 330 yards, along with a pair of touchdown passes and a lone interception.

The Broncos wearing the infamous yellow and brown throwback uniforms to commemorate the 50-year anniversary of the AFC moved to 5-0 under McDaniels.

Brady silences Tebow-mania: After winning six straight, the Broncos hosted hosted the foes from New England in a Week-15 matchup. Brady torched Denver for 320 yards and a pair of touchdowns in a 41-23 Patriots victory.

Denver would go on to lose the two remaining regular season games before defeating the Pittsburgh Steelers in an Overtime thriller in the first round of the Playoffs. The Broncos would then make the trip to Foxborough. Once again the Broncos were defeated by Brady and the Patriots 45-10. Tim Tebow’s time as a Bronco ended shortly after.

AFC Championship showdown: For all the talk about Peyton Manning falling short in the playoffs, the 2013 AFC Championship game was one of the finest of his career. The Broncos defeated the Patriots 26-16, and the game was not really even as close as the score indicates.

Manning was nearly flawless, posting a 118.4 QBR. Manning was 32-of-43 for 400 yards, and a pair of passing touchdowns.

Brady was impressive in his own right, throwing for 277 yards and a touchdown.

Brock Osweiller slays Goliath: Most recently Brady and the Patriots were defeated Nov. 29 in a Sunday Night Football overtime thriller. Down 14 points in the fourth quarter, Osweiller led the Broncos back to defeat the visiting Patriots 30-24 in OT. On the third play from scrimmage in the extended time period, C.J. Anderson rushed for a 48-yard game-winning touchdown.

The loss was Brady’s sixth in Denver, and the Patriots first of the season. If history repeats itself, like it often does, the Broncos might have a better shot this Sunday than the experts give them. Every Superman has his kryptonite, and the Mile High City is Brady’s.