A literal hit-and-run driver in Queens fled on foot after fatally striking one woman and sending another to the hospital early Tuesday, cops said.

An unidentified 56-year-old woman was driving a burgundy Honda CRV on 126th Street in South Ozone Park around 1:15 a.m. when a gray Lexus SUV blew through a red light at 111th Avenue and smashed into the Honda’s passenger side, police said.

The impact sent the Honda barreling in to the facade of Elegant Floral Design, and 72-year-old Gilda Lascano flying through the windshield and under a nearby parked car, police said.

“The burgundy Honda SUV was on the curb and she was under the car. I was just focused on her. I was trying to see whether she was alive or there were any signs of life but there wasn’t,” said the Lascano’s neighbor, Joel Rios, 28. “The woman in the car was screaming in pain. I didn’t hear any words, just screams.”

He added: “It’s sad because her daughter told me she was coming from work. She was trying to tell her to retire.”

Neighbors say they spotted beer cans near the smashed up Lexus. The driver fled the scene on foot, according to police.

“It’s tragic. It’s a scary situation to know the driver is still on the run,” said neighbor Ome Persaud.

The unidentified driver of the Honda was taken to Jamaica Hospital in stable condition.