Melbourne's women's team has suffered a double blow with Meg Downie and Stephanie De Bortoli both ruled out for the rest of the season.

Downie has been grounded due to a ruptured hamstring while De Bortoli has undergone surgery to repair an Achilles tendon injury.

Downie was also knocked out by Collingwood's Sophie Casey on Saturday night and had to be taken from the ground on a stretcher in the final quarter of the Demons' 19-point win over the Magpies.