Clive Palmer has filed $10 million lawsuits against Prime Minister Malcolm Turnbull and Employment Minister Michaelia Cash over allegedly defamatory comments they made about the demise of Queensland Nickel.

Documents lodged in the Brisbane Supreme Court this week claim the Prime Minister and Senator Cash conveyed at a press conference on April 15, 2016, that Mr Palmer had used funds from the company for his own benefit.

It further stated the pair, who are being pursued separately, indicated Mr Palmer had acted to the detriment of QNI employees, their families and the Townsville community at large.

Their remarks conveyed the imputation that Mr Palmer is a "greedy self-serving entrepreneur who does not care for the welfare of his employees and ordinary Australians", the documents claim.