Boston Dynamics' new "Atlas" robot is a game changer, not just for companies, but for society, Insider.com CEO Jason Calacanis said Wednesday.

"This is really the end of manual labor. When you watch this video, he's walking through the snow; he's wobbly, but he gets back up," the tech investor told CNBC's "Squawk Alley."

"Manual labor is going to end in our lifetime, and in this video you can see how close we really are. It's a huge societal issue with jobs, but it's going to be a huge lift in terms of efficiency of companies that nobody expected."