Dr. David O'Gurek, an associate professor of family and community medicine at Temple who runs a buprenorphine program out of his family medicine practice, explains that "one of the big issues with any substance-use disorder is not the actual use. It is sort of what happens between uses." The harmful behavior that is associated with addiction comes from the worry that people in addiction have about being well — by using again — once the levels of drugs in their body start to drop. By taking Suboxone which does not lead to euphoria but satisfies the physical craving for opioids, O'Gurek explains, a person in addiction "avoids that cycle of developing euphoria and falling into that fear state that you are going to get sick, or what is going to happen if you get sick, that you need to use to get better."