American Bridge, the super PAC founded by Democratic strategist David Brock, is launching its first 2018 campaign with an ad targeting several GOP senators over Secretary of State nominee Rex Tillerson.

The effort includes promoted Facebook posts specifically targeting Sens. Jeff Flake Jeffrey (Jeff) Lane FlakeHow fast population growth made Arizona a swing state Jeff Flake: Republicans 'should hold the same position' on SCOTUS vacancy as 2016 Republican former Michigan governor says he's voting for Biden MORE (R-Ariz.), Dean Heller Dean Arthur HellerOn The Trail: Democrats plan to hammer Trump on Social Security, Medicare Lobbying World Democrats spend big to put Senate in play MORE (R-Nev.), and Marco Rubio Marco Antonio RubioOvernight Defense: Pentagon redirects pandemic funding to defense contractors | US planning for full Afghanistan withdrawal by May | Anti-Trump GOP group puts ads in military papers Democrats step up hardball tactics as Supreme Court fight heats up Press: Notorious RBG vs Notorious GOP MORE (R-Fla.) in major metropolitan areas within each state.

The separate posts ask if the individual senators will “bow down to Russia.”

The American Bridge buy also includes a digital ad featuring cable news reports of Republican senators, including Sen. John McCain John Sidney McCainThe Memo: Trump's strengths complicate election picture Mark Kelly: Arizona Senate race winner should be sworn in 'promptly' Cindy McCain: Trump allegedly calling war dead 'losers' was 'pretty much' last straw before Biden endorsement MORE (R-Ariz.), expressing concern over Tillerson’s connections to Russia.

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“American Bridge is launching these ads to highlight the alarmingly close ties between Tillerson and Vladimir Putin and the grave threat a pro-Putin State Department would pose to our nation’s security,” said American Bridge President Jessica Mackler.

Heller and Flake are both up for re-election in 2018. Rubio, though not up for re-election, could cast a shadow over Tillerson’s nomination by voting no during the Foreign Relations Committee hearing.

Rubio has already said he has “serious concerns” about the ExxonMobil CEO's ties to Russian President Vladimir Putin.

Flake, who also sits on the Foreign Relations Committee, suggested earlier this week that he is maintaining an open mind on Tillerson.

“Donald Trump Donald John TrumpBiden on Trump's refusal to commit to peaceful transfer of power: 'What country are we in?' Romney: 'Unthinkable and unacceptable' to not commit to peaceful transition of power Two Louisville police officers shot amid Breonna Taylor grand jury protests MORE’s nomination of Rex Tillerson -- a close Putin ally -- is a critical opportunity for Americans across the political spectrum to come together and reject Russia’s unprecedented attacks on our democracy,” Mackler said.

“At stake in this nomination fight is whether our country will stand up against the Kremlin’s cyberattacks or bow down to Russian aggression.”