In the first long-term study of the health impacts of the World Trade Center (WTC) collapse on September 11, 2001, researchers at The Mount Sinai Medical Center in New York have found substantial and persistent mental and physical health problems among 9/11 first responders and recovery workers.

The data are published this week in a special 9/11 issue of the medical journal The Lancet.

The Mount Sinai World Trade Center Clinical Center of Excellence and Data Center evaluated more than 27,000 police officers, construction workers, firefighters, and municipal workers over the nine years following 9/11 and found a high incidence of several conditions, including asthma, post-traumatic stress disorder (PTSD), depression, sinusitis, and gastroesophageal reflux disease (GERD). More than one in five of all the responders studied had multiple physical and/or mental health problems.

The results showed that nine years after 9/11:

28 percent of patients had asthma, 42 percent had sinusitis, and 39 percent had GERD.

42 percent of patients had abnormal lung function tests, indicative of lung injury.

7 percent of police officers were diagnosed with depression, 9 percent with PTSD and 8 percent with panic disorder.

28 percent of other rescue and recovery workers had symptoms of depression; 32 percent experienced symptoms of PTSD, and 21 percent had symptoms consistent with panic disorder.

Almost 10 percent of rescue and recovery workers had asthma, sinusitis, and GERD simultaneously.

48 percent of rescue workers with asthma, 38 percent with sinusitis, and 43 percent with GERD were also diagnosed with at least one mental health condition.

"Several studies have evaluated the health impacts of 9/11, but this is the first long-term study to demonstrate the lasting burden of disease experienced by the brave men and women who responded in the aftermath of the terrorist attacks at the World Trade Center," said Juan Wisnivesky, MD, DrPH, Vice-Chair for Research in the Department of Medicine and lead author on the study. "Our findings underscore the importance of long-term monitoring and treatment of the rescue and recovery worker population."

Those who arrived on the scene first received the greatest exposure to the dust and smoke, and sustained the most severe health damage. These first responders were exposed to a complex mix of toxins and known human carcinogens that included benzene from jet fuel, asbestos, dioxin, lead, polycyclic aromatic hydrocarbons (PAHs), glass fibers, hydrochloric acid, polychlorinated biphenyls, and other caustic chemicals. All of these materials were released into the air of lower Manhattan with the collapse of the towers. Participants were divided into four categories based on their level of exposure to airborne toxins at Ground Zero. Fourteen percent were categorized as low exposure, 65 percent as intermediate, 18 percent high, and 3 percent as very high.

"These men and women risked their lives and their health to support their fellow Americans after the devastation of 9/11," said Philip Landrigan MD, Principal Investigator of the Mount Sinai WTC Program's Data and Coordination Center, Dean of Global Health and Chair of the Department of Preventive Medicine, Mount Sinai School of Medicine. "Now, many of them are riddled with multiple health problems. Our study shows that these diseases may persist for years to come. We should do everything in our power to provide the best long-term care possible to these heroes."