The MacArthur Foundation, known for bestowing its annual “genius” grants on artists, actors and other creative people, on Wednesday announced the eight semifinalists in a new competition: come up with the best proposal to solve a global problem, with a reward of $100 million.

Out of more than 1,900 proposals submitted, the foundation’s judges chose eight with goals that include eliminating river blindness in Nigeria, educating displaced children in countries like Syria, and caring for children in orphanages.

From those eight, the foundation’s 11-member board will select up to five finalists in September, who will then present their proposals in a live event in December, the foundation said, before the winner is named.

Here are the eight semifinalists. Which would you choose?

Problem: Orphanage care

“Residential care causes long-term negative effects on children’s physical, intellectual, and psychosocial development,” the foundation said in a statement.