Perseveration: A major downside of Asperger Syndrome Perseveration is perhaps one of the biggest downsides to Aspergers. It can affect the ability to thrive in life, both by alienating friends and by putting brakes on certain workplace interactions that play a role in career progress. Unfortunately, on the Aspie's side of an interacton it can be hard to detect perseveration is occurring, and the result can be an unforseen burst of anger from the other party in a conversation. As a result social interaction can become even more worriesome and energy-draining going forward, because of the need to steel oneself for the potential of unexpected negativity or anger on the other side without an easily understandable cause.

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