Crohn's disease is a complex disorder of the immune system which causes chronic and severe inflammation of the gastrointestinal tract. Symptoms include severe pain the abdomen, bleeding in the gastrointestinal tract, diarhea and excessive weight loss. Apart from these symptoms, the disease can sometimes also cause certain extrinsic symptoms such as arthritis, skin rashes, and lack of concentration. The disease is a fatal condition of the body resulting in permanent damage and death.While, the cause of this serious disease of the body is still unknown, it is mainly caused by a complex interplay of certain genetic, environmental and autoimmune factors. Most of the anti inflammatory drugs used to treat this condition are generally associated with certain serious and harmful side effects like bleeding etc. So far there is no permanent and surgical cure for this complicated disease. The current treatment available today are only targeted at treating symptoms, preventing frequency of relapses and controlling remissions.However, in the recent years, there is new buzz about treating crohn's disease with low dose naltrexone. Naltrexone is basically an opioid receptor antagonist used for the treatment of alcoholism and drug addiction in many drug addict and alcoholics. A standard dose of 50 mg naltrexone per day has been known to reduce opioid cravings along with negating the intoxicating effect produced by the opiod substance or alcohol resulting in final quitting of the alcohol or opioid drugs.