Metabolic Tracking (MT): The crew set up the hardware and materials to support two separate sessions of thawing and inoculation today for the MT investigation. They injected the thawed inoculum into multiwell BioCells, and inserted them into a NanoRacks Plate Reader. Samples were placed into a Minus Eighty Degree Celsius Laboratory Freezer for ISS (MELFI). The Metabolic Tracking investigation evaluates a rapid, low-cost method for assessing the effects of therapeutic compounds in microgravity. The method contributes to development of custom plans for emergency medical treatment for crew members, using primary tissue samples. This investigation also determines the feasibility of developing improved pharmaceuticals in microgravity using a new method to test the metabolic impacts of drug compounds. This could lead to more effective, less expensive drugs.

Human Research Program (HRP) Collections (Biochemical Profile and Repository): A 53S crewmember collected urine samples for his FD120 sessions of the Biochem Profile and Repository investigations.

The Biochemical Profile experiment tests blood and urine samples obtained from astronauts before, during, and after spaceflight. Specific proteins and chemicals in the samples are used as biomarkers, or indicators of health. Post-flight analysis yields a database of samples and test results; which scientists can use to study the effects of spaceflight on the body.

Repository is a storage bank used to maintain biological specimens over extended periods of time and under well-controlled conditions. The repository supports scientific discovery that contributes to our fundamental knowledge in the area of human physiological changes and adaptation to a microgravity environment and provides unique opportunities to study longitudinal changes in human physiology spanning many missions.

Space Station Computer (SSC) Printer Deploy: Earlier today, the crew installed the new HP Printer, brought to ISS by SpaceX-14, in the US Lab. Crew reported excellent print quality from the new printer. The legacy Epson printer will be kept onboard as a backup unit.

Integrated Communications Unit (ICU) R4 Software Transition: Yesterday, ground teams redirected Joint Station LAN (JSL) network traffic to KU Communication Unit (KCU) 2 in order to update KCU 2 Kernal 0 with the new R4 Software. Today the crew installed a Gigabit Ethernet cable from KCU 2 to the JSL router and loaded R4 to KCU 2 Kernal 1 while ground teams loaded the new firmware/coefficient files. After the loads were complete, ground teams activated KCU 2. This completes the first part of the ICU R4 software transition. The second part of the transition, the load of R4 to KCU 1 Kernal 0 and Kernal 1, will be scheduled in about 1 week to allow for testing of the new Ku-Band return link data rates of 450 and 600 mbps during defined test windows on GMT 110, 111, and 112. The intent of ICU R4 is to increase the return link bandwidth from 300 Mbps to 600 Mbps.

Eye Exams: This morning the 54S crew completed routine Optical Coherence Tomography (OCT) and Fundoscope eye exams. Eye exams are routinely performed onboard to monitor crewmembers eye health. Eyesight is one of the many aspects of the human body that is affected by long-duration stays in a microgravity environment.

Oxygen Generation System (OGS) Activated Carbon/Ion Exchange (ACTEX) Replacement: Earlier today the crew collected samples from the OGS recirculation loop for return and replaced the ACTEX cartridge. This loop sample is performed every 180 days and the ACTEX cartridge is changed out every 730 days as part of scheduled ISS preventative maintenance.

Dragon Cargo Operations: The crew has completed more than 42 hours of unloading and loading of the Dragon vehicle. At this time cargo specialist on the ground estimate the crew will need approximately 31 hours to complete the Dragon vehicle packing in preparation for Dragon unberth, planned on 02-May.

Space Station Remote Manipulator System (SSRMS) Operations: Later today, controllers will use the SSRMS and Special Purpose Dexterous Manipulator (SPDM) to transfer the MISSE Sample Container (MSC) from the MTT to the MISSE Flight Facility (FF).

Today’s Planned Activities

All activities are complete unless otherwise noted.



HRF Generic Urine Collection

HRF Generic Sample MELFI Insertion Operations

СОЖ maintenance

Mouse Blood drawing Familiarization

Check the Results of Antivirus Scanning on [ВКС] Auxiliary Computer System Laptops; Report the Status

APEX-06 MELFI Insertion #2

Mouse Stress Defense Item Gathering

PHASE TRANSITION. Experiment Setup and Start of Operations.

Hardware Setup for the PAO Event. Check Video and Audio Signals.

ZBOOK Hard Drive Installation

SSC HP Printer Deployment to Replace Lab SSC Epson Printer

Crew Preparation for the PAO Event

TV Session with Artek Children and Youth Center

Station Support Computer (SSC) 17 Laptop Relocate

XF305 Camcorder Setup

Glove Box Bench Setup

BIOCARD. Assistance during the Experiment

BIOCARD. Experiment Operations.

Health Maintenance System (HMS) OCT Setup

Mouse Stress Defense Cage Maintenance for Water 3

KU Comm Unit Cable Route

Metabolic Tracking Inoculation Preparation

Crew Preparation for the PAO Event

TV Session with Moscow Economic School Students

Spaceflight Cognitive Assessment Tool for Windows (WinSCAT) Test

Metal Oxide (METOX) Regeneration Termination

PHASE TRANSITION. Closeout Operations.

Metabolic Tracking MELFI Metabolic Tracking Group Retrieve

Metabolic Tracking Biocells Inoculation

Comm Config for Communication from MRM1

SEPARATION. Fitting of Delivered Panel #205.

ZBOOK Hard Drive Installation

SEPARATION. Installation of the Mounting Hardware of the БД Distillation Unit and БЕ Reservoir Unit

Health Maintenance System (HMS) – OCT Exam

SEPARATION. Hoses Mating and Routing behind the Panels (including БД Installation behind Panel 205).

Metabolic Tracking Plate Reader Insertion/Removal

Health Maintenance System (HMS) OCT Stow

Metabolic Tracking Session Cleanup

SSC HP Printer Checkout

In Flight Maintenance (IFM) Oxygen Generation System (OGS) Gather

Public Affairs Office (PAO) High Definition (HD) Config LAB Setup

Galley food warmer door troubleshoot

SEPARATION. БВ Vacuuming Unit Installation.

PAO Preparation

Public Affairs Office (PAO) Event in High Definition (HD) – Lab

In Flight Maintenance (IFM) Oxygen Generation System (OGS) Internal ACTEX Pre-Flush

Public Affairs Office (PAO) Social Media Event

Restoration of the Nominal Comm Config

24-Hour ECG Recording (start)

Metabolic Tracking Inoculation Preparation

ISS HAM Service Module Pass

Oxygen Generation System (OGS) Internal ACTEX Remove and Replace

Metabolic Tracking MELFI Metabolic Tracking Group Retrieve

Metabolic Tracking MELFI Inoculation Bag Retrieve

Metabolic Tracking Biocells Inoculation

Private Medical Conference (PMC)

APEX-06 Adjust Light

Cargo Transfer to Dragon

VZAIMODEISTVIYE-2. Experiment Operations

Metabolic Tracking Session Cleanup

In Flight Maintenance (IFM) Oxygen Generation System (OGS) Stow

Dragon Cargo Operations Conference

HRF Columbus HD Video Setup

Completed Task List Activities

None

Ground Activities

All activities are complete unless otherwise noted.



MISSE MSC Transfer

ICU R4 Software Transition

LAB MCA Full Calibration

Three-Day Look Ahead:

Wednesday, 04/18: JSL Firewall Deploy, PCG9 Sampling, CIR Bottle R&R, NORS O2 Transfer, Mouse Stress Defense Ops, Metabolic Sampling, ISS Reboost

Thursday, 04/19: LAB IMV Valve R&R, Mouse Stress Defense Ops, Miniature Exercise Device Ops, N3 MCA VGA R&R

Friday, 04/20: MSL Furnace Swap, APEX6 Harvest, Mouse Stress Defense, EIISS, PEPS Inspection, MSG VUE Removal

QUICK ISS Status – Environmental Control Group: