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Newswise — lNDIANAPOLIS, Sept. 8, 2013 — With water pipes or hookahs gaining popularity in the United States and other countries, scientists today described a step toward establishing the health risks of what has been termed “the first new tobacco trend of the 21st century.” In a study that they said provides no support for the popular notion that hookahs are safer than cigarettes, they reported that hookah tobacco and smoke contain lower levels of four toxic metals than cigarette tobacco and smoke. It was part of the 246th National Meeting & Exposition of the American Chemical Society (ACS), the world’s largest scientific society, being held here this week.

“Any form of smoking is dangerous, and our studies on toxic metals in hookah smoke are taking the first steps toward the necessary animal and human studies that will establish a clearer picture of the relative dangers of hookah and cigarette smoking,” said Joseph Caruso, Ph.D., who led the study. “It is very difficult to compare hookah smoking with cigarette smoking because they are done so differently.” He explained that water pipes use specially prepared tobacco, sometimes called shisha — a moist, gooey concoction that may include molasses, honey and flavoring agents. Burning embers or charcoal heat the shisha, producing smoke that bubbles down through a container of water and into a long hose-like tube with a mouthpiece for inhaling.

Caruso and colleagues, who are with the University of Cincinnati, think that the lower levels of arsenic, lead, cadmium and chromium they detected in hookah smoke are not due to filtering of the smoke through water. That’s part of the basis for the popular belief — disputed by the U.S. Centers for Disease Control and Prevention, the American Lung Association and other authorities — that hookah smoking is safer than cigarettes. Rather, it seems that shisha itself may contain lower levels of those metals, since Caruso’s team did not detect excess amounts of those metals in the hookah water.

Other differences in hookah vs. cigarette smoking complicate any interpretation of the health implications of the lower levels of toxic metals in hookah smoke, noted Caruso and graduate student Ryan Saadawi, who presented on the research at the meeting.

Studies have shown, for instance, that a typical hour-long hookah smoking session involves 200 puffs, while an average cigarette is 20 puffs. The World Health Organization estimates that an hour-long hookah session is equivalent to smoking 5-10 packs of cigarettes. However, many people who smoke shisha smoke less frequently than cigarette smokers.

“All of these things make hookah smoking different from cigarette smoking, and it also makes it difficult to compare the two, which is partly the reason why there are so few studies on the topic,” said Saadawi. Caruso and Saadawi studied unsmoked shisha, as well as shisha smoke, with a sensitive instrument called an inductively coupled plasma mass spectrometer. They also removed the additives from the shisha and found little difference before and after, thus the tobacco is the likely source of the metals, they said. Whether the smoke went through the water in the hookah also didn’t affect the metal levels.

The scientists acknowledged funding from the University of Cincinnati. Saadawi has a fellowship from the Saudi Arabian Cultural Mission. An abstract of the presentation appears below.

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Title Total analysis in hookah tobacco formulation and hookah tobacco smoke

Abstract Various studies have been performed on cigarette, cigar, and pipe tobacco while virtually no studies have been performed on hookah tobacco. It is well documented the former tobacco is known to contain toxic metals such as As, Cd, Cr, and Pb. However, little is known about the metal content in hookah tobacco. Hookah has been popular in the Middle East and surrounding regions for ages and its use is emerging rapidly in Western cultures making it imperative to study.

Microwave assisted digestion in combination with ICP-MS was utilized to elucidate the toxic metal content in an array of different brands/flavors of hookah tobacco formulations as well as hookah tobacco smoke. A water extraction was done on the hookah tobacco formulation to remove water soluble glycerin, molasses/honey, colorants and flavorings. Polycyclic aromatic hydrocarbons were extracted from hookah tobacco smoke using an organic solvent and analyzed by HPLC florescence detection.