Vice President Pence said Saturday that President Trump's Supreme Court nominee Neil Gorsuch will be confirmed by the Senate "one way or the other" ahead of a likely Senate showdown next week.

Pence's vow echoed remarks from other top Republicans who have signaled support for potentially invoking the so-called nuclear option, changing Senate rules to confirm Gorsuch with a simple majority vote.

"For the sake of our Supreme Court, for the sake of our country, for the sake of our Constitution, we will overcome the obstructionists and the United States Senate will confirm Judge Neil Gorsuch one way or the other," Pence said at a speech in Columbus, Ohio.

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Pence's comments come ahead of a potentially bitter fight in the Senate likely to take place in the coming week over Gorsuch's nomination.

Republicans, who hold 52 seats, have scrambled to secure the support of eight Democratic senators to reach the 60 votes required under current Senate rules to confirm the Supreme Court nominee.

Sen. Claire McCaskill Claire Conner McCaskillDemocratic-linked group runs ads in Kansas GOP Senate primary Trump mocked for low attendance at rally Missouri county issues travel advisory for Lake of the Ozarks after Memorial Day parties MORE (Mo.) on Friday became the latest Democrat to say they will vote to support a filibuster of Gorsuch, shrinking the number of Democrats who have undecided or unclear positions on Gorsuch to nine, according to The Hill's Whip List.

So far, 38 Democrats have vowed to filibuster Gorsuch while only two Democrats – Sens. Joe Manchin Joseph (Joe) ManchinOVERNIGHT ENERGY: House Democrats tee up vote on climate-focused energy bill next week | EPA reappoints controversial leader to air quality advisory committee | Coronavirus creates delay in Pentagon research for alternative to 'forever chemicals' Senate Democrats demand White House fire controversial head of public lands agency House Democrats tee up vote on climate-focused energy bill next week MORE (W.Va.) and Heidi Heitkamp Mary (Heidi) Kathryn HeitkampCentrists, progressives rally around Harris pick for VP 70 former senators propose bipartisan caucus for incumbents Susan Collins set to play pivotal role in impeachment drama MORE (N.D.) – have said they will support Gorsuch. Both Democrats are up for reelection next year and hail from states that Trump won by big margins in November.

Republicans have threatened to change Senate rules if Democrats try to block the nomination by eliminating their ability to filibuster and confirming Gorsuch with a simple majority vote.

Pence's comments weren't the first time the vice president threw his support behind the so-called nuclear option. In February, he said Gorsuch would join the Supreme Court "one way or the other." Trump has also urged Senate Republicans to "go nuclear" if Democrats attempt to block the nomination.

The speech on Saturday marked the vice president's third consecutive weekend trip to promote Trump's agenda. The president's young administration has faced turmoil in recent weeks amid the failure of the GOP plan to repeal and replace ObamaCare and a series controversies and revelations surrounding congressional investigations into Russian election meddling.