Some of the issues the company faces are more about semantics, as they can use Skrulls but not the Super Skrulls, and The Watchers but not Uatu -- but there are some areas that hit harder. Annihilus -- a terrifying bug-like alien from the Negative Zone -- would make for a great and horrific foe in a future Marvel Cosmic movie, but unfortunately he is off limits. The same is true for the power duo that is the Silver Surfer and Galactus, and the Doctor Doom decedent Kang The Conqueror. There are certainly stories that can be told without all of these characters, but comic book fans will always miss their presence mixing in with other known heroes and villains.