June Foray, an actress of a thousand voices, who portrayed Rocky the flying squirrel and the fiendish spy Natasha Fatale on the wickedly satirical animated adventures of Rocky and Bullwinkle in the 1960s and myriad other animated creatures and characters on television and film, died on Wednesday in Los Angeles. She was 99.

Her niece Lauren Marems confirmed the death.

Ms. Foray began her remarkable 85-year career playing an elderly woman in a radio drama in 1929 at age 12. She portrayed scores of radio characters in the 1930s and ’40s. Over the next 60 years, she provided voices for animated shorts, feature films and television shows, as well as record albums, video games, even talking toys. Her last performance was as Rocky in a 2014 Rocky and Bullwinkle cartoon produced by DreamWorks Animation.

Often compared to Mel Blanc, the cartoon virtuoso who supplied the voices of Bugs Bunny, Daffy Duck and Porky Pig, Ms. Foray cackled, chirped, meowed and sometimes sang her way through nearly 300 animated productions, often playing several parts at once with quick shifts of accent, dialect and personality. Her work, unlike that of Mr. Blanc, was often uncredited, particularly in her early years.

But her output was prodigious. While she was not well known to the general public, the entertainment world called her the First Lady of Animated Voicing. At 94, she became the oldest person to win an Emmy, cited for her Mrs. Cauldron on “The Garfield Show,” and in 2013 she received an Emmy Governors Award.