It would appear Rune Factory 4 is selling rather well in North America. The game is suffering shortages at retail, and Xseed say they’re working hard to restock copies. On Facebook, Xseed wrote:

We’ve received quite a few inquiries asking about Rune Factory 4 since it’s been difficult to find in stores in North America. Don’t worry! It’s just been selling well beyond our expectations, so we’re working as quickly as possible to restock physical copies. We encourage you to periodically check back with retailers since they should be getting more in stock soon. Thanks for making Rune Factory 4 a major success, guys!

Meanwhile, over in Japan, Marvelous AQL are teasing a new Nintendo 3DS game by the developers of Rune Factory. More on this story as it develops.