Surgeons in Sweden have replaced the cancerous windpipe of a Maryland man with one made in a laboratory and seeded with the man’s cells.

The windpipe, or trachea, made from minuscule plastic fibers and covered in stem cells taken from the man’s bone marrow, was implanted in November. The patient, Christopher Lyles, 30, whose tracheal cancer had progressed to the point where it was considered inoperable, arrived home in Baltimore on Wednesday. It was the second procedure of its kind and the first for an American.

“I’m feeling good,” Mr. Lyles said in a telephone interview from his home, where he was playing with his 4-year-old daughter. “I’m just thankful for a second chance at life.” He said he hoped to resume his job, as an electrical engineer with the Department of Defense, as soon as he regained full strength.

“He went home in very good shape,” said Dr. Paolo Macchiarini, director of the Advanced Center for Translational Regenerative Medicine at the Karolinska Institute in Stockholm.