A man has been charged with murder after a woman was found dead with stab wounds in Melbourne's south-eastern suburbs.

The woman, in her 40s, was found at a Whitby Way property in Seaford at about 4.40pm on Tuesday.

Paramedics worked on the woman but were unable to save her.

A 44-year-old man was arrested at the scene and later charged with murder. He is expected to face Melbourne Magistrates' Court on Wednesday morning.

Police believe the two are known to each other.

Homicide squad detectives are at the site.