An unlikely coalition of lawmakers is plotting how to revise the nation’s marijuana laws during the 116th Congress — a mission that’s become much more viable in recent years as public support for legalizing cannabis shoots up and members introduce bills in higher numbers than ever before.

That legislation languished at the bottom of the hopper during the last Congress as GOP leaders remained steadfast in their opposition. But now advocates are optimistic that Democratic control of the House and mounting pressure to clean up the disparity between state and federal laws could propel some incremental changes through the Republican-controlled Senate — even if it will be a challenge.

At the top of the bipartisan wish list are bills to fix the banking, tax and legal gray areas that have emerged as more and more states set up marijuana dispensaries in open defiance of federal law.

Watch: Wait, there’s a Cannabis Caucus? Pot proponents on the Hill say it’s high time for serious policy debate