It was the tweet heard round the sex-worker world. At 6:12 p.m. on Oct. 29, Margaret Cho, the 46-year-old comedian, disturbed the Twittersphere with an economical 109 characters: “Sex work is simply work. For me it was honest work. I was a sex worker when I was young. It was hard but well paid. There’s no shame in it.”

What followed was a series of delighted tweets of support from current and former adult-industry workers, which Ms. Cho met with lots of XXXs and OOOs, as well as no shortage of derision from those less impressed with her revelation.

On the quiet Sunday that followed, Ms. Cho sat crossed-legged on the bed in her dark-wood-paneled room at the Maritime Hotel in Chelsea, wearing russet leggings and a black tank top, her high-density colored tattoos fanning up and out from her chest and down her arms. Her hair was cropped G.I.-short, and a glossy black wig splayed across the room’s narrow desk like a resting familiar.

In New York to promote her PsyCHO show at Town Hall on Nov. 11 and her new song and video “(I Want to) Kill My Rapist,” which will debut on Nov. 13 on perezhilton.com, Ms. Cho said she was surprised (pleasantly) by the largely supportive response to what she said has never been much of a secret. “I’ve never had shame about it,” she said. “I’ve been talking about it all along, but nobody cared.”