McDreamy 2.0?

In the wake of Patrick Dempsey’s surprise departure from Grey’s Anatomy, ABC’s still-durable medical soap is looking to add a major new male presence in Season 12, TVLine has learned exclusively.

According to fresh casting intel, Shonda Rhimes & Co. are searching for a “name” actor in his late 30s to late 40s to portray the series-regular role of a doctor. Among the requirements of said performer: He must be good-looking, charismatic and believable as a surgeon.

Rhimes acknowledged back in April that “the entire Grey’s Anatomy family” is entering “uncharted territory as we head into this new” post-Derek era, adding that, “The possibilities for what may come are endless. As Ellis Grey would say: the carousel never stops turning.”

So, which available actor should jump on the Grey Sloan carousel? Peruse our gallery of suggestions below, and then hit the comments with your own casting tips!