HOUSTON — Former Vice President Joe Biden was interrupted by a group of DREAMERS at the end of Thursday night’s Democratic debate.

Biden was being asked by moderator George Stephanopoulos to talk about any professional setback he’d experienced. “I never counted any professional setback I had as a setback,” Biden began.

The protesters then moved toward the stage. “We are DACA recipients,” the group yelled, before their chant became an indecipherable din.

“Defend DACA, Abolish ICE, Citizenship for all,” read two of the protesters t-shirts.

Security guards quickly escorted the noisy crew out, while most in the audience couldn’t make out the protesters’ cause. and Stephanopoulos restored Biden’s full time.

Rep. Joaquin Castro, whose twin brother Julian Castro was onstage, watched the whole thing from the audience and told The Post the protesters were saying, “We’re DACA, our lives are in danger.”

He said a couple of them made it just “barely” onstage. “They were talking about the limbo that they are living in and what’s at stake in their lives,” Castro added. “It lasted probably about 45 seconds. They walked a few steps and security asked them to come down and they did.”

Another witness, María Teresa Kumar, said the protesters weren’t trying to target Biden but made their move after debate moderators announced there’s only one more question left, figuring “this is my last shot.”

At least two of the three protesters made it on stage. Police stopped them in a dramatic moment and escorted them out peacefully without handcuffs, said Kumar, CEO of Voto Latino.

The Democrats’ Detroit debate was interrupted by protesters in the audience as well, with New York City Mayor Bill de Blasio targeted for his handling of Eric Garner’s death.