A study appearing in Annals of Internal Medicine links infection to prior oral sex partners, among other risks.

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Human Papilloma Virus, the highly prevalent sexually transmitted infection, is like Amtrak on Thanksgiving - it comes with a lot of baggage. We associate HPV with cervical cancer, but somewhere between 2008 and 2012, oropharyngeal cancer overtook cervical cancer as the most common HPV-associated malignancy.

We used to associate oropharyngeal cancer with smoking, but the epidemiology demonstrates that in the modern era oropharyngeal cancer is really driven by HPV.