NRL players and officials will be made to front the NSW Crime Commission as soon as Thursday as authorities ramp up their probe into alleged match-fixing of rugby league matches.

Detectives from the State Crime Command's Organised Crime Squad have launched Strike Force Nuralda to investigate betting patterns on at least three NRL games to determine whether any criminal offences have been committed.

Fairfax Media has been told interviews with people of interest will begin on Thursday, just a day before Brisbane and the Gold Coast open the NRL finals series at Suncorp Stadium. Police will immediately start questioning dozens of players and officials, although there is no suggestion that those summoned have committed any offence.

The development has the ability to derail the finals prospects of any side containing league identities viewed as persons of interest. While the investigation is expected to take months to complete, Wednesday's announcement that a strike force has been formed is a signal investigations will now begin in earnest.