Chaotic Confetti Cornea

This light-sheet microscopy image depicts a K14CreERT2-Confetti mouse cornea that received a severe epithelial debridement wound, spanning limbus-limbus to mimic limbal stem cell deficiency. In this instance, instead of a neat linear array of multi-colored spokes which typically develop in a normal cornea, a chaotic patchwork evolved eight weeks after injury. The image of the normal confetti cornea can be viewed here.

Image courtesy of Nick Di Girolamo and Mijeong Park, University of New South Wales, Sydney, Australia.

Do you have an image you’d like to see featured in The Ophthalmologist?