It’s do or die tonight in St. Louis for Donald J. Trump.

Because loose lips sink ships, at least for Republicans. For Hillary Clinton, not so much.

In 2005, speaking to one of the lesser Bushes, Trump made some horrible, totally indefensible comments about Nancy O’Dell (whoever she is). Suddenly it was a bigger story than 9/11, Pearl Harbor and the JFK assassination combined. This happens the same afternoon that it comes out that Hillary Clinton is for “open borders” and — nothing to see here folks, move along.

Open borders. Think about that one. In other words, an unending tidal wave of millions of Third World immigrants swarming across the border looking for handouts. In short order, it would be the end of the United States of America.

Hillary said open borders are her “dream.” Her dream, 320 million Americans’ nightmare.

Yet the Democrat candidate’s endorsement of an end to national sovereignty rates little more than a sidebar in any newspaper or website today.

Because Donald Trump used the “p” word. Somebody get the smelling salts.

Amazing. Do you recall what Bill Clinton told his galpal Gennifer Flowers about Hillary Clinton and the “p” word? Don’t worry if you’ve forgotten, Drudge has posted a link to the story.

Even more revealing, take a moment to Google Clinton, Vernon Jordan, Martha’s Vineyard and the “p” word. You will be directed to a fascinating story from Newsweek magazine in 1998. Believe it or not, Trump is not the first statesman to drop the “p” word while engaged in locker-room banter.

But don’t tell Sen. Kelly Ayotte. She went into the fetal position Friday afternoon almost before the story even finished moving across the A wire.

Ditto Paul Ryan and a host of other spineless RINOs.

And now every sob sister and every pajama boy on every failing broadsheet in the land is feigning shock, shock I say over what Donald Trump said on a tour bus on his way to a soap-opera taping. You want to know the biggest difference between Donald Trump and Bill Clinton? Trump took no for an answer.

It never fails. Whenever Trump closes in on Hillary in the polls, they drop another bomb on his head. Yes, it’s his own damn fault. But the media play every one of these handouts like it’s the second coming of Woodward and Bernstein.

Even before the story broke late Friday, the media already had their stories written about Hillary’s marvelous victory tonight in St. Louis. Now the moderators and the post-debate analysts don’t even have to fake objectivity. Why, this is going to be payback for that poor woman, Nancy What’s-Her-Name.

The Red Sox have a better chance of coming back against the Indians than Trump does of getting a fair shake in the Show-Me State. Much better.

Another of the damning WikiLeaks that can’t buy a thrill this weekend is when Hillary tells her paymasters at Goldman Sachs:

“Now, obviously, I’m kind of far removed (from the angst of the middle class) because of the life I’ve lived and the economic, you know, fortunes that my husband and I now enjoy.” But wait, I thought she was “dead broke” when she and her so-called husband left the White House in 2001.

And now it’s meet me in St. Louie, Louie. Donald J. Trump vs. Hillary Clinton, Martha Raddatz and Anderson Cooper.

Three on one is Democrat fun. Good luck tonight, Donald, and by the way, I repeat, who the hell is Nancy O’Dell?

Listen to Howie 3-7 p.m. on WRKO AM 680.