Injury set to rule Isco out of the Madrid derby LaLiga Santander - Real Madrid His chances of playing were slim beforehand

It was already unlikely that Isco would have featured in the line-up for Saturday's derby between Real Madrid and Atletico at the Estadio Wanda Metropolitano, but his slim chances have taken another hit as he ended Friday's training session early through injury.

The former Malaga player is now set to miss his third matchday squad list under Santiago Solari, after being excluded from the games against Melilla and Roma.

Solari hasn't counted on Isco since taking charge at the Estadio Santiago Bernabeu in November and he didn't even warm up during Real Madrid's game at the Camp Nou on Wednesday.

It has not been an easy time for the player under the Argentine and his situation was brought back into the headlines after he tweeted a response to Ruben de la Red on Thursday.