Newark, New Jersey (CNN) Twelve jurors began their deliberations Monday in the federal corruption trial of Sen. Bob Menendez and a wealthy ophthalmologist -- the outcome of which could determine the political future of the New Jersey Democrat.

"I am convinced that I will be declared not guilty, innocent of all charges," Menendez told reporters heading into court Monday morning.

The Justice Department's 18-count public corruption indictment accuses the senator of accepting over $600,000 in political contributions, free rides on a private jet, and a swanky hotel suite in Paris from Dr. Salomon Melgen.

In exchange, prosecutors say Menendez abused the power of his office by pressuring federal officials in the Obama administration and other career diplomats to help Melgen resolve a number of business disputes.

Jurors continued to hear closing arguments for several hours Monday before retiring to their room to determine the pair's fate.

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