A pedestrian died Saturday when she was run down in a crosswalk by a yellow cab on the Upper East Side, police said.

At about 2:45 p.m., the taxi, headed north on Madison, tried to make a left turn onto East 60th Street, said witnesses.

The cab then struck the woman, in her 60s. Police did not yet release her name.

“I heard screeching of the brakes,” said an employee of Barney’s, who declined to give her name. “People started screaming. I turned around and there was a woman on the floor. I called 911.”

Another witness said rescuers administered CPR to the woman seemingly without result.

She was declared dead at New York Hospital/Weill Cornell Medical Center.

The cab driver, weeping, stayed at the scene and spoke with police. He is not expected to be charged, police said.