Police searching for missing Hull University student Libby Squire have said they fear she may have “come to some harm”.

The comments came as Humberside Police released images of replicas of clothing the 21-year-old was wearing on the night she disappeared.

A replica of Ms Squire's outfit provided by Topshop – a black denim skirt, faux leather jacket and black trainers – has helped identify her in the CCTV footage used to piece together her movements on the night of Thursday 31 January.

Detective Superintendent Martin Smalley said: “While we do continue to be hopeful and we will always keep an open mind, Libby has been missing for 14 days now and we sadly have to consider she may have come to some harm.

“We are continuing to support Libby’s family through this incredibly difficult and distressing time. They are understandably distraught not knowing where their daughter and loved one is, and we will endeavour to give them the answers they desperately need.”

Libby Squire search: disappearance of 21-year-old university student Show all 18 1 /18 Libby Squire search: disappearance of 21-year-old university student Libby Squire search: disappearance of 21-year-old university student Police officers began searching after Hull university student, Libby Squire, went missing after a night out Getty Images Libby Squire search: disappearance of 21-year-old university student The 21-year-old was last seen on Thursday 31 January, 2019 PA Libby Squire search: disappearance of 21-year-old university student Officers have said Ms Squire was dropped off in a taxi near her home on Wellesley Avenue at 11.29pm on Thursday and was seen 10 minutes later on CCTV near a bench on Beverley Road, where a motorist stopped to offer her help PA Libby Squire search: disappearance of 21-year-old university student Libby's parents Lisa and Russ Ms Squire’s family said her disappearance is completely out of character and described her as a “very thoughtful and caring young woman who puts others before herself” PA Libby Squire search: disappearance of 21-year-old university student More than 200 volunteers joined 70 police and the Hull Coastguard Rescue Team searching the city for her PA Libby Squire search: disappearance of 21-year-old university student Welly Club on Beverley Road PA Libby Squire search: disappearance of 21-year-old university student Friends have said the student did not have her phone on her during the night PA Libby Squire search: disappearance of 21-year-old university student Her parents Lisa and Russ issued a statement thanking everyone who had helped in the search for their daughter, saying they had been “overwhelmed with people’s kindness and support”. They said: “Growing up, Libby was a really happy child, and she is extremely close to her family and her siblings.” PA Libby Squire search: disappearance of 21-year-old university student Officers urged people living in the area to check their gardens and outbuildings in case she had taken shelter PA Libby Squire search: disappearance of 21-year-old university student President of University of Hull Students' Union Osaro Otabo (left) and Vice-Chancellor of the university Professor Susan Lea as they address students and staff gathered in solidarity and support of student Libby PA Libby Squire search: disappearance of 21-year-old university student Police search in Newland near Hull PA Libby Squire search: disappearance of 21-year-old university student A police officer with a dog conducts a search on Wellesley Avenue PA Libby Squire search: disappearance of 21-year-old university student Police search the frozen Oak Road Pond Getty Images Libby Squire search: disappearance of 21-year-old university student Police search on the Beverley and Barmston Drain PA Libby Squire search: disappearance of 21-year-old university student Staff and students gather at the University of Hull in solidarity and support of student Libby Squire, who has been missing from her home in the city since early on Friday. PRESS ASSOCIATION Photo. Picture date: Tuesday February 5, 2019. See PA story POLICE Hull. Photo credit should read: Danny Lawson/PA Wire Danny Lawson PA Libby Squire search: disappearance of 21-year-old university student Police officers search drains near to the home of missing 21-year-old student Libby Squire Getty Images Libby Squire search: disappearance of 21-year-old university student Police search Oak Road Pond PA Libby Squire search: disappearance of 21-year-old university student Police search for missing 21-year-old student Libby Squire, on the Beverley and Barmston Drain PA

CCTV images released on Wednesday showed Ms Squire walking towards The Welly nightclub in Beverley Road on the night she disappeared. The philosophy student appeared unsteady on her feet.

She is believed to have taken a taxi home from the nightclub after she was refused entry. The 21-year-old was dropped off in a taxi near her home at 11.29pm and was then seen 10 minutes later near a bench back on Beverley Road. She is believed to have been in this area until about 12.09am on Friday.

Previously released CCTV footage shows a man getting in and out of a car around the time of her disappearance, close to where the missing student was last seen.

Clothes similar to the ones worn by Libby Squire on the night she disappeared (PA)

“More work is now taking place behind the scenes rather than in public view, however this does not mean the investigation is slowing or coming to an end, it is exactly the opposite and is very much active and ongoing,” said DS Smalley.

Pawel Relowicz, 24, was arrested last Wednesday on suspicion of abduction.

Earlier this week police announced that Mr Relowicz had been charged with unrelated offenses: three counts of burglary, voyerism and outraging public decency reported between December 2017 and January this year.

Screengrab from CCTV footage issued of a woman (circled) believed to be Libby Squire (PA)

Speaking through a Polish interpreter, he pleaded not guilty to all charges at Hull Magistrates Court on Monday. He is due to appear at Hull Crown Court on 11 March.

On Wednesday evening, family and friends of Ms Squire held a vigil in her hometown of West Wycombe in Buckinghamshire.

About 300 people attended the two-hour service at St Paul’s church, where candles were lit and prayers were said.

Her parents also released new family photos on Wednesday and said in a statement: “Libby is a much loved big sister to her three younger siblings. They all really look up to her and she always expects them to behave.

“Libby has a big heart. She is always happy and having fun. She laughs a lot. She is a real family person, and loves spending time at home with them.”