Western Reserve Playhouse will opens its 2018 season with Neil Simon’s “Lost in Yonkers,” which runs Jan. 26 and 27 and Feb. 2 through 10.

Simon is known as one of America’s great comic playwrights, and this memory play is set in Yonkers in 1942. Bella is 35, mentally challenged and living at home with her mother, stern Grandma Kurnitz.

As the play opens, ne’er-do-well son Eddie is financially strapped and taking to the road as a salesman. He deposits his two young sons on Grandma’s doorstep — where they are left to contend with her, Bella and her secret romance, and with Louie, her brother, a small-time hoodlum — in a strange new world called Yonkers.

Keith Stevens directs, and the cast stars young actors Robbie Rush and James Patrick, along with seasoned professionals Shani Ferry and August Scarpelli, as well as OCTA recipients Beth Gaiser and Jay Hill. Rounding out the ensemble is award-winning local luminary Harriet DeVeto.

Show times are Fridays and Saturdays at 8 p.m. and Sunday at 2 p.m. Tickets are $16 for adults and $14 for seniors and students. Western Reserve Playhouse is located at 3326 Everett Road, in Bath.

To reserve tickets, visit www.westernreserveplayhouse.org.