NASHVILLE, Tenn. -- Tennessee Titans quarterback Marcus Mariota, who suffered an ankle injury in Sunday's game, was a full participant at practice Wednesday and is expected to play against the Green Bay Packers.

Mariota injured his ankle on the third or fourth series of the Titans' loss to the San Diego Chargers on Sunday, coach Mike Mularkey said.

Despite suffering the injury, Mariota was still able to run for a nifty, 14-yard touchdown.

"It wasn't a big deal," Mariota said.

Mariota, who missed four games with two different knee injuries as a rookie in 2015, took a long time to get to the podium after Sunday's game at San Diego's Qualcomm Stadium, and he wore sneakers with his suit.

He ran well at practice Wednesday and showed no signs of the issue.

Mularkey and Titans general manager Jon Robinson have made it a priority to protect Mariota, the No. 2 pick in the 2015 draft. The blocking scheme was changed under new offensive line coach Russ Grimm, and Mariota's offseason training focused on building strength in muscle groups that enhance leg stability.

Free-agent center Ben Jones and rookie right tackle Jack Conklin have helped solidify protection, though Conklin was limited in practice Wednesday due to an elbow injury. The Titans endured a season-ending injury to right guard Chance Warmack, who has been replaced by Josh Kline. Starting left guard Quinton Spain missed the last two games with a knee injury, but should return Sunday after Brian Schwenke subbed for him.

Though Mariota was able to participate fully on Wednesday, the Titans were without running backs DeMarco Murray, who is resting a toe injury, and Derrick Henry, who suffered a calf injury during Sunday's warmups.

"It's probably not going to go away like you'd like it to," Mularkey said of Murray's injury. "Especially with the plants he does and the cutting. It is getting better, but it's still painful."

Henry has "looked better than I was anticipating," Mularkey said.