The general election began in earnest Wednesday, and likely Democratic nominee Hillary Clinton is starting with a big lead against presumptive Republican nominee Donald Trump.

That’s according to a new CNN/ORC national poll released Wednesday, the day after Trump all but clinched the GOP race with a primary victory in Indiana that forced Ted Cruz to drop out. Clinton lost Indiana to her Democratic rival Bernie Sanders, who has vowed to continue his campaign to the convention, but Clinton’s delegate lead has become insurmountable.

The survey found Clinton starting the general election with a 13-point advantage against Trump. Both candidates, however, are viewed unfavorably. Clinton is underwater by just one point (48% view her favorably, compared to 49% unfavorably. But Trump is in a deeper hole, with only 39% viewing him favorably and 57% unfavorably.

Clinton’s 54%-41% advantage over Trump is her largest since July. Her supporters are split over their reasons for backing her, with 51% saying they are voting for her to oppose Trump. On the Republican side, 57% of his supporters back him to prevent another Clinton from entering the White House.

The survey of 1,001 Americans, conducted April 28-May 1, has a margin of error of plus or minus 3%.

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