In the year following the 2004 tsunami, the Indonesian city of Meulaboh received eight neonatal incubators from international relief organizations. Several years later, when an MIT fellow named Timothy Prestero visited the local hospital, all eight were out of order, the victim of power surges and tropical humidity, along with the hospital staff's inability to read the English repair manual.

Mr. Prestero and the organization he cofounded, Design That Matters, had been working for several...