(CNN) Americans are scarfing down more and more low-calorie sweeteners, and researchers are raising some concerns.

The consumption of low-calorie sweeteners jumped a whopping 200% among children and 54% among adults from 1999 to 2012, according to a study published in the Journal of the Academy of Nutrition and Dietetics on Tuesday.

"We were somewhat surprised," said Allison Sylvetsky, assistant professor at the Milken Institute School of Public Health at George Washington University, who was lead author of the study.

"While we anticipated an increase, the magnitude of the increase was much larger than we had anticipated, particularly in kids," she said. "It is not surprising that low-calorie sweetener consumption continues to increase, though. ... There has been a lot of pressure put on the food and beverage industry to reformulate, which has led to more lower-sugar, low-calorie sweetener containing products appearing on the market."

Low-calorie sweeteners, also referred to as artificial sweeteners , are sweet-tasting compounds that provide few or no calories when consumed, Sylvetsky said.

Such sweeteners are often used to replace added sugars, such as sucrose and high-fructose corn syrup, in foods and beverages. They can be found in such products as diet sodas, powdered drink mixes, sugar-free ice cream and light yogurts.

Americans are sweet on sweeteners

For the study, researchers analyzed data on low-calorie sweetener consumption, in the form of food, drinks and packets, among 16,986 children and adults in the United States from 2009 to 2012. The data came from the National Health and Nutrition Examination Survey , which included self-reports on food and drink intake.

The researchers compared their findings with a previous data analysis that explored low-calorie sweetener consumption from 1999 to 2008 . That previous analysis also relied on data from the National Health and Nutrition Examination Survey.

The researchers found that about 25% of children and about 41% of adults consumed low-calorie sweeteners from 2009 to 2012 in the United States. In comparison, the previous analysis showed that only 8.7% of children and about 30% of adults consumed some type of low-calorie sweetener from 1999 to 2008.

Beverages, such as diet sodas, accounted for the majority of low-calorie sweetener consumption in both children and adults, the researchers found.

Photos: How many calories are in your sweetener? Photos: How many calories are in your sweetener? The sweet truth – Natural and artificial sweeteners are in more food products than you might expect. Find out how many calories are in your favorite sweetener and see which ones have the most nutritional bang for your buck. Hide Caption 1 of 10 Photos: How many calories are in your sweetener? White sugar – What most people consider sugar is refined granulated sugar , or white sugar, which is derived from sugarcane or sugar beets. Common in foods, it has less nutrients than other natural sweeteners due to a refining process. Calories per tablespoon: 48. Hide Caption 2 of 10 Photos: How many calories are in your sweetener? Brown sugar – Brown sugar is created when molasses is added to sugar crystals. It has higher calcium and potassium levels than its white counterpart. The darker the sugar, the more molasses is present. Calories per tablespoon: 51. Hide Caption 3 of 10 Photos: How many calories are in your sweetener? Molasses – Molasses is a byproduct when sugarcane and sugar beets are refined. It is often used in baked goods, and is a rock star when it comes to nutrition with 1,464 mg of potassium, 205 mg of calcium and 242 mg of magnesium -- the highest of all the sweeteners. Calories per tablespoon: 58. Hide Caption 4 of 10 Photos: How many calories are in your sweetener? Maple syrup – Maple syrup is made from the sap of maple trees, though the artificial varieties are often just a combination of water and sugars. Nutritional perks of authentic syrups include calcium and potassium. Calories per tablespoon: 52. Hide Caption 5 of 10 Photos: How many calories are in your sweetener? Honey – Honey is produced by bees and has the most calories out of all the sweeteners on our list. The Mayo Clinic recommends that people who have bee-related allergies avoid honey, and it shouldn't be given to children younger than 12 months. Calories per tablespoon: 64. Hide Caption 6 of 10 Photos: How many calories are in your sweetener? Corn Syrup – Corn syrup is a sweetener made from corn starch that is commonly used in drinks and packaged foods. It comes in light, dark and high-fructose syrups (the dark syrup contains the most nutrients). Mayo Clinic says there is a lack of evidence on the possible dangers of the controversial high-fructose variety. Calories per tablespoon: Light (62), dark (57), high-fructose (53). Hide Caption 7 of 10 Photos: How many calories are in your sweetener? Agave nectar – A more exotic sweetener, agave nectar is created from the agave plant that is native to southern and western United States and parts of South America. It contains fewer carbs than most other sweeteners and contains vitamin C. Calories per tablespoon: 63. Hide Caption 8 of 10 Photos: How many calories are in your sweetener? Stevia – The leaves from stevia plants are used for medicinal purposes and as a sugar-free sweetener. It is reported to be much sweeter than white sugar, but isn't approved by the FDA . Nausea is a possible side effect . Calories per tablespoon: 0. Hide Caption 9 of 10 Photos: How many calories are in your sweetener? Artificial sweeteners – Equal and NutraSweet are FDA-approved artificial sweeteners made from aspartame (two amino acids put together). Another artificial sweetener, Splenda , is sucralose-based and is created from chemically processed sugar. According to researchers , one possible risk of digesting these products is that it can confuse your body, making it harder to process real sugars as a result. Calories per tablespoon: 0. Hide Caption 10 of 10

This significant rise in low-calorie sweetener consumption may be a result of more sweeteners emerging in the food supply, recent obesity-prevention campaigns or the increased prevalence of diabetes, the researchers suggested.

"It's an interesting study, particularly the differentiation between drinks versus other items. It's a very important distinction," said Sacha Uelmen, director of nutrition for the American Diabetes Association, who was not involved in the study.

She added that low-calorie sweeteners are mentioned in the association's 2017 Standards of Medical Care as having the potential to reduce overall calorie and carbohydrate intake if they are substituted for caloric sweeteners and consumed in moderation (PDF).

JUST WATCHED How diet soda confuses your body Replay More Videos ... MUST WATCH How diet soda confuses your body 01:52

As the new study revealed a high prevalence of low-calorie sweeteners, the researchers called for more trials examining potential health effects of sweetener exposure in children and adults.

Rachel Hicks, a spokeswoman for the American Beverage Association, issued a statement on behalf of the association assuring consumers that low-calorie sweeteners are safe.

"Decades of scientific research, as well as regulatory agencies around the globe, have repeatedly reaffirmed the safety of low- and no-calorie sweeteners as part of the diet. And the science is clear that because they have few, if any, calories these sweeteners can be an effective tool for weight loss or as part of a weight management plan," the association said in the statement.

A diet soda debate

Experts have long debated whether sugar-free and diet products, which often include low-calorie sweeteners , are beneficial for weight control.

JUST WATCHED New study links diet soda to belly fat Replay More Videos ... MUST WATCH New study links diet soda to belly fat 03:36

The latest jab thrown in the fight comes from a paper published in the journal PLOS Medicine last week. It suggests that there is a lack of evidence to support the role of artificially sweetened beverages , such as diet sodas, in preventing weight gain.

Though low-calorie sweeteners are believed to be safe in terms of toxicology, "what is less clear is how low-calorie sweeteners may influence appetite, weight management and risk of chronic diseases such as diabetes," Sylvetsky said.

"There is tremendous public health significance in investigating whether low-calorie sweeteners are helpful or harmful for weight management and chronic disease prevention," she said. "This is particularly important to study in children, as early life exposure may influence future taste preferences and dietary patterns."

Join the conversation See the latest news and share your comments with CNN Health on Facebook and Twitter.

Uelmen, of the American Diabetes Association, agrees.

"I would love to see more research on the effect of low-calorie sweeteners, in children especially and also adults," she said. "There is a lot of skepticism in the public around diet drinks and these sweeteners; however, there is also a lot of demand and need for options."