“God bless you, ma’am,” Cruz responded.

While O’Rourke used Twitter to offer Cruz some sympathy, the Republican found himself the target of some taunts on the platform after a Politico article revealed snapshots of him apparently looking at an image of O’Rourke on a flight.

Cruz also took some hits from conservative columnist Bret Stephens, who in a New York Times Op-Ed piece referred to him as a “serpent covered in Vaseline.”