WASHINGTON — President Obama is traveling to the shadow of Wall Street on Thursday to counter what he calls “the furious efforts of industry lobbyists” trying to weaken or kill new financial regulations that he says are needed to stave off a second Great Depression.

As the Senate debates how to rewrite rules governing the financial industry, Mr. Obama will lay out the elements he insists must be in any legislation to get his signature. Among them are more consumer protections, limits on the size of banks and the risks they can take, reforms on executive compensation and greater transparency for controversial securities known as derivatives.

In flying to New York City, the president wants to confront the financial industry more directly through a sharp speech just a few minutes’ subway ride from Wall Street, and with some of its leading corporate titans in the audience. After castigating their “failure of responsibility” in recent years, he intends to call on them to stop resisting tighter regulation through the army of lobbyists now staked out on Capitol Hill.

“I am sure that many of those lobbyists work for some of you,” Mr. Obama plans to say, according to excerpts of the speech provided by the White House for release on Thursday morning. “But I am here today because I want to urge you to join us, instead of fighting us in this effort. I am here because I believe that these reforms are, in the end, not only in the best interest of our country, but in the best interest of our financial sector.”