“Run,” a new romantic comedy with twists to flatter a pretzel festival, follows former lovers who are escaping their lives. And it arrives when most of us can’t even escape our own homes. To watch the show now is to entertain an impossible fantasy. No, it’s not receiving a text from your college ex, not upending your life to meet said ex, not the subsequent hotel room sex, though “Run” does include all that.

It’s the running itself — by plane and train and pleasure boat and hitchhiked ride from a shy taxidermist.

“The idea of being able to go anywhere, the idea of being able to be close to people by choice, I wonder how that will color people’s experience of the show,” Merritt Wever, who plays the female lead in “Run,” said.

“Run,” which introduces the first of its seven episodes on April 12, opens with Wever’s Ruby, neck-deep in ennui in a Ralphs parking lot. Her phone vibrates with a one-word text: “RUN.” Moments later, Ruby is en route to the airport, on her way to meet Billy (Domhnall Gleeson), the former boyfriend she hasn’t seen in 17 years.