The games mean something now.

The 2019 NFL season gets into full gear on Sunday with a day-long slate featuring some rivalries, budding stars and 32 teams vying to win Super Bowl 54.

Here are our favorite games in Week 1:

Kansas City Chiefs at Jacksonville Jaguars (1 p.m. ET, CBS)

One of the NFL’s most entertaining offenses meets one of the NFL’s most dangerous defenses. What can reigning MVP Patrick Mahomes do for an encore? After lighting up the league in his first full season, which ended in a crushing overtime loss to the Patriots in the AFC Championship, Mahomes gets back on the field to start writing a new ending.

The Jaguars’ defense had what many considered to be a down year last season, with “Sacksonville” failing to live up to its name in terms of getting to the quarterback. But the Jaguars still had a top-5 defense and figure to be in for a bounce-back season. Plus, Nick Foles has taken over for Blake Bortles at quarterback, perhaps keeping the defense on the sidelines for a bit longer.

Atlanta Falcons at Minnesota Vikings (1 p.m. ET, FOX)

Both teams missed out on the playoffs last year after making it to the NFC divisional round in 2017, but both are aiming to be back this season. The Vikings hope Year 2 for Kirk Cousins will be what they hoped it would be when they signed him to a three-year, $84 million contract. Last season included plenty of growing pains and a lack of explosiveness for Cousins, who has a pair of 1,000-yard receivers at his disposal in Stefon Diggs and Adam Thielen.

Matt Ryan, meanwhile, hopes to be operating behind an improved offensive line. The Falcons drafted a pair of linemen in the first round of April’s draft and added two more starters through free agency, trying to give Ryan enough time to find weapons like Julio Jones. But it could be tough sledding against the Vikings’ stout defense.

Pittsburgh Steelers at New England Patriots (8:20 p.m. ET, NBC)

Two of the AFC’s perennial powerhouses will see how life is without big pieces of their offenses. For the defending Super Bowl champion Patriots, there is no more Rob Gronkowski after the tight end retired by going out on top. But there is still 42-year-old quarterback Tom Brady, entering his 20th season, beginning his quest to win a seventh ring.

For the Steelers, Antonio Brown and Le’Veon Bell are gone — though Bell wasn’t really there last year, either — leaving Ben Roethlisberger to navigate the AFC North with a younger group of playmakers. It will also mark another trip for Mike Tomlin to Gillette Stadium, where the Steelers coach has complained about headsets malfunctioning in the past.

NFL Week 1 Schedule:

Thursday, Sept. 5

Green Bay Packers at Chicago Bears – [Packers win, 10-3]

Sunday, Sept. 8 (all times Eastern)

Buffalo Bills at New York Jets – 1:00 p.m. (CBS)

New York Giants at Dallas Cowboys – 1:00 p.m. (FOX)

Los Angeles Rams at Carolina Panthers – 1:00 p.m. (FOX)

Atlanta Falcons at Minnesota Vikings – 1:00 p.m. (FOX)

Kansas City Chiefs at Jacksonville Jaguars – 1:00 p.m. (CBS)

Washington Redskins at Philadelphia Eagles – 1:00 p.m. (FOX)

Baltimore Ravens at Miami Dolphins – 1:00 p.m. (CBS)

Tennessee Titans at Cleveland Browns – 1:00 p.m. (CBS)

Indianapolis Colts at San Diego Chargers – 4:05 p.m. (CBS)

Cincinnati Bengals at Seattle Seahawks – 4:05 p.m. (CBS)

San Francisco 49ers at Tampa Bay Buccaneers – 4:25 p.m. (FOX)

New York Giants at Dallas Cowboys – 4:25 p.m. (FOX)

Detroit Lions at Arizona Cardinals – 4:25 p.m. (FOX)

Monday, Sept. 9. (all times Eastern)

Houston Texans at New Orleans Saints – 7:00 p.m. (ESPN)

Denver Broncos at Oakland Raiders – 10:20 p.m. (ESPN)