Vice President Joe Biden told supporters that Republicans would "put y'all back in chains," during a campaign speech Tuesday in Danville, Va.

VICE PRESIDENT JOE BIDEN: They’ve said it. Every Republican’s voted for it. Look at what they value and look at their budget and what they’re proposing. Romney wants to let the—he said in the first 100 days, he’s going to let the big banks once again write their own rules–unchain Wall Street. They’re going to put y’all back in chains. He’s said he’s going to do nothing about stopping the practice of outsourcing…

Biden was introduced at the campaign event by Center for American Progress Action Fund president Tom Perriello, who called Biden "the conscience of our nation's capital."

The Romney campaign reacted strongly to the remarks, calling them "not acceptable" in a statement released shortly after Biden's campaign speech.

"The comments made by the vice president of the United States are not acceptable in our political discourse and demonstrate yet again that the Obama campaign will say and do anything to win this election," spokeswoman Andrea Saul said in the statement. "President Obama should tell the American people whether he agrees with Joe Biden’s comments."

But Obama deputy campaign manager Stephanie Cutter the campaign has "no problem with those comments," in an interview with Andrea Mitchell.

An Obama campaign official later told CNN's John King that Biden's comments were "not helpful."

Update 7:35 p.m.: This post has been updated to combine updates throughout the day into one post.