More than 100 donkeys and 50 camels sourced from the Northern Territory and South Australia are set to go under the hammer this weekend in Echuca, in northern Victoria.

Interest in donkeys has been steadily growing among cattle and sheep producers, since research suggested they make effective guardian animals.

A trial by Livestock Health and Pest Authorities at Holbrook, in New South Wales, found donkeys can be used to protect sheep and cattle from wild dog attacks.

The agent organising the auction, Andrew Wilson, says he's expecting more than 1000 people to attend.

"The interest has been mind blowing," he said.

"It has not stopped, the other day I had 92 messages over five hours.

"Every time I talk on the phone I miss three calls.

"You can't get a hotel in Echuca or the surrounding areas.

"People are coming from Western Australia, South Australia, Queensland - if everyone turns up it will be a nightmare!"

Mr Wilson says he's expecting prices to reach upwards of $350 per animal.

"To be fair, it's hard to pick what's a good looking donkey but the best ones could make up $800 or $900."

While Mr Wilson hopes the auction could become more regular event, he says transport costs could be a limiting factor.

"We'd struggle to send a truck up there just to pick them up and bring them back.

"It needs to be tied in a with a bigger job."

Federal Government estimates suggest there are as many as five million donkeys roaming across remote Australia, and about 300,00 feral camels.