A jihadi bride once dubbed 'France's most wanted woman' who fled to join ISIS after her husband attacked a Paris deli has died in an airstrike in Syria, it is claimed.

Hayat Boumeddiene, whose husband Amedy Coulibaly killed four hostages and a policewoman at a kosher supermarket in the French capital, is said to have been killed in the town of Baghouz - the terror group's final Syrian stronghold.

Boumeddiene was initially hunted by police as an accomplice to Coulibaly's attack, days after the Charlie Hebdo massacre in 2015, before fleeing to join ISIS.

But she was killed in a strike last week that hit a bunker known as the 'French House,' according to another jihadi bride who interviewed after evacuating from Baghouz.

Dorothee Macquere also revealed that her husband, notorious jihadist Jean-Michel Clain, was killed in a mortar strike over the weekend.

He had already been struggling with wounds suffered in an earlier airstrike that killed his jihadi brother, Fabien Clain, one of Europe's most wanted who claimed ISIS responsibility for the horrific November 2015 attacks in Paris which killed 130 innocents.

It comes as more than 10,000 starving women, children and suspected fighters have been evacuated from Baghouz in the last two weeks amid a brutal siege.

Hayat Boumeddiene (left with Amedy Coulibaly and right, with a gun in military clothing) fled France following her husband's terror attack in Paris in January 2015

'France's most wanted': Maquere said Boumeddiene (pictured) had 'started a new life' and remarried. She said she didn't have any children

Dorothee Maquere, wife of French jihadist Jean-Michel Clain, sits with four of her five children at a screening area after fleeing Baghouz, where she said Boumeddiene was slain by an SDF shell

Maquere, wife of French jihadist Jean-Michel Clain, is pictured at a screening area after fleeing the besieged town of Baghouz

Maquere had fled from Baghouz where ISIS are making their last stand against the US-backed Syrian Democratic Forces (SDF).

Maquere was one of hundreds of people who over the past two days streamed out of the diseased and starved village of Baghouz, where ISIS are making their last stand against the US-backed Syrian Democratic Forces (SDF).

The latest wave of evacuations brings the final defeat of ISIS by the Kurdish-led SDF one step closer - a milestone in the devastating four-year campaign to defeat the group's so-called 'caliphate' that once covered a vast territory straddling both Syria and Iraq.

Fabien Clain - brother of Jean-Michel and brother-in-law to Maquere - he was wanted by Interpol after he claimed IS responsibility for the November 2015 Paris attacks

Maquere, who is also French, said the situation inside Baghouz was a 'horror film,' saying there is a 'massacre' inside, with constant shooting.

People had to lay flat to avoid the crossfire, she said, adding that there were 'no more homes, we live underground in tunnels and tents.'

She said her seven-year-old daughter was killed and her other daughter wounded by an explosion two weeks ago. Two other sons were killed earlier in a mortar attack and Syrian government fire.

Speaking at a desert reception area where SDF fighters were screening the evacuees, the 38-year-old said she does not want to go back to France, which is part of the US-led coalition fighting IS.

'I want France to leave me alone. They killed my husband, my children. ... I want nothing from them. They did already enough harm. I want them to leave me with my children,' she said, cradling her two-week old son, one of her five surviving children.

Her account, if verified, closes a chapter on a number of French militants who were connected to attacks in past years in and around Paris and who then made their way to IS's 'caliphate' and finally, as it crumbled, to this tiny village on the Euphrates River near the Iraqi border.

Hayat Boumeddiene appeared in a propaganda video holding an AK-47 with other members of ISIS

Amedy Coulibaly donned Middle Eastern attire as he sat before a black IS flag beside an assault rifle ahead of his January 2015 attack on the kosher deli in Paris

Coulibaly and Boumeddiene pose in this undated photograph released in the wake of his shocking terror attack on a kosher deli in January 2015

Her husband, Jean-Michel Clain, who Maquere said wrote religious anthems for IS, was seriously wounded in a February 20 airstrike in Baghouz that killed his brother, Fabien, one of Europe's most wanted IS members.

The US-led coalition announced Fabien's death several days after the strike.

The two brothers joined IS together and Fabien went on to become the group's voice in France.

Fabien's voice was on an IS recording claiming responsibility for the worst terrorist violence in France's modern history - a series of bombings and shootings in Paris in November 2015 that killed 130 people.

Jean-Michel held on for a little over a week after the airstrike. Maquere said she tried to treat him, but his feet were torn apart and one side of his body was crushed. 'He suffered,' she said.

'There was no hospital.' He was killed on Sunday when a mortar struck, causing him a direct head wound, she said.

Boumeddiene was killed in a separate airstrike in Baghouz about a week ago, Maquere said.

Maquere sits with her children after fleeing the last bastion at Baghouz were terrorists are fighting to the death against the US-backed SDF

A little girl gazes up at an SDF fighter who holds his assault rifle fast as his comrades work to screen those fleeing ISIS

On their knees: A Bosnian man suspected of being an ISIS fighter kneels before SDF men as he surrenders from Baghouz on Friday

A diagram showing the last remaining ISIS territory in Syria in the eastern province of Deir Ezzor, where U.S.-backed coalition forces have launched a bid to push them out

Boumeddiene was the widow of Amedy Coulibaly, a Frenchman who attacked a kosher supermarket in Paris in January 2015, days after two other militants - brothers Cherif and Said Kouachi- gunned down the staff of the weekly satirical magazine Charlie Hebdo.

Coulibaly killed four people in the supermarket before French police stormed in and killed him. The Kouachi brothers were killed by police in a separate raid. All told, their attacks left 17 people dead.

Investigators then focused on finding Boumeddiene, who was believed to be pregnant at the time. But she had already fled to Syria.

Soon after, IS published what it said was an interview with her in French and English, in which she called on women to be patient and make life easier for their husbands.

Maquere said Boumeddiene had 'started a new life' and remarried. She said she didn't have any children.

Pounds of explosives rained down on the last remaining stronghold as the US-backed forces seek to drive out the extremists from the land

Fragments of hot metal burst from an explosion on the settlement as the extremists prepare to go to the grave for their futile cause

The French-Moroccan evacuee said Boumeddiene had told her she had no idea about plans for the 2015 attack in Paris or her husband's plans.

Boumeddiene's evolution was documented in photos widely distributed in French media after her disappearance, from vacation pictures of her in a bikini to images of her holding a crossbow while wearing an all-encompassing black niqab.

The last known image of her was from airport surveillance video in Istanbul, going through passport control.

Tuesday's exodus came three days after US-backed forces resumed their push on IS militants holed up in Baghouz.

The assault had been slowed the previous week to allow thousands of civilians, including IS family members, to be evacuated from the tiny pocket of territory. As many as 10,000 people who had been squeezed into the eroding patch of land, are estimated to have streamed out - an enormous number that stunned the SDF.

Asked about the situation inside Baghouz, a Russian woman who came out with her three children responded in broken Arabic: 'Fear.' She said her husband had died earlier.

Smoke billows from the town as shelling resumed on Monday as the SDF say that battle 'will soon be over'

A Kurdish warrior loads a strap of bullets into his machine gun magazine as he prepares to lay down rounds on Sunday

A Kurdish SDF fighter scans the battlefield as his forces prepare to make a brave push into the tunnel network of the jihadists

Another woman in her mid-20s, who identified herself as Reem from the central Syrian province of Hama, said she was waiting for her husband to come out of an IS-controlled jail. He has been there for months after killing an IS member in retaliation 'for his baby daughter being killed in an airstrike,' she said.

'I haven't seen him since and don't know where he is,' Reem said, adding that she asked repeatedly for his whereabouts before she eventually decided to leave.

The evacuees said the bombing has been intense in recent days. One woman said she saw a man hit by a missile as she was fleeing from one tent to another.

Earlier on Tuesday, SDF spokesman Mustafa Bali tweeted that about 3,000 people came out of Baghouz on Monday. They left through a humanitarian corridor established by the Kurdish-led forces for those who want to leave or surrender.

Since February 20, more than 10,000 people have left the IS pocket and black-robed women with children in the backs of trucks could be seen passing through the corridor and heading into the desert. They were then whisked off to a camp for displaced people to the north, while suspected IS fighters were moved to detention facilities.

Bali said a large number among those who left Monday were IS fighters who 'surrendered to our forces.'

It was unclear how many IS militants and civilians remained inside, but the number is now likely in the hundreds.