Alcohol (Ethanol) interacts with GAMMA-HYDROXYBUTYRATE (GHB) Concomitant use may increase the risk of serious CNS and respiratory depression (3678,102834). Ethanol may also inhibit the clearance of GHB (3682,102831). Research also shows that concomitant use can increase the risk of other adverse events, including gastrointestinal disturbances , hypotension, and decreased oxygen saturation (93831).

Amphetamines interacts with GAMMA-HYDROXYBUTYRATE (GHB) Amphetamines are drugs that can speed up your nervous system. GHB can slow down your nervous system. Taking GHB along with amphetamines can lead to serious side effects.

Haloperidol (Haldol) interacts with GAMMA-HYDROXYBUTYRATE (GHB) GHB can affect the brain. Haloperidol (Haldol) can also affect the brain. Taking haloperidol (Haldol) along with GHB might cause serious side effects.

Medications for mental conditions (Antipsychotic drugs) interacts with GAMMA-HYDROXYBUTYRATE (GHB) GHB can affect the brain. Medications for mental conditions also affect the brain. Taking GHB along with medications for mental conditions might increase the effects and serious side effects of GHB. Do not take GHB if you are taking medications for a mental condition.

Some of these medications include fluphenazine (Permitil, Prolixin), haloperidol (Haldol), chlorpromazine (Thorazine), prochlorperazine (Compazine), thioridazine (Mellaril), trifluoperazine (Stelazine), and others.

Medications used to prevent seizures (Anticonvulsants) interacts with GAMMA-HYDROXYBUTYRATE (GHB) Medications used to prevent seizures affect chemicals in the brain. GHB is changed in the body to one of these brain chemicals called GABA. Taking GHB along with medications used to prevent seizures might decrease the effects of GHB.

Some medications used to prevent seizures include phenobarbital, primidone (Mysoline), valproic acid (Depakene), gabapentin (Neurontin), carbamazepine (Tegretol), phenytoin (Dilantin), and others.

Muscle relaxants interacts with GAMMA-HYDROXYBUTYRATE (GHB) Muscle relaxants can cause drowsiness. GHB can also cause drowsiness. Taking GHB along with muscle relaxants might cause too much drowsiness and serious side effects. Do not take GHB if you are taking muscle relaxants.

Some of these muscle relaxants include carisoprodol (Soma), pipecuronium (Arduan), orphenadrine (Banflex, Disipal), cyclobenzaprine, gallamine (Flaxedil), atracurium (Tracrium), pancuronium (Pavulon), succinylcholine (Anectine), and others.

Naloxone (Narcan) interacts with GAMMA-HYDROXYBUTYRATE (GHB) GHB can affect the brain. Taking naloxone (Narcan) along with GHB might decrease the effects of GHB on the brain.

Ritonavir (Norvir) interacts with GAMMA-HYDROXYBUTYRATE (GHB) Ritonavir (Norvir) and saquinavir (Fortovase, Invirase) are commonly used together for HIV/AIDS. Taking both of these medications plus GHB might decrease how quickly the body gets rid of GHB. This could cause serious side effects.

Saquinavir (Fortovase, Invirase) interacts with GAMMA-HYDROXYBUTYRATE (GHB) Saquinavir (Fortovase, Invirase) and ritonavir (Norvir) are commonly used together for HIV/AIDS. Taking both these medications plus GHB might decrease how fast the body gets rid of GHB. This could cause serious side effects.

Sedative medications (Benzodiazepines) interacts with GAMMA-HYDROXYBUTYRATE (GHB) GHB (BD) might cause sleepiness and drowsiness. Medications that cause sleepiness and drowsiness are called sedatives. Taking GHB along with sedative medications might cause serious side effects. Do not take GHB if you are taking sedative medications.

Some of these sedative medications include clonazepam (Klonopin), diazepam (Valium), lorazepam (Ativan), and others.