Lloyd Blankfein, the chief executive of US investment bank Goldman Sachs, has suggested that the UK should hold a second referendum on Brexit in his latest foray into the political arena on Twitter.

Mr Blankfein is an infrequent tweeter, having posted only 26 times, but has had a dig at Brexit - either directly or indirectly - on four occasions.

In his latest comments, Mr Blankfein said: “Here in UK, lots of hand-wringing from CEOs over #Brexit. Better sense of the tough and risky road ahead.

“Reluctant to say, but many wish for a confirming vote on a decision so monumental and irreversible. So much at stake, why not make sure consensus still there?”

His comments come as the City’s calls for swift clarity on the terms of Brexit to prevent the triggering of relocation plans intensifies.