John Hastings has been ruled out of the Australia's Caribbean tri-series with the West Indies and South Africa after ankle surgery on the weekend.

Fellow Victorian pace bowler Scott Boland has been drafted into the Australian squad for the Qantas Tour of the West Indies.

Cricket Australia Sports Science and Sports Medicine Manager Alex Kountouris said the need for surgery to remove bone spurs became apparent after Hastings returned from the Indian Premier League.

Hastings suffered the injury during training before the Kolkata Knight Riders' clash with the Mumbai Indians at Eden Gardens on April 13.

"John experienced pain in his left ankle during his recent stint in the IPL and had scans upon returning home which have confirmed early stage bone stress of his fibula bone near his ankle," Kountouris said.

"While laid off with this injury we have taken this opportunity to undertake arthrosporic surgery to remove bone spurs in his left ankle which have been causing him concern for some time and were possibly contributing to the cause of the bone stress.

"John had this surgery over the weekend and now requires a period of rest to resolve the bone stress and recover from surgery before he will resume bowling."

Quick Single: How The Duke roared back to life

Hastings had started the IPL tournament in terrific fashion, claiming 2-6 inside three over in the Knight Riders' emphatic nine-wicket opening win over Delhi Daredevils.

Hastings then played through pain in Kolkata's six-wicket loss to Mumbai, finishing with 0-31 from four overs, after which he flew back to Australia.

It's a blow for Hastings, who suffered three shoulder injuries last summer but rebounded to play one-day and T20 cricket for Australia.

Hastings had dislocated his left shoulder three times prior to Christmas, all in a freak training mishaps, but opted not to undergo surgery to continue playing and push on for the World Twenty20 and IPL.

The shoulder injury is on Hasting's non-dominant arm and does not prevent him from bowling. It is understood he is currently focussed on getting the ankle right and the shoulder is seen as a lower priority.

Hastings, who stands at an impressive 195cm, has been colossal in white-ball cricket since returning in the one-day international series against England last September.

A career-best 3-21 in the deciding match at Old Trafford proved his class at international level, but he was initially overlooked for the Victoria Bitter ODI series against India last summer.

The 30-year-old earned a call-up – initially just for one match – when the national selectors decided to rest fellow allrounder Mitchell Marsh, and the Victorian hasn't looked back.

Hastings played the remaining four matches of the series, claimed four wickets at the MCG – a new personal-best – and was frugal in a run-heavy series.

He backed it up with a superb display in New Zealand, bowling tight and scoring a vital 48no in concert with Marsh to guide Australia home in Wellington.

Hastings takes career-best figures

Australia begin the triangular series against fellow tourists South Africa in Guyana on June 6 before locking horns with the hosts four days later at the same venue.

The round robin tournament sees each team play three matches against each opponent, with the top two teams advancing to the final on June 26 in Barbados.

Australia squad for the Qantas Tour of the West Indies: Steve Smith (c), David Warner (vc), George Bailey, Scott Bolland, Nathan Coulter-Nile, James Faulkner, Aaron Finch, Josh Hazlewood, Travis Head, Usman Khawaja, Nathan Lyon, Mitchell Marsh, Glenn Maxwell, Mitchell Starc, Matthew Wade, Adam Zampa