Another bike-by shooting has struck Los Angeles — this time nearly claiming the life of a well-loved philanthropist as he sat parked in his Rolls-Royce on Sunset Boulevard in Hollywood.

Four years after high-power publicist Ronni Chasen was randomly gunned down by a bike-riding transient — also on Sunset Boulevard — cops in Los Angeles were still looking Saturday night for the lone bicyclist gunman who fired into the face and chest of millionaire Kameron Segal, 48.

“This is still a very active, ongoing investigation,” LAPD spokeswoman Jane Kim told The Post. Segal remains hospitalized in critical but stable condition, she said.

The shooter’s motive remained unclear, she said, adding, “We are exploring all possibilities.”

Asked of the gunman’s mode of transportation, the police spokeswoman noted, “It’s not that unusual that he was on a bike — in California, a lot of people ride bikes.”

It was just before 9 p.m. Friday when Segal was shot through his open window as he sat in a parking lot in his new, black and silver luxury car.

Witnesses told cops that the two-wheeled gunman, described as in his 30s, fired twice.

A friend of Segal told local TV station NBC4 that the entrepreneur — who owns multiple apartment complexes in the area — had been waiting for a business associate and planned to drive to a meeting in downtown LA.

Segal was well-known for his charitable acts, including his donation of six months’ free rent to a homeless woman after she lost her job just this past Christmas, local TV station KCAL9 reported.

Chasen, 64, was murdered during a botched robbery in November 2010 in Beverly Hills, four miles from the scene of Friday’s shooting.

She had been stopped at a light in her Mercedes-Benz coupe when troubled felon Harold Martin Smith, 43, pedaled over and attempted to rob her, police said.

She apparently resisted or ignored the gunman — and he opened fire, police said.

The publicist’s Mercedes careened for a quarter-mile before crashing into a light pole.

Days later, Smith committed suicide as police came to his door to question him — shooting himself in the head using the same gun that killed Chasen.

There were two other bike-by shootings in California in the past three months, according to press accounts. One pedaling shooter fired into a house in Fresno County on Jan. 2, and the other shot a rival in the legs as the victim sat in a parked car in San Bernadino in November.

New York hasn’t seen a bike-by since 2011, when a cyclist fatally opened fire into the left eye of an aspiring rapper outside the Jackie Robinson Houses in East Harlem.