The Weinstein brothers first came to prominence with Miramax in 1989, the year they helped to activate the indie-film boom with “Sex, Lies and Videotape.” They sold Miramax to Disney in 1993 and left in 2005 to form the Weinstein Company. They unsuccessfully dabbled in side businesses, including a fashion label, but eventually found their film footing with releases like “Inglourious Basterds.”

Lately they have hit a dry spell. Although they have a fast-growing television division, the Weinsteins have not had a mainstream hit at the North American box office since 2013, when “Lee Daniels’ The Butler” took in $116.6 million.

Image David Glasser, the president of the Weinstein Company, convened a staff meeting on Thursday night. Credit... David Walter Banks for The New York Times

So far this year, the Weinstein Company, a boutique studio that specializes in sophisticated, small-budget dramas like the 2011 Oscar winner “The King’s Speech,” has released six films, which have taken in a combined $123 million at the domestic box office. (The biggest hit has been “Wind River,” a well-reviewed murder mystery that has collected about $33 million.) Last year, the Weinsteins had seven films, with combined ticket sales of just $65 million.

To compare, major studios like Warner Bros. and the Walt Disney Company generally take in $1 billion to $2.5 billion annually at the domestic box office.

The Weinstein Company has also found itself sidelined at film festivals, where Mr. Weinstein has long shopped for movies to release, helping to discover auteurs like Quentin Tarantino and Steven Soderbergh. For years at the Sundance Film Festival, for instance, his wallet was the only one that mattered to agents, who would track his team relentlessly. Netflix and Amazon dominate now.