Other journeys were to cities with frequent and far cheaper commercial flights from Washington or to places where Price had family or owned property, raising questions about whether all his travels were for business purposes.

He offered Thursday to reimburse taxpayers for about $52,000. It was unclear how Price arrived at that number, but in a Fox News interview that day he defended his move, calling his repayment “unprecedented” and saying the trips were “within budget.”

“All of these trips were official business,” Price said on “Special Report with Bret Baier.” “All of them were approved by the normal processes that every other administration has gone through prior to the trip, not after. But we’ve heard the concerns.”

It was a swift fall for Price, a six-term congressman who had represented the north Atlanta suburbs who long said running the Health and Human Services Department was his dream job. A third-generation doctor, Price built his political career around health care policy.

Price held the job for less than eight months, following a contentious and drawn-out Senate confirmation process during which Democrats alleged Price had toed ethical lines with his health stock trades given his powerful position on Capitol Hill.

He was initially sold as the face of Trump's core campaign pledge to scrap the Affordable Care Act. Eventually, though, other senior officials such as Vice President Mike Pence and budget chief Mick Mulvaney took on more prominent public roles as Republicans worked to replace the 2010 law. Price instead worked behind the scenes to loosen some of Obamacare's restrictions.

Price becomes the first Cabinet member to exit the Trump administration since the president was sworn into office in January.

Names for potential replacements began swirling before his ouster. Axios reported that Food and Drug Administration Commissioner Scott Gottlieb, former Louisiana Gov. Bobby Jindal and Medicare administrator Seema Verma were among the figures being floated as potential successors.