Wall Street’s favorite regulator is on his way out.

Michael Piwowar, a Republican commissioner at the Securities and Exchange Commission, announced Monday that he intends to step down by July — ending a five-year run as a reliably anti-regulatory Beltway voice.

Piwowar’s absence leaves a split commission, with two Democrats serving among the four remaining commissioners — thus slowing SEC Chairman Jay Clayton’s de-regulatory agenda.

An Obama-appointed regulator, Piwowar built a pro-business legacy that pushed back against some stricter regulations and disclosures enshrined in the Dodd-Frank financial regulatory law.

“He was a vigorous advocate of free markets and the economic growth that can follow from that,” said Norm Champ, former director at the SEC’s investment management division.

In a statement, Piwowar said he would leave by July 7.

He was staunchly against rules that measured the pay gap between CEOs and workers at public companies.

In a dissenting 2015 opinion, he called the disclosures a “sad example of surrendering the commission’s agenda to politically connected special interests.”