The principals in addition to Mr. Scialla and his brother, both early Goldman retirees, are: the company’s co-founder, Morad Fareed, a former executive of the Starwood Hotels and Resorts Worldwide and a member of the Clinton Global Initiative; and the chief operating officer, Renato Termale. Delos has already installed 16 WELLness features in several dozen hotel rooms at the MGM Grand Hotel in Las Vegas. The rooms command a 40 percent premium and have, Mr. Fareed said, recovered the cost of installing the amenities.

The company is converting an estate in Montecito, Calif., into a Delos oasis, as well as retrofitting a CBRE office in Los Angeles, ostensibly to make for happier, healthier, more productive employees. And in a philanthropic collaboration with the musician Will.i.am, it plans to Delos-ize a public school in Boyle Heights in East Los Angeles.

The 13th Street loft has already attracted a stream of celebrities curious enough about Delos’s potential impact on public health to take a tour, including former President Bill Clinton; Eric Schmidt, Google’s chairman; Dr. Mehmet Oz, the TV personality; and Deepak Chopra, the self-improvement guru.

This type of “smart” home construction doesn’t come cheap. But Mr. Scialla foresees the amenities’ becoming as cost-effective and accepted as green technology and LEED certification. Delos is not, he emphasized, intended to enhance only the health of the 1 percent. But for now they are its main beneficiaries, because it is they who can best afford to indulge.

The five apartments on East 11th Street are in an 1897 Italianate building with a terra-cotta facade, auspicious acanthus carvings, and a history as a dress factory and most recently a parking garage. Prices range from $15.5 million, for each of the three floor-through lofts, to $50 million for the duplex penthouse, whose 22-by-8-foot picture window frames the historic Grace Church.

The largest apartment, at 10,000 square feet, is the so-called mansion: it is listed at $45 million and, if the buyer is so inclined, can be accompanied by its own potentially two-space parking garage, with a separate price tag of $1 million. The buyer of the penthouse is also entitled to buy the garage: first come first served. (Drivers of Hummers or Escalades should count on just a single spot.)