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Weight loss. It’s a topic that is discussed frequently and to various sentiments depending upon where one is with the struggle to overcome the battle. We have a variety of methods attempted such as diet supplements, healthy eating, portion control, exercise regiments, and various surgeries to name a few.

What if there were another option that is not only free but sometimes also a paid option? Think about that for a moment. Free help in an attempt to lose weight and in some cases even better getting paid to do so!

Here are five clinical trials here in the United States that are currently recruiting. Please note that each clinical trial may have its own requirements such as co-existing conditions, the region of the U.S. seeking participants, etc. but direct links to each clinical study are being provided so all information is available to you the reader.

1. SMART Weight Loss Management, Northwestern University

The overall objective of this study is to use an innovative experimental approach, the SMART (Sequential Multiple Assignment Randomized Trial), to determine the best way to sequence the delivery of mHealth tools and traditional treatment components in a stepped program of obesity treatments. The SMART approach is a highly efficient strategy for identifying and constructing efficacious adaptive interventions: it accommodates sequential decision-making based on the participant’s response to early weight loss treatment components. The proposed treatment package begins with the least expensive components, and for participants identified as treatment non-responders, provides sequential step-up of additional treatment components. By sequentially delivering treatment components based on participant response, SMART permits achievement of the target outcome, weight loss, with least resource consumption and participant burden.

Study ID: NCT02997943

Contact:

Laura Martindale, MS 312-503-1395 laura.martindale@northwestern.edu Study Link: https://clinicaltrials.gov/ct2/show/NCT02997943 2. A Trial of the Ideal Protein System Versus Low Fat Diet for Weight Loss, Tulane University This study will examine whether, compared to a standard, low-fat, calorie-restricted diet intervention, the clinic-supported Ideal Protein weight loss method will result in greater weight loss and improvement in cardiometabolic risk factors over 3 months among obese adults with cardiovascular disease (CVD) risk factors. Study ID: NCT03515889 Contact: Lydia Bazzano, MD, PhD 504-988-7323 lbazzano@tulane.edu Study Link: https://clinicaltrials.gov/ct2/show/NCT03515889 3. Using the Hunt Motivational Scale to Aid in Weight Loss and Weight Maintenance, Penn Medicine Princeton Health In this study, we plan to determine the efficacy of the Hunt Motivational Scale as a tool for weight loss compared to standard of care in the Penn Medicine Princeton Health weight management program.

Study ID: NCT03530553

Contact:

Rameck Hunt, MD 908-930-8257 rahunt@princetonhcs.org

Study Link: https://clinicaltrials.gov/ct2/show/NCT03530553

4. Sleep During Weight Loss and Weight Loss Maintenance, Dartmouth-Hitchcock Medical Center

The purpose of the study is to examine the changes in sleep during weight loss and weight loss management. The research staff will also obtain data on sleep disturbances, insomnia symptoms, risk of sleep apnea, circadian preferences, weight loss self-efficacy, emotional eating, executive functioning, loneliness, and social isolation, and patients’ beliefs about how sleep might impact their weight control or vice versa.

Study ID: NCT03774563

Contact:

Hannah G Haskell, BA Courtney Stevens, PhD 603-650-7251 hannahg.haskell@hitchcock.org courtney.j.stevens@dartmouth.edu

Study Link: https://clinicaltrials.gov/ct2/show/NCT03774563

5. Apollo OverStitch for Bariatric Surgery Revision After Weight Loss Failure, University of California, San Francisco

Morbid obesity and its associated metabolic diseases are on the rise in the United States. Currently, the best treatment for obesity is bariatric surgery where both Roux-en-Y gastric bypass and sleeve gastrectomy offer substantial weight loss. Unfortunately, 20% of patients who undergo bariatric surgery fail to lose enough weight defined as less than 50% of excess body weight loss or regain of weight. For those patients who fail to lose weight after bariatric surgery and have failed maximal medical therapy and diet supervision, the treatment is re-operation and revision. Re-operation of the abdomen carries significant postoperative morbidity and mortality. The investigators propose to use the Apollo OverStitch endoscopic suturing device that has already been approved by the FDA as an option for bariatric surgery revision without having to re-operate on the patient. The investigators believe that the endoscopic technique may be able to provide weight loss without having to re-operate on the patient.

Study ID: NCT01871896

Contact:

Matthew Y Lin, MD 415-476-0972 Matthew.Lin@ucsfmedctr.org

Study Link: https://clinicaltrials.gov/ct2/show/NCT01871896

We hope this information has been useful and have a great day! While we are slowly growing this site, if any other resource information is challenging to locate online please feel free to comment below as we will add it to the list of planned topics to post and/or investigate. This site is for you the reader!

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