California Rep. Darrell Issa (R), who used to be the chairman of the House’s investigative panel, may not be returning to Washington in a Hillary Clinton presidency.

If Democrats make substantial gains in the House, Issa and other veteran Republican lawmakers may find themselves on the losing end of the ballot box. Other GOP incumbents endangered include fellow California Rep. Jeff Denham, Florida Rep. John Mica, New Jersey Rep. Scott Garrett, Illinois Rep. Bob Dold and Colorado Rep. Mike Coffman.

In fact, the Cook Report’s latest ratings show 16 tossup House seats currently in Republican hands, and just two tossups in the Democratic column. Democrats need 30 seats to recapture the House majority, which is an uphill battle given the small number of overall seats in play.

Nonetheless, the House GOP majority is likely to shrink tonight, according to strategists on both sides of the aisle. We’ll be reporting some key House results in this space.

For more on which way the House will blow, read Karoun Demirjian’s congressional campaign story throughout the night.

And our in-house handicapper, Stuart Rothenberg, never bought into the hype that the House was in play. See his columns here.