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South Dakota’s coronavirus cases have begun to soar after its governor steadfastly refused to mandate a quarantine.

The number of confirmed cases in the state has risen from 129 to 988 since April 1 — when Gov. Kristi Noem criticized the “draconian measures” of social distancing to stop the spread of the virus in her state.

Noem had criticized the quarantine idea as “herd mentality, not leadership” during a news conference, adding, “South Dakota is not New York.”

The state is now home to one of the largest single clusters of coronavirus outbreaks, with 300 workers at a ­pork processing plant infected with the deadly bug, according to the Washington Post.

The factory, Smithfield Foods, accounts for 5 percent of the country’s pork production and announced it will be forced to close on Sunday.

“The closure of this facility, combined with a growing list of other protein plants that have shuttered across our industry, is pushing our country perilously close to the edge in terms of our meat supply,” Kenneth M. Sullivan, Smithfield’s president and CEO, said in a statement.

The Republican governor continues to resist a shutdown even as calls for such policies mount. The South Dakota State Medical Association penned a letter to Noem on April 3 urging her to institute a mandatory quarantine.

“A stay-at-home order would give our health professionals the necessary time and resources to manage this pandemic,” the group wrote on its website. “We may soon be facing the challenges and hardships being seen in New York and other cities if a shelter in place order is not issued immediately.”

South Dakota is among five rural states, all led by Republican governors, still resisting quarantine measures, including Arkansas, Iowa, Nebraska and North Dakota.

Iowa Gov. Kim Reynolds on Friday, April 3, cited the potential impact on residents’ mental health among a variety of factors in her resistance to a state lockdown.

“We are a connected community. There’s just that side of it as well,” Reynolds said. “In addition to suicides and domestic abuse, there are a lot of downsides to it as well.”

Noem did not immediately respond to a request for comment, but defended her stance to the Washington Post on Monday as cases mounted.

“The people themselves are primarily responsible for their safety,” she said. “They are the ones that are entrusted with expansive freedoms.”

Noem has closed schools and recommended that businesses allow employees to work from home and touted those measures during a briefing Tuesday.

“What we’re doing each and every day by getting up and using personal responsibility and taking actions at the local and state level — it is working,” she said.