Ted Cruz dropped out of the presidential race. After a year of denial, the race looks all but over — and Donald Trump will almost certainly be the Republican nominee.

For Twitter, these types of situations are a time for jokes. On Tuesday night, pundits and political watchers around the country lived up to the calling.

Some put a twist on Trump's nickname for Cruz, Lyin' Ted:

Others mocked Cruz's decision to pick a running mate in a desperate bid to revive his campaign:

So Carly Fiorina joined the campaign just in time to lay everyone off? — Kevin Robillard (@PoliticoKevin) May 4, 2016

I have the same odds of becoming Vice President that Carly Fiorina does — Dylan Matthews (@dylanmatt) May 4, 2016

A few referenced Cruz's secret past as the Zodiac killer:

I wonder what he's going to do next. pic.twitter.com/n1mrpBFZ8h — Sam Stryker (@sbstryker) May 4, 2016

In fairness, Ted Cruz did well for a known serial killer. — German Lopez (@germanrlopez) May 4, 2016

Many just felt disappointment:

Best, deepest Republican field in recent memory....wiped out one-by-one by the host of Celebrity Apprentice. — David Rutz (@DavidRutz) May 4, 2016

Shouldn't #TedCruz have been forced to carry his unviable campaign to term? — Full Frontal (@FullFrontalSamB) May 4, 2016

Unbelievable. I trusted Cruz when he said he'd win in November. Turns out he was Lyin' Ted after all. — Dan Diamond (@ddiamond) May 4, 2016

Yet for some, the news was a relief:

On the upside, I don't have to defend Ted Fucking Cruz any longer. — Rick Wilson (@TheRickWilson) May 4, 2016

Goodbye, Ted Cruz:

Ted Cruz ends campaign by accidentally hitting, elbowing his wife in the face pic.twitter.com/epO1tzKgTT — Jon Swaine (@jonswaine) May 4, 2016

Watch: Donald Trump on Ted Cruz