Nonpartisan election handicapper Larry Sabato has moved the rating for Alabama's special Senate election in favor of Democrats in the wake of sexual misconduct allegations against GOP nominee Roy Moore.

Sabato, who leads the University of Virginia's Crystal Ball, has changed the race from a toss-up as national Republicans pull their support and call on Moore to step aside.

Moore is set to square off against Democratic nominee Doug Jones on Dec. 12 in the race to replace Attorney General Jeff Sessions Jefferson (Jeff) Beauregard SessionsTrump's policies on refugees are as simple as ABCs Ocasio-Cortez, Velázquez call for convention to decide Puerto Rico status White House officials voted by show of hands on 2018 family separations: report MORE.

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Ahead of the GOP primary in August, Sabato had rated the race safe Republican. After the September runoff when Moore defeated Sen. Luther Strange Luther Johnson StrangeSessions hits back at Trump days ahead of Alabama Senate runoff The biggest political upsets of the decade State 'certificate of need' laws need to go MORE, he changed it to likely Republican.

"The GOP may find a way out of this mess, but the party — thanks to Roy Moore — is on the verge of blowing what was once a sure thing," Sabato tweeted about the ratings change.

We can't believe we're doing this, but at least for now AL-SEN--that's ALABAMA--Leans D (Doug Jones). The GOP may find a way out of this mess, but the party--thanks to Roy Moore--is on the verge of blowing what was once a sure thing. More tomorrow in the Crystal Ball. — Larry Sabato (@LarrySabato) November 15, 2017

Moore has denied the allegations that he initiated a sexual encounter with a 14-year-old girl when he was 32 and said he has never met a woman who says he sexually assaulted her when she was 16. He has said he's going to remain in the race, despite mounting pressure to drop out.

Some Republicans have floated the prospect of a write-in campaign and others have considered expulsion from the Senate if Moore wins.

National Democrats are growing cautiously optimistic about the race, though they remain reluctant to invest in it, arguing that Jones wouldn't benefit from being associated with Washington.

Some recent polls indicate that Jones has closed the gap with Moore, and others show him with a major lead. A poll from the Senate GOP's campaign arm released Wednesday shows Moore down by 12 points.