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Its possible, regular use of cannabis can cause changes in the brain:

Cannabis use also makes one less likely to develop or maintain proper coping skills for problems.

Long-term heavy cannabis use in healthy individuals is associated with smaller cerebellar white-matter volume similar to that observed in schizophrenia. Reduced volumes were even more pronounced in patients with schizophrenia who use cannabis. Cannabis use may alter the course of brain maturational processes associated with schizophrenia. http://journals.cambridge.org/action/displayAbstra...

Our findings indicate long-term cannabis use is hazardous to the white matter of the developing brain. Delaying the age at which regular use begins may minimize the severity of microstructural impairment. - http://brain.oxfordjournals.org/content/135/7/2245...

Teens who routinely smoke marijuana risk a long-term drop in their IQ - http://news.yahoo.com/teen-pot-linked-later-declin...

Informants also reported noticing more cognitive problems for persistent cannabis users. Impairment was concentrated among adolescent-onset cannabis users, with more persistent use associated with greater decline. Further, cessation of cannabis use did not fully restore neuropsychological functioning among adolescent-onset cannabis users. - http://www.pnas.org/content/early/2012/08/22/12068...

These results provide new evidence of exposure-

related structural abnormalities in the hippocampus

and amygdala in long-term heavy cannabis users and

corroborate similar findings in the animal literature. These

findings indicate that heavy daily cannabis use across protracted

periods exerts harmful effects on brain tissue and

mental health. - http://www.truecompassion.org/PDFS/Health%20and%20...

Despite relatively brief exposure, adolescent

cannabis users relative to their age-matched counterparts

demonstrated similar memory deficits to those reported in

adult long-term heavy users. The results indicate that

cannabis adversely affects the developing brain and

reinforce concerns regarding the impact of early exposure. - http://www.acceptandchange.com/wp-content/uploads/...