Brisbane’s north is the region in Queensland most affected by coronavirus as the state sits poised to pass 500 cases.

The state government confirmed another 50 cases on Thursday, taking the total to 493.

The Metro North Public Health Unit is managing 144 cases - almost 30 per cent of Queensland’s COVID-19 cases.

The Metro South region, comprising southern Brisbane suburbs, Logan, Redlands and the Scenic Rim, has the second highest number of cases with 123.

The Gold Coast has recorded 91 and Sunshine Coast 56.

The overwhelming majority of cases are concentrated in south-east corner, with health services in the Darling Downs (17), West Moreton (17) and Wide Bay (12) also treating cases.

North Queensland and regional areas are also affected.

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The Cairns region has 12 cases, Townsville has 11 and Central Queensland and Mackay have five each.

Queensland chief health officer Jeannette Young (centre), Queensland Premier Annastacia Palaszczuk (left) and Health Minister Steven Miles. File image. Credit: Dan Peled / AAP

The state’s north west, south west, central west, Cape York and Torres Strait have not recorded a case.

Two Queenslanders have died, including a 68-year-old man from Toowoomba on Wednesday.

He became Australia’s ninth coronavirus victim.

Coronavirus health signage at the Brisbane domestic airport terminal. Another 50 people in Queensland have been confirmed as having the disease on Thursday. Credit: Darren England / AAP

A 77-year-old woman from the Sunshine Coast died in Sydney earlier this month.

She was the fourth person in Australia to die from the disease.

Queensland has the third highest number of cases across the country, behind NSW (1219) and Victoria (520).