These findings extend prior research showing a negative relationship between psychedelic use and intimate partner violence, and highlight the potential role of emotion regulation in this association.

Males reporting any experience using lysergic acid diethylamide and/or psilocybin mushrooms had decreased odds of perpetrating physical violence against their current partner (odds ratio=0.42, p <0.05). Furthermore, our analyses revealed that male psychedelic users reported better emotion regulation when compared to males with no history of psychedelic use. Better emotion regulation mediated the relationship between psychedelic use and lower perpetration of intimate partner violence. This relationship did not extend to females within our sample.

We surveyed 1266 community members aged 16–70 (mean age=22.78, standard deviation = 7.71) using an online questionnaire that queried substance use, emotional regulation, and intimate partner violence. Respondents were coded as psychedelic users if they reported one or more instance of using lysergic acid diethylamide and/or psilocybin mushrooms in their lifetime.

The present study examined the association between lifetime psychedelic use and intimate partner violence among a community sample of men and women. The study also tested the extent to which the associations were mediated by improved emotion regulation.

Recent evidence suggests that psychedelic use predicts reduced perpetration of intimate partner violence among men involved in the criminal justice system. However, the extent to which this association generalizes to community samples has not been examined, and potential mechanisms underlying this association have not been directly explored.

References

Adamson, S, Metzner, R ( 1988 ) The nature of the MDMA experience and its role in healing, psychotherapy, and spiritual practice . Revision 10: 59 – 72 .

Google Scholar

Aldao, A, Nolen-Hoeksema, S, Schweizer, S ( 2010 ) Emotion-regulation strategies across psychopathology: A meta-analytic review . Clin Psychol Rev 30: 217 – 237 .

Google Scholar Medline | ISI

Allen, JP, Litten, RZ, Fertig, JB. ( 1997 ) A review of research on the Alcohol Use Disorders Identification Test (AUDIT) . Alcohol Clin Exp Res 21: 613 – 619 .

Google Scholar Medline | ISI

American Psychiatric Association ( 2013 ) Diagnostic and Statistical Manual of Mental Disorders. 5th ed. Washington, DC : American Psychiatric Publishing .

Google Scholar

Bey, T, Patel, A ( 2007 ) Phencyclidine intoxication and adverse effects: A clinical and pharmacological review of an illicit drug . Cal J Emerg Med 8: 9 – 14 .

Google Scholar Medline

Boles, SM, Miotto, K ( 2003 ) Substance abuse and violence: A review of the literature . Aggress Violent Behav 8: 155 – 174 .

Google Scholar ISI

Brandt, CP, Zvolensky, MJ, Bonn-Miller, MO ( 2012 ) Distress tolerance, emotion dysregulation, and anxiety and depressive symptoms among HIV+ individuals . Cognit Ther Res 37: 446 – 455 .

Google Scholar

Carhart-Harris, RL, Bolstridge, M, Rucker, J. ( 2016 ) Psilocybin with psychological support for treatment-resistant depression: An open-label feasibility study . Lancet Psychiatry 3: 619 – 627 .

Google Scholar Medline | ISI

Carod-Artal, FJ ( 2015 ) Hallucinogenic drugs in pre-Columbian Mesoamerican cultures . Neurlogia 30: 42 – 49 .

Google Scholar Medline

Chan, KL, Straus, MA, Brownridge, DA. ( 2008 ) Prevalence of dating partner violence and suicidal ideation among male and female university students worldwide . J Midwifery Womens Health 53: 529 – 537 .

Google Scholar Medline | ISI

Chandler, RK, Fletcher, BW, Volkow, ND ( 2009 ) Treating drug abuse and addiction in the criminal justice system: Improving public health and safety . JAMA 301: 183 – 190

Google Scholar Medline | ISI

Coker, AL, Davis, KE, Arias, I. ( 2001 ) Physical and mental health effects of intimate partner violence for men and women . Am J Prev Med 24: 260 – 268 .

Google Scholar

Ernst, AA, Weiss, SJ, Enright-Smith, S. ( 2008 ) Perpetrators of intimate partner violence use significantly more methamphetamine, cocaine, and alcohol than victims: A report by victims . Am J Emerg Med 26: 592 – 596 .

Google Scholar Medline | ISI

Fadiman, J ( 2011 ) The Psychedelic Explorer’s Guide: Safe, Therapeutic, and Sacred Journeys. 1st ed . Maine : Park Street Press .

Google Scholar

Feingold, A, Kerr, DC, Capaldi, DM ( 2008 ) Associations of substance use problems with intimate partner violence for at-risk men in long-term relationships . J Fam Psychol 22: 429 – 438 .

Google Scholar Medline | ISI

Foran, HM, O’Leary, KD ( 2008 ) Alcohol and intimate partner violence: A meta-analytic review . Clin Psychol Rev 28: 1222 – 1234 .

Google Scholar Medline | ISI

Gallimore, AR, Strassman, RJ ( 2016 ) A model for the application of target-controlled intravenous infusion for a prolonged immersive DMT psychedelic experience . Front Pharmacol 7: 211 .

Google Scholar Medline | ISI

Gasser, P, Kirchner, K, Passie, T ( 2014 ) LSD-assisted psychotherapy for anxiety associated with a life-threatening disease: A qualitative study of acute and sustained subjective effects . J Psychopharmacol 29: 57 – 68 .

Google Scholar SAGE Journals

Graham-Kevan, N, Archer, J ( 2003 ) Intimate terrorism and common couple violence. A test of Johnson’s predictions in four British samples . J Interpers Violence 18: 1247 – 1270 .

Google Scholar SAGE Journals | ISI

Gratz, KL, Roemer, L ( 2004 ) Multidimensional assessment of emotion regulation and dysregulation: Development, factor structure, and initial validation of the difficulties in emotion regulation scale . J Psychopathol Behav Assess 26: 41 – 54 .

Google Scholar ISI

Gratz, KL, Paulson, A, Jakupcak, M. ( 2009 ) Exploring the relationship between childhood maltreatment and intimate partner abuse: Gender differences in the mediating role of emotion dysregulation . Violence Vict 24: 68 – 82 .

Google Scholar Medline | ISI

Griffiths, RR, Johnson, MW, Carducci, MA. ( 2016 ) Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial . J Psychopharmacol 30: 1181 – 1197 .

Google Scholar SAGE Journals | ISI

Grob, CS, Danforth, AL, Chopra, GS. ( 2011 ) Pilot study of psilocybin treatment for anxiety in patients with advanced-stage cancer . Arch Gen Psychiatry 68: 71 – 78 .

Google Scholar Medline

Hartogsohn, I ( 2016 ) Set and setting, psychedelics and the placebo response: An extra-pharmacological perspective on psychopharmacology . J Psychopharmacol 30: 1259 – 1267 .

Google Scholar SAGE Journals | ISI

Hayes, SC, Strosahl, KD, Wilson, KG ( 1999 ) Acceptance and Commitment Therapy: An Experiential Approach to Behavior Change. New York : Guilford Press .

Google Scholar

Hayes, SC ( 2004 ) Acceptance and Commitment Therapy, Relational Frame Theory, and the third wave of behavioral and cognitive therapies . Behav Ther 35: 639 – 665 .

Google Scholar ISI

Hayes, AF ( 2013 ) Introduction to Mediation, Moderation, and Conditional Process Analysis: A Regression-Based Approach. New York, NY : The Guilford Press .

Google Scholar

Hendricks, PS, Clark, CB, Johnson, MW. ( 2014 ) Hallucinogen use predicts reduced recidivism among substance-involved offenders under community corrections supervision . J Psychopharmacol 28: 62 – 66 .

Google Scholar SAGE Journals | ISI

Hendricks, PS, Thorne, CB, Clark, CB. ( 2015 ) Classic psychedelic use is associated with reduced psychological distress and suicidality in the United States population . J Psychopharmacol 29: 280 – 288 .

Google Scholar SAGE Journals | ISI

Hendricks, PS, Crawford, MS, Cropsey, KL. ( 2018 ) The relationships of classic psychedelic use with criminal behavior in the United States adult population . J Psychopharmacol. 32: 37 – 48 .

Google Scholar SAGE Journals | ISI

Henning, K, Renauer, B, Holdford, R ( 2006 ) Victims or offender? Heterogeneity among women convicted of intimate partner abuse . J Fam Violence 21: 351 – 368 .

Google Scholar ISI

Hoaken, PN, Stewart, SH ( 2003 ) Drugs of abuse and the elicitation of human aggressive behavior . Addict Behav 28(9): 1533 – 1554 .

Google Scholar Medline | ISI

Hyde, JS, Mezulis, AH, Abramson, LY ( 2008 ) The ABCs of depression: Integrating affective, biological, and cognitive models to explain the emergence of the gender difference in depression . Psychol Rev 115: 291 – 313 .

Google Scholar Medline | ISI

Jakupcak, M, Tull, M, Roemer, L ( 2005 ) Masculinity, shame, and fear of emotions as predictors of men’s expressions of anger and hostility . Psychol Men Masc 6: 275 – 284 .

Google Scholar

Johnson, MP ( 2006 ) Conflict and control: Gender symmetry and asymmetry in domestic violence . Violence Against Women 12: 1003 – 1118 .

Google Scholar SAGE Journals | ISI

Kraehenmann, R, Preller, KH, Scheidegger, M. ( 2015 ) Psilocybin-induced decrease in amygdala reactivity correlates with enhanced positive mood in healthy volunteers . Biol Psychiatry 78: 572 – 581 .

Google Scholar Medline | ISI

Kraehenmann, R, Schmidt, A, Friston, K. ( 2016 ) The mixed serotonin receptor agonist psilocybin reduces threat-induced modulation of amygdala connectivity . Neuroimage Clin 11: 53 – 60 .

Google Scholar Medline

Krebs, TS, Johansen, PØ ( 2012 ) Lysergic acid diethylamide (LSD) for alcoholism: Meta-analysis of randomized controlled trials . J Psychopharmacol 26: 994 – 1002 .

Google Scholar SAGE Journals | ISI

Krueger, RF, Markon, KE, Patrick, CJ. ( 2005 ) Externalizing psychopathology in adulthood: A dimensional-spectrum conceptualization and its implications for DSM–V . J Abnorm Psychol 114: 537 – 550 .

Google Scholar Medline | ISI

Kurz, D ( 1989 ) Social science perspectives on wife abuse: Current debates and future directions . Gend Soc 3: 501 – 513 .

Google Scholar SAGE Journals

Linehan, M ( 1993 ) Cognitive–Behavioral Treatment of Borderline Personality Disorder. New York : Guilford Press .

Google Scholar

Maldonado, RC, DiLillo, D, Hoffman, L ( 2014 ) Can college students use emotion regulation strategies to alter intimate partner aggression-risk behaviors? An examination using I3 theory . Psychol Violence 5: 46 – 55 .

Google Scholar

Moore, TM, Stuart, GL ( 2005 ) A review of the literature on marijuana and interpersonal violence . Aggress Violent Behav 10: 171 – 192 .

Google Scholar ISI

Nichols, DE ( 1986 ) Differences between the mechanism of action of MDMA, MBDB, and the classic hallucinogens. Identification of a new therapeutic class: Entactogens . J Psychoactive Drugs 18: 305 – 313 .

Google Scholar Medline | ISI

Nichols, DE ( 2004 ) Hallucinogens . Pharmacol Ther 101: 131 – 181 .

Google Scholar Medline | ISI

Nolen-Hoeksema, S ( 1991 ) Responses to depression and their effects on the duration of depressive episodes . J Abnorm Psychol 100: 569 – 582 .

Google Scholar Medline | ISI

Nolen-Hoeksema, S ( 2012 ) Emotion regulation and psychopathology: The role of gender . Annu Rev Clin Psychol 8: 161 – 187 .

Google Scholar Medline | ISI

Orr, D ( 1995 ) Fundamentals of Applied Statistics and Surveys. New York : Chapman and Hall .

Google Scholar

Preller, KH, Pokorny, T, Krähenmann, R. ( 2015 ) The effect of 5-HT2A/1a agonist treatment on social cognition, empathy, and social decision-making . Eur Psychiatry 30: 22 .

Google Scholar

Ross, S, Bossis, A, Guss, J. ( 2016 ) Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: A randomized controlled trial . J Psychopharmacol 30: 1165 – 1180 .

Google Scholar SAGE Journals | ISI

Saunders, JB, Aasland, OG, Babor, TF. ( 1993 ) Development of the Alcohol Use Disorders Identification Test (AUDIT): WHO collaborative project on early detection of persons with harmful alcohol consumption-II . Addiction 88: 791 – 804 .

Google Scholar Medline | ISI

Schultes, RE, Hoffman, A, Ratsch, C ( 1992 ) Plants of the Gods: Their Sacred, Healing, and Hallucinogenic Powers. Rochester, VT : Healing Arts Press .

Google Scholar

Shrout, PE, Bolger, N ( 2002 ) Mediation in experimental and nonexperimental studies: New procedures and recommendations . Psychol Methods 7: 422 – 445 .

Google Scholar Medline | ISI

Smith, PH, Homish, GG, Collins, RL. ( 2014 ) Couples’ marijuana use is inversely related to their intimate partner violence over the first 9 years of marriage . Psychol Addict Behav 28: 734 – 742 .

Google Scholar Medline | ISI

Stith, SM, Smith, DB, Penn, CE. ( 2004 ) Intimate partner physical abuse perpetration and victimization risk factors: A meta-analytic review . Aggress Violent Behav 10: 65 – 98 .

Google Scholar ISI

Stinson, FS, Grant, BF, Dawson, DA. ( 2005 ) Comorbidity between DSM-IV alcohol and specific drug use disorders in the United States: Results from the National Epidemiologic Survey on Alcohol and Related Conditions . Drug Alcohol Depend 80: 105 – 116 .

Google Scholar Medline | ISI

Stuart, GL, O’Farrell, TJ, Temple, JR ( 2009 ) Review of the association between treatment for substance misuse and reductions in intimate partner violence . Subst Use Misuse 44: 1298 – 1317 .

Google Scholar Medline | ISI

Straus, MA, Douglas, EM ( 2004 ) A short form of the Revised Conflict Tactics Scales, and typologies for severity and mutuality . Violence Vict 19: 507 – 520 .

Google Scholar Medline

Strube, MJ ( 1985 ) PRORATE: A BASIC program for calculating minimum test length given internal consistency constraints . Behav Res Methods Instrum Comput 17: 580 .

Google Scholar

Swan, SC, Snow, DL ( 2002 ) A typology of women’s use of violence in intimate relationships . Violence Against Women 8: 286 – 319 .

Google Scholar SAGE Journals | ISI

Tomlinson, NF, Brown, M, Hoaken, PNS ( 2016 ) Recreational drug use and human aggressive behavior: A comprehensive review since 2003 . Aggress Violent Behav 27: 9 – 29 .

Google Scholar

Tupper, KW, Wood, E, Yensen, R. ( 2015 ) Psychedelic medicine: A re-emerging therapeutic paradigm . Can Med Assoc J 187: 1054 – 1059 .

Google Scholar Medline | ISI

Vollenweider, FX, Vollenweider-Scherpenhuyzen, MF, Bäbler, A. ( 1998 ) Psilocybin induces schizophrenia-like psychosis in humans via a serotonin-2 agonist action . Neuroreport 9: 3897 – 3902 .

Google Scholar Medline | ISI

Walsh, Z, Swogger, MT, O’Connor, BP. ( 2010 ) Subtypes of partner violence perpetrators among male and female psychiatric patients . J Abnorm Psychol 119: 563 – 574 .

Google Scholar Medline | ISI

Walsh, Z, Hendricks, PS, Smith, S. ( 2016 ) Hallucinogen use and intimate partner violence: Prospective evidence consistent with protective effects among men with histories of problematic substance use . J Psychopharmacol 30: 601 – 607 .

Google Scholar SAGE Journals | ISI

Walsh, Z, Gonzalez, R, Crosby, K. ( 2017 ) Medical cannabis and mental health: A systematic and guided review . Clin Psychol Rev 51: 15 – 29 .

Google Scholar Medline

Watts, A ( 1968 ) Psychedelics and religious experience . California Law Review 56(1): 74 – 85 .

Google Scholar