Give this pig a pardon!

A 180-pound, domesticated porker named Wilbur is set to be seized by the city and “disposed of” on Tuesday — despite being an emotional support animal for a family on Staten Island, his owner says.

“We need Wilbur now more than ever,” Cristy Matteo, 46, of Great Kills, told The Post on Monday night.

Her father, Thomas Matteo, 76, recently found out that he has cancer again — and the only way he’s been able to deal with the stress and anxiety of treatment, she says, is by spending time with Wilbur.

“He’s a very loving, compassionate pet,” Matteo said of the Staten Island swine. “I’m just praying the mayor will give him a pardon, or at least a stay or something like that. It would devastate me and break our hearts if we lost him.”

According to Matteo, the city has ordered her to get rid of Wilbur by midnight on Jan. 31. If she doesn’t, they told her they would “seize him and dispose of him the way they want.”

“He’s domesticated,” Matteo said of Wilbur, who is officially listed as an ESA on the National Service Animal Registry. “He doesn’t know how to be outside. He’s been brought up in a house his whole life.”

Owning pigs is illegal under New York City law, and it was reportedly the Department of Health that ordered Wilbur’s removal. The only way he can be saved, Matteo said, is if Mayor Bill de Blasio personally steps in and does something.

“I’m still praying,” she explained.

Matteo told The Post that if she could speak to the mayor herself, she would tell him of all the times Wilbur has helped her and her dad get through things emotionally, since coming into their lives five years ago.

“I would just ask him for some compassion for me and my father and to allow him to stay,” she said. “To stay where he belongs — in my home.”

Describing the situation as “heartbreaking,” Matteo recalled how she spent the past several months forming petitions and getting help from local politicians, to no avail.

“I’ve had every congressman and every senator write me letters,” she said. “In fact, I even got a letter from my dad’s oncologist, saying Wilbur had provided so much happiness for him, that he was able to take less anxiety medication for the radiation.”

One of the ways Wilbur helps out most, Matteo said, was in the way he greets her father when he returns home from treatment.

“The minute my dad walks through the door, Wilbur will go lay down in front of his chair, before he can even sit down,” she explained. “He’ll roll over and just be laying there, waiting for him to scratch his belly. That alone brings his stress levels down tremendously.”

Since being told to get rid of Wilbur, Matteo has teamed up with Sen. Tony Avella, a city mayoral candidate, to propose a new law legalizing the ownership of pigs under 200 pounds.

“Even after this, regardless of the outcome, I am going to help Avella because he’s trying to change the law,” Matteo said. “I am going to continue to fight this.”