Gov. Andrew Cuomo drew fire on Thursday for joking at the state Democratic convention that his younger brother, CNN anchor Chris Cuomo, has “certain development issues.”

“This morning I did CNN. I have a brother. He’s not a natural brother, he’s adopted. But we treat him like he’s a natural brother,” the governor said in what was intended as good-natured ribbing during his address at Hofstra University.

“It’s actually a funny story. He was found at our front door in a basket and he was 16 years old. So he has certain development issues.”

But the Republican nominee for governor, Marc Molinaro, said not only was Cuomo’s joke not funny but it was an insensitive slap at people with disabilities.

“Gov. Cuomo should stick with being angry and misleading because his joke mocking the issue of individuals with developmental disabilities is shameful,” said Molinaro, the Dutchess County executive.

“We need elected leaders who are willing to think differently instead of speaking ignorantly. If Gov. Cuomo has any decency he will apologize.”

It’s not the first time that Cuomo’s hard-edged humor led to criticism.

In March, the governor made fun of the “rhythm” of “our Jewish brothers and sisters” during a speech at a predominantly black Baptist church in Harlem.

“I want you to know as a matter of full disclosure, I am a Catholic. Catholics basically believe the same teachings that Baptists believe,” he said. “We just do it without the rhythm. But we try. We are not as without rhythm as some of our Jewish brothers and sisters.”

Cuomo referred to the off-beat swaying of Democratic consultant Hank Sheinkopf, a former campaign adviser who is Jewish and was sitting in the front row wearing a yarmulke.

“I was watching Mr. Sheinkopf here in the front row moving to the music,” Cuomo said of the consultant, who was ordained as an Orthodox rabbi in 2011. “It was ugly, I’ll tell you the truth.”

A Cuomo spokeswoman later said the governor was poking fun at himself and his friend in the audience, Sheinkopf.

The governor’s office did not have an immediate comment to Molinaro’s criticism.