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CNN’s Anderson Cooper is “genuinely sorry” for an off-color remark he made during a Friday interview with Jeffrey Lord.

Lord, a Trump supporter and frequent CNN contributor, was defending President Trump to Cooper amid reports that he called former F.B.I. chief James Comey a “nut job” when the CNN anchor interrupted him.

“If he took a dump on his desk, you would defend it,” Cooper said to Lord, who laughed in surprise. “I mean, I don’t know what he would do that you would not defend. I mean, you’re a loyal guy, I think that speaks well of you.”

Cooper later apologized on Twitter for the comment. “I regret the crude sentence i spoke earlier tonight and followed it up by apologizing on air. It was unprofessional. I am genuinely sorry.”

Last week, Cooper went viral when he let an “eye roll” at Kellyanne Conway let during an interview discussing Comey’s firing. Conway later called the remark sexist.