2. Health in the cornerback ranks: Through five games, cornerback Josh Norman has established himself as the most impactful player on the Redskins defense, credited with eight passes defended and one interception. He’ll be playing with a protective case on his sprained right wrist, which could hamper his ability to strip and catch balls. Norman relishes the challenge, however, vowing to “go out there one-handed,” if that’s what’s required. Meanwhile, the Redskins expect to get back the services of third-year cornerback Bashaud Breeland, sidelined the past two games by a severely sprained ankle. Rookie Kendall Fuller has earned the starting spot in the slot. The trio should suffice against a passing game that isn’t the Eagles’ strength.

3. Change-up in the running game? Matt Jones has run hot and cold in his second Redskins season, following a 117-yard, one-touchdown performance against Cleveland with a spotty showing at Baltimore, where he fumbled once and was stopped on fourth and one. The Eagles allow opponents just 73.3 rushing yards per game, third-stingiest in the NFL. Expect Gruden to vary the look of his rushing attack by adding carries for rookie Robert Kelley, who gained impressive ground against Baltimore last week when Jones was stymied. Kelley has also shown welcome savvy in pass protection.

4. Weathering Philadelphia’s defense: Quarterback Kirk Cousins and the right side of the offensive line face a stiff challenge in the Eagles’ Pro Bowl defensive lineman Fletcher Cox, who has four sacks and 11 quarterback hurries in four games. Cox twice sacked Ben Roethlisberger, the Steelers quarterback whom the Redskins barely touched, in the Eagles’ Week 3 upset, and also forced two fumbles. Cox is one among many imposing figures on a defense that ranks second in points allowed (12.6 per game) and yards allowed (266.8 ypg). The Eagles defense ranks fourth in third-down conversion rate (32 percent), while the Redskins rank last (48 percent). The Eagles also average 3.5 sacks per game, compared to the Redskins’ 2.2.

5. Rattling rookie quarterback Carson Wentz: Along with Dak Prescott of Dallas, Philadelphia quarterback Carson Wentz has far surpassed expectations in the season’s early going. The 6-foot-5, 237-pound Wentz, acquired with the second pick in the NFL draft, showed enough in training camp to convince the front office to cut short his incubation period as starter-in-waiting, trade the brooding Sam Bradford on the eve of the season and put the offense in Wentz’s hands. He has shown poise and command, throwing his first interception on a last-second desperation heave in last week’s loss to Detroit. In the view of Redskins defensive coordinator Joe Barry, Wentz’s ability to improvise when plays break down and minimize turnovers stand out.