Donna Shalala, the former president of the University of Miami who was brought in to lead the Clinton Foundation this year, had a stroke shortly after the closing ceremonies of the organization’s major fall event early Tuesday evening, officials said.

Ms. Shalala, 74, fell ill after departing the closing events around the Clinton Global Initiative, which was held at the Sheraton New York hotel on Seventh Avenue in Manhattan, according to a statement from foundation officials.

An email from former President Bill Clinton and his daughter, Chelsea, who is the vice chairwoman of the foundation and a major force in running the organization, was sent to the staff late in evening.

“As some of you may have heard, Donna suffered a stroke this evening after CGI,” the email read. “Fortunately, she was with colleagues at the time and taken to the hospital for treatment. Initial reports are very encouraging.” They added, “We will continue to share updates as we know more. Please join Hillary, Chelsea and me in keeping Donna in your thoughts and prayers.”