Modafinil Dosage of 200 mg

This is the standard dose taken by most smart drug users who are seriously using Modafinil to become more energetic and focused for the majority of the working day.

As mentioned before, it is also the most “well-researched” dosage of Modafinil and it is officially recommended in Modafinil’s product monograph [12]:

“The recommended starting daily dose is 200 mg. The total daily dose may be taken as a single dose in the morning or as two doses, one in the morning and one at noon, according to physician assessment of the patient and the patient’s response.”

At 200 mg of Modafinil, most users feel all the desired cognitive effects with little to no side effects.

We recommend most Modafinil users stick with this dose at 1-3 days per week. There’s very little evidence to suggest more than 200 mg of Modafinil adds additional benefits, or that splitting your Modafinil dosage into two 100mg doses makes any real difference.

Modafinil Dosage of 300 mg

Unless you absolutely need an additional 1-2 hours of focus, or plan on staying up for more than 24 hours, 300 mg of Modafinil is not recommended.

Even if taken early in the morning, our test subjects reported extreme difficulty with falling asleep before 3-4am, and woke up feeling “slightly hungover” the next morning.

This Modafinil dosage has not been extensively studied in the literature, but some of the studies make several suggestions that are in line with our own observations.

In one study comparing different levels of Modafinil dosing to 100 mg of caffeine, using 300 mg of Modafinil to power through sleep deprivation lowered performance the very next day [13]:

“Enhanced performance with modafinil during overnight work varied with dose (200 mg>100 mg; 300, 400 mg>200, 100 mg, caffeine). However, in the study of next-day performance, the enhancement was attenuated at the highest dose (300 mg) by the greater disturbance of prior sleep.”

However, in another study dosing Modafinil in French military soldiers deprived of sleep for 64 hours, 300 mg of Modafinil was the only dose that allowed them to maintain the same level of cognitive performance relative to baseline levels [14].

If you decide to use this dosage of Modafinil, we highly recommend splitting your daily dose into two smaller doses: 150 mg in the early morning, and 150 mg right after eating lunch.

Modafinil Dosage of 400 mg

For the purpose of cognitive enhancement, this Modafinil dosage is not advisable for the majority of smart drug users.

Even physicians are recommended not to go any higher than 400 mg of Modafinil a day for patients suffering from shift work sleep disorder, narcolepsy, or sleep apnea [15].

We have only found a few instances where 400 mg of Modafinil may be required for enhancing cognition:

An unusual metabolism whereby Modafinil is eliminated at a faster rate

Individuals who have developed a heavy tolerance to Modafinil (to which we would advise an extended break from Modafinil to ‘reset’ the body)

Smart drug users who are larger in size (>200 lbs, and >6 feet tall)

Most of our users started experiencing a higher frequency and severity of side effects at this high dose of Modafinil — brain fog, chronic fatigue, difficulty concentrating, lower energy levels, and so on.

Moreover, the positive aspects of Modafinil tend to quickly wear out, possibly leading to overconfidence in your own mental capabilities [16]:

“A single dose of modafinil seems to have a cognitive enhancing effect in cases of moderate sleep deprivation. In repeated doses it does not seem to boost cognitive performance over a longer period of sleep deprivation, but only maintains wakefulness.”

In summation, 400 mg of Modafinil should be avoided unless you have a clinical need for it.