For abortion, the first pill is taken with water on a dose of 200 mg orally once. Following 24 hours, the second pill of misoprostol can be used by putting the tablets in each cheek pouch keeping it there for around half an hour. For any additional remains swallow it with water. It can also be done by ingesting vaginally. Pregnancy termination is not completed if one vomits within using the second pill, or urinates if used vaginally.

If there is any doubt about the pregnancy, it is required to visit the doctor and monitor the nature of the bleeding.