NEW YORK—World leaders will tackle the mass flight of minority Muslims from Burma when they gather at the United Nations on Monday.

The Rohingya crisis will be one of several global challenges facing the General Assembly, along with an escalating nuclear threat from North Korea, the spread of terrorism and climate change.

The spotlight will be on U.S. President Donald Trump and France’s new leader, Emmanuel Macron, who will both be making their first appearance at the assembly. They will be joined by more than 100 heads of state and government, including Zimbabwe’s President Robert Mugabe, one of Africa’s longest-serving leaders who is said to be bringing a 70-member entourage.

In its first statement on Burma in nine years, the Security Council condemned the violence that has driven nearly 400,000 to flee Bangladesh in the past three weeks and called for immediate steps to end it. British Foreign Secretary Boris Johnson is hosting a closed meeting on the crisis Monday, and the Organization of Islamic Cooperation’s contact group on the Rohingyas is scheduled to meet Tuesday.

On Thursday, Bangladesh’s Prime Minister Sheikh Hasina is scheduled to attend the General Assembly in New York, where she is expected to ask for help from the international community to tackle the situation.

“We want peace; we want good relations with our neighbouring countries,” she said. “But we can’t tolerate and accept any injustice.”