Climbers hoping to scale one of Australia's most significant landmarks have less than an hour before the Uluru climb is permanently closed.

Key points: Hundreds of visitors have scrambled up the sandstone of Uluru

Hundreds of visitors have scrambled up the sandstone of Uluru Tomorrow marks 34 years since land title was handed back to the Anangu people

Tomorrow marks 34 years since land title was handed back to the Anangu people The permanent closure of the climb was announced two years ago

Rangers are preparing to shut the Uluru climb for the final time, as the last groups of tourists ascend the rock.

Hundreds of people have made the trek up the rock today, with many saying they had wanted to do the climb while they still could.

The climb is scheduled to be closed permanently from 4:00pm (ACST).

The climb was closed earlier this morning because of strong winds but rangers at Uluru decided to reopen it mid-morning and almost 100 people immediately began climbing.

The last day of the Uluru climb reopens after delays due to strong wind. ( ABC News: Samantha Jonscher )

Weather almost thwarts travelling visitors

Katrina and Paul Ballinger from Ballarat were among those lining up to climb the rock this morning and said they were relieved when they were allowed through the gate.

"Amazing, I'm glad that we travelled all this way to actually get on the rock," Ms Ballinger said.

"It will be great, [we] can't wait."

Katrina and Paul Ballinger from Ballarat were among those lining up to climb the rock. ( ABC News: Samantha Jonscher )

Earlier, Noel and Kelly Derks from Melbourne, who have already climbed the rock four times, were concerned the weather would prevent their children from experiencing the climb.

"Safety is first, there's no problem with that," Mr Derks said.

"It would have been great to get one more in."

The Derks said, even with the climb closed, they would be back to visit Uluru.

"Definitely, we'll be back in another 20 years, hopefully with grandkids. It's still a beautiful place," Mr Derks said.

Noel and Kelly Derks have returned to climb Uluru for the fifth time. ( ABC News: Samantha Jonscher )

Dean Beveridge and his wife Chris, who are also from Melbourne, were waiting at the base of the climb this morning to see if it would reopen before the permanent closure.

"My wife and I climbed it years ago and we just wanted the kids to have the opportunity to do that," Mr Beveridge said.

Mr Beveridge said he believed it was still possible to climb Uluru while showing respect to the traditional owners who urge people not to climb.

"Whilst I respect that, I wish there was an opportunity for them to maybe understand that there are different ways we show respect to people's religious sites."

Dean and Chris Beveridge made the trip to Uluru to do the climb with their children but were worried it would not reopen due to weather conditions. ( ABC News: Samantha Jonscher )

Parks monitoring weather conditions

Parks Australia said it would continue to make assessments on the safety of the climb before the official closure at 4:00pm ACST this afternoon.

Parks Australia operations and visitor services manager Steve Baldwin said people queueing up this morning shouldn't feel aggrieved a possible early closure due to poor weather.

"Anangu and the [Uluru] board provided two year's notice because they were mindful that people wanted to climb," he said.

"So they shouldn't be surprised, it's been a long time coming."

The safety of the climb will be last assessed at 2:00pm ACT. ( ABC News: Samantha Jonscher )

Rush to beat climb ban saddens traditional owners

As huge crowds line up at the base of Uluru, the influx has frustrated traditional owners, who have long campaigned for the climb's closure.

The permanent closure of the climb was announced two years ago, but in recent months Uluru-Kata Tjuta National Park has seen thousands of tourists flock to climb the rock before they no longer can.

Custodian Leroy Lester says he does not blame people for wanting to climb, "it's in their genes". ( ABC: Samantha Jonscher )

Uluru is a sacred site and of great spiritual significance to First Australians, and Anangu traditional owners say climbing it is not only disrespectful but also dangerous.

In Uluru's history, at least 37 people have died while making the ascent.

Uluru custodian Leroy Lester said there were several reasons why Anangu wanted the climb closed.

"Mainly because it's a sacred site and mainly because for safety reasons, pollution on top, no toilets up there and E. coli killing all the organisms, all the frogs and everything," he said.

"And it's very, very dangerous."

Mr Lester said the large number of people travelling to climb the rock in the face of objections by traditional owners represented a clash of cultures in Australia.

"A different culture, conquer and divide, you can't blame them. It's in their genes, that Anglo-Saxon way," he said.

Mr Lester said he wasn't sure people would respect the closure of the climb.

"Some will, some won't. 50/50 depending on how well people are educated on the matter, on Aboriginal culture, how they accept Aboriginal culture and respect it," he said.

"But we just have to see."

'Equivalent to rushing to climb War Memorial'

Indigenous Affairs Minister Ken Wyatt says he has been disappointed by the large numbers of people rushing to climb Uluru before it closes.

"I understand there are people that want to put it on their bucket list," he said.

Mr Wyatt said the Uluru climb continued to be an affront to traditional owners. ( ABC News: Tim Leslie )

"It would be equivalent to having a rush of people wanting to climb over the Australian War Memorial.

"Our sacred objects, community by community, are absolutely important in the story and the history of that nation of people."

Mr Wyatt said people who have climbed Uluru in the past should reflect on how they've disrespected traditional owners.

"I wouldn't want to curse anybody nor leave them with negative elements of life," he said.

"But reflect back what you've done and reflect back on the fact you've disrespected a community of traditional owners who have always wanted the right to have a say about what is sacred to them."

'This is about coming together'

Northern Territory senator Malarndirri McCarthy has urged Australians to respect the wishes of traditional owners ahead of the climbing ban.

"The Anangu traditional owners have repeatedly expressed a desire for people to show respect to the rock's cultural value by not climbing it," she said.

Senator Malarndirri McCarthy stressed unity before the Uluru climb closure. ( ABC News: Mitch Woolnough )

Senator McCarthy told Channel Nine it was important to recognise times and attitudes had changed.

"This is more about the coming together," she said.

"I think in Australia we are acknowledging the importance of First Nations people in our place, in our history in this country, and around the world."