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Pending shareholder and regulatory approval, the deal is scheduled to close by the end of October.

But the investment, which the companies said would be “the largest to date in the cannabis space,” will apparently draw scrutiny from the Canadian government as well.

“We can confirm that U.S.-based Constellation Brands Inc.’s proposed investment in Canopy Growth Corporation is subject to review under the Investment Canada Act,” said Hans Parmar, a spokesperson for Innovation, Science and Economic Development Canada, in an email on Friday. “The proposed acquisition, like all foreign investment transactions, will be reviewed on its merits based on the overall economic benefit for Canada.”

That review is also likely to be a first for Canada, the spokesperson added.

“The proposed transaction would very likely be the first cannabis-related investment reviewed under the Act given the only recent passing of legislation to legalize cannabis,” Parmar said.

A presentation on the deal by Constellation had suggested the transaction may require approval under the Investment Canada Act, legislation that says it is intended to “provide for the review of significant investments in Canada by non-Canadians.” An order issued under the same act scuttled a proposed takeover of Canadian construction firm Aecon Group Inc. by a Chinese state-owned company earlier this year, albeit in the name of national security.