Very Low Calorie Diet In Type 2 Diabetes (Newcastle University) Taylor R MD (2014) Type 2 diabetes mellitus is generally regarded as an irreversible chronic condition. As a very low calorie diet can bring about…

http://www.ncl.ac.uk/magres/research/diabetes/documents/VerylowcaloriedietS.Stevenetal.pdf

Pathogenesis Of Type 2 Diabetes: Tracing the Reverse Route… (PubMed) Taylor R MD (2008) The metabolic abnormalities of type 2 diabetes can be reversed reproducibly by bariatric surgery. By quantifying the major…

https://www.ncbi.nlm.nih.gov/pubmed/18726585

Reversal Of Type 2 Diabetes: Normalisation Of Beta Cell Function… (PubMed) Taylor R MD (2011) Type 2 diabetes is regarded as inevitably progressive, with irreversible beta cell failure. The ypothesis was tested that both beta cell…

https://www.ncbi.nlm.nih.gov/pubmed/21656330

Population Response To Information On Reversibility… (Newcastle University) Taylor R MD (2013) Following publication of the Couterpoint Study on the reversibility of Type 2 diabetes using a very low energy diet, the extent of public…

http://www.ncl.ac.uk/magres/research/diabetes/documents/CounterpointReflections.pdf

Reversing The Twin Cycles Of Type 2 Diabetes… (Newcastle University) Taylor R MD (2012) It has become widely accepted that Type 2 diabetes is inevitably life-long, with irreversible and progressive beta cell damage…

http://www.ncl.ac.uk/magres/research/diabetes/documents/BantingDiabeticMed.pdf

Insulin Independent Glucose Transport Regulates Insulin Sensitivit… (PubMed) Ebeling P (1998) The glucose transport proteins (GLUT1 and GLUT4) facilitate glucose transport into insulin-sensitive cells. GLUT1 is insulin independent…

https://www.ncbi.nlm.nih.gov/pubmed/9801136

Functional Properties And Genomics Of Glucose Transporter (PubMed) Zhao FQ (2007) Glucose is the major energy source for mammalian cells as well as an important substrate for protein and lipid synthesis. Mammalian cells…

https://www.ncbi.nlm.nih.gov/pubmed/18660845

A Comparison Of Basel And Insulin Stimulated Glucose Transport… (PubMed) Ludvigsen C (1980) Specific D-glucose transport in plasm membranes prepared from control and insulin treated rat adipocytes was measure using a recently…

https://www.ncbi.nlm.nih.gov/pubmed/6991329

Estimation And Kinetic Analysis Of Insulin Independent Glucose… (PubMed) Gottesman I (1983) Using the glucose clamp technique, glucose uptake was determined isotopically in normal human volunteers at plasma glucose…

https://www.ncbi.nlm.nih.gov/pubmed/6344653

An Analysis Of How To Measure Glucose During Glucose Clamps… (PubMed) Hompesch M (2008) This article provides a perspective on the challenges of appropriate glucose measurement in the context of glucose clamp experiments.

https://www.ncbi.nlm.nih.gov/pubmed/19885275 Showing 1-10 of 74 Show All

The Contribution Of Insulin Dependent And Insulin Independent… (PubMed) Kahn SE (1994) Glucose disposal occurs by both insulin independent and insulin dependent mechanisms, the latter being determined by the interaction of…

https://www.ncbi.nlm.nih.gov/pubmed/8138065

Fasting Hyperglycemia In Non-Insulin-Dependent Diabetes Mellitu… (PubMed) DeFronzo RA (1989) The factors responsible for fasting hyperglycemia were investigated in 77 normal weight non-insulin-dependent diabetic and 72 Age…

https://www.ncbi.nlm.nih.gov/pubmed/2657323

Hyperglycemia-Induced Stimulation Of Glucose Transport In Skele… (PubMed) Huang HM (2012) A physiologically based model proposed by our group has been developed to assess glucose transport and phosphorylation in skeletal…

https://www.ncbi.nlm.nih.gov/pubmed/22986442

Cardiac And Adipose Tissue Abnormalities But Not Diabetes In… (PubMed) Katz (1985) The insulin-sensitive glucose transporter, GLUT4, is the most abundant facilitative glucose transport in muscle and adipose tissue, the…

https://www.ncbi.nlm.nih.gov/pubmed/7675081

Normal Muscle Glucose Uptake In Mice Deficient In Muscle GLUT4 (PubMed) Fam BC (2012) Skeletal muscle insulin resistance is a major characteristic underpinning type 2 diabetes. Impairments in the insulin responsiveness…

https://www.ncbi.nlm.nih.gov/pubmed/22736482

Insulin, Growth Hormone And Sport (PubMed) Sonksen PH (2001) This review examines some interesting ‘new’ histories of insulin and reviews our current understanding of its physiological actions …

https://www.ncbi.nlm.nih.gov/pubmed/11431133

Biological Active Ingredients Of Traditional Chinese Herb Astragalu… (PubMed) Zhang K (2015) Diabetes mellitus is a serious chronic metabolic disease which disease afflicting at present no afflicts approximately 4% of world population…

https://www.ncbi.nlm.nih.gov/pubmed/25723453

Effects Of Astragalus Membranaceus Extract On Diabetic Nephrapa… (PubMed) Kim J (2014) Diabetic nephropathy, a microvascular complication of diabetes, is a progressive kidney disease caused by angiopathy of the capillaries in the kidney…

https://www.ncbi.nlm.nih.gov/pubmed/25298884

Characterization And Hypoglycemic Effect Of A Polysaccharide … (PubMed) Zhu J (2013) Diabetes mellitus is a group of complicated metabolic disorders characterized by high blood glucose level and inappropriate insulin secreting…

https://www.ncbi.nlm.nih.gov/pubmed/23987311

The Protective Effects Of Lycium Barbarum And Chrysanthemum… (PubMed) Hu CK (2012) the effects of Lycium barbarum and Chrysanthemum morifolum extracts on diabetic retinopathy were evaluated. The diabetes model was…

https://www.ncbi.nlm.nih.gov/pubmed/22487267

Hypoglycemic And Hypolipidemic Effects And Antioxidand Activity… (PubMed) Luo Q (2004) The hypoglycemic and hypolipidemic effects of Lycium babarum fruit water decoction, crude polysaccharide extracts, and purified polysaccharide…

https://www.ncbi.nlm.nih.gov/pubmed/15519360

The Effects Of Enriched Chicory Inulin On Liver Enzymes, Calcium… (PubMed) Farhangi MA (2016) Type 2 diabeteic mellitus as one of the main causes of morbidity and mortality is associated with immune system distrubances…

https://www.ncbi.nlm.nih.gov/pubmed/26872721

Effects Of The Extracts From Roasted Chicory (Cichorium Intybus L)… (PubMed) Nishimur M (2015) The extract from roasted chicory root, which contains inulin type fructans, has favorable effects including antihyperglycemic and…

https://www.ncbi.nlm.nih.gov/pubmed/26151029

Dicaffeoyloquinic Acid Enriched Fraction Of Cichorium Glandulosm… (PubMed) Tong J (2015) Chicory has a major geographical presence in Europe and Asia. Gichorium glandulosum Boiss. Et Huet, a genus of Cichorium, is used for…

https://www.ncbi.nlm.nih.gov/pubmed/26586022

Amerlioration By Chicory Seed Extract Of Diabetes And Oleic… (PubMed) Ziamajidi N (2013) We evaluated the effects of chicory seed extract on hepatic steatosis caused by elary and late stage diabetes in rats (in vivo) and induced…

https://www.ncbi.nlm.nih.gov/pubmed/23603006

Effects Of Chicory Seed Extract On Glucose Tolerance Test And… (PubMed) Ghamarian A (2012) The goal was to evaluate and compare the effects of aqueous extract of the seeds of chicory, Cichorium Intybus L, on glucose…

https://www.ncbi.nlm.nih.gov/pubmed/23352214

Effects Of Chinese Herbal Medicine Shenxiong Yujing Granule On… (PubMed) Han H (2012) To establish a rat model of diabetes associated cerebral ischemia due to qi and yin deficiency and blood stasis, and to investigate the effects…

https://www.ncbi.nlm.nih.gov/pubmed/23073198

Antihyperglycemic Effects Of Total Flavonoids From Polygonatum… (PubMed) Shu XS (2009) Total flavonoids of Polygonatum adoratum were tested for anti-diabetic activity in streptozotocin induced diabetic mice and alloxan induced…

https://www.ncbi.nlm.nih.gov/pubmed/19454312

Hypoglycemic Effects Of Aqueous Extract Of Rhizoma Polygonati… (PubMed) Chen H (2001) Water soluble extract of Rhizoma Polygonati Odorati was studied for its hypoglycemic effect in diabetic mice and rats. Results showed that RPO…

https://www.ncbi.nlm.nih.gov/pubmed/11274822

Hypoglycemic Activity Of Polygonati Rhizoma In Normal And… (PubMed) Kato A (2008) The hypoglycemic effect of different does of Polygonati Rhizoma was investigated in both normal and streptozotocin induced diabetic mice…

https://www.ncbi.nlm.nih.gov/pubmed/8312868

4-Hydroxyisoleucine: A Potential New Treatment For Type 2 Diabe… (PubMed) Zafar MI (2016) 4-Hydroxyisoleucine is a compound found in Trigonella foenum graecum (fenegreek) seeds, which have been used as part of traditional…

https://www.ncbi.nlm.nih.gov/pubmed/27151154

Prevention Effects And Possible Molecular Mechanism Of Mulberry… (PubMed) Liu Y (2016) For centuries, mulberry leaf has been used in traditional Chinese medicine for the treatment of diabetes. This study aims to test the prevention…

https://www.ncbi.nlm.nih.gov/pubmed/27054886

Pharmacodynamic Interaction Of Fenugreek, Insulin And Glimepiri… (PubMed) Haritha C (2015) this study was undertaken to assess the pharmacodynamics interaction of fenugreek, insulin and glimepiride on sero-biochemical…

https://www.ncbi.nlm.nih.gov/pubmed/27047152

Effectiveness Of Phytotherpy In Supportive Treatment Of Type 2… (PubMed) Koupy D (2015) Fenugreek seeds are known for their characteristic smell of soup seasoning and as an ingredient of Indian curry. Traditionally the seeds are used…

https://www.ncbi.nlm.nih.gov/pubmed/26400229

Effect Of Fenugreek Seeds On Serum Metabolic Factors And… (PubMed) Rafraf M (2014) This triple blind randomized controlled clinical trial was conducted on 88 type 2 diabetic patients. Subjects in the fenugreek seed…

https://www.ncbi.nlm.nih.gov/pubmed/26098483

Potential Ocular Protection And Dynamic Observation Of Polygona… (PubMed) Wang Y (2016) Ocular complications associated with diabetes mellitus are progressive and becoming one of the most important causes of morbidity…

https://www.ncbi.nlm.nih.gov/pubmed/27510582

Antidiabetic Effect Of Total Saponins From Polygonatum Kingianu… (PubMed) Lu JM (2016) Polygonatum kingianum has been used in the prevention and treatment of diabetes, hyperlipidemia and related metabolic syndrome in Asian…

https://www.ncbi.nlm.nih.gov/pubmed/26743227

Effects Of Polygonatum Sibiricum Rhizome Ethanol Extract In High… (PubMed) Ko JH (2015) the rhizome of Polygonatum sibiricum Redoute has long been used to treat diabetes associated complications. However, the pharmacological…

https://www.ncbi.nlm.nih.gov/pubmed/25327577

Hypoclycemic Action Of the Rhizomes Of Polygonatum Officinale… (PubMed) Kato A (1994) the hypoglycemic effect of the rhizomes of Polygonatum officinale was investigated in both normal and streptozotocin induced diabetic mice…

https://www.ncbi.nlm.nih.gov/pubmed/8073082

Effect Of Mulberry Leaf On Insulin Resistance Via IRS-1/PI3k/Glut-4… (PubMed) Cai S (2016) Folium Mori, the leaf of Morus alba, has been used in traditional Chinese medicine for treating diabetes. However, it is unclear which…

https://www.ncbi.nlm.nih.gov/pubmed/27158744

The Effects Of Supplementary Mulberry Leaf Extracts On The Trace… (PubMed) Krol E (2016) Mulberry leaves have been used in folk medicine to mitigate the symptoms of diabetes. The mulberry plant contains phenolic compounds that…

https://www.ncbi.nlm.nih.gov/pubmed/27071614

Attenuation Of Endoplasmic Reticulum Stress Mediated Liver… (PubMed) Afrin R (2016) Endoplasmic reticulum stress plays a crucial role in the development of insulin resistance and diabetes mellitus. Although…

https://www.ncbi.nlm.nih.gov/pubmed/26916916

Mulberry Extract to Modulate Blood Glucose Responses In… (PubMed) Lown M (2015) Worldwide sugar consumption has tripled during the last fifty years. High sugar intake is associated with weight gain and increased…

https://www.ncbi.nlm.nih.gov/pubmed/26511964

Morus Nigra Leaf Extract Improves Glycemic Response And Redox… (PubMed) Araujo CM (2015) Diabetes mellitus is a chronic metabolic disorder characterized by hyperglycemia and alterations in the carbohydrate, lipid, and protein…

https://www.ncbi.nlm.nih.gov/pubmed/26294257

A Novel Formula From Mulberry Leaf Ameliorates Diabetic Nephro… (PubMed) Zhang Q (2015) Based on the hypoglycemia and hyperlipidemia of mulberry leaf and its extracts, we investigated the effects of a novel formula, Sang Tong Jian…

https://www.ncbi.nlm.nih.gov/pubmed/26242486

Mulberry Leaf Extract Improves Postprandial Glucose Response In… (PubMed) Kim JY (2015) This study was a randomized, double blind placebo controlled trial to assess the efficacy of 4 weeks of mulberry leaf extract supplementation for…

https://www.ncbi.nlm.nih.gov/pubmed/25343729

A Polysaccharide Extract Of Mulberry Leaf Ameliorates Hepatic… (PubMed) Ren C (2015) Mulberry leaf is a traditional medicine used to treat diabetes in the clinic. The aim of this study was to determine the mechanisms by which…

https://www.ncbi.nlm.nih.gov/pubmed/25316427

Dioscorea Extract Modulates Markers Of Peripheral Neuropathy In… (PubMed) Moon E (2014) The purpose of this study was to investigate the therapeutic effects of DA-9801, an optimized extract of Dioscorea species, on diabetic…

https://www.ncbi.nlm.nih.gov/pubmed/25414776

Potent Effects Of The Total Saponins From Dioscorea Nipponica… (PubMed) Yu H (2015) The aim of the present paper was to investigate the effects and possible mechanisms of the total saponins from Dioscorea nipponica Makino…

https://www.ncbi.nlm.nih.gov/pubmed/25322985

Diosgenin From Dioscorea Bulbifera: Novel Hit For Treatment Of… (PubMed) Ghosh S (2014) Diabetes mellitus is a multifactorial metabolic disease characterized by post prandial hyperglycemia. Amylase and glucosidase…

https://www.ncbi.nlm.nih.gov/pubmed/25216353

Anit-Diabetic Effects Of The Ethanol Extract Of A Functional… (PubMed) Cheng Q (2015) Phizoma dioscorea, Lycium barbarum, Prunella vulgaris and hawthorn are well known in both traditional food and folk medicine. Each…

https://www.ncbi.nlm.nih.gov/pubmed/24817112

Beta Cell Regenerating Potential Of Azadirachta Indica (Neem) Extr… (PubMed) McCalla G (2015) This study evaluated the ability of 0.8% neem leave extract to treat diabetes mellitus by assessing its effects on blood glucose, insulin levels…

https://www.ncbi.nlm.nih.gov/pubmed/26716795

Screening And Design Of Anti-Diabetic Compounds Sourced From… (PubMed) Jalil A (2013) Diabetes Mellitus is affecting people of all age groups worldwide. Many synthetic medicines available for type 2 diabetes mellitus in the market…

https://www.ncbi.nlm.nih.gov/pubmed/24497731

Meliacinolin: A Potent Glucosidase And Amylase Inhibitor Isolated… (PubMed) Perez-Gutierrez RM (2012) In India, Azadirachta indica is typically known as ‘neem tree’ and its leaves has long been use din the ayurvedic medical tradition…

https://www.ncbi.nlm.nih.gov/pubmed/22975503

Therapeutic Potential Of Chinese Herbal Medicines In Alcoholic Liver… (PMC) Kuan-Hung Lu (2012) Alcoholic liver disease is a complex chronic disease and is associated with a spectrum of liver injury ranging from steatosis and…

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3942913/

Protective Effect Of Platycodin D On Liver Injury In Alloxan Induce… (PubMed) Chen T (2015) Platycodin D is a major pharmacological constituent of Platycodi Radix with immunomodulatory activity. The present study was designed to…

https://www.ncbi.nlm.nih.gov/pubmed/25887267

Platyconic Acid, A Saponin From Platycodi Radix, Improves Glucos… (PubMed) Kwon DY (2012) Previous research demonstrated that the crude saponins of Platycodi radix improved glucose metabolism by enhancing insulin sensitivity…

https://www.ncbi.nlm.nih.gov/pubmed/21847688

Long Term Consumption Of Saponins Derived from Platycodi Radi… (PubMed) Kwon DY (2009) Crude saponins derived from Chinese Platycodi radix have been reported to prevent increases in body weight and liver TAG in mice fed a high…

https://www.ncbi.nlm.nih.gov/pubmed/18577298

Clinical Efficacy Of Aconitum Containing Traditional Chinese Medic… (PubMed) Feng L (2014) Diabetic peripheral neuropathy is a common chronic complication of diabetes. Routine clinical management uses analgesics to relieve pain in…

https://www.ncbi.nlm.nih.gov/pubmed/24467538

Licochalcone E Has An Anitdiabetic Effect… (PubMed) Park HG (2012) Licochalcone E is a retrochalcone isolated from the root of Glycyrrhiza inflate. Retrochalcone compounds evidence a variety of pharmacol…

https://www.ncbi.nlm.nih.gov/pubmed/21840191

In Vivo Anti-Diabetic Activity Of Derivatives Of Isoliquiritigenin… (PubMed) Gaur R (2014) Isoliquiritigenin, a chalcone and liquiritigenin, a flavonoid found in licorice roots and several other plants. ISL displays antioxidant, anti-inflammato…

https://www.ncbi.nlm.nih.gov/pubmed/24262065

Antidiabetic Effect Of Schisandrae Chinensis Fructus Involves Inhibi… (PubMed) Qu Y (2014) Preclinical Research Schisandrae Chinensis Fructus, the fruit of schisandra chinensis is traditionally used as a tonic and antidiabetic agent in…

https://www.ncbi.nlm.nih.gov/pubmed/25407144

Protective Effect Of Schisandrae Chinensis Oil On Pancreatic B-Cell… (PubMed) An L (2015) Islet cell dysfunction in Type 2 diabetes is primarily attributed to increased apoptosis of pancreatic B-Cells. The aim of the present study was…

https://www.ncbi.nlm.nih.gov/pubmed/25151401

Schizandrin Prevents Damage Of Murine Mesangial Cells Via Block… (PubMed) Jeong SI (2012) High glucose is the underlying factor contributing to long term complications of diabetes mellitus. Reactive oxygen species have been…

https://www.ncbi.nlm.nih.gov/pubmed/22138248

The Lignin-Rich Fractions Of Fructus Schisandrae Improve Insulin… (PubMed) Kwon DY (2011) Fructus Schisanddrae, the fruit of Schisandra chinensis, has been traditionally used as a hypoglycemic agent in Asia and its extracts have been…

https://www.ncbi.nlm.nih.gov/pubmed/21440615

Huang-Lian-Jie-Du-Tang Supplemented with Schisandra chinensis… (PubMed) Park S (2009) We investigated to determine what effects, if any, the respective water extracts of Radix scutellariae, Fructus schisandrae chinensis (FSC)…

https://www.ncbi.nlm.nih.gov/pubmed/19897925

Anti-Inflammatory And Anti-Superbacterial Properties Of Sulforap… (PMC) Woo Jin Choi (2014) Shepherd’s purse, Capsella bursa-pastoris Medik, has been considered a health food for centuries in Asia and is known to contain the…

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3951821/

Herbal Medicines And Nonalcoholic Fatty Liver Disease… (PMC) Hong Yao (2016) Nonalcoholic fatty liver disease, which is characterized by excessive fat accumulation in the liver of patients who consume little or no…

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974587/

Treatment Of Rats With Jiangzhi Capsule Improves Liquid Fructose… (PMC) Yuanyang Zhao (2015) Jiangzhi Capsule is an Australian listed patented traditional Chinese medicine and has been used for management of lipid…

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4467629/

Crude Extracts From Lycium Barbarum Suppress SREBP-1c Expressi… (PMC) Wang Li (2014) Lycium barbarum polysaccharide is well known in traditional Chinese herbal medicine that, has beneficial effects. Previous study reported…

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071778/

Recent Advances In The Herbal Treatment Of Non-Alcoholic Fatty… (PMC) Jia Xiao (2013) Non-alcoholic fatty liver disease is one of the leading causes of chronic liver injury across the world. It is strongly related to other pathological…

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3924972/

A Recipe Composed Of Chinese Herbal Active Components regulates… (PMC) Sheng-xi Meng (2016) This study is to investigate the therapeutic effects of the recipe composed of Atractylodes macrocephala polysaccharide, chlorogenic…

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4812184/

Chinese Medicine Formula Lingguizhugan Decoction Improves Beta… (PMC) Tao Liu (2013) Lingguizhugan decoction, a classic traditional Chinese medicine formula, has been used to treat obesity and hyperlipidemia in recent years…

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3664975/