Deutsche Bank said the job cuts would reduce the total number of its employees to about 90,000. It added that it would also seek to reduce its leverage exposure in its corporate and investment bank by 100 billion euros, or $117 billion, a cut of about 10 percent.

The announcement came just hours before the bank’s annual general meeting, during which its chairman, Paul Achleitner, is expected to come under pressure.

Mr. Achleitner, who has led Deutsche Bank’s supervisory board since 2012, has been the target of increasing criticism for the lender’s missteps. The agenda at the meeting on Thursday includes a motion to oust him, although he is expected to keep his job, because his removal would throw the bank into even greater turmoil.

The selection of Mr. Sewing had been intended to draw a line over Deutsche Bank’s various struggles — the lender had a hand in almost all of the major crises and scandals tied to the 2008 global financial crisis. It has paid billions of dollars in penalties and settlements over the fraudulent sale of mortgage-backed securities, as well as over its role in the manipulation of benchmarks used to determine the interest rates on numerous financial products.