A street artist has sent a powerful message to the Queensland premier, expressing his "disgust" over the Adani Carmichael mine deal being negotiating by the government.

Scott Marsh said he wasn't afraid of the possible repercussions of his piece, having had dealings with police due to his background in illegal graffiti when he was younger.

Queensland Premier Annastacia Palaszczuk depicted holding a gun to Nemo's head in an anti-Adani street mural in New Farm. Credit:Lisa Maree Williams

Mr Marsh had travelled up to Brisbane for a commissioned piece and started the mural on Friday afternoon before finishing about 10pm.

It was the second painting the Sydney-based artist had created relating to the Adani deal, the other having been completed in April.