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The Colts thought wide receiver Reggie Wayne tore the ACL in his right knee on Sunday night.

Now they know he did. Adam Schefter of ESPN reports that the MRI performed on Wayne’s knee on Monday confirmed the initial diagnosis and that means the Colts will now have to play the rest of the season without a player they haven’t played a single game without since the 2001 season.

The Colts don’t play again until November 3, giving them ample time to come up with a plan for how to move forward without Wayne. Darrius Heyward-Bey and T.Y. Hilton will certainly be part of it, but the trade deadline comes next week and the Colts have already shown a willingness to deal for offensive help in the wake of injuries this season when they acquired running back Trent Richardson after Vick Ballard went down for the year.

Indianapolis later lost running back Ahmad Bradshaw for the year as well and tight end Dwayne Allen is also on injured reserve, making a healthy number of unhealthy offensive pieces for the AFC South frontrunners.