UCLA defensive lineman Eddie Vanderdoes tore his anterior cruciate ligament in Saturday's win over Virginia and will miss the rest of the season, a source at the school told ESPN.com, confirming multiple reports.

The Bruins confirmed the injury Sunday night.

Vanderdoes, who is 6-foot-5, 305 pounds, was named one of the top 100 college football players this fall by ESPN.com. He injured his knee in the third quarter of UCLA's 34-16 win over the Cavaliers.

UCLA defensive lineman Eddie Vanderdoes was an All-Pac-12 honorable mention last season after recording 50 tackles, including 5½ for a loss, and two sacks. Cal Sport Media/AP Images

After the game, UCLA coach Jim Mora told reporters he thought the knee had "locked up on him."

Losing Vanderdoes is a significant blow to the Bruins defense, which boasted one of the strongest fronts in college football, with Vanderdoes alongside nose tackle Kenny Clark. Last year, Vanderdoes was an All-Pac-12 honorable mention after recording 50 tackles, including 5½ for a loss, and two sacks.

He led UCLA on Saturday with eight tackles, including two for a loss.

The No. 13 Bruins travel to UNLV on Saturday.