Donald J. Trump on Thursday accused Hillary Clinton of guiding a “global power structure” that has rigged the economy against the working class, language that some suggested echoed anti-Semitic themes.

Mr. Trump made the accusation in a speech in West Palm Beach, Fla., in which he also defended himself against several accusations of sexual harassment, published by The New York Times and others.

Early in the speech, he said that a global elite had “stripped” the United States of its wealth in order to line the pockets of corporate and political interests. “The Clinton machine is at the center of this power structure,” he said.

“We’ve seen this firsthand in the WikiLeaks documents in which Hillary Clinton meets in secret with international banks to plot the destruction of U.S. sovereignty in order to enrich these global financial powers, her special interest friends and her donors,” he said, referring to the group that has, most recently, published thousands of hacked emails from Mrs. Clinton’s campaign chairman.