Ramos and Isco set to miss trip to Valencia LaLiga - Valencia vs Real Madrid Both had featured in midweek

While Valencia have defensive issues of their own ahead of Saturday's encounter versus Real Madrid, the visitors will also be without two key men.

Neither Sergio Ramos nor Isco are due to make the journey east despite both starting in the midweek loss to Leganes and turning out for the part of Friday's training session filmed by the media.

Real have released a statement to confirm the nature of both players' injuries, Isco suffering from a hip injury on which he 'will continue to be assessed' as his absence clears the way even further for Zinedine Zidane to start with BBC up front.

Whereas Ramos, who had only returned from a hip issue for his first game of 2018 on Wednesday, has been hit by an oedema to cause a swollen left calf muscle.