It's been four and a half years since Lisa Irwin disappeared, but authorities are hoping a new, age-progressed photo of the girl could lead to a break in her case.

The new photo, released by the National Center for Missing and Exploited Children, shows what Lisa may look like now at the age of five.

Lisa was only 10 months old when she vanished on October 3, 2011 from her parent's Kansas City, Missouri home. Her parents, Deborah Bradley and Jeremy Irwin, told police the tot was take from their home while Bradley slept and Irwin was at work.

Her disappearance drew national attention along with sparking massive searches by thousands of law enforcement officers. Police have tracked down thousands of leads, but few clues have ever been found in the case. There have been several reported sightings of girls matching Lisa's description, one of the most recent being a young blonde girl found in a Roma camp in October 2013, but none has been a match to Lisa.

Related: Missing Baby Lisa: Is Debit Card Fraud a Clue?

Anyone with information regarding Lisa's disappearance is asked to call the Kansas City Police Department Tip Line at (816) 474-8477. The family says a $100,000 reward is still being offered by an anonymous donor for her safe return.