Land O'Lakes yellow American cheese is yellow from the natural coloring from the seed of the tropical annatto plant. That is the only difference between white American cheese and yellow American cheese. Now for the real answer: The true difference between white & yellow is only food coloring, its just a marketing ploy, white sells more in northern areas of the country, while the southerners like the standard yellow, there is no noticeble taste difference. Its a manufacters way to apeal to mozzarella, Swiss or provolone lovers.