A researcher says he has found where William Shakespeare lived in London and wrote some of his most popular works, including Romeo and Juliet and A Midsummer Night's Dream.

Shakespeare wrote some of his most popular works at his home in London, the researcher said. ( AAP: Dan Himbrechts )

Evidence shows Shakespeare lived in lodgings overlooking the graveyard of St Helen's Church in the 1590s, theatre historian Geoffrey Marsh said.

Mr Marsh cross-referenced a variety of official records to find the exact location, which is now home to an office block known as 35 Great St Helen's and just metres from skyscraper The Gherkin.

"The place where Shakespeare lived in London gives us a more profound understanding of the inspirations for his work and life," he told BBC News.

"Within a few years of migrating to London from Stratford, he was living in one of the wealthiest parishes in the city, alongside powerful public figures, wealthy international merchants, society doctors and expert musicians.

"The merchants had connections across Europe and the doctors were linked to the latest progressive thinking in universities in Italy and Germany.

"Living in what was one of the power locales of London would have also enhanced Shakespeare's status as he developed his career, sought a family coat of arms and planned to buy an impressive and expensive house in Stratford."