The Women in the World Summit is set to return in April with another starry lineup. Oprah Winfrey, Stacey Abrams, Brie Larson, Ashley Judd, Jill and Faith Soloway, Cindy McCain, Adwoa Aboah and Wanda Sykes, among others, are slated to appear at the 10th annual live media event, Women in the World announced Thursday. At the event, which is set to run April 10-12 at New York's Lincoln Center, Winfrey will be delivering the Summit's keynote address, wherein she will answer the event's guiding question: "Can women save the world?" Other topics that will be discussed in the event's live conversations include moving the #MeToo movement forward, fighting misinformation, keeping journalism alive, combating threats to the planet, advocating for same-sex love, resisting authoritarian and patriarchal powers and advancing women leaders.

For the first time, the summit will also feature a panel on comedy in today's cultural climate featuring Sykes, Rachel Bloom, Phoebe Robinson, Judy Gold and Amber Ruffin. “This year’s Summit is such a milestone event with our 10th anniversary; it is clearer than ever that the mission has met its moment," Women in the World and Tina Brown Live Media founder and CEO Tina Brown said in a statement. "The seeds we’ve planted as far back as 2010 in a small midtown theater have exploded into a global community of women of power and purpose.” Last year's summit featured speakers including Hillary Clinton, Viola Davis, Ronan Farrow, Sheila Nevins, Sen. Kirsten Gillibrand (D-NY) and Jameela Jamil. In a conversation with MSNBC's Joy-Ann Reid at the 2018 event, Davis discussed how women's experiences are improving in Hollywood: "Women are much more aggressive out there in terms of getting what they want. Now we are bold," she said. "We’re raising a defense fund for women so if they want to prosecute their predator, it’s there for them.”