The California Highway Patrol was investigating a report of roadway violence and possible shots fired on the northbound 241 toll road in Lake Forest and Mission Viejo on Tuesday night, according California Highway Patrol Officer Agustin Latosquin.

The incident occurred on the 241, between Los Alisos Boulevard and Portola Parkway, around 6:40 p.m. while the parties were stopped along the roadway, Latosquin said. Both parties left the scene.

According to a statement released by the CHP Wednesday, two men, one driving an older model pickup truck and another in a light-colored sedan, stopped along the toll road’s right shoulder and “became involved in an altercation.”

During the altercation, the pickup truck’s driver sustained a single gunshot wound and both drivers fled, according to the statement.

The driver of the pickup truck, described only as a “white male,” called police and paramedics while driving with a gunshot wound to his Irvine home. He was treated for his wound, which was believed to be non-life-threatening, Latosquin said.

The driver of the sedan, also identified as a “white male,” fled northbound on the 241. His whereabouts were unknown.

A SigAlert was issued for the two right lanes of the northbound 241, from just north of Los Alisos to Portola Parkway — about a mile — around 7 p.m. as investigators worked to preserve the crime scene and scour the area for evidence, Latosquin said.

Anyone with information about this incident can call the CHP Border Division’s Investigative Service Unit’s Investigator Kelly at 714-240-3752. Anyone who wants to submit anonymous tips can call Orange County Crime Stoppers at 855-TIP-OCCS (855-847-6227).

Contact the writer: 714-796-7802 or jsudock@scng.com