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MONTREAL — Canadian National Railway Co. says it will be forced to close “significant” parts of its Canadian network unless blockades impeding its rail lines are removed.

CN has halted more than 150 freight trains since Thursday evening, when demonstrators set up blockades in British Columbia and Ontario in solidarity with opponents of the Coastal GasLink pipeline project that crosses the traditional territory of the Wet’suwet’en First Nation in northwestern British Columbia.

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Via Rail said 157 passenger trains have also been cancelled, affecting 24,500 travellers on routes between Montreal and Toronto and Ottawa and Toronto.

The ongoing blockades sit near Belleville, Ont., and New Hazleton in B.C.’s northern interior while other demonstrations cropped up Tuesday in locations ranging from the Halifax port to the B.C. legislature.

Industry groups are also expressing concern about the shutdown as shipments to and from the U.S. and China are delayed or cancelled.