Hillary Clinton Hillary Diane Rodham ClintonButtigieg stands in as Pence for Harris's debate practice Senate GOP sees early Supreme Court vote as political booster shot Poll: 51 percent of voters want to abolish the electoral college MORE’s Democratic presidential campaign is hitting Donald Trump Donald John TrumpOmar fires back at Trump over rally remarks: 'This is my country' Pelosi: Trump hurrying to fill SCOTUS seat so he can repeal ObamaCare Trump mocks Biden appearance, mask use ahead of first debate MORE, describing the Republican's disastrous week as the "final meltdown" in a new ad.

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The attack ad, released Wednesday, is a take on the 1986 hit song "The Final Countdown," with the lyrics of the chorus changed to "it's the final meltdown."

The spot hits Trump on lewd remarks he made in 2005 about groping and trying to have sex with women, as well as the ensuing fallout between the Republican nominee and GOP leaders after video of his comments became public last week.

The spot includes footage of a CNN anchor saying that Trump is "reeling from criticism by his own party’s leadership."

It then focuses on Trump’s Twitter feud with Speaker Paul Ryan Paul Davis RyanKenosha will be a good bellwether in 2020 At indoor rally, Pence says election runs through Wisconsin Juan Williams: Breaking down the debates MORE (R-Wis.) after the video surfaced and shows the Republican nominee defending his comments as “locker room talk.”

It also highlights Trump’s threat during the last presidential debate to send Clinton to prison and the questions he raised about her health.

“Donald Trump appears to be in total meltdown,” another CNN anchor says.