A mum set to give birth to incredibly rare quadruplets has revealed how the coronavirus crisis has changed her world.

Natalee and Khan live with their daughter in Roebourne, a former gold rush town in Western Australia's Pilbara region, 1500km north of Perth.

Natalee used ovulation induction fall pregnant with Kiana, injecting medications to stimulate regular ovulation.

Hoping to give Kiana a sibling, the couple tried the same treatment – but got way more than they bargained for.

Mum Natalee is soon to give birth to quadruplets in coming months. (A Current Affair)

"Twins run in my family so I was happy with two, but not one part of me ever thought we would end up with four," Natalee said.

In Australia, the chances of having identical quadruplets is a staggering one in 11-15 million.

A Current Affair first interviewed the excited couple earlier this month, when they were already worrying about their babies' health, given the potential for complications.

Natalee said she was worried about the health of her new babies. (A Current Affair)

After the interview, the couple jetted off to the Cook Islands via New Zealand for one last holiday.

But then as the coronavirus crisis spun out of control, and borders shut down around the globe, the couple were stuck in New Zealand.

They have only returned to Western Australia this week, going straight into 14 days of self-isolation at Roebourne.

"This has come along and scared me all over again in a different way," Natalee told A Current Affair via Facetime.

The family is now in isolation after returning from New Zealand. (A Current Affair)

She's currently 17 weeks pregnant, so she has about 12 weeks to go before giving birth to four premature babies.

They had always planned to move to Perth ahead of the birth, but with the nearest medical facility currently 50km away from the couple in Karratha, Natalee's specialist wants her down south ASAP.

"From then on I will just be visiting the hospital for my appointments weekly, and after that, I don't know, I haven't even thought that far ahead," she said.

"Sad and scared, I just cannot believe how it's taken over the world, and for three months, family and my parents and everyone won't be able to meet my babies, and it's scary, really scary."

But she said she was thankful her husband and daughter were close by, and that she was still able to keep in touch with loved ones.

"We have amazing support from family and friends even if it is just through social media," she said.