CLEVELAND, Ohio — A federal grand jury in Cleveland charged 20 people in a case that involved hundreds of pounds of heroin, fentanyl and cocaine sent over the border from Mexico to the U.S. and distributed nationwide.

An indictment unsealed Tuesday says an organization led by a man in Mexico named Julian Aguirre-Aguirre, nicknamed “El Chocolate,” sent drugs to Northeast Ohio, as well as New York, Arizona, Louisiana and Georgia. Members sent drugs through the mail and in semi-trucks, and some members carried them into the U.S., the indictment states.

Participants used encrypted push-to-talk telephones to talk to each other and wired money to people in Arizona after drugs were sold, according to the U.S. Attorney’s Office.

The federal investigation into the organization, though not its breadth, was made public in January, when agents arrested five men in the Cleveland area who delivered 33 pounds of cocaine from Chicago. Agents seized the drugs after wiring up a house in Eastlake with recording devices and working with an informant to steer a car containing to the cocaine into the car’s garage, records say.

Three of the men jumped out of a second-story window and fled across the highway when agents descended upon a TownPlace Suites in Streetsboro. They hailed a Lyft, whose driver made it to Columbus before authorities arrested them there, according to court records.

The men arrested in Cleveland and Columbus were in contact with Aguirre-Aguirre, prosecutors said.

In addition, the U.S. Attorney’s Office says in a news release that Herman Fletcher and Nelson Becton distributed drugs for the operation in Ohio, and 14 others in Ohio helped.

Aguirre-Aguirre is not in custody, First Assistant U.S. Attorney Bridget Brennan said in an email.

The case is assigned to Senior U.S. District Judge Christopher Boyko.