A woman has been charged with the murder of two young sisters who were found dead in a car at Logan, south of Brisbane, after being exposed to "extreme heat".

Queensland police and paramedics were called to a home at Waterford West shortly after 1:30pm on Saturday and found the pair, aged one and two, unresponsive in a "hot" car.

Late on Saturday night Queensland Police released a statement saying they had charged a 27-year-old Waterford West woman with two counts of murder following an investigation into the girls' deaths.

Police said the woman was known to the two girls but did not provide any further details on their relationship.

Officials were called to a home at Waterford West after 1:30pm. ( ABC News: Rachel Riga )

Detective Inspector Mark White, from the Logan Child Protection and Investigation Unit, said the Queensland Ambulance Service (QAS) made attempts to revive the two children, but both were declared dead at the scene.

"The two children exhibited evidence of being exposed to extreme heat," he said.

"It's just a very, very tragic incident that has occurred. They were very young children."

Space to play or pause, M to mute, left and right arrows to seek, up and down arrows for volume. Watch Duration: 48 seconds 48 s Police are investigating how the children died.

Detective Inspector White said support was being provided to staff involved in the investigation.

"One of our priorities today, in addition to conducting the investigation, is the wellbeing of our staff," he said.

"It's very, very tragic and can be quite a distressing scene to be confronted by."

The woman is scheduled to appear in Brisbane Magistrates Court on Monday.