Maria Bueno, who won three Wimbledon singles titles and four at the United States Nationals and was ranked No. 1 in the world four times in the last years of tennis’s amateur era, died on Friday in São Paulo, Brazil. She was 78.

Her death was confirmed on her website. She had been treated for oral cancer that was diagnosed in 2016.

Bueno was one of the greatest women’s tennis players of her time and was hailed as a celebrity in her home country, Brazil. She captured 19 Grand Slam titles — seven in singles, 11 in doubles and one in mixed doubles — between 1958 and 1968 and was inducted into the International Tennis Hall of Fame in 1978. She won 589 tournaments, her website reported.

Bueno also reached the singles finals at the Australian Open and the French Open, where a minute of applause in her memory preceded the women’s singles championship final on Saturday.