is a dessert topping mentioned inand. The topping is a mixture of whipped cream and nitrous oxide (commonly known as "laughing gas", hence the name).

The product is advertised on the radio in GTA: Vice City with the tagline "Makes dessert funny". Apparently, Florida Congressman Alex Shrub legalized Giggle Cream, resulting in the deaths of 23 people, though he claimed that "some of them probably deserved it". It was later banned by the FDA.

In GTA IV, Giggle Cream can be seen being sold illegally on yourmexicandoctor.com where the deaths in the 1980s are mentioned.

Trivia