BREAKING NEWS : New Studies Emerging That Confirms The Coronavirus Is Mutating And Becoming More Virulent

Source : Thailand Medical News Feb 05, 2020 8 months ago

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coronavirus

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coronavirus

coronavirus

coronavirus

coronavirus

coronavirus

coronavirus

coronavirus

Thailand Coronavirus

Initial comments by many so called experts including some from WHO and The US CDC saying that theis nothas now been gradually proved to be wrong.On the 27Of January, Dr Nancy Messonnier, head of respiratory diseases at the Centers for Disease Control and Prevention (CDC) commented thatwas not. (Source: Medical Express)Dr Kristian Andersen, an infectious-disease researcher at Scripps Research in La Jolla, California on the 31of January also made a comment that theis not capable of mutating to become more potent. (Source: The Nature)Many other so called experts also made similar comments during the last two weeks.However, many new research studies by Chinese researchers and also new developments are confirming a different scenario.Virology specialists from the Institut Pasteur of Shanghai in two different studies have confirmed that theisand becoming more virulent.The first has already been published in the journal of National Science Review on the 29of January (refer to url link below) while a second is to be published this week, also in the same journal.The virology researchers studying a cluster ofinfections within a family in the southern province of Guangdong said the genes of the virus went through some significant changes as it spread within the family.Viruses mutate all the time, but most changes areor “silent”, having little effect on the way the virus behaves. Others, known assubstitutions, can alter biological traits, allowing them to adapt to different environments.Twochanges took place in the viral strains isolated from the family, according to the study by Professor Cui Jie and colleagues at the Institut Pasteur of Shanghai.This case indicated “viral evolution may have occurred during person-to-person transmission”, they wrote in the paper published in the journal National Science Review on 29 January. (the url link for that study is found below)In the second study involving another group of patients from Hubei, the team also found significantsubstitutions taking place and confirmed that the virus is indeedbecoming more potent and virulent.In different study by Dr Fang Li from the University of Minnesota that was published in the Journal of Virology, on the 29Of January 2020 (url link found below), lead researcher Dr Fang Li, warned after studying the genome of the virus that their research data alarmingly predicts that a single mutation (at a specific spot in the) could significantly enhance the Wuhan's ability to bind with human angiotensin-converting enzyme-2 (ACE2) receptors to become extremely potent and deadly.She further added, “For this reason, Wuhanin patients should be closely monitored for the emergence of novelat the 501 position in its, and to a lesser extent, the 494 position, in order to predict the possibility of a more serious outbreak than has been seen so far.”According to Dr Li, these type of” oris easy to occur considering the nature of the virus genomic structure and characteristics.Other experts are also saying that theis not only “fast learning and adapting” it is beginning to exhibit signs that it is improving its mode and potency of transmissions and also its potency in the human body even to the stage of preventing antibody reactions.A Chinese researcher at Wuhan Institute of Virology of the Chinese Academy of Sciences who wished to remain anonymous due to security reasons said “ efforts to develop a vaccine and also find treatments using antivirals will be hampered by thepotency and. Already we are witnessing resistant to some of the initial antivirals we had used and that too in a very short time. We are dealing with something here that is going to be far more challenging that what most people can imagine.: Read also: https://www.thailandmedical.news/news/largest-meta-analysis-of-sequenced-genomes-of-the-coronavirus-reveals-a-new-subtype-has-emerged For accurate updates about theor thescenario, keep on checking at: https://www.thailandmedical.news/articles/coronavirus References:Evolutionary Perspectives on Novel Coronaviruses Identified in Pneumonia Cases in China , Xiaoman Wei, Xiang Li, Jie CuiNational Science Review, nwaa009, https://doi.org/10.1093/nsr/nwaa009 Published: 29 January 2020Yushun Wan et al, Receptor recognition by novelfrom Wuhan: An analysis based on decade-long structural studies of SARS, Journal of Virology (2020). DOI: 10.1128/JVI.00127-20