By Will Vandervort | October 3, 2018 7:50 pm ET

Multiple sources have confirmed to The Clemson Insider that former Clemson running back C.J. Fuller has passed away on Wednesday. He was 22 years old.

Sources have confirmed to TCI that Fuller passed away due to complications from a seizure.

Fuller played a big role in Clemson’s national championship team in 2016, catching touchdown passes against Ohio State in the Fiesta Bowl and against rival South Carolina in the regular-season finale that year.

He also had a huge kickoff return in the national championship game against Alabama for the Tigers that allowed them to begin the game-winning drive in good field position.

Fuller left the program following the 2017 season to transfer to another school.

Last year, Fuller rushed for 217 yards and scored three touchdowns for the Tigers. He began the season as the starter and started three games in 2017.

Prior to last year, he totaled 382 rushing yards and a touchdown on 89 carries. He also had 11 career catches for 106 yards and two touchdowns.

Fuller played in 44 games for the Tigers during his three-year career at Clemson.