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WASHINGTON — President Barack Obama announced the re-establishment of diplomatic relations with Cuba on Wednesday and declared an end to America’s “outdated approach” to the communist island in a historic shift aimed at ending a half-century of Cold War enmity.

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“These 50 years have shown that isolation has not worked,” Obama said in remarks from the White House. “It’s time for a new approach.”

As Obama spoke to Americans, Cuban President Raul Castro addressed his own nation from Havana, saying that while the two countries still have profound differences in areas such as human rights and foreign policy, they must learn to live together “in a civilized manner.”

Wednesday’s announcements followed more than a year of secret talks between the U.S. and Cuba, including clandestine meetings in Canada and the Vatican and personal involvement from Pope Francis. The re-establishment of diplomatic ties was accompanied by Cuba’s release of American Alan Gross, who had been imprisoned for five years, and the swap of a Cuban who had spied for the U.S. for three Cubans jailed in Florida. Gross spoke with Obama from the plane carrying him back to the U.S.