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Wanted: brave, possibly foolhardy colleague for mad old scientist.

Must have: sense of humour, yearning for adventure, belief in good of mankind.

Do not apply if you’re looking for a nine-to-five role or suffer from a nervous disposition.

Not sure how many would answer a job ad like the one above, but the time has come for some bright hope to step up, as Jenna-Louise Coleman is leaving the Tardis and her role as Clara, possibly at Christmas.

It’s been quite a ride for Clara, firstly alongside Matt Smith’s handsome young Timelord and now teaming up with Peter Capaldi’s slightly more eccentric but nonetheless engaging rendering of the Gallifreyan.

With such a massive role at stake, the bookies have gone into overdrive, selecting their favourites to play the Doctor’s long-suffering companion next.

And, being the mischief-makers we are, we’ve gone through a list of likely Welsh lovelies and compiled our nominees for who could be saying ‘bore da’ to the Time Lord next.

Check out the gallery for the faces to watch.

Game Of Thrones star Rose Leslie, 27, is the favourite to become the Doctor’s next companion, according to the latest odds from Ladbrokes.

Odds of her stepping out of the TARDIS are currently at 14/1 when – or rather if – Jenna Coleman leaves, which is rumoured to be part of the Christmas storyline.

The betting company also have 16/1 for Chris Addison and Peter Capaldi – who were both in The Tick Of It – join forces once again, and the same odds are on offer for Karen Gillan – who was Amy Pond during Matt Smith’s Tardis tenure – to make a shock return to the show.

Jessica Bridge of Ladbrokes said: “Jenna’s exit came as a big shock, but punters don’t seem to mind too much and are in the thick of it placing bets on a Capaldi-Addison reunion.”

Ladbrokes latest odds

14/1 Rose Leslie

16/1 Chris Addison

16/1 Karen Gillan

16/1 Jessica Brown-Findlay

16/1 Kerrie Hayes

20/1 Alfie Allen

20/1 Jack Gleeson

20/1 Maisie Williams

20/1 Alex Kingston

20/1 John Barrowman

25/1 Sophie Turner

25/1 Romola Garal

25/1 Nadine Marshall

25/1 Billie Piper

25/1 Rebecca Front

33/1 Thomas Sangster

33/1 Isaac Hempstead-Wright

33/1 James Corden

33/1 Catherine Tate

33/1 Vicky McClure

33/1 Simon Amstell

33/1 Natalie Dormer

40/1 Sandra Dickinson

50/1 Joanna Scanlan

50/1 Emily Watson

66/1 Daniella Westbrook

66/1 Emilia Clarke

100/1 Lena Headey

100/1 Kelly Brook

100/1 Tulisa Contostavolos

200/1 Millie Mackintosh

500/1 Kim Kardashian

The story first appeared in The Mirror