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Prior sexual stimulation is required for experiencing the effect of Kamagra. Sildenafil is a potent PDE 5 inhibitor. It inhibits the action of PDE-5 enzyme present inside the penile region in large quantities. This inhibitory action stops the degradation of an endogenous chemical called cGMP. This substance helps in the relaxation of smooth muscles and dilation of the blood vessels inside the penile region. The dilated blood vessels boost the amount of blood reaching the penile organ.

A sufficient quantity of blood supply produces a firm and strong penile erection necessary for satisfactory sexual intercourse. The action of Kamagra can be seen within 30 to 60 minutes post oral administration. Its effect lasts for about four to five hours on average. Kamagra is sold in doses such as 25mg, 50mg, and 100mg. The usual starting dose is 50mg. However, the dose can be increased or decreased depending on the severity of the condition, medical history and response to the treatment.