The most common risk factor for serious disease is old age. Heart disease, cancer, stroke, neurological conditions, diabetes — all increase radically with advancing years. And the older a person is, the more likely he or she is to have multiple chronic illnesses.

Some scientists hope one day to treat all of them at once — by targeting aging itself.

Humans aren’t built to last forever. The oldest person on record was Jeanne Calment, a Frenchwoman, who died in 1997 at the age of 122. In 2040, the average life span for people in Spain, projected to pass Japan as the country with the longest-lived citizens, will reach about 86 years.

There is considerable dispute, however, over how long humans might live under optimal circumstances. In 2016, a team of scientists declared the upper limit to be 115 years. But in June, researchers reviewing death rates among elderly Italians suggested that there may be no limit at all.

In animal studies over the last few decades, scientists have begun to understand the specific cellular and molecular processes that cause the deteriorations of old age.