MINNEAPOLIS -- Brett Favre has become something of a medical expert through the years, a quarterback who has minored in pain management as he has put together a streak of consecutive starts that stands among the most impressive records in all of sports.

Yet even a 41-year-old who has played 20 seasons in the league still can learn something new, and Favre is now faced with a pain and an injury that he's never felt before.

Brett Favre left Minnesota's game during the first series after taking this hit from Buffalo's Arthur Moats on his first pass attempt of the day. AP Photo/Hannah Foslien

Favre sprained the sternoclavicular joint in his throwing shoulder after getting crunched by Bills linebacker Arthur Moats on Sunday, an injury that leaves the Minnesota Vikings quarterback unsure of whether he will be able to start his 298th straight regular season game next week.

"If we were talking ankles or elbows, thumbs or something like that, I would probably be a little more up to date on how to deal with it," Favre said after the Vikings beat the Bills, 38-14. "First time in 20 years I have ever done anything like that, so it is kind of surprising."

The SC joint is located where the collarbone meets the breastbone. The more common shoulder injury for athletes is an AC joint sprain. According to Harvard Health Publications, SC joint sprains occur most often "when a driver's chest strikes the steering wheel during an auto accident, or when a person is crushed by an object."

For Favre, it was the latter case.

On the third play of the game Sunday, Moats came flying off the right edge and blindsided Favre just as he was about to throw a pass. The 250-pound linebacker flattened Favre, landing on top of him as he drove the quarterback into the turf.

The pass fluttered and was intercepted by Drayton Florence, and Favre was slow to get up. He staggered to the sidelines and was replaced by Tarvaris Jackson on the next series.

"He took a pretty good lick in the back as he was coming back and getting ready to throw the ball," said running back Adrian Peterson, who picked up the slack with 107 yards and three TDs. "I know that didn't feel good. I don't know the extent of his injury or what's wrong with him, but obviously for him not to come back in, it must've been painful."

Favre headed to the locker room with athletic trainer Eric Sugarman for an X-ray, which revealed no broken bones and returned to the sideline later in the second quarter.

During the game, the team called his return questionable, but Favre said there was no way he could have been effective if he had to go back in the game.