A man has been taken into custody after driving his car on the wrong side of the road and into the path of oncoming traffic outside the Queensland Police Service Headquarters in Brisbane.

Police said the man was driving the wrong way along Roma Street about 4pm during peak hour traffic when he parked the car outside their building, facing oncoming traffic.

Police suspect the driver was under the influence of alcohol. Credit:Queensland Police Service

Police officers took the "suspected drink driver" into custody where he was assisting with inquiries.

A police spokesman said that the man's behaviour suggested it was "possible that he is intoxicated with some substance".

Roma Street was closed while police moved the car off the road.

Police said early media reports that the car had tried to drive up the stairs at the front of headquarters were not true.

A car did ram the police building on January 29, with a man allegedly trying to reverse his white Ford Territory up the front stairs.