Federal agents have been called in to investigate after the local sheriff's department pulled over a truck in South Carolina.

A pickup truck was stopped by sheriff's deputies on Interstate 85 in Anderson County on Monday.

Sheriff Chad McBride said he could not reveal what deputies found in the truck because Homeland Security had taken over the investigation.

McBride confirmed the traffic stop was not related to illegal drugs, the Independent Mail reports.

A pickup truck was stopped by sheriff's deputies on Interstate 85 in Anderson County, South Carolina on Monday

'We made a traffic stop, and the persons that were stopped were of interest to the feds,' McBride said. 'Stop was turned over to them.'

The stretch of highway is between Charlotte, North Carolina and Atlanta, Georgia. Authorities have managed to uncover several major crimes on the highway in recent years.

Local man, Antonio Crawley, was arrested in January and sentenced to life in prison for his role in a long-running drug trafficking ring.

There was also a number of human trafficking cases last year, which authorities say is because of the I85 and its proximity to Atlanta and Charlotte.

Authorities have not released any further details about Monday's investigation.