Victorian Greens MP Lidia Thorpe, who looks to have lost the seat of Northcote just one year after winning it in a by-election, says the party needs to seriously review its campaign after suffering a statewide swing against it.

Key points: Greens suffered swing against it in Victorian election

Greens suffered swing against it in Victorian election It had hoped to win more inner-city seats and gain balance of power

It had hoped to win more inner-city seats and gain balance of power Party leader Samantha Ratnam defended campaign but said there would be a review

The Greens are expected to lose the seat in Melbourne's inner north as well as four of its five Upper House seats, according to the latest information from the ABC's election computer.

They were also battling to retain the inner-city seat of Prahran, where incumbent MP Sam Hibbins was locked in a tight three-way contest with the Liberal Party and Labor.

The party went into the election hoping to win the balance of power and even negotiate a ministry in a minority government, but on current numbers, it suffered a swing of 1.6 per cent against it.

While Ms Thorpe was yet to officially concede defeat in Northcote, she said the election had not produced a good result for the party.

"We need to have a good look at ourselves and have a review of what this election has done to our party, losing quite a considerable amount of Greens members," she told ABC Radio Melbourne.

The Greens were plagued by negative press surrounding a number of their candidates during the campaign, including one who was accused of serious sexual misconduct.

They also defended their candidate for Footscray, Angus McAlpine, after it was revealed he rapped about condoning date rape, drug use and domestic violence.

One of Ms Thorpe's staffers also attracted media criticism over a number of tweets he posted about pornography and sexual assault.

Ms Thorpe accused Labor of running a "dirty campaign" against her in Northcote, but conceded her campaign was hindered by bad press generated by party scandals.

"I think that the news on the Greens at that time, the number of media articles of what's going on in the Greens, didn't help," she said.

"I think that we need to seriously look at that, we need to have an internal review of this election.

"We need to be better at our candidate-selection processes through probity and we need to have a look at our resource allocation."

When elected last year, Ms Thorpe became the first Aboriginal woman in Victoria's Parliament.

"It's a shame that there won't be an Aboriginal voice in Parliament, we'll go back to the tokenistic gesture of representation of Aboriginal people in the Parliament," she said.

Lidia Thorpe said she is saddened there are no longer any Aboriginal MPs in the Parliament. ( AAP: Joe Castro, file photo )

The loss of the seat is a huge blow to the party, who hailed the 2017 victory as "just the beginning" of a Greens rise in Victoria.

Greens call for Upper House reform

Speaking to ABC Radio Melbourne, Greens leader Samantha Ratnam said the party would review the many "challenges" it faced during the campaign.

But she did not nominate any internal issues leading to the disappointing result.

"We ran a really big campaign, knocked on 160,000 doors, we had 6,000 volunteers out at voting centres, I was really proud of the platform we put forward together," she said.

"Of course there were challenges over the last few weeks and we'll be reviewing those things post-election to improve a number of things.

"But you know, our vote held up despite a huge Labor swing and that's really important to remember."

Dr Ratnam denied this year's election marked the start of the decline of the Greens in Victoria and repeated her calls for reform of the Upper House voting system.

Current projections have 10 minor-party candidates entering the Legislative Council, off the back of complex preference deals.

Fiona Patten looks likely to have lost her Upper House seat. ( Supplied )

Among those to lose their spot will be the Reason Party's Fiona Patten, who was influential in the introduction of assisted-dying laws and the safe-injecting-room trial last term.

When asked about Ms Patten's future, Premier Daniel Andrews indicated she may still have a role in shaping the state.

"I think that is a loss for the Parliament, she is a very good person, who lives her values and worked very hard these last four years," he said.

"She'd have not only very good references from many of the ministers in my Government who have worked closely with her, but just her record tells you she's someone who could play all manner of different roles.

"I look forward to speaking with her personally in the next few days and if she's interested, I'm sure she could find some different roles for her to play in order to make the place fairer and stronger."

On Sunday, Ms Patten said she was "disappointed" by the wave of micro-parties likely to be elected this year, which she attributed to preference negotiations managed by so-called "preference whisperer" Glenn Druery.

As the Greens, and to a larger degree the Liberal Party, deal with the fallout from their disastrous elections, Mr Andrews is considering the make-up of the new Labor Cabinet, as a number of new faces join the Parliament.

Minister Natalie Hutchins said she has decided not to recontest her position in Cabinet, following the death of her husband last year.

Ms Hutchins, whose portfolios included women, Aboriginal affairs, and the prevention of family violence, said she wanted to focus on her family.

"I am proud to have been a part of a government that committed to treaty with the states' traditional owners, improved conditions for vulnerable workers, established Respect Victoria and ensured women have an equal voice in everything it does," she said in a statement.

She said she would continue to serve the Government as a backbencher.