The Story Bridge will be closed and rented out up to four times a year under a Queensland government and Brisbane City Council plan to host major events.

Premier Campbell Newman and Lord Mayor Graham Quirk have declared the Story Bridge "open for business".

Brisbane's Story Bridge will be closed up to four times a year for major events.

Currently the Story Bridge is only closed for Riverfire – the city's fireworks display staged to mark the end of the Brisbane Festival.

But organisers could apply to close the bridge for major events such as fun runs, a cycling event or a significant cultural event.