Opposition Leader Bill Shorten collided with protesters for the second time in as many days after activists stormed the stage to derail his opening address to Labor’s national conference.

About half a dozen protesters calling on Labor to stop the Adani coal mine in Queensland and close the offshore processing centres on Manus Island and Nauru had to be dragged off stage by security at the Adelaide Convention Centre on Sunday morning.

Protesters take to the stage as Bill Shorten delivers his opening address to Labor's triennial national conference. Credit:Alex Ellinghausen

Some of the protesters were dressed in "It’s Time" T-shirts, referencing Labor Prime Minister Gough Whitlam’s famous 1972 campaign theme song. The group carried a banner on stage that read: “ALP - stop playing politics with peoples lives - #closethecamps."

As the party faithful booed, heckled and yelled "where’s security?", Mr Shorten quipped: "I’ve waited as Opposition Leader for the next election for five years and two months, and if I've got to wait a couple of more minutes, I just will."