Dolores greets Roderick with a gesture to remind him of the conversation they had in the first episode of this season: this can all be a simulation or a product of nucleus accumbens. He claimed that everything we're living might not be real, that it could all be a simulacrum. She attributed his feeling to nucleus accumbens, a group of neurons that transmit to the brain pleasurable and motivational information (sex, addictions and religious beliefs, for example).