Did you hear about the two bed bugs that met in the mattress? They were married in the spring.

It's an Ellen DeGeneres joke but if you have ever been a victim of cimex lectularius and rows of terrible itching bites you'll know it's no laughing matter.

Not picky: Head lice along with bedbugs are becoming tough to exterminate.

A new study to be published early in the new year conducted by the Department of Medical Entomology, Westmead Hospital and the University of Sydney reveals that the common bed bug in NSW has developed resistance to insecticides.

Report co-author Cameron Webb, medical entomologist with University of Sydney and NSW Health Pathology, says bed bugs don't discriminate about where they set up residence and that includes some top Sydney hotels.