The Windows era at Microsoft, long in eclipse, is officially history.

Microsoft said on Tuesday that it was splitting up its Windows engineering team and that the leader of its Windows business was leaving.

The moves, analysts said, were part of a reorganization intended to accelerate Microsoft’s emphasis on newer, faster-growing businesses like cloud computing and data-fueled artificial intelligence. That shift, they noted, has been underway since Satya Nadella became chief executive in 2014.

In an email to employees, Mr. Nadella cited the central role of cloud computing and the advances in artificial intelligence — and their potential across all the company’s products. The organizational overhaul, Mr. Nadella wrote, “enables us to step up to this opportunity.”

Terry Myerson, 45, executive vice president of Microsoft’s Windows and devices group, will be departing. In a separate email to employees, Mr. Myerson said that he supported the company’s evolution under Mr. Nadella.