Reviews

The following paired reviews from Science and Science Translational Medicine discuss basic research advances in the ecology, metabolism, and microbial-host immune interactions of the gut microbiota and translation of this knowledge into new treatments to boost immune defense, combat disease, and improve nutrition.

Science The Application of Ecological Theory Toward an Understanding of the Human Microbiome Ecological theory can be used to gain a better understanding of the diversity, interactions, and dynamics of human gut microbial communities. Science Translational Medicine Microbiota-Targeted Therapies: Taking Advantage of Ecology Insights from ecology will help to drive the development of microbiota-targeted therapeutics.

Science Host-Gut Microbiota Metabolic Interactions Direct chemical interactions between the gut microbiota and the host comprise a series of metabolic axes that connect the gut and liver with other organs. Science Translational Medicine Therapeutic Modulation of Microbiota-Host Metabolic Interactions Abnormal microbial-host metabolic interactions underlying disease provide new targets for therapeutic intervention.