A dog owner is set to be reunited with her beloved pooches three years after they went missing in Adelaide.

Trinity Grange, who lives in Melbourne, left her dogs with a friend in Adelaide while she went on holiday to Bali in 2012.

Rana and Honeybear disappeared without a trace and Ms Grange did not see them again.

On the weekend, the two dogs were handed in to the Animal Welfare League (AWL) at Wingfield in Adelaide's northern suburbs.

Ms Grange had continued to update their microchipping details and as a result was contacted.

The dogs will be flown to Melbourne on Tuesday and reunited with their owner.

"I love these dogs so much that I grieved for two years and eventually I said to myself, you have to stop crying Trinity, you're never going to see them again," Ms Grange said.

"So I went and got a giant tattoo in the hope that the physical pain would stop me thinking about the emotional pain.

"Now I've got a massive tattoo of homage to these dogs that I'm going to have anyway."

AWL spokesperson Sabine Kloss said the reunion illustrated the importance of microchipping pets and keeping information updated.

"This is truly a happy outcome to a three-year nightmare for Trinity as she desperately tried to find her beloved dogs," she said.

"She never gave up hope and always kept her microchipping details updated, which allowed us to contact her immediately when her dogs were finally brought in.

"It really goes to show the importance of microchipping your animals and maintaining that information."