The big one is in the books. After five-plus years of waiting, Floyd Mayweather-Manny Pacquiao is over and done with after Mayweather coasted to a unanimous decision this past Saturday night at the MGM Grand in Las Vegas in one of the biggest fights in boxing history -- and one of the biggest duds.

Pacquiao, who came into the fight with an injured right shoulder, is due to have surgery to repair his torn right rotator cuff and will be out for about a year. A rematch with Mayweather is probably not out of the question and would still be big, even if nowhere near what Saturday's fight was.

"There will always be a big fight. There are a lot of great fighters and guys out there who are interesting to the public. After Manny and Floyd depart, there will still be big fights, believe me."

But now that Mayweather-Pacquiao is part of history what are some other fights fans would surely look forward to down the road?

"There will always be a big fight," Top Rank's Bob Arum, Pacquiao's promoter, said. "There are a lot of great fighters and guys out there who are interesting to the public. After Manny and Floyd depart, there will still be big fights, believe me."

Here are five possible big bouts -- not in the Mayweather or Pacquiao category -- to think about, and one bonus fight for down the road in a few years:

Miguel Cotto-Canelo Alvarez is a classic Puerto Rico vs. Mexico fight, one of the best rivalries in boxing. AP Photo

Miguel Cotto vs. Canelo Alvarez

Other than fights involving Mayweather or Pacquiao, Cotto-Alvarez looms as boxing's biggest fight. And the good news is we are likely to see it later this year on HBO pay-per-view.

Cotto-Alvarez is a classic Puerto Rico-versus-Mexico fight, and that is one of the best national rivalries in boxing. The match also looks good on paper in terms of providing a crowd-pleasing bout for high stakes.

Cotto (39-4, 32 KOs), 34, a future Hall of Famer, is winding down his great career. He is the first Puerto Rican fighter to win world titles in four weight classes, including winning the middleweight world championship last June by 10th-round knockout of Sergio Martinez. Alvarez (44-1-1, 31 KOs), the 24-year-old Mexican star, is a former unified junior middleweight titleholder whose only loss came by decision to Mayweather in 2013 in the biggest revenue fight in boxing history (until the Mayweather-Pacquiao numbers come in and shatter it).

For the fight to happen, Alvarez and Cotto have business to take care of. Alvarez will face big banger James Kirkland on Saturday night (HBO, 9 ET) at Minute Maid Park in Houston. Cotto makes his first middleweight title defense, against former titlist Daniel Geale, of Australia, at Barclays Center in Brooklyn, New York, on June 6 (HBO). As long as Alvarez and Cotto come through, they have a deal in place for a fall showdown.

If heavyweight champ Wladimir Klitschko wants t hold of the titles, he'll have to take on from Deontay Wilder. Scott Heavey/Getty Images

Wladimir Klitschko vs. Deontay Wilder

Klitschko (64-3, 54 KOs) is the heavyweight world champion, and a dominant one at that. He has made 18 consecutive title defenses (third-longest streak in division history), has held the title for a little over nine years, has not been in a competitive fight for more than a decade and is one of the best heavyweight champions in boxing history.

Although Klitschko is 39 now, he has not appeared to be slowing down at all. But before he retires, he would like to win the one alphabet belt he does not already own -- the same one his older brother, Vitali Klitschko, held before vacating it upon his retirement at the end of 2012.

Wilder (33-0, 32 KOs), a 2008 U.S. Olympic bronze medalist (the last American man to win an Olympic boxing medal), has it.

The heavyweight division has not had a truly big-time fight in a long time and this would be it. Klitschko and Wilder, who won the belt in January with an excellent performance in a lopsided decision against Bermane Stiverne, have both expressed interest in the fight.

They are both dynamic punchers and both have had people question their ability to take a punch, so it could be very, very interesting. They are also familiar with each other as Klitschko brought Wilder into one of his training camps to spar. Politically, it's a hard fight to make because Klitschko has an HBO contract and Wilder is aligned with adviser Al Haymon, whose fighters are barred from HBO. But where there's a will, there's a way. So it could happen, albeit Klitschko is likely to first make a mandatory defense against Tyson Fury and Wilder is due to make his first defense in June, possibly against Eric Molina.

An Adonis Stevenson-Sergey Kovalev fight could decide who's the light heavyweight king. Reuters, Getty Images

Adonis Stevenson vs. Sergey Kovalev

For more than a year, boxing fans have wanted the light heavyweight summit meeting between these big punchers. Stevenson, who is the lineal champion, owns one alphabet belt, and Kovalev, the best 175-pounder on Earth, owns the other three major belts.

They were supposed to fight each other last fall, but that was before Stevenson (26-1, 21 KOs), 37, of Montreal, walked away from the deal to jump from HBO to Showtime and instead wound up facing poor opposition. Kovalev (27-0-1, 24 KOs), 32, of Russia and living in Los Angeles, meanwhile, has taken on the best light heavyweights available to him, as he has beaten Bernard Hopkins (decisively on points in a November unification fight) and former champion Jean Pascal (by eighth-round knockout in March) in his past two fights.

Kovalev's team campaigned to be made mandatory for Stevenson's belt, and the request was granted, an unusual move for a sanctioning body to rank another organization's titleholder. But it was good for boxing and it seemed as though it would help the fight get made even if they had to go to a purse bid rather than negotiate. But it was too good to be true. Citing a contract with HBO, Kovalev's camp, which had accused Stevenson of running for the past year, said it would not participate and would negotiate only if the fight would be on HBO, which was a nonstarter. So that is where we stand -- with neither man having a marquee opponent on deck and a fight between them seemingly as far away now as it was when Stevenson bailed last year.

But there is always hope that they will realize it's still the biggest, most lucrative fight for either man and they will somehow find a way to get it done.

AP Images, Getty Images

Terence Crawford vs. Lucas Matthysse

Style-wise, this one can't miss. Crawford, the 2014 ESPN.com fighter of the year, is an outstanding boxer with good power, but as slick as he can be, Crawford is not afraid to mix it up. Matthysse is a huge puncher who likes to brawl but is capable of boxing if necessary. Both have been in some crowd-pleasing fights and are among the best junior welterweights in the world.

The 27-year-old Crawford (26-0, 18 KOs), of Omaha, Nebraska, vacated his lightweight world title and moved up to junior welterweight to knock out Thomas Dulorme in the sixth round on April 18 in Arlington, Texas, to win a vacant belt.

On the same HBO-televised card, but in Verona, New York, Matthysse (47-3, 34 KOs), 32, of Argentina, engaged former titlist Ruslan Provodnikov in a hellacious battle that stands as the 2015 fight-of-the-year front-runner. Matthysse came out on top in a very competitive fight, winning a majority decision. There is a reason HBO had both bouts on the same telecast -- because the suits there know what a great fight Crawford against whomever won the other bout would be. It was Matthysse, who by winning, stands to become Crawford's mandatory challenger.

It is a makeable fight politically for various reasons. Top Rank, Crawford's promoter, and Golden Boy, Matthysse's promoter, are now more than happy to do business with each other following a long cold war. Also, both fighters are aligned with HBO. It would be a surprise if they fought each other in the next fight, but down the road a fight or two? Yes, please.

Andre Ward is a super middleweight, but Gennady Golovkin would be willing to go up in weight to face him. US TODAY Sports

Andre Ward vs. Gennady Golovkin

The potential fight has been talked about by fans for more than a year as something to see down the road, and that road is getting closer it would seem.

Ward (27-0, 14 KOs), 31, of Oakland, California, is a super-talent. He was a 2004 U.S. Olympic gold medalist and was regarded by many as the second-best fighter in the world behind Mayweather until putting himself into a long layoff because of his issues for his former promoter. But the super middleweight champion will end a 19-month layoff on June 20 by taking on England's Paul Smith in a tune-up fight. Now that his promotional situation is ironed out -- he signed with Jay Z's Roc Nation Sports in January -- he hopefully will get on a regular schedule. There is no obvious opponent for him at 168 pounds, and Ward has not yet committed to moving up to light heavyweight, so he needs a big-name opponent.

That is where Golovkin (32-0, 29 KOs), 33, a 2004 Olympic silver medalist from Kazakhstan now living in Los Angeles, comes in. Golovkin, himself a pound-for-pound contender, is also in dire need of a of an A-level dance partner, since none of the top opponents have been willing to fight him.

GGG, a wrecking machine middleweight titleholder, is scheduled to make his 14th title defense on May 19 when he will face Willie Monroe Jr. Assuming Golovkin and Ward both win, there is no reason their teams shouldn't at least discuss a plan to bring them together sooner than later. Politics won't be an issue, as Roc Nation Sports and Golovkin promoter, K2 Promotions, have no issues doing business together and both fighters are associated with HBO, even though Ward's next bout will be on BET.

For what it's worth, Ward and Golovkin, who has said he would have no issue moving up in weight, have mentioned each other as possible opponents.

Fight fans would love to see Felix Verdejo square off with Vasyl Lomachenko. Getty Images

Felix Verdejo vs. Vasyl Lomachenko

Granted, this one is way down the road if it ever happens, but it looks like a great one in the crystal ball.

Verdejo (17-0, 13 KOs), a 21-year-old lightweight and 2014 ESPN.com prospect of the year, was a 2012 Puerto Rican Olympian and has the look of a future star. He can fight, and he is already a popular attraction thanks to the passionate Puerto Rico fans.

Top Rank has been grooming him for stardom, and he will make his HBO debut on June 13, the eve of the annual Puerto Rican Day parade in New York at the Theater at Madison Square Garden. It figures to be the first of many MSG appearances. Eventually, Verdejo, if he develops like everyone believes he can, will be a pay-per-view attraction. Think Cotto and Felix Trinidad.

Lomachenko (4-1, 2 KOs), 27, was a 2008 and 2012 Olympic gold medalist for Ukraine and is one of the greatest amateurs in history. He is so good that he won a featherweight world title in his third pro fight and made his second defense on Saturday's Mayweather-Pacquiao undercard. He is a special talent with pound-for-pound potential. You have to figure he will eventually move up in weight and someday be a lightweight. Given that he recently signed a five-year contract extension with Top Rank, he and Verdejo have the same promoter, and they are both fighting on HBO. That means it would be a relatively easy fight to make down the road.

"That's going to be a huge fight, maybe in three years," Arum said.