A 22-year-old Melbourne man shot dead in a garage in front of his friends has been remembered as a “respectable, special boy”.

The victim, known as Moe, had finished playing video games when he was fatally shot in the chest near the back laneway of a Keysborough home last night.

One of his friends, aged 23, suffered a gunshot wound to the arm while another 22-year-old friend was hit in the leg.

A local resident told 9NEWS he arrived at the scene before police.

A neighbour said the young man had been playing a FIFA video game before he was fatally shot. (9NEWS)

“When we walked past them we could see what was actually going on, I could hear a lot of screaming like ‘please stop, no no’," he said.

A neighbour, who didn't want to be named, said she barricaded herself and her young daughter in a walk-in wardrobe as she called police.

"My daughter was upstairs sleeping. The gunshots were so loud and sharp I can still hear it," the woman said.

Friends and family of Moe visited the home today to offer their sympathy.

“He was a special boy, respectable, known as a good guy and his family is a very nice family,” close friend Naile told 9NEWS.

She said friends of Moe were struggling to cope with the ordeal.

“They’re all devastated.”

Detectives are combing the crime scene for evidence following the triple shooting. (9NEWS)

Police are yet to establish a motive for the attack and said the victims were not known to authorities.

"The two survivors are lucky, and we will be putting a lot of extra police in here over the next few weeks," Inspector Mark Langhorn said earlier today.

Investigators are looking for a dark-coloured 4WD and a "shiny car" seen speeding away from the scene.

The victim’s two friends remain in a stable condition in The Alfred hospital.