Sens. Sens. Elizabeth Warren Elizabeth WarrenHillicon Valley: Subpoenas for Facebook, Google and Twitter on the cards | Wray rebuffs mail-in voting conspiracies | Reps. raise mass surveillance concerns On The Money: Anxious Democrats push for vote on COVID-19 aid | Pelosi, Mnuchin ready to restart talks | Weekly jobless claims increase | Senate treads close to shutdown deadline Democratic senators ask inspector general to investigate IRS use of location tracking service MORE (D-Mass.) and Bernie Sanders Bernie SandersThe Hill's Campaign Report: Trump faces backlash after not committing to peaceful transition of power Bernie Sanders: 'This is an election between Donald Trump and democracy' The Hill's 12:30 Report: Trump stokes fears over November election outcome MORE (I-Vt.) beat back against an onslaught of attacks from the moderate candidates at a testy debate on Tuesday night that exposed deep divisions between the centrists and the liberals seeking to challenge President Trump Donald John TrumpSteele Dossier sub-source was subject of FBI counterintelligence probe Pelosi slams Trump executive order on pre-existing conditions: It 'isn't worth the paper it's signed on' Trump 'no longer angry' at Romney because of Supreme Court stance MORE.

The centrist Democrats wasted no time going after two of the party’s leading liberals, warning that proposals from Sanders and Warren would lead to electoral ruin if Democrats embrace them against Trump in the general election next year.

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Former Colorado Gov. John Hickenlooper John HickenlooperThe Hill's Morning Report - Sponsored by Facebook - Trump previews SCOTUS nominee as 'totally brilliant' Cook Political Report shifts Colorado Senate race toward Democrat Willie Nelson playing at virtual fundraiser for Hickenlooper MORE argued that Democrats flipped 40 GOP seats in the House in 2018 and “not one of those candidates supported the policies of our front-runners at center stage.”

Montana Gov. Steve Bullock Steve BullockMcConnell locks down key GOP votes in Supreme Court fight Senate Democrats demand White House fire controversial head of public lands agency Pence seeks to boost Daines in critical Montana Senate race MORE, making his first appearance at the Democratic debate, said that the liberal candidates are “trying to outdo each other with wish-list economics” that wouldn't fly in his red state.

And former Rep. John Delaney John DelaneyCoronavirus Report: The Hill's Steve Clemons interviews Rep. Rodney Davis Eurasia Group founder Ian Bremmer says Trump right on China but wrong on WHO; CDC issues new guidance for large gatherings The Hill's Coronavirus Report: Kansas City Mayor Quinton Lucas says country needs to rethink what 'policing' means; US cases surpass 2 million with no end to pandemic in sight MORE (D-Md.) said that if Sanders or Warren are nominated, Democrats will lose in a landslide similar to those suffered by George McGovern or Michael Dukakis.

“If we go down the road Sens. Sanders and Warren want to take with bad policies like 'Medicare for All' and other impossible promises, it will turn off independent voters and get Trump reelected,” Delaney said.

The warnings from the moderates provoked a fierce debate about Medicare for All, with Sanders and Warren fighting back and accusing the centrists of mischaracterizing their plans.

“Let’s be clear about this,” Warren said. “We are the Democrats and we are not about trying to take health care away from anyone...and we should stop using Republican talking points.”

Sanders even fired back at moderator Jake Tapper Jacob (Jake) Paul TapperThe media's misleading use of COVID-19 data Julia Louis-Dreyfus: 'We can't spend much time grieving' Ginsburg Pence aide dismisses concerns rushed vote on Trump nominee will hurt vulnerable senators MORE, who had gone down the line of candidates asking if they support raising taxes on middle class workers to pay for Medicare for All.

“What I’m talking about it and others up here are talking about is no deductibles and no copayments, and Jake, your question is a Republican talking point,” Sanders said. “At the end of the day, and by the way, the health care industry will be advertising tonight on this program.”

The battle over Medicare for All dominated the entire first half hour of the debate.

No issue has split the Democratic Party more in the 2020 primary than health care, with centrists warning that Medicare for All is intrusive government intervention and a general election loser.

Some Democrats have warned that embracing Medicare for all will lead Republicans to characterize them as socialists.

“It’s time to stop worrying about what the Republicans say,” South Bend, Ind., Mayor Pete Buttigieg Pete ButtigiegBillionaire who donated to Trump in 2016 donates to Biden The Hill's Morning Report - Sponsored by Facebook - GOP closes ranks to fill SCOTUS vacancy by November Buttigieg stands in as Pence for Harris's debate practice MORE said. “If we embrace a far left agenda, they’ll say we’re crazy socialists. If we embrace a conservative agenda, they’ll say the same thing.”

But on Tuesday night, the moderates came out swinging at Medicare for all with grave warnings about the electoral consequences. Montana Gov. Steve Bullock was perplexed that Democrats would consider Medicare for All, rather than building on ObamaCare.

“This is an example of wish list economics,” Bullock said. “It used to be Republicans who wanted to repeal and replace ObamaCare, now it’s Democrats.”

“We have all our union friends here tonight…this plan offered by Sanders and Warren will tell those union workers…they’ll lose their health care because Washington tells them they have a better plan,” added Rep. Tim Ryan Timothy (Tim) RyanNow's the time to make 'Social Emotional Learning' a national priority Mourners gather outside Supreme Court after passing of Ruth Bader Ginsburg Lincoln Project hits Trump for criticizing Goodyear, 'an American company' MORE (Ohio).

Sanders fired back when Ryan told him he couldn’t be certain that Medicare for All will lower costs for elderly people.

“You don’t know that,” Ryan said.

“I do know that,” Sanders responded. “I wrote the damn bill.”

The centrist versus progressive debate also spilled into immigration, with Warren receiving fire for advocating for decriminalizing illegal border crossings and providing health care to those in the country illegally.

"We need to fix the crisis at the border and a big part of how we do that is we do not play into Donald Trump’s hands,” Warren said.

Bullock fired back: “But you are playing into Donald Trump’s hands…a sane immigration system needs a sane leader and we can do that without decriminalizing or providing health care for everyone. It’s not just me saying that, it’s Obama’s homeland security secretary.”

And Sanders was grilled for proposing health care for those in the country illegally.

“I happen to believe that when I talk about health care it’s a human right that applies to all people in this country,” he said.

-- Updated at 9:24 p.m.