A Queensland couple and an Adelaide man are hoping to remain anonymous after each picked up $53 million in last night's biggest division one Oz Lotto prize.

It was beginner's luck for the Gold Coast couple who had never bought an Oz Lotto ticket before and went to work today despite their new-found wealth.

Mal Neilson, the owner of the Mermaid Beach newsagency where the winning ticket was bought, says he feels like he won first division as well.

"I'm just lucky to be here I think. It's all positive and it's all good fun. It has its critics [who say] 'but it's gambling and it's punting' and I tell people 'if they can't afford it don't do it'," he said.

The disbelieving South Australian punter had been a regular player for 20 years.

The man in his 40s from Adelaide's western suburbs says he felt numb as he watched his numbers drop on the televised draw.

Rebecca Payne from South Australian Lotteries broke the news to him.

"He said, 'I can't quite believe this' and he was in quite a state of shock as it was," Ms Payne said.

"That's when he said to me, 'so how much have I won - $2 million, $3 million?'

"And I said to him, 'are you sitting down?' And that's when I said, 'you've actually won slightly more than that - you've won $53 million'.

"And he just went, 'Oh you just blew my mind'."

A massive 10 million entries went into the draw for the chance to win the record $106 million.

Golden Casket Lottery says both winners want to help out family and donate money to some charities.

The winning numbers were 12, 3, 38, 21, 23, 29 and 40, with 43 and 22 as the supplementary numbers.

- ABC/AAP