Sen. Elizabeth Warren Elizabeth WarrenHillicon Valley: Subpoenas for Facebook, Google and Twitter on the cards | Wray rebuffs mail-in voting conspiracies | Reps. raise mass surveillance concerns On The Money: Anxious Democrats push for vote on COVID-19 aid | Pelosi, Mnuchin ready to restart talks | Weekly jobless claims increase | Senate treads close to shutdown deadline Democratic senators ask inspector general to investigate IRS use of location tracking service MORE (D-Mass.) on Tuesday called Labor Secretary Alexander Acosta Alex Alexander AcostaFederal litigator files complaint alleging Labor secretary abused his authority Appeals court to review legality of Epstein plea deal Appeals court finds prosecutors' secret plea agreement with Epstein didn't break law MORE "ethically compromised and unfit to serve" after a non-prosecution agreement for Jeffrey Epstein that he oversaw reentered the news.

Under the agreement, Epstein, who has been accused of sexual assault by more than 30 girls, was sentenced to serve just 13 months in jail, and he and his co-conspirators were given further immunity. Acosta was serving as a U.S. attorney in Miami at the time.

Epstein was rearrested Saturday and charged with sex trafficking. He pleaded not guilty on Monday.

"I opposed Secretary Acosta's nomination, and voted against his confirmation," Warren tweeted. "The last few days have only highlighted how ethically compromised and unfit to serve he is. Acosta must resign—now."

I opposed Secretary Acosta's nomination, and voted against his confirmation. The last few days have only highlighted how ethically compromised and unfit to serve he is. Acosta must resign—now. https://t.co/0XPrLO4N9K — Elizabeth Warren (@ewarren) July 9, 2019

Several other 2020 presidential candidates also called on Acosta to step down. But Acosta defended the decade-old deal on Tuesday.

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"With the evidence available more than a decade ago, federal prosecutors insisted that Epstein go to jail, register as a sex offender and put the world on notice that he was a sexual predator,” he tweeted.