New York State Sen. Michael Gianaris on Friday defended his opposition to Amazon's now-scuttled plan for what would have been a new headquarters in the Queens section of New York City.

"Amazon needs to get ahold of what they mean to communities, and act responsibility," Gianaris said in an interview with CNBC's "Squawk Box." "When they come in and take over a community like that, the community dies."

The New York Post, known for its edgy cover headlines, called Gianaris "the man who killed the Amazon deal."

Gianaris, whose district includes the Long Island City neighborhood in Queens where Amazon had agreed to build, claims Seattle businesses have not really benefited from having the e-commerce giant based there.

"In Seattle, the local restaurants are dying," he argued. "It's all insular to the campus. They go home at 5 o'clock. No one is having dinner in those restaurants."

"If you're going to come to a community, and you're going to turn Long Island City into what's happened in those towns in Seattle that I mentioned, you got to come correct and say, 'I want to help this community thrive,'" he added.

In response, a spokesperson for Amazon said Gianaris' comments on Seattle were "incorrect" and pointed CNBC to a blog post on the company's impact on the city. The Amazon post said the company has paid more than $25 billion in wages to its local workforce and invested $4 billion into its Seattle campus.

The city of Seattle did not immediately respond to CNBC's request for comment on Gianaris' interview.