A siege in the Tasmanian city of Launceston has ended with police arresting a 24-year-old man and a woman, 40, after 33 shots were fired at police.

Police had brought in negotiators, a heavily armoured Bearcat truck and evacuated residents from the street during the 18 hour stand-off which began on Friday afternoon.

The drama began around 4.30pm on Friday when police went to the New World Avenue home in the northwestern Launceston suburb of Trevallyn to conduct inquiries.

The man and woman barricaded themselves inside the house and the man began firing at officers. No one was injured.

#TrevallynSeige officers escorting a second person from the property to a police van. pic.twitter.com/5ZK69Msboa — Laura Beavis (@laurajbeavis) December 7, 2018

Dramatic end to the Launceston siege - loud bangs as armed officers storm the Trevallyn residence. Two in custody. More to come @tasnightlynews pic.twitter.com/7JskjYO9ew — Tom Johnson (@tomjohnson1991) December 7, 2018

“We have negotiators who are negotiating with the persons in the house to peacefully resolve it,” Detective Inspector Philippa Burk told The Mercury on Friday night. “At this point in time we are not treating it as a hostage situation.

“My best advice to both of them is to surrender, put the gun down ... and hand yourself in to police.

“Until the situation at Trevallyn is safely resolved, people living in the nearby area may hear a range of loud noises over the next few hours and potentially throughout the night,” Commander Brett Smith said in a statement.

Up to 34 police officers from a range of specialty units were deployed.