Twenty-nine years ago, Rizzoli Bookstore, whose Old World charm, hand-wrought chandeliers and big storefront windows make it a favorite of noted authors, book lovers and tourists, fled Fifth Avenue two steps ahead of the wrecking ball.

It may now have to take flight again.

The owners of the building at 31 West 57th Street near Fifth Avenue that houses Rizzoli — the LeFrak real estate family and Vornado Realty Trust — recently gave the bookstore the bad news: They plan to demolish the six-story, 109-year-old building, as well as two small, adjoining buildings.

The owners declined to describe their plans on 57th Street, where a string of extremely tall and slender ultraluxury towers are under construction.

“I can’t comment on those buildings,” Harrison T. LeFrak said. “If you have any questions, speak to my partner.”