Planned Parenthood is targeting Republican senators in a seven-figure ad campaign over the Trump administration's changes to a federally funded birth control program.

The campaign, which will include ads on television, radio and digital platforms, as well as mailers, will target three Republican incumbents who Democrats hope to defeat in 2020: Sens. Cory Gardner Cory Scott GardnerBreaking the Chinese space addiction Trump dumbfounds GOP with latest unforced error Billionaire who donated to Trump in 2016 donates to Biden MORE (R-Colo.), Martha McSally Martha Elizabeth McSallySenate GOP set to vote on Trump's Supreme Court pick before election Netflix distances from author's comments about Muslim Uyghurs but defends project On The Trail: Making sense of this week's polling tsunami MORE (R-Ariz.) and Thom Tillis Thomas (Thom) Roland TillisNetflix distances from author's comments about Muslim Uyghurs but defends project Overnight Energy: Trump officials finalize plan to open up protected areas of Tongass to logging | Feds say offshore testing for oil can proceed despite drilling moratorium | Dems question EPA's postponement of inequality training On The Trail: Making sense of this week's polling tsunami MORE (R-N.C.).

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Planned Parenthood and other groups left the Title X family planning program earlier this year arguing they could not ethically follow the Trump administration's new rules blocking providers from referring people for abortions.

Planned Parenthood predicts outrage over the change will lead to a backlash against Trump and Republicans in 2020.

An ad airing in Colorado argues that Gardner doesn't "care about women's health."

Gardner has not made any public comments about the administration's decision. But he and other Republicans, including Tillis and McSally, have previously voted to block federal funds from going to Planned Parenthood.

Planned Parenthood has pushed Congress to block the administration from enforcing the changes in an upcoming spending bill, but that is unlikely while Republicans control the Senate.

Republicans canceled a vote on a spending bill in September after Democrats said they would offer an amendment that would block the administration's changes.

"Congress has the power to take action, and the American people want them to stop putting politics over their health and protect access to affordable health care," said Sam Lau, director of federal advocacy media for Planned Parenthood Action Fund.

The changes also prohibit abortion providers from participating in the program, although Title X funds aren't used for abortions.

The Hill has reached out to the Tillis, McSally and Gardner campaigns for comment.