A conservative radio host has blasted Arizona Senator John McCain, calling him "a backstabber, O.J.-style."

Bill Cunningham made the comment Sunday on ABC News' "This Week" mentioning Trump's recent rally-style speech in Youngstown, Ohio, Cunningham, "I don't think any president after six or seven months could travel the way the Trumpster has traveled with the outpouring of love and affection despite the fact that a few days ago, the backstabber, O.J.-style, who is Senator John McCain, that began his public life as a hero, and is ending up giving a thumbs down and a middle finger to the middle class by not repealing Obamacare."

The radio host was referring to the thumbs-down "no" vote McCain gave on the Senate floor early Friday morning which ended up being a deciding factor in the GOP's latest defeat to overhaul the current health care law.

Click through McCain voting no on Obamacare 'skinny' repeal:

6 PHOTOS McCain votes no on Obamacare 'skinny' repeal See Gallery McCain votes no on Obamacare 'skinny' repeal WASHINGTON, DC - JULY 27: Sen. John McCain (R-AZ) holds a news conference with fellow GOP senators to say they would not support a 'Skinny Repeal' of health care at the U.S. Capitol July 27, 2017 in Washington, DC. The Republican senators said they would not support any legislation to repeal and replace Obamacare unless it was guaranteed to go to conference with the House of Representatives. (Photo by Chip Somodevilla/Getty Images) WASHINGTON, DC - JULY 27: (L-R) Sen. Lindsey Graham (R-SC), Sen. John McCain (R-AZ) and Sen. Ron Johnson (R-WI) hold a news conference to say they would not support a 'Skinny Repeal' of health care at the U.S. Capitol July 27, 2017 in Washington, DC. The Republican senators said they would not support any legislation to repeal and replace Obamacare unless it was guaranteed to go to conference with the House of Representatives. (Photo by Chip Somodevilla/Getty Images) Senator John McCain (R-AZ) speaks with reporters after voting against the "skinny repeal" health care bill on Capitol Hill in Washington, U.S., July 28, 2017. REUTERS/Aaron P. Bernstein TPX IMAGES OF THE DAY WASHINGTON, DC - JULY 27: Sen John McCain (R-AZ) leaves the Senate Chamber after a vote on a stripped-down, or 'Skinny Repeal,' version of Obamacare reform on July 28, 2017 in Washington, DC. McCain was one of three Republican Senators to vote against the measure. (Photo by Zach Gibson/Getty Images) Senator John McCain (R-AZ) speaks during a press conference about his resistance to the so-called "Skinny Repeal" of the Affordable Care Act on Capitol Hill in Washington, U.S., July 27, 2017. REUTERS/Aaron P. Bernstein WASHINGTON, DC - JULY 28: Sen. John McCain (R-AZ) leaves the the Senate chamber at the U.S. Capitol after voting on the GOP 'Skinny Repeal' health care bill on July 28, 2017 in Washington, DC. Three Senate Republicans voted no to block a stripped-down, or 'Skinny Repeal,' version of Obamacare reform. (Photo by Justin Sullivan/Getty Images) Up Next See Gallery Discover More Like This HIDE CAPTION SHOW CAPTION of SEE ALL BACK TO SLIDE

The two other Republican senators who voted against the so-called "skinny repeal" bill, Maine's Susan Collins and Alaska's Lisa Murkowski, had consistently spoken out against their party's efforts so far on the bill.

After his surprising vote, McCain, who was recently diagnosed with brain cancer, issued a statement saying, "I've stated time and time again that one of the major failures of Obamacare was that it was rammed through Congress by Democrats on a strict-party line basis without a single Republican vote. We should not make the mistakes of the past that has led to Obamacare's collapse, including in my home state of Arizona where premiums are skyrocketing and health care providers are fleeing the marketplace."

The fate of the nation's health care law is now uncertain, but Trump himself has weighed in with various thoughts; after the vote failed, the president tweeted, "3 Republicans and 48 Democrats let the American people down. As I said from the beginning, let ObamaCare implode, then deal. Watch!"

He then posted a message on Saturday, writing, "If a new HealthCare Bill is not approved quickly, BAILOUTS for Insurance Companies and BAILOUTS for Members of Congress will end very soon!"

Trump added soon after, "Unless the Republican Senators are total quitters, Repeal & Replace is not dead! Demand another vote before voting on any other bill!"

He continued Sunday morning, "Don't give up Republican Senators, the World is watching: Repeal & Replace...and go to 51 votes (nuke option), get Cross State Lines & more."