First, top business leaders abandoned President Trump. Now, major organizations are canceling plans to hold events at the president's resort in Florida.

The Cleveland Clinic, the American Cancer Society and American Friends of Magen David Adom have all axed plans for galas at Trump's private Mar-a-Lago club.

It will be the first time in eight years that the Cleveland Clinic has not held its fundraiser at the resort in South Florida, which Trump has dubbed the Winter White House.

The cancellations follow the spectacular implosion of Trump's business councils this week over the president's comments that drew a moral equivalence between white supremacists and left-wing protesters.

The collapse of the councils was an extraordinary rebuke to a president who prides himself on being business-friendly. High-profile CEOs like JPMorgan Chase's (JPM) Jamie Dimon have publicly slammed Trump's reaction to the violence that broke out at a white supremacist rally in Charlottesville, Virginia, on Saturday.

Now, Trump's words appear to be hurting his own business.

Related: Stunning rebuke for the CEO president

"We thank the staff of Mar-a-Lago for their service over the years," the Cleveland Clinic said in a statement. It did not give a reason for its cancellation. The announcement was reported earlier Thursday by the Cleveland Plain Dealer.

Toby Cosgrove, the hospital group's CEO, was among the executives on one of Trump's business councils.

A few hours after the Cleveland Clinic's announcement, the American Cancer Society followed suit.

The nonprofit said in a statement that it had planned to host its 2018 gala at Mar-a-Lago "based on a variety of factors, including costs and venue requirements." But the organization said "it has become increasingly clear" that hosting its fundraiser on Trump-owned property presents a "challenge" to its values.

The American Cancer Society -- which has hosted the annual event at Mar-a-Lago for at least the past decade -- has not yet selected another venue. The decision was reported earlier by the Palm Beach Post.

Mar-a-Lago declined to comment. The Trump Organization did not immediately respond to a message.

Related: America's top CEOs always had an awkward relationship with Trump

The health organization last hosted its gala in Trump's Palm Beach club in February of this year.

That event coincided with a visit from Trump, who was in Florida the same weekend to meet with Japanese Prime Minister Shinzo Abe.

It's not clear whether Trump attended any portion of the American Cancer Society's event, but he is known to pop in on fundraisers. In fact, Trump served as a co-chair for the American Cancer Society's annual event in 2014, the organization said.

The American Friends of Magen David Adom, a group that supports Israel's national ambulance, blood-services and disaster-relief organization, confirmed that it, too, has decided to move its annual gala to another location.

"After considerable deliberation, AFMDA — an apolitical and humanitarian aid organization — will not hold its 2018 Palm Beach Celebration of Life Gala at Mar-a-Lago," spokesperson Erik Levis said in a statement.

The event was scheduled to take place at Mar-a-Lago on Feb. 25, 2018.

Related: What happened behind the scenes as Trump's business councils fell apart

On Thursday, CNNMoney reached out to all the organizations that have announced plans to hold events at Mar-a-Lago in the coming months.

Only one other organization, Kravis Center for the Performing Arts, responded to CNNMoney's inquiries.

That group confirmed it will host a wine auction at the club on Feb. 1.

- An earlier version of this story misidentified the location of the American Friends of Magen David Adom.