There are public health leaders on both sides of the debate who agree on reasonable regulations. The FDA should limit the amount of liquid nicotine in any container sold to consumers, stop sales on the Internet, and require childproof packaging. It should ban marketing and sales to minors, including sponsorship, free samples, use of cartoon characters and use of labels and flavoring that appeal to children. It will be good news if it is shown that e-cigarettes saves lives by reducing the number of people who smoke ordinary cigarettes and die of tobacco-related disease. But there is scant evidence of that so far. And they must be safely manufactured, responsibly marketed, and appropriately regulated regardless.