Tom Brokaw, the longtime NBC News anchor, issued a pointed rebuke on Friday to a former colleague who has accused him of groping and harassing her during the 1990s, describing himself as “angry, hurt and unmoored from what I thought would be the final passage of my life and career.”

In a lengthy email message — written, by his account, at 4 a.m. — Mr. Brokaw angrily rejected the claims of the woman, Linda Vester, a former correspondent at NBC News and Fox News. “I was ambushed and then perp walked across the pages of The Washington Post and Variety,” Mr. Brokaw wrote, referring to the news organizations that on Thursday night published Ms. Vester’s account.

He added, of his accuser, “Hard to believe it wasn’t much more Look At Me than Me:Too.”

In the news reports, Ms. Vester described Mr. Brokaw tickling her in a conference room, asking her to drinks and, on two occasions in New York and London, inviting himself to her hotel room. There, she said, he grabbed her and tried to force her to kiss him.

She said that the encounters had left her feeling humiliated and isolated, and that she had been scared to report Mr. Brokaw’s behavior, fearful it could wreck her career. At the time, Ms. Vester was among the youngest correspondents at NBC News, and Mr. Brokaw, who has been married since 1962, was the most powerful figure in the news division.