Two young men have gone missing on a Canadian highway just days after an Australian backpacker and his American lover were shot dead in the same region.

Canadian police have urgently requested the public's help in finding teenager Kam McLeod, 19, and Bryer Schmegelsky, 18.

The truck the young Canadians were driving was found on fire on Highway 37 near Dease Lake, in British Columbia, last Friday.

The body of a third, unknown man was found nearby.

The disappearance of the two men comes a week after New South Wales man Lucas Fowler, 24, and Chynna Deese, 23, from North Carolina, were shot dead on the province's remote Alaska Highway.

Local police have repeatedly dismissed fears of a serial killer.

However, in a statement today, the Royal Canadian Mounted Police acknowledged 'growing community concerns about the ongoing homicide investigations in northern British Columbia'.

MISSING: Kam McLeod and Bryer Schmegelsky have disappeared driving around the same region of Canada as Australian man Lucas Fowler and American woman Chynna Deese

The red and grey Dodge 'pickup truck' the pair were travelling in when they disappeared

Shot dead: Lucas Fowler, the 24-year-old son of a senior New South Wales police officer, and his girlfriend Chynna Deese, from Charlotte, North Carolina, were found dead on the Alaska Highway last Monday

Fowler and Deese's beat-up Chevrolet minivan is pictured with the back window smashed in and covered with a plastic patch

Investigators looking into the incidents are sharing information, the police spokeswoman said.

Officers pointed out Kam and Bryer's car was found 470 kilometres from Lucas and Chynna's bodies and the incidents were five days' apart.

Of the missing two boys, police spokeswoman Dawn Roberts said: 'Kam and Bryer have periodically connected with family and friends over the past week and it is possible that they are now in area without cell coverage.

'However, we have found their vehicle and have not been able to locate either of them at this time.

'We are asking for Kam or Bryer to connect with police right away and let us know you are okay.

Tourists flood British Columbia's Rocky Mountains hot-spots at this time of year like Banff and Jasper for hiking and hot springs adventures.

Who exactly killed Fowler and Deese remains a mystery, with one witness claiming to have seen the couple having a 'heated exchange' with a bearded man last Sunday.

The couple's beat-up Chevrolet minivan was seized by police and was pictured for the first time earlier today with a blown out back window.

Witnesses to Fowler and Deese's final moments have came forward to tell of their final encounters with the tragic couple.

Good Samaritans Sandra Broughton and her husband Curtis claimed to have a fateful encounter with the young lovers last Sunday.

Good Samaritans Sandra and Curtis Broughton offered to help the broken down couple

They were heading home along Alaska Highway after visiting Liard Hot Springs on Sunday at 3.20pm when they saw Mr Fowler and Ms Deese's van broken down on the side of the road.

Mr Broughton, a mechanic, presumed they needed help and pulled over. He said the couple were relaxing on fold-out chairs on the side of the road and were 'happy and smiling' despite the circumstances.

'They were having lunch or a bit of a meal when we pulled up.'

Mr Broughton soon realised the Australian had it all under control.

'He seemed like he had everything diagnosed properly,' he said.

'The vehicle was flooded out and they were going to try and get it going again until they could get the parts they needed.'

The Broughtons got back in their car and drove home.

Days later, they heard what had happened to them on the news.

Ms Broughton told reporters: 'We were like angels offering to help, being the good in the world but unfortunately they also met the worst and in humanity.'

Another eyewitness has also come forward claiming have seen the young travellers having a 'heated exchange with a bearded man'.

Road worker Alanda Hull said the couple were standing beside their van and seemed bothered by the man, who she saw in the middle of the road.

'If you just get a bad feeling, and that's what I had, you just don't stop,' Ms Hull told the Nine Network.

The disappearance of the two men comes a week after New South Wales man Lucas Fowler, 24, and Chynna Deese, 23, from North Carolina, were shot dead on the province's remote Alaska Highway

This Chevrolet mini-van was found at the scene (pictured)

Fowler, the son of New South Wales police inspector Stephen Fowler, and Deese, from met at a hostel in Croatia two years ago.

They fell in love and were travelling across Canada as part of the latest chapter in their globetrotting adventure.

Since 2017, Fowler, from Sydney's north, had travelled to locations as diverse Myanmar, Japan, Hungary, Spain, South America and Canada.

Before taking off overseas, he played football with the Asquith Soccer Club and lived in Ku-ring-gai.

One of his friends this week paid tribute to the 'kindest, funniest, sweetest, most carefree and happy human I have ever come across in my life.'

'No matter what was going on you would just walk in with a beer in one hand, smile and say 'she'll be right'.'

His family has flown to Canada to bring his body home. Two NSW homicide detectives are also joining the investigation.

World explorers: Chynna Deese (left) and Lucas Fowler (right) at the Grand Canyon and in Myanmar respectively. The couple met at a hostel in Croatia two years ago

Meanwhile, the Deeses have told media they fear the killer may strike again.

'I don't think it's a serial killer,' Ms Deese's father, Dwayne, told the Charlotte Observer.

'I think of someone who has been convicted of violent crimes before, someone on drugs.

'That fits the profile better.

'What worries us is that person is still on the loose and they have a head start.

'This is going to happen again.

'There needs to be some kind of a warning system in place for tourists.'