The changes from year to year are just fascinating. I've written before about the disappearance and reappearance of Jupiter's South Equatorial Belt, which is probably the most obvious of the time-varying features visible here. But there is so much more to see. Look at the region to the left of the Great Red Spot. Is it turbulent like when Cassini passed by, or smooth like when New Horizons passed by? Look at the color and banding within the Red Spot. Look, too, at the color of the Little Red Spot (also known as Oval BA). In 2009 and 2012 you can see that there's actually another Red Spot in Jupiter's northern hemisphere, a bit smaller than Oval BA. Check a red belt in any location in one year and see how different it appears in other years. The variety in the appearance of the northern hemisphere from year to year is fascinating.

For a bit more historical perspective, compare the views above to these six global views from the Pioneers, Voyagers, Cassini, and New Horizons: