SAN FRANCISCO -- Good note from the San Francisco 49ers this morning: Aldon Smith needs 1.5 sacks against Buffalo to break Reggie White's sack-era record for fewest games to reach 20 career sacks.

White needed 22 games. Smith has 18.5 sacks in his first 20 regular-season games.

Smith, who led the 49ers with 14 sacks as a rookie in 2011, had one sack wiped out by penalty in Week 4. He has 4.5 sacks through four games this season, putting him on pace for 18 sacks over a 16-game season.

Bills quarterback Ryan Fitzpatrick has taken only four sacks in 136 drop backs this season.

Additional Bills-49ers notes, from ESPN Stats & Information: