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A celebrity cosmetic dermatologist has been found dead after being left 'devastated' by comparisons to a character on a hit US comedy show.

Fredric Brandt, 65, died at his Miami home Sunday - with his publicist saying he had been suffering from an 'illness'.

Dr Barandt had become well-known after providing skin treatments from superstars such as Madonna and Stephanie Seymour.

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But before his death he was said to have been left 'devastated' by comparisons to comedy character Dr Franff in Tina Fey's Netflix show Unbreakable Kimmy Schmidt.

Dr Franff - played by Martin Short - appears in one episode of the show's first series and shares a striking resemblance to Dr Brandt with his smooth skin, platinum blonde hair and enthusiasm for cosmetic surgery.

(Image: Getty Images)

The oddball character spawned unusual one-liners including saying, "It's like asking me which one of my children's placentas was the most delicious" when asked which cosmetic foot procedure he would recommend.

Dr Brandt's publicist Jacquie Tractenberg said the doctor was an 'amazing man'.

She told the New York Post : He was suffering from an illness. Everyone who knows him is devastated.

(Image: Netflix)

"I worked with him for over 20 years and he was an amazing man, not only what he a brilliant doctor, but he was the kindest human being."

She declined to comment further on the circumstances surrounding his death or reports Dr Brandt had been suffering from depression.