Police have arrested five teenagers in relation to the sexual assault of a homeless girl in a Melbourne lane.

The 16-year-old girl was searching for temporary accommodation in Brunswick on February 23 when she was approached by a group of men.

They allegedly dragged her off Sydney Road into a lane where she was sexually assaulted, police said.

Victoria Police spokeswoman Kelly Yates said officers arrested a 18-year-old Point Cook man, two 18-year-old men from Hoppers Crossing, and two 17-year-olds, who could not be identified because they were under 18.

No charges have been laid.

‘‘We expect to lay charges in coming weeks,’’ Ms Yates said.