BOSTON -- Jake Arrieta certainly picked two of baseball's most historic places to put on memorable performances.

Arrieta held the Red Sox hitless until Stephen Drew singled with two outs in the eighth inning, and the Chicago Cubs beat the Boston Red Sox 2-0 on Monday night in the opener of only the second series between the teams at Fenway Park since 1918.

Six days after losing a perfect game on a leadoff single in the seventh inning of his previous start at Wrigley Field against Cincinnati, Arrieta took his no-hit bid a little deeper at Fenway. He allowed only Mike Napoli's fifth-inning walk before Drew lined a sharp single to right.

"It's special to do it in this ballpark," Arrieta said. "It was special to do it last week in Wrigley and to do it here in these two parks is pretty special."

Starting the season on the disabled list with shoulder tightness, the 28-year old right-hander was pushing his pitch limit before Drew lined a 2-2 pitch.

Arrieta (5-1) was lifted by Cubs manager Rick Renteria immediately following the hit that came on his career-high 120th pitch.

The 28-year-old Arrieta was given a loud ovation before he even got to the foul line, tipping his cap to the Boston crowd. He tipped it again after crossing the line.

"Something like that in Fenway is pretty rare for an opposing team, so yeah I got some goosebumps there," he said. "That's why you play this game, for moments like that. I was very thankful to be a part of something like that."

Arrieta fanned 10 in just his 11th start of the season.

"Awesome. That was some kind of awesome," Renteria said of the ovation. "We were standing out there at the mound. That was some show of respect."

Drew's hit ensured the Red Sox wouldn't be no-hit for the first time since Cubs pitching coach Chris Bosio pitched a no-no against Boston in 1993 for Seattle.

Arrieta's performance helped jog Bosio's memory of his special night.

"Everything," Bosio said when asked what he recalled from his no-hitter. "We had just come off a long road trip from Detroit and Toronto and I was real sick before the game. I had cut my warmup in half. I pretty much remember everything from the game. Every play, every at-bat right up until the last out."