Metformin has been shown to restore cells in mice and rat brains to a healthier state

Scientists have discovered that a drug already used by the NHS can make brain cells younger, a breakthrough which could transform treatment for patients with multiple sclerosis.

The diabetes drug metformin has been shown to restore cells in mice and rat brains to a healthier, younger state. Fasting on alternate days has a similar result. This could help MS patients to better reproduce myelin, which protects the nerves but is attacked by the immune system in MS, exposing nerves and making it difficult for the brain to send messages around the body.

The discovery has been announced as the MS Society begins a fundraising appeal for £100 million over a decade to accelerate research to stop disability caused by the condition.

Robin Franklin, director of