Bulging at beach in 1949, 197-pound Dorothy [Bradley] self-consciously leaves locker room for swim. She covered up embarrassment by being jolly and gregarious.

Dorothy Bradley, photographed for LIFE magazine article on obesity, 1949.

Hungry at drugstore after a day's work earning money for nursing school, Dorothy envies slim girl's milkshake, orders lemonade without sugar for herself.

In March 1954,magazine ran an article titled “The Plague of Overweight” which in part followed the weight loss challenges faced by 205-pound Dorothy Bradley, 31, originally from Tennessee, began with a sentence that would not have been out of place in a 2013 news report: “the most serious health problem in the U.S. today is obesity.”The article chronicled Dorothy’s efforts to lose weight; her desire to work in medicine; her successes (losing 60 pounds) and her backsliding (gaining it all back, and then some); and ultimately, something of a happy ending, as she lost and, as of the article’s publication, had kept off close to 70 pounds and earned a job as head nurse at a hospital in Kentucky.Here are some rare pictures from, many of which never ran in the magazine, made by photographer Martha Holmes to illustrate the March 1954 article.