President Trump Donald John TrumpBiden leads Trump by 36 points nationally among Latinos: poll Trump dismisses climate change role in fires, says Newsom needs to manage forest better Jimmy Kimmel hits Trump for rallies while hosting Emmy Awards MORE fired Secretary of State Rex Tillerson Rex Wayne TillersonGary Cohn: 'I haven't made up my mind' on vote for president in November Kushner says 'Alice in Wonderland' describes Trump presidency: Woodward book Conspicuous by their absence from the Republican Convention MORE on Tuesday in what many at the White House believe could be the first of a new round of high-profile changes within the administration.

White House officials were not sorry to see Tillerson go, viewing him as an ineffective leader who was rarely on the same page as Trump.

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In a sign of the bitterness between the White House and Tillerson’s circle, officials joked about fighting for the right to fire one of Tillerson’s top spokesmen, Steven Goldstein, who had issued a statement that differed from the White House account of the secretary’s exit.

Tillerson did not thank the president in his farewell speech and barely mentioned him, underscoring the bad blood.

In his own remarks, Trump said he and Tillerson were never on the same “wavelength” while heaping praise on CIA Director Mike Pompeo Michael (Mike) Richard PompeoUS reimposes UN sanctions on Iran amid increasing tensions Sunday shows preview: Justice Ginsburg dies, sparking partisan battle over vacancy before election Trump steps up Iran fight in final election stretch MORE, whom he nominated as the next secretary of State.

Trump signaled that more changes could be on the way.

“I'm really at a point where we're getting very close to having the Cabinet and other things that I want,” he said.

Veterans Affairs Secretary David Shulkin David Jonathon ShulkinVA inspector general says former top official steered M contract to friend Schumer demands answers in use of unproven coronavirus drug on veterans Former Trump VA secretary says staffer found plans to replace him in department copier MORE could be next on the chopping block. Shulkin has been badly hobbled by an inspector general report that found he misused taxpayer money for lavish vacations. Shulkin has also been clashing with Trump political appointees on his own staff. The New York Times reported on Tuesday evening that Shulkin could be replaced by Energy Secretary Rick Perry Rick PerryOVERNIGHT ENERGY: Democrats push resolution to battle climate change, sluggish economy and racial injustice | Senators reach compromise on greenhouse gas amendment stalling energy bill | Trump courts Florida voters with offshore drilling moratorium OVERNIGHT ENERGY: Trump signs major conservation bill into law | Senate votes to confirm Energy's No. 2 official | Trump Jr. expresses opposition to Pebble Mine project Senate votes to confirm Energy's No. 2 official MORE.

National security adviser H.R. McMaster has been on thin ice for some time. Like Tillerson, he has never clicked with the president.

Trump has long expressed his frustration with Attorney General Jeff Sessions Jefferson (Jeff) Beauregard SessionsGOP set to release controversial Biden report Trump's policies on refugees are as simple as ABCs Ocasio-Cortez, Velázquez call for convention to decide Puerto Rico status MORE, blaming him for Robert Mueller Robert (Bob) MuellerCNN's Toobin warns McCabe is in 'perilous condition' with emboldened Trump CNN anchor rips Trump over Stone while evoking Clinton-Lynch tarmac meeting The Hill's 12:30 Report: New Hampshire fallout MORE’s special counsel investigation and fuming that he has not done enough to investigate Democrats.

And chief of staff John Kelly John Francis KellyMORE, once viewed as untouchable, has been under fire for his defense of a senior aide who resigned after being accused of domestic abuse by both of his ex-wives. The president is also believed to be frustrated by the narrative in the press that Kelly acts as his minder.

Trump has developed a reputation for venting against those who displease him, allowing them to twist in the wind with their futures in doubt rather than firing them outright.

But some in Trump’s inner circle think the president could use the momentum from Tillerson’s ouster for a purge.

“He needs to spend every day this week cleaning house so that the public and the press are so overwhelmed by the changes that there’s not enough time to absorb them all,” said one top Republican with deep ties to the administration. “That way, three weeks from now, it’s over, the Band-Aid is off and we’re back to focusing on the agenda.”

While the Tillerson news was cheered at the White House, the seemingly constant state of upheaval and turnover in the West Wing has been demoralizing to staff.

On Tuesday, the White House was reeling from the loss of John McEntee, Trump’s personal assistant, who was well-liked in the West Wing and close with the president. McEntee appears to be the latest casualty of Kelly’s enforcement of the security clearances process.

Other recent departures include communications director Hope Hicks Hope Charlotte HicksSenate intel leaders said Trump associates may have presented misleading testimony during Russia probe: report Cuomo turned down Trump invitation to participate in April press briefing: report Trump shakes up White House communications team MORE, staff secretary Rob Porter, senior adviser Jared Kushner Jared Corey KushnerAbraham Accords: New hope for peace in Middle East Tenants in Kushner building file lawsuit alleging dangerous living conditions Trump hosts Israel, UAE, Bahrain for historic signing MORE’s spokesman Josh Raffel and Kushner’s longtime family friend Reed Cordish. Those departures have left the White House with big shoes to fill in key roles.

“It’s one thing when it’s expected, no one will shed a tear over Tillerson,” said one GOP operative with close ties to the White House. “But when it’s unexpected, like with McEntee — the punch that hurts the most is the one you don’t see coming. That’s the kind of thing that shakes people to their core.”

The Hill asked a White House official on Tuesday what other changes were ahead, considering it is still so early in the week.

“I know, it feels like Friday,” the official said.

While Tillerson’s surprise ouster came as good news to the president’s allies, the sudden announcement and ensuing back and forth with the State Department had a whiff of chaos to it.

Trump announced over Twitter that Tillerson would be replaced by Pompeo moments after The Washington Post reported it.

“Rex and I have been talking about this for a long time,” Trump told reporters.

But Goldstein, the State Department spokesman, blasted out an email to reporters saying the move had come as a surprise to Tillerson.

The White House promptly fired Goldstein and scrambled to produce its own version of events.

Officials said Kelly called Tillerson twice between Friday and Sunday to tell him that he would be replaced upon his return from Africa.

“They wanted to let him know once the decision had been made, but waited until he got back to make an announcement,” an administration official said.

Speaker Paul Ryan Paul Davis RyanKenosha will be a good bellwether in 2020 At indoor rally, Pence says election runs through Wisconsin Juan Williams: Breaking down the debates MORE (R-Wis.) was informed of the decision on Monday during a conference call with Trump and Kelly.

That message did not trickle down to staff at State, sources tell The Hill, as Tillerson’s chief of staff Margaret Peterlin was pushing to hire new personnel on a conference call with White House officials as recently as Monday, apparently unaware that her boss had effectively been relieved of his duties.

Still, State Department career staff members had for months imagined Tillerson's tenure would be short-lived and had even been wagering on how quickly it might happen.

In the past year, department staffers described the secretary as remote, secluded, unapproachable and opaque with underlings not in the upper echelons of his team.

“As secretary of State, you usually have a base of support that comes either from the foreign policy establishment, the foreign service crowd, the political crowd or the press,” said the senior Republican. “I’ve never seen someone so brilliantly unite all of those factions against them the way Tillerson did.”

Scott Wong contributed