There are already evidence of how space permanence affect living being, flies included. For example, when Fruit Flies were sent to Earth orbit onboard Space Shuttle Discovery in 2006, they all experienced a decrement in their immune function, no matter if their stay was fairly short (only 13 days). The ISS experiment will provide many precious indications over a quite longer period. The flies will be living in a special Fruit Fly Lab, “and experiencing the same space radiation and microgravity as their human counterparts. Cameras will record the behavior and appearance of these miniature astronauts; and at intervals some of them will be frozen and returned to Earth for analysis.” (NASA Science, 8 July 2014).