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Meghan Markle forces her Canadian staff to wear latex gloves over coronavirus fears — while husband Prince Harry feels “helpless” being isolated more than 4,500 miles away from his aging royal family, according to a report.

The Duke and Duchess of Sussex are determined to do something to help during what they deem a “mental health crisis” with the shocking change in life brought about by the pandemic, a close friend told DailyMail.com.

It is also a crisis for them while they are in lockdown on Canada’s Vancouver Island — with Harry feeling “a bit helpless and isolated out in the middle of nowhere” after leaving the UK, according to the report.

He is particularly worried for his 71-year-old father, Prince Charles, and his grandmother, Queen Elizabeth II, who turns 94 next month, and has been in contact to urge them to “stay safe and to take extra precautions,” the insider said.

Markle, meanwhile, makes “everyone on their team, the people who buy groceries and run errands, wear latex gloves at all times and are to follow a strict hygiene protocol,” the friend told the site.

“Only a select few will be able to interact with her, Harry and Archie. She said she’s keeping it to a bare minimum.”

Despite finding their final royal tour of the UK “bittersweet,” the Sussexes are “grateful” they got to spend time with Harry’s family “before all this insanity began,” the insider told the site.

The 38-year-old duchess is determined to help with the crisis, the friend said.

“Meghan said just because they are isolating themselves, it doesn’t mean they can’t help. They aren’t just sitting around at home doing nothing,” the friend told the Mail.

“Meghan told her inner circle that what’s happening in the world right now is a mental health crisis.

“She said they are working with a mental health nonprofit to create some sort of online support system for those most vulnerable, like new mothers suffering from postpartum depression.

“People who lack support systems need reassurance that they are not alone.”