It is hard to come back from calling someone a “cancer,” and Landon Collins isn’t trying to retreat.

The morning after the Giants standout safety went public in his blasting of teammate Eli Apple, Collins showed no sign of remorse.

“I feel like Eli Apple has checked out,” Collins told ESPN’s Josina Anderson. “… If you go back to the game on Sunday, Eli was sitting down on the sideline. That’s not what we need right now.”

Sunday in Arizona, Apple played just seven snaps — all on special teams — as the cornerback was taken off his defensive assignments, the latest sad turn in a season filled with them.

The 2016 10th-overall pick has had a sophomore season from hell, which has included a near film-session walk-out while being criticized, according to The Post’s Paul Schwartz, and being inactive for four straight games as a healthy scratch. His personal life also has reached a rough stretch, with his mother undergoing brain surgery. Collins would not allow him that excuse.

“We all go through our own family things,” Anderson relayed from Collins, who said he has had his own issues in the home, but “I have to go to work and be a professional.”

In case going on ESPN NY radio for the world to hear his complaints wasn’t enough evidence, Collins, the Giants’ lone Pro Bowler, appears to be finished with Apple.