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JERUSALEM — Israel could respond to any Iranian attack on it from Syria by toppling Syrian President Bashar al-Assad’s government, an Israeli security cabinet minister said on Monday, hinting that Assad himself may be targeted for assassination.

Israel and Iran have traded blows over Syria since February, stirring concern that major escalation could be looming ahead of next week’s review decision by U.S. President Donald Trump on the 2015 international nuclear deal with Tehran.

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On April 9, an air strike killed seven Iranian Revolutionary Guards Corps members at the Syrian base. Tehran blamed Israel and vowed unspecified retaliation, drawing Israeli counter-threats to broaden attacks on Iranian military assets in Syria.

Sharpening these warnings, Energy Minister Yuval Steinitz said on Monday that Assad may find himself in Israel’s sights.

“If Assad allows Iran to turn Syria into a military vanguard against us, to attack us from Syrian territory, he should know that would be the end of him, the end of his regime,” Steinitz told the Ynet news site.