"We meet on a regular basis with our Marvel team, and we've plotted out Marvel movies that will take us well into the next decade," said Iger. "I'm guessing we will try our hand at what I'll call a new franchise beyond Avengers, but that doesn't necessarily mean you won't see more Avengers down the road. We just haven't made any announcements about that."

Iger noted that the 19 films in the Marvel Cinematic Universe have earned more than $16 billion globally. Disney is riding high as Marvel's Avengers: Infinity War continues its box-office rampage — andnoted that the 19 films in the Marvel Cinematic Universe have earned more than $16 billion globally.

Iger said that the goal with Avengers 4, which filmmakers Joe and Anthony Russo shot back-to-back with Infinity War, was to "have a significant conclusion" to the story that began with 2008's Iron Man. But he wouldn't rule out more Avengers movies down the road.

"Given the popularity of the characters and given the popularity of the franchise, I don't think people should conclude there will never be another Avengers movie," Iger said.

One of the challenges with Infinity War was the scale of its cast, noted Disney CFO Christine McCarthy.

"I think the outstanding performance is nothing short of stellar," she said, adding "there is one difference in this movie … that's the size of the cast. ... Because of the size of the cast involved and the cost of the movie, the scale, the magnitude, while this film is going to be very profitable, it may not be on the same return level as some of the other films, because of the sheer scale of it."

Disney is working on acquiring 21st Century Fox assets, which would give the studio rights to classic Marvel characters such as X-Men and Fantastic Four.

Infinity War has made more than $1.1 billion worldwide. Here's what's officially on the docket for Marvel: Ant-Man and the Wasp (July 6), Captain Marvel (March 8, 2019), Avengers 4 (May 3, 2019), and a Spider-Man: Homecoming sequel (July 5, 2019). It also has carved out nine dates for untitled Marvel movies: May 1, 2020; July 31, 2020; Nov. 6, 2020; May 7, 2021; July 30, 2021; Nov. 5, 2021; Feb. 18, 2022; May 6, 2022; and July 29, 2022.