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President Trump's concerned Robert De Niro is suffering brain damage from his boxing movies, and thinks that's the ONLY explanation for the Oscar winner saying, "F**k Trump" at the Tony Awards.

The Prez turned his attention to De Niro's diss after finishing up with Kim Jong-un in Singapore ... saying De Niro is a "low IQ individual" who "has received to many shots to the head by real boxers in movies."

Yes, call the Irony PD -- POTUS used the wrong "to" while calling out Bobby D's IQ.

Robert De Niro's hatred for Trump is one of the funniest things in the world 😂😂😂



(Shoutout Australia for not censoring curse words on television)pic.twitter.com/pTla4xXeVM @RobbieBarstool

Anyway, 45 went on to suggest De Niro's ignoring great economic and employment numbers, and ended his brief Twitter rant with, "Wake up Punchy!"