Charlie Sheen is HIV-positive, two sources confirm to E! News.

Amid rumors about his health, Sheen is scheduled to give a live, in-studio interview with Today's Matt Lauer in Studio 1A Tuesday. A press release issued Monday said the 50-year-old actor "will make a revealing personal announcement."

The interview will be available on Today.com after it airs.

Reps for Sheen did not respond to E! News' request for comment.

The troubled actor has five children, ranging in age from 6 to 30, in addition to three ex-wives: Donna Peele (1995-1996), Denise Richards (2002-2006) and Brooke Mueller (2008-2011). E! News has learned that both Richards and her two daughters with Sheen, Sam and Lola, are HIV-negative.

Sheen spent most of 2015 out of the spotlight. Aside from a guest appearance on the ABC sitcom The Goldbergs in February, he has not appeared regularly on television since FX's Anger Management ended in December 2014.