President Donald Trump on Tuesday blasted influential conservative donors Charles and David Koch, dubbing them a “total joke” who are “against Strong Borders and Powerful Trade.”

The president’s harsh words for the powerful brothers came a day after they signaled an intention to shift away from their practice of pushing for Republican-only bills and policy solutions, saying they would seek and push bipartisan proposals, which is seen as a repudiation of Trump.

It also came a day after a conservative advocacy organization backed by the Koch brothers announced it would not support Rep. Kevin Cramer in the North Dakota Republican’s Senate bid.

Trump dubbed the duo the “globalist Koch Brothers,” drawing a distinction from his nationalist “America first” message, and philosophy that is the basis of his governing approach and leads him to constantly play to his conservative base.