Video report by ITV News Correspondent Sejal Karia

Two teenage boys, aged 14 and 13, have died following a major incident in Sheffield that saw six children rushed to hospital.

The four other children, aged 11-years-old, 10-years-old and three-years-old and seven-months-old remain in hospital receiving treatment.

Police were called at around 7.30am today (24 May) to reports of concerns for safety at a property on Gregg House Road, Shiregreen.

Police have cordoned off the street after six children taken to hospital in major incident in Sheffield Credit: ITV Calendar

The house where the incident is believed to have taken place is just 100 metres from Hartley Brook Primary Academy, with the air ambulance landing in the school playground.

Police said the incident is not related to the school, which is open as normal.

Yorkshire Ambulance Service and Yorkshire Air Ambulance attended and transported six children to hospital. Credit: ITV Calendar

A 37-year-old man and a 34-year-old woman have since been arrested on suspicion of murder in connection and remain in custody at this time

The cause of death has not yet been established and a post-mortem examination will be carried out in due course.

Family have been informed and are receiving support from specially trained officers.

Local resident Aaron Brunskill said residents came out into the street at 8am to find around 15 police cars and four ambulances.

He said:

The police weren't telling us anything. Aaron Brunskill

Detective Chief Inspector Simon Palmer, investigating, said:

Detectives and specialist officers remain in the Gregg House Road area carrying out enquiries and we are working hard to ascertain the exact circumstances surrounding this incident. Detective Chief Inspector Simon Palmer