Samir Nasri is set to miss Manchester City's Champions League tie with Sevilla as the Premier League leader's injury problems have worsened.

Nasri, 28, had missed City's previous two games but suffered another hamstring injury during his cameo in Saturday's 5-1 win over Bournemouth.

And the France international midfielder is set to be one of six players who are sidelined for the clash with the Europa League winners at the Etihad Stadium on Wednesday.

Sergio Aguero, David Silva, Fabian Delph, Gael Clichy and Aleksandar Kolarov are all injured and while young striker Kelechi Iheanacho is fit, he is ineligible in Europe.

City are hoping Nasri's injury will not result in a long-term absence and he was able to complete the Bournemouth game.

Manager Manuel Pellegrini told a news conference: "Nasri had a problem with his hamstring. I think it will be very difficult for him [to play against Sevilla].

"Unfortunately we knew that he was feeling something after we made the third change, but he didn't run too much. He stayed in the middle so we'll see in the next day what happens with him."

Nasri has only started two games for City this season but, with Silva already missing, his absence means Pellegrini has little back-up for his three attacking midfielders: Raheem Sterling, Kevin De Bruyne and Jesus Navas.