Reports on Friday revealed that an administration official said Secretary of the Department of Homeland Security Janet Napolitano will resign, according to reports from Reuters, the New York Times and the Associated Press.

The AP reported that Napolitano is leaving to take a senior position in the University of California system and told senior staff about her departure at a meeting Friday morning. CNN confirmed that Napolitano will take over as president of the UC system.

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Napolitano previously served as governor of Arizona before she was tapped by President Barack Obama to be the third secretary of the federal government’s newest department. Her departure in the state led to the rise of Republican Gov. Jan Brewer, who had served as lieutenant governor, and a slew of conservative legislation in recent years, including anti-immigrant law SB 1070 and a law banning abortion after 20 weeks that redefined the beginning of a pregnancy as earlier than other legislation.

Update (11:33 a.m.): According to Foreign Policy magazine, Napolitano’s resignation means that now the top 15 posts at the Department of Homeland Security are now vacant.