Andrew Mallard, the Australian man who spent over a decade in jail for a murder he did not commit, has been killed in a hit-and-run crash on Hollywood's iconic Sunset Boulevard.

Mr Mallard spent 12 years in a West Australian prison after he was wrongfully convicted of murdering jeweller Pamela Lawrence at her shop in Mosman Park in Perth on May 23, 1994.

Mr Mallard had his conviction quashed by the High Court in 2005 and received a $3.25 million ex gratia payment, but tragedy struck again in the early hours of Thursday morning, local time, as he crossed Sunset Boulevard in Hollywood, an area well known for its restaurants and bars.

The LAPD believes the driver was heading east on Sunset Boulevard, and Mr Mallard was walking south across Sunset Boulevard along Formosa Ave about 1.30am when the crash occurred.