The California State Athletic Commission was thrown into the center of the TRT debate by Chael Sonnen back around UFC 117, and has now taken steps to allow for TUE's for TRT and marijuana. SI.com passes along the information regarding the state's amendment:

The California State Athletic Commission voted on Monday to approve an amendment that allows therapeutic use exemptions (TUE) for combat sports’ athletes who use drugs currently banned by the state agency for medical purposes, including testosterone and marijuana. To be adopted into state law, the amendment’s verbiage must now be reviewed and approved by the Department of Consumer Affairs and then the state’s Office of Administrative Law, a process that could take months or even years, if it passes at all.

According to CSAC executive officer George Dodd, TUE's have been granted to fighters with the supporting medical documentation in the past, including Dan Henderson before his UFC 139 bout with Mauricio "Shogun" Rua. This amendment will basically allow to the commission to streamline the process, which is "loosely modeled" on what WADA uses. Henderson's application was used as a test case, according to Dodd:

Dodd told SI.com in December that Henderson’s rigorous approval process served as a test case that the commission used to evaluate its proposed TUE requirements. Like Henderson, one of three fighters approved for a testosterone TUE in Nevada, Dodd said future TUE candidates would need to provide extensive medical records documenting past use of the drug for medical purposes. For a testosterone exemption specifically, Dodd said an applicant would be asked to provide blood tests prior to (30 days before) and after a contest to ensure levels were within acceptable margins. Dodd said that all materials submitted would be reviewed by the CSAC’s medical advisory board, which added an endocrinologist to its ranks on Monday for such cases.

Nothing regarding a TUE for marijuana was mentioned in the article, other than that the amendment will cover that as well. While TRT is very controversial in MMA, marijuana usage has been too (such as the case of Nick Diaz post-UFC 137) and it will be interesting to see how that process will work for fighters.