Here's a weird fact about this Sunday's looming divisional showdown between the Buffalo Bills and the New England Patriots: new starting quarterback Kyle Orton will be the Bills' fourth different starting signal-caller in their last four games against their division rivals.

On November 11, 2012, Ryan Fitzpatrick made his last start against New England as the Bills' top gun, completing 27-of-40 passes for 337 yards with two touchdowns and a late interception in a gutting, 37-31 loss to the Patriots in Foxboro.

Fitzpatrick was released four months later, making way for first-round pick EJ Manuel to start last year's season opener, a home affair with the Pats. In another gutting loss, this time 23-21 on a last-second Patriots field goal, Manuel was efficient in his pro debut, completing 18-of-27 passes for 150 yards with two touchdowns and no interceptions.

By the time Week 17 of the 2013 season rolled around, however, Manuel was done for the year with a knee injury, which thrust Thad Lewis into the lineup for the Bills' finale in New England. He completed 16-of-29 passes for 247 yards with a touchdown and no picks in a 34-20 loss, in which Buffalo's defense was ripped to shreds on the ground by the Patriots' running game.

Today, we're more than a week removed from Orton replacing Manuel as the Bills' starting quarterback. He'll be the latest in a long line of Bills quarterbacks to have taken on Tom Brady and the Patriots; hopefully, he'll be one of the very few to manage to emerge victorious.