NASA TV will be covering the launch from the Kennedy Space Center, online, at that time.

Orlando Sentinel:

Discovery is set to launch at 4:50 p.m., with a crew of six commanded by Steve Lindsey, a retired Air Force colonel. Its 11-day mission – ferrying supplies and a humanoid robot to the International Space Station — will be its 39th since 1984, and its last.

The mission marks the beginning of the end of the 30-year space shuttle program. Discovery, arguably the most-storied and versatile spaceship in the fleet, should be followed by Endeavour in April, and, if all goes well, Atlantis as early as June. Then, for the first time in nearly 60 years, the United States will have no government-owned rocket ready to launch.