Transgender people and their needs remain little understood, not only by health-care providers but also more generally in society. An absence of appropriate information, together with misinformation, breeds stigma and prejudice, leading to discrimination, harassment, and abuse, with alarming consequences for transgender people’s health and wellbeing.

This Series is an effort to understand, and provide a framework to improve, the health and lives of transgender people globally. The three papers in this Series examine the social and legal conditions in which many transgender people live, clinical care considerations and service delivery models in transgender health, and the global health burden facing transgender populations, including the specific contexts and multiple determinants of health affecting them.