Still perfect

Denver was handed its first loss of the season at Indianapolis, but Carolina and New England joined Cincinnati at 8-0. It’s the most 8-0 teams in a single season in NFL history.

A lot of yards

Antonio Brown and DeAngelo Williams combined for a historic performance in Pittsburgh’s 38-35 victory against Oakland. Brown accumulated 306 scrimmage yards while Williams was credited with 225, making the Steelers the first team in NFL history to have one player with at least 300 yards and another with at least 200 in the same game.

Streaks & stats

Carolina’s Cam Newton threw for three touchdowns and ran for a score, leading the Panthers to a 37-29 win over Green Bay. It was Newton’s 15th career game with multiple touchdown passes and a rushing TD, joining Hall of Famers Steve Young (17) and Fran Tarkenton (16) as the only players with as many such games. … Todd Gurley’s streak with 125-plus yards rushing at four straight games. The rookie star for St. Louis gained 89 yards and a touchdown in a 21-18 overtime loss to Minnesota.

Milestones

Bills running back Karlos Williams returned after missing three games with a concussion and became the seventh player to score a touchdown in each of his first five NFL games. The record is by New England’s Robert Edwards, who scored in his first six games in 1998. … Indianapolis quarterback Andrew Luck threw for two scores in the Colts’ 27-24 win against Denver, reaching 100 career touchdown passes in his 55th game. Only Dan Marino, Kurt Warner and Johnny Unitas reached the milestone in fewer games.

Injuries

Pittsburgh quarterback Ben Roethlisberger threw for 334 yards and two touchdowns before he departed in the fourth quarter with a left foot injury. … The Vikings lost Teddy Bridgewater to a concussion in the fourth quarter of a 21-18 overtime win against St. Louis. The quarterback was sliding on a scramble when defensive back Lamarcus Joyner launched himself and hit him in the head. … Jets center Nick Mangold left with a neck injury. New York also lost cornerback Antonio Cromartie to a thigh injury. … New England running back Dion Lewis left in the third quarter with what appeared to be a serious left knee injury.