National Public Radio, citing an unexpected revenue shortfall, said Wednesday that it would cut 64 jobs, or about 7 percent of its work force of 889, and would cancel two weekday programs, “Day to Day” and “News & Notes.”

The cutbacks, which come even as NPR is reaching what it said is a near-record audience of 26.4 million listeners a week, include 22 employees at the canceled programs, which will end March 20; six reporters and correspondents elsewhere; and one digital media position.

In addition to the job cuts, 21 open positions will not be filled. Expenses will be reduced in reporting, production, station services, communications, administration and travel, and NPR will also draw on its operating reserves to make up for what is expected to be a $23 million revenue shortfall, leaving it with projected revenue of $145 million in the fiscal year ending next September.

NPR was projecting a $2 million deficit in July when the budget was approved, and, citing the economic slowdown, it canceled the fledgling morning program “The Bryant Park Project.” Since then, as the economy worsened, corporate sponsorships in particular have dropped precipitously, to a projected $33 million for the year instead of the $47 million budgeted, NPR executives said.