Almost two years after his sister's death, Logie award-winning actor Samuel Johnson is continuing their campaign to raise millions of dollars for cancer research.

Connie Johnson was diagnosed with a bone tumour in her leg when she was 11 and a decade later, cancer was found in her womb.

Since receiving her terminal diagnosis in 2010, the mother-of-two and her brother devoted themselves to raising money for cancer research.

Together they created the Love Your Sister campaign to raise money for cancer research.

Before her death in 2017, Ms Johnson was awarded a Medal of the Order of Australia for her service to those with breast cancer.

Almost two years on, Samuel Johnson is continuing their quest to raise millions for cancer research by campaigning in communities around Queensland in the first leg of a national tour.

"I'm marketing this trip as a lap of honour for my sister Connie," he said.

"We together promised the country that we'd raise $10 million for cancer research.

"We're on 9.6 and I'm going to come good on that promise.

"We started in the Gold Coast and we headed up all the way up to Cairns and now we're [travelling] back, but we're on the road for two years."

Samuel Johnson with his late sister Connie at a previous Love Your Sister charity event. ( ABC News: Diana Hayward )

Hairdressing industry joins cause

Samuel Johnson visited Gladstone on the weekend for the Mocha Angels' Pyjama Day fundraising event involving 140 beauty salons across the country.

"I'm getting my hair cut from Rex Silver because I hate cancer and I need a haircut," he said.

"I'll do anything for a donation."

Samuel Johnson having his hair cut by Rex Silver. ( ABC Capricornia: Erin Semmler )

Mr Silver, a salon owner, said Johnson's focus on awareness suited the industry perfectly.

"We have contact with so many people, everyone gets their hair cut," Mr Silver said.

"I think having hairdressers onboard anything would be a bonus to anyone that wants to get their message out there.

"We just love talking about stuff and we're talking to people every day so it's a great platform."

Pyjama Day involved 140 hair salons across Australia for Johnson's Love Your Sister campaign. ( ABC Capricornia: Erin Semmler )

Mocha Angels' Linda Woodhead said she had been gathering hairdressers across the country to support Love Your Sister for three years.

"I felt that the hair and beauty industry specifically, everyone's been touched by cancer in some way, being a beauty industry, a lot of women are involved," she said.

"Seventy salons joined with us last year in May for a special Pyjama Day and fundraising for the whole month.

"We raised $48,000 and this year we've got 140 salons, so we've doubled in size.

The 140 salons have pledged $100 to be part of the effort, with some owners donating all salon tips and matching that with another donation, while others are selling baked goods.

"My aim is to double our donation as well, our goal is $100,000," Ms Woodhead said.

Generosity in small communities

Mr Johnson has already campaigned in more than 800 communities and is well known for his 15,000-kilometre unicycle trip during which he raised almost $1.5 million in 365 days.

He started a two-year tour in May to raise the remainder of the $10 million.

Linda Woodhead established Mocha Angels, a beauty industry group raising money for Love Your Sister. ( ABC Capricornia: Erin Semmler )

"I'm about two or three weeks away from finishing my Queensland leg and then it's off to all the other states," he said.

"I find that most charities in Australia are far too city-centric, the regions are where the heartbeat is.

"I'm constantly astounded by the generosity of the smaller communities and I prefer to stay away from the cities to be honest.

"It's really important to me as part of my job that I [visit the regions], I'm a ground-level guy and this work is best done face to face."

Push for personalised medicine

Johnson is advocating for personalised medicine for all new cancer patients, no matter where they live or the type of cancer they have.

This would mean patients receive medication tailored to them according to their genetic makeup.

"When my sister was diagnosed with breast cancer, the same thing happened to her as any other breast cancer patient basically," he said.

"They tried her on tamoxifen. Now tamoxifen is an amazing drug, but it only works in about 72 per cent of cases.

"So it takes three months to determine the efficacy of a line of treatment."

Johnson's is fundraising across Queensland before heading to other states on a two-year tour. ( ABC Capricornia: Erin Semmler )

Johnson said his sister went through three months of tamoxifen, which resulted in a false line of treatment.

He said his next move was to push for personalised medicine for all cancer patients, so they could be treated with suitable medicine as soon as possible.

Cancer Council Australia CEO Sanchia Aranda said cancer treatment was becoming more personalised, but trials were still underway to ensure the safety and effectiveness of such treatment.

"Personalisation is moving more in this direction as we learn more about potential changes at the molecular level and … treatments for these specific changes are developed, and we know more about predicting which patients will benefit from these 'targeted' treatments," Professor Aranda said.

"However, while the idea of personalised therapy is a good one, there remain limits to our understanding of how to target [it].

"While in the future it is likely all cancers will undergo genome sequencing to help with personalised treatment, currently there are limits to our knowledge that preclude this from happening for everyone.

"This is an area where research is rapidly developing."