Sen. Marco Rubio Marco Antonio RubioFlorida senators pushing to keep Daylight Savings Time during pandemic Hillicon Valley: DOJ indicts Chinese, Malaysian hackers accused of targeting over 100 organizations | GOP senators raise concerns over Oracle-TikTok deal | QAnon awareness jumps in new poll Intelligence chief says Congress will get some in-person election security briefings MORE (R-Fla.) announced Monday morning that he would support President Trump Donald John TrumpHR McMaster says president's policy to withdraw troops from Afghanistan is 'unwise' Cast of 'Parks and Rec' reunite for virtual town hall to address Wisconsin voters Biden says Trump should step down over coronavirus response MORE's pick to lead the State Department, removing the last significant stumbling block to the nomination.

Rubio, who aggressively questioned secretary of State nominee Rex Tillerson during his hearing earlier this month, had been the lone Republican holdout on the Senate Foreign Relations Committee.

"Given the uncertainty that exists both at home and abroad about the direction of our foreign policy, it would be against our national interests to have this confirmation unnecessarily delayed or embroiled in controversy," Rubio said in a statement on his Facebook page.

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"Therefore, despite my reservations, I will support Mr. Tillerson’s nomination in committee and in the full Senate."

Because of the committee's structure, a defection by even one Republican senator would have denied Tillerson the majority vote he needed to easily move to a floor vote. However, as Rubio weighed his decision, Committee chairman Bob Corker Robert (Bob) Phillips CorkerHas Congress captured Russia policy? Tennessee primary battle turns nasty for Republicans Cheney clashes with Trump MORE (R-Tenn.) told reporters that he'd still be able to bring Tillerson up for a floor vote regardless of whether he wins the majority in the committee.

Now that Rubio joins Republican Sens. Lindsey Graham Lindsey Olin GrahamThe Hill's Campaign Report: Arizona shifts towards Biden | Biden prepares for drive-in town hall | New Biden ad targets Latino voters Senate Democrats' campaign arm announces seven-figure investment to boost Graham challenger Graham: Comey to testify about FBI's Russia probe, Mueller declined invitation MORE (S.C.) and John McCain John Sidney McCainThe electoral reality that the media ignores Kelly's lead widens to 10 points in Arizona Senate race: poll COVID response shows a way forward on private gun sale checks MORE (Ariz.) in support, Tillerson is expected to be confirmed once the full Senate holds its vote.

The Foreign Relations panel plans to hold its vote Monday to move Tillerson toward confirmation on the chamber floor.

Tillerson came into his nomination hearing facing a slew of questions over his ties to Russia as the former CEO of Exxon Mobil. But while virtually all of the Democrats on the committee pushed Tillerson during his hearing, Rubio's assertive questioning stood out among his Republican peers.

The Florida senator criticized him for refusing to label China and Saudi Arabia as human rights violators, refusing to say Russia committed war crimes in Syria and waffling over whether Russian President Vladimir Putin has killed dissidents and journalists.

Those questions, along with his public wavering about his vote, drove speculation that Rubio was laying the groundwork to vote against Tillerson and potentially jeopardize the nomination.

The Democratic National Committee chided Rubio for "rolling over for Donald Trump" in a pointed statement just minutes after Trump's former GOP primary foe announced his decision.

“By ignoring his serious reservations about Tillerson’s connections to Vladimir Putin, Marco Rubio is not only rolling over for Donald Trump, he’s earning the nickname Trump gave him: Little Marco," DNC senior adviser Zac Petkanas said.

Rubio pointed to those disagreements in his statement, calling Tillerson’s “answers on a number of important questions ... troubling." He added that he remains "concerned" about the country's future foreign policy direction "in the years to come," warning against "a foreign policy that too often sets aside our values and our historic alliances in pursuit of flawed geopolitical deals."

He said, however, that his concerns were outweighed by Tillerson's "extensive experience and success in international commerce" along with Rubio’s desire to give Trump "deference" in filling his inner circle.

But Rubio added that he would not give Trump's State Department picks "the same level of deference" in the future.