Herman Cain Julie Dermansky | Corbis News | Getty Images

WASHINGTON — Republican Sen. Kevin Cramer, N.D., on Thursday became the fourth member of his party's caucus to tell reporters he would vote against a nomination for former pizza executive Herman Cain to join the board of the Federal Reserve. "If I had to [vote] today, I would vote no" on Cain, Cramer told reporters Thursday on Capitol Hill. Cain has yet to be formally nominated by President Donald Trump, but last week Trump announced that Cain was his pick to fill one of two open seats on the central bank's board. Trump intends to nominate conservative economist and author Stephen Moore for the other vacant spot.

Cramer's announcement all but doomed Cain's chances of being confirmed by the Senate if Trump were to formally nominate him. Earlier this week, GOP Sens. Lisa Murkowski of Alaska and Cory Gardner of Colorado, and newly minted Sen. Mitt Romney of Utah all told reporters they could not support a nomination of Cain. With only 53 Republicans in the Senate, opposition from four of them would mean that Cain could only count on 49 votes to confirm him, presuming, of course, that no Democrats crossed the aisle to support him. Without a 51-vote majority, Cain could not be confirmed.

Sen. Kevin Cramer, R-N.D. Tom Williams | CQ-Roll Call Group | Getty Images