Upper East Side residents sued to stop construction of a 1.1 million-square-foot medical complex on East 73rd Street near the FDR Drive, claiming the project will turn the neighborhood into Bedpan Alley.

A dozen neighbors, who live in luxury buildings in the East 70s, object to the $226 million behemoth project because it will block their sweeping East River views and choke the area with 8,000 more people and 1,600 additional vehicles daily, according to the Manhattan civil suit.

The group, Residents for Reasonable Development, accuses city agencies of granting special permits for the complex that will include a 350-foot-tall Hunter College nursing school and a 450-foot-tall Memorial Sloan-Kettering clinic. The tallest tower will reach 45 stories.

“The approvals given by the City Planning Commission and City Council were not in accordance with a well-considered plan or to serve the general welfare, but were given for the sole benefit of [the developers], in violation of the law,” the suit, filed Friday, says.

Construction is scheduled to start next year, according to the hospital, which is also a defendant in the suit.

Two of the residents involved in the suit, Sarah Chu and Neal Biangiardo, live at 509 E. 77th St. with their one-year-old daughter.

“The project will disrupt the existing largely residential community in which they live by injecting massive institutional uses incompatible with their surroundings,” they claim in the suit.

Previously, the site was as Department of Sanitation garage that shut down in 2008.

The residents claim a two-month bidding process for the site was only open to health-care, education or scientific research facilities, cutting more attractive neighbors like residential buildings out of the mix.

The effect is to engulf the area in what has become known as Bedpan Alley or Cancer Alley—a stretch of hospitals starting at E. 60thStreet that includes large institutions like New York Presbyterian and Rockefeller University.

Bloomberg has hailed the project as a state-of-the-art facility that would create 3,200 construction jobs and 830 full time positions.

A spokeswoman for the city’s Law Department said “we will review the petition once we are served.”

A rep for the hospital said the project has been supported by the local community board and “has gone through extensive review.”

“We think that it represents a step forward for New York,” she said.