So the magnificent bastards at THQ Nordic have revealed a remake for Destroy All Humans! with a trailer that’s one part alien invasion b-movie and one part Rammstein dance party. As a result, videos are popping up all over YouTube of people making reactions, as well as various channels doing playthroughs in anticipation. While watching a particular let’s play, though, I noticed the gamer making simple and easily correctable mistakes and I thought it would be a great idea to make a quick list of tips for beginners, or YouTubers who are likely to miss out on details while commentating.

You’ll be asked to grind for DNA between several key missions, and DNA is required to purchase upgrades from Pox’s Lab. It’s best to do this early on and there are a few ways to do so. One, sandbox challenges which appear in the world as orange beams of light. Two, using charged anal probe shots on human enemies. Three, finding collectible probes.

How much DNA a human gives you depends on their type and whether or not they’re alive. Living humans give more DNA, so use extract or the anal probe. Civilians on average only give 10 DNA, unless they’re a Town Crazy or a unique model like Martha Turnipseed. Scientists usually give anywhere from 50 - 125 DNA. Farmers, cops and soldiers usually each give 25 - 50. Majestic Agents and Psy Agents can give anywhere from 50 to 200 DNA.

The extract and hypno commands only require one button press, but their speed and effectiveness can be increased by mashing the button repeatedly. This is necessary for stronger enemies.

HoloBob uses concentration. Concentration can be replenished by cortex scanning humans of any kind. HoloBob won’t work around Majestic Agents and will flash red if you’re getting too close to one.

Crypto can’t swim, avoid entering the water at all costs. Humans can’t swim either, and PKing them into water while HoloBobbed is a great way to get rid of enemies without raising the alert level.

PK cannot be used on vehicles or robots without an upgrade. PK is a good way to quickly deal with robots, EMP mines and obstacles while HoloBobbed, as you can’t jump while in HoloBob.

Duck and Cover is an escort mission in which you must guide a truck carrying a nuclear payload to an airfield at the research base of Area 42. Some of the obstacles can be dealt with before the escort begins.

Majestic forcefields can be disabled by finding and destroying their control console. Hypnotizing specially marked NPCs is a good way to disable them while in disguise. The same is true for Tesla Coils. You can also use PK on Tesla Coil consoles to overload and destroy them.

Radioactive cows can be picked up with PK and used to destroy things in order to conserve ammo.

There is fall damage, manage your jetpack usage carfully. Sometimes it isn’t the best getaway strategy when you’re being overwhelmed. Though even when you’ve used up all 3 boosts you can continue to mash x to safely glide back to the ground. Get out of sight, use HoloBob on a pedestrian and then Hypno someone for a distraction. This is the best way to lower your alert level.



Upgrade the Zap-O-Matic before you upgrade anything else, as it doesn’t use ammo which makes it the most reliable on-foot weapon. The Death Ray is the saucer equivalent.

Wooden crates marked UFO contain randomized ammo, destroy them to get it. Ammo can also be found as pickups scattered around each sandbox.

Saucer pickups spawn in over destroyed buildings and landmarks.

Pay attention to the dialogue so you don’t miss your objectives. If you do miss your objectives you can check them in the pause menu.




And that’s it for now! Should I think of any more tips and tricks I’ll be sure to edit them in, but for now this should be enough to give all you intrepid invaders a better time of it! Happy probing!

