Aldridge G.M.

Podrebarac D.M.

Greenough W.T.

Weiler I.J. The use of total protein stains as loading controls: an alternative to high-abundance single-protein controls in semi-quantitative immunoblotting. J. Neurosci. Methods. 172 : 250-254 View in Article Scopus (281)

PubMed

Crossref

Google Scholar

Atshaves B.P.

Petrescu A.D.

Starodub O.

Roths J.B.

Kier A.B.

Schroeder F. Expression and intracellular processing of the 58 kDa sterol carrier protein-2/3-oxoacyl-CoA thiolase in transfected mouse L-cell fibroblasts. J. Lipid Res. 40 : 610-622 View in Article PubMed

Google Scholar

Atshaves B.P.

Storey S.M.

Petrescu A.

Greenberg C.C.

Lyuksyutova O.I.

Smith 3rd, R.

Schroeder F. Expression of fatty acid binding proteins inhibits lipid accumulation and alters toxicity in L cell fibroblasts. Am. J. Physiol. Cell Physiol. 283 : C688-C703 View in Article Scopus (47)

PubMed

Crossref

Google Scholar

Bordone L.

Cohen D.

Robinson A.

Motta M.C.

van Veen E.

Czopik A.

Steele A.D.

Crowe H.

Marmor S.

Luo J.

et al. SIRT1 transgenic mice show phenotypes resembling calorie restriction. Aging Cell. 6 : 759-767 View in Article Scopus (527)

PubMed

Crossref

Google Scholar

Bosma M.

Sparks L.M.

Hooiveld G.J.

Jorgensen J.A.

Houten S.M.

Schrauwen P.

Kersten S.

Hesselink M.K. Overexpression of PLIN5 in skeletal muscle promotes oxidative gene expression and intramyocellular lipid content without compromising insulin sensitivity. Biochim. Biophys. Acta. 1831 : 844-852 View in Article Scopus (69)

PubMed

Crossref

Google Scholar

Bu S.Y.

Mashek M.T.

Mashek D.G. Suppression of long chain acyl-CoA synthetase 3 decreases hepatic de novo fatty acid synthesis through decreased transcriptional activity. J. Biol. Chem. 284 : 30474-30483 View in Article Scopus (61)

PubMed

Crossref

Google Scholar

Buckland G.

Gonzalez C.A. The role of olive oil in disease prevention: a focus on the recent epidemiological evidence from cohort studies and dietary intervention trials. Br. J. Nutr. 113 : S94-S101 View in Article Scopus (66)

PubMed

Crossref

Google Scholar

Dai H.

Case A.W.

Riera T.V.

Considine T.

Lee J.E.

Hamuro Y.

Zhao H.

Jiang Y.

Sweitzer S.M.

Pietrak B.

et al. Crystallographic structure of a small molecule SIRT1 activator-enzyme complex. Nat. Commun. 6 : 7645 View in Article Scopus (83)

PubMed

Crossref

Google Scholar

Dalen K.T.

Dahl T.

Holter E.

Arntsen B.

Londos C.

Sztalryd C.

Nebb H.I. LSDP5 is a PAT protein specifically expressed in fatty acid oxidizing tissues. Biochim. Biophys. Acta. 1771 : 210-227 View in Article Scopus (156)

PubMed

Crossref

Google Scholar

Di Sante G.

Wang L.

Wang C.

Jiao X.

Casimiro M.C.

Chen K.

Pestell T.G.

Yaman I.

Di Rocco A.

Sun X.

et al. Sirt1-deficient mice have hypogonadotropic hypogonadism due to defective GnRH neuronal migration. Mol. Endocrinol. 29 : 200-212 View in Article Scopus (11)

PubMed

Crossref

Google Scholar

Estruch R.

Martínez-González M.Á.

Corella D.

Salas-Salvadó J.

Ruiz-Gutiérrez V.

Covas M.I.

Fiol M.

Gómez-Gracia E.

López-Sabater M.C.

Vinyoles E.

et al.

PREDIMED Study Investigators Effects of a Mediterranean-style diet on cardiovascular risk factors: a randomized trial. Ann. Intern. Med. 145 : 1-11 View in Article Scopus (1157)

PubMed

Crossref

Google Scholar

Feldman J.L.

Baeza J.

Denu J.M. Activation of the protein deacetylase SIRT6 by long-chain fatty acids and widespread deacylation by mammalian sirtuins. J. Biol. Chem. 288 : 31350-31356 View in Article Scopus (316)

PubMed

Crossref

Google Scholar

Gallardo-Montejano V.I.

Saxena G.

Kusminski C.M.

Yang C.

McAfee J.L.

Hahner L.

Hoch K.

Dubinsky W.

Narkar V.A.

Bickel P.E. Nuclear Perilipin 5 integrates lipid droplet lipolysis with PGC-1α/SIRT1-dependent transcriptional regulation of mitochondrial function. Nat. Commun. 7 : 12723 View in Article Scopus (40)

PubMed

Crossref

Google Scholar

Gemmink A.

Bosma M.

Kuijpers H.J.H.

Hoeks J.

Schaart G.

van Zandvoort M.A.M.J.

Schrauwen P.

Hesselink M.K.C. Decoration of intramyocellular lipid droplets with PLIN5 modulates fasting-induced insulin resistance and lipotoxicity in humans. Diabetologia. 59 : 1040-1048 View in Article Scopus (22)

PubMed

Crossref

Google Scholar

Granneman J.G.

Moore H.P.H.

Krishnamoorthy R.

Rathod M. Perilipin controls lipolysis by regulating the interactions of AB-hydrolase containing 5 (Abhd5) and adipose triglyceride lipase (Atgl). J. Biol. Chem. 284 : 34538-34544 View in Article Scopus (208)

PubMed

Crossref

Google Scholar

Greenberg A.S.

Coleman R.A.

Kraemer F.B.

McManaman J.L.

Obin M.S.

Puri V.

Yan Q.W.

Miyoshi H.

Mashek D.G. The role of lipid droplets in metabolic disease in rodents and humans. J. Clin. Invest. 121 : 2102-2110 View in Article Scopus (352)

PubMed

Crossref

Google Scholar

Haemmerle G.

Moustafa T.

Woelkart G.

Büttner S.

Schmidt A.

van de Weijer T.

Hesselink M.

Jaeger D.

Kienesberger P.C.

Zierler K.

et al. ATGL-mediated fat catabolism regulates cardiac mitochondrial function via PPAR-α and PGC-1. Nat. Med. 17 : 1076-1085 View in Article Scopus (382)

PubMed

Crossref

Google Scholar

Hubbard B.P.

Gomes A.P.

Dai H.

Li J.

Case A.W.

Considine T.

Riera T.V.

Lee J.E.

e S.Y.

Lamming D.W.

et al. Evidence for a common mechanism of SIRT1 regulation by allosteric activators. Science. 339 : 1216-1219 View in Article Scopus (384)

PubMed

Crossref

Google Scholar

Kim D.

Nguyen M.D.

Dobbin M.M.

Fischer A.

Sananbenesi F.

Rodgers J.T.

Delalle I.

Baur J.A.

Sui G.

Armour S.M.

et al. SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer’s disease and amyotrophic lateral sclerosis. EMBO J. 26 : 3169-3179 View in Article Scopus (770)

PubMed

Crossref

Google Scholar

Kuramoto K.

Okamura T.

Yamaguchi T.

Nakamura T.Y.

Wakabayashi S.

Morinaga H.

Nomura M.

Yanase T.

Otsu K.

Usuda N.

et al. Perilipin 5, a lipid droplet-binding protein, protects heart from oxidative burden by sequestering fatty acid from excessive oxidation. J. Biol. Chem. 287 : 23852-23863 View in Article Scopus (128)

PubMed

Crossref

Google Scholar

Lim J.-H.

Gerhart-Hines Z.

Dominy J.E.

Lee Y.

Kim S.

Tabata M.

Xiang Y.K.

Puigserver P. Oleic acid stimulates complete oxidation of fatty acids through protein kinase A-dependent activation of SIRT1-PGC1α complex. J. Biol. Chem. 288 : 7117-7126 View in Article Scopus (86)

PubMed

Crossref

Google Scholar

Mason R.R.

Mokhtar R.

Matzaris M.

Selathurai A.

Kowalski G.M.

Mokbel N.

Meikle P.J.

Bruce C.R.

Watt M.J. PLIN5 deletion remodels intracellular lipid composition and causes insulin resistance in muscle. Mol. Metab. 3 : 652-663 View in Article Scopus (63)

PubMed

Crossref

Google Scholar

McIntosh A.L.

Senthivinayagam S.

Moon K.C.

Gupta S.

Lwande J.S.

Murphy C.C.

Storey S.M.

Atshaves B.P. Direct interaction of Plin2 with lipids on the surface of lipid droplets: a live cell FRET analysis. Am. J. Physiol. Cell Physiol. 303 : C728-C742 View in Article Scopus (34)

PubMed

Crossref

Google Scholar

Miyoshi H.

Perfield 2nd, J.W.

Souza S.C.

Shen W.J.

Zhang H.H.

Stancheva Z.S.

Kraemer F.B.

Obin M.S.

Greenberg A.S. Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytes. J. Biol. Chem. 282 : 996-1002 View in Article Scopus (207)

PubMed

Crossref

Google Scholar

Mohktar R.A.M.

Montgomery M.K.

Murphy R.M.

Watt M.J. Perilipin 5 is dispensable for normal substrate metabolism and in the adaptation of skeletal muscle to exercise training. Am. J. Physiol. Endocrinol. Metab. 311 : E128-E137 View in Article Scopus (5)

PubMed

Crossref

Google Scholar

Muratore K.A.

Najt C.P.

Livezey N.M.

Marti J.

Mashek D.G.

Arriaga E.A. Sizing lipid droplets from adult and geriatric mouse liver tissue via nanoparticle tracking analysis. Anal. Bioanal. Chem. 410 : 3629-3638 View in Article Scopus (2)

PubMed

Crossref

Google Scholar

Najt C.P.

Senthivinayagam S.

Aljazi M.B.

Fader K.A.

Olenic S.D.

Brock J.R.

Lydic T.A.

Jones A.D.

Atshaves B.P. Liver-specific loss of Perilipin 2 alleviates diet-induced hepatic steatosis, inflammation, and fibrosis. Am. J. Physiol. Gastrointest. Liver Physiol. 310 : G726-G738 View in Article Scopus (30)

PubMed

Crossref

Google Scholar

Nogueira L.M.

Lavigne J.A.

Chandramouli G.V.R.

Lui H.

Barrett J.C.

Hursting S.D. Dose-dependent effects of calorie restriction on gene expression, metabolism, and tumor progression are partially mediated by insulin-like growth factor-1. Cancer Med. 1 : 275-288 View in Article Scopus (29)

PubMed

Crossref

Google Scholar

Ong K.T.

Mashek M.T.

Bu S.Y.

Greenberg A.S.

Mashek D.G. Adipose triglyceride lipase is a major hepatic lipase that regulates triacylglycerol turnover and fatty acid signaling and partitioning. Hepatology. 53 : 116-126 View in Article Scopus (187)

PubMed

Crossref

Google Scholar

Peng L.

Yuan Z.

Ling H.

Fukasawa K.

Robertson K.

Olashaw N.

Koomen J.

Chen J.

Lane W.S.

Seto E. SIRT1 deacetylates the DNA methyltransferase 1 (DNMT1) protein and alters its activities. Mol. Cell. Biol. 31 : 4720-4734 View in Article Scopus (110)

PubMed

Crossref

Google Scholar

Perez M.

Blankenhorn J.

Murray K.J.

Parker L.L. High-throughput identification of FLT3 wild-type and mutant kinase substrate preferences and application to design of sensitive in vitro kinase assay substrates. Mol. Cell. Proteomics. 18 : 477-489 View in Article Scopus (2)

PubMed

Crossref

Google Scholar

Pollak N.M.

Jaeger D.

Kolleritsch S.

Zimmermann R.

Zechner R.

Lass A.

Haemmerle G. The interplay of protein kinase A and perilipin 5 regulates cardiac lipolysis. J. Biol. Chem. 290 : 1295-1306 View in Article Scopus (39)

PubMed

Crossref

Google Scholar

Rodríguez V.M.

Portillo M.P.

Picó C.

Macarulla M.T.

Palou A. Olive oil feeding up-regulates uncoupling protein genes in rat brown adipose tissue and skeletal muscle. Am. J. Clin. Nutr. 75 : 213-220 View in Article Scopus (82)

PubMed

Crossref

Google Scholar

Salas-Salvadó J.

Bulló M.

Babio N.

Martínez-González M.Á.

Ibarrola-Jurado N.

Basora J.

Estruch R.

Covas M.I.

Corella D.

Arós F.

et al.

PREDIMED Study Investigators Reduction in the incidence of type 2 diabetes with the Mediterranean diet: results of the PREDIMED-Reus nutrition intervention randomized trial. Diabetes Care. 34 : 14-19 View in Article Scopus (453)

PubMed

Crossref

Google Scholar

Schwingshackl L.

Hoffmann G. Monounsaturated fatty acids, olive oil and health status: a systematic review and meta-analysis of cohort studies. Lipids Health Dis. 13 : 154 View in Article Scopus (171)

PubMed

Crossref

Google Scholar

Schwingshackl L.

Strasser B.

Hoffmann G. Effects of monounsaturated fatty acids on glycaemic control in patients with abnormal glucose metabolism: a systematic review and meta-analysis. Ann. Nutr. Metab. 58 : 290-296 View in Article Scopus (74)

PubMed

Crossref

Google Scholar

Shepherd S.O.

Cocks M.

Tipton K.D.

Ranasinghe A.M.

Barker T.A.

Burniston J.G.

Wagenmakers A.J.M.

Shaw C.S. Sprint interval and traditional endurance training increase net intramuscular triglyceride breakdown and expression of perilipin 2 and 5. J. Physiol. 591 : 657-675 View in Article Scopus (105)

PubMed

Crossref

Google Scholar

Shin S.

Ajuwon K.M. Effects of Diets Differing in Composition of 18-C Fatty Acids on Adipose Tissue Thermogenic Gene Expression in Mice Fed High-Fat Diets. Nutrients. 10 : E256 View in Article Scopus (10)

PubMed

Crossref

Google Scholar

Sofi F.

Abbate R.

Gensini G.F.

Casini A. Accruing evidence on benefits of adherence to the Mediterranean diet on health: an updated systematic review and meta-analysis. Am. J. Clin. Nutr. 92 : 1189-1196 View in Article Scopus (954)

PubMed

Crossref

Google Scholar

Sreerama N.

Woody R.W. Estimation of protein secondary structure from circular dichroism spectra: comparison of CONTIN, SELCON, and CDSSTR methods with an expanded reference set. Anal. Biochem. 287 : 252-260 View in Article Scopus (2181)

PubMed

Crossref

Google Scholar

Storey S.M.

McIntosh A.L.

Huang H.

Landrock K.K.

Martin G.G.

Landrock D.

Payne H.R.

Atshaves B.P.

Kier A.B.

Schroeder F. Intracellular cholesterol-binding proteins enhance HDL-mediated cholesterol uptake in cultured primary mouse hepatocytes. Am. J. Physiol. Gastrointest. Liver Physiol. 302 : G824-G839 View in Article Scopus (26)

PubMed

Crossref

Google Scholar

Sztalryd C.

Brasaemle D.L. The perilipin family of lipid droplet proteins: Gatekeepers of intracellular lipolysis. Biochim Biophys Acta Mol Cell Biol Lipids. 1862 : 1221-1232 View in Article Scopus (83)

PubMed

Crossref

Google Scholar

Trichopoulou A.

Orfanos P.

Norat T.

Bueno-de-Mesquita B.

Ocké M.C.

Peeters P.H.

van der Schouw Y.T.

Boeing H.

Hoffmann K.

Boffetta P.

et al. Modified Mediterranean diet and survival: EPIC-elderly prospective cohort study. BMJ. 330 : 991 View in Article Scopus (499)

PubMed

Crossref

Google Scholar

Wang C.

Zhao Y.

Gao X.

Li L.

Yuan Y.

Liu F.

Zhang L.

Wu J.

Hu P.

Zhang X.

et al. Perilipin 5 improves hepatic lipotoxicity by inhibiting lipolysis. Hepatology. 61 : 870-882 View in Article Scopus (88)

PubMed

Crossref

Google Scholar