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Germany's World Cup preparations have been rocked after Marco Reus was ruled out of the tournament in Brazil, kicking off in five days time.

The Borussia Dortmund star, 25, sustained ankle ligament damage during his country's 6-1 win over Armenia in Mainz on Friday evening, following a tussle with opposing midfielder Artur Yedigaryan.

Reus had to be helped from the field just minutes before half-time, unable to put any weight on his injured leg as he left the field.

And now the German FA have confirmed that Reus, who scored 23 goals in 43 games for Dortmund during the 2013-14 campaign, will miss out on the finals, after suffering a tear of the syndemosis joint in his ankle.

“He suffered a partial tear of his anterior ligament above his left ankle,” said a statement from Die Mannschaft.

Sampdoria's 22-year-old defender Shkodran Mustafi, who spent two years with Everton earlier in his career, has been called up as Reus' replacement in Joachim Low's 23-man squad.

Germany meet Portugal, Ghana and the United States in Brazil.

Take a look at our World Cup guide on the three time World Cup winners.