After 150 years in the same hands, the landmark Soul Pattinson heritage building in Pitt Street Mall is to be sold with a value of more than $100 million.

It is the fourth-last privately owned property along the strip, which houses one of the longest-running chemists in the country. No decision has been made regarding the chemist business, but any new owner is expected to review the property, tenant and the air rights for redevelopment, including heritage issues.

The Washington H. Soul Pattinson building at 160 Pitt Street Mall is on the market. Credit:Robert Tuckwell

The Washington H. Soul Pattinson business was founded in 1870, the chemist was opened in 1873 and has seen Pitt Street Mall evolve into one of the busiest shopping strips per capita in the world.

It is now home to some of the richest retailers in the world including the owners of fast fashion labels Zara, H&M, Forever 21 and Westfield Sydney, now owned by the Scentre Group. But most of the properties are predominantly owned by real estate investment trusts, including Stockland and Investa.