Marcia Adelman on March 8, 2017 at 4:54 pm



Thank you Cort for this excellent write-up on the video talk. Dr. Davis mentioned the use of mTOR Inhibitors in this latest video. I listened a few times to this section but could not discern if he was cautioning against the use of mTOR Inhibitors for ALL ME/CFS patients or just a subset that may have mTOR gene mutations. He said – “You don’t want to take something that inhibits mTOR…” I am surprised and dismayed about this statement and really would like additional clarification…because I just started taking Rapamune (Sirolimus) which is an mTOR inhibitor, about a month ago and have experienced SIGNIFICANT improvement in both physical and cognitive functionality. Nothing else changed in my regimen during this time.



The oncologist/hematologist who prescribed this drug has 4 other patients that are taking Rapamune and all have experienced the same improvement that I have. I don’t know if it will last but besides LDN, it is the only thing that has moved the needle for me. Anti-virals did nothing for me. I posted about about Rapamune in another thread (the guy with the Castleman’s disease) but want to keep with this thread because of Dr. Davis mention. Anything you or others can add would be appreciated. Or is there an email I can contact Ron or Linda Tannenbaum directly for clarification? Thanks