A charter bus full of Louisiana flood volunteers slammed into a fire truck Sunday morning in a terrifying crash that left 41 people injured and two left dead.

The crash happened near Laplace when the seemingly out-of-control bus raced down the Interstate 10, striking a parked fire engine that was attending to a previous crash and knocking three firefighters over a guardrail, killing one.

The driver, Denis Yasmir Amaya Rodriguez, was in the country illegally and was not licensed to be behind the wheel, police told NY Daily News.

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Tragic: A charter bus full of Louisiana flood volunteers slammed into a fire truck Sunday morning in a terrifying crash that left 41 people injured and two left dead

The crash happened near Laplace when the seemingly out-of-control bus raced down the Interstate 10, striking a parked fire engine that was attending to a previous crash and knocking three firefighters over a guardrail, killing one

Help: A bus full of volunteers heading to flooded Baton Rouge crashed into a parked fire truck causing a massive smash (pictured) on the Interstate 10 on Sunday

Smash: The smash killed two: a fire chief and a car driver. The bus's driver, Denis Rodriguez, survived but was discovered by police to be both unlicensed and an illegal immigrant

Denis Yasmir Amaya Rodriguez, identified by police as the driver of a private rental bus involved in a multiple car accident which killed two people, is seen in a picture released by the Louisiana State Police

St John the Baptist Parish Office of Fire Services had arrived on the scene earlier Sunday to deal with a crashed truck, blocking the left-hand lane with a fire truck.

But an already difficult day turned tragic when the charter bus - which was full of volunteers hoping to help with flooding in Baton Rouge - raced down that left-hand lane and into the stationary fire truck.

It then swerved across the roadway, knocking three firefighters over a guard rail and into the waters below - one of whom died. That victim has not been named.

The bus then smashed into at least one other vehicle, killing the driver of that car.

Police identified the slain fire fighter as Spencer Chauvin, district fire chief of the St John fire services.

'It is a sad day in St John the Baptist Parish as we lost one of the bravest and most dedicated firefighters that I know,' parish president Natalie Robottom said in a statement.

'This was a horrific accident and one that is still very active. This type of loss will affect the entire department and they will have our full support as they deal with the grief of losing a comrade.'

Everyone in the chartered bus was injured.

Criminal charges are pending while police figure out who owns the bus.