WASHINGTON, DC - JANUARY 31: Secretary of State Hillary Clinton delivers her final speech as Secretary of State, at the Council on Foreign Relations, on January 31, 2013 in Washington, DC. Friday February 1st will be Secretary Clintons last day before being replaced by Sen. John Kerry (D-MD) who this week was confirmed by the U.S. Senate. (Photo by Mark Wilson/Getty Images) Secretary of State Hillary Clinton delivers her final speech as Secretary of State, at the Council on Foreign Relations, on Jan. 31, 2013 in Washington, D.C. (credit: Mark Wilson/Getty Images)

WASHINGTON — Secretary of State Hillary Rodham Clinton is leaving office with a slap at critics of the Obama administration’s handling of the September attack on a U.S. diplomatic mission in Libya. She told The Associated Press that critics of the administration’s handling of the attack don’t live in an “evidence-based world” and their refusal to “accept the facts” is unfortunate and regrettable for the political system.

In her last one-on-one interview before she steps down on Friday, Clinton told the AP that the attack in Benghazi was the low point of her time as America’s top diplomat. But she suggested that the furor over the assault would not affect whether she runs for president in 2016.

Although she insisted that she has not decided what her future holds, she said she “absolutely” still plans to make a difference on issues she cares about in speeches and in a sequel to her 2003 memoir, “Living History,” that will focus largely on her years as secretary of state.

Clinton spoke to the AP Thursday in her outer office on the seventh floor of the State Department less than 24 hours before she walks out for a final time as boss. She was relaxed but clearly perturbed by allegations from Republican lawmakers and commentators that the administration had intentionally misled the public about whether the attack was a protest gone awry or a terrorist attack, or intentionally withheld additional security for diplomatic personnel in Libya knowing that an attack could happen.

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An independent panel she convened to look into the incident was scathing in its criticism of the State Department and singled out four officials for serious management and leadership failures. But it also determined that there was no guarantee that extra personnel could have prevented the deaths of the U.S. ambassador to Libya, Chris Stevens, and three other Americans. Clinton herself was not blamed, although she has said she accepted responsibility for the situation.

“I was so unhappy with the way that some people refused to accept the facts, refused to accept the findings of an independent Accountability Review Board, politicized everything about this terrible attack,” she said. “My job is to admit that we have to make improvements and we’re going to.”

Clinton faced a barrage of hostile questions about Benghazi from Republican lawmakers when she testified before Congress recently in appearances that were delayed from December because of illness. Afterward, some lawmakers continued to accuse her and the administration of withholding evidence. Sen. Lindsay Graham, R-S.C., told a television interviewer that he thought Clinton was getting “away with murder.”

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In the interview, Clinton had little patience for such allegations.

“There are some people in politics and in the press who can’t be confused by the facts,” she said. “They just will not live in an evidence-based world. And that’s regrettable. It’s regrettable for our political system and for the people who serve our government in very dangerous, difficult circumstances.”

At the same time, Clinton said she refused to be “discouraged by the fact that they are never going to accept the facts and the limitations of the facts.” She added that “you have to get up every day and work to do best you can and communicate that to the vast majority of fair-minded Americans whether they’re in Congress, in the press or in the public.”

Because of that, she said, the partisan divide should not dissuade anyone with a cause from getting involved in politics and she hinted strongly that a divisive atmosphere would not stop her in any future endeavor. “You have to have a thick skin because (politics) is just going to be a contact sport as far as we can look into the future.”

Clinton is no stranger to partisan politics. As first lady, she railed in 1998 against a “vast right-wing conspiracy” that she asserted had been attacking her husband, Bill Clinton, ever since he had become president.

But the woman who was once considered a divisive figure in American politics, yet leaves office as one of its most popular, remained coy about whether she would run for president in 2016.

“I am making no decisions, but I would never give that advice to someone that I wouldn’t take myself,” she said. “If you believe you can make a difference, not just in politics, in public service, in advocacy around all these important issues, then you have to be prepared to accept that you are not going to get 100 percent approval.”

Asked if she still thought she could make a difference, Clinton replied, “Absolutely,” but added quickly that she hadn’t yet decided how.

“I have deliberately cabined it off,” she said. “I am going to be secretary of state until the very last minute when I walk out the door. And then I am going to take the weekend off and then I may start thinking about all the various offers and requests and ideas that have come my way.

“I have made no decisions and I just can’t until I have time to think it through and see how I am going to put it all together. I will certainly write something. I will certainly speak. Those are givens, but the rest of it I don’t have in mind. And I hope through my writing and speaking to continue making a difference as well.”

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