''An Isolated Complex V Inefficiency and Dysregulated Mitochondrial Function in Immortalized Lymphocytes from ME/CFS Patients'' by Missailidis et al.

Immortalized lymphoblasts from 51 ME patients and a matched control group were studied using several methods including Seahorse.

The results suggest a model in which a Complex V defect in mitochondria is compensated by upregulation of other processes which enables normal ATP synthesis in resting cells, but leaves them unable to respond adequately to increases in energy demand.

Paper

here

Thread

here



27 females with confirmed CFS filled in physical functioning and fatigue questionnaires and did 2 physical tests: ‘Timed Loaded Standing’ (TLS), assessing trunk-arm endurance, and the ‘Stops Walking with Eyes Closed while performing a secondary Cognitive Task’ (SWECCT), measuring impaired automaticity of gait.

TLS correlated significantly with SF-36 physical functioning. None of the other associations was significant. The authors suggest TLS may be a useful monitoring tool for CFS.

Paper ''Assessing CFS: Self-reported physical functioning and correlations with physical testing'' by Eyskens et al.27 females with confirmed CFS filled in physical functioning and fatigue questionnaires and did 2 physical tests: ‘Timed Loaded Standing’ (TLS), assessing trunk-arm endurance, and the ‘Stops Walking with Eyes Closed while performing a secondary Cognitive Task’ (SWECCT), measuring impaired automaticity of gait.TLS correlated significantly with SF-36 physical functioning. None of the other associations was significant. The authors suggest TLS may be a useful monitoring tool for CFS.Paper here Thread here



Article



Tripathi et al. (2019). Modern-Day Relics of Psychiatry.

Article



Murga & Lafuente (2019). From neurasthenia to post-exertion disease: Evolution of the diagnostic criteria of chronic fatigue syndrome/myalgic encephalomyelitis.

Article

​ Overholser et al. (2019). Neurasthenia Modern Malady or Historical Relic?Article here Thread here Tripathi et al. (2019). Modern-Day Relics of Psychiatry.Article here Thread here Murga & Lafuente (2019). From neurasthenia to post-exertion disease: Evolution of the diagnostic criteria of chronic fatigue syndrome/myalgic encephalomyelitis.Article here Thread here



Details Detecting Mycotoxin Subgroup'' involving questionnaires and blood draw.Details here Thread here