A 28-year-old woman has been reported missing from a hotel in Sydney.

Kimberley Poulson was last seen outside the Earlwood Hotel on Homer St, Earlwood, about 7.30am (AEDT) on Friday, police said.

Ms Poulson's family became concerned when she failed to return to the pub, where she had been living, and could not be contacted on her phone.

Police said they were concerned about her welfare as she has an intellectual disability.

She is described as being of Caucasian appearance, about 130cm to 140cm tall, of solid build and blonde.

Anyone with information should contact Ashfield Police or Crime Stoppers on 1800 333 000.

Originally published as Woman, 28, reported missing from pub