Donald Trump Donald John TrumpBiden leads Trump by 36 points nationally among Latinos: poll Trump dismisses climate change role in fires, says Newsom needs to manage forest better Jimmy Kimmel hits Trump for rallies while hosting Emmy Awards MORE slammed MSNBC host Joe Scarborough as "sad and irrelevant" Wednesday after Scarborough called on Republican leaders to remove Trump as the party's presidential nominee.

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"Morning Joe's weakness is its low ratings. I don't watch anymore but I heard he went wild against Rudy Giuliani and #2A - sad & irrelevant!" Trump tweeted, referring to the Second Amendment in shorthand.

Morning Joe's weakness is its low ratings. I don't watch anymore but I heard he went wild against Rudy Giuliani and #2A - sad & irrelevant! — Donald J. Trump (@realDonaldTrump) August 10, 2016

Scarborough, a former Republican congressman, has been a consistent critic of Trump throughout his presidential campaign.

He quickly responded to Trump's tweet: "Donald thanks for continuing to obsess over our irrelevant show that you watch everyday. Highest ratings ever. Glad!"

Donald thanks for continuing to obsess over our irrelevant show that you watch everyday. Highest ratings ever. Glad! https://t.co/nff7rD9C2y — Joe Scarborough (@JoeNBC) August 10, 2016

On Wednesday, Scarborough called on Speaker Paul Ryan Paul Davis RyanKenosha will be a good bellwether in 2020 At indoor rally, Pence says election runs through Wisconsin Juan Williams: Breaking down the debates MORE (R-Wis.) and Republican leadership to denounce Trump following remarks — which many interpreted as a joke, but which others saw as threatening — about the possibility of "Second Amendment folks" taking action against Democratic presidential nominee Hillary Clinton Hillary Diane Rodham ClintonBiden leads Trump by 36 points nationally among Latinos: poll Democratic super PAC to hit Trump in battleground states over coronavirus deaths Battle lines drawn on precedent in Supreme Court fight MORE.

"A bloody line has been crossed that cannot be ignored. At long last, Donald Trump has left the Republican Party few options but to act decisively and get this political train wreck off the tracks before something terrible happens," Scarborough wrote in an op-ed in The Washington Post.

And on his show, Scarborough accused leaders of letting Trump destroy the Republican Party.

"We've said from the very beginning, when he started blowing himself up, when Paul Ryan endorsed him, that it's only going to get worse. And it just keeps getting worse, doesn't it?” he said.