It's over for Helena Bonham Carter and Tim Burton.

E! News confirms the two have called it quits after 13 years together. The pair, who never married, have two children together, son Billy, 11, and daughter Nell, 7.

"Tim Burton and Helena Bonham Carter separated amicably earlier this year and have continued to be friends and co-parent their children," reps for both Burton and Carter tell E! News. "We would ask that you respect their privacy and that of their children during this time."

The 56-year-old director and the 48-year-old actress met in 2001 while filming Planet of the Apes, which Burton directed.