The missiles destroyed heavy equipment and killed fighters that Islamic State had transferred from its stronghold, Raqqa, to Palmyra, the Russian Defense Ministry has said.

READ MORE: Video of Russian Navy firing cruise missiles on ISIS positions near Palmyra

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The Russian warships, a frigate named Admiral Essen and submarine named Krasnodar, fired Kalibr cruise missiles on combat vehicles and militants outside the Syrian city of Palmyra, the Defense Ministry said.

The four cruise missiles were fired from the eastern Mediterranean, it noted in a statement. The submarine fired its missiles while submerged.

According to the MoD, “[the ships] targeted an area east of Palmyra, where the militants’ heavy weaponry and manpower were located. The militants moved there from Raqqa. All targets have been destroyed,” it said.

The US, Turkish, and Israeli militaries received appropriate warning in advance of the missile launches through active hotlines, the Defense Ministry added.

On May 25, a large Islamic State convoy, comprising 39 vehicles and 120 militants, was spotted outside Raqqa, a Defense Ministry source told RIA Novosti on Saturday.

“The terrorist convoy of 39 pickup trucks was detected and destroyed by the Air Force on its way to Palmyra,” the source said, adding that the vehicles were equipped with large-caliber machine guns.



READ MORE: Russian Black Sea Fleet carries out missile strikes on terrorist targets in Syria - military

The Russian Navy also fired Kalibr cruise missiles on militant positions in Syria last year. The Black Sea Fleet carried out three cruise missile strikes on terrorist targets in Syria back in August, destroying a command post and munitions production site. The missiles, which targeted Al-Nusra Front positions, flew over unpopulated areas, the Russian military said.

In October of 2015, four Russian Navy warships fired a total of 26 missiles from the Caspian Sea at positions Islamic State in Syria. The precision weapons hit all 11 targets after flying some 1,500 kilometers, according to the military. Preparation for the launches involved communications with Iran and Iraq, as the missiles had to pass their through the airspace of those countries to reach Syria.

The Defense Ministry said it had worked with its partners in plotting the flight path to assure that the missiles traveled only over desolate areas and posed no danger to civilians.