A 40-year-old Greenslopes man has died after a truck struck an overpass and rolled in Brisbane's inner south this morning.

Police said the tragic accident was a case of being in the "wrong place at the wrong time."

The man was crushed after the truck clipped a rail bridge on Annerley Rd at Dutton Park and overturned.

The accident occurred about 7.30am, initially interrupting trains and causing road closures.

Forensics crash officers are investigating but police say it's too early to say whether charges will be laid.

Trucks get stuck at rate of one a week