The Hotel Hassler offers a Signature Treatment at its spa that includes a wine body scrub and a massage with vinacciolo, oil made from the seeds of wine-producing grapes. This anti-aging treatment combines the virtues of wine with those of natural grape seed extracts, said to strengthen the blood vessels and enhance microcirculation.

During the Carmenère Wine Bath at this upscale hotel, guests sink into a hot mixture of Carmenère, mineral water and oats that not only soothes your senses, but also provides exfoliation and hydration. Price varies, but the hotel’s “Bath Butler” is available to assist with any request.

Located in Manhattan’s tony Plaza Hotel, a visit to this spa is like a quick escape to French wine country. Indulge in a massage, where finely crushed grapes (seed, skin, stalk and pulp) exfoliate dry skin. Follow that with a Wine Barrel Bath (a jacuzzi resembling a giant wine barrel) filled with spring water and enriched with grape seed essential oils, thought to fight free radicals.

Located a stone’s throw from the Great Barrier Reef, Spa Qualia (founded by Australian winemaker Bob Oatley) offers couples a Wine Lovers treatment that includes a Chardonnay massage, detoxifying Pinot Noir body mask and a Burgundy bath (along with Champagne service). Guests take away a bottle of Pinot Noir or Chardonnay.

Wine therapies are the treatment of choice at this small 29-room luxury inn. Vinotherapy and grape-based spa treatments using resources from nearby vineyards include the Kenwood Wine Wrap, a signature treatment that features the application of clays, red wine extract and essential oils. After a wrap and dry brush, you’ll be moisturized with the Inn’s signature grape seed lotion that includes Chardonnay and Riesling oils as well as red wine extract.

Ampelo-terapia, or grape therapy, is a unique treatment utilizing all of the anti-oxidant properties of grapes. The 80-minute Grapes Experience includes a detoxifying bath, an exfoliating body scrub, a grape-based wrap scented with sandalwood and myrrh and a body brush of red wine.