One half of reality television's greatest Beauty and the Beast story has come to an end. MTV personality Diem Brown passed away Friday morning in New York City, following her third battle with cancer, People confirmed. She was 32.

On Tuesday, Brown tweeted for the last time still filled with hope, but admitting her condition was looking increasingly dire. "I NEED PRAyErs and advice my doctors are seemingly giving up but I won't & can't rollover. Whatever option I have to LIVE I'm grabbing!" Later, she added, "No is not an option."

Brown rose to fame in 2005 when she appeared on MTV's Real World/Road Rules Challenge. She quickly became a fan favorite thanks in part to her positive attitude and willingness to be open about her health. While filming the reality show, Brown told her castmates that she was fighting ovarian cancer, something not even the crew was aware of when the show began.

The removal of her blond wig for the first time was an unforgettable moment for the series and the network, and her years-long relationship with tough guy Chris "CT" Tumburello among its most shipped unions.

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The disease returned in 2012, after Brown had appeared on numerous other television shows. Speaking to Dr. Drew Pinsky, she said that she was completely shocked when the cancer returned. "I didn't understand, really, that it could come back again," she said. "Finding out you have it a second time, it's like, 'I've already done this, I thought I was over it.'"

A year later, the cancer again went into remission. However, in August 2014, Brown announced that she'd been diagnosed with colon cancer. In September, she told E! Online that she is "really looking forward to having one painless, fun day" sometime down the road.

Many of Diem's friends, famous and otherwise, stood loyal by her side through the end, including CT, although they hadn't been together in years. Tumberello posted a picture of the pair holding hands at the hospital several months before her death. One week before her death, he shared on Instagram, "Your smile can change the world. It's not the other way around."

Brown was public about her illnesses, chronicling her struggles with online journals and videos. In one video, Brown showed what it was like to lose her hair while undergoing chemotherapy. She also created MedGift, a patient gift registry to help patients gather financial support for their medical needs from friends and family.

In a 2012 blog for People, Brown wrote about her desire to be a mother in the future and the guilt she sometimes experienced over her decision to continue fertility treatments while fighting ovarian cancer.

"I don't want to be judged for my decisions, although I know that I will," she wrote of her choice to have her eggs harvested before her ovaries were removed. "I don't want to feel guilty for my decisions, although I know that I will. Some people think that I am not taking my health seriously and risking too much if I choose to follow through with this next round of hormone/fertility treatments and delay my ovary removal surgery and subsequent chemo treatments. I understand and appreciate those concerns."

"Cancer has changed who I am," Brown told People magazine. "It sounds like a cliché, but I've only got this one life, and I need to live every day to the fullest."