Two teenagers have been charged with attempted murder after a 16-year-old girl with several stab wounds was found inside a burning house.

Key points: Police charge two boys, aged 16 and 17, after a girl is found with stab wounds inside a burning house

Police charge two boys, aged 16 and 17, after a girl is found with stab wounds inside a burning house The 16-year-old victim remains in a serious but stable condition in hospital

The 16-year-old victim remains in a serious but stable condition in hospital The accused teenagers have appeared in court and were remanded to appear at a later date

Fire crews were called to an Albury property in southern NSW on Monday morning and discovered the semi-conscious teenager with wounds to her abdomen, back and head.

Murray River Police District Acting Inspector Troy Martin said she was lucky to be alive and praised firefighters for their efforts.

"It was amazing work, given the conditions they were faced with when they arrived at the scene," he said.

"What they did and being able to find that young person in a house that contained a lot of smoke and fire, the firies did an amazing job."

The girl was taken to Albury Base Hospital with a punctured liver and suffering smoke inhalation. She remains in a serious but stable condition.

Teenagers to face court

It is alleged she was assaulted by two males, aged 16 and 17, before a bedroom in the home was set on fire.

"It's very concerning that two young persons are involved in these types of matters," Inspector Martin said.

Police say the incident started to unfold just after midnight Sunday when the boys went to the home and asked to stay the night.

It is understood the two accused boys and the girl are known to each other.

Inspector Martin said he was not able to comment if adults were home at the time, but said police were treating it as an isolated incident.

"People don't need to have any fears or concerns; this is definitely an isolated incident," he said.

Both teenagers faced the Children's Court in Albury on Tuesday and were remanded in custody to appear at a later date.

House severely damaged

The house was engulfed in flames when fire crews arrived at the scene.

NSW Fire and Rescue Superintendent Stewart Alexander said it took five tankers and more than 20 firefighters over an hour to bring the blaze under control.

"The house has sustained severe damage and we do have concerns about a roof collapse," he said.

"Both adjoining neighbours have suffered some smoke damage, however they are OK, they haven't suffered any fire damage."