“Physically we are in good shape, so I’m not worried about it,” de Boer said.

In addition to not playing Parkhurst and Nagbe against Vancouver, de Boer chose not to start centerback Miles Robinson and midfielder Julian Gressel. Both came on as subs.

Among the players who aren’t healthy are midfielder Brandon Vazquez and fullback George Bello.

De Boer said when he was a player, he liked playing every 3-4 days. He said travel while playing in MLS is more difficult than while playing in Europe, though. Parkhurst said he took a nap on his day off Wednesday.

“If we prepare them well and they do what we tell them with rest and good nutrition, you can deal with it,” de Boer said.