MSNBC anchor Chris Matthews said on Wednesday that "to upset the American people's will" by impeaching President Donald Trump would be "an awesome task."

"To upset the American people's will is an awesome task," Matthews said.

"You and I know how hard it is to overtake the will of the American people in the Electoral College," Matthews said. "With all the arguments about the Electoral College, that's how we pick our presidents. To overturn a decision like that is a humongous lift. It requires evidence, it requires politics, it requires political power."

Special counsel Robert Mueller gave a press conference on Wednesday morning where he reiterated the findings of his report.

"We concluded that we would not reach a determination one way or the other about whether the president committed a crime. That is the office's final position and we will not comment on any other conclusions or hypotheticals about the president," Mueller said. "The report is my testimony. I would not provide information beyond that which is already public in any appearance before Congress."

After Mueller's press conference, the calls from Democratic presidential candidates to begin an impeachment inquiry intensified. Sen. Kamala Harris (D., Calif.) and Sen. Cory Booker (D., N.J.) sent tweets calling for Congress to begin the impeachment process while former vice president Joe Biden took a more cautious approach.

Matthews added that it was unlikely Trump would be removed from office.

"Right now you have a weaponized Republican Senate right now, who will do anything this president wants. There are no people there that will linger, and say ‘Well, maybe I should use my conscience on this one.' There's nobody like that," Matthew said.