It is not pleasant to contemplate the thoughts that must be passing through the mind of the Owl of Minerva as the dusk falls and she undertakes the task of interpreting the era of human civilization, which may now be approaching its inglorious end.

The era opened almost 10,000 years ago in the Fertile Crescent, stretching from the lands of the Tigris and Euphrates, through Phoenicia on the eastern coast of the Mediterranean to the Nile Valley, and from there to Greece and beyond. What is happening in this region provides painful lessons on the depths to which the species can descend.

The land of the Tigris and Euphrates has been the scene of unspeakable horrors in recent years. The George W. Bush-Tony Blair aggression in 2003, which many Iraqis compared to the Mongol invasions of the 13th century, was yet another lethal blow. It destroyed much of what survived the Bill Clinton-driven UN sanctions on Iraq, condemned as "genocidal" by the distinguished diplomats Denis Halliday and Hans von Sponeck, who administered them before resigning in protest. Halliday and von Sponeck's devastating reports received the usual treatment accorded to unwanted facts.

One dreadful consequence of the US-UK invasion is depicted in a New York Times "visual guide to the crisis in Iraq and Syria": the radical change of Baghdad from mixed neighborhoods in 2003 to today's sectarian enclaves trapped in bitter hatred. The conflicts ignited by the invasion have spread beyond and are now tearing the entire region to shreds.

Much of the Tigris-Euphrates area is in the hands of ISIS and its self-proclaimed Islamic State, a grim caricature of the extremist form of radical Islam that has its home in Saudi Arabia. Patrick Cockburn, a Middle East correspondent for The Independent and one of the best-informed analysts of ISIS, describes it as "a very horrible, in many ways fascist organization, very sectarian, kills anybody who doesn't believe in their particular rigorous brand of Islam."

Cockburn also points out the contradiction in the Western reaction to the emergence of ISIS: efforts to stem its advance in Iraq along with others to undermine the group's major opponent in Syria, the brutal Bashar Assad regime. Meanwhile a major barrier to the spread of the ISIS plague to Lebanon is Hezbollah, a hated enemy of the US and its Israeli ally. And to complicate the situation further, the US and Iran now share a justified concern about the rise of the Islamic State, as do others in this highly conflicted region.

Egypt has plunged into some of its darkest days under a military dictatorship that continues to receive US support. Egypt's fate was not written in the stars. For centuries, alternative paths have been quite feasible, and not infrequently, a heavy imperial hand has barred the way.