8 Brainy Movies That (Almost) Get Neuroscientist Stamp of Approval CAS memory expert’s favorite mind-bending films, based on scientific accuracy

The accuracy of Hollywood’s depictions of memory erasure or manipulation varies wildly from film to film, but some movies actually do a pretty great job, says neuroscientist Steve Ramirez. The College of Arts & Sciences assistant professor of psychological and brain sciences is an expert on the human brain as well as an avid movie watcher. Whether or not you’ve seen Blade Runner 2049, released last fall, over the past few years you’ve likely consumed some fictionalized depiction of how memory works. It’s a hot topic, both in academic labs and in the film industry.

Inspired by a recent wave of movies on the subject, Ramirez ranked eight of his favorite “mind-bending” films in order of how realistic they are from a scientific perspective. Here’s his take on what Hollywood gets almost right and wrong:

1. Memento

Memento is one of the most realistic accounts of amnesia — the inability to form or recall our personally experienced events — that I’ve seen come out of Hollywood, because of its broken storyline. It has viewers piece the story together themselves.

2. Inside Out

Inside Out is a Pixar classic that zooms into a child’s brain and lets us see her memories form, change, and evaporate over time as she matures. It beautifully connects memories, our childhood, and how they are altered over time. Pixar nailed it: they actually consulted a team of neuroscientists for the movie to make sure they correctly depicted certain memories and emotions.

3. The Bourne Triology

The Bourne Trilogy (which starts with The Bourne Identity) is a fast-spaced action series about Jason Bourne, an agent with amnesia who knows how to win any fight, but doesn’t remember who he is or where he came from. Like Memento, it also does a good job highlighting how profound memory’s influence is on our identities and who we are at the core.

4. Inception

Inception is a mind-bending film on implanting and extracting memories in the brain, done with high-octane drama and a twisting, dream-like storyline. While we can’t enter people’s memories directly like in the movie, a rich body of literature does exist on the malleability of human memories and how easily false memories can be created.

5. Eternal Sunshine of the Spotless Mind

Eternal Sunshine of the Spotless Mind is perhaps the most famous memory erasure movie ever. Would you erase the memory of a loved one after a breakup if it eased the pain? We’ve been able to erase memories from mice brains, but memory erasure in humans is still far off on the horizon.

6. Blade Runner and Blade Runner 2049

Blade Runner and Blade Runner 2049 — a classic and instant-classic — tackle the concepts of implanting memories in human-like robots. It has one of the clearest depictions of just how much memories form the basis of our identities.

7. The Matrix

The Matrix is another classic. “I know Kung Fu,” says Neo, after having martial arts skills uploaded into his brain. The movie tackles the philosophical questions of brains, free will, uploading information onto the brain, and how this changes us forever.

8. Total Recall

Total Recall has the main character going into a machine where he can live out any reality or fantasy that he sees fit. Things get blurry, however, when reality and fantasy start to blend and force viewers to ask themselves: if our subjective reality feels real, then does it matter if it’s real or not?

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