A 15-year-old boy has died when the car he was driving, packed with teenage passengers, crashed into a tree at Sunshine West.

The boy was behind the wheel carrying four passengers along Oldfield Road when he lost control and struck a tree about 10pm.

The boy died at the scene, while the passengers were all taken to hospital.

A 17-year-old boy who was sitting in the front passenger seat, and a 16-year-old boy, who was in the backseat, both sustained serious injuries and were taken to the Royal Melbourne Hospital.