Billy Turner, who is listed as the backup right guard and right tackle on the Broncos' Week 11 depth chart, will start at left guard in Garcia's place.

"We've got guys in that room that [are] capable," Joseph said. "I thought leaving camp that we had the best line we've had here in a while as far as depth and as far as guys who can play guard, center and tackle. It happens, it's football. We've got Billy Turner playing the left guard, along with Eli [Wilkinson] playing the right guard, with [Connor McGovern] playing the center. So I'm comfortable. Let's go play."

Joseph said rookie Sam Jones and veteran Gino Gradkowski — who was signed earlier this week — will both be active on Sunday against the Chargers.

"That's why we signed Gino, because he's played a lot of football, especially at center," Joseph said. "That's a different deal than playing guard, so absolutely, that's why we signed Gino."

Garcia will likely join starting left guard Ron Leary and starting center Matt Paradis on injured reserve. Leary tore his Achilles in a Week 6 game against the Rams, while Paradis fractured his fibula and tore ligaments against the Texans in Week 9.

Starting right tackle Jared Veldheer has also missed significant time. He was held out of four games with a bone bruise before returning against the Texans.

Garcia's injury leaves the Broncos with eight healthy offensive linemen, and seven are expected to dress for Sunday's game against the Chargers.

"Ain't too many guys left," Joseph said, "so they're going to play."

Joseph also ruled out linebacker Brandon Marshall (knee) and safety Dymonte Thomas (ankle) for the Broncos' Week 11 game.

He did not confirm whether Marshall would return in Week 12 against the Steelers.

"He's progressing," Joseph said. "When he's healthy he'll play, but right now he's not. Josey [Jewell]'s played good football, and we'll see. We've got Su'a Cravens back, so he's playing some dime 'backer for us. But when he's healthy, he'll play."