There are many .......

Ibn al Xu'ffasch (Earth-22)

Ibn al Xu'ffasch is the adult illegitimate son of Batman and Talia al Ghul who is usually noted to have developed on alternate Earths. In most of these other alternate realities, Ibn is sired against Wayne's full knowledge or in one instance directly against Wayne's will as his mother desired to enslave the Batman to her will, Talia drugged Wayne, and forced herself upon him. The product of their evening together was Ibn al Xu'ffasch. Talia kept Ibn's existence a secret from the Dark Knight, and Batman never learned the truth behind Ibn's parentage.

Terry McGinnis (DCAU)

Amanda Waller used nanotechnology to ensure that Bruce Wayne's DNA overwrote the DNA in Warren McGinnis's sex cells. Making him his biological son.

Huntress (Helena Wayne) {Earth 2}

Helena was born in 1957 to Bruce Wayne and Selina Kyle Wayne, and grew up enjoying the benefits of being in a wealthy household. In 1976, criminal Silky Cernak blackmailed his old boss Selina Kyle into resuming action once again as Catwoman, an act which eventually led to her death. Helena, deciding to bring Cernak to justice, created a costume for herself, fashioned some weapons from her parents' equipment (including her eventual trademark, a crossbow), and set out to bring him in. After accomplishing this, Helena decided to continue to fight crime, under the code name "the Huntress."

Tallant Wayne

The son of both Bruce Wayne and Talia in the Elseworlds world of Batman: league of batman.

Damian Wayne

Damian's origin is unknown to Batman. Genetically perfected and grown in an artificial womb, Damian was intended to be a formidable warrior. He is raised by Talia and the League of Assassins. He becomes a talented martial artist by the time he is a pre-teen, at which time Talia reveals Damian's existence to Bruce Wayne and leaves him in Batman's custody in an effort to disrupt Batman's work.

Bruce Wayne Jr. (Earth-154)

Bruce Wayne, Jr. was the biological son of Bruce Wayne of an alternate reality in which the elder Wayne married and had children. Bruce Wayne Jr. did not truly appreciate his father's legacy, although he did train to the same levels both physically and mentally (as did Dick Grayson, who became Wayne, Sr.'s junior partner Robin).

Bruce Wayne, Jr. (Earth-3839)

Bruce Wayne Jr. was born the son of Bruce Wayne (Batman) and the wife he married around 1949. As a young child he was impressed by his father being Batman and his "Uncle Dick" Grayson being Robin, so much to the point where Alfred the butler found him in the Batcave wearing his uncle's Robin outfit and doing exercises in the hopes of someday becoming the Boy Wonder. His mother, however, wanted Bruce Jr. to not take on the identity of Robin until he was eighteen. Despite her wishes, Bruce Jr. became Robin and worked alongside Clark Kent's (Superman) daughter Kara who became Supergirl in their teens. His eventual partnership with Dick Grayson as Batman was what drove his mother away.

He has two adopted son too Tim Drake (third robin) and Clark Wayne. But only Damian is from main continuity, not sure about Terry's comic counterpart.