London police have issued an arrest warrant for a 29-year-old London woman charged with manslaughter in relation to a fatal hit-and-run on Tuesday.

Brittany Lynn Boyce is charged with one count of manslaughter and one count of assault with weapon.

According to police, Boyce was driving a Pontiac Torrent when she struck Deborah Titus, 64, on Tuesday at about 2 p.m. at the corner of Ashland Avenue and Dundas Street.

Boyce then sped away from the scene.

Titus was rushed to hospital where she died.

Police continue to investigate a fatal hit-and-run in London's east-end. (Andrew Lupton/ CBC News)

Police said Titus was attempting to retrieve stolen property from the car driven by the suspect when she was hit by the vehicle.

A bystander was trying to help Titus. The bystander was dragged by the car and suffered minor injuries.

London police located the car involved in the incident on Wednesday. The owner was co-operating with the investigation.

Const. Sandasha Bough said police are asking the public for help in the investigation.

"The female wanted … has brown eyes, she's slim built and has long, brown curly hair," said Bough.

"We're looking for assistance from the public. If you know of her whereabouts or any information in relation to this incident, please give us a call."