There is, as yet, no scientific consensus on whether or not the G-Spot exists or if female ejaculation is real. Critics of the G-Spot largely focus their arguments on the fact that because so many women do not experience vaginal orgasms, that it must not exist. Additionally, they point out that there is no area inside the vagina with more nerve endings than any other area. They also use the discovery about the clitoris being internal to argue that vaginal orgasms are caused by the same organ, not a separate erogenous zone.

Proponents of the G-Spot argue that the vagina does have an erogenous zone that swells up when excited and that this area provides an additional lubricant when it is sexually aroused. They also show that ultrasound studies show changes to the area during sex.

The debate on female ejaculation is often tied in with the G-Spot argument as proponents argue that ejaculation is tied in with stimulation of the G-Spot. While it is widely accepted that some women have been known to gush fluid during orgasm, the debate largely centers around what the fluid is actually made of. Many critics claim the fluid is simply urine. Some proponents argue that it is a separate substance, while others debate that it is urine; but urine is filled with a unique selection of chemicals, making it qualify as a sexually-induced ejaculation regardless of the connection with the bladder.