* Russia condemns new U.S. defence policy bill

* Accuses Obama administration of trying to influence Trump

* Says hopes new U.S. administration will be 'wiser' (Adds U.S. response)

By Andrew Osborn

MOSCOW, Dec 27 (Reuters) - Russia said on Tuesday that a U.S. decision to ease restrictions on arming Syrian rebels had opened the way for deliveries of shoulder-fired anti-aircraft missiles, a move it said would directly threaten Russian forces in Syria.

Moscow last year launched a campaign of air strikes in Syria to help President Bashar al-Assad and his forces retake territory lost to rebels, some of whom are supported by the United States.

Foreign Ministry spokeswoman Maria Zakharova said the policy change easing restrictions on weapons supplies had been set out in a new U.S. defense spending bill and that Moscow regarded the step as a hostile act.

U.S. President Barack Obama, who has been sharply critical of Russia's intervention in Syria, signed the annual defense policy bill into law last week.

State Department spokesman Mark Toner dismissed the Russian charges, saying the administration remains opposed to providing portable anti-aircraft missiles, or MANPADS, to Syrian opposition groups.

"Our position on MANPADS has not changed. We have a very deep concern about that kind of weaponry getting into Syria," Toner said, referring to fears that portable anti-aircraft missiles could end up in the hands of Islamist militants and be used against civilian airliners.

The National Defense Authorization Act, signed into law by Obama on Dec. 23, appears designed to assuage the administration's misgivings but imposes a new layer of congressional oversight on any presidential decision to provide them.

A provision bars the U.S. Defense Department from spending funds on MANPADS for Syrian rebel groups until the secretaries of state and defense submit a report to congressional committees explaining the decision to do so.

The report would have to include which groups would receive the weapons, intelligence analyses on the groups and the kinds and numbers of MANPADS to be supplied.

Moscow cast the bill as lifting restrictions on the provision of such weapons to Syrian rebels.

"Washington has placed its bets on supplying military aid to anti-government forces who don't differ than much from blood thirsty head choppers. Now, the possibility of supplying them with weapons, including mobile anti-aircraft complexes, has been written into this new bill," Zakharova said in a statement.

"In the administration of B. Obama they must understand that any weapons handed over will quickly end up in the hands of jihadists," she added, saying that perhaps that was what the White House was counting on happening.

The U.S. decision was a direct threat to the Russian air force, to other Russian military personnel, and to Russia's embassy in Damascus, said Zakharova.

"We therefore view the step as a hostile act."

Zakharova accused the Obama administration of trying to "put a mine" under the incoming administration of President-elect Donald Trump by attempting to get it to continue what she called Washington's "anti-Russian line."

The Obama administration has in recent weeks expanded the list of Russians affected by U.S. sanctions imposed on Moscow over its actions in Ukraine.

Trump, during his election campaign, said he was keen to try to improve relations with Moscow and spoke positively about President Vladimir Putin's leadership skills.

A back-and-forth exchange between Trump and Putin over nuclear weapons last week tested the Republican's promises to improve relations with Russia however.

The Obama administration and U.S. intelligence officials have accused Russia of trying to interfere with the U.S. election by hacking Democratic Party accounts.

"The current occupants of the White House imagined that they could pressure Russia," said Zakharova. "Let's hope that those who replace them will be wiser." (Additional reporting by Peter Hobson in Moscow and Tom Perry in Beirut and Jonathan Landay and Lesley Wroughton in Washington; Editing by Raissa Kasolowsky and Alan Crosby)

Our Standards: The Thomson Reuters Trust Principles.