It looks like “Breakfast at Tiffany’s” will finally reach Broadway, some 46 years after a musical adaptation became one of the most legendary flops in theater history. “Truman Capote’s ‘Breakfast at Tiffany’s,’” a new play version by Tony Award winner Richard Greenberg (“Take Me Out”), will begin performances on Broadway in February 2013 at a Shubert Organization theater to be announced later, the producers said on Wednesday.

The play will star the British actress Emilia Clarke (HBO’s “Game of Thrones”) as New York society girl Holly Golightly; the director will be Sean Mathias, a Tony nominee in 1995 for staging “Indiscretions.” The Capote estate has been trying for years to develop a stage production of “Breakfast at Tiffany’s,” a novella by Mr. Capote that was published in 1958 and was made into a film in 1961 starring Audrey Hepburn (who was nominated for an Academy Award as Holly).

Mr. Mathias directed a different play adaptation of “Breakfast at Tiffany’s” in London in 2009, starring Anna Friel; the production received mixed to negative reviews. The producers are Colin Ingram Productions Ltd. (“Ghost the Musical”), Donovan Mannato, and Dominic Ianno.

The first attempt at a Broadway musical version of “Breakfast at Tiffany’s,” with a score by Bob Merrill (“Funny Girl”) and a book by Pulitzer Prize-winning playwright Edward Albee, was scuttled after just four preview performances in December 1966 after producer David Merrick decided that the show would flop.

“The goal of this version is to return to the original setting of the novella, which is the New York of the Second World War, as well as to resume its tone — still stylish and romantic, yes, but rougher-edged and more candid than people generally remember,” Mr. Greenberg said in a statement.