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To the Editor: A 21-year-old nonsmoking woman with a history of asthma was seen for wheezing and dyspnea of six weeks' duration; these symptoms had been treated with adjusted doses of theophylline preparations, inhaled beta-agonists, and inhaled steroids. There was a persistent dry cough, but the chest roentgenogram was normal. The patient had been using Crest Tartar Control toothpaste (Procter and Gamble, Cincinnati), but when she switched to a gel-based toothpaste her wheezing resolved dramatically. Rechallenge with any paste-based toothpaste caused wheezing within 10 minutes. Pulmonary-function tests were performed before and after exposure to paste-based toothpaste, as well as after . . .