Defense Minister Avigdor Lieberman said Tuesday that Israel may strike the Russian-made S-300 anti-aircraft defense systems in Syria if they are used against Israel.

"One thing should be clear - if someone fires on our planes, we will destroy them," Lieberman said in an interview with the Israeli website Ynet. "What's important to us is that the weapons defense systems that the Russians transfer to Syria are not used against us. If they are used against us, we will act against them."