The best college football programs typically have the most intimidating home environments. Few teams enjoy the experience of visiting venues such as Alabama’s Bryant-Denny Stadium or Oregon’s Autzen Stadium.

But, according to one study, the biggest home-field advantage in college football belongs to a much less-heralded program: North Texas. Prediction Machine, a statistical outlet that simulates games, studied which teams have the biggest home-field advantage since 2000, comparing home performance relative to road performance,...