Melania Trump Erin Scott/Reuters

First lady Melania Trump was booed for about 30 seconds at an opioid-awareness event attended by middle- and high-school students in Baltimore on Tuesday.

The Trumps have a troubled relationship with the city.

President Donald Trump made disparaging remarks about Baltimore in July, referring to it as a „disgusting rat- and rodent-infested mess.“

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First lady Melania Trump on Tuesday was loudly booed at an antidrug event in Baltimore for middle- and high-school students.

The booing lasted for about 30 seconds as Trump was introduced at the Baltimore Youth Summit on Opioid Awareness. As Trump began to speak, some in the crowd continued to jeer at her.

Talking over the audience, Melania said: „Thank you to all of the students who are here. I am so proud of you for the bravery it takes to share that you have been strongly affected by the opioid epidemic in some way.“

The first lady’s appearance occurred as part of her „Be Best“ initiative, which focuses on three main pillars: „well-being, online safety, and opioid abuse.“

Kate Bennett, of CNN, whose reporting focuses on the first lady, said she could not recall an event where the first lady was so negatively received.

Bennett, who was at the event, said she believed this was the first loud booing at a solo event for Trump.

The first lady responded to the booing in a statement later in the day. She said: „We live in a democracy and everyone is entitled to their opinion, but the fact is we have a serious crisis in our country and I remain committed to educating children on the dangers and deadly consequences of drug abuse.“

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.@FLOTUS was loudly booed as she took the stage at a youth summit for opioid awareness in Baltimore today. pic.twitter.com/7DiQ5ntPCi

The Trumps have a troubled relationship with Baltimore.

President Donald Trump made disparaging remarks about Baltimore in July, referring to it as a „disgusting rat- and rodent-infested mess.“ The president was attacking the late Elijah Cummings, the Democratic lawmaker whose congressional district included much of Baltimore. Cummings died in mid-October.

Trump was widely decried over his remarks on Baltimore, particularly for suggesting that „no human being would want to live“ in Cummings‘ district.