Grosse Ile police are seeking assistance in finding a missing 51-year-old mother.

Christine Chiles was last seen Friday at 4 a.m. Police said the mother of three may be suffering from depression. She was wearing gray sweatpants and a baggy beige sweater.

Officers searched Chiles' home and the immediate area, which has included parts of the Detroit River and areas of open space. A K9 unit attempted to track her scent, but was unsuccessful.

St. Joseph Catholic Church in Trenton said they were holding a prayer vigil Saturday following afternoon Mass "to pray for her and her family."

Residents conducted search parties around the island Friday and Saturday, according to the Facebook group Grosse Ile Now. Concerned citizens are going door-to-door asking for surveillance footage, as well as checking out buildings, garages, docks and boats. As of 6:30 p.m. Saturday, a majority of Grosse Ile had been searched with the exception of Grosse Ile Municipal Airport, Powder House, Fox and Celeron islands and some residential areas.

Police has requested assistance from the Wayne County Sheriff-Marine Division and the Cost Guard in the search.

Chiles is described as being 5 foot 10 inches, 125 pounds, with long blonde hair.

Anyone with information is asked to call Grosse Ile police at 734-676-7100.

More:Police: Man found in Detroit River was reported missing from Windsor

More:Missing 15-year-old Michigan girl found at Rhode Island man's home