The trailblazing entry of regenerative medicine in research and therapies has opened new avenues for medicine.

The field of medicine growing by leaps and bounds. The penetration of breakthrough technology and cutting-edge research has given new hope to medicine. Regenerative medicine is one such new class of cell therapies that can potentially alter the course of treatments for damaged organs and debilitating diseases. By accelerating the pace at which the human body heals, these treatments are gaining their foothold in the medical arena. There is a greater incidence of chronic diseases and trauma emergencies in the world populace. Stem cell technology and nanotechnology are gaining popularity as they are changing the way a patient recovers. This has opened up new growth revenues for the regenerative medicine market.

Allied Market Research has recently published a report titled, regenerative medicine market that is an in-depth study of the market state, size and growth drivers for the mentioned period. It also forecasts of revenues for different regions across the world. The industry is transforming the idea of traditional medicines and treatments, by converting fear into hope.

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Stem cell research—Stepping stone for regenerative treatments

The medical field is engaged extensively in researching and harnessing the potential promised by stem cell therapies. Cellular therapies like these aim at finding the right cells in our body and transplanting them to targeted areas. Clinical scientists are engaged in studying how stem cells function, transform, or differentiate. This is an exciting possibility where directing these regenerative stem cells into specialized cells can provide a renewable source of replacement for those suffering from chronic diseases. The application of this therapy has been found useful in treating maladies, such as Parkinson’s disease, Type 1 diabetes, arthritis, cardiovascular disease. Stem cells can also be beneficial to the pharmaceutical field by allowing testing of new drugs on them. Testing on stem cells helps assess the safety of these drugs, before doing it on humans or animals. Effective treatment of disease, or in some cases, even reversal of ailments through stem cell therapy have paved the way for regenerative medicine.

Researchers are San Diego University, California have made a new discovery in the usage of pluripotent stem cells for bone tissue regeneration. Shyni Varghese, a bioengineering professor at UC San Diego and senior author of the study, along with her team, achieved this by feeding these cells with adenosine, a naturally occurring molecule in the body. Pluripotent stem cells are capable of initiating direct cell differentiation, which is a complex process. After transplantation, it can sometimes develop into tissues that lead to formation of teratomas or tumors. By controlling the differentiation of human pluripotent cells, Varghese and her team showed that they could turn these into functional osteoblasts (bone-building cells). They achieved this simply by adding the molecule adenosine to their growth medium. The resulting osteoblasts formed new bone tissues upon transplantation in mice, without any signs of teratomas formation.

"It's amazing that a single molecule can direct stem cell fate. We don't need to use a cocktail of small molecules, growth factors or other supplements to create a population of bone cells from human pluripotent stem cells like induced pluripotent stem cells," Varghese said. Medical advancements such as there are testimonial to the fact that regenerative medicine market is here to stay.

Reconstructive Surgery—Potential game-changer for regenerative medicine

The emergence of reconstructive surgery has opened new avenues for regenerative medicine. Plastic surgeons and researchers are focusing on treatments for people with congenital anomalies through developing regenerative medicine-based treatments. These therapies, also known as facial plastic and reconstructive surgery (FPRS) will benefit for people who suffer from cleft lip and cleft palate, burns, limb and muscle loss, facial aging, facial nerve injuries, breast cancer, and other reconstructive needs. These employ the use of soft-tissue and bony regeneration strategies, including synthetic scaffolds, constructs that can be implanted with or without cells or growth factors in the regeneration of tissues.

“The field of regenerative medicine aims at enhancing tissue healing and regeneration through the exogenous addition of therapeutic growth factors and cells, often in combination with tissue-compatible scaffolds,” Matthew Q. Miller, MD, of the department of otolaryngology head and neck surgery, University of Virginia Health System, Charlottesville, Virginia. FPRS has augmented the regenerative medicine market growth, by widening the scope of the industry.

The world regenerative medicine market is set to witness an exponential growth in the coming few years. Increasing number of degenerative diseases and organ transplantation can push forth the growth of this market. There is widespread investment in this industry, since the cost of research and experiments is comparatively high. Technological advancements in tissue and organ regeneration, FPRS, stem cell technology, and nanotechnology are constantly being explored. The market promises various opportunities for the development of medicines that facilitate the natural wound-healing mechanisms in human body, and improve life expectancies. With so many stakes involved in the industry, the regenerative medicine market is set to be a potential game-changer in the field of medicine.



