Donald Trump may face off in 2020 against another TV star, best-selling author and wildly successful entrepreneur with zero political experience — Oprah Winfrey.

Winfrey — a staunch liberal who backed Hillary Clinton and is pals with former President Barack Obama — slyly hinted that she might reconsider a presidential run.

In an interview with Bloomberg TV, Winfrey, 63, said she never considered running before because of her lack of political experience. But now, with the political neophyte Trump in the White House, she just might change her mind.

“I thought, ‘Oh, gee, I don’t have the experience, I don’t know enough!’” she said. “Now I’m thinking, ‘Oh. Oh.’ ”

As recently as last month, Winfrey ruled out a White House run, telling CBS’s “Late Show” host Stephen Colbert, “No, it’s not my thing.”

During the campaign, Winfrey slammed Trump, 70, without mentioning his name.

“Do you like this country? You better get out there and vote. Do you like the country? Do you like freedom and liberty? Do you like democracy? Or do you want a demagogue?” she said.

While both are billionaires — with Winfrey’s net worth at $3 billion and Trump’s at $3.7 billion, according to Forbes — Winfrey is self-made while Trump inherited the family business.

Not all Democrats cheered the news.

“I love Oprah, but Democrats need to focus on local and state races right now, and not just obsess about hypothetical presidential match-ups that are four years away,” said ex-Hillary Clinton campaign spokesman Brian Fallon.

Additional reporting by ­Daniel Halper