What they did

The authors conducted a double blind RCT over 4 years for patient between 3 months and 18 years with status epilepticus. The study included 273 patients; 140 randomized to 0.2mg/kg of IV diazepam and 133 randomized to 0.1mg/kg of IV lorazepam. The dose of each drug was repeated at 5 minutes, followed by fosphenytoin if there was no cessation of seizures. The primary outcome was stoppage of seizures at 10 minutes without recurrence by 30 minutes.