Burnout in doctors has devastating consequences on the quality of care they deliver, according to a large scale systematic review and meta-analysis.

The study, by experts at the Universities of Manchester, Keele, Leeds, Birmingham and Westminster, looks at 47 papers which together analyse the responses of 43,000 doctors.

This NIHR School for Primary Care Research and NIHR Greater Manchester Patient Safety Translational Research Centre funded study is published today in the journal JAMA Internal Medicine.

It finds that doctors with burnout are twice as likely to make mistakes, such as incorrect diagnoses or wrong prescriptions. Preventable harmful medical errors occur in 1 in 20 patients according to a recent GMC report. Burnout also doubles the likelihood of lower professional standards, such as not following NICE guidelines or malpractice.

Professor Carolyn Chew-Graham, Professor of General Practice Research at Keele University said:

"As a GP, I am well aware of the impact of stress in clinicians, on the individual and their colleagues. This study provides evidence that physician burnout potentially jeopardises patient care and patient safety. This reinforces the need for policy-makers to ensure that healthcare systems support clinicians, and that clinicians recognise symptoms of burnout in themselves and others, and either seek or offer help and support. A sick workforce cannot provide good patient care."

And burnout, argues Dr Maria Panagioti from The University of Manchester, who led the study, may be impacting on dropping patient satisfaction.

The study found that patient satisfaction is three times more likely to be lower when doctors are physically, emotionally and mentally exhausted – core signs by which experts identify burnout.

Though it has been traditionally considered high, public satisfaction with NHS has dropped from 63% in 2016 to 57% in 2017 – a drop of 6 percentage points.

Another worrying finding of the study is that in junior doctors in particular, burnout increases the likelihood of lower professional standards by 3.5 times. A recent General Medical Council survey of 52,000 UK trainee doctors found that one in four trainees feel burnt out.

Dr Maria Panagioti, Senior Research Fellow at the Centre for Primary Care, Manchester University said:

“This meta-analysis provides a snapshot of what happens to patients when their doctors are burnt out. We show conclusively that the provision of safe, high quality patient care is severely compromised when doctors are physically, emotionally and mentally exhausted. Clearly, this is not is not the fault of doctors. It’s caused by a combination of factors including high workload, the way teams work together, and the absence of measures which improve wellbeing. But it’s also about a performance culture which in recent years has become more prevalent in the medical profession. Doctors are increasingly being asked to be superhuman, when they are not. They need care and attention that anyone would need when under such enormous pressure and that is just not happening. “NHS bodies need to look at workload, improved team working, and making time to meet with other doctors. Our previous studies show approaching individuals on case-by-case basis is not effective, and the issue should instead be tackled with organisation-wide initiatives. Resilience training such as mindfulness courses which are time-protected and financially supported by healthcare organisations are helpful too.”

Dr Ruth Riley, of the University of Birmingham’s Institute of Applied Health Research, said: