Theresa May has urged voters not to worry about Brexit, despite her government setting out plans to stockpile food, blood and medicine in case it goes badly.

She said people should take “reassurance and comfort” from news of the plans, to be implemented if the UK crashes out of the EU without an agreement in March next year.

The scenario is looking increasingly likely given deep divisions in the Conservatives over Ms May’s approach, her wafer thin commons majority and the EU’s on-going resistance to what the prime minister is proposing.

Chuka Umunna and John Rentoul debate the possibility of another Brexit referendum

It comes as The Independent launched a campaign to give the British people a Final Say in a referendum on whatever is proposed at the end of Brexit negotiations, with thousands flocking to sign a petition supporting the cause.

Ireland’s deputy prime minister accused the PM of “bravado” in talking up the dangers of a no-deal Brexit, while Tory insiders claim the PM is doing so to warn her rebellious MPs of the consequence of failing to back her unpopular Brexit plans.

Ms May confirmed in a TV interview that plans for stocking up on essential goods are underway, in case imports from the EU are cut off by clogged ports or regulatory disputes.

But, asked if it was “alarming” for people, the prime minister told Channel 5: “Far from being worried about preparations that we are making, I would say that people should take reassurance and comfort from the fact that the government is saying we are in a negotiation, we are working for a good deal.

“I believe we can get a good deal, but, it’s right that we say – because we don’t know what the outcome is going to be – let’s prepare for every eventuality.”

She added: “This is not just about stockpiling. That concept, what it is, is about making sure that we will be able to continue to do the things that are necessary once we have left the European Union, if we leave without a deal.”

Matt Hancock talks about stockpiling of blood products in the event of a no deal Brexit

It came after health secretary Matt Hancock admitted he had already met with industry leaders to discuss building up NHS reserves of vaccinations, medical devices, clinical consumables and blood products if Britain crashes out of the EU without a deal.

Dominic Raab, the new Brexit secretary, also recently confirmed preparations were being made to stockpile food, as ministers ramp up planning in case the negotiations fail.

Simon Coveney, Dublin’s deputy prime minister, urged Britain to delay Brexit if the talks remain deadlocked – offering to press for an extension to the Article 50 deadline.

Asked about talk of a no-deal Brexit in the UK, he said: “I have heard a lot of comment on this issue in recent weeks and, to be honest with you, I think some of it is bravado.

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Tens of thousands of people demonstrated in London on Saturday calling for a second vote on Britain's departure from the European Union. / AFP PHOTO / Niklas HALLE'NNIKLAS HALLE'N/AFP/Getty Images NIKLAS HALLE'N AFP/Getty Images People's Vote march – demanding vote on final Brexit deal A young protestor shouts as she takes part in the People's Vote demonstration against Brexit Getty Images People's Vote march – demanding vote on final Brexit deal A woman holds a placard as she joins EU supporters, calling on the government to give Britons a vote on the final Brexit deal, participating in the 'People's Vote' march in central London, Britain June 23, 2018. REUTERS/Henry Nicholls HENRY NICHOLLS Reuters People's Vote march – demanding vote on final Brexit deal epa06833888 Pro-EU demonstrators take part in a People's March anti-Brexit rally in Parliament Square in London, Britain, 23 June 2018. Protesters are calling for a referendum on the final deal. The protest is taking place on the second anniversary of the Brexit referendum. EPA/ANDY RAIN ANDY RAIN EPA People's Vote march – demanding vote on final Brexit deal A protester's pro-EU t-shirt EPA People's Vote march – demanding vote on final Brexit deal epa06833892 A pro-EU demonstrator waves a European Flag during a People's March anti-Brexit rally in Parliament Square in London, Britain, 23 June 2018. Protesters are calling for a referendum on the final deal. The protest is taking place on the second anniversary of the Brexit referendum. EPA/ANDY RAIN ANDY RAIN EPA People's Vote march – demanding vote on final Brexit deal Demonstrators carry banners and flags as they participate in the People's March demanding a People's Vote on the final Brexit deal, in central London on June 23, 2018, the second anniversary of the 2016 referendum. Tens of thousands of people demonstrated in London on Saturday calling for a second vote on Britain's departure from the European Union. / AFP PHOTO / Niklas HALLE'NNIKLAS HALLE'N/AFP/Getty Images NIKLAS HALLE'N AFP/Getty Images People's Vote march – demanding vote on final Brexit deal epa06833960 Tens of thousands of people march through London during a People's March anti-Brexit demonstration in London, Britain, 23 June 2018. Protesters are calling for a referendum on the final deal. The protest is taking place on the second anniversary of the Brexit referendum. EPA/ANDY RAIN ANDY RAIN EPA People's Vote march – demanding vote on final Brexit deal Leader of the Liberal Democrats, Vince Cable speaks during the People's March demanding a People's Vote on the final Brexit deal, in central London on June 23, 2018, the second anniversary of the 2016 referendum. Tens of thousands of people demonstrated in London on Saturday calling for a second vote on Britain's departure from the European Union. / AFP PHOTO / Niklas HALLE'NNIKLAS HALLE'N/AFP/Getty Images NIKLAS HALLE'N AFP/Getty People's Vote march – demanding vote on final Brexit deal epa06833964 A young pro-EU demonstrator takes part in a People's March anti-Brexit rally in Parliament Square in London, Britain, 23 June 2018. Protesters are calling for a referendum on the final deal. The protest is taking place on the second anniversary of the Brexit referendum. EPA/ANDY RAIN ANDY RAIN EPA People's Vote march – demanding vote on final Brexit deal Gina Miller and Caroline Lucas EPA People's Vote march – demanding vote on final Brexit deal epa06834044 Tens of thousands of people march through London during a People's March anti-Brexit demonstration, in London, Britain, 23 June 2018. Protesters are calling for a referendum on the final deal. The protest is taking place on the second anniversary of the Brexit referendum. EPA/ANDY RAIN ANDY RAIN EPA People's Vote march – demanding vote on final Brexit deal epa06833264 Thousands of people march through London during a People's March anti Brexit demonstration in London, Britain, 23 June 2018. Protesters are calling for a referendum on the final deal. The protest is taking place on the second anniversary of the Brexit referendum. EPA/ANDY RAIN ANDY RAIN EPA People's Vote march – demanding vote on final Brexit deal Tens of thousands of people march through London EPA People's Vote march – demanding vote on final Brexit deal epa06833265 Thousands of people march through London during a People's March anti Brexit demonstration in London, Britain, 23 June 2018. Protesters are calling for a referendum on the final deal. The protest is taking place on the second anniversary of the Brexit referendum. EPA/ANDY RAIN ANDY RAIN EPA People's Vote march – demanding vote on final Brexit deal Demonstrators at the People's Vote March Getty People's Vote march – demanding vote on final Brexit deal 'Two months too young to decide on my future' REUTERS People's Vote march – demanding vote on final Brexit deal Crowds taking part in the People's Vote march for a second EU referendum at Trafalgar Square in central London. PRESS ASSOCIATION Photo. Picture date: Saturday June 23, 2018. See PA story POLITICS Brexit. Photo credit should read: John Stillwell/PA Wire John Stillwell PA People's Vote march – demanding vote on final Brexit deal A young girl joins in the march PA People's Vote march – demanding vote on final Brexit deal An EU flag is draped across the statue of Winston Chruchill in Parliament Square REUTERS People's Vote march – demanding vote on final Brexit deal Demonstrators gather prior to the start of the People's March demanding a People's Vote on the final Brexit deal, in central London on June 23, 2018, on the second anniversary of the 2016 referendum. / AFP PHOTO / Niklas HALLE'NNIKLAS HALLE'N/AFP/Getty Images NIKLAS HALLE'N AFP/Getty Images People's Vote march – demanding vote on final Brexit deal Vince Cable MP, Pro-EU campaigner Gina Miller, Tony Robinson and Caroline Lucas MP join with crowds PA People's Vote march – demanding vote on final Brexit deal Crowds gather on Pall Mall in central London, during the People's Vote march for a second EU referendum. PRESS ASSOCIATION Photo. Picture date: Saturday June 23, 2018. See PA story POLITICS Brexit. Photo credit should read: John Stillwell/PA Wire John Stillwell PA People's Vote march – demanding vote on final Brexit deal Crowds gather on Pall Mall PA People's Vote march – demanding vote on final Brexit deal A man resembling Britain's Foreign Secretary Boris Johnson, joins EU supporters Reuters People's Vote march – demanding vote on final Brexit deal EU supporters, calling on the government to give Britons a vote on the final Brexit deal, participate in the 'People's Vote' march in central London, Britain June 23, 2018. REUTERS/Henry Nicholls HENRY NICHOLLS Reuters People's Vote march – demanding vote on final Brexit deal People gather in Trafalgar Square REUTERS People's Vote march – demanding vote on final Brexit deal Pro-EU campaigner Gina Miller and Tony Robinson PA People's Vote march – demanding vote on final Brexit deal EU supporters, calling on the government to give Britons a vote on the final Brexit deal, participate in the 'People's Vote' march REUTERS

“The truth is that I don’t believe Britain can afford to have no-deal on Brexit. I don’t believe that Ireland and the EU want that either.”

The government will issue a series of “technical notices” in the coming months, designed to prepare the public and businesses for the worst-case scenario of leaving without a deal.

The International Monetary Fund has warned the overall UK economy would suffer far more than the EU’s – losing 4 per cent of national output, compared with 1.5 per cent across the Channel.

The Independent launched a campaign for the British people to have a Final Say on the Brexit deal agreed with Brussels on Tuesday, with Dominic Grieve, Labour MP Chuka Umunna and Liberal Democrat MP Layla Moran making the case.

On Wednesday a petition was launched to back the campaign with thousands flocking to sign in within hours.