Barbara Winton issued a personal appeal to the Prime Minister amid a mounting storm over the future of the programme for resettling lone youngsters in the UK.

Ms Winton’s late father helped 669 mostly Jewish children flee Nazi-occupied Czechoslovakia just before the outbreak of the Second World War.

In a letter to the Prime Minister, she wrote: “Donald Trump’s refugee ban echoes the terrible failures of the human spirit that, on the eve of the Second World War, saw country after country close its borders to Jewish refugees in urgent need of protection.

“My father ... knew that each and every one of us share in a responsibility to our fellow men and women, a responsibility to offer sanctuary those fleeing persecution.

“‘If it’s not impossible’, he used to say, ‘then surely something could and something must be done’.”

The so-called Dubs Amendment, named after its architect the Labour peer Lord Alf Dubs, requires the Government to relocate unaccompanied refugee children from other countries in Europe.

It emerged on Wednesday that a total of 350 youngsters will arrive under the scheme, sparking a furious backlash from campaigners and politicians who had originally campaigned for 3,000 to resettled.

Ms Winton went on: “The Government has now announced the total figure of children to be helped through Alf’s amendment and, sadly, has announced a close to the programme.

“Every single child’s life is worth every single thing we can give. That the country has taken any of these children shows my father’s spirit lives on.

“As my father’s MP, I know he deeply valued the relationship he had with you towards the end of his life, and at his memorial you very generously described him as ‘an enduring example of the difference that good people can make even in the darkest of times’ and said ‘I hope that his life will serve as an inspiration for us all... and encourage us to do the right thing’.

“As the world once again teeters on the edge of dark times, I ask you to remember those words.”

Controversy erupted over the Dubs scheme after it emerged that it would come to an end after 150 unaccompanied children are brought to Britain, on top of 200 who have already arrived through the programme.

Britain's Schindler Nicolas Winton dies 106

The Government was not tied under the amendment to any specific figure, but the announcement on Wednesday drew an angry response from critics who expected the final number to be far higher.

As the furore continued on Thursday, the Archbishop of Canterbury added his voice to a chorus of protests.

The Most Reverend Justin Welby said he was “saddened and shocked” at the Government’s decision to limit the number to 350.

Calais Refugee Children arrive in UK Show all 9 1 /9 Calais Refugee Children arrive in UK Calais Refugee Children arrive in UK A coach carrying the first group of unaccompanied minors from the Jungle migrant camp in Calais to be brought to Britain arrives at an immigration centre in Croydon, south London Reuters Calais Refugee Children arrive in UK A Catholic priest chats to Muslim Imans as they wait for the arrival of the coach carrying the first group of unaccompanied minors from the Jungle migrant camp in Calais to be brought to Britain arrives at an immigration centre in Croydon, south London Reuters Calais Refugee Children arrive in UK Fourteen migrant children from the 'Jungle Camp' in Calais are due to arrive in the UK today to be reunited with relatives Getty Calais Refugee Children arrive in UK Young men are escorted after stepping off a coach at the Home Offices Lunar House Getty Calais Refugee Children arrive in UK A boy is escorted after stepping off a coach at the Home Offices Lunar House after arriving from the Calais 'Jungle Camp' Getty Calais Refugee Children arrive in UK UK Border Force staff escort the first group of unaccompanied minors from the Jungle migrant camp in Calais to be brought to Britain as they arrive at an immigration centre in Croydon, south London Reuters Calais Refugee Children arrive in UK A young boy arrives on a coach at the Home Offices Lunar House after leaving the Calais 'Jungle Camp.' Fourteen migrant children from the 'Jungle Camp' in Calais are due to arrive in the UK today to be reunited with relatives Getty Calais Refugee Children arrive in UK British former Archbishop of Canterbury Rowan Williams, center, flanked by Bethany Gardiner-Smith, left, from the Citizens UK charity and Bishop of Croydon Jonathan Clark speaks to the media about the 14 migrant children who will be resettled in the UK, outside Croydon Minster church in Croydon, south London AP Calais Refugee Children arrive in UK Asif Khan whose brother Aimal Khan was one of fourteen migrant children who arrived in the UK, speaks to the media outside Lunar House in Croydon, south London. The 25-year-old chef has been living in the UK for 11 years, having fled Afghanistan himself. His brother Aimal Khan, 14, also from Afghanistan, had been stranded in the Jungle for six months PA

Ms May insisted the Government’s approach to assisting refugees is “absolutely right”, while Home Secretary Amber Rudd defended the approach to the Dubs scheme – saying British and French authorities feared it was acting as a “pull factor” for children to head to the UK and provided opportunities for people-traffickers.

The Home Office has insisted it is not giving up on vulnerable children and youngsters will continue to arrive from around the world through other resettlement schemes and the asylum system.

In total, more than 900 unaccompanied children were transferred to the UK from Europe last year.