Get ready to see Agents of S.H.I.E.L.D.'s FitzSimmons like you've never seen them before.

Everyone's favorite lovebird lab rats are getting animated for an upcoming episode of Disney XD's Marvel's Ultimate Spider-Man Vs. The Sinister 6 and E! News has your first look at Elizabeth Henstridge and Iain de Caestecker's cartoon counterparts!

In the March 13 episode of the animated hit's fourth season, de Caestecker's Leo Fitz and Henstridge's Jemma Simmons find themselves wrapped up in the adventure when Vulture's revelation that Doc Ock has a spy inside S.H.I.E.L.D. Academy leads the Web Warriors on a hunt to find the mole. When they confront Dr. Curt Connors, he turns himself into The Lizard and attacks S.H.I.E.L.D. with a venomous bite that spreads like a virus and turns its victims into lizards.