PITTSBURGH — Federal prosecutors said on Monday that they would seek the death penalty for the man accused of killing 11 worshipers in a Pittsburgh synagogue in October, in what has been called the deadliest anti-Semitic attack in United States history.

In a court filing, they argue that “a sentence of death is justified” by the circumstances in 22 of the 63 federal charges against the man, Robert D. Bowers, citing his motivation and his “lack of remorse.”

The suspect, prosecutors said, “targeted men and women participating in Jewish religious worship at the Tree of Life Synagogue, located in the Squirrel Hill neighborhood of Pittsburgh, Pennsylvania, which is home to one of the largest and oldest urban Jewish populations in the United States, in order to maximize the devastation, amplify the harm of his crimes, and instill fear within the local, national and international Jewish communities.”

The decision was announced in a filing with the United States District Court for the Western District of Pennsylvania. It comes one month after Attorney General William Barr announced that the Justice Department would be resuming capital punishment for federal prisoners, which had been essentially on moratorium since 2003.