Rock band Guns N' Roses have been booed at their concert on Tuesday night after they greeted the MCG crowd as "Sydney".

A crowd already restless after waiting nearly an hour for the band's appearance replaced roaring cheers with a chorus of boos when they heard the slip up.

The core original members of Axl Rose, Slash and Duff McKagan bounded on stage with the rest of the band undaunted, while the 70,000 strong crowd seemed a little bemused.

"You're in Melbourne," yelled one crowd member as the rockers burst into opening song It's So Easy and fireworks lit up the stage.