INDIANAPOLIS — The Indiana State Health Department says 16 more Hoosiers have died from COVID-19 bringing the total number of deaths in the state to 65.

An additional 406 cases were also reported among the 1,000 new tests.

This would be Indiana's biggest single-day numbers increase since the pandemic began, although ISDH said during their Monday briefing that those numbers could not be attributed to a single day — because the test results are delayed for different reasons.

The number of cases of COVID-19 in Marion County is now over 1,100 with 21 deaths reported.

The Delaware County Health Department says their most recent cases were a 30-year-old female who is currently at home and under isolation and a 60-year-old male who is hospitalized in an unknown condition.

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Human coronaviruses most commonly spread from an infected person to others through:

Respiratory droplets released into the air by coughing and sneezing

Close personal contact, such as touching or shaking hands

Touching an object or surface with the virus on it, then touching your mouth, nose, or eyes before washing your hands

Rarely, fecal contamination.

The best way to protect yourself from any respiratory illness, including the flu, is to: