FOR six decades, a magazine has been putting the “Mad” in Madison Avenue by lampooning — and frequently harpooning — the huckstering of the advertising industry.

The magazine is, of course, Mad, which is celebrating its history of “humor in a jugular vein,” as its slogan once promised, with an anthology to be published on Tuesday titled “Totally Mad: 60 Years of Humor, Satire, Stupidity and Stupidity.” Among the 256 pages of the $34.95 book are generous samples of the wicked ad spoofs, parodies and sendups — takeoffs, as the editors call them — that have been an intrinsic part of Mad since the debut issue in August 1952.

“Of course I grew up reading Mad magazine,” said David Lubars, chairman and chief creative officer at BBDO North America, part of the BBDO Worldwide unit of the Omnicom Group. “I still have in a box somewhere issues from the ’60s that I’m sure are dog-eared and coverless.”

The knowing attitude of Mad’s mockery helped the readers who grew up to join the business realize they must sell “a skeptical audience,” Mr. Lubars said.