The Padres will have right fielder Wil Myers and third baseman Christian Villanueva in the lineup Friday night against the Diamondbacks.

Myers, who hit two home runs in his three-game rehab assignment in Lake Elsinore, is set to come off the disabled list before the 6:40 game. Villanueva, who was hit in the left hand by a pitch Wednesday, is also expected to play.

Villanueva has 10 hits (including two doubles and three home runs) in 17 at-bats during a six-game hitting streak. He has walked five times and been hit twice in those games.

Myers had three hits, including a home run, in the five at-bats that preceded his leaving the Padres’ April 2 game against the Rockies with nerve irritation in his right arm. His return puts the depleted Padres outfield closer to full strength.


Center fielder Manuel Margot, on the DL since April 11, had six at-bats in extended spring training games Thursday and is playing there again Friday. He is eligible to come off the DL on Saturday.

The Padres will likely send down reliever Tyler Webb, who was called up Wednesday and pitched in the final two games of the Dodgers series. Reliever Kirby Yates (ankle) is also coming off the DL in time for Friday’s game.

kevin.acee@sduniontribune.com