Crystal methamphetamine or "ice" is causing increasing harm in Victoria, with new figures showing that the number of ambulance call outs for patients affected by the drug is continuing to climb.

Ambulance Victoria data shows paramedics treated 592 patients affected by ice across Melbourne in 2011-12, a 110 per cent rise from 282 patients in 2010-11.

Ambulance Victoria data shows paramedics treated 592 patients affected by ice in Melbourne in 2011-12. Credit:John Donegan

The increase follows large jumps in ice-related calls over the previous few years, resulting in a 335 per cent increase from 136 calls in 2009-10.

Turning Point researcher Belinda Lloyd said ice had the potential to cause severe mental and physical effects, particularly when used with other drugs.