US stand-up comedian Dave Chappelle has sparked outrage after making a joke about one of the victims of Louis CK, who was accused of harassment and inappropriate sexual behaviour by five women in November 2017.

"One lady said, 'Louis C.K. masturbated in front of me, ruined my comedy dreams,'" Chappelle said during his pre-recorded show The Bird Revelation, which premiered on Netflix on New Year's Eve.

"Word?' Well then I dare say, Madam, you may have never had a dream. Come on man, that's a brittle spirit. That is a brittle-ass spirit, that is too much, this grown-ass woman."

He then added: "Show business is just harder than that. I know that sounds f----- up, I'm not supposed to say that, but one of these ladies was like, 'Louis CK was masturbating while I was on the phone with him.' Bitch, you don't know how to hang up a phone? How the f___ are you going to survive in show business if this is an actual obstacle to your dreams?"

CK confirmed last year that the allegations were true, and said in a statement that he was "remorseful" about his actions.