Tottenham manager Mauricio Pochettino has confirmed five of his players have not travelled to Russia for tomorrow's Champions League group game against CSKA Moscow.

Harry Kane, Eric Dier, Mousa Dembele, Danny Rose and Moussa Sissoko have all been left behind in London as Spurs attempt to bounce back from the defeat to Monaco on matchday one.

Kane is sidelined with an ankle injury, the extent of which is not yet known, while Dier and Dembele have been ruled out with hamstring problems after missing Saturday's victory at Middlesbrough.

Rose has not featured for Spurs for a whole month after he picked up a hamstring strain while on international duty with England.

Sissoko made his second Premier League start of the season against Boro but was withdrawn with a head injury in the second half and Spurs have decided not to risk the Frenchman.

"Moussa Sissoko got a head injury in the game against Middlesbrough and he is out,” Pochettino told the club's official website.

“We can’t rule out concussion and so we are treating it this way."

The significant injury list is set to give Pochettino plenty to ponder before selecting his team.

Victor Wanyama and Dele Alli filled in in central midfield at the weekend - and may be asked to do so again - while Ben Davies will be expected to continue to deputise for Rose.

Sissoko's absence is likely to see Erik Lamela recalled to the starting line up and Vincent Janssen will be hopeful he has done enough to continue up front.

Spurs are currently bottom of Group E and require a positive result against Leonid Slutsky's side to get their European campaign back on track.