Republican presidential candidate Donald Trump responded to discrepancies in Ben Carson’s personal biography by saying that the former neurosurgeon has a “pathological disease” that cannot be cured.

“It’s a lot of statements that are under fire,” Trump told CNN’s Jake Tapper. “And I hope Ben’s going to be okay with it… But certainly a lot of people are asking a lot of questions all of the sudden.”

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“It’s a lot of things,” he continued. “You know, when you say hitting your mother over the head with a hammer, when you talk about hitting a friend in the face with a lock, a padlock. And you talk about stabbing someone and it got stopped by a belt buckle.”

Trump observed that “belt buckles don’t really stop stabbings. They turn and twist and things slide off them. It’s pretty luck if that happened.”

“Ben wrote a book, and it’s a tough book because, you know, he talked about he has pathological disease,” the GOP hopeful added. “It’s a serious statement when you say you have pathological disease. Because as I understand it, you can’t really cure it.”

Watch the video below from CNN’s State of the Union, broadcast Nov. 8, 2015.