Rates of new genital wart infection in Australia have plummeted, research shows, in an early positive sign of the success of mass Gardasil vaccinations.

A study taking in patient data from sexual health clinics across the country has shown up to a 60 per cent drop off in new genital wart cases since 2007, when the anti-cancer vaccine was rolled out.

Public health measure a winner ... Sophie Weisz ,14, receives a Gardasil injection.

Gardasil works by preventing the transmission of four strains of the Human papillomavirus (HPV), two of which cause cervical cancer and two which cause genital warts.

Experts say while its effect on cervical cancer rates would take longer to materialise, the vaccine's ability to prevent a less serious though embarrassing problem was now clear.