The FBI is probing a “criminal enterprise” related to Jeffrey Epstein’s suicide at a federal lockup in Manhattan, the head of the Federal Bureau of Prisons testified Tuesday.

The revelation came during Dr. Kathleen Hawk Sawyer’s appearance before the Senate Judiciary Committee, when she was probed about Epstein’s Aug. 10 suicide by hanging at the Metropolitan Correctional Center.

“With a case this high-profile, there’s got to be major malfunction in the system or a criminal enterprise afoot to allow this to happen,” said committee chair Sen. Lindsey Graham (R-SC). “So are you looking at both? Is the FBI looking at both?”

Hawk Sawyer replied, “If the FBI is involved, then they are looking at criminal enterprise, yes.”

Her testimony comes as the two jail guards assigned to watch Epstein the night he died are expected to face federal charges related to falsifying prison records about the financier’s death.

Both guards were working overtime at the time and allegedly failed to check on Epstein every half-hour, as they were required to do.

The city medical examiner later ruled that Epstein committed suicide — though speculation has flowed that he may have been murdered behind bars.

“Do you concur with the opinion that it was a suicide?” asked Graham.

“That was the finding of the coroner, sir,” Hawk Sawyer said.

“Do you have any evidence to suggest otherwise?” the senator continued.

“I do not,” she said, adding that she was barred from speaking about the specifics of Epstein’s case pending the investigation by the FBI and Office of the Inspector General.

Hawk Sawyer served as the BOP’s first female director from 1992 to 2003 and was reappointed to the top post by Attorney General William Barr in August.

During her testimony, she systematically recounted the steps the BOP takes when an inmate is placed under suicide watch, which Epstein had been on a week before his death.