PRIME Minister Julia Gillard has rejected calls for drug decriminalisation, isolating Foreign Minister Bob Carr on the issue.

Responding to the release of a report yesterday that declared that ''tough on drugs'' policies had failed, Ms Gillard said: ''Drugs kill people, they rip families apart, they destroy lives and we want to see less harm done through drug usage.''

Julia Gillard said she was 'not in favour of decriminalisation of any of our drug laws'. Credit:Craig Abraham

While the government would support people to get treatment, she said she was ''not in favour of decriminalisation of any of our drug laws''.

But a spokeswoman for federal Mental Health Minister Mark Butler did not rule out change, saying: ''Any move to soften the stance on illicit drug use in Australia would need to be carefully considered … We will look carefully at this report and the contribution these prominent Australians have made.''