The chef April Bloomfield announced Wednesday that she and the restaurateur Ken Friedman had dissolved their partnership, ending a 14-year run in which they opened and operated some of today’s most influential and popular restaurants. The move comes nearly six months after a New York Times report in which several current and former employees accused him of sexual harassment.

Ms. Bloomfield, who put their Manhattan restaurant the Spotted Pig on the map, made it an international culinary destination and won it a Michelin star, will no longer be involved with the restaurant in any way, a spokeswoman for the chef said.

"Today, I am announcing the end of my partnership with Ken Friedman,” Ms. Bloomfield said in a statement. “There is much hard work ahead, and it begins with taking full leadership of The Hearth & Hound in Los Angeles and Tosca Café in San Francisco. In New York, I remain ​Chef at The Breslin and will begin work on re-concepting The John Dory Oyster Bar.”

The Breslin and the John Dory are in the Ace Hotel, in Midtown; Brad Wilson, president of the Ace Hotel Group, confirmed that Mr. Friedman was out. “April remains at the helm of culinary operations, and we look forward to working with her in this role,” Mr. Wilson said in a statement.