HANOI, Vietnam — An American drone strike on Saturday in a restive province of Pakistan killed Mullah Akhtar Muhammad Mansour, the leader of the Afghan Taliban, the White House confirmed on Monday.

Calling the death “an important milestone,” President Obama said in a statement, released just as he was meeting with top officials in Vietnam, that the United States had “removed the leader of an organization that has continued to plot against and unleash attacks on American and coalition forces.”

Image Mullah Akhtar Muhammad Mansour, in an undated photo. Credit... Reuters

“Mansour rejected efforts by the Afghan government to seriously engage in peace talks and end the violence that has taken the lives of countless innocent Afghan men, women and children,” Mr. Obama continued in the statement. “The Taliban should seize the opportunity to pursue the only real path for ending this long conflict — joining the Afghan government in a reconciliation process that leads to lasting peace and stability.”