The Pharmaceutical sector had 46.9% growth which is the second biggest percentage increase in NSV in Ireland between the years 2013 – 2016. The most significant increase in Net Selling Value was in the Pharmaceutical sector. The value of Basic pharmaceutical products and preparations increased by 18.2% from €36.1 billion in 2014 to €42.6 billion in 2015. The global drug delivery technology market is projected to reach USD 1,669.40 Billion by 2021 from USD 1,179.20 Billion in 2016, at a CAGR of 7.2% during the forecast period. This market is segmented based on route of administration, facility of use, and region. The global nanotechnology drug delivery market was valued at US$ 41,062.5 Mn in 2014 and is projected to reach US$ 118,527.2 Mn by 2023, expanding at a CAGR of 12.5% from 2015 to 2023.

There is a strong market for nanopharmaceutics and drug delivery in Europe. The pharmaceutical business in Ireland is profoundly best in class, incorporating the most recent innovation, cutting edge equipment and strict quality control methodology. Ireland's pharmaceutical industry offers an extensive variety of items and services, from research and development for new medicines to the manufacturing and marketing of new medicines for humans and animals. Around 120 abroad organizations have plants in Ireland including 9 of the 10 biggest pharmaceutical organizations on the planet. The pharmaceutical business is generally new to the Irish economy. A large portion of the organizations working around there have just had nearness in Ireland since the 1960s.

Nanomedicine and drug delivery can address one of the greatest difficulties in the post-genomic time of the 21st century – making the essential associations amongst Academics and industry professional.

It is forecasted that the total market size of Nanomedicine and Advanced Drug Delivery would be $755.3 billion with a 60/40 split between nanomedicine and advanced drug delivery respectively, although developing new targeted delivery mechanisms may allow more value to be created for companies and entrepreneurs.

SESSIONS/TRACKS

Track 01: Cancer and Nanotechnology

Nanotechnology can possibly build the selectivity and power of concoction, physical, and organic methodologies for inspiring disease cell demise while limiting collateral toxicity to non-malignant cells. Materials on the nanoscale are progressively being focused to malignancy cells with extraordinary specificity through both active and passive targeting. Customary chemotherapeutics have some genuine reactions including harm of the immune system and other organs with rapidly proliferating cells due to nonspecific targeting, absence of solvency, and failure to enter the centre of the tumours bringing about weakened treatment with decreased dosage and with low survival rate. Nanotechnology can provide rapid and sensitive detection of cancer-related targets, enabling scientists to detect molecular changes even when they occur only in a small percentage of cells. Nanotechnology also has the potential to generate unique and highly effective theraputic agents.

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Track 02: Nanomedicine

Nanomedicine is a branch of medicine that uses the Nanotechnology for the prevention and treatment of disease in the human body. This evolving discipline has the potential to dramatically change medical science. Nanomedicine fuses the usage of nanoscale materials, for instance, biocompatible nanoparticles and nanorobots, for examination, conveyance, distinguishing or incitation purposes in a living structure. Current issues for nanomedicine incorporate understanding the issues related to lethality and environmental impact of nanoscale materials , Preparation of nano-prescriptions and its application. Research are being completed give a wide audit of magnetic nanoparticle, Silver nanoparticles, Gold nanoparticles explore with a special focus on the synthesis, functionalization and medicinal uses of these particles.

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Track 03: Design of Nanodrugs

Nanodrugs sensational advances in nanotechnology and nanoscience have been joined by energizing advancement in de novo design of nano sized drugs. Nanoparticles with their vast space of structural amenability and phenomenal mechanical and electrical properties have turned out to be perfect contender for high viability nanomedicines in both diagnostics and therapeutics. The restorative nanomedicines can be additionally sorted into nanoparticle drug delivery for regular medications and nanodrugs and nanobots with coordinate curing of target illnesses. Nano molecule are characterized into three general classifications One dimension, two dimension , and three dimension nanoparticles and each have an different fabrication techniques. Difficulties in design of nano drugs incorporate system of drug loading and discharge, safety issues and its limitations and so on.

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Track 04: Drug Targeting and Design

The main objective in drug design is to foresee whether a given particle will bind to a target and if so how unequivocally. Molecular mechanics or molecular dynamics are regularly used to predict the conformation of the little particle and to model conformational changes in the biological targets that may happen when the little molecules ties to it. The remedial reaction of a drug relies on the cooperation of drug molecules with cell on cell membrane related biological events at receptor sites in concentration dependent manner.

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Track 05: Novel Drug Delivery Systems

Drug delivery is the way toward managing the drug or pharmaceutical product, so as to accomplish sought therapeutic impact. The strategy by drug delivered is critical, as it has noteworthy impact on its efficacy. Novel drug delivery system (NDDS) includes consolidating polymer science, pharmaceutics and molecular biology. Novel drug delivery systems are outlined in view of physical and biochemical mechanisms. Physical mechanisms or controlled drug delivery system incorporates dissolution, osmosis, and diffusion and so on. Biochemical mechanism incorporates gene therapy, liposomes, nanoparticles, monoclonal antibodies, microemulsions and so forth some example of drug delivery system (DDS) are Transmucosal, Sonophoresis , Lymphoid, Insitu, Micelle, Emulgel, and Hydrogel drug delivery system (DDS).

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Track 06: Routes of Drug Administration

Route of administration in medicine is the path by which a drug is taken into the body. Routes of administration are generally classified by the location at which the substance is applied. Routes of drug administration is aimed at developing novel routes to minimize side effects form common routes by which a drug is brought into contact with the body.

The drug delivery technology market is expected to reach USD 1,504.7 Billion by 2020 from USD 1,048.1 Billion in 2015, growing at a CAGR of 7.5% from 2015 to 2020. Factors such as rising prevalence of chronic diseases, growth of the biologics market, new product launches, and drug innovation and technological advancements are driving the growth of this market. On the other hand, patent expiry and patent cliff, increase in the injuries and side effects are hindering the growth of this market.

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Track 07: Pharmaceutical Nanotechnology

Nanotechnology has turned into a fundamental component of pharmaceutical sciences and finds numerous applications in pharmaceutical formulation design and drug delivery systems in upgrading helpful execution of medications. A significant number of the current "nano" medicate conveyance frameworks are family of regular measurements shapes like nanosuspensions, nanoemulsions, and nanomicelles Pharmaceutical Nanotechnology manages rising new innovations for creating redid answers for drug delivery systems. The medication conveyance framework emphatically impacts the rate of ingestion, dispersion, digestion, and discharge of the medication or other related compound substances in the body. Notwithstanding this the medication conveyance framework additionally enables the medication to tie to its objective receptor and impact that receptor's signaling and activity.

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Track 08: Nanomaterials for Drug Delivery

Nanomaterials vary fundamentally from different materials because of the accompanying two noteworthy primary factors: the expanded surface zone and quantum impacts. These elements can improve properties, for example, reactivity, quality, electrical characteristics and in vivo behaviour. Nanotechnology and nanoscience are generally observed as having an awesome potential to bring advantages to numerous ranges of research and applications. The utilization of nanotechnology in the field of medicinal services has gone under awesome consideration as of late. There are numerous medications today that take a considerable measure of time and are additionally exceptionally costly. Utilizing nanotechnology, snappier and considerably less expensive medications can be created , the real difficulties in these medication delivery is the choice of sheltered and biocompatible nanocarriers , mechanism for drug delivery, solubilisation procedures.

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Track 09: Nanotechnology and Biomedical Applications

The applications of technology in drugs and biomedical engineering are huge and spans areas like implant and tissue engineering, diagnosis , Bio-Sensors , nano-probes and medical aid .There is another viewpoint for utilizing technology. Ordinarily, medicine run through the complete body before they achieve the sickness influenced region. Utilizing nanotechnology, the medication can be focused to an exact area which would make the medication considerably more successful and decrease the odds of conceivable symptoms. Nanotechnology also finds its application in dentistry , biosystems , respiratory diseases , Genetic nanomedicine etc.

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Track 10: Personalized Nanomedicine

Personalized medicine means to individualize chemotherapeutic intercessions on the basis of ex vivo and in vivo data on patient-and disease-specific characteristics. By noninvasively picturing how well picture guided nanomedicines-that is, sub-micrometer sized drug delivery systems containing the drugs and imaging operators inside a solitary formulation, and intended to all the more particularly convey drugs particles to pathologic destinations gather at the target site, patients prone to react to nanomedicine-based therapeutic interventions might be preselected. What's more, by longitudinally observing how well patients react to nanomedicine-based therapeutic mediations, tranquilize measurements and treatment protocols can be individualized and improved amid development.

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Track 11: Drug Delivery Research

Drug delivery describes the tactic and approach to delivering medicine or and different xenobiotics to their site of action inside an organism, with the goal of achieving a therapeutic outcome. problems with pharmacodynamics and pharmacokinetics area necessary concerns for drug delivery. Designing and developing novel drug delivery systems, with attention on their application to sickness conditions. diagnosis and clinical knowledge associated with drug delivery systems. Drug distribution, pharmacokinetics , clearance, with drug delivery systems as compared to ancient dosing to demonstrate helpful outcomes. short and long biocompatibility of drug delivery systems, host response. Biomaterials with growth factors for stem-cell differentiation in regenerative medication and tissue engineering. Devices for drug delivery and drug/device combination product.

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Track 12: Drug Delivery Equipment’s and Machinery

Equipment and Machinery for Drug Delivery incorporates Laboratory equipment's, Analytical equipment's, Auto Injectors, Semi-Automatic, R&D Equipment, Large volume Production Machineries and Drug Delivery Pilot hardware's and so forth this field is progressing at a colossal pace.

The drug delivery technology market is expected to reach USD 1,504.7 Billion by 2020 from USD 1,048.1 Billion in 2015, growing at a CAGR of 7.5% from 2015 to 2020. Factors such as rising prevalence of chronic diseases, growth of the biologics market, new product launches, and drug innovation and technological advancements are driving the growth of this market. On the other hand, patent expiry and patent cliff, increase in the injuries and side effects are hindering the growth of this market.

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Track 13: Smart Drug Delivery Technology

With the uncommon advances of biomedical nanotechnology amid the previous couple of decades, customary drug delivery systems (DDSs) have been included into smart DDSs with boosts responsive characteristics. The smart drug delivery system is utilized for conveying drugs to the host. Organic data identified by biological sensors is examined and the drug delivery system is impelled to convey the drugs in view of the data. The framework uses MEMS or NEMS innovation based drugs pumps, micro pumps, miniaturized needles, micro-osmotic pumps, and nano-pumps. MEMS based drug delivery system give improved medication treatment which permits precise dosing with more viability and adequacy. The utilization of MEMS for drug delivery through biocapsules, microneedles, and micropumps offers a less obtrusive drug therapy and enhances the quality life of the patients. It likewise incorporates sensors or communication frameworks to remotely actuate or control the pumps.

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Track 14: Regenerative Medicine and Tissue Engineering

Regenerative medicines and tissues engineering, are the branches of biomedical engineering. Tissue engineering and regenerative medicines are involved with the replacement or regeneration of cells, tissues or organs to revive traditional biological function. Tissue engineering could be a aggressive space of analysis that aims to make tissue equivalents of blood vessels, heart muscular tissue, nerves, cartilage, bone, and alternative organs for replacement of tissue either broken through sickness or trauma. As an knowledge domain field, principles from biological, chemical, electrical, materials science, and engineering are used in analysis and development.

The global Regenerative medicine market is expected to reach USD 38.70 Billion by 2021 from USD 13.41 Billion in 2016 at a CAGR of 23.6% from 2016 to 2021. The major factor driving the growth of this market, are government and private funding to support the development of regenerative medicine, rising prevalence of chronic diseases and genetic disorders, increase in global healthcare expenditure, and rapid growth in the aging population.

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Track 15: Regulatory Aspects Towards Approval of Nanomedicine

Biomaterials and nanotechnology are among the most promising tools to conquer drawbacks which were mostly associated with non-specific effects of customary therapeutic approaches. Nonetheless, the extensive use of nanomedicines requests a significant learning and portrayal of these mind boggling items. Their properties should be widely comprehended to keep away from unpredicted consequences for patients, for example potential immune reactivity. Research strategy and organizations together have been uniting researchers, controllers, industry, and, more frequently in recent years, patient representatives and patient support establishments. To effectively upgrade the advancement of new technology , enhanced systems for look into based corporate associations, more coordinated research devices managing suitable translational necessities going for clinical improvement, and proactive administrative arrangements are fundamental sooner rather than later.

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Track 16: Vaccine Design and Delivery Technology

Vaccines have long been used to fight against infectious disease; however the last decade has witnessed a revolution in the approach to vaccine design and development. Immunization Drug Delivery are multidisciplinary scientific field that is right now experiencing quick improvement. Latest vaccines that are steady, sparing, require less dosages and can be controlled utilizing needle free frameworks are an overall need. A perfect hypothetical vaccines may not be cogent unless formulated and delivered relevantly. Critical to the accomplishment of a vaccine is the conveyance technique that will be utilized. Currently, various techniques involving DNA vaccines, adjuvants, microparticles and transgenic plants are being developed and evaluated , there has been an increasing emphasis in the field of vaccines on the neeed for improved safety along with improved efficacy against particularly insidious pathogens. More recently , the threats of a bio-terrorist attacks has been added an even sense of urgency to these efforts.

The drug delivery technology market is expected to reach USD 1,504.7 Billion by 2020 from USD 1,048.1 Billion in 2015, growing at a CAGR of 7.5% from 2015 to 2020

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Track 17: Drug Delivery and Device Development

The use of therapeutic devices and different strategies of drug delivery continues to evolve and increase. Drug delivery devices are specialised tools for the delivery of a drug or therapeutic agent via a selected route of administration. Such devices are used as a part of one or a lot of medical treatments .There are many medical devices designed for drug delivery through the respiratory organ and nasal routes. These routes are of interest for native delivery, as in asthma attack, however additionally for speedy delivery of medication to the system circulation and direct delivery to the central nervous system.

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Track 18: Recent Advances in Drug Delivery

Simplicity of drug administration, safety, affordability and effectiveness are the most important issues in pharmacotherapy resulting in exploration of higher drug delivery systems. Drug targeting to specific organs and tissues has become one in all the essential endeavors of the century since the utilization of drugs in standard dosage forms typically involves difficulties in achieving the target site at the acceptable dose during or after a definite time. Consequently, the look for new drug delivery approaches and new modes of action represent one of the frontier research areas. New drug delivery systems incorporates lipidic, proteic and polymeric technologies to produce new sustained drug delivery with higher body distribution, drug protection from harsh external surroundings and avoidance of drug clearance. several of these technologies have reached the market thus proving the advantages of those new carriers.

Track 19: Major Challenges in Drug Delivery

There are numerous biochemical boundaries that can upset effective drug delivery, Major Challenges in Drug Delivery Systems incorporates delivery of ineffectively dissolvable drugs and bioavailability obstacles for inadequately solvent clinical applicants, protein drug delivery, paediatric and geriatric drug delivery. Self-emulsifying drug delivery system (SEDDS) have unparalleled potential in enhancing oral bioavailability of poorly water-soluble drugs. There are a few Novel methodologies in the delivery, Overcoming bioavailability obstacles and Rationale formulation design of poorly soluble drugs. There is an expanding interest for for effective and, ideally, non-invasive drug-delivery methods.

Today, biopharmaceuticals generate global revenues of $163 billion, making up about 20 percent of the pharma market. It’s by far the fastest-growing part of the industry: biopharma’s current annual growth rate of more than 8 percent is double that of conventional pharma, and growth is expected to continue at that rate for the foreseeable future.

Track 20: Drug Delivery Companies and Markets

Increase in chronic diseases, increasing demand for biologics, advancement of technology , and new product launches are one of the key factors driving the evolution of the drug delivery technology market. moreover, self-administration and residential care and increasing demand for biosimilars and generic medicine supply vital growth opportunities for player operative within the market. On the other hand, risk of needle-stick injuries and side effects of medication might restraint the expansion of the market.

The global revenue for advanced drug delivery systems is estimated to be $151.3 billion in 2013. In 2018, revenues are estimated to reach nearly $173.8 billion, demonstrating a compound annual growth rate (CAGR) of 2.8%.

Prominent players in the drug delivery technology market include Johnson & Johnson, Inc. (U.S.), F. Hoffman-La Roche (Switzerland), Merck & Co., Inc. (U.S.), Bayer AG (Germany), Pfizer, Inc. (U.S.), Novartis AG (Switzerland), 3M Company (U.S.), Becton, Dickinson and Company (U.S.), GlaxoSmithKline plc, (U.K.), Sanofi (France), and Antares Pharma, Inc. (U.S.).

Track 21: Nano Pharmaceutical Industry and Market

Nanopharmaceuticals represent an emerging field and offer the capacity to distinguish sicknesses at considerably prior stages and the diagnostic applications could expand upon conventional techniques utilizing nanoparticles, Nano-empowered medical items have had their effect on the areas, for example, cancer, CNS diseases, cardiovascular diseases, and infection control. While nano-upgraded drug delivery items are now a business reality, more progressed nanotech-based medical gadgets are still being developed, although some are at the clinical testing stage. A large portion of the money being spent on the more extensive field of nanotechnology R&D originates from government and built up enterprises. In the nanomedicine field, pharmaceutical and specialist organizations are at the front line of research into the therapeutic uses of nanotechnology.

The global nanomedicine market reached $43.2 billion in 2010 and $50.1 billion in 2011. The market is expected to grow to $107.6 billion by 2016 and is expected to reach 130bn in 2019 at a compound annual growth rate (CAGR) of 14.1.

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