Police said it remains unclear if the fire started in the casino in the lower floors or in an area of the hotel that was under renovation.

A fire that hit a hotel and casino complex in the Philippine capital on Sunday killed least three employees, trapped two others and forced the evacuation of more than 300 guests, some by helicopter, officials said.

Police said it remains unclear if the fire at the Manila Pavilion Hotel and Casino, which was still raging after seven hours, started in the casino in the lower floors or in an area of the hotel that was under renovation.

TV footage showed dark grey smoke billowing from the first and second floors of the hotel as rescuers brought people out of the building.

Two firemen who ran out of oxygen while searching for trapped employees are lowered to safety following a fire that engulfs the Manila Pavilion Hotel and Casino, in Manila, Philippines on Sunday. | Photo Credit: AP

Johnny Yu, who heads Manila’s disaster-response agency, said that at least six other people were overwhelmed by heavy smoke and brought to a hospital. Among the dead were two security guards and a treasury officer, he said.

Mr. Yu initially said at least four people died in the fire, but other officials later said that one of those who was feared to have died was revived by doctors at a hospital and was in critical condition.

“The smoke is very heavy and, second, there’s the wind that we’re trying to overcome,” Mr. Yu said. “Our firefighters are having a lot of difficulty.”

At least 19 people were unaccounted for, but Mr. Yu said that only two, both security camera operators, were confirmed to have been trapped in the hotel and rescuers were trying to reach them.

Police and firefighters blocked off the areas around the hotel, which lies in the heart of Manila’s tourist district, to allow dozens of firetrucks to approach and help fight the blaze.