WASHINGTON — The United States on Tuesday carried out its first drone strike in Pakistan’s restive tribal areas in nearly two months, ending a pause that was intended to avoid worsening relations between the countries after an American airstrike in November killed two dozen Pakistani troops.

Missiles fired from a remotely piloted aircraft struck a house outside of Miram Shah in the North Waziristan tribal area, killing at least three militants, Reuters reported, citing a local intelligence official.

Officials in Washington confirmed the strike but, as is customary with missile attacks from drones operated by the Central Intelligence Agency, they would not provide any details.

The C.I.A. last conducted a drone strike in Pakistan on Nov. 16, 10 days before the attack that killed the Pakistani troops in two remote outposts along the border with Afghanistan.