Colts at Rams, 4:05 p.m. Sunday, CBS

INDIANAPOLIS – It’s not football season if we’re not talking about the Indianapolis Colts’ offensive line.

The unit is front and center again, with another shakeup of the starting lineup coming in Sunday’s season opener — just like every single season since 2012.

That’s not a trend. That’s an event you set your watch to.

Today’s edition of “As the Colts Offensive Line Turns” includes changes so dramatic reporters thought maybe there were errors in the depth chart distributed by the team earlier this week.

Denzelle Good is moving from backup guard to starter at right tackle. Jeremy Vujnovich, who had a strong preseason and seemed destined to start at right tackle, is moving to left guard. Jack Mewhort remains at right guard and undrafted rookie Deyshawn Bond, after a strong preseason, gets the start at center in place of injured Ryan Kelly.

It's reached the point that even the linemen themselves know to be ready for anything and have come to handle these predictable ups and downs with a sense of humor.

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If Mewhort starts at right guard, it will mark the third-consecutive season he’s opened the year at a different position.

Are you trying them all, he was asked?

“Sure, why not?” Mewhort cracked.

But the stakes here are no laughing matter. The Colts seemed to take a few forward steps with their offensive line in 2016. But injured quarterback Andrew Luck’s frequent hits over the years will never truly become a thing of the past until this unit proves it can be counted on.

And on Sunday, against the talented Los Angeles Rams defense (even without contract holdout Aaron Donald), they’ll be trotting out a group that isn’t exactly a list of household names.

There’s Bond, who is making his regular-season debut. Give him credit for ably accepting the challenge of replacing Kelly with some rather impressive play through the preseason. That’s not to say you should presume he’ll have a flawless performance against Robert Quinn, Michael Brockers and company.

But don’t underestimate the importance of the confidence he gained from the preseason.

“As an undrafted guy, coming in I didn’t know what to expect,” said Bond, who played at Warren Central High School. “It really helped me get my feet under me, just seeing how my teammates and my coaches believed in me really helped me push myself and believe I could do it and I wanted to prove to these guys that I could do it.

“A lot of guys are drafted, a lot of guys are undrafted. It doesn’t matter. You have a role on the team and my role is to come out and give it my all.”

Then there’s Good, who we thought would be a guard this season, but now has turned his complete focus to the vacant right tackle spot. The 2015 seventh-round draft choice seems rejuvenated after battling injuries while playing guard last season. Now, he’s back where he believes he belongs and where he's enjoyed more success.

“I feel more natural at tackle,” Good said. “I feel like I have good athleticism and I think it just gives me space to make the right decisions. At guard, everything is right there and it’s real quick. It’s a lot easier for me when I’m in space to stay in front of someone.”

This is a new-and-improved version of Good, one who is 20 pounds lighter at 335. He took upon himself to lose the weight entering training camp — the Colts advised him to report at last year’s weight of 355 — and Good said the decision is paying off.

“I just took pride in myself,” he said. “I came back feeling great. I don’t have any (injuries) bothering me. … I feel a lot quicker. I feel less stress after practice and not as sore through the week. I feel great.”

Vujnovich is your quintessential journeyman, bouncing between practice squads and active rosters since 2014 after playing at Louisiana College. General Manager Chris Ballard said this week that Vujnovich’s emergence during the preseason — though at right tackle — was “a surprise.” And coaches will give him a chance to keep it going on Sunday at the Los Angeles Coliseum.

After spending four weeks on the Colts’ active roster last season as an emergency option, Vujnovich is accustomed to being ready for anything.

“I go home and look at the playbook and I have to know guard, tackle, whatever,” he said. “So, you really start to understand the whole scheme and you understand each position.”'

If you're wondering about Joe Haeg's absence from the starting lineup, it's unclear whether it's related more to performance or health. He's been in and out of the lineup during the preseason with injuries, and perhaps could return if fully healthy.

Somehow, in spite of his team fielding an offensive line that’s less than ideal, coach Chuck Pagano smiled his way through Wednesday’s news conference. He was asked whether addressing offensive line questions has gotten old. He offered an unpredictable response.

“I think we’re fine,” he said. “I woke up this morning and I couldn’t wait to get to work.

“I’ve never felt better about my offensive line. You guys can write it and put on the record and hold (me) to it. There’s going to be some mistakes made, but we’re going to dress seven, maybe eight guys, and all those guys will be prepared to play good football. … You guys might be losing sleep at night, but we need our rest. So, we’re not.”

Maybe Pagano really believes that. Or, perhaps he’s just tapping into the power of positive thinking.

Either way, he knows how to handle these questions.

Because it’s football season. So, naturally, we’re talking about the Colts’ offensive line.