Senior NSW Liberals have conceded the Berejiklian government is "getting it wrong" on key issues and is facing the likelihood of being unable to retain its majority at next year's election.

As MPs were coming to terms with the spectacular loss of one of the Liberal Party's safest seats in the Wagga Wagga byelection, senior party figures warned that the Coalition was in "certain danger".

"We lost Orange when we didn't expect it, we lost Wagga when we didn't expect it and now we only have six seats before we are in minority. I think it is almost a certainty," one senior minister said.

"This train wreck in Wagga will no doubt panic MPs, and I would expect some will start to jump ship as they face the possibility of being in opposition."