Gentrification has set its sights on another great American cultural center — this time it's at Seattle's legendary Showbox.

Opened in 1939, Showbox hosted some of the greatest jazz, pop and rock artists of the 20th century. Perhaps most consequentially, Showbox was a key venue for Seattle's grunge scene as the movement simmered to a boil in the region in the late-'80s and early-'90s.

Now the club is set to be all or mostly torn down and replaced with a 44-story high rise.

Chris Cornell's daughter Lily Cornell Silver, who grew up in Seattle and has promoted shows at the venue on her social media, recently decried the news via an Instagram Story post.

Guns N' Roses bassist Duff McKagan is urging his Twitter followers to sign a petition to stop the wrecking ball and protect the Showbox as a historical landmark.

"This Showbox closing cannot stand!" McKagan wrote. "This place was musically flavored what Seattle IS at its core. Progress is great and all, but not at the cost of the soul of the city."