Marcus Rashford is a doubt for England's Euro 2020 clash against Czech Republic, opening up the exciting prospect of Jadon Sancho making his first competitive international start.

Manchester United forward Rashford missed Tuesday's training session at St George's Park with an ankle injury and could miss Friday's clash at Wembley.

Rashford's movement in the joint has been restricted since the 0-0 draw against Liverpool on February 24.

Jadon Sancho is in contention to make his first competitive international start on Friday

And if Rashford fails to prove his fitness ahead of the qualifier against the Czech Republic, then Borussia Dortmund sensation Sancho will be a strong contender to replace the Old Trafford star alongside Harry Kane and Raheem Sterling in attack.

Sancho has three caps for England - including one start against the USA in November.

But if the 18-year-old impresses Gareth Southgate enough in training to start against the Czechs, it will be his first competitive start.

Dele Alli will also be an option for the role vacated by Rashford. Callum Hudson-Odoi is unlikely to start given he was only drafted into the squad following a string of withdrawals.

England captain Kane said: 'He has no fear. We had a little sudden-death penalty shoot-out and he chipped his one down the middle.

Gareth Southgate is set to call on the youngster for Euro 2020 opener with Czech Republic

Marcus Rashford missed training on Tuesday and may sit out on Friday due to an ankle injury

'That takes a bit of bottle, especially at his age, but it shows he is enjoying it and that is what we want. We want players to enjoy it and express themselves in any part of the game or training and he certainly has done that today. '

Elsewhere, Southgate is facing a key selection dilemma following the injury withdrawal of John Stones.

The Manchester City defender's ability to pass accurately through the lines from defence into attacking areas has been a key feature of England's play under Southgate.

The issue has been discussed by Southgate and his staff this week. With Stones unavailable, there is a concern the team will lose that incisiveness from the back that became a feature of their success in last summer's World Cup.

Harry Maguire is likely to start in a back-four, with Southgate, who held one-on-one meetings with his players at St George's Park on Monday night, understood to be leaning towards playing Michael Keane alongside the Leicester star. Burnley's James Tarkowski is another option.