Missy Elliott has reportedly lost over 70 pounds.

And on Thursday, the 43-year-old rapper displayed her dramatically thinner figure as she performed at Alexander Wang’s H&M Collection launch in New York City.

Missy shared a snap to Instagram, showing off her svelte frame, following a years long health programme to bring her weight down as she continues to battle a rare disease that attacks the thyroid.

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Quite the change: Missy shared a snap to Instagram on Thursday (L) showing off her svelte frame, which was dramatically different from 2010 (R)

The Why Stop Now singer, captioned her social media picture: 'Just got off stage thanks @ALEXANDERWANGNY and @hmusa for having me perform I enjoyed'.

Missy looked sporty as she wore a Nike hooded jumper and a snap back cap with the words 'You Can't Workout With Us' as she stood with her hands on her hips.

Back in 2011 she revealed her struggle with Graves' Disease.

Keeping it off: The rapper, pictured performing on Thursday, has been on a health programme since being diagnosed with Graves' Disease in 2008

The star told People magazine at the time that she was diagnosed with the autoimmune disease - which affects the thyroid - back in 2008.

And the illness has been so debilitating that it even made it difficult for Missy to complete everyday tasks.

'I couldn't write because my nervous system was so bad - I couldn't even use a pen,' she says.

Battle: In 2011 the now 43-year-old revealed her struggle with the rare disease which attacks the thyroid

The singer initially realised something was wrong when she was driving and her leg started 'jumping'.

'I couldn't keep the brake down and almost crashed,' she recalls.

The star also suffered severe mood swings, dizzy spells and hair loss; ending up undergoing radiation treatment which improved her condition, along with medication.

Slimming down: Missy pictured in 1998 has been slowly losing the weight over the years

There is no cure for Graves' disease, but Missy's condition has improved over the past year.

'I'm 30 pounds lighter because I've been exercising,' she reveals. 'My thyroid is functioning, so I haven't had to take medication in about nine months. [But] you live with it for the rest of your life.'