Recently, television has given worthwhile, prosaic voices a vehicle. Tig Notaro is a terribly funny, wry voice that has been popping up all over television for years now on things like The Sarah Silverman Program, Comedy Bang Bang, and Transparent, not to mention producing some glowing stand-up specials like, Boyish Girl Interrupted and Knock Knock, It’s Tig Notaro.

Notaro is also someone who has undergone an extreme amount of hardship over the past few years, undergoing tragedies like the death of family member and a cancer diagnosis. Notaro channels these difficult years along with her trademark sardonic wit into a soothing show that distinctly feels evocative of whom she is. One Mississippi is a great insight into Notaro’s mind, as well as another stepping-stone in this comedian’s career. With the series set to premiere on Amazon, we had the opportunity to pick Tig’s brain regarding the fundamentals of her new show, mixing comedy with tragedy, and why her hometown is such a crucial part of the series.

DEN OF GEEK: One Mississippi does a really great job doing this call and response where your character is interacting with her past. What do you like getting from that juxtaposition between past and present?

TIG NOTARO: Well I feel like it fills in a lot of blanks. There are also the moments where it’s not something from my past. They’re just these moments that I’ve created with my mother that never happened. All of that comes from the moment where I walked in the door from taking my mother off life support. I mean, it’s not all from that, but those moments that I’ve fabricated with my mother are when I walked into the house and she wasn’t there to greet me, and she always had been at every age of my life, no matter what time it was. She would always greet me. I guess it’s just a long goodbye where I’m creating moments to continue to say bye to her.