In a Smithsonian study, the below movie scene elicited a bigger sad reaction from viewers than any other.

It's used as a litmus test in psychological exams to determine when a subject is affected by upsetting content.

It's the emotional climax of the 1979 drama "The Champ," starring a pint-sized Ricky Schroeder.

Video below—but prepare to be depressed for the rest of the day.