I wasn't sure how to interpret this until I realized the Tower represents the Tower of Babel.

Doomed quest to attain (through godless mastery of the material world) some form of ascension/divinity/freedom-from-imperfection that is suddenly and violently dismantled just as it nears completion, setting the scene for a chaotic new beginning in its passing.

Jack was their tower from human to BIOTIC GOD and she came down on them hard. Nice.