Joe Scarborough on Wednesday detailed his break up with the Republican Party, saying the "heartless" ObamaCare repeal and replace bill was the final straw for him.

“I think maybe the last straw for me actually wasn’t Russia, it was the healthcare bill,” the co-host of MSNBC's "Morning Joe" said during an event at the National Archives in Washington, D.C., on Wednesday night. “That kicks 25 million people off of their health insurance, and then they turn around and give tax cuts to the richest one percent of America.

"I think the healthcare bill is heartless, I think the way they did it is shameful, and they did it without any transparency, and at the end of the day I just couldn’t defend them anymore, after 20, 25 years,” he added.

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The event was hosted by the Harvard Kennedy School's Institute of Politics. Scarborough and his "Morning Joe" co-host Mika Brzezinski are launching a fellowship at the institute and were interviewed by David Rubenstein, co-founder and co-CEO of the Carlyle Group and chairman of the Campaign for the Harvard Kennedy School.

Scarborough's comments came after he announced Tuesday night during the "Late Show with Stephen Colbert" that he was leaving the Republican Party after decades. Scarborough was a House representative from Florida from 1995 to 2001.

“What bothered me the most was that the Republican Party and its leaders came up with so many reasons why they didn’t support Donald Trump Donald John TrumpUS reimposes UN sanctions on Iran amid increasing tensions Jeff Flake: Republicans 'should hold the same position' on SCOTUS vacancy as 2016 Trump supporters chant 'Fill that seat' at North Carolina rally MORE, but I never heard that it was because he was a racist,” Scarborough said Wednesday night. “That he was basically a political bottom-feeder, that he was trying to appeal to the worst instincts in the Republican Party.”

He also slammed the GOP Congress' agenda.

“I’m a small government — uh, I guess conservative. I’m afraid to even use that word now,” he told the audience. “There is nothing conservative about this party."

He told the audience he had little faith the GOP could get back on track.

“I think the Republican Party is in for some very, very tough years ahead," he said.

“I don’t know if they survive Donald Trump. I think George W. Bush, when he privately told people that he might be the last Republican president elected, I think he may have been right. Donald Trump is a lifelong Democrat who became a Republican when he discovered birtherism.”

Scarborough and Brzezinski announced in May that the two are engaged.

The pair told the audience they were considering a Nantucket wedding in the spring.

The two have been tough critics of Trump on their show.

The president went after Brzezinski earlier this month on Twitter saying she was "bleeding badly from a face-lift" when he saw her after New Year's.

Scarborough fired back and said the White House had threatened to run a tabloid story against them if they didn't apologize to the president for their criticism.