Former governor William Cox will undertake the first five yearly review of Tasmania's Integrity Commission.

Attorney-General Vanessa Goodwin said the review, required under law, would consider the operation of the commission and its act.

She said it would also look at "other matters relevant to improving ethical conduct and public confidence in authorities".

The corruption watchdog has had a testy relationship with the State Government in recent years over budget cuts as well as a Government submission recommending axing its investigative and law enforcement functions.

Its chief executive Diane Merryfull quit last month, three years into a five-year term.

She criticised Tasmania's senior public servants for having "entrenched positions" and a strong resistance to change.

She conducted a damning investigation into nepotism within Tasmania's hospital system, which had widespread fallout for those involved.

Those reports were not always well received, with the commissioner coming under criticism from the Government, the public service and the union movement.

She feuded publicly with the Hodgman Government over budget cuts and claimed a lack of resources would hamper the commission's ability to investigate new complaints

In August, the chief commissioner Murray Kellam stood down after a parting shot at the Government, accusing it of complacency in tackling corruption.

The Joint Standing Committee on Integrity completed a review of the commission earlier this year.

The State Opposition claims the Government does not support the commission, but in announcing the five-year review Ms Goodwin said "...the Integrity Commission should continue to play an investigative role after the five year-review".

William Cox is a former chief justice of the Supreme Court.

He will begin the review in February and it is expected to be finished by the end of the year.