Fox's Charles Krauthammer characterized Attorney General Jeff Sessions Jefferson (Jeff) Beauregard SessionsGOP set to release controversial Biden report Trump's policies on refugees are as simple as ABCs Ocasio-Cortez, Velázquez call for convention to decide Puerto Rico status MORE as "a dead man walking" after being repeatedly attacked by President Trump in interviews and on social media over the past week.

“I think the bottom line is he wants him to resign. On Friday, I said that Sessions was a wounded man walking. Last night on ‘Special Report’ I said he was a dangerous, wounded man walking. Tonight, he is a dead man walking," said Krauthammer to host Martha MacCallum on "The Story."

"There is no way that a president can humiliate a Cabinet member, a strong supporter from the beginning, in the way that Trump has done, just piling it on and expect that this relationship is going to last," the syndicated columnist continued.

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"He’ll either be fired, or it could be that he has decided that he is going to dig in his heels and some kind of resistance — he’ll stay in office no matter what. But this cannot last."

Krauthammer also warned that Trump's treatment of Sessions "has alienated many conservatives" and could endanger the loyalty of his base.

"The danger to Trump is that Sessions represents sort of the policy side, the philosophical side, the conservative side of what Trump represented, and he held a lot of that coalition brought back to Trump," Krauthammer said. "And by getting rid Sessions, he has alienated many conservatives. There are some who are already complaining. And that could be dangerous for Trump because what sustains them is the power and the loyalty of his base.”

MacCallum observed that "it appears that [Trump] really wants to get rid of [special counsel] Robert Mueller. And he blames Sessions for stepping aside and provoking that in the first place, certainly Comey as well."

"If that is the grand strategy, this is about as clumsy and self-destructive way of executing that as there is," Krauthammer replied. "And I think we will see that play out."

The friction between Trump and Sessions comes after a New York Times interview last week in which the president said that he would never have chosen Sessions to be his attorney general if he had known he would recuse himself from the Russia investigation due to a conflict of interest.

“Sessions should have never recused himself, and if he was going to recuse himself, he should have told me before he took the job, and I would have picked somebody else,” Trump said.

Trump appeared to imply Sessions was disloyal during a speech to the Boy Scouts of America at its 2017 Jamboree in West Virginia on Monday.

“As the Scout law says, a scout is trustworthy, loyal — we could use some more loyalty, I will tell you that,” the president said.

Former federal prosecutor and New York City Mayor Rudy Giuliani (R) and Sen. Ted Cruz Rafael (Ted) Edward CruzThe Hill's Morning Report - Sponsored by Facebook - Washington on edge amid SCOTUS vacancy Murkowski: Supreme Court nominee should not be taken up before election Battle lines drawn on precedent in Supreme Court fight MORE (R-Texas) are rumored to be Trump's top choices to replace Sessions should he resign or be fired.