A strip club destroyed in an arson attack on Tuesday morning marks another flashpoint in an 18-month war waged by Comanchero bikie gang members on the security industry, police believe.

People were seen acting suspiciously around Kittens strip club on Glen Huntly Road in Caulfield South moments before the explosion about 3am.

It is the third time a Kittens strip club has been targeted since November, and the latest incident in a vicious campaign that has included seven non-fatal shootings.

While not naming the outlaw gang responsible for the violence, Detective Inspector Ian Campbell from the anti-bikie Echo task force said one particular club had been responsible for standing over security companies in a bid to claim lucrative contracts.