BROOKLINE — When it opens its doors for recreational marijuana sales on Saturday, NETA in Brookline will become the first adult-use marijuana store in Greater Boston and the first store accessible by public transportation.

Store officials are encouraging patrons to take advantage of that fact. “Parking is very, very limited in this area,” said Amanda Rositano, NETA’s director of compliance. “We are strongly encouraging people to take the T, to utilize public transportation.”

NETA is expecting massive crowds when it opens at 9 a.m. as the first legal recreational marijuana store within easy reach of Boston. NETA officials have experience handling hubbub — their Northampton dispensary was one of the first two stores in the state to open for recreational sales. The store opening attracted a few thousand people, according to company officials.

“This is an urban location, the first in Greater Boston, it is unique,” Rositano said. “I think our close coordination with the police department really prepares us for whatever might come.”

The store will be open from 9 a.m. to 10 p.m. Saturday and Sunday and from 10 a.m. to 10 p.m. Monday through Friday. The store will sell edibles, flower, pre-rolled joints, topical creams, vape pens, extracts and concentrates.

“We’ll have a robust menu,” Rositano said.

NETA is urging customers to place their orders ahead of time through its website. There will be separate lines for full-service and for customers who order online.

The company is also stressing the benefit of taking public transportation. NETA’s small parking lot will be closed to cars for the first few days after the store opens for recreational sales, and will be used to handle the long lines.

There is a parking lot across the street, on Route 9, solely for medical marijuana patients. NETA has reserved 25 spots at the Homewood Suites’ parking lot nearby, some of which will be reserved for patients. There are several nearby public parking garages, including a 377-car garage at One Brookline Place, and some metered spots. But Rositano warned that it will be difficult to find parking.

The store is located near the Brookline Village MBTA stop on the Green Line D branch and the Riverway station on the Green Line E branch. Due to construction this weekend on the D branch, shuttle buses will replace trains between Kenmore and Reservoir. The store is also near several bus lines — routes 39, 60, 65 and 66.

Some dispensaries have used far-away parking lots and shuttle buses to accommodate opening day crowds, but Rositano said NETA did not think that was necessary since the store is accessible via public transportation.

The store is capping sales of flower at one-eighth of an ounce for adult use sales. Patients will not be subject to that limit.

Rositano said NETA expects to have enough inventory to meet the demand.

Medical patients will have a separate line, and 35 percent of inventory each day will be reserved for medical patients. Staff will still offer in-depth consultations to patients.

“We’re trying to prioritize the patients,” said Andy Epstein, director of patient education for NETA.

NETA has doubled its staff in preparation for adult-use sales and now has more than 100 employees at the Brookline store.

The store has coordinated closely with Brookline officials. There will be at least 15 Brookline police officers on hand to direct traffic and control crowds, according to Brookline Police Lt. Philip Harrington. NETA will pay for the extra police detail.

Neil Wishinsky, chairman of the Brookline Board of Selectman, will be the first customer.

Wishinksy said if anyone asked him 10 years ago whether he would be an elected official welcoming the opening of a marijuana retailer, “I would have said you were crazy.”

“But here we are, and this is really a sign of how times have changed, and that elections really have consequences,” Wishinsky said. “And 60 percent of Brookline’s voters voted to legalize adult use cannabis.”

Wishinsky said the town’s focus will be on ensuring traffic moves smoothly, that parking works and that the disruption to neighbors is minimal. The store is located next to a day care center.

“There’s been very little controversy about this opening, but there’s been a lot of concern, and we’ll be working hard to make sure things go smoothly,” Wishinsky said.

Only adults over 21 with a valid ID will be allowed into the dispensary.

NETA will be the 13th legal marijuana store to open in Massachusetts. The next closest store to Boston, Alternative Therapies Group in Salem, has suspended recreational sales due to a problem uploading their inventory into the state tracking system.