That weekend jaunt up north to Dallas, or the Woodlands for that matter, might be one of the deadliest trips Houston drivers can take, according to a recent report.

The folks at finance and consumer research firm ValuePenguin, seen here, analyzed federal road safety data and found Interstate 45 is the second-most dangerous road in the U.S. Only California 99 that runs through the central part of the state had more fatal accidents, per-mile.

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Looking at fatal crashes from 2011 to 2015, the analysts found I-45 averaged 56.5 fatal accidents per 100 miles of roadway. Along I-45, the most dangerous city was Houston, with 51 fatal wrecks from 2011 to 2015.

According to the data, which looked at fatalities, the length of the road and other factors such as inclement weather and drunk driving wrecks, I-45 scored in the top five in both DUI-related crashes and fatal incidents at nighttime.

Other freeways around the state, or through the state, also made the list of top 20 most dangerous are: Interstate 10 which was fourth, Interstate 20 ranking eighth, Interstate 35 ranking No. 10 and Interstate 40 ranking No. 15.

In the Houston area, other freeways in the top 50 included U.S. 90 at No. 29 and U.S. 59 at No. 34.

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Keep in mind the analysis covers the entire freeway or highway, so for I-45 that is 285 miles, while for I-10 it is 2,460 miles. Running between Galveston and Dallas, I-45 also has a huge amount of traffic and it a major backbone of Houston area travel.

The same can be said for some of the major freeways. I-10 runs through Jacksonville, New Orleans, Houston, San Antonio, El Paso, Phoenix and Los Angeles. So it picks up a lot of urban crashes.

Still, on a day when Houston has already had three fatal crashes, including one on I-45, it’s hard to quibble with the conclusion we have some of the nation’s most dangerous streets.

Click through above to see the most dangerous highways in the U.S.