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A transgender high school wrestler has been accused of "cheating" - because his testosterone treatment allegedly gives him an unfair advantage over the girls he competes with.

Mack Beggs, 17, was booed by a handful of spectators following his victory in the quarter finals of the Texas state championships on Friday, which took his streak to 54 wins for zero losses.

Mack, of Trinity High School, was born female but is transitioning to a man, requiring hormone replacement therapy.

Although testosterone is a banned substance, Mack is allowed to take it because it is for "valid medical use".

(Image: Reuters) (Image: Facebook)

It is the state's athletic policy for students to compete against the gender assigned on their birth certificate.

Yesterday he defeated Taylor Latham and Mya Engert in the Class 6A girls 110-pound weight class by 18 points to 7 and 12-4 respectively.

He is now just two matches away from a state championsip.

One mother was reportedly heard calling Mack a 'big cheater' as he left the ring.

Taylor Latham's mother Lisa said she had wanted her daughter to forfeit the match "as a protective mom".

(Image: Facebook) (Image: Facebook)

"But she's a fighter. She's not a quitter," she said.

"Mack wants to wrestle boys and he'll never be recognized as a boy because of the birth certificate in the state of Texas."

The birth certificate policy was passed by the University Interscholastic League (UIL) last August, with 95 per cent of the vote.

Given the near unanimous support for the policy, UIL deputy director Jamey Harrison told reporters it was unlikley to change anytime soon.

(Image: Facebook) (Image: Facebook)

Mack himself has hit back at his critics, saying only parents and coaches have a problem with him wrestling girls.

Writing on Facebook, the teenager said he was "sick and disgusted by the discrimination of the adults.

"These kids don't care who you put in front of them to wrestle," he said. "We just want to WRESTLE.

"THEY are taking that away from me and from the people I'm competing with."