Mark Cuban is continuing his crusade against Republican presidential candidate Donald Trump.

In a tweet on Monday, the reality-TV star and investor said that Trump's comments about the Federal Reserve during his Monday interview with CNBC highlighted the candidate's risk to the global economy.

"Trump's comment on the Fed is exactly why the market will tank if he is elected," Cuban wrote in the tweet. "Ask him if he understands how the Fed works @cnbc."

Cuban has repeatedly said that he believes there would be serious market turmoil if Trump were elected, predicting a stock market drop of 20% if he defeated his Democratic rival, Hillary Clinton.

Cuban also took exception with Trump's suggestion that the Fed is not politically independent, as it is designed to be.

"Dear Donald, if the @federalreserve is truly political they will announce that if you are elected there will be a HUGE rate increase," Cuban wrote in a tweet.

Trump suggested in his CNBC interview that the Fed and Board Chair Janet Yellen are keeping interest rates low in order to sustain the economy until President Barack Obama is out of office. He said Yellen should be "ashamed" of her actions.

"So I used to think they were independent, and the Fed is obviously not independent," Trump said in the interview. "It's obviously not even close to being independent."

Cuban also tweeted that Trump's suggestion that the Fed is "corrupt" shows "how uninformed he is."

Here are Cuban's tweets: