This is the bi-weekly visible open thread (there are also hidden open threads twice a week you can reach through the Open Thread tab on the top of the page). Post about anything you want, but please try to avoid hot-button political and social topics. You can also talk at the SSC subreddit or the SSC Discord server – and also check out the SSC Podcast. Also:

1. Comments of the week: scchm presents an apparently original theory that buspirone works on D4 receptors (but see the whole thread, including my comments). And Murphy gives some pointers for determining when to believe claims of large effects from single genes.