Rep. Ron DeSantis Wednesday called on the Department of Justice to investigate several key Obama-era officials, as well as Democratic nominee Hillary Clinton and former FBI Director James Comey, for crimes, pointing out Comey's recommendations on Clinton.

"Remember, he testified to Congress that he did not make any decision regarding Secretary Clinton until after she was interviewed," the Florida Republican, a member of the House Judiciary Committee, told Fox News' "Fox & Friends."

"He was asked that specifically by one of my colleagues and, yet, the evidence has he come out since then demonstrates that actually they made this determination months before, not only interviewing Secretary Clinton, but also interviewing a number of key witnesses."

DeSantis is one of 11 conservative Republicans who sent a letter Wednesday to Attorney General Jeff Sessions, FBI Director Christopher Wray and U.S. Attorney John Huber, according to The Hill.

Other signing the letters included Reps. Andy Biggs, Arizona; Dave Brat, Virginia; Jeff Duncan, South Carolina; Matt Gaetz, Florida; Paul Gosar, Arizona; Andy Harris, Maryland; Jody Hice, Georgia; Todd Rokita, Indiana; Claudia Tenney, New York; and Ted Yoho, Florida.

Show co-host Brian Kilmeade pointed out that Comey and former Deputy Attorney General Sally Yates began to draft a letter in May 2016 about Clinton.

Comey didn't sit down with her, but Peter Strzok, one of the two FBI agents who ended up removed from the Russian investigation over his anti-Trump texts with fellow FBI agent Lisa Page, did, said Kilmeade.

"You notice they are supposedly going after Michael Cohen for FEC (Federal Elections Commission) violations because of this non-disclosure payment," said DeSantis, referring to a $130,000 fee Cohen paid to adult film star Stormy Daniels before the 2016 election.

"That's not really a theory that's been tried before," he said. "It seems a little odd to me. If that is potentially an offense, well, is it camouflaging these payments?"

The Clinton campaign, meanwhile, "disguised the fact" that it paid for opposition research that eventually lead to a salacious dossier about Trump.

"That's not the way the federal election laws are supposed to work," said DeSantis. "You are supposed to expose your expenditures. If you are going after Cohen why isn't anybody going after how the Clintons handled this?"

A former FBI informant also testified to Congress that he was threatened by Lynch's Justice Department over coming forward on the Uranium One matter involving Clinton, and that's another serious issue that needs examining, said DeSantis.