Tottenham may have to face Manchester United without No. 1 goalkeeper Hugo Lloris. Paul Gilham/Getty Images

Hugo Lloris is likely to miss Tottenham's trip to Manchester United on Saturday, Mauricio Pochettino has confirmed.

Lloris, 28, came off the bench to play the last 30 minutes of Spurs' 2-0 victory over AC Milan in the Audi Cup on Wednesday -- his first appearance since breaking his wrist last month.