Gareth Southgate has had his England plans thrown into chaos with Harry Kane and Harry Winks pulling out of the squad.

Kane took a kick on his leg on Sunday and underwent a scan on Monday with Tottenham anxious that no risks are taken as he also had a hamstring problem last week.

Tottenham midfielder Winks has also undergone a scan on an ankle injury and will miss the friendlies with Germany and Brazil.

Both have pulled out without reporting up.

(Image: Tottenham Hotspur FC)

(Image: Getty)

But it's a massive blow for Southgate, particularly to lose Kane for prestigious friendlies which were seen as vital in terms of World Cup preparation.

Kane, 24, has scored 12 goals in 23 games but Spurs are anxious to have him fit for their domestic campaign.

Gary Cahill and Jordan Henderson have also remained at their clubs with Chelsea and Liverpool respectively but both could miss out. Everton’s Michael Keane and West Brom's Jake Livermore have been drafted in.

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Tottenham’s Dele Alli has already withdrawn because of a hamstring injury.

It is a blow for Southgate to lose big players for two major tests at Wembley and will be a major frustration.