Ryan Reynold’s “ Deadpool 2 ” is set to take the No. 1 box office crown from “ Avengers: Infinity War ” this weekend, with $133.5 million from 4,349 North American locations.The third R-rated superhero film from Fox took in $53.3 million Friday, including a record-setting $18.6 million from Thursday previews, the highest Thursday tally for an R-rated film (“It” had previously held the title with $13.5 million). “ Deadpool 2 ’s” 4,349 theaters also mark Fox’s widest launch ever.The “ Deadpool ” sequel will break its own predecessor’s record as the highest opening weekend for an R-rated film — “ Deadpool ” stunned the industry two years ago with $132.4 million. The original’s unique take on the superhero genre, with Reynolds breaking the fourth wall to address the audience directly, made the film a must-see, and it went on to earn $363 million in North America and $783 worldwide, making it the highest-grossing R-rated movie of all time.Reynolds returns as the wisecracking