FB3® Technical Brochure INQUIRE

WHAT’S IN FB3?

FB3 is a proprietary blend of three well-known natural ingredients: Coleus forskohlii, Salacia reticulata, and Sesamum indicum – standardized for diterpene forskolin, kotanol and salacinol, and sesamin, respectively. Individually, each of these components has been shown to inhibit fat absorption with differing degrees and dynamics.

salacia reticulata root extract comes from a climbing woody plant native to India, which has played a role in traditional Ayurvedic medicine as an anti-diabetic herb with established inhibitory action on alpha glucosidase, an enzyme that prevents absorption of excess dietary sugar. Salacia reticulate appears to have the ability to block fat and may reduce the rate of lipid (fat) absorption after a meal.

Sesamum indicum seed extract, which comes from sesame seeds, also exerts this activity.This superfood is also a rich source of protein and many essential minerals that is believed to support healthy cardiovascular and circulatory functions.

Coleus forskohlii is best known for supporting weight management. This plant, which comes from the mountains of Asia, has been used for centuries in traditional Indian food, pickles as well as in Ayurvedic medicines. Coleus forskohlii supports fat loss through a cascade of chemical reactions – especially its ability to facilitate the action of hormones within the body. Balanced hormonal activity corresponds well with a healthy metabolism and helps the body prevent storage of excess fat. In addition, studies have shown that Coleus forskohlii reduces the percentage of body fat and decreases waist circumference, visceral fat, cholesterol, blood triglycerides, and caloric intake. However, when used alone, Coleus forskohlii may not work equally effectively in men and women, and its effectiveness may decrease with continued use and as people age.

FB3 is a safe and effective nutraceutical fat-absorption inhibitor, an innovative fusion of three well-established natural ingredients: Coleus forskohli, Salacia reticulata and Sesamum indicum.

PROPOSED FB3 STRUCTURE /FUNCTION APPLICATION

Weight management: A proprietary blend of Coleus forskohlii, Salacia reticulata, and Sesamum indicum, FB3 inhibits fat absorption without negative side effects. The synergistic action of FB3 provides twice the fat-absorption inhibition activity as each of its individual components. It also helps prevent negative gastrointestinal and metabolic side effects often associated with fat blockers.

FB3 DISTINCTION

When provided as FB3, Coleus forskohli, Salacia reticulata, and Sesamum indicum supply a safe and effective method of blocking fat. A clinical study showed that FB3 led to diminished visceral fat, liver fat, body triglycerides, food cravings and caloric intake. And, an in vitro study found that the synergistic action of the Coleus forskohlii and Salacia reticulata in FB3 inhibited fat absorption by 20.7% – almost double the sum of the fat-blocking activity generated by each component alone.

But perhaps the most exciting result of this FB3 study is identification of the ingredient’s inherent “safety mechanism,” which occurs with the interaction of Coleus forskohlii and Sesamum indicum. This safety mechanism is intended to moderate FB3’s fat-absorption inhibition abilities, helping prevent the negative gastrointestinal and metabolic side effects that frequently occur with other fat blockers.

The study also showed that Coleus forskohli and Salacia reticulata work synergistically to prevent tachyphylaxis, the phenomenon of diminished response to regularly consumed ingredients for targeted action over time. This means that FB3 won’t become less effective over time or as people age – which is a problem with many fat blockers.

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