A man wanted for allegedly threatening to kill his wife is being sought in connection with a Southwest Side shooting Thursday that left her injured.

According to police, Javier De Hoyos, 52, pulled up alongside his estranged wife’s vehicle as she drove to work near the 3500 block of South Gen. McMullen. He is accused of firing several shots into her car, striking her three times, police said.

The 41-year-old woman fled and sought refuge inside the gates of the former Kelly AFB.

“She was fortunate enough to be able to drive onto the base here, and when she did that, he turned around and went the other way,” Police Chief William McManus said.

The woman was transported to a hospital in stable condition.

A bullet also struck a side window near the rear of a No. 62 VIA Metropolitan Transit bus during the incident, officials said. No one on the bus was injured.

After De Hoyos fled the scene, police said, he eventually crashed his truck near St. Ann and West Ashby Place on the North Side and then fired several rounds into the air.

Police said De Hoyos then attempted to set a nearby house on fire and fired more rounds into the air. Witnesses last saw him on St. Ann.

A search for De Hoyos in the area was conducted by police, including SWAT team. At one point, police believed that he may have been barricaded inside a home he had ties to on Cincinnati, and they secured the area, ordering neighbors to evacuate or shelter in place.

Around noon, police learned that De Hoyos was not in the house and continued their search. They released his photo, noting that he was last seen driving a black 2000 Ford F-150 Harley Davidson truck with a Texas license plate: GMC0010.

On March 5, De Hoyos was served with a protective order for his wife. He is accused of waiting for her to leave work the next day and threatening her with a gun. She screamed and was able to escape. A felony warrant for aggravated assault with a deadly weapon was issued for his arrest.

On Thursday afternoon, as police pulled down yellow tape on St. Ann, Oscar Vasquez recalled the chaos that had erupted in his neighborhood.

Vasquez, who said the suspect’s daughter lives in the neighborhood, reported hearing two bursts of three gunshots fired into the air.

A gang used to operate in the area, Vasquez said, noting that residents “have to know how to dodge bullets.”

Vasquez pointed out the proximity of St. Ann’s Catholic Church and Beacon Hill Academy, both steps away from where the police set up their cordon.

He said he was glad the students at the school were on Spring Break. Although he heard the shots, Vasquez did not see De Hoyos allegedly fire into the air or attempt to set a house on fire.

“I was too far,” he said. “I’m glad I was too far.”

If you see De Hoyos or know his whereabouts, police ask that you do not make contact with him and call 911.

mark.dunphy@express-news.net | @m_b_dunphy