Person of Interest has tapped Emmy winner Camryn Manheim (The Practice, Ghost Whisperer) and Saul Rubinek (Warehouse 13) to anchor an emotional plot that will play out over multiple Season 3 episodes, TVLine has learned exclusively.

Manheim will play Diane, a devoted wife whose husband, the brilliant Arthur (Rubinek), is slowly losing his mind. While the POI team risks putting her in danger, they must rely on Diane to break through to her husband in order to save both their lives.

Their arc on the CBS procedural is slated to kick off in early 2014.