The first spark of anger activities the amygdala before you are even aware of it. The amygdala activates the hypothalamus. The hypothalamus signals the pituitary gland by discharging corticotropin releasing hormone. The Pituitary activates the adrenal glands by releasing adrenocorticotropic hormone The adrenal glands secrete stress hormones like cortisol, adrenaline and nor-adrenaline.

How anger changes your brain

Elevated cortisol causes neurons to accept too much calcium through their membrane. A calcium overload can make cells fire too frequently and die. The hippocampus and prefrontal cortex are particularly vulnerable to cortisol and these negative effects.

Too much cortisol will decrease serotonin: that is the hormone that makes you happy. A decrease in serotonin can make you feel anger and pain more easily as well as increase aggressive behavior and lead to depression.

How Stress Hormones Affect Your Body

Neurologist said due to anger when heart rate, blood pressure, arterial tension, blood glucose level and blood fatty acid level increases it can lead to damage and clot of blood vessels. Therefore, this can lead to stroke and heart attack.

Neurologist added Anger can cause decrease of thyroid function, the number of natural killer cells, the number of virus infected cells and increases incidence of cancer.

Anger can cause decrease in blood flow, metabolism and eventually increases the dry mouth.

Other causes includes Spine problem, pain management, Eye sight, migraines, headaches and decrease in bone density.

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