1. Buy Erlocip 100mg Online

Erlocip-100 containing the active ingredient erlotinib is considered a tyrosine kinase inhibitor type of medication. The medication works by interfering with the protein epidermal growth factor to prevent it from activating enzymes certain cancer cells require to grow and multiply. The tablets can be used along with other medications or other types of cancer treatment to treat non small cell lung cancer and pancreatic cancer that has spread to nearby tissues or to other parts of the body.

2. How To Erlocip 100mg Work?

Erlocip tablets 100mg contain erlotinib, a potent inhibitor of tyrosine kinase, an enzyme that phosphorylates a protein inside a cell, which is the way many cell processes are regulated. Tyrosine kinases (TK) are cell surface receptors for many cellular messengers including growth factors and erlotinib in Erlocip tablets 100mg acts as a potent inhibitor of the Epidermal Growth Factor receptor (EGFR). EGF stimulates cell growth, proliferation and differentiation in normal cells. It acts by binding with high affinity to its cell surface receptor EGFR, which belongs to the TK family of receptors. When EGF binds to EGFR, the receptor undergoes a shape change, which activates TK activity by phosphorylation of its substrates within the cell and this is the first step in a complex cell signalling pathway involved in cell proliferation and survival. Normally EGFR activation is regulated and therefore, cell proliferation is controlled and programmed cell death (apoptosis) takes place. However, the mutation associated with NSCLC leaves the receptor in a state that is constantly activated or turned on (constitutively activated) even when EGF is not bound to the receptor. This results in cells that are stimulated to constantly proliferate and survive leading to NSCLC. Over-expression of the EGFR is thought to be associated with malignant transformation and metastasis of pancreatic cancer, due to the pancreatic cells being over stimulated to proliferate and grow. Erlotinib in Erlocip tablets 100mg works by blocking the intracellular phosphorylation of EGFR, which blocks the signalling pathway for cell proliferation and survival in NSCLC cells and pancreatic cancer cells. This action of Erlotinib in Erlocip tablets 100mg blocks the proliferation of the tumour cells and induces cell death, which results in tumour regression.

3. What is Erlocip 100mg Tablet?

Erlocip tablets contains the active ingredient erlotinib hydrochloride 100mg, a potent inhibitor of tyrosine kinase cell surface receptor for Epidermal Growth Factor receptor (EGFR), used to treat NSCLC and advanced pancreatic cancer.

4. How To Take Erlocip 100mg Tablet?

You should take your Erlocip tablets 100mg swallowed whole with a glass of water at least one hour before or two hours after the ingestion of food. The dose you take and for how long depends on what you are being treated for and your doctor’s recommendation. For pancreatic cancer you should take your Erlocip tablets 100mg in combination with gemcitabine. You should continue to take your Erlocip tablets 100mg until your disease becomes worse or you show signs of toxicity from the medication, dependent on your doctor’s recommendation.

5. Drug interaction of Erlocip 100mg

Several medications interact with Erlocip tablets 100mg and should either not be taken while you are taking Erlocip or only after discussion and instruction from your doctor:

Drugs that cause a serious reaction with Erlocip: corticosteroids and NSAIDs can increase risk of gastrointestinal perforation; statins for high cholesterol can increase risk of myopathy (muscular weakness), anticoagulants like warfarin cause increased bleeding

Drugs that affect Erlocip: the immunosuppressant cyclosporine, verapamil for hypertension, proton pump inhibitors like omeprazole, antifungals like ketoconazole, antibiotics like ciprofloxacin, erythromycin, clarithromycin, rifampicin, anticonvulsants like phenytoin, carbamazepine, ranitidine for reflux, St. John’s Wort

Drugs that are affected by Erlocip: anticoagulants like warfarin,

6. Side Effects of Erlocip 100mg

Nausea

Vomiting

Loss of appetite

Dry skin

Weight loss

Fatigue

Mouth sores

Vision problems

Signs of infection

Abdominal pain

Breathing problems

Mental or mood changes

Persistent cough

Unusual bruising or bleeding

7. Warning of Erlocip 100mg tablet

Do not use the medication within 2 hours of taking an antacid as it may prevent the absorption of the drug.

Immediately proceed to your nearest emergency department if you suffer an allergic reaction. Symptoms usually associated with such a reaction include difficulty breathing or swallowing, chest tightness, swelling, skin rashes, and hives.

Erlocip-100 is not always suitable for all patients. Always consult your health care provider prior to using this medication if you are pregnant, breastfeeding, trying to conceive, using any other medication (prescription or non-prescription), using any herbal products or supplements, or if you have any allergies or other health problems.

The correct dosage and prescription commonly depend on the patient and the condition being treated. Do not adjust your dosage without the approval of your health care provider. This product is only for use as prescribed and instructed.

8. Precaution of Erlocip 100mg tablet

You should not use Erlocip tablets 100mg if you:

are allergic to erlotinib or any ingredients in Erlocip

are pregnant or are breastfeeding

have kidney or liver disease

are having immunisation with live vaccine

use contact lenses and/or have a history of eye problems

have gastrointestinal problems particularly diarrhoea as this can worsen with Erlocip

have prior history of peptic ulceration or diverticular disease as this can increase risk of gastrointestinal perforation

are a smoker

have interstitial lung disease

are taking medicines that interact with Erlocip, including corticosteroids and NSAIDs for pain and inflammation, statins for high cholesterol, anticoagulants like warfarin, the immunosuppressant cyclosporine, verapamil for hypertension, proton pump inhibitors like omeprazole, antifungals like ketoconazole, antibiotics like ciprofloxacin, erythromycin, clarithromycin, rifampicin, anticonvulsants like phenytoin, carbamazepine, ranitidine for reflux

9. Erlocip 100mg Dosage

If you miss a dose of Erlocip tablets 100mg take it as soon as you remember, unless it is time to take the next dose, then skip the missed dose. Do not take a double dose.

10. Uses of Erlocip 100mg

Erlocip tablets 100mg are used to treat non-small cell lung cancer (NSCLC), which is the most common form of lung cancer and grows more slowly than small cell lung cancer (SCLC). NSCLC is associated with a mutation in the gene for Epidermal Growth Factor receptor (EGFR)1 and treatment of NSCLC with Erlocip tablets 100mg is only effective where an EGFR mutation is present in the tumour cells2. Erlocip tablets 100mg are used for treatment of locally advanced (stage III) or metastatic (stage IV) NSCLC either as first-line treatment, as monotherapy maintenance treatment for stable disease after 4 cycles of standard platinum-based first-line chemotherapy or after failure of at least one prior chemotherapy regimen. Erlocip tablets 100mg are also used to treat locally advanced, unresectable (inoperable) or metastatic pancreatic cancer in combination with gemcitabine, an anti-cancer drug used for chemotherapy. Advanced pancreatic cancer has a very poor survival rate and Erlocip tablets 100mg in combination with gemcitabine can improve the survival rate.

11. Storage of Erlocip 100mg