Wayne Rooney is the most high-profile member of the Manchester United squad to be left out of Jose Mourinho's first Europa League selection.

Rooney has not been named in the 20-man squad to travel to Holland, as Mourinho takes his side to face Feyenoord.

Henrikh Mkhitaryan and Jesse Lingard - both of whom were taken off at half time during the Manchester derby defeat last weekend - are also both out of the squad, as are England full-back Luke Shaw and wing-back Antonio Valencia.

Wayne Rooney (right) have been left out of Jose Moruinho's first Europa League squad

Anthony Martial (left) and Marcus Rashford sign autographs as they fly to Holland

Juan Mata prepares to jet off to take on Feyenoord with his United team-mates

Mourinho left several of his first-team stars at home, but wants to get off to a winning start

Zlatan Ibrahimovic walks through as United head off to begin their European campaign

MANCHESTER UNITED SQUAD TO FACE FEYENOORD De Gea, Romero, Johnstone; Darmian, Bailly, Blind, Fosu-Mensah, Rojo, Smalling; Carrick, Fellaini, Herrera, Mata, Memphis, Pogba, Schneiderlin, Young; Ibrahimovic, Martial, Rashford Advertisement

Rooney was pictured in training on Wednesday morning, as was Lingard, although Mkhitaryan was among those who missed out through injury.

The squad does include the likes of Paul Pogba and Zlatan Ibrahimovic however, and Mourinho seems determined to return to winning ways after losing the derby 2-1 at Old Trafford on Saturday.

Morgan Schneiderlin (left) and Ashley Young were both included in the 20-man squad

Sir Bobby Charlton travelled with the team as they prepare for their Europa League clash

Young defender Timothy Fosu-Mensah looked in good spirits ahead of the flight

Rooney seemed in good spirits during training on Wednesday, but will not travel to Holland

The United and England captain was put through his paces by Mourinho and his coaches

Jesse Lingard (centre) and Luke Shaw (right) were also left out of the 20-man squad

Rooney stretches ahead of the Feyenoord trip, but he will not be one of those involved

The United forward, who played behind Zlatan Ibrahimovic on Saturday, adjusts his clothing

The United boss said after that difficult defeat that he wanted to move on as quick as possible and the match in Rotterdam gives him the perfect opportunity.

United are favourites to progress to the Europa League knockout stages from Group A, which also includes Fenerbahce and Zorya Luhansk.

Mourinho will, however, fly with his players to Holland knowing that Feyenoord are top of Eredivisie after winning all five of their games.

10m-high nets around the pitch at the De Kuip for Utd's game here to stop fans throwing missiles pic.twitter.com/2GZlKt88on — Chris Wheeler (@ChrisWheelerDM) September 14, 2016

Lingard was taken off at half time in the derby defeat, and is not part of the squad to travel