The regional semifinals are set. What can we expect when the games resume in the women's NCAA tournament?

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Will the chalk hold?

Will Cinderella runs continue?

Will any of the No. 1 or No. 2 seeds fall?

What are the biggest X factors in each Sweet 16 game?

ESPN's Charlie Creme, Elizabeth Merrill, LaChina Robinson and Mechelle Voepel make their game-by-game picks and predictions:

AP Photo/Gerry Broome

No. 3 NC State vs. No. 2 Iowa

ESPN/ESPN App: 11:30 a.m. ET Saturday (Greensboro Regional)

X factor: Megan Gustafson is going to do her thing for Iowa. But guards Makenzie Meyer and Kathleen Doyle combined for 33 points in the second round, which was a big part in beating Missouri. NC State will need to guard the 3-point arc well while still trying to limit Gustafson. -- Mechelle Voepel

Picks:

Creme: NC State

Merrill: NC State

Robinson: Iowa

Voepel: NC State

AP Photo/Jason E. Miczek

No. 4 South Carolina vs. No. 1 Baylor

ESPN/ESPN App: 1:30 p.m. ET Saturday (Greensboro Regional)

X factor: It's hard enough to have to face standout Baylor post players Kalani Brown and Lauren Cox. But Baylor's guard play was as big a problem for Cal in the second round. In South Carolina, Baylor will be facing a team with the guard depth to challenge the Lady Bears. -- Mechelle Voepel

Picks:

Creme: Baylor

Merrill: Baylor

Robinson: Baylor

Voepel: Baylor

AP Photo/David J. Phillip

No. 4 Texas A&M vs. No. 1 Notre Dame

ESPN2/ESPN App: 4 p.m. ET Saturday (Chicago Regional)

X factor: The Aggies got double-digit scoring from all five starters just twice all season, but it happened in their second-round win over Marquette. Chennedy Carter still led the way with 30 points, but getting contributions from everyone might be the only way Texas A&M can stay competitive with the most balanced offense in the country. -- Charlie Creme

Picks:

Creme: Notre Dame

Merrill: Notre Dame

Robinson: Notre Dame

Voepel: Notre Dame

AP Photo/Ben Margot

No. 11 Missouri State vs. No. 2 Stanford

ESPN2/ESPN App: 6 p.m. ET Saturday (Chicago Regional)

X factor: The Lady Bears have had the luxury of playing two teams (DePaul and Iowa State) with a similar style in the opening two rounds. Stanford will play inside-out. How Missouri State handles the Cardinal's size and length will determine how competitive the game is. -- Charlie Creme

Picks:

Creme: Stanford

Merrill: Stanford

Robinson: Stanford

Voepel: Stanford