Patients are being diverted from Perth's troubled Fiona Stanley Hospital due to a large water leak flooding parts of the new hospital.

The hospital confirmed a main water pipe that supplies the ward towers burst causing major flooding earlier on Sunday.

As a result, eight operating theatres have been closed and some elective surgery scheduled for Monday has been cancelled.

It has also affected hot water and air conditioning systems in the hospital.

A hospital spokeswoman said all ambulance and chopper patients were being diverted to other hospitals.

It is understood the hospital is on a code yellow, signifying an emergency situation.

Inquiry into hospital likely

Ambulances queuing at Sir Charles Gairdner Hospital in Perth after Fiona Stanley Hospital diverts all patients. ( ABC News: Layla Tucak )

Fiona Stanley Hospital has been fraught with problems since its opening and the State Opposition has called for a parliamentary inquiry.

In recent weeks there have been numerous other issues raised, including surgical equipment not being properly sterilised, medical consultants quitting because of excessive workloads, and concerns about the delivery of intravenous drips and other medical supplies to wards.

An inquiry seems likely, after a Liberal committee member indicated he would support it.

The Education and Health Standing Committee is set to discuss on Monday whether to hold an inquiry.

The committee, which already conducted an inquiry into the commissioning of the new $2 billion hospital before it opened, has three Liberal MPs and two Labor MPs.

The ABC understands the two Labor MPs, Rita Saffioti and Janine Freeman, are likely to support an inquiry, which means with Liberal MP Rob Johnson also in favour of a new probe, it appears likely to happen.

Health Minister Kim Hames hit out at the Opposition, accusing them of denigrating the hospital and undermining public confidence in it.