(CNN) When Sen. John McCain's family announced Friday that he was ending medical treatment for aggressive brain cancer, the news shook Capitol Hill and prompted support from his Republican and Democratic colleagues alike. But one prominent voice was missing: President Donald Trump's.

The White House press office did not react to the news, and when Trump traveled to Ohio in the evening he did not mention the ailing senator in a nearly hour-long speech to Ohio Republicans, which ran a gamut of topics from the death of Mollie Tibbetts to NFL protests to Kanye West.

In past months, Trump has frequently referenced McCain's 2017 health care vote on the campaign trail without naming him, drawing the ire of the Arizona Republican's family.

"One of our wonderful senators said 'thumbs down' at 2 o'clock in the morning," the President said at a campaign event for New York's Rep. Claudia Tenney earlier this month.

The senator's daughter, conservative commentator Meghan McCain, called Trump's comments "gross and pathetic" at the time.

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