CINCINNATI -- Derek Dietrich was describing his three-homer game for the media when Scooter Gennett walked past and put it in a slightly different perspective.

"Anybody can hit three, Derek,'' said Gennett, who did him one better in 2017.

No, Dietrich's latest big game didn't set any records. But it extended one of the most unexpected home run tears by a Cincinnati Reds player in recent years. Dietrich hit three homers -- all two-run shots -- and the Pittsburgh Pirates suffered yet another injury to their rotation Tuesday night as Cincinnati pulled away to an 11-6 victory.

"This is more than just a hot streak,'' Reds manager David Bell said.

Dietrich grounded out in his first at-bat and connected in the fourth off Jordan Lyles (5-2), who left after the inning with discomfort in his left hamstring. Dietrich then connected off Geoff Hartlieb in the fifth and again in the seventh for his first three-homer game.

After the third homer, the 13,824 fans at Great American Ball Park demanded a curtain call. Still holding his batting helmet, Dietrich emerged from the dugout and raised both arms.

He didn't get another at-bat to try to match Gennett, who tied the major league record with four homers at Great American Ball Park on June 6, 2017.

Signed to a minor league deal in February with a chance to compete for a spot off the bench, Dietrich has received playing time with Gennett sidelined since spring training due to a groin injury. Dietrich's 17 homers already has set a career high, and 12 of his past 17 hits have been home runs.

It only took Dietrich 118 at-bats to get to 17 homers, the seventh fewest at-bats by a player with 17 homers since 1961, behind luminaries such as Barry Bonds (116), Albert Pujols (112) and Mark McGwire (93).

"They let me be myself,'' Dietrich said. "They believe in me. They gave me an opportunity. That's all I've ever needed along the way.''

Most of the damage has been against the Pirates, who have allowed eight of his homers.

"He's hitting our mistakes extremely well,'' Pirates manager Clint Hurdle said. "The balls are not where we wanted them, and he's clobbered them.''

Lyles had an awkward follow-through on a pitch in the fourth but completed the inning. The Pirates already are missing starters Jameson Taillon and Trevor Williams. They've had 22 players on the injured list this season, with starter Chris Archer also missing time because of a sore thumb.

Now, there's a chance Lyles will have to miss time, as well.

"We've got the injury bug so far this year,'' Lyles said. "Everybody knows it.''

With its seventh loss in nine games, Pittsburgh fell to 26-27, the first time the Pirates have been below .500 since May 3.

Lucas Sims (1-0) was called up pregame and struck out a career-high nine in 7⅓ innings, the longest outing of his career. He gave up Kevin Newman's grand slam in the eighth, the rookie's first major league homer.

The Associated Press contributed to this report.