Augmentin Tablets, Suspension And Injections

Augmentin Tablets, Suspension And Injection includes Amoxicillin and Calvulanic Acid. Which is used for the treatment of acute bacterial sinusitis, acute otitis. And it also use in acute exacerbations of chronic bronchitis.

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Augmentin Tablets Injections And Suspension Indications

(Co-Amoxiclav) Augmentin Tablets is an antibiotic agent with a notably broad spectrum of activity against the commonly occurring bacterial pathogens in general practice and hospital. On the other hand The B-lactamasa inhibitory action of clavulanate extends the spectrum of amoxycillin to embrace a wider range of organisms. However Including many resistant to other B-lactam antibodies. On the other hand Augmentin Uses in accordance with local official antibiotic prescribing guidelines.

Augmentin Uses:

In Augmentin Oral Use for three times daily dosing indicated for short term treatment of bacterial infections at the following sites:

Augmentin Use in Upper respiratory tract infections Like. tonsillitis, sinusitis, otitis media

in Upper respiratory tract infections Like. tonsillitis, sinusitis, otitis media Co Amoxiclav Uses (Augmentin) Lower respiratory tract infections Like. acute exacerbation of chronic bronchitis, lobar and bronchopneumonia.

Genito urinary tract infections like. cystitis, urethritis, pyelonephritis.

Skin and soft tissue infections like boils, abscesses, celluitis, wound infections.

Bone And joint infections Like osteomyelitis.

Dental infections Similarly. dentoalveolar abscess

Other infections Likewise. intra abdominal sepsis

Infections caused by amoxycillin susceptible organisms amenable to Augmentin treatment due to its amoxycillin content.

Mixed infections caused by amoxycillin susceptible organisms in conjunction with Augmentin susceptible B-lactamase producing organisms may therefore be treated with Augmentin.

Augmentin Tablets Dosage And Administration

Usual Augmentin Dosage For The Treatment Of Infection:

Augmentin Dose For Adults & Children Over 12 Years

Mild Moderate Infections :

One Augmentin Tablets 375 mg tablet 3 times a day.

Severe Infections:

One Augmentin 1 g tablet twice daily

One Augmentin Tablets 625 mg 3 times a day. Where the 625 mg tablet not available, a dose of two Augmentin 375 mg tablets 3 times a day may taken. On the other hand the therapy can started parenterally and continued with an oral preparation.

Augmentin Dose For Children:

The usual recommended daily Augmentin Tablets Dosage is 25/mg/kg/day in divided doses every eight hours.

Under One Year :

25/mg/kg, for example a 7.5 kg child would require 2ml Augmentin 156 mg suspension 3 times a day.

1 to 6 Years (10-18) Kg:

5 ml Augmentin 156 mg suspension 3 times a day.

Over 6 Years (18-40 kg):

5 ml Augmentin 312 mg suspension 3 times a day.

However, In more serious infections the dosage may increased up to 50 mg/kg/day in divided doses every eight hours.

Augmentin Dosage In Dental Infections

Adults And Children Over 12 Years: One Augmentin 375 mg tablets 3 times a day for five days.

Augmentin Dosage in Hepatic Impairment:

Augmentin Tablets Dose with caution: monitor hepatic function at regular intervals. Each Augmentin 375mg, 625 mg, and 1 g tablet contains 0.63 mmol (25 mg) of potassium.

Augmentin Administration

The minimize potential gastrointestinal intolerance, administer at the start of a meal. The absorption of Augmentin optimized when taken at the start of a meal. Most Importantly the Treatment should not extended beyond 14 days without review.

Augmentin Drug Interactions

Augmentin Interaction Cocomitant use of probenecid not recommended. On the other hand Probenecid decreases the renal tubular secretion of amoxycillin. However, Concomitant use with Augmentin Dose may result in increased and prolonged blood levels of amoxycillin but not of clavulanate. On the other hand Concomitant use of allopurinol during treatment with amoxycillin can increase the likelihood of allergic skin reactions. In addition There are no data on the concomitant use of Augmentin and allopurinol.

In common with other antibiotics, Augmentin Use may affect the gut flora, leading to lower oestrogen reabsorption. And reduce efficacy of combined oral contraceptives. In the literature there are rare cases of increased international normalised ration in patients maintained on acenocoumarol or warfarin and prescribed a course of amoxycillin. If co-administration necessary the prothrombin time or international normalised ratio should carefully monitored with the addition or withdrawal of Augmentin. In patients receiving mycophenolate mofetil, reduction in pre-dose concentration of the active metabolite mycophenolic acid of approximately 50 % has reported following commencement of oral amoxycillin plus clavulanic acid. The change in Augmentin Pre-Dose level may not accurately represent changed in overall MPA exposure.

Augmentin In Pregnancy And Lactation

Reproduction studies in animals (mice and rats) with orally and parenterally administered Augmentin In Pregnancy shown no teratogenic effects. In a single study in women with pre-term, premature rupture of the foetal membrance(pPROM). However It was reported that prophylactic treatment with Augmentin Dose may associated with an increased risk of necrotising enterocolitis in neonates. As with all medicines, Augmentin use should avoided in pregnancy. Especially during the first trimester unless considered essential by the physician. However, Augmentin Use may administered during the period of lactation. So, With the exception of the risk of sensitisation, associated with the excertion of trace quantities in breast milk. However, there are no detrimental effects for the infant.

Augmentin Tablets, Injections Suspensions Side Effects

Date from large clinical trials used to determine the frequency of very common to rare undesirable Augmentin 875, Augmentin 1g, Augmentin 625mg, Augmentin 125mg Side effects. However, The frequencies assigned to all other undesirable effects where mainly determined using post-marketing data and refer to a reporting rate rather than a true frequency.

Augmentin Side Effects Infections And Infestations:

Common Mucocutaneous Candidasis

Blood And Lymphatic System Disorders:

Rare Reversible leucopenia and thrombocytopenia

Very Rare Reversible agranulocytosis and haemolytic anaemia. Prolongation of bleeding, Prothrombin Time.

Immune System Disorders:

Very Rare > Angioneurotic oedema, anaphylaxis, serum sickness like syndrome, hypersensitivity vasculitis.

Nervous System Disorders:

Uncommon > Dizziness, headache

Very Rare > Reversible hyperactivity and convulsions, convulsions may occur in patients with impaired renal function or in those receiving high dose.

Gastrointestinal Disorders:

Very Common > Diarrhoea

Common > Nausea, Vomiting

Hepatobiliary Disorders:

Uncommon > A moderate rise in AST or ALT has noted in patients treated with beta lactam class antibiotics. But the significance of these findings is known.

Very Rare > Hepatitis and cholestatic jaundice. These events noted with other pencillins and cephalosporins. On the other hand Hepatic events reported predominantly in males and elderly patients and may associated with prolonged treatment. So These events have very rarely reported in children.

Skin And Subcutaneous Tissue Disorders:

Uncommon > Skin Rash, Pruritus, Urticaria

Rare > Erythema Multiforme

Very Rare > In addition it shows Stevens Johnson syndrome, toxic epidermal necrolysis, bullous exfolitative dermatitis. Similarly acute generalised exanthemous pustulosis and drug reaction with eosinophilia and systemic symptoms.

Augmentin Tablets Syrup Injections Contraindications

This medicine is contraindicated in patients with a history of hypersensitivity to beta lactams Like penicillins and cephalosporins. On the other hand, Augmentin also contraindicated in patients with a previous history of augmentin associated jaundice, hepatic dysfunction.

Augmentin Warnings And Precautions

Before starting the treatment with Augmentin carefully enquiry the patient about previous hypersensitivity reactions to penicillins, cephalosporins or other allergens. Meanwhile serious and fatal hypersensitivity reaction Like.

Anaphylactoid reactions

Severe cutaneous adverse reactions

reported in patients on penicillin therapy. However these reactions are more likely to occur in individuals with a history of penicillin hypersensitivity. If an allergic reaction appear than augmentin therapy should disconnect immediately and appropriate alternative therapy should instituted.

Augmentin Over Dosage

Above all Augmentin Over Dosage effects shows Gastrointestinal symptoms. And disturbance of the fluid and electrolyte balances may evident. On the other hand Gastrointestinal symptoms may be treated symptomatically with attention to the water electrolyte balance. However, Amoxycillin crystalluria in some cases leading to renal failure has observed. In short Augmentin Dosage can be removed from the circulation by haemodialysis.

Augmentin Composition

375mg Augmentin Tablets: <—-> Each Tablet Contains 250 mg Amoxycillin and 125 mg Clavulanic acid

625mg Augmentin Tablets: <—–> Each Tablet Contains 500mg Amoxycillin and 125mg Clavulanic acid

Augmentin 1 g Tablets <———> Each Tablet Contains 875mg Amoxicillin and 125mg clavulanic acid

Augmentin 156.25mg suspension <—-> Each 5ml contains 125mg Amoxycillin, 31.25mg clavulanic acid

312.50mg Augmentin suspension<—> 5ml contain 250mg Amoxycillin, 62.50mg clavulanic acid.

Augmentin Storage Guide

In Short Store below 25 C temperature. Meanwhile Protect from sun light and moisture. Most importantly always remember to keep Augmentin Injection, Syrup, Tablets out of the reach of your small children as it may harm their health.

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Augmentin Tablets Use, Dosage Side Effects

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