Matt Drudge issued a rare tweet Wednesday imploring Oprah Winfrey to launch a presidential bid against President Trump in 2020 after the talk-show star indicated she had reconsidered whether she could be president.

"Trump vs Oprah would be the most epic race in American history. MAKE THIS HAPPEN..." Drudge, the founder of the conservative Drudge Report, wrote in a tweet to his nearly 500,000 followers.

ADVERTISEMENT

The "Queen of All Media" had suggested that Trump made her rethink whether she could win a presidential race.

"Have you ever thought that, given the popularity you have — we haven’t broken the glass ceiling yet for women — that you could actually run for president and actually be elected?" Bloomberg Media's David Rubenstein asked Oprah in an interview.

Winfrey paused before answering, prompting laughter from the audience.

"I never considered the question, even a possibility,” she began, before suggesting the question made her reconsider the idea. "I just thought, 'Oh... oh?'"

"Because, it’s clear you don’t need government experience to be elected president of the United States," Rubenstein continued.

"That’s what I thought," Winfrey responded. "I thought, 'oh gee, I don’t have the experience, I don’t know enough'... And now I’m thinking — Oh."

Winfrey said during an appearance on "The Late Show with Stephen Colbert" in January that she would never run for president.

“Is there any other charismatic African-American woman that both sides of the political aisle really love?” Colbert asked after a reference to Michelle Obama Michelle LeVaughn Robinson ObamaBiden courts veterans amid fallout from Trump military controversies The Hill's Campaign Report: Trump's rally risk | Biden ramps up legal team | Biden hits Trump over climate policy Jill Biden's boots latest fashion choice to encourage 'vote' MORE, prompting applause from the show's audience.

“Never,” Winfrey said. “No, no, it’s not my thing.”

Meanwhile, Trump has in years past floated Oprah as his own potential running mate, saying in 2015, "I think we'd win easily."