Iranian Supreme Leader Ayatollah Ali Khamenei called for the destruction of Israel over the weekend, stating that the “barbaric” Jewish state “has no cure but to be annihilated.”

In a tirade posted on Twitter Saturday night, using the hashtag #handsoffalaqsa, in reference to the recent tensions on the Temple Mount, the Iranian religious leader also reiterated his appeal to arm the Palestinians in the West Bank.

“This barbaric, wolflike & infanticidal regime of #Israel which spares no crime has no cure but to be annihilated,” Khamenei wrote.

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“West Bank should be armed just like #Gaza. Friends of Palestine should do their best to arm People in West Bank.”

The Iranian supreme leader first called to supply weapons to Palestinians in the West Bank in July, during the summer’s 50-day conflict.

This barbaric, wolflike & infanticidal regime of #Israel which spares no crime has no cure but to be annihilated. 7/23/14#HandsOffAlAqsa — Khamenei.ir (@khamenei_ir) November 8, 2014

In late August, Iran said it was stepping up efforts to arm West Bank Palestinians for battle against Israel, with Basij militia chief Mohammad Reza Naqdi saying the move would lead to Israel’s annihilation, Iran’s Fars news agency reported.

“Arming the West Bank has started and weapons will be supplied to the people of this region,” Naqdi, who heads the nationwide paramilitary network, said.

“The Zionists should know that the next war won’t be confined to the present borders and the Mujahedeen will push them back,” he added. Naqdi claimed that much of Hamas’s arsenal, training and technical knowhow in the recent conflict with Israel was supplied by Iran.

AP, AFP contributed to this report.