From the East Coast to the West, celebrities are speaking out to fight for women's rights and call for an end to sexual assault this weekend.

Natalie Portman led the front blasting the 'still free' disgraced Hollywood executive Harvey Weinstein at Variety Magazine's Power of Women luncheon in Beverly Hills on Friday.

During her 15-minute speech she condemned movie mogul Weinstein, who's been accused of rape by multiple women in the industry, for walking 'free' because 'our culture protects the perpetrators of sexual violence, not its victims.'

She also addressed the under-representation of women in all industries and commended the Time's Up movement saying: 'Be embarrassed if everyone in your workplace looks like you'.

Natalie Portman blasted disgraced movie mogul Harvey Weinstein during a powerful 15-minute speech at Variety Magazine's Power of Women luncheon in Beverly Hills on Friday

Black-ish Jenifer Lewis also delivered a speech condemning the confirmation of Judge Brett Kavanaugh and saying both President Donald Trump and Kanye West are 'mentally ill'

George Clooney introduced himself as 'Amal's husband' touched on a growing sense of xenophobia, fear of immigrants, and fear of strong women at the luncheon on Friday

He introduced student activist Emma Gonzalez to the stage to talk about March for Our Lives. She survived the February 2018 shooting at her school Stoneman Douglas High School

Gonzalez wiped away tears as she spoke. Pictured sharing a hug with comedian Jenifer Lewis after her speech on Friday at the Beverly Wilshire Hotel

She noted how the Time's Up defense fund has so far served more than 3,500 people from 'workers at McDonald's to prison guards to military personnel to women in our own industry who have faced gender-based harassment, coercion and assault.'

Following Portman, Black-ish Jenifer Lewis took the mic to blast Judge Brett Kavanaugh who has been accused of sexual assault by multiple women, and to condemn Trump's meeting with rapper Kanye West.

'We, as women, do not apologize to Kavanaugh. Let that go on the record,' Lewis said at the luncheon.

'I have bipolar disorder myself. I know what mania looks like. I know that the man in the highest office, and Kanye West, and probably several others who surround him, are mentally ill,' she added.

In her comedic speech she joked that she received a phone call from Melania Trump who complained about being 'the most bullied person in the world'. Then she received a call from Senator Lindsey Graham who said 'he was a single white man and he would not be silent' to which she replied 'as a single black woman, shut the f*** up'. Lastly she joked she got a phone call from Kanye West, a call she simply hung up.

Also present at the luncheon was student activist Emma Gonzalez who survived the February 2018 shooting at Stoneman Douglas High School in Parkland Florida.

The eighteen-year-old received a standing ovation as she was welcomed to the stand by George Clooney, who announced himself as 'Amal's husband'.

Gonzalez wiped away tears as she advocated for March for Our Lives.

'You know that you are forces to be reckoned with. You can and have inspired peace and understanding and most importantly right now, you can inspire your audience to vote. Now more than ever, women need to continue to rise up,' she said.

Emmy-winner screenwriter and actress Lena Waithe also took to the podium to speak on The Trevor Project, a nonprofit focused on suicide prevention about the LGBTQ community. Waithe pictured above with Natalie Portman

Actress and comedian Tiffany Haddish was one of the many celebrities to attend the Variety's Power of Women event on Friday, nearly a year after Harvey Weinstein was accused of sexual misconduct in bombshell articles by the New York Times and the New Yorker

Actress Regina King also spoke at the event supporting the I Have a Dream Foundation

Jane the Virgin actress Gina Rodriguez made a glowing entrance to the event held at the Beverly Wilshire hotel in Beverly Hills on Friday

#MeToo founder Tarana Burke attended the star-studded event helped nearly exactly a year after the fall of Harvey Weinstein

Clooney also shared a speech touching on xenophobia, the nation's fear of immigrants, and the fear of strong women permeating American society.

'Are we really scared of all the things that actually make America great? And if the answer is yes, then we'll have history to answer to. After all the jokes, and insults, and reality show frenzy, what will be remembered, what will stand the test of time is holding responsible these wolves in wolves' clothing,' he said.

Emmy-winner screenwriter and actress Lena Waithe also took to the podium to speak on The Trevor Project, a nonprofit focused on suicide prevention about the LGBTQ community.

'I've befriended so many women I probably would have never even met or had a reason to speak to, and I can't remember a time in this industry when women have huddled together. We've all gotten on the same page,' Waithe said.

'I wish it didn't take something so tragic to bring us together. I wish trauma in the workplace and sometimes at home wasn't the thing we had in common. Luckily we have refused to be victims. Luckily we've refused to be silent. Luckily we've decided to rise up and scream at the top of our lungs and become a force of rebels who won't be treated like second class citizens,' she said.

The magazine's luncheon was held almost exactly a year after the bombshell New York Times and New Yorker articles were published detailing the sexual misconduct allegations against movie mogul Weinstein by dozens of women.

As celebrities rallied on the West Coast for women's rights, on the East Coast Amal Clooney and Serena Williams were also speaking to thousands at the Pennsylvania Conference for Women.

Across the country on the East Coast, Amal Clooney made a moving speech criticizing Trump for mocking Christine Blasey Ford, who testified before the Senate against Judge Brett Kavanaugh earlier this month

Survivors matter: In her speech she said 'The president of a country should not publicly ridicule a women who courageously comes forward to allege abuse'

Serena Williams also spoke at the Pennsylvania Conference for Women on Friday and critiqued how mothers are treated in healthcare system

She reflected on her experience giving birth to her baby Alexis Olympia Ohanian. During her delivery she suffered several complications including blood clots in her lungs.

At the conference Amal slammed President Donald Trump for mocking Christine Blasey Ford after she took a stand before the Senate Judiciary Committee and detailed how Judge Brett Kavanaugh allegedly sexually assaulted her back in the summer of 1982.

'Survivors in any country deserve the chance to look their abusers in the eye and for history to record what has happened to them. That means the president of a country should not publicly ridicule a women who courageously comes forward to allege abuse,' she said to the conference attendees Friday morning.

'And it means the leader of the Senate should not assure constituents that he would "plow right through" her testimony,' she added.

Tennis legend Serena Williams used her platform to critique how mothers are treated in today's healthcare system, reflecting on her own delivery of baby Alexis Olympia Ohanian in which she suffered several complications including blood clots in her lungs.

'In this country that's supposed to be so technology-advanced, why are we treating our mothers like this? I was really fortunate because I had an opportunity for my voice to be heard. I had a wonderful female doctor who listened to me. There are so many women who were not being listened to. It's really unacceptable,' the champion said.

'I always have these insecurities that I’m not good enough as a mom. We all go through these different emotions that people don’t really feel comfortable talking about. I think we should. We should talk about the things that make us uncomfortable,' she added.