An explosion at a pesticide plant in eastern China has killed 47 people and injured more than 600, state media said on Friday, the latest casualties in a series of industrial accidents that has angered the public.

The blast occurred on Thursday at the Chenjiagang Industrial Park in the city of Yancheng, in Jiangsu province, and the fire was finally brought under control at 3.00 a.m. on Friday (1900 GMT), state television said.

Survivors were taken to 16 hospitals with 640 people being treated for injuries. Thirty-two of them were critically injured, it said.

The fire at a plant owned by the Tianjiayi Chemical Company spread to neighboring factories. Children at a kindergarten in the vicinity were also injured in the blast, media reported.

The cause of the explosion was under investigation, but the company - which produces more than 30 organic chemical compounds, some of which are highly flammable - has been cited and fined for work safety violations in the past, the China Daily said.

President Xi Jinping, who is in Italy on a state visit, ordered all-out efforts to care for the injured and to “earnestly maintain social stability”, state television said.

Authorities must step up action to prevent such incidents from happening and find out the cause of the blast as quickly as possible, Xi added.