Vice President Mike Pence Michael (Mike) Richard PenceGOP short of votes on Trump's controversial Fed pick Pence seeks to boost Daines in critical Montana Senate race The Hill's Campaign Report: Trump's rally risk | Biden ramps up legal team | Biden hits Trump over climate policy MORE on Tuesday praised Education Secretary Betsy DeVos during her swearing-in ceremony, calling his tie-breaker vote to confirm her the "easiest vote I ever cast."

"Never before has a vice president been called upon to cast a tie-breaking vote for a Cabinet nominee. When I cast my first vote in the United States Senate though, I wasn't just voting for you," Pence said during the ceremony.

"Having seen your devotion to improving the quality of education for some of our most vulnerable children across the nation, for so many years, I was also casting a vote for America's children. And I can tell you, my vote for Betsy DeVos was the easiest vote I ever cast."

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During the ceremony, Pence said DeVos grew up giving back to her community.

He said she and her family have devoted their time and talent to making sure every child in the country has an opportunity to a better life and a quality education.

"In Betsy DeVos," Pence said, "I truly believe our country will have a secretary of education who is already one of the foremost advocates for children in the United States."

The Senate on Tuesday confirmed DeVos to lead the Department of Education. Pence cast the deciding vote, breaking a 50-50 tie after Sens. Susan Collins Susan Margaret CollinsThe Hill's Campaign Report: Biden asks if public can trust vaccine from Trump ahead of Election Day | Oklahoma health officials raised red flags before Trump rally Gideon leads Collins by 12 points in Maine Senate race: poll Senate leaders quash talk of rank-and-file COVID-19 deal MORE (Maine) and Lisa Murkowski Lisa Ann MurkowskiGOP ramps up attacks on Democrats over talk of nixing filibuster OVERNIGHT ENERGY: House Democrats tee up vote on climate-focused energy bill next week | EPA reappoints controversial leader to air quality advisory committee | Coronavirus creates delay in Pentagon research for alternative to 'forever chemicals' House Democrats tee up vote on climate-focused energy bill next week MORE (Alaska) became the first Republican senators to oppose a Trump cabinet pick, joining all Democrats.

The last time a vice president broke a tie in the Senate was 2008, when then-Vice President Dick Cheney voted on tax legislation.