By Brooke Borel

Later this year, the U.S. Department of Agriculture may approve the Arctic Granny and Arctic Golden, the first genetically modified apples to hit the market. Although it will probably be another two years before the non-browning fruits appears in stores, at least one producer is already scrambling to label its apples GMO-free.

The looming apple campaign is just the latest salvo in the ongoing war over genetically modified organisms (GMOs)—one that’s grown increasingly contentious. Over the past decade, the controversy surrounding GMOs has sparked worldwide riots and the vandalism of crops in Oregon, the United Kingdom, Australia, and the Philippines. In May, the governor of Vermont signed a law that will likely make it the first U.S. state to require labels for genetically engineered ingredients; more than 50 nations already mandate them. Vermont State Senator David Zuckerman told Democracy Now!, “As consumers, we are guinea pigs, because we really don’t understand the ramifications.”

But the truth is, GMOs have been studied intensively, and they look a lot more prosaic than the hype contends. To make Arctic apples, biologists took genes from Granny Smith and Golden Delicious varieties, modified them to suppress the enzyme that causes browning, and reinserted them in the leaf tissue. It’s a lot more accurate than traditional methods, which involve breeders hand-pollinating blossoms in hopes of producing fruit with the desired trait. Biologists also introduce genes to make plants pest- and herbicide-resistant; those traits dominate the more than 430 million acres of GMO crops that have already been planted globally. Scientists are working on varieties that survive disease, drought, and flood.

So what, exactly, do consumers have to fear? To find out, Popular Science chose 10 of the most common claims about GMOs and interviewed nearly a dozen scientists. Their collective answer: not much at all.

1) Claim: Genetic engineering is a radical technology.

Humans have been manipulating the genes of crops for millennia by selectively breeding plants with desirable traits. (A perfect example: the thousands of apple varieties.) Virtually all of our food crops have been genetically modified in some way. In that sense, GMOs are not radical at all. But the technique does differ dramatically from traditional plant breeding.

Here’s how it works: Scientists extract a bit of DNA from an organism, modify or make copies of it, and incorporate it into the genome of the same species or a second one. They do this by either using bacteria to deliver the new genetic material, or by shooting tiny DNA-coated metal pellets into plant cells with a gene gun. While scientists can’t control exactly where the foreign DNA will land, they can repeat the experiment until they get a genome with the right information in the right place.

That process allows for greater precision. “With GMOs, we know the genetic information we are using, we know where it goes in the genome, and we can see if it is near an allergen or a toxin or if it is going to turn [another gene] off,” says Peggy G. Lemaux, a plant biologist at the University of California, Berkeley. “That is not true when you cross widely different varieties in traditional breeding.”

2) Claim: GMOs are too new for us to know if they are dangerous.

It depends on how you define new. Genetically engineered plants first appeared in the lab about 30 years ago and became a commercial product in 1994. Since then, more than 1,700 peer-reviewed safety studies have been published, including five lengthy reports from the National Research Council, that focus on human health and the environment. The scientific consensus is that existing GMOs are no more or less risky than conventional crops.

3) Claim: Farmers can’t replant genetically modified seeds.

So-called terminator genes, which can make seeds sterile, never made it out of the patent office in the 1990s. Seed companies do require farmers to sign agreements that prohibit replanting in order to ensure annual sales, but Kent Bradford, a plant scientist at the University of California, Davis, says large-scale commercial growers typically don’t save seeds anyway. Corn is a hybrid of two lines from the same species, so its seeds won’t pass on the right traits to the next generation. Cotton and soy seeds could be saved, but most farmers don’t bother. “The quality deteriorates—they get weeds and so on—and it’s not a profitable practice,” Bradford says.

4) Claim: We don’t need GMOs—there are other ways to feed the world.

GMOs alone probably won’t solve the planet’s food problems. But with climate change and population growth threatening food supplies, genetically modified crops could significantly boost crop output. “GMOs are just one tool to make sure the world is food-secure when we add two billion more people by 2050,” says Pedro Sanchez, director of the Agriculture and Food Security Center at Columbia University’s Earth Institute. “It’s not the only answer, and it is not essential, but it is certainly one good thing in our arsenal.”

5) Claim: GMOs cause allergies, cancer, and other health problems.

Many people worry that genetic engineering introduces hazardous proteins, particularly allergens and toxins, into the food chain. It’s a reasonable concern: Theoretically, it’s possible for a new gene to express a protein that provokes an immune response. That’s why biotech companies consult with the Food and Drug Administration about potential GMO foods and perform extensive allergy and toxicity testing. Those tests are voluntary but commonplace; if they’re not done, the FDA can block the products.

One frequently cited study, published in 2012 by researchers from the University of Caen in France, claimed that one of Monsanto’s corn GMOs caused tumors in lab rats. But the study was widely discredited because of faulty test methods, and the journal retracted it in 2013. More recently, researchers from the University of Perugia in Italy published a review of 1,783 GMO safety tests; 770 examined the health impact on humans or animals. They found no evidence that the foods are dangerous.

6) Claim: All research on GMOs has been funded by Big Ag.

This simply isn’t true. Over the past decade, hundreds of independent researchers have published peer-reviewed safety studies. At least a dozen medical and scientific groups worldwide, including the World Health Organization and the American Association for the Advancement of Science, have stated that the GMOs currently approved for market are safe.