Paul Allen, a co-founder of Microsoft and owner of the NFL’s Seattle Seahawks and NBA’s Portland Trail Blazers, has died at 65 from complications of non-Hodgkin lymphoma.

His family made the announcement in a statement Monday through his sister Jody Allen.

“My brother was a remarkable individual on every level. While most knew Paul Allen as a technologist and philanthropist, for us he was a much loved brother and uncle, and an exceptional friend. Paul’s family and friends were blessed to experience his wit, warmth, his generosity and deep concern. For all the demands on his schedule, there was always time for family and friends. At this time of loss and grief for us – and so many others – we are profoundly grateful for the care and concern he demonstrated every day.”

Allen’s second bout with cancer

Allen announced on Oct. 1 that the cancer he had defeated in 2009 had returned.

“I’ve begun treatment & my doctors are optimistic that I will see a good result,” Allen posted on Twitter. “Appreciate the support I’ve received & count on it as I fight this challenge.”

View photos Paul Allen has died at 65 due to complications from non-Hodgkin’s lymphoma, his family announced on Monday. (Getty) More

Microsoft responds to Allen’s death

Microsoft CEO Satya Nadella released a statement shortly after the news of his death.

Paul Allen’s contributions to our company, our industry and to our community are indispensable. As co-founder of Microsoft, in his own quest and persistent way, he created magical products, experiences and institutions, and in doing so, he changed the world. I have learned so much from him – his inquisitiveness, curiosity and push for high standards is something that will continue to inspire me and all of us at Microsoft. Our hearts are with Paul’s family and loved ones. Rest in peace.

Allen co-founded Microsoft alongside Bill Gates in 1975 in Albuquerque, New Mexico. He left the company in 1983 after his initial cancer diagnosis and a deteriorating relationship with Gates but remained a significant shareholder, which led to his vast wealth.

He used part of his fortune to purchase the Trail Blazers in 1988 and the Seahawks in 1997.

Allen’s wealth, philanthropy

Listed by Forbes as the world’s 21st wealthiest man worth $21.3 billion, Allen never married or had children. He donated more than $2 billion during his lifetime, according to Forbes, and announced in 2010 that intended to leave the bulk of his fortune to charity upon his death.

Sports Business Radio reports that Jody has no interest in ownership of the Seahawks and Blazers and anticipates that the teams will be put up for sale by Allen’s estate.

View photos A rabid fanbase and the 12th man flag became staples of the Seahawks during the Paul Allen era. (Getty) More

Allen saved Seahawks in Seattle

Allen is credited for saving the Seahawks in Seattle when he took over the team in 1996. In February of that year, then-owner Ken Behring announced plans to move the franchise to Anaheim, California. The club had mostly floundered since being founded in 1976 and had just finished a sixth consecutive losing season.

King County sued and forced a temporary block of the move while seeking potential new ownership. Allen, a Seattle native and already the owner of the Blazers was the best and only option, according to Fox 13. He agreed to purchase the team for $200 million.

“Sports really brings a community together,” Allen wrote in his memoir of the purchase. “Given my long history with this community, I felt it would be a great thing to keep the team in Seattle.”

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