The Democratic National Committee (DNC) on Saturday said it launched a digital advertisement effort against five Senate Republicans it argues caused the government shutdown.

The campaign targets GOP Sens. Lisa Murkowski Lisa Ann MurkowskiMomentum growing among Republicans for Supreme Court vote before Election Day Collins: President elected Nov. 3 should fill Supreme Court vacancy Barrett seen as a front-runner for Trump Supreme Court pick MORE (Alaska), Dean Heller Dean Arthur HellerOn The Trail: Democrats plan to hammer Trump on Social Security, Medicare Lobbying World Democrats spend big to put Senate in play MORE (Nev.), Ted Cruz Rafael (Ted) Edward CruzVideo of Lindsey Graham arguing against nominating a Supreme Court justice in an election year goes viral Sunday shows preview: Justice Ginsburg dies, sparking partisan battle over vacancy before election Democrat on Graham video urging people to 'use my words against me': 'Done' MORE (Texas), Susan Collins Susan Margaret CollinsJeff Flake: Republicans 'should hold the same position' on SCOTUS vacancy as 2016 Trump supporters chant 'Fill that seat' at North Carolina rally Momentum growing among Republicans for Supreme Court vote before Election Day MORE (Maine) and Bob Corker Robert (Bob) Phillips CorkerHas Congress captured Russia policy? Tennessee primary battle turns nasty for Republicans Cheney clashes with Trump MORE (Tenn.). Both Heller and Cruz are up for reelection.

“Republicans failed to take care of veterans, provide children with long-term access to health care, fight the opioid crisis and protect Dreamers,” Sabrina Singh, the committee’s deputy communications director, said in a statement.

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“The DNC will be launching a new digital ad campaign to hold Senate Republicans accountable for their failure of leadership and the DNC is urging voters across the country to call on their Senators and demand that they do their jobs.”

While Corker is retiring when his current term ends, and Murkowski and Collins are not up for reelection for several years, both Heller and Cruz are facing the DNC attack as they prepare to run for reelection.

Heller’s home state of Nevada went for Democrat Hillary Clinton Hillary Diane Rodham ClintonJeff Flake: Republicans 'should hold the same position' on SCOTUS vacancy as 2016 Momentum growing among Republicans for Supreme Court vote before Election Day Warning signs flash for Lindsey Graham in South Carolina MORE in the 2016 election by 2 points, while President Trump Donald John TrumpUS reimposes UN sanctions on Iran amid increasing tensions Jeff Flake: Republicans 'should hold the same position' on SCOTUS vacancy as 2016 Trump supporters chant 'Fill that seat' at North Carolina rally MORE won Texas by 9 points.

Both parties argue the other is responsible for the government shutdown, which began at midnight when the Senate failed to pass a short-term funding bill.

The Republican National Committee has invoked the hashtag #SchumerShutdown, placing the blame on Democrats and Senate Minority Leader Charles Schumer Chuck SchumerVideo of Lindsey Graham arguing against nominating a Supreme Court justice in an election year goes viral Graham signals support for confirming a Supreme Court nominee this year Pelosi orders Capitol flags at half-staff to honor Ginsburg MORE (D-N.Y.). Democrats, meanwhile, charge that Trump is responsible for the government closure.

Lawmakers have spent weeks negotiations on a spending bill, to no avail, with immigration and health-care funding at the center of the talks.