The Seattle Seahawks and San Francisco 49ers enter Sunday’s Week 17 matchup with vastly different agendas.

The Seahawks enter as division champions for the third time in four years, and a win would keep their hopes of securing the NFC’s two seed alive. As it stands now, Seattle trails the Atlanta Falcons, who can wrap up the two spot with a win at home against the New Orleans Saints.

Meanwhile, Sunday marks the end of what has been a painful and tumultuous season for the Niners, which culminated with Carlos Hyde’s MCL sprain in last week’s game. The Niners are 2-13, and in the coming weeks must address their head coaching and quarterback positions in the hopes of being somewhat relevant in 2017.

Sunday will also likely be the last time we will see the Colin Kaepernick-Russell Wilson rivalry that enraptured us just a few years ago. While the matchup may not be heralded as it once was, the Niners would love to throw a wet blanket on Seattle’s postseason plans.

With that, here are four things to know about Sunday’s game.

Related A look at the Week 17 opponents for Seattle and Atlanta

Seattle on a roll

While we love to reminisce about the days when Harbaugh versus Carroll and Kaepernick versus Wilson was the talk of the NFL, it’s easy to forget that Seattle has basically owned San Francisco since 2012. Since then, the Seahawks have won eight of 10 games against the Niners, including a playoff one (2013 NFC Championship Game). Seattle has outscored San Francisco by a combined score of 239-109. The Seahawks have won six straight games against their division foe and won each of their last five meetings by at least 10 points.

Dominating on defense

The Seahawks may be just 1-3 without safety Earl Thomas, but the defense still ranks second in the league in scoring (17.9 points per game allowed). While Seattle has given up 34-plus points in two of the last three games, take comfort in the fact that it will face the league’s 27th ranked scoring defense in San Francisco (19.1 points per game). The Seahawks have held the Niners to fewer than 14 points in seven of 10 games since 2012. That trend should continue Sunday.

Second half slump

Since 2012, Russell Wilson’s first year, the Seahawks have had the NFL’s best record in the second half of the season, going 30-9. That number does a good job of masking the poor second half play of this year’s squad. Between 2012 and 2015, the Seahawks went 13-3 in the last four games of the season but are just 1-2 since Week 14 of this year. Seattle needs to turn it around if it wants to enter the postseason with momentum on its side.

Road struggles for Wilson

Despite the loss to the Cardinals in Week 16, Russell Wilson stepped up in a big way, throwing for a career-high 350 yards to go along with four touchdown passes. Wilson has been great at home this season, but on the road it’s a different story. Wilson is 7-1 at home this year, throwing for 13 touchdowns, three interceptions and posting a passer rating of 103.5. On the road, Wilson and the Seahawks are just 2-4-1, with the quarterback throwing for seven touchdowns and eight interceptions with a passer rating of 80.4. Seattle is hoping the Wilson from last week shows up help keep Seattle in contention for the two seed.