E.U. agrees to Brexit terms

Prime Minister Theresa May of Britain has the approval of the 27 other members of the European Union on a formal divorce pact from the bloc. Now she needs the support of an outspokenly unhappy British Parliament.

Mrs. May has struggled to define how closely Britain should remain tied to Continental Europe, ultimately choosing a middle path that has left many dissatisfied.

The 585-page treaty agreed to in Brussels on Sunday deals with Britain’s outstanding payments to the bloc (around $50 billion), the rights of European Union citizens in Britain and vice versa, and how to prevent physical checks on goods at the border between Northern Ireland, which is part of the United Kingdom, and Ireland, which will remain in the European Union.

• What’s next: A vote in Parliament is expected before the end of the year. Britain’s foreign secretary, Jeremy Hunt, said getting the votes to approve the plan was looking “challenging.” Here’s a look at some of the other hurdles.

A model for treating overdoses

Dayton, Ohio, had one of the highest death rates from opioid overdoses in the country in 2017.

Now, with such deaths in the area down sharply, it may be an example of how best to address an epidemic that has killed hundreds of thousands of people in the U.S. over the last decade, including nearly 50,000 last year.

The Times interviewed police and public health officials, medical workers, people recovering from opioid addiction and people who are still using heroin and other drugs about the factors that contributed to the sharp drop in mortality.

• Go deeper: This article is part of a series about the lack of access to effective opioid addiction treatment.