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For the third time this century, a new strain of coronavirus, a family of pathogens that cause respiratory illness in birds and mammals, has jumped species and infected humans. Having broken out in the city of Wuhan, the virus, likely spread through coughing and sneezing, has now sickened more than 4,500 people and killed at least 106 in China.

On Monday, The New York Times reported that five people in the United States had tested positive for the illness. But how worried should you really be? Here’s what public health experts and others are saying.