PARIS — French voters dealt a sharp setback to the far-right National Front in regional elections on Sunday, depriving the party of victory in any of the country’s 13 regions, according to projections based on exit polls.

A week after the National Front came out on top in the first round of voting, France sent a far different message, with the party losing even in a northern region where its charismatic leader, Marine Le Pen, had been widely expected to win.

The projections also showed the National Front being defeated in another of its strongest areas, the south around Nice, where Ms. Le Pen’s 26-year-old niece, Marion Maréchal Le Pen, was on the ballot.

If confirmed when the vote count is completed, the results would confound expectations that the party, with its anti-immigrant, nativist message, was on the verge of an electoral breakthrough that could have added momentum and credibility to Ms. Le Pen’s hopes of winning the presidency in 2017.