On Tuesday, Mr. Katzenberg released an email that he sent to Mr. Weinstein on Sunday and that said he was “sickened” by the allegations. “There appear to be two Harvey Weinsteins … one that I have known well, appreciated and admired and another that I have not known at all,” Mr. Katzenberg’s email said.

Robert A. Iger, Disney’s current chief executive, said in a separate statement, “Harvey Weinstein’s reported behavior is abhorrent and unacceptable, and it has no place in our society.” Disney sold Miramax in 2010 for $660 million.

The flurry of comments came five days after a New York Times investigation chronicled a hidden history of sexual harassment allegations against Mr. Weinstein, including settlements paid, often involving former employees, over three decades. On Sunday, the Weinstein Company fired him, citing “new information about misconduct by Harvey Weinstein.”

In response to the allegations, Mr. Weinstein has acknowledged that his behavior “caused a lot of pain.” But a spokeswoman, Sallie Hofmeister, also said he “unequivocally denied” any allegations of nonconsensual sex.

Disney’s purchase of Miramax included provisions that shielded Miramax from corporate interference. The Weinsteins were given the ability to “greenlight” films with budgets of tens of millions of dollars without approval from Disney. Miramax also got to retain its own chief financial officer, head of human relations and general counsel.

According to reports at the time, the brothers demanded the autonomy, arguing that their films — which would include rough-and-rowdy titles like “Pulp Fiction,” released in 1994 — could not be incubated inside a corporate environment.

While with Disney, Miramax released more than 300 movies, which generated $5 billion in North American ticket sales and tallied at least 220 Academy Award nominations and 53 wins, including best picture Oscars for “Shakespeare in Love,” “The English Patient” and “Chicago.”

But Disney also clashed bitterly with the Weinsteins, who took advantage of their autonomy to start an expensive magazine, Talk, without approval and to move forward with the political documentary “Fahrenheit 9/11” despite being told that Disney would not distribute it. At the time, executives at Disney said Miramax had hidden its financing of that film by not including it on monthly reports about films in development; Miramax officials countered that they were aboveboard.