Pep Guardiola has refused to concede the Premier League title to Chelsea despite a disappointing 0-0 home draw with Stoke City which left Antonio Conte’s league leaders with a 10 point lead at the top of the Premier League table.

The Manchester City manager gambled by resting key players John Stones, David Silva and Raheem Sterling ahead of this weekend’s FA Cup quarter-final at Middlesbrough and next week’s Champions League last 16 second leg trip to Monaco.

The tactic backfired with City only looking like breaking down Stoke after Guardiola threw on Spanish international Silva as a substitute with just under an hour gone.

“I have said before, we take it game by game,” said Guardiola of the lead held by Chelsea. “The lead is 10 points and we now have one less game.

“We’re going to see what happens in the next game and then take it game by game. When a gap is like this, you have to focus like that; not on big targets.

“The gap was big before and is still big now. But, as I said before, we have to be focused game by game because it will be tough until the end and we will see after four or five games where we are going to fight.”

Guardiola insisted that he had no regrets over his gamble to rest key players and, with City looking impressive in the FA Cup and Champions League, there was logic behind his selection.

“The priority is the next game,” said Guardiola. “And we play for the next game.

“The rotations are good when you have successful results and they are not brilliant when you miss out.

“We only have two days now and we have another (FA Cup) game - and another one away because we have never played at home in the cup this season - and we have to use all the players.

“I would like to use more players - like Fabian Delph and others. And in the last game I didn’t play Kevin De Bruyne from the beginning so we have to use all the squad in this calendar with a lot of games.