This four-part documentary uses Dan’s story to unfurl the devastation caused by the drug addiction epidemic in the United States, and skillfully shows how local and national perspectives intersect: We hear how, in his job as a pharmacist, Dan tried to talk the young, seemingly healthy people handing him prescriptions for OxyContin out of using the drug; see him stake out the office of a local doctor prescribing incredible numbers of painkillers; watch as he talks to the Drug Enforcement Administration and gives a deposition against that doctor. Even if you know the broad strokes of the opioid crisis, “The Pharmacist” is surprising and moving.

‘Horse Girl’

Starts streaming: Feb. 7

Don’t be fooled: “Horse Girl” is a much stranger and more ambitious movie than its name, conjuring up cute childhood hobbies, might suggest. In this, her screenwriting debut, Alison Brie explores the impact of her own maternal grandmother’s paranoid schizophrenia, playing a lonely but optimistic young woman who becomes increasingly paranoid and disturbed. Co-written by Jeff Baena, who also directed, the film starts like your typical indie comedy, with sweet humor and a quirky lead character who does indeed love horses and makes friendship lanyards. But as we learn more about Sarah’s life, strange things start happening and plot points become increasingly inexplicable, and reality seems to unravel. If you enjoyed Miranda July’s deep dive into a complicated, isolated woman’s psyche in her novel “The First Bad Man,” be sure to give “Horse Girl” a watch.

‘To All the Boys: P.S. I Still Love You’

Starts streaming: Feb. 12

In this sequel to 2018’s “To All the Boys I’ve Loved Before,” perhaps Netflix’s most successful foray into teen rom-coms, Lara Jean (Lana Condor) finally has a boyfriend, the human puppy Peter (Noah Centineo). But, much to her dismay, it turns out this is where the complications really begin, as we discover what happened to the love letter Lara Jean wrote to John, her middle school crush. The scene-stealing Anna Cathcart is back as Lara Jean’s sister, and Holland Taylor joins the cast. “P.S. I Still Love You” is based on the second book in Jenny Han’s trilogy, and a third adaptation is already in the works.

‘Gentefied’

Starts streaming: Feb. 21

“Gentefied” began life as a web series, and as a half-hour Netflix show, it’s bright and snappy, full of one-liners just begging to be made into GIFs. The 10 episodes center on Ana, Erik and Chris, Latino and Latina cousins living in the Boyle Heights neighborhood in east Los Angeles, where ballooning rents have forced the trio to fight to keep their grandfather’s taco shop open. There are some very satisfying depictions of hipster culture, like a white guy in a sombrero leading a tour of local food spots, but the show really shines when it’s investigating the fraught fault lines of gentrification and the immigrant experience: For minority art to be embraced by the white creative mainstream, is a degree of exploitation inevitable? At what point do the needs of a community supersede the legacy of individuals within that community? How much change is necessary to stay afloat on the waves of gentrification? What if living the life your parents wanted for you means rejecting them? These fraught questions crept up on me watching “Gentefied,” because I was so engrossed in the characters’ day-to-day high jinks. But when the emotional moments land, they really land.

Also arriving:

Feb. 1

“The Dirty Dozen”

“Dirty Harry”

“Driving Miss Daisy”

“Elizabeth”

“Elizabeth: The Golden Age”

“The Notebook”