The 150 year reign of the grey squirrel could come to a halt from DNA editing to ensure all future females are born infertile. Researchers at the Roslin Institute want to create gene-edited squirrels for eventual release into the wild. The genetics laboratory is renowned for its 1996 creation of Dolly the Sheep, the world’s first mammal cloned from an adult cell.

Male grey squirrels would be altered to contain a “gene drive" designed to spread relentlessly through the population. This gene would make females that inherited it sterile, while males would be unaffected to allow them to keep spreading it to ensure the population eventually dies out. One aim of the project is to save red squirrels, which are native to the UK. The population drastically dropped after the introduction of grey squirrels, which carry a red squirrel killing disease called squirrel parapox virus.

Red squirrels could make a comeback in Britain's wildlife

Red squirrels now only thrive in isolated strongholds

Red Squirrels now only survive in isolated strongholds including Anglesey, the Isle of Wight and in remote forests in northern England and parts of Scotland. The approach could also help rid Britain of invasive pests such as mink, ring-necked parakeets and muntjac deer. Bruce Whitelaw, professor of animal biotechnology at the institute, said in a journal: “A potential application of gene drives is to control invasive vertebrate pests, such as cane toads and rabbits in Australia, grey squirrels in the UK, possums in New Zealand and rodents around the globe.” He, alongside co-author Gus McFarlane, asked a team of genome engineers, population modellers, ecologists, ethicists and conservation experts to design gene drives as a “potential tool” to eradicate grey squirrels. JUST IN: Vegans could legally fight to demand £5 notes be changed after ruling

The genes of grey squirrels could be altered to wipe the species out

Mr McFarlane said: “We are investigating strategies that could humanely control the UK grey squirrel population. One is spreading female infertility.” Another possible plan is to change the sex ratio in the creatures, favouring the birth of males over females until the population becomes mostly male. Many conservationists and landowners welcome plans to eradicate the species. Grey Squirrels were imported from America in the 19th century and are seen as one of the UK’s most harmful invasive species. DONT MISS Zoo owner claims parents should not bring their children to zoo [INSIGHT]

Man-eater leopard slaughters five-year-old boy in horror attack [LATEST]

Squirrel who thinks he's Tommy Cooper wins photographer top award [UPDATE]

The laboratory working on the project is the same one that cloned Dolly the sheep

Grey squirrels are considered a pest in the UK

As well as spreading diseases, the beasts prey on songbird nests and strip bark from trees such as oak and beech, stopping them growing. The population of almost 3million dwarfs the 140,000 remaining red squirrels. Forestry Commission chairman Sir Harry Studholme told The Times: “I am aware of this project and welcome it, although it’s early days.

Wiping out the species will help the growth of broad leaf trees

“We want to regrow England’s broadleaf forests with oak and other species, but we can’t do it while these animals are around.” The European Squirrel Initiative, a charity that promotes research into conserving red squirrels, is part-funding the Roslin project. Spokesman Andrew Kednall said: “The aim would be to create a few thousand gene-edited greys and then release them so the gene spreads, slowly wiping the species out in the UK. We want to reverse the invasion.

Only 140,000 red squirrels remain in the UK

Trending