Three men embark on a road trip in search of sex. It’s the premise of many a raunch-com, but “Come as You Are” diverges in one important aspect: Its libidinous heroes are disabled. Given the extent to which male sex comedies rely on physical humor, this simple twist in Richard Wong’s charming feature recasts the genre’s formulas in an entirely new light.

The characters tick familiar boxes: Scotty (Grant Rosenmeyer), who has paraplegia, is the crass, childish one; the visually impaired Mo (Ravi Patel) is a nervous stickler for the rules; and Matt (Hayden Szeto), who uses a wheelchair, is the straight man. Despite being in their mid-20s and 30s, they’re virgins who live with overbearing parents. So when Scotty finds a Canadian brothel that caters to people with disabilities, they recruit a driver (played with lovely warmth by Gabourey Sidibe) to take them across the border.