A Brisbane Uber driver has been charged with raping a teenage girl, the second of the service's drivers to face charges in a week.

The 37-year-old man from Aspley, in the city's north, was due to front the Brisbane Magistrates Court on Friday morning.

The Uber driver, who was charged with three counts of rape earlier this month, was charged on Wednesday over the alleged rape of a teen in 2015. Credit:AP

It was alleged he raped the 16-year-old passenger in Brisbane's south on July 7, about 8.30pm.

Police said the incident was unrelated to three rape charges laid against a 47-year-old Uber driver last Friday.