Four months after scoring an official pilot pickup, Hulu's Locke and Key adaptation has found its leading lady.

British actress Frances O'Connor has been tapped to topline the highly anticipated take on the beloved Joe Hill IDW comic series.

Locke and Key is a horror/fantasy series that revolves around three siblings who, after the gruesome murder of their father, move to their ancestral home in Maine only to find the house has magical keys that give them a vast array of powers. Little do they know, a devious demon also wants the keys, and will stop at nothing to attain them.

O'Connor will play Nina Locke, the mother of the three siblings who moves the family to Maine after her husband's slaying. The role was played by Miranda Otto in the 2011 Fox pilot from Josh Friedman, Alex Kurtzman and Roberto Orci that did not move forward.

Comic book creator Hill and Cuse (Lost, Bates Motel, The Strain) are collaborating on the script for the hourlong pilot. Cuse will exec produce alongside Andy Muschietti (It), Barbara Muschietti and Lindsey Springer, who serves as head of Cuse's production company. Cuse will serve as showrunner, while Muschietti will direct the IDW Comics drama. IDW Entertainment president David Ozer and Hill also exec produce.

"We are thrilled to have the multidimensional talents of Frances O'Connor to breathe color and life into this pivotal character in our series, and along with a stellar production team in place, we have no doubt that we will be able to bring Joe Hill's creative vision to the small screen," Ozer said.

O'Connor's credits include A.I. Artificial Intelligence, Once Upon a Time, The Missing and Mansfield Park. She's repped by UTA and Wishlab.