Sen. Elizabeth Warren Elizabeth WarrenDimon: Wealth tax 'almost impossible to do' CNN's Don Lemon: 'Blow up the entire system' remark taken out of context Democrats shoot down talk of expanding Supreme Court MORE (D-Mass.) hailed the resignation of Environmental Protection Agency (EPA) head Scott Pruitt Edward (Scott) Scott PruittJuan Williams: Swamp creature at the White House Science protections must be enforceable Conspicuous by their absence from the Republican Convention MORE on Thursday, saying that he should have been fired "28 scandals ago."

"A man who doesn’t believe in climate change never should have been in charge of the Environmental Protection Agency in the first place," Warren said in a statement. "And a government official that corrupt should have been fired by the President of the United States 28 scandals ago."

The progressive firebrand's comments came hours after President Trump Donald John TrumpBiden on Trump's refusal to commit to peaceful transfer of power: 'What country are we in?' Romney: 'Unthinkable and unacceptable' to not commit to peaceful transition of power Two Louisville police officers shot amid Breonna Taylor grand jury protests MORE announced in a tweet that he had accepted Pruitt's resignation, following mounting scrutiny over the EPA chief's spending and management at the agency.

ADVERTISEMENT

Trump said Thursday that Pruitt's deputy, Andrew Wheeler, would take over the former Oklahoma attorney general's responsibilities at the EPA.

Warren blasted Wheeler's credentials as well, calling him "a longtime Washington insider and corporate lawyer who’s done the bidding of fossil fuel companies for decades."

She also railed against other Trump administration Cabinet officials, whom she said "have no business running their agencies."

"Donald Trump’s cabinet is full of people who have no business running their agencies," she said. "Betsy DeVos Elizabeth (Betsy) Dee DeVosSpecial counsel investigating DeVos for potential Hatch Act violation: report NEA president says Azar and DeVos should resign over school reopening guidance The Hill's 12:30 Report - Presented by Facebook - You might want to download TikTok now MORE at the Education Department. Steve Mnuchin at Treasury. Jeff Sessions Jefferson (Jeff) Beauregard SessionsGOP set to release controversial Biden report Trump's policies on refugees are as simple as ABCs Ocasio-Cortez, Velázquez call for convention to decide Puerto Rico status MORE at the Justice Department. Mick Mulvaney Mick MulvaneyOn The Money: House panel pulls Powell into partisan battles | New York considers hiking taxes on the rich | Treasury: Trump's payroll tax deferral won't hurt Social Security Blockchain trade group names Mick Mulvaney to board Mick Mulvaney to start hedge fund MORE and his part-time work at [the Office of Management and Budget] and the [Consumer Financial Protection Bureau]."

During his tenure at the EPA, Pruitt faced numerous allegations of poor management, conflicts of interest and spending abuses, such as his use of first- and business-class travel and allegedly having aides complete personal tasks for him and renting a Capitol Hill condo owned by the wife of an influential energy lobbyist during much of his first year in office.

In his resignation letter to Trump on Thursday, Pruitt cited "unrelenting attacks" and their impacts on his family as his reason for stepping down.

"It is extremely difficult for me to cease serving you in this role first because I count it a blessing to be serving you in any capacity, but also, because of the transformative work that is occurring,” Pruitt wrote. "However, the unrelenting attacks on me personally, my family, are unprecedented and have taken a sizable toll on all of us.”