Patriots starting center David Andrews reportedly was hospitalized with blood clots in his lungs, and is at risk of missing the entire season.

It’s unclear when the 27-year-old was admitted into the hospital, though The Boston Globe reported on Monday he had been released. The Athletic indicates Andrews won’t be ready to go once the Patriots open their season Sept. 8 against the Pittsburgh Steelers.

Andrews has started in front of Tom Brady over the past four seasons, and his absence would be a major blow to the defending Super Bowl champions’ offensive line.

New England would likely lean on 2016 sixth-round draft pick Ted Karras without Andrews in the fold.

Karras, 25, has started five games in three years with the Pats.