Lawyers for Jeffrey Epstein accuser Virginia Roberts Giuffre slammed Prince Andrew’s “hurtful” claims that a now-infamous photo showing her and the royal is fake.

In a letter dated Sept. 3 to the Duke of York obtained by The Post, attorneys Brad Edwards and David Boies said Prince Andrew’s “public denials and assertions on your part concerning our client, Virginia Giuffre, are hurtful to her.”

The photo in question was taken sometime in early 2001 at Epstein’s gal pal Ghislaine Maxwell’s London home.

Giuffre has claimed she had sex with the royal after being recruited as Epstein’s alleged sex slave as a teenager.

“While your recent press statements indicate your sincere desire to help the victims of sexual abuse, we are concerned that certain statements attributed to you (which we hope do not reflect your actual views) are quite inconsistent with a desire to deal responsibly with the serious allegations that have been made,” the lawyers wrote in the Tuesday letter.

“We now see, for instance, a troubling assertion attributed to you that a well-documented photograph depicting you, Virginia Roberts Giuffre, and Ghislaine Maxwell in each other’s company is a ‘fake.’ ”

A source close to Prince Andrew has insisted that the photo appears doctored because the royal’s finger’s are “much chubbier” in real life.

The prince has denied Giuffre’s claims.

In the letter to Prince Andrew, Giuffre’s lawyers also renewed an effort to meet with him.

“In the past, in light of similar denials, we requested an interview with you during which lawyers representing various victims of Mr. Epstein, including lawyers representing Ms. Giuffre, would ask you questions about your relationship with Mr. Epstein,” they wrote.

“This would, of course, allow you to fully respond in a dignified manner and appropriate setting that would, we believe, clarify the record for everyone’s benefit, including your own,” the letter read.

The lawyers noted how “counsel in related litigation delivered correspondence to you years ago asking for an opportunity to discuss the circumstances surrounding this long-held photograph.”

“We were puzzled, and we must admit, disappointed that you did not cooperate at that time,” the letter says. “Nevertheless, given your new attention to the subject and your pledge to cooperate, we renew our request for your cooperation.”

The attorneys wrote that they are “prepared” to have a meeting with Prince Andrew in New York or London.

Last month, Giuffre urged the Duke of York to “come clean.”