Gluten intolerance is a fairly common problem.

It is characterized by adverse reactions to gluten, a protein found in wheat, barley and rye.

Celiac disease is the most severe form of gluten intolerance.

It is an autoimmune disease that affects about 1% of the population and may lead to damage in the digestive system ( 1 , 2 ).

However, 0.5–13% of people may also have non-celiac gluten sensitivity, a milder form of gluten intolerance that can still cause problems ( 3 , 4 ).

Both forms of gluten intolerance can cause widespread symptoms, many of which have nothing to do with digestion.

Here are the 14 main signs and symptoms of gluten intolerance.