A man has been charged after a laser pointer was aimed at a police helicopter in Melbourne's north last night.

Officers in the helicopter helped track down the laser, which was being shone from a moving car in Lindsey Street, Coburg, at about 10:00pm AEST.

Four men were arrested and a 20-year-old man from Preston was charged with interfering with conduct endangering life and possessing a prohibited weapon.

He was released on bail until a court hearing next month.

Police said an 18-year-old man from Coburg will be charged on summons with possessing a prohibited weapon.

Two other men were released without charge.

Issuing a warning over the use of laser pointers, Sergeant Greg Johnson said: "Used towards aircraft or other road users they're potentially blinding.

"Some of these things are incredibly strong and they can have potentially fatal consequences."