Cocktails & Chemo started as a blog, a place where Joe and Amanda Clark would share their personal account as a young couple facing a deadly disease. Joe was diagnosed with colon cancer when he was 28 years old and just two months before the couple would wed. They blogged about their accounts as they faced chemotherapy instead of a honeymoon and through the birth of their daughter, Mira Joey. When Joe died in 2014, Amanda felt a calling to recognize other caregivers like herself in her late husband's honor. Everything the foundation does is rooted in Joe's message to, "Live Loud. Love Deep. Cry Hard & Take More Pictures."