The US has denied a claim by the Syrian army that American-led coalition jets launched an air strike that hit an Islamic State chemical weapons supply, killing "hundreds including many civilians".

The accusation follows a week after Bashar al-Assad's government was accused of launching its own poison gas attack on Syrian civilians in Idlib province.

A statement on behalf of the Syrian army said the bombing at around 5.30pm local time (3.30pm BST) on Wednesday in the eastern Deir al-Zor province hit the terror group’s stockpile, without giving details of which toxic substance it might be.

But US Air Force Colonel John Dorrian, a spokesman for the America-led coalition, said it had carried out no air strikes in that area at the time.

"The Syrian claim is incorrect," he told Reuters, accusing the regime of deliberately spreading "misinformation".

U.S. airstrikes on Syria, explained

Syrian state-owned news agency Sana reported the air strike, on the village of Hatla, as a “white cloud that became yellow as a result of the explosion of a huge store that includes a large amount of toxic materials”.

There has been no independent confirmation of the alleged attack by the US-led coalition, which has operated in the skies above Syria since 2014 and includes British, French and German contributions.

The incident proved that Isis and al Qaeda-linked militants "possess chemical weapons", a statement by the army aired by Syrian state TV said.

It added that many died from suffocation after inhaling the noxious gases.

The claim will likely be viewed by observers of the Syrian regime as an attempt to divert attention away from the alleged chemical attack by Damascus on its own people.

Rex Tillerson: US have "low level of trust" with Russia

Mr Assad has been warned by the international community, including US Secretary of State Rex Tillerson, that the attack on Khan Sheikhoun, if proven to have been authorised by the government, could amount to a war crime.

Syria and its ally Russia deny Damascus carried out any such chemical attack. Moscow has said the poison gas in that incident last week was linked to rebel groups.

The toxic gas attack on 4 April, which killed scores of people including children, prompted a U.S. cruise missile strike on a Syrian air base.

Samples taken from the poison gas site in Idlib tested positive for the nerve agent sarin, the British delegation at the Organisation for the Prohibition of Chemical Weapons (OPCW) said on Thursday.

The UK result confirmed earlier testing by Turkish authorities that concluded that sarin had been used for the first time on a large scale in Syria's civil war since 2013.

In Pictures: The crisis unfolding in Syria Show all 30 1 /30 In Pictures: The crisis unfolding in Syria In Pictures: The crisis unfolding in Syria A Syrian family arrives at a checkpoint, manned by pro-government forces, at the al-Hawoz street roundabout, after leaving Aleppo's eastern neighbourhoods Getty In Pictures: The crisis unfolding in Syria A Syrian woman, fleeing violence in the restive Bustan al-Qasr neighbourhood, reacts as she stands with her children in Aleppo's Fardos neighbourhood, after regime troops retook the area from rebel fighters Getty In Pictures: The crisis unfolding in Syria Syrian pro-regime fighters, gesture as they drive past resident fleeing violence in the restive Bustan al-Qasr neighbourhood, in Aleppo's Fardos neighbourhood Getty In Pictures: The crisis unfolding in Syria Syrian rebels withdrew from six more neighbourhoods in their one-time bastion of east Aleppo in the face of advancing government troops, the Syrian Observatory for Human Rights said Getty In Pictures: The crisis unfolding in Syria Syrian rebels withdrew from six more neighbourhoods in their one-time bastion of east Aleppo in the face of advancing government troops, the Syrian Observatory for Human Rights said Getty In Pictures: The crisis unfolding in Syria Syrian residents, fleeing violence in the restive Bustan al-Qasr neighbourhood, arrive in Aleppo's Fardos neighbourhood , after regime troops retook the area from rebel fighters Getty In Pictures: The crisis unfolding in Syria Syrian pro-regime fighters, gesture as they drive past residents fleeing violence in the restive Bustan al-Qasr neighbourhood, in Aleppo's Fardos neighbourhood Getty In Pictures: The crisis unfolding in Syria Syrian residents, fleeing violence in the restive Bustan al-Qasr neighbourhood, arrive in Aleppo's Fardos neighbourhood, after regime troops retook the area from rebel fighters Getty In Pictures: The crisis unfolding in Syria Syrian residents, fleeing violence in the restive Bustan al-Qasr neighbourhood, arrive in Aleppo's Fardos neighbourhood Getty In Pictures: The crisis unfolding in Syria A Syrian pro-regime fighter speaks with a child, as residents flee violence in the restive Bustan al-Qasr neighbourhood. Syrian rebels withdrew from six more neighbourhoods in their one-time bastion of east Aleppo in the face of advancing government troops AFP/Getty Images In Pictures: The crisis unfolding in Syria Smoke rises as seen from a governement-held area of Aleppo, Syria Reuters In Pictures: The crisis unfolding in Syria Syrian soldiers targeting rebels-held areas in the eastern neighborhoods in Aleppo, Syria. According to media reports, the army is now holding on 99 percent of Aleppoís eastern neighborhoods EPA In Pictures: The crisis unfolding in Syria Syrian pro-government forces patrol Aleppo's eastern al-Salihin neighbourhood after troops retook the area from rebel fighters Getty In Pictures: The crisis unfolding in Syria Syrian soldiers rest following the battle at al-Sheik Saeed neighborhood in Aleppo, Syria EPA In Pictures: The crisis unfolding in Syria A Syrian pro-government fighter walking past closed shops in the Bab al-Nasr district of Aleppo's Old City. Once renowned for its bustling souks, grand citadel and historic gates, Aleppo's Old City has been rendered virtually unrecognisable by some of the worst violence of Syria's war Getty In Pictures: The crisis unfolding in Syria The crucial battle for Aleppo entered its 'final phase' after Syrian rebels retreated into a small pocket of their former bastion in the face of new army advances. The retreat leaves opposition fighters confined to just a handful of neighbourhoods in southeast Aleppo, the largest of them Sukkari and Mashhad Getty In Pictures: The crisis unfolding in Syria Syrian civilans arrive at a checkpoint, manned by pro-government forces, at the al-Hawoz street roundabout, after leaving Aleppo's eastern neighbourhoods. Syria's government has retaken at least 85 percent of east Aleppo, which fell to rebels in 2012, since beginning its operation Getty In Pictures: The crisis unfolding in Syria Syrian civilians flee the Sukkari neighbourhood towards safer rebel-held areas in southeastern Aleppo Getty In Pictures: The crisis unfolding in Syria Syrians celebrate in the government-held Mogambo neighbourhood of the northern Syrian city of Aleppo, after rebel fighters retreated into a small pocket of their former bastion in the face of new army advances Getty In Pictures: The crisis unfolding in Syria Syrians celebrate in the government-held Mogambo neighbourhood of the northern Syrian city of Aleppo, after rebel fighters retreated into a small pocket of their former bastion in the face of new army advances. The fall of Aleppo would be the worst rebel defeat since Syria's conflict began in 2011, and leave the government in control of the country's five major cities Getty In Pictures: The crisis unfolding in Syria A Syrian refugee camp in the Bekaa Valley, Lebanon, close to the Syrian border PA wire In Pictures: The crisis unfolding in Syria Syrian refugee Aliya inside the tent where she lives with her husband and ten children in a camp in the Bekaa Valley, Lebanon, close to the Syrian border PA wire In Pictures: The crisis unfolding in Syria Syrian refugee women and children outside the entrance to their tents in the refugee camp in the Bekaa Valley, Lebanon, close to the Syrian border PA Wire In Pictures: The crisis unfolding in Syria A Syrian refugee camp in the Bekaa Valley, Lebanon, close to the Syrian border PA wire In Pictures: The crisis unfolding in Syria A Syrian refugee camp in the Bekaa Valley, Lebanon, close to the Syrian border PA Wire In Pictures: The crisis unfolding in Syria A Syrian refugee woman outside the entrance to the tent where her family live, in the refugee camp in the Bekaa Valley, Lebanon, close to the Syrian border PA wire In Pictures: The crisis unfolding in Syria A vehicle drives past a mosque at night in Idlib, Syria. Picture taken with a long exposure Reuters In Pictures: The crisis unfolding in Syria Damaged buildings stand in the rebel-controlled town of Binnish in Idlib province, Syria Reuters In Pictures: The crisis unfolding in Syria The night sky is seen through damaged windows in the rebel-controlled town of Binnish in Idlib province, Syria Reuters In Pictures: The crisis unfolding in Syria Damaged buildings stand in the rebel-controlled area of Maaret al-Numan in Idlib province, Syria Reuters