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To Deborah E. Savage, a trip to the doctor was frequently an exercise in humiliation.

For more than 15 years, Savage’s doctors doled out the same advice: You need to stop gaining weight. When Savage replied that she had tried watching her diet and exercising, only to pack on more pounds, it was clear they simply didn’t believe her. Her family was equally skeptical.

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“I would eat like my sister, and I would gain weight but she wouldn’t,” recalled Savage, a civil engineer who lives in Montgomery County, Maryland and turns 31 next month.

Savage’s inexorable weight gain, which began in middle school and resulted in obesity, was not her only problem: For years, she also struggled with eruptions of painful acne and facial hair. “These things made me feel ugly,” she said.

Last year, after Savage had trouble getting pregnant, an inability she suspected was linked to her irregular periods, she consulted a new obstetrician/gynecologist. The doctor suggested that Savage’s constellation of problems might have a single cause. But it took a second OB/GYN to conduct the proper tests, which led to a definitive diagnosis of a common – and consequential – disorder.