The Game doesn't think Kanye West shouldn't take Daz Dillinger's Crip threat lightly -- 'cause he says his brother from another color means business.

We got the Blood-affiliated MC Monday night at Ace of Diamonds and asked about Daz calling on Crips to "f*** up" Kanye on sight after re-professing his love for President Trump. Game takes a somewhat joking tone -- but also sounds serious ... watch out, Ye.

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BTW ... Eric Benet also seemed concerned for Kanye's safety in Calabasas after we told him about Daz's message. Game appears to back that sentiment here.