•Judson Brewer (Worcester, Massachusetts): For a digital therapy centered on the psychological theory of mindfulness, which will extend ideas contained in his nationally-known Craving to Quit program to opioid addiction;<br>• Kinematechs LLC (Cincinnati, Ohio): For augmented reality-based interactive coaching system resembling glasses proposed by Yong Pei and the Kinematechs team that would use motion tracking to customize a surgical patient’s physical rehabilitation routine once they arrive home from the hospital, reducing their demand for opioid painkillers. “It’s like an expert sitting right in the glasses,” Pei said in an interview.<br>• Lee Barrus (Oren, Utah): For an opioid risk assessment screening app suggested by Barrus and the team at InteraSolutions to identify patients with risk factors for opioid abuse. The idea is to enable medical professionals to flag at-risk patients earlier and direct them to alternatives to opioids for fighting pain.<br>• The Edification Project (Boston, Massachusetts): For a use of virtual reality technology focused on preventing addiction in teens and young adults, framing attitudes early to prevent opioid abuse.<br>• The University of Dayton Research Institute (Dayton, Ohio): For a neurofeedback application developed by software engineer Kelly Cashion that uses sensors to provide real-time information to patients about their brain activity, allowing them to take back control by better understanding the effects of addiction on their brains. “Some people like to play video games, or look at the sunrise. By making them do these other tasks, anything to help them distract, and by constantly measuring it, you can see what works, reinforcing it and taking back control,” said Nilesh Powar, a senior research engineer who worked with Cashion on the project.