Sorry, Bobbi Morse fans. It looks like Adrianne Palacki won't be back as the SHIELD agent any time soon.

The actress has signed on for Seth MacFarlane's new comedic drama on Fox as the female lead, reports Deadline.

She'll be playing the ex-wife of MacFarlane's character, and the newly appointed First Officer of the Orville, a "not-so-top-of-the-line exploratory ship in Earth's interstellar fleet".

Imeh Akpanudosen Getty Images

The untitled project, set 300 years in the future, follows the adventures of a motley crew of space travellers on the Orville as they face "cosmic challenges from without and within". American Dad voice actor Scott Grimes has also been cast.

Bobbi Morse and Lance Hunter (Nick Blood) were both written out last season on Agents of SHIELD with the intention of giving the characters a spin-off. However, Marvel's Most Wanted was rejected by ABC.

Imeh Akpanudosen Getty Images

Palicki's casting in Seth MacFarlane's show doesn't mean she won't ever return to Agents of SHIELD. But at this stage, it looks like she'd only have time to swing by as a guest star.

Agents of SHIELD airs on ABC.

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