An inmate tied to the US trial of the brother of Honduran President Honduran Juan Orlando Hernández was ambushed in prison and shot in the head multiple times before being hacked with a blade in Honduras.

A surveillance camera at the El Pozo maximum security prison recorded the moment on Saturday that Nery López Sanabria was attacked by several other inmates as correction officers fled.

The horrifying video showed the 37-year-old attempting to run away before he tripped and was shot in the head multiple times.

Two inmates then repeatedly stabbed López Sanabria in the back and in his leg.

Surveillance camera at a maximum security jail in Honduras captured the moment an inmate shot Nery López Sanabria on Saturday

Nery López Sanabria (left) was the alleged business partner of ex-congressman Antonio 'Tony' Hernández (right), the president's younger brother, who was found guilty of drug trafficking by a federal court in New York

The shooter then walks back towards López Sanabria and stood over him as he continued to fire his weapon, sending blood across the floor and wall.

López Sanabria was the alleged business partner of ex-congressman Antonio 'Tony' Hernández, the president's younger brother, who was found guilty of drug trafficking by a federal court in New York on October 18.

Nearly a dozen notebooks belonging to López Sanabria appeared as evidence in the trial.

His lawyer, Carlos Chajtur, accused the Honduran government of carrying out the hit. A recent petition to have López Sanabria transferred to another prison was reportedly denied.

'He was killed to have his mouth shut,' Chajtur said.

López Sanabria made headlines after he faked his death in 2016 and arranged a funeral service, all part of a plot to avoid his extradition to the United States. He was arrested in June 2018

An inmate (bottom left) kept jail security guards away while other prisoners carry out a savage attack against Nery López Sanabria

López Sanabria, also known as Magdaleno Meza Fúnez, was the target of an assassination attempt in February when an inmate was busted with a hand grenade hidden inside his anus.

He made headlines after he faked his death in 2016 and arranged a funeral service, all part of a plot to avoid his extradition to the United States.

Honduran authorities finally arrested him in June 2018 along with his wife and three other men. He was held the National Penitentiary Center for two months before he was transferred to El Pozo.

The deputy director of Honduras's Penitentiary Institute, Germán McNeil, called his killing 'a lamentable act that we will investigate to provide a detailed report.'