Sean Hannity on Thursday blasted Speaker Paul Ryan Paul Davis RyanKenosha will be a good bellwether in 2020 At indoor rally, Pence says election runs through Wisconsin Juan Williams: Breaking down the debates MORE (R-Wis.) for withholding his support from Donald Trump Donald John TrumpObama calls on Senate not to fill Ginsburg's vacancy until after election Planned Parenthood: 'The fate of our rights' depends on Ginsburg replacement Progressive group to spend M in ad campaign on Supreme Court vacancy MORE’s White House run.

"I'm not ready to support Speaker Ryan anymore," Hannity said on last night's program. "I'm thinking maybe we need a new Speaker."

In a series of earlier tweets, the Fox News host ripped Ryan hours after the Speaker said he wasn't ready to endorse the party's presumptive nominee.

@SpeakerRyan You have to be kidding me on @realDonaldTrump. Establishment out to sabotage GOP nominee, yet they betrayed the base #Pathetic — Sean Hannity (@seanhannity) May 5, 2016

Good luck with no wall, Obamacare, liberal justices, common core, more debt, refugees not vetted, and Pres. Hillary https://t.co/2G64uInQ2T — Sean Hannity (@seanhannity) May 6, 2016

Trump's final two opponents for the GOP nomination, Sen. Ted Cruz Rafael (Ted) Edward CruzSenate Republicans face tough decision on replacing Ginsburg Cruz: Trump should nominate a Supreme Court justice next week Renewed focus on Trump's Supreme Court list after Ginsburg's death MORE (R-Texas) and Ohio Gov. John Kasich, dropped out this week, but Hannity said Ryan, the highest ranking elected Republican nationally, was ignoring the will of the people.

Exactly. The Hell with what the voters think. Circular firing squad now led by @SpeakerRyan https://t.co/nXqrLYvQKk — Sean Hannity (@seanhannity) May 6, 2016

Ryan on Thursday said that he is not yet capable of supporting Trump as the Republican standard-bearer next fall.

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“To be perfectly candid with you … I’m just not ready to do that at this point,” he said on CNN’s “The Lead." "I’m not there right now.”

Trump counterpunched later that evening, commenting that he remains skeptical of Ryan’s agenda in Congress.

“Perhaps in the future we can work together and come to an agreement about what is best for the American people,” he said in a statement. "They have been treated so badly for so long that it is about time for politicians to put them first!”

Trump on Tuesday won Indiana’s GOP presidential primary, clearing the path to become the party’s presumptive presidential nominee.

The billionaire’s bruising nominating race, however, has left many Republicans swearing they will not back him heading into next November’s general election.