Hundreds of protesters gathered in Boston on Sunday to voice opposition to the Trump administration, particularly over issues of climate change.

Protesters held signs reading “Science Matters,” “Follow the Evidence” and “Climate Change is Real,” the Boston Globe reported.

Protesters also chanted “Stand up for science” in the middle of Boston’s Copley Square, with some wearing white lab coats.

The rally took place the same weekend as the American Association for the Advancement of Science annual meeting in Boston.

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Some protesters attended to criticize the confirmation of Environmental Protection Agency chief Scott Pruitt and slam the Trump administration’s stance on issues like climate change.

Some attendees also seemed to urge Trump to support the science behind vaccines.

One sign read “Got Polio? No! Thank science,” according to the Globe.

Trump has expressed skepticism over climate change, as have some of his top Cabinet members and nominees. He, along with Pruitt, have vowed to roll back many of President Obama's major environmental regulations. And he has also previously voiced doubts about the efficacy of vaccines. Trump also met with noted vaccine skeptic Robert F. Kennedy Jr.