(CNN) Sen. Elizabeth Warren will link Donald Trump's recent criticism of a federal judge to a larger indictment of the Republican Party's "full-scale assault" on the federal courts system during a speech Thursday.

The progressive senator, set to speak to the American Constitution Society, will charge Trump and top Republicans -- including House Speaker Paul Ryan and Senate Majority Leader Mitch McConnell -- with attempting to delegitimize the judiciary in order to favor "the rich and powerful," according to a preview of Warren's remarks.

"Donald Trump is a loud, nasty, thin-skinned, fraud who has never risked anything for anyone and serves nobody but himself. And that is just one of the many reasons why he will never be president of the United States," Warren will say.

Citing Trump's treatment of the federal judge overseeing the Trump University lawsuit as an example of this effort, the Massachusetts senator will say: "Judge (Gonazalo) Curiel has survived far worse than Donald Trump. He has survived actual assassination attempts. He'll have no problem surviving Trump's nasty temper tantrums."