Depression, mood swings, paranoia and many more are the symptoms we commonly associate most of our idols. Writers, painters, politicians, the most innovative men and women in history are often connected to a family background of mental disorders or are mentally ill themselves. As mentioned before mental disorders lead people to think out-of-the-box. Associate different concepts never thought before, as example when Da Vinci associated planes with birds, or Einstein with its revolutionary theory who related matter to energy. They all devoted their thoughts and work life to what they loved, what made them express their creativity. In the beginning of this essay it is said different hemispheres of the brain correspond to different aptitudes of the person, when one of those hemispheres is hyper-developed subsequently a special aptitude may be hyper-developed as well. We can surely recall the names of many writers, who were as famous for their writing as they were for their loneliness. Their works are proof of that, they often tell us how mentally tormented they feel and how the world challenges their emotions. Enclosed in their rooms or their studies they chain all their problems into a creative process that is usually some kind of self-therapy or expression of opinion. John Nash formulated The Game Theory while suffering from schizophrenia on its peak. Sá Carneiro was a lonely emotionally troubled writer who wrote his most beautiful work before he committed suicide. Virginia Woolf writing is deeply affected by her depression, as is the case of Florbela Espanca in Portugal. James Fallon, neurobiologist at the University of California-Irvine says "People with bipolar tend to be creative when they're coming out of deep depression,". When a bipolar patient's mood improves, his brain activity changes: “activity dies down in the lower part of a brain region called the frontal lobe, and flares up in a higher part of that lobe.” The same change occurs when people have bouts of creativity. While there are many doubts about how the brain functions, one thing we can be certain the most psychiatric disordered people produce the most beautiful innovative art. Let us all embrace our moments of “madness” and chain it into creativity.