MSNBC host Chris Matthews on Thursday asked Sen. Kamala Harris Kamala HarrisHundreds of lawyers from nation's oldest African American sorority join effort to fight voter suppression Biden picks up endorsement from progressive climate group 350 Action 3 reasons why Biden is misreading the politics of court packing MORE (D-Calif.) how she does not “have hatred towards white people generally" during the senator's first post-debate interview in Miami.

The question came after Harris confronted front-runner Joe Biden Joe BidenPelosi slams Trump executive order on pre-existing conditions: It 'isn't worth the paper it's signed on' Hillicon Valley: Subpoenas for Facebook, Google and Twitter on the cards | Wray rebuffs mail-in voting conspiracies | Reps. raise mass surveillance concerns Fox News poll: Biden ahead of Trump in Nevada, Pennsylvania and Ohio MORE during the debate, hitting the former vice president for his civil rights record while broaching remarks he made regarding his past work early on his career with segregationist Sens. John Eastland (D-Miss.) and Herman Talmadge (D-Ga.).

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“I have a great deal of respect for Joe Biden,” Harris told Matthews. “I do not believe he’s a racist, but his perspective on those senators was something that was hurtful and it had consequences.”

“How did you come out of that and not have hatred towards white people generally?” Matthews asked.

“Most Americans do not conduct themselves that way, and most parents don’t conduct themselves that way,” the senator responded. “So there was no need to create a broad application because of that one experience, but we cannot deny that there are many children, black children in America who have had that experience.”

According to Twitter data provided to The Hill, the Harris-Biden exchange emerged as the most tweeted #DemDebate moment of Thursday night.

Biden and Harris were also the most tweeted about Democratic candidates, also according to Twitter data, followed by Sen. Bernie Sanders Bernie SandersThe Hill's Campaign Report: Trump faces backlash after not committing to peaceful transition of power Bernie Sanders: 'This is an election between Donald Trump and democracy' The Hill's 12:30 Report: Trump stokes fears over November election outcome MORE (I-Vt.).