Typically no. Though indeed, he has recently contributed to a dramatized audio reading of the New International Version Bible called "The Bible Experience," along with Denzel Washington. Samuel L Jackson reads the parts of God.

http://www.youtube.com/watch?v=1SM4A8aa47U

But a lot more to it than that is he quite frequently stars in many category-shattering anti-Christian movies (Pulp Fiction, Jumper, Jungle Fever, Lakeview Terrace, etc) as to showing them as ignorant, mean-spirited Bible-thumpers, which really has some disappointment among many religious fans of Jackson, even some atheist ones.