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U.S. Attorney Barbara McQuade in a July 9, 2015 file photo taken after the sentencing of oncologist Farid Fata, who was sent to prison for 45 years for administering chemotherapy to patients who didn't need it. (Tanya Moutzalias | MLive file)

DETROIT -- President Donald Trump and Attorney General Jeff Sessions have ordered 46 federal prosecutors appointed by former President Barack Obama, including Detroit-based U.S. Attorney Barbara L. McQuade, to resign

McQuade, who led the prosecution of imprisoned former Detroit Mayor Kwame Kilpatrick, issued a statement late Friday, but didn't indicate definitively whether she indeed intends to submit her resignation.

"I have loved serving in this job as much as anyone has ever loved any job," McQuade said.

"It has been an incredible privilege to work alongside public servants who devote their tremendous talents to improving the quality of life in our community. I am proud to have served as U.S. Attorney in the Obama Administration."

Sarah Isgur Flores, a Justice Department spokeswoman, told the New York Times all remaining U.S. attorneys appointed during the Obama presidency were told to resign and shift control to their deputy U.S. attorneys.

Former western Michigan U.S. Attorney Patrick Miles, Jr., another Obama-appointed federal prosecutor, resigned in January as Trump took office.

McQuade, who is the first woman to head the federal prosecutor's office for the Eastern District of Michigan, was appointed in 2010.

"During her tenure, McQuade has overseen a number of significant cases," McQuade's office said in the statement, "including the conviction of former Detroit Mayor Kwame Kilpatrick and more than 30 others on public corruption charges; the conviction and life sentence of an Al-Qaeda operative for attempting to blow up an airliner over Detroit on Christmas Day in 2009 with a bomb concealed in his underwear; the conviction and 45-year sentence Dr. Farid Fata for lying to patients about having cancer so that he could bill Medicare for expensive chemotherapy treatments; the conviction and $4.3 billion fine against Volkswagen AG for cheating on emissions tests; the conviction and $1 billion fine against Takata Corp. for fraudulently concealing defective airbags; and settlements with Pittsfield Township to permit the building of an Islamic School and with the City of Sterling Heights to permit the building of a mosque under religious land use laws,"

McQuade, a married mother of four children, was born in Detroit, graduated from the University of Michigan in 1987, Michigan Law School in 1991, worked as a law clerk for U.S. District Judge Bernard A. Friedman, and worked as an adjunct professor at Detroit Mercy School of Law from 2003 to 2009.

She worked as an assistant U.S. attorney in Detroit for 12 years before being promoted to the top job.