This article has been updated. Read the obituary for John McCain, who endured five years of captivity in Vietnam and rose to the heights of power in Washington.

Senator John McCain died on Saturday, about 13 months after his office announced he had a brain tumor called a glioblastoma. The diagnosis was based on a biopsy of the tissue removed from his brain in July 2017 during surgery at the Mayo Clinic Hospital in Phoenix.

What sort of brain cancer is this?

Glioblastoma is the most aggressive type of brain tumor. It originates in the brain; it does not spread there from another part of the body. The cause is not known.

This tumor has no relation to melanoma, the skin cancer for which Mr. McCain was treated in the past.