A well-known Queensland charity will close its doors this week after assisting Brisbane's homeless for more than 10 years.

Mama Rene's in Carindale has been providing a food van service to approximately 350 people every Tuesday and Friday night.

The group has been forced to close after the group's lease on the property where they serve food from was not renewed and the charity was unable to find another location.

Pastor John Dowell told 612 ABC Community Correspondent Genevieve Robey that there are many factors currently working against them.

"Besides our lease and financial constraints, one of our primary food suppliers Food Bank Queensland is having difficulty getting food at the moment," he said.

"We have had use of a car park for many years, it is owned by Mental Health and we would arrive there each week at a set time.

"There's always a queue, a queue for hot food, a queue for tea and coffee then another line for perishable groceries and food and veggies."

Pastor Dowell says it is not only the recipients who are devastated but also the dozens of volunteers who support the cause.

"Many of the people I feed, I have been feeding for many years, and they rely heavily on our service to survive," he said.

"The volunteers are devastated too, they have put in many years and it is hard for them to let go.

"It breaks my heart to walk away."

Lack funding and support

Pastor Dowell says the group receives no government funding, with money coming from volunteers and local community groups such as Lions and Rotary.

"We did apply for grants to help us buy vehicles, but it was not enough," he said.

"We have made a safe place for people to come too. There is no sit-down meal, they stand in the dark in a line and they get a plate of food with a fork. It's not a comforting thing, people who come really need it."

He believes that within 12 months the homeless situation in Brisbane will worsen.

"I can tell you next year it is going to be a whole lot worse," he said.

"Services have dried up, there is no funding for anyone, we are the bottom of the food chain.

"What is leftover for us is usually crumbs, but even the crumbs are gone now."

A unique charity

Mama Rene's has been one of the only groups in Brisbane to provide both a hot meal and perishable items for the needy to take home with them.

Pastor Dowell says there is no-one else like them.

"No other charity is geared to do what we have done. There are many food vans taking tea and coffee and a sandwich or two but there's no-one doing what we do in the city," he said.

"We service elderly people, migrants, and young people... it is going to leave a big hole."

He says the public does not realise how many people can be affected by homelessness.

"One lady we helped had two children and she was from England. She landed on the street and had nothing and she came to the ministry and we have seen those boys turn into men," he said.

"The elderly need help too. When they lose a spouse, that cuts their benefit in half and they find themselves in poverty."