With great power, comes great responsibility — and a whole lot of drama.

According to Deadline, a breakdown in negotiations between Disney and Sony “has essentially nixed” Marvel Studios President Kevin Feige from future standalone Spider-Man films.

This news comes days after “Spider-Man: Far From Home” became Sony’s highest grossing film ever, earning $1.1 billion worldwide, and weeks since Disney and Marvel’s “Avengers: Endgame” edged out “Avatar” to become to top film of all time at the box office.

The Spider-Man movies — which have starred Tobey Maguire, Andrew Garfield and now Tom Holland — have been made by Sony’s Columbia Pictures since 1999, when the studio acquired the iconic character. That was 9 years before the Marvel Cinematic Universe kicked off with “Iron Man” and became a worldwide sensation, with Feige shepherding 23 blockbuster hits.

With the advent of the MCU, Marvel brokered an agreement with Sony that the characters could cross back and forth between the studios’ films (i.e. “Spider-Man: Homecoming” and “Avengers: Infinity War”) and both would get a small cut of the profits.

But now Deadline reports that Marvel, which is owned by Disney, recently requested to revise the deal — and divide Spider-Man profits evenly. Sony, the outlet says, flatly refused a 50/50 cut, which is why Feige would have no involvement in any upcoming Spidey sequels.

A Sony studio source tells The Post negotiations are actually ongoing and that Feige has made creative decisions on previous Sony films in which he had no producer credit, such as “Venom.”

The effects of this dispute, they say, would be minor.