FOXBOROUGH, Mass. -- From perfection to dejection.

Reigning NFL MVP Tom Brady left Sunday's game against Kansas City after being hit on the left leg, and the New England Patriots sounded pessimistic about the prognosis for the the quarterback who last year led them to a 16-0 regular season.

The two-time Super Bowl MVP, who has started 128 consecutive games, went to the turf clutching his left knee midway through the first quarter when he was hit in the pocket by Chiefs safety Bernard Pollard. After being tended to on the field, he walked off, limping, between two trainers.

"The play was not intentional," Pollard said, according to The Boston Globe. "People can call me a dirty player, you can call me whatever you want to call me, it's not a dirty play. When you have 230 pounds on your back, and you're trying to go forward, things will happen. I saw the ball was still in his hands and I tried to get to him. I tried to get up and get to him. But I couldn't get up, so I just tried to grab him. It was not an intentional play."

Coach Bill Belichick provided no information on the injury, but Pollard had a diagnosis of his own.

"He was in a lot of pain," he said. "When you hear a scream, you know that."

Brady, 31, went to the locker room and wasn't seen again on the sideline as backup Matt Cassel led the Patriots to a 17-10 victory. The two-time Super Bowl MVP was not available for comment after the game, and Belichick said he had nothing to add to the in-game announcement that it was a knee injury.

Tom Brady is hit Sunday by Chiefs safety Bernard Pollard, bottom. The Patriots announced Brady had a knee injury and he didn't return. AP Photo/Winslow Townson

"They're looking at him, doing some tests on him, so I don't have any information there," the coach said, cracking a smile as he added, "doubt anybody's interested."

Brady is scheduled for an MRI on Monday.

Although no test results had yet to be revealed, one Patriots player went so far as to tell ESPN analyst Trent Dilfer after the game, "Cassel's our quarterback for the rest of the year."

Belichick addressed the team after the win and told Cassel that if he is called upon, he will be counted on to step up and help the team.

The Patriots will bring in quarterback Chris Simms for a workout Monday. ESPN's Chris Mortensen reports the Patriots will also look at journeyman Tim Rattay. When the Patriots drafted Brady in the sixth round in 2000, the decision was between Brady and Rattay. The Patriots took Brady because he is taller (6 feet 4 to Rattay's 6 feet).

The Chiefs also lost their starting quarterback when Brodie Croyle was sacked in the third quarter. The team said he had a bruised right shoulder and he was replaced by Damon Huard.

Brady was 7-for-11 for 76 yards, completing a 28-yard pass to Randy Moss on the play in which he was injured. Moss fumbled the ball away when he was tackled; the Patriots forced Kansas City to punt, then Cassel came in for New England.

"Since I've been here and been around Tom, he's always popped back up," Cassel said. "I didn't know [how serious it was]. I just buckled my chinstrap and the guys rallied around me. I felt their support."

Cassel took over at his 2 yard-line and, after two handoffs nearly netted the Chiefs a safety, completed his first pass to Moss for a 51-yard gain. Cassel, Brady's backup for the past three years, finished the 98-yard drive with a 10-yard touchdown pass to Moss that gave New England a 7-0 lead.

"This is something I've been preparing for for a long time," said Cassel, who threw just 33 passes while backing up Heisman Trophy winners Carson Palmer and Matt Leinart at Southern Cal. "It's not something I expected to come up on opening day."

A former fourth-stringer who was the 199th overall selection in the 2000 draft, Brady himself took over at quarterback when longtime starter Drew Bledsoe sustained a life-threatening chest injury in a 2001 game against the New York Jets. Brady led the Patriots to their first NFL title that year, another in 2003 and another in 2004.

In the process, Brady has become one of the league's biggest stars and a crossover cover boy who has met the Pope and the president, dated actresses and supermodels and rewrote one of the NFL's most coveted records.

Last year, while leading New England to a 16-0 regular season, Brady set a record with 50 touchdown passes and improved his overall record as a starter to 100-27 -- the best in the Super Bowl era. The Patriots blew a chance at an unprecedented 19-0 season and a fourth NFL title with a 17-14 loss in February's Super Bowl to the New York Giants.

Brady did not play in four exhibition games this summer -- all of them Patriots losses -- while trying to recover from a right foot injury.

"He's the face of the New England Patriots, and Tom being who he is it kind of hurts, to be honest with you," said Moss, who caught 23 of Brady's TD passes in 2007, also a record. "I know the show must go on. Hopefully Matt Cassel is ready to step in. I know the team is ready to embrace him and let him lead us."

Information from The Associated Press was used in this report.