A California woman fell into a semi-comatose state after using a tainted skin scream imported from Mexico — the first such case in the US, officials announced this week.

The 47-year-old woman, of Sacramento, bought the Pond’s-labeled skin cream — used as a skin lightener and to remove spots and wrinkles — at a pharmacy in the state of Jalisco, Mexico, according to a statement on the county’s website, and local station KCRA.

It turned out that the cream was tainted with methylmercury, a substance highly toxic to humans that wasn’t added by Pond’s manufacturer, but by a third party after purchase, officials said.

The woman arrived at the emergency room with numbness in her hands and face, trouble walking and slurred speech — and her condition deteriorated over several weeks, health officials told KCRA. She was initially able to respond to verbal commands, but then became semi-comatose.

“Sacramento County Public Health urges the community to immediately stop using similar skin creams imported from Mexico due to the risk of contamination with methylmercury,” Sacramento County Public Health Officer Dr. Olivia Kasirye said in the statement. “Methylmercury is extremely dangerous to adults and children.”

The woman has been in the hospital since July, her son told KCRA. Doctors tested her cosmetic products, he said.

“When they got to the face cream is when they noticed it had a very high level of mercury,” he told the outlet.

Upon entering the nervous system, methylmercury can cause severe illness, especially in pregnant and breastfeeding women and children.

Symptoms include difficulty concentrating, memory loss, anxiety, depression, insomnia, headaches and weight loss.

Children with prolonged exposure can experience pink hands and feet, skin flaking, excessive saliva, gum disease and high blood pressure, among other symptoms.

Over the past nine years in California, more than 60 poisonings have been linked to foreign brand, unlabeled, and/or homemade skin creams containing mercurous chloride or calomel — the less hazardous form of mercury, officials said.