The song could launch as the trio's first Hot 100 leader.

Jonas Brothers' comeback single "Sucker" is aiming for a possible No. 1 debut on next week's Billboard Hot 100 chart (dated March 16).

The song would mark the sibling trio's first Hot 100 leader after it charted 16 titles in 2007-09 and one more in 2013. The act has scored two Hot 100 top 10s: "Burnin' Up" (No. 5) and "Tonight" (No. 8), both in 2008.

The Hot 100 blends weekly streaming, airplay and sales data, according to Nielsen Music.

Projecting building-week data, "Sucker," released on Republic Records, should rocket in with over 40 million U.S. streams, 25 million radio audience impressions and 80,000 downloads sold after its first full week of tracking. It debuted at No. 28 on the March 9-dated Pop Songs airplay chart following its first three days of availability; it was released, along with its official video, at midnight ET Friday, March 1. (The streaming and sales tracking weeks for the March 16-dated Hot 100 will encompass March 1-7.)

Helping power the song's likely lofty totals is consumer reaction to Jonas Brothers' week-long residency this week on CBS' The Late Late Show With James Corden, including a much-buzzed-about Carpool Karaoke ride.

"Sucker" could net the second No. 1 debut of 2019 on the Hot 100, after Ariana Grande's "7 Rings" (Feb. 2). (Grande also logged the prior such start, with "Thank U, Next" on Nov. 17.) Only one song by a group in a lead role has ever launched atop the Hot 100: Aerosmith's "I Don't Want to Miss a Thing," on Sept. 5, 1998.

While "Sucker" is the first single by Joe, Kevin and Nick Jonas as the Jonas Brothers since 2013, Nick logged the No. 7-peaking solo Hot 100 hit "Jealous" in 2015. As a member of DNCE, Joe rose to No. 9 in 2016 via the act's "Cake by the Ocean."

Also on next week's Hot 100, Cardi B and Bruno Mars are aiming to return to the top five with "Please Me." Following the March 1 premiere of its official video, the song could surge from 24.4 million streams to over 35 million. The duet debuted at No. 5 on the March 2-dated Hot 100 and dipped to No. 14 in its second week.

Highlights of next week's Hot 100 are scheduled to post on Billboard.com Monday (March 11), with all charts posting the following day.