A 12-year-old self-taught driver out looking for boys in her grandmother's car led police on a brief chase that reached 110kmh in a 60kmh zone early today.

Police were shocked to find the driver of a car they were pursuing early this morning was a 12-year-old girl.

Police from Reservoir noticed the Mitsubishi wagon driving without headlights along Mahoneys Road, Thomastown about 1.45am but when they attempted to pull the car over it accelerated away and a short pursuit ensued.