California Democratic Sen. Kamala Harris said there would be the “destruction of the Constitution” if President Donald Trump got to pick the Supreme Court justice to replace Justice Anthony Kennedy, Wednesday on MSNBC’s “Hardball with Chris Matthews.”

“We’re looking at a destruction of the Constitution of the United States as far as I can tell based on all the folks he’s been appointing thus far for lifetime appointments,” Harris told Matthews on Wednesday night. “He’s been appointing ideologues, he’s been appoint people who have refused to agree that Brown v. Board of Education is settled law.”

Harris’s comment was in response to Matthews asking her what the Supreme Court is “going to look like for the next 30 years.” (RELATED: It Only Took Jeffrey Toobin Three Hours After Justice Kennedy’s Retirement To Talk About Abortion)

“The President’s list of potential SCOTUS nominees are complete non-starters,” Harris tweeted Wednesday. “They are conservative ideologues, not mainstream jurists. We cannot and will not accept them to serve on the highest court in the land.”

The President’s list of potential SCOTUS nominees are complete non-starters. They are conservative ideologues, not mainstream jurists. We cannot and will not accept them to serve on the highest court in the land. — Kamala Harris (@SenKamalaHarris) June 27, 2018

Kennedy announced his retirement on Wednesday, leaving a possible SCOTUS pick for Trump if he can get the nomination past the Senate.

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