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This study investigated the effects of particulate matter (PM) on human skin diseases by conducting a systematic review of existing literature and performing a meta-analysis. It considered articles reporting an original effect of PM on human skin. From among 918 articles identified, 13 articles were included for further consideration after manual screening of the articles resulted in the exclusion of articles that did not contain data, review articles, editorials, and also articles in languages other than English. Random-effects models and forest plots were used to estimate the effect of PM on the skin by Meta-Disc analysis. According to people’s reports of exposure and negative skin effects (atopic dermatitis (AD), eczema, and skin aging, etc.) due to air pollution, the summary relative risk (odds ratio) of PMwas determined to be 0.99 (95% confidence interval (CI) 0.89–1.11) whereas PMwas determined to be 1.04 (95% CI 0.96–1.12). Simultaneously, there was a different extent of impact between PMand PMon atopic dermatitis (AD) for those of young age: the odds ratio of PMand PMwere 0.96 (95% CI 0.83–1.11; I= 62.7%) and 1.05 (95% CI 0.95–1.16; I= 46%), respectively. Furthermore, the results suggest an estimated increase of disease incidence per 10 μg/mPM of 1.01% (0.08–2.05) due to PMand 1.60% (0.45–2.82) due to PM. Following the results, PMand PMare associated with increased risks of human skin diseases, especially AD, whose risk is higher in infants and school children. With its smaller size and a high concentration of metals, PMis more closely related to AD in younger people, compared to PM