A South Burlington woman is dead and the man suspected of shooting her is on the run.

Police are asking for the public's help in finding Leroy Headley, 36, of South Burlington. They are calling him armed and dangerous and say he may be driving a 2017 blue Nissan Pathfinder with Vermont plates HBR 281.

South Burlington Police remained on scene late into the night at what neighbors tell us is normally a quiet street. But Thursday night, it was filled with blue flashing lights and crime scene tape.

Southview Drive was closed as police surrounded a green duplex. One of the units-- unit 10-- is the scene of a murder.

The victim's brother arrived on scene distraught. Police were able to talk to him and calm him down.

"I can only assume how difficult this is," South Burlington Police Chief Trevor Whipple said.

South Burlington Police say a man walked into a police station in Falmouth, Massachusetts, just after 6 p.m. Thursday, and said a family member of his-- Leroy Headley-- may have just committed a murder.

"He had called this gentleman in Falmouth and said that he had shot his girlfriend," Whipple said.

Police arrived at Southview Drive to find the woman shot dead in the apartment. They're not releasing her name yet or saying how long she had been there.

Now, a manhunt is underway for Headley and police are warning the public that he is armed and dangerous.

"We do not know Mr. Headley's whereabouts at this point. He is a suspect," the chief said.

The woman who lives in the other unit in the duplex said she was not home at the time and didn't know her neighbors too well.

Police told us that they were familiar with this location.

"This seems to be a very targeted crime. I don't believe, generally, there is a significant risk to the public, but if what has been reported is true, we could have a person who does have a propensity toward violence," Whipple said. "This gentleman could be very desperate."

The police presence in this neighborhood will continue through the night. Police tell us they will be here, as well as the Vermont State Police crime scene lab, which is set to arrive to take over the scene.

This is not the first time Leroy Headley has been in the news. We reported on Headley being arrested in March of last year. Police said then that Headley met two 13-year-old girls at the mall, took them to a hotel, gave them alcohol and sexually assaulted them.