Hillary Clinton Hillary Diane Rodham ClintonJeff Flake: Republicans 'should hold the same position' on SCOTUS vacancy as 2016 Momentum growing among Republicans for Supreme Court vote before Election Day Warning signs flash for Lindsey Graham in South Carolina MORE on Wednesday swatted aside a speech from Donald Trump Donald John TrumpUS reimposes UN sanctions on Iran amid increasing tensions Jeff Flake: Republicans 'should hold the same position' on SCOTUS vacancy as 2016 Trump supporters chant 'Fill that seat' at North Carolina rally MORE earlier in the day devoted to taking her down, arguing that she must have pushed her Republican rival’s buttons.

"I know Donald hates it when anyone points out how hollow his sales pitch really is. I guess my speech yesterday must have gotten under his skin, because he lashed out on Twitter with outlandish lies and conspiracy theories. He did the same in his speech today," she told supporters during an appearance in North Carolina.

ADVERTISEMENT

"Think about it, he's going after me personally because he has no answers on the substance."

Clinton stuck to her standard stump speech for most of the address, which includes small digs at Trump. But she ended with a full-on rebuke of Trump and a response to his criticism of the Clinton Foundation.

"Of course attacking a philanthropic foundation that saves and improves lives around the world — it's not a surprise that he doesn’t understand these things," she said.

"The Clinton Foundation helps poor people around the world get access to life-saving AIDS medicine. Donald Trump uses poor people around the world to produce his lines of suits and ties."

And she replayed her attacks from her Tuesday speech, which portrayed the real estate mogul as unfit to handle the economy in part because of his penchant for leveraging bankruptcy laws to his benefit.

Trump minced no words in his Wednesday address attacking Clinton, which he also used to give the impression that he has righted his ship since firing his campaign manager earlier this week.

He bashed Clinton as a "pathetic liar" and accused her of profiting off of her time as secretary of State and her husband's stint in as president.

"Hillary Clinton — who, as most people know, is a world-class liar — just look at her pathetic email and server statements, or her phony landing in Bosnia where she said she was under attack but the attack turned out to be young girls handing her flowers — a total self-serving lie," he said.

"I have always had a talent for building businesses and, importantly, creating jobs. That is a talent our country desperately needs."