DES MOINES, Iowa — Hillary Clinton is finding out what it's like to be on the long list of Democratic also-rans.

The party has, for years, discarded losing presidential candidates such as George McGovern, Walter Mondale, and Michael Dukakis, among others — to the point that they're often treated as contagious diseases, seen at best as cautionary tales about how not to campaign for the White House.

Fair or not, Clinton has, in many ways, had that dishonor bestowed on her. Having lost the 2016 election to President Trump in one of the biggest political upsets in American history, the former first lady, senator, and secretary of state, 72, is a pariah among some Democrats as the party's nominating season kicks off Monday with the Iowa caucuses.

Democratic Michigan Rep. Rashida Tlaib on Friday night, for example, booed Clinton from the stage of a campaign event for Vermont Sen. Bernie Sanders, the runner-up in the 2016 Democratic contest. Onstage in Clive, Iowa, a panel discussion Tlaib was participating in turned to Clinton's recent comments bashing the socialist White House candidate, 78.

"You all know I can't be quiet. No, we're gonna boo," Tlaib said. "That's all right. The haters will shut up on Monday when we win."

Clinton angered Democrats when she said in an interview promoting a Hulu documentary, she would be reluctant to support 2016 nemesis Sanders should he secure the 2020 nod.

The pushback against Clinton is now in full force after she's been on the national stage for nearly 30 years. In 1992, Bill and Hillary Clinton were fresh political faces and the object of considerable fascination. As President Bill Clinton's eight years in the White House wound down, Hillary Clinton ran and won a New York Senate seat, then served as President Barack Obama's secretary of state during his first term.

She never really disappeared from the spotlight, though, within a couple of years, launching her second presidential campaign, which ended up in surprise defeat at Trump's hands.

After two losing bids, however, many prominent Democrats are wary about hearing from her anymore.

On Jan. 21, Tommy Vietor — a Pod Save America co-host and former Obama administration official who worked on the 2008 Obama campaign that dashed Clinton’s White House hopes that cycle — lashed out at her for her "inexcusable" remarks about Sanders.

"If Bernie wins the nomination, we all need to work our asses off to help him win. If someone else is the nominee, we all do the same for them. Don't kick up this bullshit right before Iowa, especially after complaining about Bernie's lack of support in 2016," Vietor tweeted .

Democratic strategist Brad Bannon blasted Clinton’s “popping off” at Sanders “as uncalled for” given “the main goal of Democrats is to beat Donald Trump.”

Bannon also slammed Clinton for prioritizing herself over “party unity,” suggesting she heed President Ronald Reagan’s “11th commandment, which was don’t speak ill of fellow Republicans.”

“It may be bad for Democrats, but it may be good for the ratings for her Hulu documentary,” he told the Washington Examiner. “There may be a part of this where there are definitely some resemblances between the Democratic race in 2016 and 2020. She may see that and may be having 2016 flashbacks.”

Bannon suspected “she still wants to be relevant,” but recommended Clinton instead make the case against Trump rather than dredge up old grievances with Sanders, who claimed the Democratic National Committee "rigged" the 2016 primary against him.

“If she keeps on this track of criticizing Bernie Sanders, she is just going to dig a deeper hole for herself,” he said.

Republican strategist Brad Todd put it less diplomatically.

“Hillary’s ego blinds her to the fact that nobody in either party wants to hear from her, and the fact that criticizing Bernie just reminds his supporters that the Democratic machine is out to get him,” he told the Washington Examiner in an email.

Clinton has been omnipresent during the 2020 campaign, fueling speculation she herself was weighing a third stab at the White House until she missed a host of filing deadlines. Polls last fall even had her and 2020 front-runner, former Vice President Joe Biden, 77, neck-and-neck for the nomination.

“Maybe there does need to be a rematch. I mean, obviously I can beat him again," Clinton said of Trump at the time .

The chatter irked liberal activists such as Michael Brooks, a Democratic analyst and left-wing radio show host, given the ascendancy of Sanders and, to a lesser extent, his ideological ally Massachusetts Sen. Elizabeth Warren, 70.

“You got like Hillary Clinton getting spicy on Twitter, saying, 'Don’t tempt me to run again.' What are you talking about? You lost,” Brooks told the Washington Examiner.

Jitters regarding the rise of Sanders have resurfaced before the Feb. 3 Iowa caucuses as he continues to match center-left Biden in the polls.

“Don’t underestimate the fact that Bernie, a lot of what he says, the messages, basically, 'You can live your life for free, we'll have free college tuition, we'll have free this, we’ll forgive your student debts,' it's a powerful message," Jim Messina, Obama's 2012 campaign manager, said in late January.

Yet, Messina added, “In the general election, it's a message that I think is going to get him killed. I think he’s the worst candidate in a general election for exactly that reason.”

Clinton has also been a foil for Tulsi Gabbard , a Sanders ally who is suing Clinton for defamation after she asserted last October that the Hawaii congresswoman and White House hopeful was “a favorite of the Russians.” Clinton also said the Kremlin believed Gabbard could be persuaded to announce a third-party bid for the Oval Office, boosting Trump’s chances of reelection as a spoiler. Gabbard enjoyed a spike in Google searches and fundraising amid the spat, helping her qualify for the November debate in Atlanta, her last appearance at the forums so far.

"It should have been for $50 billion," Gabbard said of her $50 million lawsuit . "What is your life worth to you? What is your honor and loyalty and your identity worth to you?"

Sensing she’d misstepped, Clinton walked back her initial Sanders statements.

“I thought everyone wanted my authentic, unvarnished views!” she tweeted . “But to be serious, the number one priority for our country and world is retiring Trump, and, as I always have, I will do whatever I can to support our nominee.”

The damage, however, may have already been done.