The Trump administration on Thursday shifted course in its handling of the Jamal Khashoggi case, responding to increased pressure from GOP critics and others calling on the president to hold Saudi Arabia accountable for the apparent death of the U.S.-based journalist in Turkey.

President Trump Donald John TrumpSteele Dossier sub-source was subject of FBI counterintelligence probe Pelosi slams Trump executive order on pre-existing conditions: It 'isn't worth the paper it's signed on' Trump 'no longer angry' at Romney because of Supreme Court stance MORE issued his sternest rebuke of Saudi Arabia so far on Thursday afternoon, telling reporters on the tarmac of Joint Base Andrews that “it certainly looks” as though the Washington Post columnist was murdered, and he threatened “very severe” consequences for Saudi Arabia if they’re found to be responsible.

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Earlier in the day, Treasury Secretary Steven Mnuchin Steven Terner MnuchinOn The Money: Anxious Democrats push for vote on COVID-19 aid | Pelosi, Mnuchin ready to restart talks | Weekly jobless claims increase | Senate treads close to shutdown deadline Vulnerable Democrats tell Pelosi COVID-19 compromise 'essential' Pelosi asks panels to draft new COVID-19 relief measure MORE announced his withdrawal from a high-profile investment summit in Riyadh next week, marking the administration’s first public rebuke of the Saudis over the incident. He announced his plans after discussions with Trump and Secretary of State Mike Pompeo Michael (Mike) Richard PompeoPutin nominated for Nobel Peace Prize The Hill's Morning Report - Sponsored by Facebook - Trump previews SCOTUS nominee as 'totally brilliant' Pompeo accused of stumping for Trump ahead of election MORE, who met with top Saudi and Turkish officials earlier this week.

Pompeo said Thursday that Saudi Arabia would have “a few more days” to complete an investigation into the disappearance of Khashoggi, who entered the Saudi consulate in Istanbul on Oct. 2 and hasn’t been seen since. He said he emphasized to the Saudis that the U.S. takes this matter "very seriously."

He also signaled that the administration would not sit back and wait for an open-ended investigation by Saudi officials to stretch on for weeks.

“They made clear to me that they, too, understand the serious nature of the disappearance of Mr. Khashoggi,” Pompeo said. “They also assured me that they will conduct a complete, thorough investigation of all of the facts surrounding Mr. Khashoggi, and that they will do so in a timely fashion.”

The developments reflect a recognition within the administration that its tolerant stance on Saudi Arabia — including instances of Trump repeating the denials of King Salman and Crown Prince Mohammed bin Salman of any knowledge of Khashoggi’s death — is no longer tenable.

Until Thursday, Trump and his top aides had been reluctant to criticize the Saudis over Khashoggi's disappearance and the president even floated the possibility that “rogue killers” were responsible for the alleged attack.

Several GOP lawmakers called on Mnuchin to skip the conference in Saudi Arabia while others complained about a lack of information about the investigation from the White House and State Department.

After days of silence, Senate Foreign Relations Committee Chairman Bob Corker Robert (Bob) Phillips CorkerHas Congress captured Russia policy? Tennessee primary battle turns nasty for Republicans Cheney clashes with Trump MORE (R-Tenn.) said Wednesday that it appeared the administration was trying to protect the Saudi royal family from a public relations fallout.

Corker told The Washington Post that the administration had clamped down on intelligence related to Khashoggi’s disappearance in an effort to avoid implicating senior Saudi officials.

While the president and his senior advisers responded more forcefully Thursday, they also sent mixed signals by leaving the probe in Saudi hands. Pompeo, for example, said he did not listen to the audio recordings that Turkish officials say they have of Khashoggi’s torture and interrogation in the Saudi consulate.

New reports this week from Turkey have said a team of Saudi agents intercepted Khashoggi inside the consulate, cut off his fingers, beheaded him and then dismembered his body.

Saudi rulers are considering blaming a top intelligence official close to the crown prince for the alleged murder, according to The New York Times.

That would represent a significant shift for Saudi Arabia, one that would also absolve Crown Prince Mohammed but subsequently contradict reported U.S. and Turkish intelligence showing he was connected to the operation.

The administration is facing outrage from Republican and Democratic lawmakers in Congress who have demanded a forceful response to Saudi Arabia if its government is shown to be responsible for killing Khashoggi, whose writing has been critical of both the crown prince’s stewardship of the Saudi government and the Trump administration's foreign policy.

Growing evidence of the Prince Mohammed’s connection to the 15 Saudi agents who have been implicated in Khashoggi’s apparent death has turned opinion against him on Capitol Hill.

Sen. Lindsey Graham Lindsey Olin GrahamSteele Dossier sub-source was subject of FBI counterintelligence probe Hillicon Valley: Subpoenas for Facebook, Google and Twitter on the cards | Wray rebuffs mail-in voting conspiracies | Reps. raise mass surveillance concerns Key Democrat opposes GOP Section 230 subpoena for Facebook, Twitter, Google MORE (R-S.C.), normally one of Trump’s most stalwart allies, said this week that MBS — as Mohammed bin Salman is known — “has got to go.”

“Saudi Arabia is a strategic ally, but the last thing we want to do is continue on with a ‘Business as Usual’ approach until the killing of Mr. Khashoggi is resolved,” he tweeted Thursday.

After Trump delivered his latest comments, Graham said he had spoken with the president and that his team is doing a "good job" handling the Khashoggi crisis.

Rep. Mark Meadows Mark Randall MeadowsAnxious Democrats amp up pressure for vote on COVID-19 aid Pelosi hopeful COVID-19 relief talks resume 'soon' The Hill's Morning Report - Sponsored by Facebook - GOP closes ranks to fill SCOTUS vacancy by November MORE (R-N.C.), head of the ultra-conservative Freedom Caucus and a close Trump ally, said Thursday the crisis "must be addressed in a firm and resolute manner," but he did not provide details of what actions he wants to see.

He also declined to say whether he has spoken with Trump about Khashoggi, saying his conservations with the president are private.

Republicans have indicated they would not accept a probe designed to exonerate top Saudi officials.

“America can't excuse & minimize the brutal & gruesome murder of Jamal Khashoggi, a US resident & columnist,” Mitt Romney Willard (Mitt) Mitt RomneyTrump 'no longer angry' at Romney because of Supreme Court stance GOP lawmakers distance themselves from Trump comments on transfer of power McConnell pushes back on Trump: 'There will be an orderly transition' MORE, a Republican Senate candidate in Utah and the GOP's 2012 presidential nominee, tweeted Thursday. “Our country is defined by human values, by principle above convenience, & by commitment to morality. We must subject the perpetrators of this outrage to withering sanction.”

Pompeo and Trump, who has put a strong relationship with Saudi Arabia at the center of his foreign policy, have both come under criticism for their handling of the Khashoggi crisis.

Trump on Wednesday denied that he is trying to offer cover for the Saudis a day after comparing Saudi Arabia to Supreme Court Justice Brett Kavanaugh Brett Michael KavanaughTrump faces tricky choice on Supreme Court pick The Hill's 12:30 Report: Trump stokes fears over November election outcome The Hill's Morning Report - Sponsored by Facebook - Trump previews SCOTUS nominee as 'totally brilliant' MORE, telling the Associated Press: “Here we go again with, you know, you’re guilty until proven innocent. I don’t like that.”

TV footage of Pompeo in Riyadh showed him with a smile on his face, and he also was criticized for saying he did not talk about “any of the facts” on the Khashoggi matter with Saudi officials during his visit.

There have been signs that the White House has been unhappy with media coverage suggesting they’ve taken too soft a line with Saudi Arabia, and that both Pompeo and Trump would like to correct that impression.

Trump in a tweet Thursday said he had discussed the Khashoggi case “in great detail” with Pompeo and that “he is waiting for the results of the investigations being done by the Saudis and Turkey.”

Vice President Pence offered some of his most pointed comments yet on the case, telling reporters in Colorado on Thursday that “if a journalist lost their life at the hand of violence, that is a threat to a free and independent press around the world and there will be consequences.”

“I can assure you that we’re going to follow the facts,” he added.

Turkish police have expanded their investigation into Khashoggi's disappearance, saying they will search two areas outside Istanbul in addition to a second search of the Saudi consulate.

Even as Trump and Pompeo sought to signal they were taking a serious approach to the matter and needed to hear explanations from Riyadh, Pompeo also talked about how the administration wants to maintain its alliance with Saudi Arabia.

“I think it's important for all of us to understand, too, we have a long — since 1932 — a long strategic relationship with the Kingdom of Saudi Arabia,” he said. “They are an important strategic alliance of the United States and we need to be mindful of that as well.”

Those comments echoed Trump's belief that any potential U.S. response must take into consideration the country's security ties to the Saudis.

The president has previously said he does not want to cancel or suspend an agreement to sell billions of dollars worth of weapons to Saudi Arabia, arguing it would hurt American jobs.

"I don’t like the concept of stopping an investment of $110 billion into the United States,” Trump said last week. “Because you know what they’re going to do? They’re going to take that money and spend it in Russia or China, or someplace else."

Critics say Trump's response is another example of the president putting geopolitical and economic concerns ahead of human rights. They have also raised questions about whether Trump's personal financial ties to Saudi Arabia have affected his handling of the crisis.

A Saudi billionaire, Prince Alwaleed bin Talal, purchased Trump's yacht and a large stake in the Plaza Hotel in the 1990s when the former business mogul was in dire financial straits. The Saudi government bought an entire floor of the Trump World Tower in New York in 2001 and has spent hundreds of thousands of dollars at the Trump International Hotel in Washington, D.C.

Trump has denied having any financial conflicts of interest with Saudi Arabia.

Scott Wong contributed.