The Post takes a look at the highs and lows of Eli Manning’s career following Tuesday’s announcement that rookie Daniel Jones will be taking over as the Giants starting quarterback.

Highs

April 24, 2004: Amid threats he would sit out if they selected him, the Chargers draft Eli Manning with the No. 1 pick and trade him to the Giants in exchange for the fourth pick, Philip Rivers, a 2004 third-round pick, a 2005 first-round pick and a 2005 fifth-round pick.

Nov. 22, 2004: The Manning era officially begins in Atlanta, a 14-10 loss to the Falcons in which he completes 17-of-37 passes for 162 yards, a touchdown and two interceptions. It’s the first of a franchise-record 210 consecutive starts and 232 out of a possible 233.

Oct. 23, 2005: Six games into his first full year as a starter, Manning has a signature moment, a dramatic victory over the Broncos in which he finds a leaping Amani Toomer for the game-winning score with 5 seconds left.

Sept. 17, 2006: Manning rallies the Giants from a 17-point, fourth-quarter deficit against the Eagles, throwing for 371 yards and three touchdowns, including the game-winning score, a 31-yard strike to Plaxico Burress.

Feb. 3, 2008: Manning and the 12-point underdog Giants stun the 18-0 Patriots, rallying for the game-winning score with 35 seconds left in Super Bowl XLII. Manning makes the play of the game — and one of the greatest plays in Super Bowl history — by wiggling out of a heavy rush and hitting David Tyree, who pins the ball to his helmet before bringing it in for a 33-yard gain. Manning then wins it with a 13-yard TD pass to Burress en route to MVP honors.

Feb. 5, 2012: Again, Manning gets the better of the Patriots, only this time the game-winning drive comes with 57 seconds left to cap another MVP performance. Again, there is a memorable play, a 38-yard pass from Manning to Mario Manningham along the sideline.

Oct. 27, 2013: Phil Simms’ record as the Giants’ all-time passing yardage leader falls in a 15-7 win over the Eagles. With his second completion, Manning passes Simms’ mark of 33,462 yards.

Feb. 4, 2017: Manning is named the co-winner, along with Larry Fitzgerald, of the Walter Payton Man of the Year award. The award recognizes excellence on and off the field.

Lows

see also Thank you, Eli Manning Thanks, Eli. And I know I am speaking for all... : His first playoff appearance is a disaster, a three-interception nightmare as the Giants are blanked by the Panthers, 23-0. Manning throws for just 113 yards.

Nov. 25, 2007: In one of the worst performances of his career, Manning is picked off four times in an ugly 41-17 loss to the Vikings, and three of the interceptions are returned for touchdowns.

Jan. 8, 2016: Manning’s most recent playoff appearance is a forgettable one, a 38-13 loss to the Packers. He doesn’t necessarily perform poorly, throwing for 299 yards, a touchdown and an interception, but it isn’t nearly enough.

Dec. 3, 2017: With the Giants mired at 2-9, coach Ben McAdoo benches Manning and replaces him with Geno Smith. McAdoo had given Manning the option to continue his streak, but the quarterback had declined. McAdoo is fired the next day, and Manning returns as the starter.

Sept. 17, 2019: The Manning era appears to end for good, with coach Pat Shurmur announcing the team is going with rookie quarterback Daniel Jones after an 0-2 start in which the Giants suffer lopsided losses to the Cowboys and Bills.