A waiter or someone who handles food on the Ruby Princess was the likely source of a deadly outbreak of coronavirus in Australia, NSW Police has revealed.

Key points: Eighteen deaths and hundreds of confirmed COVID-19 cases have been traced back to the Ruby Princess

Eighteen deaths and hundreds of confirmed COVID-19 cases have been traced back to the Ruby Princess NSW Police said there have been offers to repatriate certain crew members on board the ship

NSW Police said there have been offers to repatriate certain crew members on board the ship Medical assistance is still be given to the 1,000 staff on board the cruise ship

Detectives have begun interviewing thousands of witnesses about what they knew about potential COVID-19 cases on board the cruise ship before it docked in Sydney more than three weeks ago.

Since disembarking, 18 passengers from the ship have died and hundreds of more confirmed cases have been linked to the vessel.

NSW Police Commissioner Mick Fuller said early indications suggested an infected crew member was most likely responsible for the outbreak.

"That would seem to be the most obvious point of transmission — someone that is handling food on behalf of multiple hundreds of people," he said.

The Commissioner is expected to give a timeframe for the investigation this morning after meeting with Premier Gladys Berejiklian.

"I would like to thank those 220 people who reached out through Crime Stoppers offering information … that could take two months alone chasing up those leads," he said.

"If you are a passenger or crew member or you have any information that may assist with the police investigation, please call Crime Stoppers."

There are still more than 1,000 crew members from more than 50 different countries on board the Ruby Princess, which docked in Port Kembla last week.

Medical teams boarded the ship on Thursday to test about 88 crew members who reported flu-like symptoms— 66 of them returned positive results.

The International Transport Workers Federation has called for all 1,000 remaining staff members to be tested, but Commissioner Fuller said Carnival had advised some of the crew wished to remain on board.

"We have made offers through Carnival Cruises in terms of repatriation of certain groups and a number of them are actually happy to stay on," Commissioner Fuller said.

"We appear to be getting get mixed messages on social media though.

"We are making every effort to get people home and we are working with Carnival to do that."

The Ruby Princess cruise arrived in Port Kembla at Wollongong last week for medical assistance. ( ABC News: Jesse Dorsett )

By Wednesday, the crew on board will have been in isolation for 10 days, but it's unclear what will happen to the ship in the near future.

"We are not going to run the ship out of port if there's multiple sick people who require a high degree of medical assistance — we won't do that," Commissioner Fuller said.

"Some may need to come off because of safety reasons.

"The balance has been with all of these cruise ships is ensuring we look after people who need to be looked after, but at the same time not overwhelm our health system."

Six thousand Australians have returned from overseas and landed at Sydney International Airport over the past two weeks and 2,700 are now in mandatory 14 days isolation in city hotels.