Priscilla Chan was selected as the recipient of the 2017 Visionary of the Year award on Thursday night in California.

The wife of Facebook founder Mark Zuckerberg, who announced earlier this month that she was pregnant with the couple's second child, was glowing as she took the stage on Thursday to accept the honor from the San Francisco Chronicle.

'I feel so grateful to have the opportunity to give back,' Chan told the audience at the event.

'I will spend the rest of my career trying to make San Francisco and the world a little bit better.'

The prestigious prize comes amidst rumors of a possible presidential run for Chan's husband, who was spotted on Thursday gleefully filming Chan with his phone as she collected her award and a $25,000 grant.

Chan later said she would be donating the grant to charity.

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Awarded: Priscilla Chan was awarded the 2017 Visionary of the Year award on Thursday night in San Francisco (above accepting her honor)

Immigrants, they get the job done: The 32-year-old daughter of Chinese immigrants who came to the US from Vietnam was honored for her philanthropic work (Chan above with Mark Zuckerberg)

Working the room: Chan's honor comes amidst mounting rumors of a possible run for president by Zuckerberg (left filming his wife, right talking to a fellow attendee)

Chan, who is the Harvard-educated daughter of Chinese refugees who came to the United States and from Vietnam, was chosen for the honor because of her philanthropic work, specifically in the fields of education and medical research.

Chan and her husband have donated $120million to San Francisco public schools and she is the chief executive officer of the Primary School, an experiment in bringing together health care and education which the couple funded almost entirely on their own.

The two also donated $75million to San Francisco General Hospital, where Chan still works in the pediatrics department and is currently the only employee with her name on a building.

And while those massive gifts have helped to make a huge impact, they pale in comparison to the $45billion that the duo is putting into the Chan Zuckerberg Initiative.

The couple announced the formation of their initiative in late 2015, stating that their goal was to 'advance human potential and promote equality in areas such as health, education, scientific research and energy.'

Then last September, they announced the creation of Chan Zuckerberg Science and their goal to cure, manage, or prevent all disease by the year 2100.

The two initially worded that goal by stating they wanted to end disease during the life of their 15-month-old daughter

They have pledged $3billion to the cause over the next 10 years and 99% of their Facebook shares over the course of their lifetime.

Chan kept things casual for the ceremony on Thursday, with the expectant mother wearing simple black dress and metallic cardigan with black flates.

Rousing words: 'I will spend the rest of my career trying to make San Francisco and the world a little bit better,' said Chan while collecting her prize and a $25,000 check

Rallying the troops: She and husband Mark Zuckerberg have donated $120million to San Francisco public schools and $75million to San Francisco General Hospital (Chan above on Wednesday speaking at a Teach for America event)

Her husband meanwhile opted for a suit instead of his standard basic t-shirt or hoodie, which will likely go out the door if he does run for president.

The rumors of a run started late last year after a few comments made by Zuckerbeg about religion and his desire to visit all of America set off alarm bells in some, especially in the wake of another billionaire outsider winning the election.

When asked if he was an atheist in December, something many thought to be true, Zuckerberg said: 'No. I was raised Jewish and then I went through a period where I questioned things, but now I believe religion is very important.'

No atheist has ever successfully run for president of the United States.

He would set himself apart however by having the most accomplished woman to ever hold the office of first lady by his side.

In collecting her prize on Thursday, Chan beat out five other very worthy nominees for the honor.

Eric Weaver, founder and CEO of the nonprofit micro-loan program Opportunity Fund; Sarah Krevans, CEO of Sutter Health; Raj Jayadev, co-founder of Silicon Valley De-Bug; Angela Blackwell, founder and president of PolicyLink; and Kimberly Bryant, founder of Black Girls Code.