Forensic experts believe genealogy websites — like the one used to catch the East Area Rapist suspect — could now hold the key to catching the Zodiac Killer.

“It is possible,” explained Pam Hofsass, a former San Francisco homicide detective who worked the Zodiac case and now runs the forensic lab for the Contra Costa County Sheriff’s Office.

“It’s totally worth looking at, and I hope with all of the news and revelations about the Golden State Killer that it will kind of be the impetus for the Zodiac,” she told The Sacramento Bee.

Speaking to the newspaper this week, experts described how a clean DNA sample — possibly taken from saliva left on envelopes that the Zodiac mailed during his reign of terror — could be the smoking gun that authorities need to finally crack the case.

They pointed out how the technology and techniques used to re-process DNA samples have improved over the years and police are now much more open to using commercial genealogy sites, such as GEDmatch, to catch culprits.

Investigators handling the Golden State Killer case used the Florida-based company to track down suspect Joseph James DeAngelo, who had been hiding in plain sight for decades as a former cop. They were finally able to catch him last week after taking a crime-scene DNA sample and running it through the GEDmatch database to see if he had any relatives.

While more than 100 users came up as a match, authorities were eventually able to narrow down their search to just DeAngelo and later confirmed — through further testing — that he was a genetic match.

Forensic experts hope investigators will now take a second look at the mixed DNA samples found in the Zodiac case, specifically the ones that had been pulled from the envelopes and stamps mailed by the suspected killer.

“I think they are worth re-examing,” Hofsass said. “That would go for all of the (law enforcement) agencies that received mail (and) taunting cards.”

Tom Voight — recreational Zodiac expert and founder of the website zodiackiller.com — agreed — saying he, too, felt like the mail was worth a second look.

“I think Zodiac was definitely licking his own stamps and envelopes,” Voight told the Bee. “You just need to get the evidence, get it to the lab. Just copy what was done with the Golden State Killer.”

Between 1968 and 1969, the Zodiac terrorized Northern California — committing at least five murders and sending numerous cards and letters to newspapers and police, which contained secret codes and cyphers.

Experts have tried running a partial DNA sample found from the surface of a Zodiac letter stamp through the federal criminal database, and even compared it to three rumored suspects, the Bee reports. But they’ve been unable to find a match.

Voight and others hope the law enforcement agencies in charge of the Zodiac case — which is “pending inactive,” but still technically open — will come together and see if they can find someone who matches online.

“If California law enforcement authorities would simply join forces as they did with the Golden State Killer … then this would be a pretty big year because I don’t think it would take very long to catch him,” Voight said.

“I would expect to see a renewed interest in forming some kind of collaborative effort,” Hofsass added.