Michael Che, the other co-anchor of “Weekend Update,” noted that the Weinstein scandal put comedians in a “tough spot” because it was hard to make jokes about sexual assault. Then, with a photo of Mr. Weinstein on the screen, Mr. Che added:

“But it’s so easy to make jokes about a guy that looks like this. I mean, he looks like chewed bubble gum rolled in cat hair.”

Mr. Che also took issue with Mr. Weinstein saying that everyone makes mistakes.

“You assaulted dozens of women. That’s not a mistake — that’s a full season of ‘Law & Order.’ Your name’s a verb now, dude, as in, ‘If this guy tries to Weinstein me, I’m going to cut off his little Harvey.’ Doesn’t he look like a well-dressed skin tag?”

An earlier sketch that riffed on the Weinstein scandal seemed to play more awkwardly. Set at a panel during the New York Film Festival, the segment featured the “S.N.L.” cast members Leslie Jones (as Viola Davis), Cecily Strong (as Marion Cotillard) and Kate McKinnon (as Debette Goldry, a fictional — and often disoriented — actress from Hollywood’s past) discussing the topic of sexual harassment.

Asked if her character had faced harassment in her time, Ms. McKinnon answered:

“Good Friday, where do you want me to start? Women being harassed is Hollywood, all right? Everything old is new again. Producers are abusing starlets, there’s Nazis marching in the street, suddenly nude pantyhose are on trend. I’ve never felt more at home. When’s polio coming back? This’ll be fun.”

Speaking specifically of Mr. Weinstein, Ms. McKinnon’s character said that she once took a meeting with him.