The world of movies and the world of comedy has lost a legend as actor and comedian Harold Ramis has died at the age of 69. The actor had been suffering from a number of health issues in recent years and finally succumbed to his battle with them on Monday.

Per the Chicago Tribune:

Ramis, a longtime North Shore resident, was surrounded by family when he died at 12:53 a.m. from complications of autoimmune inflammatory vasculitis, a rare disease that involves swelling of the blood vessels, his wife Erica Mann Ramis said. He was 69.

Ramis is perhaps best known for his work in 80s comedies with his collaborators Bill Murray and Dan Aykroyd. The trio helped create some of the classic comedies we revere today such as Ghostbusters, Caddyshack and Stripes. He also has writing credits on such classics as Animal House, Meatballs and Groundhog Day.

In addition to his acting and writing talents, Ramis branched out into directing as well, crafting classics like National Lampoon’s Vacation as well as the criminally underrated Analyze This, among many others. His films weren’t always lauded by critics but they definitely found a niche and they certainly helped inspire some of the comedic filmmakers we have working in Hollywood today.

Ramis may not be with us anymore, but the work he leaves behind speaks for itself and he’ll live on in those that he inspired while he was here.