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The district attorney’s office has continued the investigation, but no charges have been announced and nothing has been said publicly about its scope or timetable.

Prosecutors are also investigating at least one other allegation, first reported in The New Yorker, that Mr. Weinstein forced a student actress, Lucia Evans, to perform oral sex on him during a business meeting at his office in 2004, two people familiar with the investigation said.

Prosecutors have also expanded the inquiry to include possible financial crimes involving Mr. Weinstein’s former production company, subpoenaing a wide range of records. The team looking at Mr. Weinstein also includes prosecutors from the Major Economic Crimes Bureau, according to two people familiar with the subpoenas.

Mr. Weinstein’s lawyer, Benjamin Brafman, said the sexual encounters the district attorney’s office has been scrutinizing were consensual. “The substantial delay in this investigation has been the result of serious flaws that are apparent with respect to any claim of non-consensual sex,” he said. He also denied Mr. Weinstein had committed any financial wrongdoing, asserting that he had reimbursed his former company for all personal expenditures.

Now the Manhattan district attorney, Cyrus R. Vance Jr., has turned to Ms. Illuzzi, one of the most successful prosecutors in his office. A veteran homicide prosecutor, she was on the team that won a conviction against Pedro Hernandez for the killing of 6-year-old Etan Patz. In 2016, she ran as the Republican candidate for district attorney on Staten Island, where she lives; she lost to the Democratic candidate, Michael McMahon.