Cain Velasquez (L) will attempt to gain revenge on Fabricio Werdum (R) when they rematch at UFC 207 in Las Vegas on Dec. 30. (Getty Images)

Cain Velasquez will get a chance to avenge perhaps his most disappointing loss when he rematches with Fabricio Werdum on the main card at UFC 207 on Dec. 30 at T-Mobile Arena in Las Vegas in a battle of former heavyweight champions. That card will be headlined by a women’s bantamweight title fight between champion Amanda Nunes and former champion Ronda Rousey.

Werdum stunned Velasquez at UFC 188 in Mexico City on June 12, 2015, when he submitted him in the second round to win the heavyweight title. Werdum then lost the title in his first defense, against Stipe Miocic. He defeated Travis Browne last month at UFC 203 in Cleveland.

Velasquez, who has battled a string on injuries in his career, stopped Browne in the first round at UFC 200 in Las Vegas in his first bout since losing the belt to Werdum.

Velasquez has been known as “Cardio Cain” throughout his career for his great conditioning, but he underestimated the impact that Mexico City’s altitude would have on his body when he fought Werdum at UFC 188. Werdum spent his entire training camp in the mountains in Mexico and was much fresher than Velasquez as the bout wore on.

It was obvious late in the first round that Velasquez was having difficulty catching his breath and he was unable to get a second wind.

The winner of the bout is expected to be the No. 1 contender for a heavyweight title fight with Miocic.