The specific metabolic processes that are ultimately responsible for causing all of this damage are still only partially understood. The good news is that we don’t need to answer the many open questions about the causes of structural decay in order to develop effective therapies to reverse it. No matter what caused a given unit of damage in the first place, the same regenerative therapeutics can be used to repair it. In other words, it doesn’t matter how a given microscopic lesion occurred, if we apply rejuvenation biotechnologies that restore the machinery of life to proper working order.

The even better news is that we now understand how to fix all of this damage. For each major class of aging damage, a strategy for its removal or repair either already exists in prototype form, or is foreseeable from existing scientific developments: see the specific “Rejuvenation Biotechnology” listed for each kind of aging damage in the Table, and click the program name to learn more.

Even after we have used these new therapies to repair an aging tissue, metabolic processes will continue to cause new damage. This simply means that rejuvenation biotechnologies are not a one-off fix, but will need to be periodically repeated to preserve youthful function. Just as cars need regular rounds of oil changes and spark plug replacements to keep them running smoothly, people will need to go in to rejuvenation clinics to keep up with their regenerative treatments to continue postponing age-related disease.

The entire SENS strategy – from the kinds of aging damage that occur, to their contribution to age-related frailty and illness, to the rejuvenation biotechnologies that can repair and replace the damaged functional units – are described in detail in Ending Aging, by SENS Research Foundation Chief Science Officer Dr Aubrey de Grey and Science Writer Michael Rae. Copies are available from your local bookstore, or from Amazon.com and other online retailers.

Through groundbreaking research in rejuvenation biotechnology, SENS Research Foundation is catalyzing the development of new medical therapies to comprehensively address the disabilities and diseases of aging, leading to a reimagined aging. Please help advance and expand our critical scientific research.