WASHINGTON—Federal officials are considering seeking a preliminary injunction against Facebook Inc. over antitrust concerns related to how its products interact, according to people familiar with the matter.

If it materializes, the action by the Federal Trade Commission would focus on Facebook’s policies concerning it how it integrates its apps or allows them to work with potential rivals, these people said. Alongside its core social network, Facebook’s key products also include Instagram, Messenger and WhatsApp.

The...