Lorena Blas

USA TODAY

American Horror Story and Glee creator Ryan Murphy is getting ready for Pose, his potential new FX series set in the 1980s.

And in the process, the production is making history: Murphy's team has assembled what it calls the largest cast of transgender actors in regular roles for a scripted series.

The pilot episode, expected to begin filming in November, will look at various cultural angles in New York, including the affluent Trump-era elite, the downtown social and literary scene and the LGBT ball culture. Murphy co-created the show with frequent collaborator Brad Falchuk and Steven Canals.

Among transgender cast members portraying authentic transgender characters: MJ Rodriguez (Nurse Jackie, The Carrie Diaries, Luke Cage); Indya Moore (Saturday Church); fashion model and New York ball-scene icon Dominique Jackson; Hailie Sahar (Mr. Robot, Transparent); and Angelica Ross (Transparent, Claws).

Additionally, Tony Award winner Billy Porter (Kinky Boots), Ryan Jamaal Swain and Dyllon Burnside also have been cast.

Other cast members were announced Thursday: Evan Peters (American Horror Story, the X-Men franchise), Kate Mara (American Horror Story, House of Cards), James Van Der Beek (Varsity Blues, Dawson’s Creek, What Would Diplo Do?) and Tatiana Maslany.

Acclaimed choreographer Ryan Heffington (Sia’s Chandelier video, The OA) will choreograph scenes featuring Maslany’s dance teacher and Swain's student characters.

Trans activist director Silas Howard will be a co-executive producer of the series, which will also mentor emerging transgender directors, FX says.