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Green Bay --- Aaron Rodgers and the Packers offense would prefer Sunday to become a game of match-ups. If Green Bay's no-huddle is humming and the San Francisco 49ers defense is stuck in one personnel grouping, Rodgers could have some opportunities in the passing game.

Especially considering this a hurting 49ers' secondary.

Both cornerback Carlos Rogers and Eric Wright are listed as questionable with hamstring injuries. After not practicing all week, Rogers may be a long shot. He injured his hamstring last weekend against Arizona and didn't sound optimistic on Friday.

"I ran on it but I don't know," Rogers told Cam Inman of the San Jose Mercury News.

Rogers has been a key piece of the 49ers' defense. This season, the 32-year-old had 47 tackles, two interceptions and eight pass break-ups. Against Green Bay in Week 1, Rogers often covered Randall Cobb in the slot. And the veteran Wright figured to supplant Rogers at that spot, but joined the injury list himself midweek with a hamstring injury.

Further complicating things for San Francisco may be the imminent cold weather, not ideal conditions for a hamstring pain. If neither corner can go, the 49ers may turn to Perrish Cox.

In the opener, Rodgers completed 21 of 37 passes for 331 yards and three touchdowns.

The Packers don't believe the cold will slow their no-huddle offense. On Sunday, the 49ers may need to decide drive to drive when to use an extra defensive back to contain Green Bay's receivers and when to creep a defender into the box to stop Eddie Lacy. It appears they'll be making these decisions with two key players battling injuries.

San Francisco has Tarell Brown and Tramaine Brock at corner, then questions.

"On the back end," Rodgers said this week, "you've got a young player like (safety) Eric Reid, who has had a very good season. (Donte) Whitner, he’s a very good player. Tarrell Brown is one of the more underrated corners in the league. I think he does a great job in man coverage. They ask him to do a lot. Brock has stepped in and done a really nice job and Carlos Rogers is… a compliment here, he reminds me of Charles Woodson in the slot, a tough position to play and he plays at a high level. So, it’s a talented defense and it’s hard to pick out one guy.

"There’s not a recipe I think to get after them. You have to be very accurate throwing the football and you have to execute your offense as well as you can."