Given the current outbreak, unprecedented in terms of number of people killed and rapid geographic spread, Science and Science Translational Medicine have made this collection of research and news articles on the viral disease freely available to researchers and the general public.

Science reporters have highlighted these top stories from their coverage as must reads:

Research

26 March 2015 | Research Report Mutation rate and genotype variation of Ebola virus from Mali case sequences Ebola virus has not mutated faster during the current outbreak in West Africa than historically observed..

26 March 2015 | Research Report An Ebola whole-virus vaccine is protective in nonhuman primates Preliminary results in primates offer promising results for an inactivated, peroxide-treated whole virus vaccine candidate for Ebola.

20 November 2014 | Science Careers Profiles The road to Ebola A structural biologist, a molecular virologist, and a microbiologist share their stories on why they considered working with Ebola.

30 October 2014 | Research Report Strategies for containing Ebola in West Africa A combination of hygienic practices could feasibly check Ebola within six months.

30 October 2014 | Research Report Host genetic diversity enables Ebola hemorrhagic fever pathogenesis and resistance Intercrossed mice infected with Ebola virus show the spectrum of pathology from prolonged coagulation to total resistance.

20 August 2014 | Research Article Marburg virus infection in nonhuman primates: Therapeutic treatment by lipid-encapsulated siRNA Lipid nanoparticle delivery of siRNAs against the virus nucleoprotein treats Marburg virus infection in nonhuman primates after symptom onset.

19 August 2014 | Editors' Choice How Ebola Shuts Down Antiviral Signaling

16 October 2013 | Research Article Monoclonal antibodies and interferon therapy rescue Ebola-infected nonhuman primates when administered after symptoms start Monoclonal antibodies and adenovirus-vectored IFNα extends the treatment window for Zaire ebolavirus in macaques.

21 August 2013 | Research Article Therapy for Ebola virus infection in rhesus macaques with a monoclonal antibody cocktail Ebola virus-infected macaques were successfully treated with a cocktail of monoclonals manufactured in plants.

19 June 2013 | Research Article Estrogen receptor modulators inhibit Ebola virus infection Clomiphene and toremifene inhibit Ebola virus infection.

31 October 2012 | Research Article Immune parameters correlate with protection against Ebola virus infection Antibody induction may serve as a surrogate for survival in protecting against Ebola infection.

13 June 2012 | Research Article Successful treatment of Ebola virus–infected macaques with monoclonal antibodies Macaques survived infection with Ebola virus when treated 24 hours after infection with mix of 3 neutralizing monoclonal antibodies. C. Bickel/Science

29 February 2012 | Research Article Productive Replication of Ebola Virus Is Regulated by the c-Abl1 Tyrosine Kinase Productive replication of Ebola virus is modulated by the c-Abl1 tyrosine kinase.

2012 | Perspective Emerging Disease or Diagnosis? Some viral infections, including ebolavirus, may not represent emerging diseases, but improved detection and diagnosis of common diseases.

2009 | Report Discovery of Swine as a Host for the Reston ebolavir Respiratory infections in pigs in the Philippines are associated with a cocktail of viruses, including a monkey filovirus.

2006 | Report Ebola Outbreak Killed 5000 Gorillas Successive waves of Ebola virus infection and hunting pressure are threatening the great apes of West Africa with extinction.

2005 | Brevia Endosomal Proteolysis of the Ebola Virus Glycoprotein Is Necessary for Infection For the Ebola virus to infect successfully, a host enzyme must digest a surface protein on the virus, suggesting a new target for treatment of this fatal infection.

Related

3D model of the Ebola virus

Ivan Konstantinov et al.Visual Science

Honorable mention in the 2011 International Science and Engineering Visualization Challenge