A trust that has donated millions to medical science, healthcare, education and the arts in the UK has announced it is suspending all new giving as it faces legal cases amid the opioid drug crisis in the US.

The Sackler Trust is run by the Sackler family, members of which own Purdue Pharma, a company selling the prescription painkiller OxyContin.

The business is facing hundreds of lawsuits in the US aiming to hold it to account for its alleged role in the country's opioid drug crisis.

Earlier this month, a £1 million donation to the National Portrait Gallery was cancelled, and the trust has now said all philanthropic giving will temporarily cease so the issue "will not be a distraction for institutions that are applying for grants".

Commitments that have already been made will be honoured.

Sackler Trust chairwoman Dame Theresa Sackler said in a statement issued on behalf of the trustees: "I am deeply saddened by the addiction crisis in America and support the actions Purdue Pharma is taking to help tackle the situation, whilst still rejecting the false allegations made against the company and several members of the Sackler family.

"The current press attention that these legal cases in the United States is generating has created immense pressure on the scientific, medical, educational and arts institutions here in the UK, large and small, that I am so proud to support.