I tried the Destroy ending first, because that was the only ending where Shepard lived. Didn't really like the rest of the outcome so I tried the others, during which I realized Destroy was the Renegade ending while Control was the Paragon ending, and I had been trying to go for a Paragon game. Synthesis I think is the "Ultimate" ending, considering what it does, and is the ending I prefer, and hope that Bioware goes with that ending as Canon for ME Andromeda.