A wave of gun thefts across New South Wales has sparked calls for a crackdown on weapons in homes.

At least 50 guns and thousands of rounds of ammunition have been stolen from registered gun owners across the state in just over a fortnight.

In at least three cases in the past month, entire gun safes have been taken.

On Tuesday night, bandits broke into a house at Tumut, in the state's south, and removed a safe containing four rifles while a man and woman were asleep in their beds.

The same day, robbers stole 16 registered pistols and rifles from a property at Kenebri, in north-western NSW.

Police are investigating whether the same criminals stole two safes containing a total of 19 guns from a property and a shipping container at nearby Coonabarabran.

Detectives have no doubt some of the gun owners have been targeted and are investigating how the robbers tracked them down.

All firearms used by permit holders in the state must be registered with the Commissioner of Police, but police insist the information is secure.

The Commander of the Firearms and Organised Crime Squad, Ken Finch, says there is no evidence the registry has been compromised.

"I'm quite confident that the processes and systems that are in place at the firearms registry are robust and their audit systems are transparent," he said.

Detective Superintendent Finch says in many cases, the robbers knew what they were looking for.

"Very often in rural areas, the local population know who own guns within communities and very often, people who have multiple firearms are in fact members of gun clubs," he said.

"So the fact is, information about who actually possesses firearms in communities can come from a variety of sources."

Greens MP David Shoebridge is calling for urgent laws to cap the number of weapons people can own.

"We propose a limitation of three, similar to that in WA, but the NSW Police Minister is captured by the Shooters Party and is refusing to act," he said.

"While there are private arsenals around NSW, criminals will target that.

"The average number of guns per licence owner is now five. That's a honey pot that criminals are targeting."

Det Supt Finch says police would welcome any moves to restrict the number of guns accessible to the public.

The State Government is not planning to limit gun ownership any further but it is considering tightening the rules on weapons storage.

A spokesman for NSW Police Minister Mike Gallacher says he is also holding talks with the Federal Government and counterparts across the country to develop a uniform response to gun crime.

Opposition leader John Robertson says while the discussions roll on, the thefts are continuing to fuel Sydney's wave of shootings.

"While we continue to see illegal firearms on the streets and our police numbers down, people in western and south-western Sydney are being failed by this Government," he said.

Earlier this week, police announced they had seized and destroyed nearly 1,500 guns from criminals in the past two months.

But they concede gun theft has been a growing problem for at least a decade.