Jim Gaffigan's comedy covers a wide range of domestic issues, including the fact that he and his wife, Jeannie, actually have five children under age 9 in a two-bedroom New York apartment.

"You know what it's like having five kids?" he asks his audience. "Imagine you're drowning. And someone hands you a baby." He says his favorite ride at Disney World during a recent family visit was "the air-conditioned bus back to the airport." Sometimes he talks about how pale his complexion is: Picture a...