After dropping the first game of the series, No. 6 Alabama responded harshly.

A 16-2 win over Missouri on Monday was the second straight run-rule win over the Tigers to take the series. Following the 7-3 Game 1 loss, the Crimson Tide outscored the visitors 25-3. The 16 runs scored in Game 3 was the most for Alabama since recording 19 against South Carolina in 2012.

Alabama (29-6, 3-3 SEC) did it with a 12-run second inning to start the rout. The outburst included a two-run single from Kallie Case and three-run homers from both Marisa Runyon and Reagan Dykes. Runyon, who had two home runs in Game 2 on Saturday, had four RBIs in Monday's win.

Four Alabama batters had at least two hits. Haylie McCleney went 2-for-3 with three runs scored. Chandler Dare, Runyon and Case also scored three times apiece.

No. 16 Missouri (24-6, 3-3) had three errors while recording just four hits.

Sydney Littlejohn (12-2) pitched all five innings, throwing 70 pitches with both runs earned.

Up next for Alabama is No. 1 Florida. The Tide travels to face the Gators (33-1, 8-1) starting at 5 p.m. CT Friday in Gainesville.