Version 3 Version 3 05.02.20, 03:33 Version 2 04.02.20, 08:38 Version 1 24.01.20, 09:25 preprint preprint Preprints are manuscripts made publicly available before they have been submitted for formal peer review and publication. They might contain new research findings or data. Preprints can be a draft or final version of an author's research but must not have been accepted for publication at the time of submission. revised on 05.02.2020 and posted on 05.02.2020 Martin Stoermer by

A regional outbreak of pneumonia in Wuhan, Hubei Province of China in late 2019 was associated with a novel coronavirus. Rapid release of genomic data for the isolated virus enabled the construction of first-generation homology models of the new CoV 3CLpro cysteine protease. Whilst the overall viral genome was most closely associated with bat coronaviruses, the main protease is most closely related (96% identity) to SARS CoV protease.

History

Email Address of Submitting Author martin.stoermer@uq.edu.au Institution The University of Queensland Country Australia ORCID For Submitting Author 0000-0003-3445-2104 Declaration of Conflict of Interest I declare that there are no conflicts of interest. This work is entirely derived from data in the public domain Version Notes 17/01/2020 Initial ChemRxiv upload - awaiting feedback from data suppliers 20/01/2020 Submission 5/2/2019 - Revised title