For nearly 15 years, Eli Manning walked off fields as a winner or a loser and felt the appropriate emotions commensurate with each result. On Nov. 1, 2015, Manning came off the turf inside the Superdome in his hometown of New Orleans feeling a bit different than ever before.

“It was a wild one,’’ Manning said this week. “Just back and forth and high scoring. Had an opportunity to win at the end and had a crazy kickoff return and field goal. I don’t know if I’ve ever been in anything quite like that one.’’

No, Manning was never involved in a game quite like that one. He threw a career-high six touchdown passes, but Drew Brees threw for seven and the Saints beat the Giants, 52-49. With Manning set to face the Saints on Sunday at MetLife Stadium, it is impossible not to recall that shootout.

“It was weird,’’ Manning recalled. “You felt you did a lot of stuff, we also had a chance to win it at the end with a two-minute drive and we had to punt. Obviously you could always do more. Yeah, felt like you play a great game and lose. A lot of teams have probably felt that a little bit against the Saints. They got the ability to score a lot of points.’’

Each week, Odell Beckham Jr. goes against the top cornerback on the opposing team. This week, it is Marshon Lattimore, the NFL’s 2017 defensive rookie of the year.

“I presented him the award, so I know that he’s very, very good,’’ Beckham said. “Even watching film, he’s just different. I don’t know the word — not sturdy, but he’s just very balanced, and he’s very good.’’

Beckham said he is not sure if Lattimore will follow him all over the field.

“I don’t know exactly if it’s going to be a match up, if he’s following you here, there, this that and the other, but we have a challenge ahead of us,’’ Beckham said.

Manning, 37, for several seasons has usually been the older of the two quarterbacks when he steps on the field but not this time, against Brees, 39. The last time Manning played in a game with an older starting quarterback? Nov. 27, 2016, when Josh McCown started for the Browns in a Giants victory in Cleveland. Prior to that, it was when Brees and the Saints visited on Sept. 18 of that year.

Saquon Barkley’s 216 rushing yards is the most prolific three-game start for a Giants running back in 71 years and the third-highest three-game start in franchise history. Hall of Famer Tuffy Leemans had 238 yards after three games in 1936 and Hank Soar had 217 yards in 1937. … Coach Pat Shurmur described LT Nate Solder as “a steady performer. Good, great, good — he plays well and plays pretty steady all the time.’’ Solder last week had his best game this season, stoning Houston’s Jadeveon Clowney.

Losing TE Evan Engram — out 3-4 weeks with a sprained knee — means others will have to pick up the slack in the passing game.

“I think it puts more stress on all of us,’’ Beckham said. “We’ve got to pick up for him, unfortunately. I wish that he was playing.’’