Denver jurors could begin hearing arguments as early as today in the drunken driving homicide case against 27-year-old Victoria Barry.

Authorities allege Barry, mind clouded by alcohol, drove the wrong way on Interstate 25 just before midnight May 14, 2011, smashing into and killing Lilly Duncan, a single parent on her way back from Colorado Springs.

The accident occured on northbound I-25 near Downing Street.

Barry faces a felony charge of vehicular homicide involving DUI among other charges in a Denver District Court trial that opened this morning. Barry has pleaded not guilty to all charges.

A search warrant tied to the case alleges that Barry told investigators she’d just left a theme party at the Candlelight Tavern on South Pearl Street in Denver and repeatedly asked at the scene if everyone in her car was OK.

Barry was driving alone

“She remembered getting into her car and … somehow getting on the highway, and then being surrounded by firemen,” wrote Daniel Kimmett, a senior investigator for the Denver District Attorney’s Office.

Officers noted Barry’s eyes “were bloodshot and watery” and her speech slurred.

Barry, who has no history of DUI in Colorado court records, tested at a .219 blood alcohol content, police say.

Duncan, 31, died at the scene and two others allegedly struck by Barry were sent to the hospital with non-life threatening injuries.

KKTV in Colorado Springs has reported that Duncan’s death orphaned her now teenage daughter. The girl’s father died four years ago.

Duncan’s mother, Diana Smith, has filed suit against Barry in civil court for wrongful death.

Jessica Fender: 303-954-1244 or jfender@denverpost.com