"If this election is about how we're going to fight to get nothing done, then ... I don't want any part of it," he said, according to CNN

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"I've got a lot of really cool things I could do other than sit around, being miserable, listening to people demonize me and me feeling compelled to demonize them. That is a joke. Elect Trump if you want that," he said.

The comment drew one of the biggest responses during the event from the crowd of about 500, twice the amount he normally attracts on the trail, according to CNN.

The event was headlined by Sen. Tim Scott (R-S.C.) and Rep. Trey Gowdy (R-S.C.), who led the day-long Benghazi hearing Thursday.

Trump is currently dominating among Republican candidates in South Carolina, with 36 percent support compared to Bush's 6 percent, according to a recent CNN/ORC poll.

Trump mocked Bush's recent decision to lay off staffers and cut salaries Saturday, but Bush also mocked Trump back.

"There's a lot of big personalities on the stage. A lot of them. One in particular," he said, mocking one of Trump's favorite words. "Huge, huge, huge!"