Dosage (oral)

Threshold : 0.5 - 1 mg

Light : 1 - 2 mg

Common : 3 - 5 mg

Strong : 8 - 10 mg

Heavy : 10+ mg

Duration (oral)

Total Duration : 12 - 16 hours

Onset : 20 - 90 minutes

Come up : 1 - 2 hours

Peak : 8 - 12 hours

Come down : 1 - 3 hours

After effects : 2 - 4 hours

2,5-Dimethoxy-4-methylamphetamine (DOM) or STP is a psychedelic drug of the substituted phenethylamine and substituted amphetamine chemical classes. It is a member of the DOx family of compounds. The phenethylamine equivalent (lacking the alpha-methyl group) is 2C-D.

This substance was first used recreationally in the mid-1960s and has little to no history of human usage prior to the 1991 publication of its synthesis and pharmacology in the PiHKAL (Phenethylamines i Have Known And Loved) by Alexander Shulgin. In modern times, it is used as a recreational drug and an entheogen, rarely sold on the streets and almost exclusively obtained as a grey area research chemical through the use of online vendors.

In terms of its pharmocology, DOM acts as a selective 5-HT2A, 5-HT2B, and 5-HT2C receptor partial agonist. Its psychedelic effects are mediated via its actions on the 5-HT2A receptor. Due to its selectivity, DOM is often used in scientific research when studying the 5-HT2 receptor subfamily.

DOM is a highly dose sensitive psychedelic that is often sold on blotting paper and known for its strong visuals and intense body load. Many reports also indicate that the effects of this chemical may be overly intense for those who are not already experienced with psychedelics.

The DOC experience contains a complex and wide array of effects which based on the predefined potential subjective effects index found here, I will now begin to breakdown and describe.

Physical effects:



The physical effects of DOM can be broken down into six components all of which progressively intensify proportional to dosage. These are described below and generally include:

Spontaneous tactile sensations - The body high of DOM is manifested as somewhat intense in comparison to most classical psychedelics, however in comparison to DOC and the overwhelming forcefulness of 2C-E, it can actually be considered quite mild. The sensation itself can be described as a constantly present yet somewhat mild energetic pins and needles sensation that encompasses a person’s entire body. This is coupled with a euphoric, fast moving, sharp and location specific tingling sensation. It is usually felt over every square inch of the skin but occasionally manifests itself in the form of a continuously shifting tingling sensation that travels up and down the body in spontaneous waves.

- The body high of DOM is manifested as somewhat intense in comparison to most classical psychedelics, however in comparison to DOC and the overwhelming forcefulness of 2C-E, it can actually be considered quite mild. The sensation itself can be described as a constantly present yet somewhat mild energetic pins and needles sensation that encompasses a person’s entire body. This is coupled with a euphoric, fast moving, sharp and location specific tingling sensation. It is usually felt over every square inch of the skin but occasionally manifests itself in the form of a continuously shifting tingling sensation that travels up and down the body in spontaneous waves. Stimulation - In terms of its effects on the physical energy levels of the tripper, DOM is usually considered to be extremely stimulating at levels which do not become overwhelming, resulting in a shakiness and unsteadiness of the hands but encouraging trippers to move around, run, dance, climb and generally engage in physical activities. In comparison, other more commonly used psychedelics such as psilocin are generally sedating and relaxed.

- In terms of its effects on the physical energy levels of the tripper, DOM is usually considered to be extremely stimulating at levels which do not become overwhelming, resulting in a shakiness and unsteadiness of the hands but encouraging trippers to move around, run, dance, climb and generally engage in physical activities. In comparison, other more commonly used psychedelics such as psilocin are generally sedating and relaxed. Increased bodily control

Enhancement of touch - Feelings of enhanced tactile sensation are consistently present at moderate levels throughout most DOM trips. Once Level 7A visuals are reached, an intense sensation of suddenly becoming aware of and being able to feel every single nerve ending across a person’s entire body all at once is consistently present.

- Feelings of enhanced tactile sensation are consistently present at moderate levels throughout most DOM trips. Once Level 7A visuals are reached, an intense sensation of suddenly becoming aware of and being able to feel every single nerve ending across a person’s entire body all at once is consistently present. Nausea - Mild to extreme nausea are reported when consumed in moderate to high dosages and either passes once the tripper has vomited or gradually fades by itself as the peak sets in.

- Mild to extreme nausea are reported when consumed in moderate to high dosages and either passes once the tripper has vomited or gradually fades by itself as the peak sets in. Vasoconstriction - This effect is usually only present at higher dosages but can be particularly uncomfortable.

Cognitive effects:

The head space of DOM is described by many as one of extreme mental stimulation and a powerful enhancement of a person’s current mental state.

The total sum of these cognitive components regardless of the setting generally includes:

Introspection - This component is consistently manifested only in the context of a non-social setting in which the user is alone.

- This component is consistently manifested only in the context of a non-social setting in which the user is alone. Increased empathy, love and sociability - This component is consistently manifested only in the context of social settings in which one is within the company of others. These feelings of sociability, love and empathy are a little weaker and less sharp than those found on substances such as MDMA and 2C-B but still prove strong enough to provide long lasting therapeutic effects.

- This component is consistently manifested only in the context of social settings in which one is within the company of others. These feelings of sociability, love and empathy are a little weaker and less sharp than those found on substances such as MDMA and 2C-B but still prove strong enough to provide long lasting therapeutic effects. Acceleration of thought

Time distortion

Feelings of fascination, importance and awe

Conceptual thinking

Connectivity of thought

Enhancement of current mind state

Removal of cultural filter

Ego suppression, loss and death

Visual effects:

Enhancements

DOM presents a full and complete array of possible visual enhancements which generally includes:

Increased visual acuity

Enhancement of colours

Enhanced pattern recognition

Distortions

As for visual distortions and alterations, the effects experienced are detailed below:

Visual drifting (melting, flowing, breathing and morphing) - In comparison to other psychedelics, this effect can be described as highly detailed, slow and smooth in motion, static in their appearance and unrealistic/cartoon like in style.

(melting, flowing, breathing and morphing) - In comparison to other psychedelics, this effect can be described as highly detailed, slow and smooth in motion, static in their appearance and unrealistic/cartoon like in style. Tracers

After images

Texture repetition

Colour shifting

Scenery slicing

Geometry

The visual geometry that is present throughout this trip can be described as more similar in appearance to that of 4-AcO-DMT or ayahuasca than that of LSD, 2C-B or 2C-I. They can be comprehensively described as structured in their organization, organic in geometric style, intricate in complexity, large in size, fast and smooth in motion, colourful in scheme, glossy in color, sharp in their edges and equally rounded and angular in their corners. They give off a contradictory natural and synthetic feel to them that at higher dosages are significantly more likely to result in states of Level 7B visual geometry over Level 7A.

Hallucinatory states

DOM and other substituted amphetamines produce a full range of high level hallucinatory states in a fashion that is more consistent and reproducible than that of many other commonly used psychedelics. This holds particularly true in comparison to other substances within the phenethylamine family. These effects include:

External hallucinations

Internal hallucinations - In comparison to other psychedelics such as LSD, DOM is extremely high in imagery embedded within visual geometry. This particular effect commonly contains hallucinations with scenarios, settings, concepts and autonomous entity contact. They are more common within dark environments and can be described as internal in their manifestation, lucid in believability, interactive in style and almost exclusively of religious, spiritual, mystical or a transcendental nature in their overall theme.

Auditory effects:

The auditory effects of DOM are common in their occurrence and exhibit a full range of effects which commonly includes:

Enhancements

Distortions

Hallucinations

Health effects, addiction potential and tolerance:

The toxicity and long term health effects of recreational DOM have been studied in a very limited amount of scientific context and the exact toxic dosage is unknown. This is because DOM is a research chemical with very little history of human usage. Anecdotal evidence from people who have tried DOM within the psychedelic community suggests that there are no negative health effects attributed to simply trying this drug at low to moderate doses or using it very sparingly (but nothing can be completely guaranteed).

DOM is not physically addictive and many users experience a frequency self-regulating quality to the drug. Tolerance for DOM seems to be very mild and does not build up without repeated use over a short period of time.

Legal issues:

UK: DOM is a Class A drug.

DOM is a Class A drug. USA: DOM is a Schedule I drug.

DOM is a Schedule I drug. Canada: DOM is a Schedule I drug.

DOM is a Schedule I drug. New Zealand: DOM is a Class C drug.

DOM is a Class C drug. Belgium: DOM is a Schedule I drug.

Conclusion:

In conclusion, DOM is a very worthwhile compound and I was intrigued by its ease in ability to invoke higher level visual and cognitive effects. It deserves its place in Shulgin’s magical half dozen and (while long-lasting) is definitely one of the more interesting and unique phenethylamines I have tried.

This substances subjective effect breakdown was contributed by PsychonautWiki admin, Cocoanatta.