Mayor Bill de Blasio has a message for people partying on the Lower East Side — keep it down out there.

Like an angry neighbor rapping on the ceiling with a broomstick, hizzoner told tipsy revelers Tuesday to turn down the volume on the good times as they bar hop along Ludlow and Orchard streets.

“The world loves New York nightlife, but we also have to take care of the New Yorkers who live where others play,” said de Blasio as he announced a new nightlife crackdown in the once gritty neighborhood, which is now home to numerous multi-million condos.

“We don’t want noise in the middle of the night that’s not fair to the community,” added mayor said before joining his nightlife czar Ariel Palitz for a beer.

De Blasio made the announcement at the legendary Max Fish bar on Orchard Street, a 30-year-old venue where poor artists and skate punks once rubbed elbows and shot pool with celebrities like Johnny Depp and James Gandolfini.

Today it sits across from a boutique that sells $170 cotton pajamas.

The new push for peace and quiet — dubbed the “Night Owl etiquette campaign” — includes more “no standing zones” to reduce traffic congestion and noise, additional street cleaning, and a public relations push to make sure the masses are on the best behavior in the wealthy and gentrified nabe.

PSAs will “urge patrons to use common-sense nightlife consideration including keeping sound to a minimum and keeping sidewalks clean and clear.”

“Your night out is someone’s night in,” reads one ad.

LES resident Alyson Palmer, who is in the pop rock band Betty, said she’s sick of “walking over people sleeping it off” on her way to church on the weekends.

Darin Rubell, who owns several bars around the city, said he embraces the mayor’s plan but reminded people that his establishments are communities of their own.

“I know we can be rowdy sometimes but people really come to this establishment to celebrate a new job, cry when they get fired, meet their new wife, divorce their new life. It is though it really shows there’s a real community within all of these walls,” Rubell said.

A group of protesters welcome de Blasio when he arrived for the event 20 minutes late.

Morgan Flores, a community organizer with The Black Institute, said the city’s helping clean up the Lower East Side while ignoring neighborhoods like Jackson Heights and Flatbush that have many minority-owned businesses.

“Black business are being shut down and they’re being fined out of existence,” Flores said. “People are losing their livelihoods, their savings and their retirement and there’s no help,” she said.