A four-car crash in Sydney's north-west has sent one person flying through a car and three people to hospital in a serious and critical condition.

Four vehicles collided about 4.50 pm on Church street in Ryde, about 15 kilometres north of the city centre.



Three people were seriously injured.

Four-car crash: Three people taken to hospital. Credit:Channel Seven

The driver of one vehicle, a 35-year-old local man, was taken to Westmead Hospital by CareFlight in an ambulance, after being freed from the car.

He suffered critical head injuries and multiple fractures.



CareFlight specialists placed him in a coma and gave him a blood transfusion at the scene of the accident before taking him to hospital.



He remains in a critical condition.