After defending her mother to Margaret Cho, Bristol Palin now has fighting words for Kathy Griffin.

While hosting the December 3 VH1 "Divas Salute the Troops" concert, the 50-year-old comedian took a jab at Palin, saying that the former "Dancing With the Stars" competitor "is the only contestant in the history of the show to actually gain weight ... She gained, like, 30 pounds a week. I swear to God, it was fantastic. She's like the white Precious."

The crowd booed Griffin - and clearly, they weren't the only ones who failed to find the humor in her wisecracks.

In a statement to Fox News, 20-year-old Palin said, "The audience's reaction to this ‘comedian’ spoke volumes, and the decent people I know would probably have booed her, too. I hope people didn't have to pay money to hear her negativity and criticisms.”

As Marquee previously reported, Griffin's fellow comic Cho also had harsh words for Palin, alleging that Sarah Palin forced her daughter to do "DWTS" so the public would forget Bristol's notoriety as a teen mom and the former governor of Alaska would gain fans if she runs for president in 2012. Bristol has denied those claims.