Padalecki, 33, has never been shy about his personal life.

Earlier this year, the hunky actor discussed his struggle with anxiety and depression with E! News, saying that as a young Hollywood newbie he dealt with stress by "working and [keeping] my head down. Just work, work, work. Read, study, go to class. Go to auditions, meet with agents. And finally it all caught up."

Since then, Jared says he's "really trying to focus lately on enjoying the here and now," and he recently launched a charity T-shirt campaign to benefit mental health organization To Write Love On Her Arms.

Supernatural die-hards are currently looking forward to seeing Padalecki's return to the small screen when season 11 of the popular series premieres Oct. 7 on the CW.