A prominent Texas medical school will stop considering race or ethnicity in deciding whether to admit applicants, as part of an agreement with the Education Department’s civil rights office.

The president of the Texas Tech University Health Sciences Center signed the agreement in February, 14 years after the department began investigating a complaint filed by an anti-affirmative action group. The agreement is the first of its kind for the Education Department under Secretary Betsy DeVos, and comes as the Trump administration continues its hard turn against the use of race in admissions.

Roger Clegg, general counsel for the Center for Equal Opportunity, which filed the original complaint, said on Tuesday that the agreement could pave the way for similar actions at other schools.

“It shows that the Trump administration is serious about enforcing the civil rights laws in a way that protects the rights of all Americans to be free from discrimination,” Mr. Clegg said. “The more schools that stop using racial preferences, the harder it will be for other schools to continue using racial preferences.”