New York City’s political elite have spent days attacking Anthony D. Weiner’s increasingly embattled mayoral campaign. On Sunday, it was Washington’s turn.

Hours after his campaign manager quit in the wake of new revelations about his online conduct, Mr. Weiner found himself assailed by a parade of prominent political figures who called on the candidate to exit the race.

“At this point, it’s absurd,” David Axelrod, a former senior adviser to President Obama, said during an appearance on “Meet the Press” on NBC, which devoted a segment to Mr. Weiner’s scandal between reports on the American economy and tumult in Egypt.

“He is not going to be the next mayor of New York; he is wasting time and space,” added Mr. Axelrod, who had no qualms about his animus toward Mr. Weiner. “It’s time for him to go away and let New York have its mayor’s race.”