Anastassiadis K.

Rostovskaya M.

Lubitz S.

Weidlich S.

Stewart A.F. Precise conditional immortalization of mouse cells using tetracycline-regulated SV40 large T-antigen. Genesis. 48 : 220-232 View in Article PubMed

Google Scholar

Ashburner M.

Ball C.A.

Blake J.A.

Botstein D.

Butler H.

Cherry J.M.

Davis A.P.

Dolinski K.

Dwight S.S.

Eppig J.T.

et al.

The Gene Ontology Consortium Gene ontology: tool for the unification of biology. Nat. Genet. 25 : 25-29 View in Article Scopus (21095)

PubMed

Crossref

Google Scholar

Bar-Nur O.

Verheul C.

Sommer A.G.

Brumbaugh J.

Schwarz B.A.

Lipchina I.

Huebner A.J.

Mostoslavsky G.

Hochedlinger K. Lineage conversion induced by pluripotency factors involves transient passage through an iPSC stage. Nat. Biotechnol. 33 : 761-768 View in Article Scopus (77)

PubMed

Crossref

Google Scholar

Carey B.W.

Markoulaki S.

Hanna J.

Saha K.

Gao Q.

Mitalipova M.

Jaenisch R. Reprogramming of murine and human somatic cells using a single polycistronic vector. Proc. Natl. Acad. Sci. USA. 106 : 157-162 View in Article Scopus (375)

PubMed

Crossref

Google Scholar

Chang G.

Gao S.

Hou X.

Xu Z.

Liu Y.

Kang L.

Tao Y.

Liu W.

Huang B.

Kou X.

et al. High-throughput sequencing reveals the disruption of methylation of imprinted gene in induced pluripotent stem cells. Cell Res. 24 : 293-306 View in Article Scopus (36)

PubMed

Crossref

Google Scholar

Chen J.

Gao Y.

Huang H.

Xu K.

Chen X.

Jiang Y.

Li H.

Gao S.

Tao Y.

Wang H.

et al. The combination of Tet1 with Oct4 generates high-quality mouse-induced pluripotent stem cells. Stem Cells. 33 : 686-698 View in Article Scopus (23)

PubMed

Crossref

Google Scholar

Eguchi A.

Wleklinski M.J.

Spurgat M.C.

Heiderscheit E.A.

Kropornicka A.S.

Vu C.K.

Bhimsaria D.

Swanson S.A.

Stewart R.

Ramanathan P.

et al. Reprogramming cell fate with a genome-scale library of artificial transcription factors. Proc. Natl. Acad. Sci. USA. 113 : E8257-E8266 View in Article Scopus (12)

PubMed

Crossref

Google Scholar

Ferri A.L.

Cavallaro M.

Braida D.

Di Cristofano A.

Canta A.

Vezzani A.

Ottolenghi S.

Pandolfi P.P.

Sala M.

DeBiasi S.

Nicolis S.K. Sox2 deficiency causes neurodegeneration and impaired neurogenesis in the adult mouse brain. Development. 131 : 3805-3819 View in Article Scopus (468)

PubMed

Crossref

Google Scholar

Hogan B.

Costantini F.

Lacy E. Manipulating the Mouse Embryo: A Laboratory Manual. Cold Spring Harbor Laboratory Press , View in Article Google Scholar

Hou P.

Li Y.

Zhang X.

Liu C.

Guan J.

Li H.

Zhao T.

Ye J.

Yang W.

Liu K.

et al. Pluripotent stem cells induced from mouse somatic cells by small-molecule compounds. Science. 341 : 651-654 View in Article Scopus (805)

PubMed

Crossref

Google Scholar

Jerabek S.

Ng C.K.

Wu G.

Arauzo-Bravo M.J.

Kim K.P.

Esch D.

Malik V.

Chen Y.

Velychko S.

MacCarthy C.M.

et al. Changing POU dimerization preferences converts Oct6 into a pluripotency inducer. EMBO Rep. 18 : 319-333 View in Article Scopus (14)

PubMed

Crossref

Google Scholar

Kuleshov M.V.

Jones M.R.

Rouillard A.D.

Fernandez N.F.

Duan Q.

Wang Z.

Koplev S.

Jenkins S.L.

Jagodnik K.M.

Lachmann A.

et al. Enrichr: a comprehensive gene set enrichment analysis web server 2016 update. Nucleic Acids Res. 44 : W90-W97 View in Article Scopus (1474)

PubMed

Crossref

Google Scholar

Kumar L.

E Futschik M. Mfuzz: a software package for soft clustering of microarray data. Bioinformation. 2 : 5-7 View in Article PubMed

Crossref

Google Scholar

Liu L.

Luo G.Z.

Yang W.

Zhao X.

Zheng Q.

Lv Z.

Li W.

Wu H.J.

Wang L.

Wang X.J.

Zhou Q. Activation of the imprinted Dlk1-Dio3 region correlates with pluripotency levels of mouse stem cells. J. Biol. Chem. 285 : 19483-19490 View in Article Scopus (206)

PubMed

Crossref

Google Scholar

Loh Y.-H.

Wu Q.

Chew J.-L.

Vega V.B.

Zhang W.

Chen X.

Bourque G.

George J.

Leong B.

Liu J.

et al. The Oct4 and Nanog transcription network regulates pluripotency in mouse embryonic stem cells. Nat. Genet. 38 : 431-440 View in Article Scopus (1780)

PubMed

Crossref

Google Scholar

Malik V.

Glaser L.V.

Zimmer D.

Velychko S.

Weng M.

Holzner M.

Arend M.

Chen Y.

Srivastava Y.

Veerapandian V.

et al. Pluripotency reprogramming by competent and incompetent POU factors uncovers temporal dependency for Oct4 and Sox2. Nat. Commun. 10 : 3477 View in Article Scopus (10)

PubMed

Crossref

Google Scholar

Marthaler A.G.

Adachi K.

Tiemann U.

Wu G.

Sabour D.

Velychko S.

Kleiter I.

Schöler H.R.

Tapia N. Enhanced OCT4 transcriptional activity substitutes for exogenous SOX2 in cellular reprogramming. Sci. Rep. 6 : 19415 View in Article Scopus (6)

PubMed

Crossref

Google Scholar

Masui S.

Nakatake Y.

Toyooka Y.

Shimosato D.

Yagi R.

Takahashi K.

Okochi H.

Okuda A.

Matoba R.

Sharov A.A.

et al. Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells. Nat. Cell Biol. 9 : 625-635 View in Article Scopus (797)

PubMed

Crossref

Google Scholar

Nagy A.

Gócza E.

Diaz E.M.

Prideaux V.R.

Iványi E.

Markkula M.

Rossant J. Embryonic stem cells alone are able to support fetal development in the mouse. Development. 110 : 815-821 View in Article PubMed

Google Scholar

Nakagawa M.

Koyanagi M.

Tanabe K.

Takahashi K.

Ichisaka T.

Aoi T.

Okita K.

Mochiduki Y.

Takizawa N.

Yamanaka S. Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts. Nat. Biotechnol. 26 : 101-106 View in Article Scopus (2000)

PubMed

Crossref

Google Scholar

Okita K.

Matsumura Y.

Sato Y.

Okada A.

Morizane A.

Okamoto S.

Hong H.

Nakagawa M.

Tanabe K.

Tezuka K.

et al. A more efficient method to generate integration-free human iPS cells. Nat. Methods. 8 : 409-412 View in Article Scopus (1024)

PubMed

Crossref

Google Scholar

Okita K.

Yamakawa T.

Matsumura Y.

Sato Y.

Amano N.

Watanabe A.

Goshima N.

Yamanaka S. An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells. Stem Cells. 31 : 458-466 View in Article Scopus (329)

PubMed

Crossref

Google Scholar

Pasini D.

Cloos P.A.C.

Walfridsson J.

Olsson L.

Bukowski J.P.

Johansen J.V.

Bak M.

Tommerup N.

Rappsilber J.

Helin K. JARID2 regulates binding of the polycomb repressive complex 2 to target genes in ES cells. Nature. 464 : 306-310 View in Article Scopus (384)

PubMed

Crossref

Google Scholar

Redmer T.

Diecke S.

Grigoryan T.

Quiroga-Negreira A.

Birchmeier W.

Besser D. E-cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming. EMBO Rep. 12 : 720-726 View in Article Scopus (208)

PubMed

Crossref

Google Scholar

Reményi A.

Lins K.

Nissen L.J.L.J.

Reinbold R.

Schöler H.R.

Wilmanns M. Crystal structure of a POU/HMG/DNA ternary complex suggests differential assembly of Oct4 and Sox2 on two enhancers. Genes Dev. 17 : 2048-2059 View in Article Scopus (260)

PubMed

Crossref

Google Scholar

Rojas A.

Kong S.W.

Agarwal P.

Gilliss B.

Pu W.T.

Black B.L. GATA4 is a direct transcriptional activator of cyclin D2 and Cdk4 and is required for cardiomyocyte proliferation in anterior heart field-derived myocardium. Mol. Cell. Biol. 28 : 5420-5431 View in Article Scopus (87)

PubMed

Crossref

Google Scholar

Shu J.

Zhang K.

Zhang M.

Yao A.

Shao S.

Du F.

Yang C.

Chen W.

Wu C.

Yang W.

et al. GATA family members as inducers for cellular reprogramming to pluripotency. Cell Res. 25 : 169-180 View in Article Scopus (29)

PubMed

Crossref

Google Scholar

Sommer C.A.

Stadtfeld M.

Murphy G.J.

Hochedlinger K.

Kotton D.N.

Mostoslavsky G. Induced pluripotent stem cell generation using a single lentiviral stem cell cassette. Stem Cells. 27 : 543-549 View in Article Scopus (464)

PubMed

Crossref

Google Scholar

Stadtfeld M.

Apostolou E.

Akutsu H.

Fukuda A.

Follett P.

Natesan S.

Kono T.

Shioda T.

Hochedlinger K. Aberrant silencing of imprinted genes on chromosome 12qF1 in mouse induced pluripotent stem cells. Nature. 465 : 175-181 View in Article Scopus (606)

PubMed

Crossref

Google Scholar

Stadtfeld M.

Apostolou E.

Ferrari F.

Choi J.

Walsh R.M.

Chen T.

Ooi S.S.

Kim S.Y.

Bestor T.H.

Shioda T.

et al. Ascorbic acid prevents loss of Dlk1-Dio3 imprinting and facilitates generation of all-iPS cell mice from terminally differentiated B cells. Nat. Genet. 44 ( ) : 398-405 View in Article Scopus (208)

PubMed

Crossref

Google Scholar

Stewart S.A.

Dykxhoorn D.M.

Palliser D.

Mizuno H.

Yu E.Y.

An D.S.

Sabatini D.M.

Chen I.S.

Hahn W.C.

Sharp P.A.

et al. Lentivirus-delivered stable gene silencing by RNAi in primary cells. RNA. 9 : 493-501 View in Article Scopus (780)

PubMed

Crossref

Google Scholar

Tan F.

Qian C.

Tang K.

Abd-Allah S.M.

Jing N. Inhibition of transforming growth factor β (TGF-β) signaling can substitute for Oct4 protein in reprogramming and maintain pluripotency. J. Biol. Chem. 290 : 4500-4511 View in Article Scopus (23)

PubMed

Crossref

Google Scholar

Tanimura N.

Saito M.

Ebisuya M.

Nishida E.

Ishikawa F. Stemness-related factor Sall4 interacts with transcription factors Oct-3/4 and Sox2 and occupies Oct-Sox elements in mouse embryonic stem cells. J. Biol. Chem. 288 : 5027-5038 View in Article Scopus (26)

PubMed

Crossref

Google Scholar

Tapia N.

Reinhardt P.

Duemmler A.

Wu G.

Araúzo-Bravo M.J.

Esch D.

Greber B.

Cojocaru V.

Rascon C.A.

Tazaki A.

et al. Reprogramming to pluripotency is an ancient trait of vertebrate Oct4 and Pou2 proteins. Nat. Commun. 3 : 1279 View in Article Scopus (44)

PubMed

Crossref

Google Scholar

Tsai S.-Y.

Bouwman B.A.

Ang Y.-S.

Kim S.J.

Lee D.-F.

Lemischka I.R.

Rendl M. Single transcription factor reprogramming of hair follicle dermal papilla cells to induced pluripotent stem cells. Stem Cells. 29 : 964-971 View in Article Scopus (66)

PubMed

Crossref

Google Scholar

Wang Y.

Chen J.

Hu J.-L.

Wei X.-X.

Qin D.

Gao J.

Zhang L.

Jiang J.

Li J.-S.

Liu J.

et al. Reprogramming of mouse and human somatic cells by high-performance engineered factors. EMBO Rep. 12 : 373-378 View in Article Scopus (72)

PubMed

Crossref

Google Scholar

Wang Y.

Misumi I.

Gu A.D.

Curtis T.A.

Su L.

Whitmire J.K.

Wan Y.Y. GATA-3 controls the maintenance and proliferation of T cells downstream of TCR and cytokine signaling. Nat. Immunol. 14 : 714-722 View in Article Scopus (56)

PubMed

Crossref

Google Scholar

Wu T.

Wang H.

He J.

Kang L.

Jiang Y.

Liu J.

Zhang Y.

Kou Z.

Liu L.

Zhang X.

Gao S. Reprogramming of trophoblast stem cells into pluripotent stem cells by Oct4. Stem Cells. 29 : 755-763 View in Article Scopus (48)

PubMed

Crossref

Google Scholar

Wu G.

Han D.

Gong Y.

Sebastiano V.

Gentile L.

Singhal N.

Adachi K.

Fischedick G.

Ortmeier C.

Sinn M.

et al. Establishment of totipotency does not depend on Oct4A. Nat. Cell Biol. 15 : 1089-1097 View in Article Scopus (69)

PubMed

Crossref

Google Scholar

Zaitoun I.

Downs K.M.

Rosa G.J.M.

Khatib H. Upregulation of imprinted genes in mice: an insight into the intensity of gene expression and the evolution of genomic imprinting. Epigenetics. 5 : 149-158 View in Article Scopus (13)

PubMed

Crossref

Google Scholar