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Many of the portraits were based on real people, while some were representations of a number of patients that physicians had encountered. Some portraits are accompanied by details of the subject, giving a tantalising glimpse into their lives. While there is information about their age, profession and the history of their skin condition, we are left to consider the psychological impact of their acne. My own relationship with my skin had a significant effect on my mental health and self-confidence. When my skin flared up, I felt reluctant to leave my bedroom.