Climate activists have glued themselves to the road and locked their arms together in Melbourne's CBD and police have started moving in.

The protesters moved in on the corner of Spencer and Collins streets in front of Southern Cross train station about 9am on Thursday, locking their arms together in pipes.

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They also glued themselves to King Street bitumen near the aquarium on Thursday morning, blocking trams and traffic.

The protesters glued themselves to King Street near the aquarium on Thursday morning. Credit: AAP

Police separated the group and started removing people at the city intersection, but the activists are still on King Street.

Outbound traffic on King Street has been closed just after Flinders Street and inbound traffic on Kings Way near the West Gate freeway is also being affected.

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Police are directing traffic.

The protests are a part of the global Extinction Rebellion movement, pushing for action on climate change.

Police acted swiftly and removed people from Spencer and Collins Streets. Credit: AAP

They were removed after chaining themselves together. Credit: AAP

Cities across Australia have been disrupted by the group's "spring rebellion", a week of action that started on Monday.