Homicide Squad detectives are appealing for public assistance to help locate Jack Harvey (left) and Mark Dixon in relation to a shooting at Point Cook last week. Credit:Victoria Police

Two men wanted over the brutal shooting of a Sydney real estate agent in Melbourne's west are thought to have fled the state and are in the NSW coastal town of Byron Bay.

Homicide squad detectives in Victoria have issued warrants for Mark Dixon, a 30-year-old who also uses the surname Murphy, and Jack Harvey, 26, who both are described as having Irish accents.

The pair are believed to be in the Byron Bay area, with police keen to speak to the men over a shooting in Point Cook in Melbourne's west last week.

Sid Morgan, a 53-year-old former detective, was shot in the face at a home in Spraypoint Drive about 11pm on Thursday.