After dreaming of a mysterious bus ride leading up a steep mountain, Yuuta Teshima wakes up in a strangely-expansive rehab center with a collection of fifteen other ultra-talented students who claim to have received the same invitations to Hope's Peak Academy as he did. The mysteries about Hiroishiya Rehabilitation Center continue to pile up until a certain cartoon bear arrives to announce the mutual killing game that he has planned for them. And as hard as they may try to resist the temptations of despair, it seems that they can never escape this Rehabilitation Program of Mutual Killing...