René Menkès was the lead designer behind projects including the Royal Bank Plaza (Toronto), the Cartier, the Guy-Favreau Complex, the National Bank of Paris in Montréal, BNP in Paris, Cathedral Square (KPMG tower), the Scotia Tower, the McGill tower and many others.

One of the last projects he worked on is the Schulich School of Music at McGill University, completed by Saucier + Perrotte with MSDL. Elsewhere in Canada, his projects include the Hilton and the Holiday Inn in Québec, Standard Life Building in Calgary, Lester B. Pearson in Ottawa and the London Convention Center.

René Menkès always recognized the value of teamwork. For him, a successful project is the result not only of good design, but also of close collaboration between architects, builders, contractors, engineers, developers, and many others. In addition to this fundamental belief in the strength of the team, René Menkès based his practice and professional relations on respect and ethics. He relied on listening, sharing, collaboration, and intelligence in his practice of architecture.

The office he occupied at the firm has now became a meeting room, respectfully and affectionately named Salle Menkes.