There is "no way to predict" at this point what will happen in the 2018 midterm elections, Republican National Committee Chairwoman Ronna Romney McDaniel said Wednesday.

"We are already laying the groundwork for get out the vote and data collection, and how we are going to turn out our universe of voters," McDaniel told Fox News' "Fox and Friends" program. "But we don't know what the major issues are going to be."

Meanwhile, the polls can't be trusted, as was shown in the 2016 presidential election, she continued.

"I do think there are indicators right now in the economy that if the economy keeps going the way it's going, that we're going to have a good midterm," McDaniel said. "We have a 16-year low in unemployment. You have 1 million new jobs created under President [Donald] Trump. I mean, labor participation rights are up. Incomes are up. These are really good indicators."

McDaniel said she has heard from voters who are frustrated because there are many agenda items, such as Obamacare repeal, that have not yet happened, but she noted that "we're only in the first quarter of the game" and there remains time to get things done. She also believes Congress is doing enough to help Trump.

"There are huge issues," said McDaniel. "The president is leading on things like deregulation, on energy independence, on national security with the great Supreme Court justice in Judge [Neil] Gorsuch. "

McDaniel also said she expects there to be many nontraditional candidates competing in the midterm elections.

"The one message that I think came out of the November election and President Trump's election is people want change in Washington," she said. "The status quo is not working."