The majority of land zoned for industrial use within the city is located along Commercial Street, between Meadow Glen Mall and the Fellsway Plaza shopping center; and to the east of Wellington Circle, between Station Landing and the Malden River.

Four smaller areas designated for industrial use are located 1) along Mystic Avenue, near the Somerville border; 2) along Boston Avenue, from Ball Square to College Avenue; 3) near the city's Department of Public Works facility, between Mystic Avenue and Mystic Valley Parkway; and 4) near the intersection of Boston Avenue and Mystic Valley Parkway.