Arsene Wenger has confirmed that a quartet of Arsenal players will miss the Premier League opener against West Ham on Sunday.

Alexis Sanchez, Danny Welbeck, Tomas Rosicky and Jack Wilshere will all miss the game at the Emirates, but only Wilshere has a serious issue.

Sanchez has been given an extended break after guiding Chile to a famous victory in the Copa America over the summer.

"Sunday will come too early but in 10 days he should be alright," Wenger said at his pre-match press conference.

Both Welbeck and Rosicky should return soon, but Wilshere could be out for up to two months after suffering a hairline fracture in his right ankle at training last week.

Arsenal injury news and suspensions Show all 6 1 /6 Arsenal injury news and suspensions Arsenal injury news and suspensions Jack Wilshere (midfielder) Has suffered a setback in his recovery from a hairline fracture of his right ankle and required surgery which will keep him out for several more weeks than expected. Arsene Wenger does not expect him back until late November at the earliest. 2015 Getty Images Arsenal injury news and suspensions Danny Welbeck (striker) Was close to a return but suffered a serious setback that requires surgery and will likely leave him out until January 2016. Has not played since April, and has been described by Wenger to be "progressing well". 2015 Getty Images Arsenal injury news and suspensions Tomas Rosicky (midfielder) Suffered a knee injury while on international duty and has been missing since the start of the season. Wenger said "it's similar to Welbeck" - meaning he could be out until the New Year. 2015 Getty Images Arsenal injury news and suspensions Mikel Arteta (midfield) Played the final 10 minutes of the win against Watford but has re-injured his ankle and will miss the Everton match. 2015 Getty Images Arsenal injury news and suspensions David Ospina (goalkeeper) Has hurt his shoulder and will not be available until the next international break Arsenal injury news and suspensions Aaron Ramsey (midfield) Pulled up in the win against Bayern Munich with a hamstring problem. Will miss the next month. Getty Images

"Jack is of course down but the good news yesterday helped him to cope with it," said Wenger after it was initially feared he faced up to two months on the sidelines.

"He just needs time to heal. The news we got yesterday was that it could be much shorter than expected because he's two weeks in a boot and then maybe after that he can practice straight away again.