Get breaking news alerts and special reports. The news and stories that matter, delivered weekday mornings.

A record 6.6 million Americans filed for unemployment benefits last week, the latest brutal reminder of the toll the coronavirus pandemic is taking on the U.S. economy.

Analysts had predicted a jobless claims total of 3 million to 6 million for the week ending March 28, after huge numbers of businesses across the country were forced to close, leaving millions of Americans out of work.

Thursday's figure eclipses even the record-shattering 3.28 million jobless claims from the week before, the first real marker of the jobless number, according to data released last week by the Department of Labor for the period ending March 21.

Still, some economists said the actual number of unemployed could be much higher, since many applicants had experienced trouble filing a claim, as state labor departments became overwhelmed.

“These are numbers that are way out of the range that we have seen,” Michelle Meyer, head of U.S. economics at Bank of America, told NBC News. “During the financial crisis, we were seeing a peak of about 650,000 [first-time applications] a week.”

Full coverage of the coronavirus outbreak

Michael Feroli, the chief U.S. economist at JPMorgan, said he had been expecting a “pretty gnarly” number. He and his colleagues forecast 3.5 million applications.

“I wouldn’t want to tell fairytales about why not to worry about it,” he said. “It’s possible we could see large numbers for a couple weeks.”

Let our news meet your inbox. The news and stories that matters, delivered weekday mornings. This site is protected by recaptcha

America’s stunning unemployment surge during coronavirus, visualized

The report includes a state-by-state breakdown of initial claims. Pennsylvania saw an increase of more than 360,000 applications for unemployment benefits. More than 180,000 Ohioans applied for the first time. Many states attributed the dramatic uptick to COVID-19, or to sectors that have suffered because of stay-at-home orders.

Analysts agree it is likely traditional economic indicators will continue to worsen, as the public health crisis continues.

On Friday, the Department of Labor will release unemployment figures for the month of March, and economists surveyed say they expect to see the economy lose around 100,000 jobs, bringing a decade of job creation to a screeching halt.

April's figure, which will include data for the worst weeks of the coronavirus pandemic, is expected to be even more brutal.

“The March report will effectively be old news,” Meyer said. “The world looked very different two weeks ago than it does today.”

Economists are doing their best to navigate new terrain, but it is difficult. When there is a downturn, they look to history and theory for guidance. But the current crisis presents unique challenges.

“Part of the economy was effectively forced to hibernate for a period of time,” Meyer said. “And it’s happened all at once.”

There really is no good analogy. While there are parallels to the 1918 influenza pandemic, it is difficult to disentangle that outbreak's effects on the U.S. economy. It was more than 100 years ago, and there is inadequate data.

Ordinarily, it takes time for the full picture of a recession to come into focus: its cause and effects, and its scale. This one is different.

Like the rest of us, economists are paying close attention to public health data and to government efforts to mitigate the virus. No one knows how long it will take to curb the coronavirus outbreak, and it is hard to forecast when there is no clear time horizon.

Download the NBC News app for full coverage of the coronavirus outbreak

“There are so many variables, a modal outlook is almost useless,” said Michael Gapen, chief U.S. economist at Barclays. “We talk about scenarios: mild, medium and heavy.”

He and his colleagues continue to study the policy response to the recession. In recent weeks, the Federal Reserve has lowered interest rates, ramped up bond-buying, and publicly committed to doing all it can to fortify the U.S. economy. Congress passed a $2 trillion fiscal package, called the Coronavirus Aid, Relief and Economic Security (CARES) Act.

The legislation provides direct payments to many Americans and extends unemployment benefits, but one open question is how effective the stopgap measures will be as the crisis continues.

"We cannot be certain of how high claims levels will go over coming weeks," said Rubeela Farooqi, chief U.S. economist at High Frequency Economics. “Given the severity of this downturn, the pace of layoffs could pick up even more as labor market conditions continue to deteriorate."

President Donald Trump announced during a press briefing on Sunday that Americans should continue to work from home and avoid restaurants for another 30 days. He also suggested he would support another round of fiscal stimulus: a $2 trillion infrastructure plan.