Physicians may consider prescribing Lyrica (pregabalin) for fibromyalgia patients who have a primary complaint of neuropathic pain, new research shows. The study, titled “ A comparison of the effectiveness of amitriptilin and pregabalin treatment in fibromyalgia patients ,” was published in the journal Northern Clinics of Istanbul . Fibromyalgia is often treated with non-standardized methods, such as the use of antidepressants, some of which have shown significant effectiveness. One such antidepressant is Elavil (amitriptyline) . Another drug that has shown efficacy in fibromyalgia treatment is Lyrica, marketed by Pfizer . Lyrica was the first drug to be approved by the U.S. Food and Drug Administration for fibromyalgia treatment. Because Lyrica acts independently of antiepileptics, antidepressants, or analgesics, it can be used safely with other drugs. While there are several approved drugs for the treatment of fibromyalgia, no one pharmacological agent can completely resolve all the symptoms of the disease. In the study, researchers set out to compare the effectiveness of two of these therapies: Elavil and Lyrica. Researchers recruited 71 women with fibromyalgia and divided them into two groups. Thirty-six patients were treated with Lyrica at a dose of 450 mg, and 35 women were treated with Elavil at a dose of 25 mg. After 12 weeks of treatment, the team assessed the patients