Two Senate Democrats came out in support on Monday of confirming CIA Director Mike Pompeo Michael (Mike) Richard PompeoOvernight Defense: Pentagon redirects pandemic funding to defense contractors | US planning for full Afghanistan withdrawal by May | Anti-Trump GOP group puts ads in military papers Overnight Defense: House Democrats unveil stopgap spending measure to GOP opposition | Bill includes .6B for new subs | Trump issues Iran sanctions after world shrugs at US action at UN Navalny calls on Russia to return clothes he was wearing when he fell ill MORE as the next secretary of State, giving him a jolt of momentum ahead of vote later this afternoon on the Senate Foreign Relations Committee.

Sens. Joe Manchin Joseph (Joe) ManchinThe Hill's Morning Report - Sponsored by Facebook - Trump, GOP allies prepare for SCOTUS nomination this week Trump meets with potential Supreme Court pick Amy Coney Barrett at White House Names to watch as Trump picks Ginsburg replacement on Supreme Court MORE (D-W.Va.) and Joe Donnelly Joseph (Joe) Simon DonnellyTrump meets with potential Supreme Court pick Amy Coney Barrett at White House Names to watch as Trump picks Ginsburg replacement on Supreme Court Momentum growing among Republicans for Supreme Court vote before Election Day MORE (D-Ind.) said they would vote for Pompeo, becoming the second and third Democrats to announce their support. Sen. Heidi Heitkamp Mary (Heidi) Kathryn HeitkampCentrists, progressives rally around Harris pick for VP 70 former senators propose bipartisan caucus for incumbents Susan Collins set to play pivotal role in impeachment drama MORE (D-N.D.) announced her support on Friday.

They would give Pompeo more than enough votes to win approval on the Senate floor, even if he gets another GOP "no" vote.

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Sen. Rand Paul Randal (Rand) Howard PaulSecond GOP senator to quarantine after exposure to coronavirus GOP senator to quarantine after coronavirus exposure The Hill's Morning Report - Sponsored by National Industries for the Blind - Trump seeks to flip 'Rage' narrative; Dems block COVID-19 bill MORE (R-Ky.) is the only Republican expected to vote against him, though Sen. John McCain John Sidney McCainCindy McCain endorses Biden: He's only candidate 'who stands up for our values' Biden says Cindy McCain will endorse him Biden's six best bets in 2016 Trump states MORE (R-Ariz.), who is battling brain cancer, is almost certain to miss the vote. Sen. Jeff Flake Jeffrey (Jeff) Lane FlakeJeff Flake: Republicans 'should hold the same position' on SCOTUS vacancy as 2016 Republican former Michigan governor says he's voting for Biden Maybe they just don't like cowboys: The president is successful, some just don't like his style MORE (R-Ariz.) is also undecided on Pompeo.

If the Senate's other 48 Republicans vote "yes," that would give Pompeo 51 votes with the three Democrats.

Sen. Angus King Angus KingGovernment watchdog recommends creation of White House cyber director position Democrats step up hardball tactics as Supreme Court fight heats up Shakespeare Theatre Company goes virtual for 'Will on the Hill...or Won't They?' MORE (I-Maine) and three Democratic senators who backed Pompeo's confirmation as CIA director remain on the fence over his confirmation as secretary of State: Claire McCaskill Claire Conner McCaskillMomentum growing among Republicans for Supreme Court vote before Election Day Democratic-linked group runs ads in Kansas GOP Senate primary Trump mocked for low attendance at rally MORE (D-Mo.), Minority Leader Charles Schumer Chuck SchumerSenate Democrats introduce legislation to probe politicization of pandemic response Schumer interrupted during live briefing by heckler: 'Stop lying to the people' Jacobin editor: Primarying Schumer would force him to fight Trump's SCOTUS nominee MORE (D-N.Y.) and Mark Warner Mark Robert WarnerIntelligence chief says Congress will get some in-person election security briefings Overnight Defense: Trump hosts Israel, UAE, Bahrain for historic signing l Air Force reveals it secretly built and flew new fighter jet l Coronavirus creates delay in Pentagon research for alternative to 'forever chemicals' House approves bill to secure internet-connected federal devices against cyber threats MORE (D-Va.).

A fourth Democratic senator who supported Pompeo for CIA director, Maggie Hassan Margaret (Maggie) HassanDemocrats step up hardball tactics as Supreme Court fight heats up Congress needs to prioritize government digital service delivery Senate Democrats demand answers on migrant child trafficking during pandemic MORE (N.H.), came out in opposition to Pompeo's nomination following the endorsements from Manchin and Donnelly.

Manchin, who like Donnelly and Heitkamp faces a challenging reelection race this fall in a state won by Trump in 2016 by double digits, noted Pompeo's "exemplary" career in offering his support.

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"After meeting with Mike Pompeo, discussing his foreign policy perspectives, & considering his distinguished time as CIA Director & his exemplary career in public service, I will vote to confirm Mike Pompeo to be our next Secretary of State," Manchin said in a tweet.

After meeting with Mike Pompeo, discussing his foreign policy perspectives, & considering his distinguished time as CIA Director & his exemplary career in public service, I will vote to confirm Mike Pompeo to be our next Secretary of State. — Senator Joe Manchin (@Sen_JoeManchin) April 23, 2018

Later on Monday, Donnelly also announced his support.

"We need a Secretary of State who will give the president an honest assessment on critical issues, including Russia, Syria, and the defeat of [the Islamic State in Iraq and Syria] ISIS. I believe Director Pompeo is capable of advancing U.S. interests and leading the State Department," Donnelly said in a statement.

Before Pompeo's nomination gets to the floor, he faces a possible historic defeat at the Senate Foreign Relations Committee.

Pompeo is expected to fail to receive a favorable recommendation from the panel during a vote scheduled for early Monday evening, where Republicans hold a one-seat majority on the committee. Paul is a member of the committee and no Democrats on the panel are supporting Pompeo.

Sen. Bob Corker Robert (Bob) Phillips CorkerHas Congress captured Russia policy? Tennessee primary battle turns nasty for Republicans Cheney clashes with Trump MORE (R-Tenn.), chairman of the Foreign Relations Committee, could either send his nomination to the floor with an unfavorable recommendation or no recommendation.

Senate Majority Leader Mitch McConnell Addison (Mitch) Mitchell McConnellPelosi: Trump hurrying to fill SCOTUS seat so he can repeal ObamaCare Senate GOP aims to confirm Trump court pick by Oct. 29: report Trump argues full Supreme Court needed to settle potential election disputes MORE (R-Ky.) could also try to discharge the nomination from committee, but that gives Democrats the leverage to potentially filibuster Pompeo because the move would require 60 votes.

This story was updated at 2:23 p.m.