Police have reopened Hwy. 402 between Strathroy and Sarnia in both directions. The major route was closed overnight and this mornings after heavy snow squalls and whiteout conditions forced vehicles off the road.

There are reports of cars having been abandoned along the highway and others that have entered ditches.

The OPP say they have attended to all affected motorists, but they say some localized lane restrictions may continue as crews work to remove approximately 50 vehicles from the ditch.

Overnight, a warming centre opened at the Wyoming Fair building in Plympton-Wyoming for stranded travellers. About 22 people used the shelter, most of them arriving by about 1 a.m.

Gary Atkinson, president of the Plympton-Wyoming Agricultural Society, said the Fair building is prepared to reopen Monday night if needed.

"We're prepared all the time," he said. "If it's deemed an emergency then boom, away they come!"

OPP Const. Ed Sanchuk is reminding drivers everywhere to take it easy.

Lakeshore Rd between Mandaumin and Camlachie Roads <a href="https://twitter.com/CountyofLambton?ref_src=twsrc%5Etfw">@CountyofLambton</a> is now open but in very poor condition. <a href="https://twitter.com/BlackburnSarnia?ref_src=twsrc%5Etfw">@BlackburnSarnia</a>. Plows are attempting to clear the <a href="https://twitter.com/hashtag/Hwy402?src=hash&ref_src=twsrc%5Etfw">#Hwy402</a> but it still remains closed between Mandaumin and Kerwood Roads. <a href="https://twitter.com/hashtag/LambtonOPP?src=hash&ref_src=twsrc%5Etfw">#LambtonOPP</a> —@OPP_WR

"Slow down. When you see snow it's as simple as that, go slow," he said.

"There's no magic to winter driving people. People are always telling me that the road and weather conditions are causing collisions. I'm here to let you know that bad driving habits cause collisions so put all the distractions away."

There were more than 180 collisions in southwestern Ontario since Saturday morning, Sanchuk said.

The region also remains under an extreme cold warning.