More than one-third of participants in the Ultimate Fighting Championship Fight Night held at the Brisbane Entertainment Centre ended the night in hospital.

Main card Australian fighters Mark Hunt, 39, and Dylan Andrews, 34, topped the long injury list coming out of Saturday's event.

Mark Hunt and Antonio 'Big Foot' Silva were both taken to hospital after their fight.

Eight of the 22 competing fighters were taken to hospital, including two rushed by ambulance to St Andrew's Hospital.

Hunt, who battled Antonio "Bigfoot" Silva in the night's heavyweight drawcard, required surgery after suffering a broken hand and face during the bout.