Dr. Fredric Brandt, a celebrity dermatologist once called the “Baron of Botox” by W magazine, died Sunday at his home in Coconut Grove, Fla. He was 65.

Frederica Burden, a spokeswoman for the Miami police, said the cause was suicide.

Susan Biegacz, a publicist for Dr. Brandt, said he had been dealing with depression for some time and had recently been “devastated” by what is widely believed to be a parody of him on the Tina Fey comedy series “Unbreakable Kimmy Schmidt,” presented by Netflix.

On the show, Martin Short portrays Dr. Sidney Grant, a wispy-haired plastic surgeon whose pneumatic features suggest experiments with Botox and facial fillers run amok.

With his own wispy blond locks and pneumatic features, Dr. Brandt was a walking commentary on age-defying treatments and the products that have flooded the market since they were introduced as medical means of treating facial wasting among AIDS patients, and that he always tried first on himself.