Disable mouse acceleration in the system before game launches [citation needed] Disable mouse acceleration in the system before game launches Open the terminal and type xinput list to look up your mouse name (the Virtual core pointer section) In Steam, go to the Bioshock Infinite launch options (Properties -> SET LAUNCH OPTIONS...) Copy the following into the text-field (replace 'MOUSENAME' with the name you got in step 1, include the quotation marks): xinput --set-prop 'MOUSENAME' 'Device Accel Profile' -1 ; %command% ; xinput --set-prop 'MOUSENAME' 'Device Accel Profile' 0 Notes This will disable mouse acceleration in your system before launching the game and enable it again when the game closes (which might take a couple of seconds). Graphical user interfaces for mouse settings (e.g. mate-mouse-properties) might not be aware of the changes. It's best not to touch them while the game is running.