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Nobody f***s with the Jesus -- a "Big Lebowski" spin-off starring the world's favorite pederast COULD ACTUALLY HAPPEN ... at least according to the guy who plays Jesus in the movie.

John Turturro was out in NYC Tuesday when we asked about the rumors that have been circulating for years -- that the Jesus will rise again -- and John told us ... a spin-off MAY be in the works.

You'll have to watch the video to decide if John's for real or not -- but let's be honest, the Jesus doesn't mess around.