A 15-year-old girl has been killed and another teenage girl has been rushed to hospital after being hit by a Lamborghini on a footpath outside a Chinese restaurant in Adelaide.

Key points: A Lamborghini driver has been charged after his car hit two 15-year-olds in Adelaide

A Lamborghini driver has been charged after his car hit two 15-year-olds in Adelaide Police said the car mounted the kerb and crashed into the front doors of a restaurant

Police said the car mounted the kerb and crashed into the front doors of a restaurant Two other men died in crashes on SA country roads on Saturday

Police said the two girls were hit while walking on the footpath in front of the House of Tien restaurant on Morphett Road, Glengowrie, about 10:00pm.

Both girls were treated by paramedics at the scene.

Sophia Naismith, 15, of Seaview Downs, died, while the other girl, a 15-year-old from Richmond, was taken to the Flinders Medical Centre with serious but not life-threatening injuries.

Sophia Naismith was on the footpath when she was hit by the car. ( Instagram )

Police said the driver of the car, a 37-year-old man from Elizabeth North, allegedly lost control of the white 2016 Lamborghini Huracan, which mounted the kerb and crashed into the front doors of the restaurant.

He has been charged with causing death by dangerous driving and causing injury by dangerous driving.

He was bailed to appear in the Adelaide Magistrates Court next month.

Police have asked anyone who witnessed the crash or saw the Lamborghini nearby to call Crime Stoppers on 1800 333 000.

The vehicle involved in the crash is listed for sale online for $328,888.

It had been at a Wintertime Snow & Shine event at the nearby Westfield Marion shopping centre before the crash.

The Lamborghini involved in the crash. ( Carsales )

'Crying and yelling' after crash

The owner of the restaurant, Kiet Tran, was cooking when he heard a "big bang".

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He then saw the dying girl in his car park and covered her with a tablecloth.

"The lady from the car was jumping out and crying and yelling — she was in shock," Mr Tran said.

"The man came out to help saying 'it's not good to touch her, we don't know [what to do]. She was face down'."

He felt bad for the girl's parents.

"I can imagine the parents … I know it's chaos in the family — I can feel it and it's really bad because I'm a father too," he said.

SA Police's acting officer in charge of the Traffic Support Branch, Damien Epps, said investigators would look at whether "the manner of driving" and speed were factors in the crash.

"We're pleading with the public to drive to the conditions, to do the right thing on the roads. It's got to stop," Acting Superintendent Epps said.

Country crashes kill two

Also on Saturday night, a 22-year-old man died when his motorcycle collided with a ute and a car at the intersection of Mount Burr Road and Delaneys Road, near Millicent, in the state's south-east.

The driver of the ute, a 25-year-old South-East man, has been charged with causing death by dangerous driving.

Acting Superintendent Epps said he allegedly failed to give way to the motorcycle.

Meanwhile, a 76-year-old man died after his car veered on the wrong side of Port Wakefield Road between Dublin and Windsor and crashed head-on with another car.

Two people from the other car were airlifted to hospital.

The state's road toll is now 59, compared with 35 at the same time last year.