In 2019, The Department of General Surgery and Surgical Specialties at the University of Modena and Reggio Emilia Medical School set out an objective: To investigate the therapeutic effect of CBD Oil administered on severe chronic skin diseases and their outcome scars [1].

20 patients with psoriasis or atopic dermatitis (eczema), aged between 20 and 80 years old took part in the trial (14 female and 6 male). All of the patients selected had been suffering from moderate or severe skin disorders for 6 months and were seeking an effective therapy. Patients were complaining of the two most common skin disorders: psoriasis, atopic dermatitis (eczema) and the resulting scars.

Patients administered CBD Oil to their skin lesions twice a day, once in the morning and once in the evening. The treatment lasted for 3 months and during this period the patients did not use any other skincare products, including steroidal creams. The following skin evaluations were conducted throughout treatment:

Hydration and trans-epidermal water loss

Elasticity

Photographic Assessments

Several questionnaires rating the severity of symptoms

The results show that all skin parameters measured in patients showed improvement, with hydration and trans-epidermalwater loss being the most prevalent. The investigators concluded that topical CBD oil administration was a safe alternative treatment with the potential to improve the quality of life of patients with some skin disorders, particularly those with an inflammatory background, such as psoriasis and eczema.

The images below are results graphs from the study showing the change in hydration and trans-epidermal water loss after 90 days of CBD use.