Colombia's James Rodriguez (C) falls next to USA's DeAndre Yedlin

James Rodriguez is nursing a shoulder injury and will miss Colombia's Copa America Group A game against Paraguay on Tuesday, the Colombian Football Federation (FCF) said.

The team captain fell awkwardly and dislocated his shoulder during Colombia's 2-0 win over hosts the United States at Santa Clara on Friday and will now be absent from the match-up at the Rose Bowl in Pasadena.

The Real Madrid midfielder is one of several leading players with injury woes at the centenary tournament including Argentina's Lionel Messi and Uruguay's Luis Suarez, but could return against Costa Rica in Houston on Saturday.

Edwin Cardona, who was a starter against the U.S. alongside James, is his possible replacement in a playmaking role.

"If I get chosen to play in that position I will do so for the benefit of my team," Cardona told reporters in Los Angeles.

Highlights of the opening game of the Copa America between USA and Colombia. Pictures courtesy of Premier Sports, watch Copa America matches live on Premie Highlights of the opening game of the Copa America between USA and Colombia. Pictures courtesy of Premier Sports, watch Copa America matches live on Premie

"Of course, we have different characteristics, with James we have more ball possession."

Rodriguez - injured midway through the second half - converted a 42nd minute penalty for Colombia's second goal against the U.S. after Cristian Zapata had given them an early lead.

Colombia lead Group A with three points, two more than Paraguay and Costa Rica who drew 0-0 on Saturday. The U.S., who face the Costa Ricans in Chicago on Tuesday, have none