The most recent weekly survey of 1,000 New York State residents, about half of them from the city, by the CUNY Graduate School of Public Health and Health Policy asked how socially connected people have felt. Just over two in five said “not at all.” That was about double the number that answered that way four weeks earlier.

Forty percent of the latest poll’s respondents said they had felt anxious more than half of the time in the past two weeks; 32 percent said they had felt depressed.

“There is this grieving of life as we once knew it that wasn’t there before, as we try to come to terms with the new reality,” said Greg Kushnick, a psychologist in Manhattan. “I’m seeing it much more in my practice. People are really starting to get more depressed. And people who are prone to depression, it’s now kicking in.”

New York City, always something different for everyone who calls it home, remains out of reach in a way that has stopped feeling temporary. City and state leaders, pressed daily for a timeline toward normalcy or a passing description of what that might look like, answer with shrugs and talk of tests and curves. The city might as well be a snow globe on a high shelf, its many riches — art collections, jazz clubs, athletes and chefs, its high-C tenors and Brooklyn DJs — unavailable.