Team Bio

Tyrone Genade

I have been keeping and breeding fish all my life and was elated to join a Nothobranchius research time in 2003. My interest in ageing began during a conference in 2001 where several ageing researchers spoke about their work. I walked out the lecture theater that day knowing what research I wanted to do.This project is a continuation of my PhD work to identify Nothobranchius proteins that change with age so we can better understand how the fish age, what about ageing kills them, and how anti-ageing interventions (like resveratrol treatment) prolong lifespan. I already have a lot of data but had to cut my work short to take up my teaching position. Now I want to get the data I need to complete my current dataset and publish the information.When I am not doing science for fun, I relax by maintaining my home aquaria, growing planted aquaria, growing & breeding orchids and playing with my 6 month old son.

I'm an Assistant Professor of Anatomy & Physiology at Northwestern College, Iowa. I research ageing, in particular, the ageing of the short-lived fish, Nothobranchius furzeri. My current research goal is to profile changes in expression of proteins known to be involved in mammalian ageing of the brain in these fish. To do this I need your help!



I hold a M.Sc. in Biochemistry and a Ph.D. in Anatomy & Cell Biology. One of my papers, Resveratrol prolongs lifespan and retards the onset of age-related markers in a short-lived vertebrate, has been cited over 500 times and my first paper on Nothobranchius aging (Annual fishes of the genus Nothobranchius as a model system for aging research) has been cited 78 times. My recent, 2014 paper (Resveratrol extends lifespan and preserves glia but not neurons of the Nothobranchius guentheri optic tectum), has been cited 7 times so far. I was born and raised in Cape Town, South Africa and now reside in Orange City, Iowa where I lecture Anatomy and Physiology to nursing students as my job and research for fun.



Protein expression profiling work began in 2013 as part of Post Doc and then ground to a halt when I took up my teaching post. I was also doing research on NT-020 and other lifespan extending compounds and am eager to get back to this research.

Alessia Montesano

Love for "brain" started during my Vet School in Naples at "Univeristà degli Studi di Napoli Federico II", in particular thanks to anatomy, neurology and neurosurgery classes, these lighted the fire for research.



After becoming DVM, I start PhD course "Model Organisms for Biomedical and Veterinary Research". It gives me the chance to combine my major interests with the study of laboratory models, used during the research, in particular focused on the comparative neuroanatomy.



My goal is find out which are the mechanisms that influence and change the brain structure and function during the aging process. Well, I would like give my contribute to help people with diseases correlated with aging.



Also, I would like to find the way to resolve the ethical issue, that involve using animals in researching, applying the 3Rs rules and helping the ethics committees to find the best combination.