Anaerobic secondary infections is taking over. This is why O2 (without antibiotics) might worsen things

Low lymphocyte count

“Immunosuppressive effects of Prevotella intermedia on in vitro human lymphocyte activation”

Cytokine-storm –

induced by IL-6 production – is a predominant cause of fatality/severity in Covid19, for which they are using several IL-6 inhibitors. But IMO, we dont want to come to this severe state. Prevotella first suppresses the immune response (as in this Chinese patient) and then induces IL-6

Papers:

2014: “ azithromycin significantly a ttenuated Prevotella intermedia LPS-induced production of IL-6 in murine macrophages” 2017: “Detection of Increased Plasma Interleukin-6 Levels and Prevalence of Prevotella copri and Bacteroides vulgatus in the Feces of Type 2 Diabetes Patients” 2017: “Furthermore, Prevotella stimulate epithelial cells to produce IL‐8, IL‐6 and CCL20, which can promote mucosal Th17 immune responses and neutrophil recruitment.”

Ground glass Opacity:

Anaerobic bacteria (Prevotella here) increased risk of developing aspiration pneumonia. Aerobic bacteria are not a risk. Fluid in lungs, something being observed frequently in #Covid19.

Papers:

Association of Cardiac Injury With Mortality

“A recent study reported that 12% of patients had COVID-19–associated acute cardiac injury, manifesting as an ejection fraction decline and troponin I elevation”

Papers linking Prevotella:

2009: “ Periodontal status and Prevotella intermedia antibody in acute coronary syndrome” – “P. intermedia invade human coronary artery endothelial cells in vitro” 1999: “Invasion of Human Coronary Artery Cells by Periodontal Pathogens“- “that specific species and strains invade coronary artery cells at a significant level.”