Police are appealing for public assistance to help locate a 14-year-old Regents Park girl missing since Friday afternoon, February 24, 2017.

The girl was at a fast food outlet in a Browns Plains shopping centre, when she left with a friend around 4.30pm on Friday.

The girl was last seen in the early hours of this morning (Sunday, February 26) near Park Road railway station.

The girl is known to use public transport- buses and trains- and is believed to have visited South Bank yesterday.

Police hold concerns for her safety and well-being due to her age and she has a medical condition.

She is described as Aboriginal, approximately 150cms tall with a slim build and long brown hair. The girl was last seen wearing a maroon t-shirt, black leggings and was carrying an Adidas satchel bag.

If you have information for police, contact Policelink by providing information using the online suspicious activity form 24hrs per day at www.police.qld.gov.au/reporting.

You can report information about crime anonymously to Crime Stoppers, a registered charity and community volunteer organisation, via crimestoppersqld.com.au 24hrs per day.