WASHINGTON—Vice President Mike Pence will lead the U.S. delegation to the Winter Olympics in South Korea next month, U.S. officials said Tuesday.

Mr. Pence is expected to be joined by Ivanka Trump, although her attendance isn’t certain, officials said. President Donald Trump plans to name other members of the U.S. delegation for the Games, which run from Feb. 9 to 25 in Pyeongchang, as soon as Wednesday.

“We...