When Schumer landed her breakout set at Comedy Central's roast of Charlie Sheen in 2012, she unleashed a brutal joke on Jackass star Steve-O about the death of his friend and co-star, Ryan Dunn, in a drunk driving accident. "I truly am—no joke—sorry for the loss of your friend Ryan Dunn," Schumer said on the dais. "I know you must have been thinking it could've been me. And I know we were all thinking, 'Why wasn't it?'" When called out on what many regarded as an insensitive remark, Schumer shrugged it off and refused to back down.

Steve-O said the joke was no big deal, but his fans erupted. He discussed the debacle, in a tongue-in-cheek fashion, on The Big J Show at KRSQ Hot 101.9. Steve-O claimed Schumer's camp called to express remorse and ask for his help soothing the hate mail. Steve-O obliged. "Hey everybody, it was a roast, you know, where people say mean things to each other on purpose. That silly little whore was just doing her job."

Schumer insisted she had no regrets, telling Laughspin, "I did ask that his fans stop with the threats of ending my life. But I did not apologize for telling that joke. I don't see the hypocrisy. I'd like to continue being a comic and alive...But I absolutely, from the bottom of my heart, continue to not give a sh*t about this. I wish him the best luck in his comedy career."

https://www.youtube.com/watch?v=lRe2Rs7LomY