Former Obama aide Bill Daley said Thursday that presumptive Democratic nominee Hillary Clinton could really stick it to Republican Donald Trump with her choice for vice presidential running-mate.

"[Al Franken] would drive Trump crazy," Daley told CNBC's "Squawk Box," arguing the comedian-turned-liberal-U.S.-senator from Minnesota, would be a good pick. "[Franken] would appeal to a lot of the [Bernie Sanders] voters. Young people, motivating them in any election, is hard to do."

While acknowledging Massachusetts Sen. Elizabeth Warren, champion of the far left, would also work in Clinton's favor, Daley made the case for Tim Kaine "as a solid former governor from a swing state [Virginia.]"

Whomever Clinton — or Trump for that matter — picks as running-mates "[won't] move the needle so much so that it's going to change the dynamic," said Daley, who was commerce secretary in the Clinton administration and White House chief of staff in President Barack Obama's first term. He is now head of U.S. operations at Swiss hedge fund Argentiere Capital.