Kiki Sanford explores how polyamines found in semen could be related to a long and healthy life

Induction of autophagy by spermidine promotes longevity



"Here, we report that administration of spermidine, a natural polyamine whose intracellular concentration declines during human ageing, markedly extended the lifespan of yeast, flies and worms, and human immune cells. "



"... In addition, spermidine administration potently inhibited oxidative stress in ageing mice."



"... we found that enhanced autophagy is crucial for polyamine-induced suppression of necrosis and enhanced longevity."





Cardioprotection and lifespan extension by the natural polyamine spermidine









spermidine feeding reduced systemic blood pressure, increased titin phosphorylation and prevented cardiac hypertrophy and a decline in diastolic function, thus delaying the progression to heart failure.



In humans, high levels of dietary spermidine, as assessed from food questionnaires, correlated with reduced blood pressure and a lower incidence of cardiovascular disease.



Our results suggest a new and feasible strategy for protection against cardiovascular disease.





Women who swallow semen from a healthy man more than twice a week enjoy great health benefits.



Scientists all agree women benefit from semen, some studies are about how bad condoms are because of keeping healthy semen away from woman.



"Fellatio (sucking his penis) may be just as effective as vaginal insemination."

NIH.gov source



Semen is wholly consumed when swallowed, compared to vaginally ejaculated semen which leaks out and is wiped away.







Scientists all agree women benefit from semen, some studies are about how bad condoms are because of keeping healthy semen away from woman."Fellatio (sucking his penis) may be just as effective as vaginal insemination."Semen is wholly consumed when swallowed, compared to vaginally ejaculated semen which leaks out and is wiped away.

Swallowing semen has ‘Anti-Aging’ benefits



Published:

Gerontology 2014;60:319–326

DOI: 10.1159/000356748

Molecular Basis of the ‘Anti-Aging’

Effect of Spermidine and Other

Natural Polyamines – A Mini-Review

Nadège Minois

School of Biology, University of St Andrews, St Andrews , UK





Key Words Spermidine · Polyamines · Longevity · Aging · Autophagy · Inflammation · Metabolism · Cell survival





Abstract



Background:

Spermidine, a naturally occurring polyamine, has recently emerged as exhibiting anti-aging properties. Its supplementation increases lifespan and resistance to stress, and decreases the occurrence of age-related pathology and loss of locomotor ability. Its mechanisms of action are just beginning to be understood.



Objectives:

An up-to-date overview of the so far identified mechanisms of action of spermidine and other polyamines on aging is presented.



Methods:

Studies of aging and of the molecular effects of polyamines in general and spermidine in particular are used to synthesize our knowledge on what molecular mechanisms spermidine and other polyamines trigger to positively affect aging.



Results:

Autophagy is the main mechanism of action of spermidine at the molecular level. However, recent research shows that spermidine can act via other mechanisms, namely inflammation reduction, lipid metabolism and regulation of cell growth, proliferation and death. It is suggested that the main pathway used by spermidine to trigger its effects is the MAPK pathway.



Conclusions:

Given that polyamines can interact with many molecules, it is not surprising that they affect aging via several mechanisms. Many of these mechanisms discovered so far have already been linked with aging and by acting on all of these mechanisms, polyamines may be strong regulators of aging.

© 2014 S. Karger AG, Basel www.karger.com/Article/Pdf/356748

Source PDF



"Swallowing Semen" article released by News-Medical.net

Possible Beneficial Effects of Consumption of Semen



...Semen also consists of a variety of proteins that have antimicrobial activity against bacteria, viruses and fungi.





Also present in the semen are mood-enhancing compounds such as cortisol, estrone, oxytocin, thyrotropin-releasing hormone, prolactin, melatonin and serotonin.



For this reason, scientists have begun studying the health benefits of semen intake, both orally and vaginally.



Some of the studies into the effects of swallowing semen are described here.



Pregnancy



In a Dutch study of women who engaged in oral sex and swallowed the semen, the researchers found that swallowing semen was associated with a lower risk of preeclampsia. One hypothesis for this is that substances in the semen adapt the mother’s immune system so that it accepts foreign proteins present in sperm, as well as in the placenta and fetus. This maintains the blood pressure at a low level and thereby reduces the preeclampsia risk.



Research has also shown that some women are infertile or miscarry due to the presence of antibodies that destroy the proteins or antigens present in their partner’s semen.



Having oral sex and swallowing the semen of the partner may help make the pregnancy safer and more successful as the woman is swallowing her partner's antigens.



Morning Sickness



Work carried out by reproductive expert and psychologist Gordon Gallup from SUNY-Albany suggests that swallowing semen could provide a cure for morning sickness. Gordon hypothesizes that pregnant women vomit as a result of their bodies rejecting genetic material in the sperm as a foreign substance, but that by swallowing and ingesting the sperm of the baby’s father, they can build up immunity.



Ovulation



In a study conducted by researchers from the University of Saskatchewan, a protein in semen was found to act on the female brain to induce ovulation and that protein is the same molecule that controls the growth, maintenance and survival of neurons. The findings suggest that semen may work as a signalling hormone that acts via the hypothalamus and pituitary gland of the female brain, which triggers the release of other hormones involved in prompting ovulation.



Hair health



Some studies have shown that semen extracted from bulls rejuvenates damaged hair. Semen has been found to contain many proteins that may well complement the protein present in hair molecules.





The article then lists all the STDs and STIs under the heading Possible disadvantages of consumption of semen.



source ...Semen also consists of a variety of proteins that have antimicrobial activity against bacteria, viruses and fungi.Also present in the semen are mood-enhancing compounds such as cortisol, estrone, oxytocin, thyrotropin-releasing hormone, prolactin, melatonin and serotonin.For this reason, scientists have begun studying the health benefits of semen intake, both orally and vaginally.Some of the studies into the effects of swallowing semen are described here.In a Dutch study of women who engaged in oral sex and swallowed the semen, the researchers found that. One hypothesis for this is that substances in the semen adapt the mother’s immune system so that it accepts foreign proteins present in sperm, as well as in the placenta and fetus. This maintains the blood pressure at a low level and thereby reduces the preeclampsia risk.Research has also shown that some women are infertile or miscarry due to the presence of antibodies that destroy the proteins or antigens present in their partner’s semen.Having oral sex and swallowing the semen of the partner may help make the pregnancy safer and more successful as the woman is swallowing her partner's antigens.Work carried out by reproductive expert and psychologist Gordon Gallup from SUNY-Albany suggests that. Gordon hypothesizes that pregnant women vomit as a result of their bodies rejecting genetic material in the sperm as a foreign substance, but that by swallowing and ingesting the sperm of the baby’s father, they can build up immunity.In a study conducted by researchers from the University of Saskatchewan, a protein in semen was found to act on the female brain to induce ovulation and that protein is the same molecule that controls the growth, maintenance and survival of neurons. The findings suggest that semen may work as a signalling hormone that acts via the hypothalamus and pituitary gland of the female brain, which triggers the release of other hormones involved in prompting ovulation.Some studies have shown that semen extracted from bulls rejuvenates damaged hair. Semen has been found to contain many proteins that may well complement the protein present in hair molecules.The article then lists all the STDs and STIs under the heading Possible disadvantages of consumption of semen.

Semen Health Benefits: It Really Does Have All The Nutrients Of A Protein Shake



How's this for your protein shake: fructose sugar, water, ascorbic acid, citric acid, enzymes, protein, zinc and more. Those are nutrients found in human male ejaculate.



New research found that numerous species consume semen for its health benefits, and human seed might as well be viable as a superfood, Discovery News reports.



Female squid, for example, consume excess sperm as if it were food. So do carrion flies, certain types of leeches, picture wing flies and other creatures.



For the first time, scientists have started tracking how these species utilize the nutrients in sperm. The study was published in the journal Biology Letters by lead author Benjamin Wegener, a researcher at Monash University in Australia.



That doesn't necessarily mean humans should start feasting during foreplay, but if we did, there are plenty of resources out there to make the experience more enjoyable.



There's "Semenology," a book dedicated for the bartender in your life who also happens to enjoy concocting semen cocktails. "Natural Harvest," on the other hand, is a collection of semen-based recipes (and is actually getting good reviews). Heck, Heather Locklear says it has anti-aging benefits.



source

Based on article By Jennifer Viegas, Discovery News



Wegener said that ejaculate consumption is well-documented among numerous species. Humans are included in that group...



According to Columbia Health, human male ejaculate contains fructose sugar, water, ascorbic acid (a.k.a. Vitamin C), citric acid, enzymes, protein, zinc and more. It reads like the list of ingredients for a protein-infused sports drink.



He agrees that the behavior can put pressure on the males, which have to balance providing enough sperm for fertilization, but perhaps not so much that females start to rely upon it as a regular "tempting meal."



Quoting Benjamin Wegener, a researcher at Monash University’s School of Biological Sciences



"As the authors point out," Tregenza added, "she might even choose to eat the sperm packets from less attractive males and use the sperm from more attractive ones for fertilizing her eggs."





Quoting Tom Tregenza, a professor of evolutionary ecology at the University of Exeter and director of research for CLES Cornwall

source

Copyright 2013 Discovery Communications LLC. published by NBC Wegener said that ejaculate consumption is well-documented among numerous species. Humans are included in that group...According to Columbia Health, human male ejaculate contains fructose sugar, water, ascorbic acid (a.k.a. Vitamin C), citric acid, enzymes, protein, zinc and more. It reads like the list of ingredients for a protein-infused sports drink.He agrees that the behavior can put pressure on the males, which have to balance providing enough sperm for fertilization, but perhaps not so much that females start to rely upon it as a regular "tempting meal."Quoting Benjamin Wegener, a researcher at Monash University’s School of Biological Sciences source "As the authors point out," Tregenza added, "she might even choose to eat the sperm packets from less attractive males and use the sperm from more attractive ones for fertilizing her eggs."Quoting Tom Tregenza, a professor of evolutionary ecology at the University of Exeter and director of research for CLES CornwallCopyright 2013 Discovery Communications LLC. published by NBC source

Based on research by lead author Benjamin Wegener PhD, a researcher at Monash University’s School of Biological Sciences

Published by the journal Biology Letters



An individual's gametes (cells of reproduction (ed.)) can represent a nourishing food source for a manipulative mate.



Here, we provide evidence of ejaculate and sperm consumption



we found that female(s)... consumed the spermatophores of their partners and directed the nutrients received into both somatic maintenance (body health (ed.)) and egg production.



Despite ejaculate consumption being well documented in nature (see reviews by 1 – 4) ...







sperm consumption is rare. Where it has been found... females may consume a portion of these ejaculates post-copulation (after intercourse (ed.)).



(see reviews by Vahed [11] and Gwynne [12]).



References



1. Gershman SN,

Mitchell C,

Sakaluk SK,

Hunt J

. 2012 Biting off more than you can chew: sexual selection on the free amino acid composition of the spermatophylax in decorated crickets. Proc. R. Soc. B 279, 2531–2538. (doi:10.1098/rspb.2011.2592)



2. Wedell N,

Tregenza T,

Simmons LW

. 2008 Nuptial gifts fail to resolve a sexual conflict in an insect. BMC Evol. Biol. 8, 7. (doi:10.1186/1471-2148-8-7)

CrossRefMedline



3. Perry JC

. 2011 Mating stimulates female feeding: testing the implications for the evolution of nuptial gifts. J. Evol. Biol. 24, 1727–1736. (doi:10.1111/j.1420-9101.2011.02299.x)

CrossRefMedline



4. Perry JC,

Rowe L

. 2008 Neither mating rate nor spermatophore feeding influences longevity in a ladybird beetle. Ethology 114, 504–511. (doi:10.1111/j.1439-0310.2008.01499.x)

CrossRefWeb of Science



11. Vahed K

. 2007 All that glisters is not gold: sensory bias, sexual conflict and nuptial feeding in insects and spiders. Ethology 113, 105–127. (doi:10.1111/j.1439-0310.2006.01312.x)

CrossRefWeb of Science



12. Gwynne DT

. 2008 Sexual conflict over nuptial gifts in insects. Annu. Rev. Entomol. 53, 83–101. (doi:10.1146/annurev.ento.53.103106.093423)

CrossRefMedlineWeb of Science Published by the journal Biology Letters source An individual's gametes (cells of reproduction (ed.)) can represent a nourishing food source for a manipulative mate.Here, we provide evidence of ejaculate and sperm consumptionwe found that female(s)... consumed the spermatophores of their partners and directed the nutrients received into both somatic maintenance (body health (ed.)) and egg production.Despite ejaculate consumption being well documented in nature (see reviews by 1 – 4) ...consumption is rare. Where itbeen found... females may consume a portion of these ejaculates(after intercourse (ed.)).(see reviews by Vahed [11] and Gwynne [12]).

Study in Austria: Compound in sperm may increase life span

London, UK -- The secret to a long life may lie in the human sperm now.



In a new study conducted by Graz University scientists in Austria, it has been found that a compound called spermidine, which is found is human sperms, could be the next step in the fight against aging.



This compound helps fight aging by slowing the process itself, and thus increases longevity in flies, mice, yeast, worms, and most importantly human blood cells, by protecting them from getting damaged.



Reversing the damage

Researchers have said that aging takes place when autophagy, that is the process of repairing or recycling the damaged cells of parts of cells, no longer happens properly. This process maintains a balance in the growth and regeneration of cells.



Their claim is strengthened by the fact that with age, the concentration of spermidine reduces in the human body.



The scientists found that adding spermidine led to suppression of various aging processes in the cells. It reduces free radicals and increases the life span of the cells.



The study and its findings

They conducted the study by applying spermidine to aging yeast cells, adding it to the diet of fruit fly and nematode worm, giving mice drinking water with spermidine in it for 200 days, and lastly comparing human blood cells treated with the compound to those which were not treated.



Research on fruit flies indicated an additional life span of 30 percent in the spermidine treated specimen than the untreated specimen.



Worms also showed a similar pattern, with an increase in life span by 15 percent.



Researcher Tony Eisenberg has called the study the "holy grail of age research".



Anti-aging pill still far-fetched

The importance of the research is unquestionable, but the claims by a British newspaper that an anti-aging pill is going to hit the markets is far from true. Even human trials cannot be seen in conceivable future.



It will take many more years of testing, short-term and long-term clinical trials, and animal studies to confirm the safety, the cost, and the side-effects of such a treatment.

source

Sperm Facts: Semen as an Anti-Aging Treatment?







But spermidine present in semen has magical anti-ageing properties that help in the repairing and recycling of damaged cells.



It also improves cell growth, fights free radicals, rejuvenates the cells and improves the quality of the cells.



Not Surprisingly, spermidine is associated with sperm, but you may not know that spermidine is present in grapefruit too.



Concentrated portion of spermidine in grapefruit makes it a potent ingredient for anti-ageing.

source Cell damage or cell degeneration is a natural process called autophagy, this cellular breakdown leads to ageing. Consumption of unhealthy foods, over exposure to the sun, smoking, drinking and stress speeds up ageing.But spermidine present in semen has magical anti-ageing properties that help in the repairing and recycling of damaged cells.It also improves cell growth, fights free radicals, rejuvenates the cells and improves the quality of the cells.Not Surprisingly, spermidine is associated with sperm, but you may not know that spermidine is present in grapefruit too.Concentrated portion of spermidine in grapefruit makes it a potent ingredient for anti-ageing.

Semen Therapy Fights Cancer

Semen reduces the risk of breast cancer "not less than 50%" in married women



Study published by the U.S. National Library of Medicine National Institutes of Health shows that "semen exposure" reduces the risk of breast cancer "not less than 50%"



Abstract



A case-control study was conducted in order to test the hypothesis that a reduced exposure to human seminal factors in the early reproductive life of women is a risk factor in breast cancer.



The relative risk of exposure to the hypothetical semen-factor deficiency is 4.7 times greater for breast-cancer patients than for the controls.



The risk of developing breast cancer within the same population in the U.S.A. is estimated as



5 times greater for women who use barrier methods (condom and other) than for women who use non-barrier contraceptive methods (diaphragm and other).



The reduction of the incidence of breast cancer by eliminating the barrier contraceptive techniques would be



not less than 50% in married women in the population.





PMID:

566883

[PubMed - indexed for MEDLINE]

source U.S. National Library of Medicine National Institutes of Health AbstractA case-control study was conducted in order to test the hypothesis that a reduced exposure to human seminal factors in the early reproductive life of women is a risk factor in breast cancer.The relative risk of exposure to the hypothetical semen-factor deficiency is 4.7 times greater for breast-cancer patients than for the controls.The risk of developing breast cancer within the same population in the U.S.A. is estimated as5 times greater for women who use barrier methods (condom and other) than for women who use non-barrier contraceptive methods (diaphragm and other).The reduction of the incidence of breast cancer by eliminating the barrier contraceptive techniques would benot less than 50% in married women in the population.PMID:566883[PubMed - indexed for MEDLINE]

The risk of developing breast cancer is 5 times greater for women deprived of semen

University of Pennsylvania School of Medicine Department of Research Medicine

A case-control study was conducted in order to test the hypothesis that a reduced exposure to human seminal factors in the early reproductive life of women is a risk factor in breast cancer.

The relative risk of exposure to the hypothetical semen-factor deficiency is 4.7 times greater for breast-cancer patients than for the controls.



When the contraceptive methods alone are taken into account, the relative risk increases up to 5.3.



About 16 percent of the women using barrier methods (condom, and other)



and 3.4 percent of women using non-barrier contraceptive methods (diaphragm, pill, IUDs, rhythm, tubal ligation, and other) would develop breast cancer.



The risk of developing breast cancer within the same population in the U.S. is 5 times greater in women who use barrier methods than in women who use non-barrier contraceptive methods.



The reduction in the incidence of breast cancer by eliminating the barrier contraceptive techniques would be not less than 50 percent in married women in the entire population.



The possibility of preventive measures within an adequate family planning program is emphasized.

source

The risk of developing breast cancer significantly decreased with a longer duration of direct exposure to human semen.

Journal of Clinical Epidemiology

Detailed analysis... showed that the risk of breast cancer increased with a longer duration of use of barrier methods (withdrawal or condom).



Conversely, the risk significantly decreased with a longer duration of use of... methods allowing a direct exposure to human semen.

source

Semen contains Selenium and Glycoproteins, powerful cancer fighters

Selenium is effective in inducing lymphocyte progression through cell cycle in cancer patients: potential mechanisms for its activity.

source

We will review the compounds with anti-tumor potential identified so far in mushrooms, including low-molecular-weight (LMW, e.g. quinones, cerebrosides, isoflavones, catechols, amines, triacylglycerols, sesquiterpenes, steroids, organic germanium and selenium) and high-molecular-weight compounds (HMW, e.g. homo and heteroglucans, glycans, glycoproteins, glycopeptides, proteoglycans, proteins and RNA-protein complexes).

source

TGFbeta cells in semen help by preventing the formation of tumors.

"As for the link to cancer, it's just possible that semen could have some effect on cancer of the cervix or ovaries. There's research showing oral delivery of TGFbeta (transforming growth factor beta), one of the key molecules in semen, can increase the number and activity of "natural killer" cells which are important in recognizing and killing aberrant cells that give rise to tumors.



An Adelaide University researcher, Dr Sarah Robertson, a leading Australian scientist working in the fertility area, is involved in animal research showing TGFbeta activates an inflammatory response in the cervix and ovaries after intercourse, which may lead to increased activity in these killer cells, guarding against cancer.

Source

Donating Semen Therapy keeps men from getting prostate cancer

A Melbourne research team led by Graham Giles, from the Cancer Council Victoria. Giles's team has found men can reduce their risk of prostate cancer through regular ejaculation.



Comparing the sexual habits of a group of 1000 men who had developed prostate cancer with 1250 who had not, they found men who ejaculated more than five times a week were a third less likely to develop prostate cancer later in life. Regular ejaculation may prevent carcinogens accumulating in the prostate gland, suggest the researchers.

Source

For those who have cancer

Feel Better

Swallowing Semen Makes You Happy



Ingredients in semen... include mood enhancers like estrone, cortisol, prolactin, oxytocin, and serotonin; a sleep enhancer, melatonin; and of course, sperm, which makes up only 1%-5%.



Female college students having unprotected sex (exposure to semen) were significantly less depressed than were those whose partners used condoms (Arch. Sex. Behav. 2002;31:289-93).



Their better moods were not just a feature of promiscuity, because women using condoms were just as depressed as those practicing total abstinence (no semen).



The benefits of semen contact also were seen in fewer suicide attempts and better performance on cognition tests (IQ tests).



So there’s a deeper bond between men and women than St. Valentine would have suspected, and now we know there’s a better gift for that day than chocolates.

source

- The journal Surgery News, February 2011 by editor-in-chief, Greenfield, of the University of Michigan, and president-elect of the American College of Surgeons .



Article - Woman Gynecologist defends Dr. Greenfield, and confirms health benefits of semen

drjudithweinstock.typepad.com

Popular Science agrees! Controversial Ideas: Does Semen Act As an Antidepressant to the Recipient?

By Jennifer Abbasi Popular Science

www.popsci.com

Psychology Today : Attention, Ladies: Semen Is An Antidepressant

seminal fluid: mostly water, plus about 50 compounds: sugar (to nourish sperm), immunosuppressants (to keep women's immune systems from destroying sperm), and oddly, two female sex hormones, and many mood-elevating compounds: endorphins, estrone, prolactin, oxytocin, thyrotrpin-releasing hormone, and serotonin.



So it appears quite possible that the antidepressants in semen might have a real mood-elevating effect.

...this effect might come in handy for women over age 50, who are experiencing menopausal blues.

Psychology Today

Improve sense of smell, reduce risk of heart disease, aid in weight loss, pain relief and soothing PMS symptoms and even help people live longer.

Then there's a study showing women are less depressed if they have sex without condoms and another showing regular sex helps to avoid colds. While the research method used for the depression study is rather shaky, both studies, Robertson says, are based on legitimate scientific reasoning.



There's also research suggesting regular sex can improve sense of smell, reduce risk of heart disease, aid in weight loss, pain relief and soothing PMS symptoms and even help people live longer.



Source

University of Saskatchewan Team unlocks link between sex, female brain. It's semen.



"An international team of scientists led by Gregg Adams at the University of Saskatchewan has discovered that a protein in semen acts on the female brain to prompt ovulation, and is the same molecule that regulates the growth, maintenance, and survival of nerve cells.



Male mammals have accessory sex glands that contribute seminal fluid to semen, but the role of this fluid and the glands that produce it are not well understood.



“From the results of our research, we now know that these glands produce large amounts of a protein that has a direct effect on the female,” says Adams, a professor of veterinary biomedical sciences at the Western College of Veterinary Medicine at the U of S.



The work, which appears in the August 20, 2012 issue of the Proceedings of the National Academy of Sciences (PNAS), raises intriguing questions about fertility in mammals, including humans.



The team characterized the protein, dubbed ovulation-inducing factor (OIF), that they have found in the semen of all species of mammal they have looked at so far. In the process of discovering its identity, the team compared OIF to thousands of other proteins, including nerve growth factor (NGF) which is found primarily in nerve cells throughout the body.



“To our surprise, it turns out they are the same molecule,” Adams says. “Even more surprising is that the effects of NGF in the female were not recognized earlier, since it’s so abundant in seminal plasma.”a protein in semen was found to act on the female brain to induce ovulation and that protein is the same molecule that controls the growth, maintenance and survival of neurons. The findings suggest that semen may work as a signalling hormone that acts via the hypothalamus and pituitary gland of the female brain, which triggers the release of other hormones involved in prompting ovulation.



University of Saskatchewan "An international team of scientists led by Gregg Adams at the University of Saskatchewan has discovered that a protein in semen acts on the female brain to prompt ovulation, and is the same molecule that regulates the growth, maintenance, and survival of nerve cells.Male mammals have accessory sex glands that contribute seminal fluid to semen, but the role of this fluid and the glands that produce it are not well understood.“From the results of our research, we now know that these glands produce large amounts of a protein that has a direct effect on the female,” says Adams, a professor of veterinary biomedical sciences at the Western College of Veterinary Medicine at the U of S.The work, which appears in the August 20, 2012 issue of the Proceedings of the National Academy of Sciences (PNAS), raises intriguing questions about fertility in mammals, including humans.The team characterized the protein, dubbed ovulation-inducing factor (OIF), that they have found in the semen of all species of mammal they have looked at so far. In the process of discovering its identity, the team compared OIF to thousands of other proteins, including nerve growth factor (NGF) which is found primarily in nerve cells throughout the body.“To our surprise, it turns out they are the same molecule,” Adams says. “Even more surprising is that the effects of NGF in the female were not recognized earlier, since it’s so abundant in seminal plasma.”a protein in semen was found to act on the female brain to induce ovulation and that protein is the same molecule that controls the growth, maintenance and survival of neurons. The findings suggest that semen may work as a signalling hormone that acts via the hypothalamus and pituitary gland of the female brain, which triggers the release of other hormones involved in prompting ovulation.

Pregnancy Preparation

"Oral sex (with semen swallowing) makes pregnancies safer."



It's true, research by Professor Gus Dekker, a maternal-fetal medicine specialist at the University of Adelaide, shows. Dekker compared 41 pregnant women with pre-eclampsia - a condition where the mother's blood pressure soars during pregnancy - to 44 without.



He found 82 per cent of those without the condition practiced fellatio compared with 44 per cent of those with it. The explanation? Semen contains a growth factor which helps persuade a mother's immune system to accept sperm. Regular exposure before pregnancy helps her immune system get used to her partner's sperm.

Source

Wikipedia: Pre-eclampsia, Treatment and prevention, Fellatio (with semen swallowing)







have reported that pre-eclampsia, a life threatening complication that sometimes arises in pregnancy, is much less frequent in couples who have practiced oral sex, and even more rare in couples where fellatio regularly ended with a woman's swallowing of her partner's semen.



The results were statistically significant and are consistent with the fact that semen contains several agents that have important roles in the prevention of pre-eclampsia, which may arise out of an immunological condition.

According to that view, pre-eclampsia is caused by a failure of the mother to accept the fetus and placenta, which both contain "foreign" proteins from the father's genes.



Regular exposure to the father's semen helps cause immunological tolerance to their proteins. Other studies also found that, while any exposure to the partner's sperm during sex appears to decrease the chances of various disorders, women in couples who have practiced "sex acts other than intercourse" are less than half as likely to suffer pre-eclampsia. It has been suggested that fellatio may, through "immune modulation", BBC News [35] have a beneficial role in preventing dangerous complications during pregnancy, reducing specifically the risk of miscarriage and pre-eclampsia. Specifically, several research groups (Koelman, CA; et al. (2000). "Correlation between oral sex and a low incidence of pre-eclampsia: A role for soluble HLA in seminal fluid?". Journal of Reproductive Immunology 46 (2): 155–166. DOI:10.1016/S0165-0378(99)00062-5. PMID 10706945.)[36] have reported that pre-eclampsia, a life threatening complication that sometimes arises in pregnancy, is much less frequent in couples who have practiced oral sex, and even more rare in couples where fellatio regularly ended with a woman's swallowing of her partner's semen.The results were statistically significant and are consistent with the fact that semen contains several agents that have important roles in the prevention of pre-eclampsia, which may arise out of an immunological condition. [35][37][38] According to that view, pre-eclampsia is caused by a failure of the mother to accept the fetus and placenta, which both contain "foreign" proteins from the father's genes.Regular exposure to the father's semen helps cause immunological tolerance to their proteins. Other studies also found that, while any exposure to the partner's sperm during sex appears to decrease the chances of various disorders, women in couples who have practiced "sex acts other than intercourse" are less than half as likely to suffer pre-eclampsia.

Wikipedia

Pregnant women who continue getting semen from the baby's father have less morning sickness

To understand where he’s coming from, we need to think back to the maternal immune system’s response to the fetus. Because half of the DNA the fetus is carrying comes from the father, the mother’s body may initially treat the organism as foreign tissue or an infection.



This response, Gallup says, triggers an immune reaction that is commonly experienced as nausea, vomiting, and malaise (aka morning sickness). The best cure for this type of sickness, says Gallup, is, strangely enough, the same thing as its cause.



The more exposure a woman has to her partner’s semen -- that is to say, the more often she’s inseminated prior to conception and during the early stages of the pregnancy -- the more tolerance her body develops to his genetic material. This tolerance generalizes to a tolerance for the fetus and leads to successful maternal immunosuppression -- and subsequently allows her to feel less like an infected zombie with serious stomach troubles.



Here is where Gallup’s reputation as an innovative -- if often highly speculative -- evolutionary theorist comes into the picture. Gallup surmises that pregnancy sickness is not itself an adaptation, but instead a side effect of a broader maternal adaptation for favoring the best possible mates. He suggests that this broader adaptation serves primarily to facilitate reproduction with males that are likely to support mother and child (in evolutionary terms, to invest in the offspring), while weeding out the players. In previous work, Gallup has shown that women are more likely to develop preeclampsia -- and thus have a higher infant mortality risk -- in pregnancies resulting from unfamiliar semen. Historically, these would have included rape and “dishonest mating strategies” (tactics in which the man lies to the woman about his long-term intentions just to get into her pants) as well as unplanned conception occurring in a new, still-fragile relationship. From the point of view of Mother Nature’s cold, cold heart, spontaneous abortions due to a reaction against unfamiliar semen might have been biologically adaptive. This is because conception and childbirth historically meant that a woman foreclosed on any other reproductive opportunities for 2 to 4 years, so pregnancies in which paternal investment was improbable would have meant an enormous gamble. Today, however, technological innovations such as barrier contraceptives (condoms reduce a woman’s exposure to semen that would otherwise become familiar) and artificial insemination mimic some ancestral conditions. The maternal immune system has no way to distinguish between, say, conception by in vitro fertilization and rape.



Still, while it may very well work wonders in curtailing nausea and vomiting in your next pregnancy, it’s probably too early to suggest imbibing copious amounts of your partner’s semen, either vaginally or orally (there is some evidence, believe it or not, that fellatio may be just as effective as vaginal insemination for priming the woman’s body with the man’s protein, activating maternal immunosuppression in preparation for a child.) Your partner might think it’s worth a shot, though.

Huffingtonpost.com source

... fellatio may be just as effective as vaginal insemination for priming the woman’s body with the man’s protein, activating maternal immunosuppression in preparation for a child.

NIH.gov source

Data from heterosexual couples, at least, indicate that women who have a history of regularly performing fellatio on males with whom they later conceive are less likely to experience histocompatibility problems during pregnancy.



They’re developing an early tolerance for a conceptus that will possess, of course, half that man’s foreign genome.



...evolutionary psychologist Gordon Gallup has recently speculated that this “seminal priming” also reduces the chances of morning sickness.



For those mothers-to-be, such as lesbians, who’d prefer not to imbibe semen straight from the tap for priming purposes, sublingual sprays that are concatenations of various immune factors mixed with the donor male’s protein have been in development for years.

- Jesse Bering

source

They’re developing an early tolerance for a conceptus that will possess, of course, half that man’s foreign genome....evolutionary psychologist Gordon Gallup has recently speculated that this “seminal priming” also reduces the chances of morning sickness.For those mothers-to-be, such as lesbians, who’d prefer not to imbibe semen straight from the tap for priming purposes, sublingual sprays that are concatenations of various immune factors mixed with the donor male’s protein have been in development for years.- Jesse Bering

Morning Sickness







Gallup, who presented his findings at the 2012 Northeastern Evolutionary Psychology Society, proposed the woman’s body initially rejects the father’s semen as an infection and reacts to it by vomiting, the NY Daily News reported.



However, the woman will become immune to the semen by swallowing it and could ebb morning sickness in subsequent pregnancies if the second child has the same father as the first.



This remedy proposes oral sex may treat one of the most troubling symptoms of pregnancy.





source

Sex is what gave you morning sickness, and it can also be what alleviates it. Gordon Gallup, a SUNY-Albany psychologist, believes in the “hair of the dog” concept when it comes to curing morning sickness — ingesting semen, specifically the impregnator’s semen, so the woman’s body can build up a tolerance to what’s already in her body.Gallup, who presented his findings at the 2012 Northeastern Evolutionary Psychology Society, proposed the woman’s body initially rejects the father’s semen as an infection and reacts to it by vomiting, the NY Daily News reported.However, the woman will become immune to the semen by swallowing it and could ebb morning sickness in subsequent pregnancies if the second child has the same father as the first.This remedy proposes oral sex may treat one of the most troubling symptoms of pregnancy.

Donating Semen Therapy to a woman to swallow four (4) hours before intercourse increases the quality of sperm.





The couple should have intercourse again four (4) hours later, if the man can be enticed to perform it.





In general, total motile spermatozoa as well as actively motile spermatozoa progressively increased from first to last ejaculate at the cost of sluggish spermatozoa. A significant increase in seminal plasma calcium and magnesium was seen as well as a significant increase in magnesium inside the cell from the first to the fourth ejaculate. Women who are trying to get pregnant should swallow an ejaculation first, then four (4) hours later receive the improved sperm by intercourse.The couple should have intercourse again four (4) hours later, if the man can be enticed to perform it.In general, total motile spermatozoa as well as actively motile spermatozoa progressively increased from first to last ejaculate at the cost of sluggish spermatozoa. A significant increase in seminal plasma calcium and magnesium was seen as well as a significant increase in magnesium inside the cell from the first to the fourth ejaculate. source

Clear up Acne

Zinc from Semen Therapy (Zinc Alpha 2 Glycoprotein - ZAG) Clears Up Acne



A study about ZAG and shedding of skin cells: Another enzyme that we have shown to participate in desquamation of normal skin is ZAG (38) . We had previously shown that ZAG expresses enzymatic activity (44) and that it plays a role in stratum corneum cohesion (45) . ZAG also has ribonuclease activity (46) and it participates in the destruction of nuclei in terminally differentiating keratinocytes (47)

source

Sperm contains an enzyme called Zinc-alpha2-glycoprotein ,

go all the way down to the bottom on the reference to sperm and this enzyme which is also the enzyme in the skin responsible for allowing skin cells to shed properly. It is already known that acne sufferers are a bit deficient in this specific enzyme, which is the cause of there being an excess of dead skin cells for those with acne. The dead skin cells then build up, get all glued together with oil, and block your pores. source go all the way down to the bottom on the reference to sperm and this enzyme

source

Sure, other vitamins and minerals help. But zinc does the heavy lifting . It's linked to your fertility, potency, sex drive and long-term sexual health. The mineral is critical to sperm production, and low zinc stores have been blamed for decreases in semen volume and testosterone levels, explains Sara Brewer, M.D., author of Better Sex. "Each ejaculation can expend up to 5 milligrams of zinc, or one-third of your daily allowance," Dr. Brewer says. Luckily, zinc is easy to come by. Four ounces of lean beef provide half the daily requirement, and a single oyster gives you the whole shebang. Turkey, cereals and beans are other good sources.

Source

Semen has anti-microbial (antibacterial) properties; Altruins

ALTRUINS, NATURAL ANTIBIOTICS OF THE MALE GENITAL TRACT

Robert I Lehrer, Professor

Medicine University Of California Los Angeles

office Of Research Administration

Los Angeles, Ca 90095

Grant 5R01AI046015-03 from National Institute Of Allergy And Infectious Diseases IRG: REB



Abstract: Long term objectives. To discover the endogenous antimicrobial effector molecules of humans, and to define their structures and mechanisms of action. This proposal deals with antimicrobial peptides of the male genital tract, an area where remarkably little information currently exists. Hypotheses. Normal human semen contains proteins with latent antimicrobial domains that are activated by serine and aspartyl proteases found in normal semen. The resulting peptides ("altruins") can protect the female from infection by bacteria introduced into the vagina during intercourse.

source Los Angeles, Ca 90095Grant 5R01AI046015-03 from National Institute Of Allergy And Infectious Diseases IRG: REBAbstract:

Melt Fat

Obesity; Semen contains alpha 2 glycoprotein (ZAG) Could this be the cure to obesity?



UK Dailymail: British researchers are trying to develop a pill which could be used to treat obesity without the slimmer having to cut down on what they eat, it was announced.



The team at Aston University in Birmingham are looking at the role of a protein, called zinc alpha 2 glycoprotein (ZAG), which appears to promote weight loss without an obese person having to reduce their food intake.



This happens because the protein targets fat breakdown while not affecting muscle mass. Professor Mike Tisdale said their long-term plan was to try to turn ZAG into a treatment, such as a tablet, to treat obesity.



ZAG, a soluble protein, is present in most body fluids and in most normal tissues of the body. But the protein is also involved in a process called cachexia - the weight loss that happens in some cancer patients.



During cachexia, ZAG production is increased 10-fold, causing the movement of fat from adipose tissue which is used to produce heat rather than energy.



This can lead to cancer patients losing 85 per cent of their body fat. This fat mobilisation is normally linked to energy demand, so anything which disrupts this process will lead to progressive fat loss.



The process has been extensively examined by Prof Tisdale, leading him to use the protein to target obesity.



ZAG also has potential to be used to treat diabetes because it also lowers blood sugar levels.

Anti-diabetic properties of zinc-alpha2-glycoprotein

Semen Curbs Appetite

I do believe that it curbs your hunger as I found it out quite by accident. My boyfriend of 6 years and I were making love one morning and he wanted to finish in my mouth so I said sure and I swallowed it. Once we were done I got up took shower and got ready for work, I had to be there for 8a. I was running late and hadn't had time for breakfast I didn't realize I wasn't hungry until around 10a and then I sat there completely puzzled because I couldn't understand why as I hadn't had my Red Bull or Monster or Starbucks which normally curbs my appetite in the morning, I hadn't even drank any water until I remembered he only thing I had swallowed that morning was his cum. I was hungry till almost noon when I normally had lunch. I thought it was a fluke so I tried 2 more times just to be sure ( you can imagine my boyfriend was only too happy to help me conduct my experiment) so it actually does work, but I don't recommend swallowing cum on a consistent basis or running around giving every guy you meet a blow job as part of your weight loss program either. But it does work

source

Overweight woman, previously the Heaviest Woman In The World, losing hundreds of pounds through sex

CNN Video

Lesbians at higher risk for obesity: study

The Toronto Star

Reuters



WASHINGTON – Lesbians are twice as likely as heterosexual women to be overweight or obese, which puts them at greater risk for obesity-related health problems and death, U.S. researchers said.



The report, published in the American Journal of Public Health, is one of the first large studies to look at obesity among lesbians.



Ulrike Boehmer of the Boston University School of Public Health and colleagues looked at a 2002 national survey of almost 6,000 women, and found that lesbians were 2.69 times more likely to be overweight and 2.47 times more likely to be obese.



"Lesbians have more than twice the odds of (being) overweight," the authors wrote. This would put them at a higher risk for diabetes and heart disease, among other ailments.



"Our findings indicate that lesbian sexual identity is linked to a greater prevalence of overweight and obesity," the authors wrote in the study, released this week.



They reviewed smaller studies that have suggested a higher prevalence of obesity among lesbians and the possible reasons why.



"The results of these studies indicate that lesbian women have a better body image than do heterosexual women," they wrote.



But the authors said they placed little confidence in the idea that lesbians were more muscular than straight women, and thus were more likely to have a high body mass index, or BMI, while having little body fat.



High muscle mass is "unlikely to lead to classification as obese," the researchers said.



"We reported greater odds of both overweight and obesity in lesbians and we feel confident in asserting that these differences are a result of increased adiposity," the researchers wrote.

The Toronto Star Newspaper ReutersWASHINGTON –

Spermidine given to mice as a dietary supplement increased their lifespans and seemed to benefit their cardiovascular systems"...cellular activity increases, and mortality decreases. In fact, a study published in 2016 in Nature Medicine made three interesting conclusions: first, spermidine given to mice as a dietary supplement increased their lifespans and seemed to benefit their cardiovascular systems; second, in rats bred for hypertension, spermidine improved their blood pressure; and, third, humans who reported eating diets rich in spermidine-containing foods, like mushrooms, soybeans, and cheddar cheese, were more likely to have lower blood pressure and risk of cardiovascular disease.How these potentially anti-aging results are achieved is also still in question, but in addition to oxidation defense and upregulation of cell metabolism, it appears that autophagy plays a major role "...Human studies in this area are still significantly lacking. And there is a major outstanding question about the involvement of polyamines in cancer; it’s really not understood if polyamines can induce cancer or simply are a part of maintaining cancer cell proliferation. However,Pod Cast on iTunes.com Article published by ChemistryWorld.com Quoted:and: A study in Journal of Endocrinology cautions that women with cervical cancer or uterine cancer or Human Papilloma Virus (HPV) Semen 'aggravates cervical cancer' because tumors in the cervix and womb have prostaglandin receptors on their surfaces BBC news explains "But a cancer expert said the chances of unprotected sex affecting a patient's outcome was "slight"." cancercommentary.com explains "Cervical cancer is usually triggered by long-term exposure to HPV and is not caused by prostaglandins." Throat or mouth cancer would likewise be aggravated by concentrated semen swallowing.Anyone with tumors in their mouth or throat should dilute semen in a large drink.desquamation = shedding of skin cells. keratinocyte = most common type of skin cell.Also has a role in melanin production and skin cancer:Men deplete their Zinc reserves when they ejaculate. Therefore men must consume food with raw Zinc to make more Zinc Alpha 2 Glycoprotein."We are a little way off a clinical trial now and our long-term plan is to develop a suitable delivery method, perhaps a tablet, that will enable us to turn ZAG protein into a commercial treatment for obesity," Professor Tisdale said.Lesbians as a group would have significantly less exposure to semen than the average woman.The Man Juice Diet is a slang term for swallow semen from a healthy man every time you eat achieving radical weight loss and ending your obesity.