The Red Sox were off Tuesday, but they’ll get back to work Wednesday night on a day where the front office certainly was busy. The club announced a flurry of roster moves Wednesday afternoon.

Most notably was that starting pitcher John Lackey was sent to the 15-day disabled list. Lackey left Saturday’s start in Toronto with a biceps injury. Lackey and the club were hopeful that a DL trip could be avoided, but that was wishful thinking apparently. The move is retroactive to April 7.

The Sox called up right-handed pitcher Alex Wilson from Pawtucket to fill Lackey’s spot on the 25-man roster. Wilson, the club’s minor league pitcher of the year in 2011, has given up three runs in 2 2/3 innings this season with Pawtucket.

Shortstop Stephen Drew has been activated as well. He was taken off the seven-day concussion disabled list, and he’s expected to make his Red Sox debut Wednesday night against the Orioles. Drew suffered a concussion when he was hit in the head with a pitch on March 7 that caused him to miss most of spring training.

To make room for Drew on the 25-man, the Sox had to send down shortstop Jose Iglesias to Pawtucket. The slick-fielding shortstop had been a pleasant surprise in the early going. The 23-year-old was hitting .450 (9-for-20) to begin the year with the big club.