And this news couldn't have come sooner, as in the very same issue of the NEJM, another paper reported that malaria found in Cambodia has become resistant to the most effective drugs used to prevent the disease. The authors of that study believe that misuse of malaria medication gave the parasite the chance to evolve resistance. They also warned that the spread of a resistant strain of malaria could be especially dire, seeing as the disease, even with all the preventative measures already developed, is the world's third deadliest.