One cyclist is dead and another suffered life-threatening injuries after being struck from behind by a vehicle in Hamilton Sunday morning, OPP said.

Police say the cyclists were riding eastbound on Highway 5, just west of Sydenham Road in Flamborough, when the collision occurred around 11:30 a.m. Sunday.

Two men, each around 45 years old, were struck from behind by a car. One died at the scene and the other was taken to hospital.

Police expect the highway to remain closed until 4 p.m. between Millgrove Side Road and Ofield Road in both directions.

Update <a href="https://twitter.com/hashtag/Hamilton?src=hash">#Hamilton</a> <a href="https://twitter.com/hashtag/Hwy5?src=hash">#Hwy5</a> EB/WB All lanes are blocked due to a MVC. <a href="https://t.co/gl9FFUQOzG">pic.twitter.com/gl9FFUQOzG</a> —@511Ontario