A teenage boy accused of murdering his mother escaped from a California detention center early Friday morning — and is still on the loose, according to cops.

Ike Souzer, 15, managed to sneak out of his locked room and climb over a perimeter fence at the Orange County juvenile facility before fleeing on foot, cops said.

Officials noticed he was gone just after midnight following a random room check. The 6-foot tall, 200-pound teen was last seen wearing a white shirt and red pants.

“He may have a laceration to his left leg,” the Orange County Sheriff’s Office tweeted.

Souzer — described as a high-functioning autistic teen from the city of Garden Grove — has been locked up since 2017 on suspicion of killing his mother, Barbara Scheuer-Souzer.

He is accused of stabbing her multiple times with a knife and then leaving her on the ground outside their home to die.

“Due to the nature of his charges that he’s in custody for, we thought it prudent to let the citizens know who was out,” said Orange County sheriff Capt. Mike Peters at a Friday afternoon press briefing.

Officials noted how Souzer’s criminal trial was supposed to wrap up this week.

“That could be why this happened now,” said Garden Grove police Lt. Carl Whitney.

Souzer’s grandmother, Eleanor Watson, has described the boy in the past as a “volatile” person with “a temper.”

“I didn’t trust him to obey the law,” she told the Orange County Register in 2017 after Souzer’s arrest. “When he was home, he wanted to skirt the issues, but Barb laid the law down.”

Before succumbing to her wounds, cops said Scheuer-Souzer was able to identify her son as the killer. The then-13-year-old was later arrested and charged with her murder.

“Through her unconditional love and commitment, [Scheuer-Souzer] helped her son go from non-verbal to verbal status,” reads a GoFundMe page for the woman. “Her whole goal was to help her son and the autistic community by giving back and serving the needs of others.”

The Orange County Probation Department said it was assisting the sheriff’s department in the search for Souzer. The teen has connections in Orange and Riverside counties, which authorities are investigating.