Wall Street futures underlined a global market sell-off on Monday as investors fretted over the potential knock-on effects of U.S. President Donald Trump's surprise failure to deliver on health-care reform. Dow futures were set for triple-digit losses, down around 150 points at 8:45 a.m. ET, after Republicans dramatically pulled their health-care bill on Friday. "The market's patience is wearing thin," Vasileios Gkionakis, head of global FX strategy at Unicredit, told CNBC on Monday. "It definitely doubts the U.S. administration's ability to push forward (with) this so much talked and discussed agenda including the fiscal stimulus, tax deregulation, tax cuts," Gkionakis added.

'Don't call it a Trump reflation trade'

Trump's perceived inability to garner enough support from his own Republican party to repeal and replace Obamacare appeared to dent the president's image as someone who could get deals done, which prompted concern among traders for future economic policies.



"Failure to pass the health-care bill doesn't mean that President Trump's entire agenda is in tatters but it's a huge setback all the same and the market mood reflects as much," Kit Juckes, macro strategist at Societe Generale, said in a note Monday.

The depressed mood for investors was far-reaching as European markets, led by the U.K.'s FTSE 100 and German Xetra DAX, which fell over 0.7 percent. Elsewhere, Asia markets were mostly lower. The Japanese benchmark Nikkei 225 dropped by more than 1.44 percent as risk-off sentiment spurred a rush to safe-haven assets such as gold and the yen. Spot gold was trading at highs not seen for over a month as the commodity spiked to hit $1.258 an ounce.