Thousands of protesters chanting “Trump is Hitler!” stormed up Sixth Avenue en route to Trump Tower on Fifth on Wednesday night in one of many demonstrations nationwide against the new president-elect.

Those in the mob first gathered in Union Square to vent their anger over the election results.

They later took to the streets and headed to Trump’s headquarters and penthouse apartment in Midtown, where they climbed light poles and burned flags. At least 62 people were arrested, police sources said.

“That man who is not our president, we are going to make him hear us,” declared one demonstrator, 34-year-old Shannon Malone.

“There’s gonna be fallout. We’re concerned that the rights of women, the LGBTQ community, people of color will not be preserved.”

A large marching band joined the procession, as angry cabbies and other motorists who were stuck in the sudden traffic chaos honked their horns and cursed.

“This is what the popular vote looks like,” one protester noted, referring to the fact that Hillary Clinton actually beat Trump in the popular vote, despite losing the electoral vote — the only one that counts.

The president-elect was believed to be holed up in an office inside the building putting together a team of insiders who will aid in the transition and run the government in January.

A number of demonstrators were arrested for disorderly conduct, others climbed a utility pole, and one group could be seen burning an American flag.

“Donald Trump, go away. Racist, sexist, anti-gay,” the crowd shouted.

Heloïse, a 9-year-old fourth-grader whose family moved here from France, was one of the youngest protesters at the march.

“I think it’s unfair. We voted for Hillary Clinton, but it is Trump who won. It is unfair,” Heloïse said.

“We were going to go for a school trip to Washington to watch Hillary come to power in January, but now we’re not because she didn’t win.”

Protesters also gathered in Chicago, where thousands blocked the entrance to that city’s Trump Tower.

In Boston, thousands of protesters streamed through downtown, chanting “Trump’s a racist” and carrying signs that said “Impeach Trump” and “Abolish Electoral College.”

On the West Coast, people smashed windows and spray-painted anti-Trump graffiti in Oakland.

Several hundred people flooded onto one of the busiest freeways in Los Angeles, causing a miles-long traffic backup.

The protesters, who had remained peaceful and not overly disruptive for most of the night, poured onto US 101, which links downtown LA to Hollywood, and stayed there for most of an hour. Drivers sat and waited. Many got out of their cars.

There was no violence between police officers and protesters.

Back in Manhattan, protesters unleashed their rage at the states that helped elect Trump.

“F–k Florida!” and “F–k Indiana!” people shouted, along with “F–k Mike Pence!” and “F–k Giuliani!”

Protesters held signs that read “Impeach Trump,” “Don’t lose hope,” “Trump makes America hate” and “Not my president.”’

At one point, the protesters gathered in a semicircle and took turns giving reasons why they believe the Republican billionaire developer should be impeached — despite the fact that he’s not in power yet.

“Rapist,” “anti-Semitic,” “anti-LGBT,” “incest” and “KKK” were a few of the responses protesters ticked off.

“I am not happy, I have no words. This country is going to sh-t and it’s scary, I feel bad for my kids,” Nancy Gomez, 38, said through tears.

Additional reporting by Natalie Musumeci. With wires