A new direct bus service linking the city to the Perth International Airport will welcome its first passengers in two weeks.

In a first for WA, the 40-minute daily service is expected to transport 1000 commuters a day.

The trip will cost travellers up to $4.50 and will depart from the Esplanade Busport every 30 minutes during the day and will run hourly at night.

Transport Minister Dean Nalder said the route, named Airbus A380 after the world's largest passenger aircraft, was part of a broader investment into Perth's road, rail and bus networks.