House Democrats are targeting dozens of Republicans this fall, but they would especially relish defeating key incumbents hailing from California to New Hampshire.

House Minority Leader Nancy Pelosi (D-Calif.) and her lieutenants are boldly predicting they will likely win back the lower chamber. To do that, Democrats would need to pick up a net of 25 seats — which is a tall order.

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The following are 10 high-profile Republicans that Democrats would love to defeat on Election Day.

Steve King (Iowa)

Getting King’s scalp would be big for the left, which has ripped the Iowa lawmaker’s hard line on immigration. King is vying for reelection against Christie Vilsack, the wife of Agriculture Secretary Tom Vilsack Thomas James VilsackUSDA: Farm-to-school programs help schools serve healthier meals OVERNIGHT MONEY: House poised to pass debt-ceiling bill MORE. Former President Clinton has donated to the Vilsack campaign.

Sean Duffy Sean DuffyCNN's Ana Navarro to host Biden roundtable on making 'Trump a one-term president' Bottom line McCarthy blasts Pelosi's comments on Trump's weight MORE (Wis.)

The freshman won the seat previously held by former Appropriations Committee Chairman David Obey (D-Wis.). Democrats especially want this one back. Duffy’s opponent, former state Sen. Pat Kreitlow, has criticized the freshman for backing Rep. Paul Ryan Paul Davis RyanBiden's debate game plan? Keep cool and win Trump, Biden have one debate goal: Don't lose RNC chair on election: We are on track to win the White House MORE’s (R-Wis.) budget.

Ann Marie Buerkle (N.Y.)

In the 2010 wave, Buerkle defeated then-Rep. Dan Maffei (D-N.Y.), a former staffer for the House Ways and Means Committee. Maffei is now looking to reclaim the seat from Buerkle. It is unlikely Democrats will win the House unless they beat her.

Rep. Joe Walsh (Ill.)

Political handicappers have all but pegged the brash, conservative freshman as a one-hit-House-member-wonder. His re-election chances rank in the “likely Democratic” column of competitive odds-making. The outspoken, Tea Party darling of the freshman class opted not to challenge fellow GOP freshman Rep. Randy Hultgren in a nearby district earlier this year. Instead, he is battling 2006 failed Democratic House contender, Iraq war veteran Tammy Duckworth. Recent polls have showed Duckworth with nearly double-digit leads over Walsh.

Rep. Allen West (Fla.)

Defeating the blunt-spoken Tea Party-backed former Army interrogator would be a huge win for Democrats. West’s re-election bid against Democratic challenger Patrick Murphy remains in the “toss up” column of handicappers, though West is considered the favorite. On Thursday, West’s campaign released a poll to local political reporters in the Palm Beach-based district, showing him with a double-digit lead over Murphy. But Murphy has deep support in the party, evidenced by a fundraiser this month with Clinton.

Rep. Michele Bachmann Michele Marie BachmannEvangelicals shouldn't be defending Trump in tiff over editorial Mellman: The 'lane theory' is the wrong lane to be in White House backs Stephen Miller amid white nationalist allegations MORE (Minn.)

The Democratic dream to oust the 2012 White House hopeful may just be that — a dream. But the Tea Party leader will have to work hard to get reelected. Her opponent, wealthy hotel owner Jim Graves, is seeking to run as an outsider. He has acknowledged he is an underdog, but has vowed to run a “tenacious” campaign.

Rep. Dan Lungren (Calif.)

Democrats must defeat Lungren to have any hope of winning the House. Lungren beat his opponent, Ami Bera Amerish (Ami) Babulal BeraHillicon Valley: Judge's ruling creates fresh hurdle for TikTok | House passes bills to secure energy sector against cyberattacks | Biden campaign urges Facebook to remove Trump posts spreading 'falsehoods' House passes bills to secure energy sector against cyberattacks The Hill's Coronavirus Report: iBIO Chairman and CEO Thomas Isett says developing a safe vaccine is paramount; US surpasses 150,000 coronavirus deaths with roughy one death per minute MORE, by seven points two years ago. Yet, he only attracted 50.1 percent of the vote in a historic year for the GOP. Bera is back for another bid, and figures to be helped by President Obama at the top of the ticket. In their spirited debate last week, Bera and Lungren showed there is no love between them.

Rep. Chip Cravaack (Minn.)

Democrats were caught off guard when Cravaack knocked off 35-year House veteran, then-Transportation Committee Chairman Jim Oberstar in the 2010 election. David Wasserman of the Cook Political Report says that Cravaack faces obstacles: “His wife took a job in Boston and moved the family to New Hampshire so he’s splitting his time between Minnesota, New Hampshire and D.C. It could be a triangle of doom for Chip Cravaack.”

Rep. Frank Guinta (N.H.)

Guinta ousted 2006 Democratic freshman class member Rep. Carol Shea-Porter two years ago, and the liberal Democrat is back for a rematch. Wasserman said the presidential election will play a large role in determining the outcome of the races in the Granite State, where fellow GOP Rep. Charlie Bass faces another tough challenge

Rep. Francisco “Quico” Canseco (Texas)

Democrats have their sights set on reclaiming the south Texas border district that Mexican-American GOP freshman Canseco seized from veteran Democratic Rep. Ciro Rodriguez in the Latino-majority district last cycle. Both parties have pledged to spend a lot of money in a battle for the San Antonio-based district, where Canseco faces Democratic challenger State Rep. Pete Gallego Pete Pena Gallego4 Texas GOP congressional primary runoffs to watch GOP candidate scores upset win in Texas state Senate runoff Koch group launches digital ads in tight Texas House race MORE. Wasserman noted that Gallego, a farmer, survived the wave state house election in 2010. Gallego defeated Rodriguez in the 2012 Democratic primary.

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