NEW YORK -- That Indianapolis Colts-New England Patriots matchup that looked so attractive in the preseason is losing its prime-time slot.

With Indianapolis winless and Peyton Manning-less, the NFL already has decided to move the Dec. 4 game off "Sunday Night Football" under its flexible scheduling policy. The league will decide on a replacement by Nov. 22. The NFL said Tuesday that the game at New England would now be at 1 p.m. on CBS.

The critical NFC East matchup between the Philadelphia Eagles and New York Giants on Nov. 20 will remain on Sunday night on NBC. The Titans-Falcons game that day will move from 1 p.m. to 4:15 on CBS.

The NFL can use flexible scheduling starting in Week 10 to ensure meaningful matchups in high-profile time slots.