There goes the “neigh”-borhood.

A horse escaped from a Long Island farm Monday and hoofed it for nearly a mile along a busy highway during morning rush hour — before cops high-tailed it to the rescue and wrangled him, according to police and his owner.

The hot-to-trot troublemaker — a 30-year-old thoroughbred named Oppie — caused a temporary road closure on Sunrise Highway after he got spooked by a falling tree and broke free from his pen at Rockaby Farms in Brookhaven at around 7 a.m, according to Suffolk County cops and owner Erin Easop.

“I [was] thinking, please dear God, don’t let him be hit — and don’t let anybody be injured,” Easop told The Post.

When a neighbor told her the animal was on the lam near Exit 57, she raced there around 7:30 a.m., she said.

“I grabbed a halter and a bucket of food to lure him,” Easop said. “You can chase a horse down the highway but if you have nothing to grab him [with], you’re screwed!”

At least ten drivers called 911 to report that the four-legged escapee trotting west down a median separating the two-lane highway, prompting Highway Patrol officer Matthew Siesto to rush to the scene, cops said.

Several passers-by — including one who happened to have a lasso — also stopped to help catch the horse, said Siesto, who briefly shut down traffic on the road.

“We had a gentleman jump out of traffic [and] cross two lanes with a rope, trying to help,” Siesto said.

He and Easop eventually caught up to the horse and, with the help of Sheriff Patrice Silvestri cornered him and slid a halter over his face.

Easop the walked the animal back to the farm, which holds “pony parties” on Yaphank Avenue.

“It was really just lucky,” Easop said. “He’s perfectly fine, back with his brother.”