Apple removed 181 vaping apps from its online store on Friday, following the lead of federal, state and local regulators, which in recent months have cracked down on e-cigarette products.

The prohibition affects apps that help people find vape stores or flavors, allow them to control their vape pens, or gain access to games, news or social networks that promote vaping.

Apple’s vaping app ban is the second significant step the iPhone maker has taken to distance itself from e-cigarettes. The company updated its App Store rules in June to ban new vaping apps, and the move announced on Friday removed the apps it had approved before that decision. The company said it had never allowed apps that sold vaping products.

In a statement, Apple cited the rise of lung injuries and deaths linked to vaping. Health experts have recently called “the spread of these devices a public health crisis and a youth epidemic,” the company said. “We agree.”