The introduction of Opal fuel to regional and remote Indigenous communities has led to a significant decrease in petrol sniffing, according to the Federal Government.

It says two Senate inquiries have revealed a 70 per cent drop in petrol sniffing across sample communities.

There are 106 communities, roadhouses and other fuel outlets receiving the low-aromatic Opal fuel across regional and remote Australia.

A Central Australian substance abuse service says the Government must implement a mandatory rollout of Opal fuel across Australia.

The Central Australian Youth Link-Up Service's Tristan Ray says while he congratulates the government on its introduction, it is pointless unless everyone complies.

"If you put it in community A but down the road at the roadhouse near community B you can only get standard unleaded, then every car that comes through has to refuel with standard unleaded and then it comes into the community and kids syphon it out," he said.

"So to really get the benefits of Opal fuel you need it to be a regional rollout."