JERUSALEM — Thousands of Bedouins and their supporters demonstrated in various locations across Israel on Saturday against a government plan to regulate Bedouin settlement in the Negev desert, and some protesters clashed with the police.

In scenes reminiscent of the Palestinian uprisings in the West Bank, protesters hurled stones at police forces, burned tires and blocked a main road for hours near the Bedouin town of Hura in the Negev. The police used water cannons, tear gas and sound grenades to disperse the demonstrators.

Smaller protests were held in the northern cities of Haifa and Taibeh and in Israeli-annexed East Jerusalem.

Altogether, about 15 police officers were injured by stones and at least 28 protesters were arrested, said Micky Rosenfeld, a police spokesman. One officer was stabbed in the leg in Haifa, Mr. Rosenfeld said.