A crime scene has been set up after a woman was shot dead on a semi-rural property on Brisbane's south on Saturday morning.

Police had responded to reports of a shooting just after 3:00am and found the body of 40-year-old Megan Kirley when they arrived at the house on Wembley Drive, Karawatha.

Police said a 43-year-old man who lived at the property and was believed to be in a relationship with the woman was assisting them with their inquiries.

He made the triple-0 call to police.

Detective Inspector Craig Morrow could not say whether a weapon had been found.

"The scene itself is being examined forensically at the moment, the issue is that it's a large property and that will take some time," he said.

Anyone who was in the area and who may have dashcam footage has been asked to contact police.

Police have set up a crime scene at the Karawatha property. ( ABC News )