Hollywood producer-director Joss Whedon judged a group of teenage cancer survivors according to their (lack of) sexual attractiveness in order to take a shot at Republicans.

Mr. Whedon tweeted out a picture of House Speaker Paul D. Ryan meeting some teenagers and said they didn’t measure up in the attractiveness department.

“Tonight on White House Wife Hunt, Donny makes host P. Ryan give 2 more contestants the ‘Not a 10’ card,” tweeted Mr. Whedon, best known as the creator of “Buffy the Vampire Slayer,” “Firefly” and other TV shows and as the director of two “Avengers” movies.

According to Mr. Ryan, who had tweeted out the same picture, the girls were Wisconsin teenagers who “shared some powerful stories with me about their fight against childhood cancer.”

Numerous users on Twitter quickly pounced on Mr. Whedon’s remarks about the girls’ looks, calling them cruel, sexist and more.

“The epitome of misogyny right here. Take a bow, bro,: said female Twitter user “Grace Under Pressure.”

Added Franklin Harris: “Those are cancer survivors. Why do you keep insulting strong women? Is it because people keep asking you that question?”

Other folks fired back in kind, taking shots at Mr. Whedon’s own looks.

“As young cancer survivors they look a hell of a lot better than your Nicole Kidman/Ginger Baker mashup,” said Jay Caruso of the conservative Red State site.

Some Twitter users noted that Mr. Whedon has a history of demeaning remarks about women.

“He’s always ready to insult women if they cross sideways of his worldview. Ask Nicole Kidman for starters,” said Will Gregory.

In January, Mr. Whedon had responded to Ms. Kidman saying it was time to accept that Donald Trump will be the president, by posting a photo of the blond actress juxtaposed with one of a blond Barbie doll. It was accompanied with the words “Puppets for Trump: Blunderturds are Go!”

In about an hour, Mr. Whedon’s new tweet about the teenage cancer survivors had been “liked” almost 300 times.

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