Hundreds of pro-life campaigners were today met on the streets of Melbourne's CBD by a group of vocal pro-choice activists looking to disrupt a 'March for the Babies'.

With horns blaring, the pro-choice activists heckled the rally from inside the lines of campaigners who took to the streets to voice their opposition to Victorian abortion laws.

While the March for the Babies quietly progressed through the CBD, it was outside the Victorian Parliament building that police were forced to separate the groups.

Hundreds of pro-life campaigners have been met by a vocal group of pro-choice protesters on the streets of Melbourne's CBD. (9NEWS)

"I think it's so wrong that babies who are about to be born could even be killed under our state government's laws," one pro-life campaigner told 9News.

The protest march comes 10 years after the Victorian government legalised abortion in the state.

"As a result of that, over 200,000 babies have been killed in Victoria over the last decade and we want that to stop," Bernie Finn, the president of the March for the Babies said.

Pro-abortion protesters interrupted the March for the Babies outside of the Victorian Parliament building. (9NEWS)

The march came 10 years after the Victorian government first legalised abortion in the state. (9NEWS)

A number of the pro-choice campaigners who confronted the rally were dragged from the crowd by police, with one man having to be handcuffed.

Officers also located knives during searches of two other individuals nearby to the rally.

A spokesperson for the Victoria Police told 9News.com.au however that authorities believe most of those involved in the rally were well-behaved.

A number of the pro-choice campaigners who confronted the rally were dragged from the protest and moved on. (9NEWS)

Officers also located knives on two other men who were nearby to the rally. (9NEWS)

The protest comes just 40 days out from the Victorian state election, and also amid a pending High Court challenge on abortion clinic 'buffer zones'.

"I think people are quite motivated to have their voices heard and indicate they'll be voting for pro-life members of parliament or candidates," Dan Flynn, the Victorian director of the Australian Christian Lobby said.