Broncos right guard Chris Kuper will be out two to four weeks with a severely sprained left ankle.

Kuper suffered his injury in the third quarter of the Broncos’ 31-23 win Sunday at Cincinnati and had to be helped off the field.

“No fracture involved,” said Broncos coach John Fox. “There will be some rehab.”

Just because the injury doesn’t involve any broken bones doesn’t mean it’s not serious. Kuper is as tough, and unlucky, as they come. He suffered a gruesome dislocation to the same left ankle on Jan. 1 that resulted in ligament tears, fractures and major surgery.

He also suffered a fractured left ulna in training camp that required surgery.

As Kuper recovers from his latest injury, Manny Ramirez is expected to replace him at right guard. Ramirez started the first five games this season as Kuper recovered from his left arm injury

Kuper, 29, is the longest tenured member of the Broncos’ offensive line as he was a fifth-round draft pick in 2006 and has been a starter since the sixth game of the 2007 season.

There aren’t many long striders in NFL locker rooms on Monday.

After a tough, physical game Sunday in Cincinnati, many Broncos players moved through the locker room Monday in a slow shuffle.

“It doesn’t matter how old you are, you feel this game the next day,” said Broncos cornerback Champ Bailey, who spent his Sunday chasing around one of the NFL’s most dangerous receivers in the Bengals’ A.J. Green.

Fox said at his Monday news conference that other than Kuper his team got out of Cincinnati in good shape.

Mike Klis: 303-954-1055, mklis@denverpost.com or twitter.com/mikeklis