The Smiths have been through the ringer over 11 seasons, but America’s first CIA family has to endure even more in the show’s upcoming season on TBS.

The network dropped the trailer for season 12 during American Dad!‘s panel at San Diego Comic-Con on Saturday, which followed a busy animation day of The Simpsons and Family Guy (check out that panel coverage here).

The trailer — which EW has a peek at above — showed an outrageous group of vignettes from the upcoming season, which the panel moderator Jordan Blum promised would be its “funniest, weirdest, and horniest season yet.” The trailer shows off Steve’s violent attempt to be a pilot, a CIA strip tease, a fantasy musical number for Hans, and a very explicit bit of nudity for Stan.

The Comic-Con panel featured Matt Weitzman, Dee Bradley Baker, Scott Grimes, Rachael MacFarlane, and Wendy Schaal. The group teased episodes where Hayley and Jeff try to have a baby; Steve becomes possessed by Roger (‘It’s a horror movie,” said Weitzman); a Western homage episode; and a spoof of CBS’ The Amazing Race.

Guest stars for the season include Susan Sarandon, Rosie O’Donnell, Jennifer Coolidge, Walton Goggins (playing a candy-obsessed biker gang leader), Corey Stoll, Andy Richter, Wiz Khalifa, Jemaine Clement, and Alfred Molina. Plus, Rachael MacFarlane’s 6-year-old daughter will play a kindergartner in an episode called “The Portrait of Francine’s Vagina.”

The new season of American Dad! premieres in October on TBS.

Entertainment Weekly is on the scene at San Diego Comic-Con. Go inside with all our coverage, available here.