From the *Division of Clinical and Translational Research, Department of Anesthesiology, †Taylor Family Institute for Innovative Psychiatric Research, and ‡Department of Psychiatry, Washington University in St Louis, St Louis, MO.

Received September 14, 2017; accepted after revision December 12, 2017.

Reprints: Peter Nagele, MD, MSc, Division of Clinical and Translational Research, Department of Anesthesiology, Washington University School of Medicine in St Louis, 660 S. Euclid Ave, Box 8054, St Louis, MO 63110 (e-mail: nagelep@wustl.edu).

Funding/Support: This study did not receive any extramural support and was solely funded by the Departments of Anesthesiology and Psychiatry as well as the Taylor Family Institute for Innovative Psychiatric Research at Washington University School of Medicine in St Louis. Drs Conway and Nagele are supported by a grant from the National Institute of Mental Health (5R21MH108901).

Role of the funding sources: The sponsoring departments had no role in the collection, management, and interpretation of the data; or preparation, review, or approval of the manuscript.