(A) Whole specimen from sample 154 with shallow pits; (B) Partial specimen from sample 154 with deep pits; (C) Partial specimen from sample 157 displaying pits on multiple growth layers; and (D) Incipient steinkern from sample 162 displaying pits preserved as positive relief on lower half of specimen. Credit: John Warren Huntley

When seeking clues about the future effects of possible climate change, sometimes scientists look to the past. Now, a paleobiologist from the University of Missouri has found indications of a greater risk of parasitic infection due to climate change in ancient mollusk fossils. His study of clams from the Holocene Epoch (that began 11,700 years ago) indicates that current sea level rise may mimic the same conditions that led to an upsurge in parasitic trematodes, or flatworms, he found from that time. He cautions that an outbreak in human infections from a related group of parasitic worms could occur and advises that communities use the information to prepare for possible human health risks.

Trematodes are internal parasites that affect mollusks and other invertebrates inhabiting estuarine environments, which are the coastal bodies of brackish water that connect rivers and the open sea. John Huntley, assistant professor of geological sciences in the College of Arts and Science at MU, studied prehistoric clam shells collected from the Pearl River Delta in China for clues about how the clams were affected by changes caused from global warming and the resulting surge in parasites.

"Because they have soft bodies, trematodes do not leave body fossils," Huntley said. "However, infected clam shells develop oval-shaped pits where the clam grew around the parasite in order to keep it out; the prevalence of these pits and their makeup provide clues to how the clams adapted to fight trematodes. When compared to documented rises in sea level more than 9,300 years ago, we found that we currently are creating conditions for an increase in trematodes in present-day estuarine environments. This could have harmful implications for both animal and human health, including many of the world's fisheries."

Modern-day trematodes will first infest mollusks like clams and snails, which are eaten by shore birds and mammals including humans. Symptoms of infection in humans range from liver and gall bladder inflammation to chest pain, fever, and brain inflammation. The infections can be fatal. At least 56 million people globally suffer from one or more foodborne trematode infections, according to the World Health Organization.

Huntley and his team compared these findings to those from his previous study on clams found in the Adriatic Sea. Using data that includes highly detailed descriptions of climate change and radiocarbon dating Huntley noticed a rising prevalence of pits in the clam shells, indicating a higher prevalence of the parasites during times of sea level rise in both the fossils from China and Italy.

The estuarine clam Potamocorbula amurensis displaying the characteristic oval-shaped pits with raised rims induced by parasitic trematode worms. Credit: John Warren Huntley

"By comparing the results we have from the Adriatic and our new study in China, we're able to determine that it perhaps might not be a coincidence, but rather a general phenomenon," Huntley said. "While predicting the future is a difficult game, we think we can use the correspondence between the parasitic prevalence and past climate change to give us a good road map for the changes we need to make."

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More information: "A complete Holocene record of trematode-bivalve infection and implications for the response of parasitism to climate change," PNAS, www.pnas.org/content/111/51/18150.full.pdf+html Journal information: Proceedings of the National Academy of Sciences "A complete Holocene record of trematode-bivalve infection and implications for the response of parasitism to climate change,"