Improved during treatment - Remained Improved or continued to improve afterwards (>3 months)

Improved during treatment - After treatment, symptoms returned to the same degree as before

Improved during treatment - After treatment, symptoms became worse than before

Worsened during treatment - After treatment, improved to better than before treatment

Worsened during treatment - After treatment, symptoms returned to the same degree as before

Worsened during treatment - Remained worse or continued to worsen (>3 months)

No effect during - Improved after

No effect during or after

No effect during - Worsened after

Other (net positive)

Other (net negative)