Australian tennis star Nick Kyrgios has split with coach Todd Larkham less than a week out from Wimbledon.

Kyrgios withdrew from the grass-court lead-up event in Nottingham with illness earlier this week and said the pair "mutually agreed" to part ways.

"It's never an easy decision to end a coaching relationship and to do so prior to the start of a grand slam is even more difficult. But I feel that this is the right decision for me at this time," Kyrgios said on his website.

"I will work closely with my team and Tennis Australia through Wimbledon and we will regroup after the tournament in order to figure out the best plan for the future."

Larkham worked with Kyrgios for seven years during the Canberra 20-year-old's junior years and rejoined his team after Kyrgios' shock run to the last eight of Wimbledon last year, which included his upset win over Rafael Nadal.

"I've worked with Todd on and off for many years and he has helped me immensely. I am very grateful for everything Todd has taught me and helped me with, especially during the last year," Kyrgios said.

"While our working relationship has ended, Todd and I will remain friends as he has been a very important person in my life.

"For now my focus is on the 2015 Wimbledon Championships and with that in mind I will not be making any further comments on this matter."

Kyrgios' preparation for the All England Club has been less than stellar already, with his withdrawal in Nottingham coming shortly after he went down in straight sets to French Open champion Stan Wawrinka in the first round of the Queen's Club tournament.