Detroit Lions 22 Minnesota Vikings 16

Matthew Stafford threw a 28-yard touchdown pass to Golden Tate, who vaulted into the end zone in overtime to give the Detroit Lions a 22-16 victory over the Minnesota Vikings on Sunday.

After Matt Prater kicked a 58-yard field goal as time expired to force overtime, Tate finished the opening drive when he ran through arm tackles by Xavier Rhodes and Harrison Smith and leaped in for the winning score.

Stafford completed 23 of 36 passes for 219 yards, two touchdowns and an interception for the Lions (5-4), who have won four of their past five games. Tate had 11 catches for 79 yards.

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Sam Bradford completed 31 of 40 passes for 273 yards and a touchdown for the Vikings (5-3), who started the season 5-0 but have imploded since coming out of the bye. Stefon Diggs had a career-high 13 catches for 80 yards.

New York Giants 28 Philadelphia Eagles 23

Eli Manning threw for four touchdowns and New York's defense had two interceptions and three stops on fourth downs to beat Philadelphia.

The Giants (5-3) won their third straight game, holding off the Eagles (4-4 after a 3-0 start) after Manning was intercepted with less than two minutes to go.

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Two of Manning's touchdowns went to Odell Beckham Jr., with the others to Roger Lewis Jr. and Sterling Shepard.

Manning moved into ninth place in yards passing with 46,428. Manning, in his 13th NFL season, threw for 257 yards against Philadelphia. He passed Vinny Testaverde, who had 46,233 yards through the air.

Baltimore Ravens 21 Pittsburgh Steelers 14

Joe Flacco threw a 95-yard touchdown pass to Mike Wallace, and Baltimore frustrated an ineffective Ben Roethlisberger in a victory over Pittsburgh.

Baltimore (4-4) snapped a four-game losing streak and moved into a tie atop the AFC North with the Steelers (4-4), who have dropped three in a row.

Three weeks after undergoing surgery on his right knee, Roethlisberger returned well ahead of schedule. Playing for the first time since Oct. 16, the 13-year veteran looked out of sync until the fourth quarter, when he directed a 75-yard drive that got the Steelers to 21-7 with 8:38 remaining.

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Before that, Pittsburgh's offense produced only two first downs and was limited to 69 yards. The Steelers finished with 36 yards rushing, 32 by Le'Veon Bell.

Roethlisberger ran for a 4-yard score with 48 seconds left, but Chris Boswell botched the onside kick — barely knocking it off the tee — and Baltimore ran out the clock.

San Diego Chargers 43 Tennessee Titans 35

Melvin Gordon ran for a career-high 196 yards and scored the go-ahead TD on a 1-yard run, and defensive backs Dwight Lowery and Brandon Flowers scored on turnovers by Marcus Mariota to lead the Chargers over Tennessee, which still hasn't won in San Diego since 1990.

The Chargers (4-5) won two days before the team will ask voters to approve a billion-dollar subsidy for a new downtown stadium to replace aging Qualcomm Stadium. The measure was polling well short of the two-thirds supermajority needed to pass.

Gordon, who leads the NFL with 11 touchdowns, scored on a 1-yard run with 5:28 left in the third quarter to give the Chargers a 26-21 lead. He ran 32 times, and broke a 47-yard run in the closing minutes. He also caught four passes for 65 yards.

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Mariota, who led the Titans to a 21-19 lead by guiding two quick scoring drives on either side of halftime, helped the Chargers surge to a 12-point lead when he fumbled late in the third quarter. Lowery picked up the ball ran 43 yards for a touchdown and a 33-21 lead.

The Titans (4-5) have lost seven straight in San Diego since 1993, when they were the Houston Oilers. The franchise's last victory in San Diego was in 1990.

Indianapolis Colts 31 Green Bay Packers 26

Frank Gore rushed for two touchdowns, Jordan Todman had a tone-setting 99-yard return on the opening kickoff and Indianapolis held on for a win over Green Bay.

Andrew Luck shook off two interceptions in the first quarter to finish with 281 yards passing and a touchdown. The Colts, who had allowed an NFL-worst 31 sacks coming into the game, gave their quarterback decent protection.

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Indianapolis (4-5) heads into a bye week with a confidence-building victory after surviving a vintage Aaron Rodgers comeback.

His 3-yard touchdown pass to Randall Cobb with 3:29 left got Green Bay (4-4) within five, capping a 14-point spurt in four-plus minutes.

Rodgers finished 26 of 43 for 297 yards with three scores and an interception.

New Orleans Saints 41 San Francisco 49ers 23

Drew Brees threw a pair of touchdown passes to Michael Thomas and another to Mark Ingram, who also ran for a 75-yard score a week after being benched and New Orleans beat lowly San Francisco.

Ingram, replaced by Tim Hightower during last Sunday's 25-20 win against Seattle after fumbling for a second straight game, scored his second straight TD for the Saints on a career-long run to answer immediately after DuJuan Harris caught a 47-yard touchdown pass from Colin Kaepernick. Ingram's run also was the second-longest in Saints history and he wound up with 158 yards rushing as San Francisco allowed an opposing 100-yard runner for the seventh straight game.

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The Saints (4-4) have grabbed back some momentum and returned to the race in the NFC South. They won for the fourth time in five games following an 0-3 start and eighth in the past 10 regular-season meetings with San Francisco. The Niners (1-7) didn't have nearly enough to avoid their seventh straight loss since shutting out the Rams to start the season.

Carolina Panthers 13 LA Rams 10

Cam Newton persevered through five sacks to pass for 225 yards and a touchdown, and Carolina's defense shut down Los Angeles.

Greg Olsen caught a touchdown pass in the first half and Graham Gano added two fourth-quarter field goals for the Panthers (3-5), who won their second straight after a four-game skid.

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Newton's offense managed just 244 yards against the Rams' vaunted defense, but the Panthers nearly shut out Los Angeles in a defense-dominated game.

Case Keenum passed for 296 yards for the Rams (3-5), who have lost four straight after a strong start to their homecoming season. Los Angeles' scoreless streak reached 102 minutes, 12 seconds before Greg Zuerlein's 25-yard field goal with 8:01 to play.

Miami Dolphins 27 New York Jets 23

Rookie Kenyan Drake scored untouched on a 96-yard kickoff return with 5:15 left, and Miami won a seesaw battle with New York Jets.

Jay Ajayi rushed for 111 yards and helped to run out the clock after the Dolphins came from behind for the third time.

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A botched Dolphins punt led to a touchdown that put New York ahead 23-20. On the ensuing kickoff , New York's Antonio Allen was called for being offside, so the Jets had to kick again. Drake took the kickoff, found a lane and sped past the final Jet — kicker Nick Folk — into the clear.

The Dolphins (4-4) won their third game in a row, while New York (3-6) fell deeper into last place in the AFC East. The Jets hurt themselves with four personal foul penalties, two interceptions thrown by Ryan Fitzpatrick and numerous missed chances.

Dallas Cowboys 35 Cleveland Browns 10

Rookie quarterback Dak Prescott threw three touchdown passes and kept any talk for Tony Romo unnecessary, leading Dallas over winless Cleveland.

Rookie Ezekiel Elliott rushed for 92 yards and scored twice and durable tight end Jason Witten had 134 yards receiving for the Cowboys, off to their best start since 2007.

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Prescott has won seven straight starts since losing the season opener, and with the Cowboys (7-1) leading the NFC East and getting better, there's no reason for the team to accelerate Romo's return from a back injury.

The miserable Browns (0-9) dropped their franchise-record 12th straight game going back to last season and are 3-27 in their past 30. They also started 0-9 in 1975.

Kansas City Chiefs 19 Jacksonville Jaguars 14

Kansas City stuffed Jacksonville on fourth down with less than 2 minutes left deep in its own territory, preserving a victory despite finishing without five offensive starters.

Nick Foles threw for 187 yards and a first-half touchdown toss to Albert Wilson, and helped to set up four field goals by Cairo Santos, as Kansas City (6-2) won its 10th consecutive home game.

Meanwhile, the Jaguars (2-6) couldn't overcome four turnovers — including a fumble at the goal line in the fourth quarter — in their first game with quarterback coach Nathaniel Hackett directing the offense.

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Results

Baltimore Ravens 21 Pittsburgh Steelers 14

Cleveland Browns 10 Dallas Cowboys 35

Kansas City Chiefs 19 Jacksonville Jaguars 14

Miami Dolphins 27 New York Jets 23

Minnesota Vikings 16 Detroit Lions 22 (OT)

New York Giants 28 Philadelphia Eagles 23

Green Bay Packers 26 Indianapolis Colts 31

Los Angeles Rams 10 Carolina Panthers 13

San Diego Chargers 43 Tennessee Titans 35

San Francisco 49ers 23 New Orleans Saints 41

Oakland Raiders 30 Denver Broncos 20