Donald Trump's campaign manager, Kellyanne Conway, told CNBC on Tuesday the Republican presidential nominee has the right to defend himself, reacting to the billionaire businessman's late night Twitter attacks.

There's never been "such a coordinated media attack" against a candidate, Conway said on "Squawk Box," and Trump's Twitter comments are his way of fighting back.

With 34 days until the November election, Democratic nominee Hillary Clinton holds a 46 percent to 40 percent lead over Trump, according to the latest NBC News|SurveyMonkey weekly tracking poll.

While critics have called Trump's temperament into question, Clinton has a "terrible temperament," Conway said, citing Clinton's "Why aren't I 50 points ahead?" line she delivered last month before labor leaders in Las Vegas.

"That was just bizarro," Conway said.

"I can tell her why she's not 50 points ahead. She's not even at 50 percent [support] because people don't trust her, people don't like her and they don't much want her to be president," Conway said.

Truthfulness, not just temperament, should be a quality that a president should possess, the Trump campaign manager said, adding he'd also be primed to deliver on his policy promises if the House and the Senate were to remain in Republican control.

"Trump is well-positioned ... to actually enact things that all these presidential candidates, and indeed presidents from both sides of the aisle, promise and never deliver," she continued. "I think people are willing to really roll the dice here."