Firefighters at the scene of a blaze on 177th Street in Queens.

A raging fire tore through a Queens home early Sunday, killing a 7-year-old girl and her mom, and leaving her teen brothers hospitalized, according to authorities and neighbors.

To one of the family’s next-door neighbors on 117th Street in Richmond Hill, the first sign something was wrong was the terrified screams of single-mom Silvia Umana, echoing down the block at 9:30 a.m.

“I woke up to her screams. Very loud. Terror screams,” said Inderjit Singh, 22. “Then I smelled the smoke.”

Singh grabbed a few possessions and ran out in time to see a small army of smoke-eaters rushing up Atlantic Avenue to fight the flames on a day the mercury cracked triple-digits.

“The flames were very hot, coming out all the windows,” said Singh. “It was too hot here. We had to move back.”

About 100 firefighters from across 25 units battled the two-alarm blaze in shifts to stay fresh.

“Think about it: Our members respond, they wear a lot of gear, quickly overheat [and risk] heat exhaustion, which could subsequently lead to heatstroke,” said Deputy Chief Michael Ajello. “We have to rotate our personnel frequently at a fire like this.”

Eventually, the Bravest emerged from the engulfed two-story home, bearing a grim load.

“The firemen carried the children out in their arms,” said Singh. “I saw them carry out two children.”

Both Umana, 51, and her 7-year-old daughter — identified by police as Guadalupe Perez, but known to neighbors as Lupita — died in the blaze, officials said.

“Lupita, she was amazing, a very smart little kid, always smiling,” said teary neighbor Remona Elehie, 47, who often babysat the brood when Umana was at work. “A beautiful little smile.” Elehie added that Umana could often be seen around the neighborhood, accompanying Lupita for a bike ride. “The little girl is the light of her life,” said Elehie. “She’s always taking her around the block with her little bike or her little scooter.”

Umana’s teen sons, 19 and 15, were rushed to area hospitals in critical and stable condition, respectively. Next-door neighbor Hayley Santiago said that she saw emergency responders fighting to revive one of the sons after her own harrowing escape — aided by her 2-month-old kitten, Diamond.

“My cat got on my face and started meowing. It wouldn’t leave,” said Santiago, 13. “I woke up and the room was full of smoke and someone was banging on the door downstairs, very loud. I went downstairs and they said, ‘Fire! You have to get out,’” recalled Santiago. “I grabbed my cat and ran outside.”

There, she saw one of the teens being treated. “He laid down and they were doing CPR on him,” she said. The blaze, which is believed to have started on the first floor, was quashed by about 10:50 a.m.

Its cause was being probed.