The UFC on FOX 19 main card lineup continued to be ravaged today when UFC announced Lyoto Machida was out of Saturday’s co-main event showdown with Dan Henderson in Tampa, Fla.

Machida (22-7 MMA, 14-7 UFC) admitted to taking a banned substance and was pulled from the middleweight bout with Henderson (31-14 MMA, 8-8 UFC), marking the third time the card has lost a scheduled main or co-main event fight.

It’s unknown exactly which substance Machida took and what the repercussions for his actions will be beyond losing the fight with Henderson. However, that didn’t stop plenty of people from criticizing the former UFC champ.

Check below for the top Twitter reactions to Machida’s removal from his UFC on FOX 19 fight with Henderson.

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UFC has released a statement on Lyoto Machida and changes to this weekend's card: https://t.co/Q7l37z3Yaa — Dave Sholler (@Sholler_UFC) April 13, 2016

New FOX Main Card: Glover-Rashad, Rose-Tecia, Khabib-Horcher, Swanson-Dias — Dave Sholler (@Sholler_UFC) April 13, 2016

I feel like the UFC's statement writer must be developing a callus at this point. — Michael Carroll (@MJCflipdascript) April 13, 2016

The Machida piss jokes are already getting annoying. — Seán Sheehan (@SeanSheehanBA) April 13, 2016

Machida pulled from card. Damn! Card to a hit. There's still some good fights on #UFCTampa but I'd been looking forward to that matchup. — Gorgeous George (@MMAjunkieGeorge) April 13, 2016

Mousasi calling Machida a cheater back in February. @mousasi_mma pic.twitter.com/MdmuHJUpJF — caposa (@GrabakaHitman) April 13, 2016

Hey @mousasi_mma you appear to have been right! — Tom Lawlor (@FilthyTomLawlor) April 13, 2016

@danhendo was ready for machida, it does prove he had a good game plan though- step 1: cheat step 2: refer back to step 1 — Sam Alvey (@smilensam) April 13, 2016

would watch. RT @shaunalshatti: Screw it. Cowboy vs. Hendo. Who says no? — Daniel Rubenstein (@dannyrube) April 13, 2016

Another one bites the dust… Keep knocking em off @usantidoping. — James Krause (@TheJamesKrause) April 13, 2016

Three UFC fighters (including two former champions) in trouble with USADA in less than a week. — Guilherme Cruz (@guicruzzz) April 13, 2016

Body count keeps rising with PEDs. How desperate must you be to continue to use PED drugs in spite of the program? Hendo hit it P.O.S. — Chris Wade (@CWadeMMA) April 13, 2016

If you fight and beat someone up and fail for PED it should be criminal let alone suspensions. Dan is in his mid 40s, smh. Gross — Chris Wade (@CWadeMMA) April 13, 2016

Seriously – ALL FIGHTERS – download the WADA app. Here's what pops up if you search "DHEA." Clearly banned. pic.twitter.com/sbsGhICTkB — John Morgan (@MMAjunkieJohn) April 13, 2016

Man, @ufc @ufconfox @fs1 all these guy eating bad meat, drinking pee popping for PEDs We should do The Natural… https://t.co/p6meo73I2N — Roy Nelson (@roynelsonmma) April 13, 2016

Lyoto Machida vs. Dan Henderson fight cancellation marks the 12th main or co-main event change to the UFC calendar so far in 2016. — Mike Bohn (@MikeBohnMMA) April 13, 2016

Machida fails drug test. In the words of Nate Diaz "I'm not surprised motherfuckers!" — michael (@bisping) April 13, 2016

Middle weights with steroid use. Anderson, machida, vitor, hendo, Yoel,who am I missing? Almost the entire top ten. — michael (@bisping) April 13, 2016

https://twitter.com/TimKennedyMMA/status/720408484953501696

I will fly and fight @danhendo right now. My mouth piece is in my pocket. I don't need anything else. — Tim Kennedy (@TimKennedyMMA) April 14, 2016

USADA strikes again. When will these guys grow some balls… naturally. — Luke Rockhold (@LukeRockhold) April 13, 2016

Lyoto Machida admits use of banned substance, fight with Dan Henderson scrapped at UFC on FOX 19 https://t.co/qgTCaKlPMP — MMAjunkie (@MMAjunkie) April 13, 2016

For more on UFC on FOX 19, check out the UFC Rumors section of the site.