no Oprah is not the antichrist because of these reasons. First it is because Christ was a man so the antichrist has to be a man. The antichrist also needs to perform miracles to make others believe that he is not the anticrist. The Antichrist must have great power in authority. He will also have great power from the devil but he will claim it to be god's. The Antichrist must also be related to Israel. Obviously, he's already here... Barack Hussien Obama is all of those. He's a male, he's the president of the United States of America, he's an atheist who said he "appreciates" prayers & yet he says "we need to be above religon", & he was actually born in Kenya, which is south of Jerusalem. In the Bible, it is said that the antichrist will also be the "King of the South".