Donald Trump's economics speech at the Detroit Economic Club was interrupted thirteen separate times by protesters, mostly women, who yelled slogans into a cavernous convention center ballroom and drew mostly indifference from the Republican nominee for president.

As Trump wound his way through a stinging indictment of the Obama administration and Democratic nominee Hillary Clinton's economic proposals, one agitator after another screamed in anger.

One boomed about 'victimized' females. another blared: 'You have to answer to women, Mr. Trump!'

The comic relief came from the lone male protester, who ranted: 'Tiny hands! All you've got is tiny hands!'

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UNFLAPPABLE: Donald Trump stuck to his economic message during a speech Monday to the Detroit Economic Club

ONE AFTER ANOTHER: Thirteen different women erupted in screams, one at a time, as Trump spoke to an audience of 2,000

'PEOPLE'S CAMPAIGN': A left-wing Michigan group took credit for organizing the protest

'TINY HANDS!' The lone male protester screamed an insult at Trump before security yanked him from his seat

The audience responded with standing ovations and cries of 'We love you!'

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Trump mostly shook his head silently, and plowed ahead through his prepared remarks without giving television audiences a hint at what was transpiring.

Eventually, though, a few quips snuck into his delivery after a black woman screamed on her way out: 'I did it for you!'

'This is what happens when you go from 35 people to more than 2,000, I guess,' Trump said, a swipe at Clinton's smaller crowds on the campaign trail.

'It's all very well planned out,' he said as police dragged one kicking protester out of the Cobo Center in downtown Detroit.

'I will say the Bernie Sanders people have far more energy and spirit,' he said of another.

As that activist was ejected, a woman hear her in the audience yelled, 'Get a job!'

By sheer coincidence, the next line in Trump's speech was: 'We must have law and order.'

A left-wing group called Michigan People's Campaign claimed credit for organizing the protest, and said its members each purchased tickets to the speech – which cost about $100 each according to audience members.

The organization said in a press release that it was protesting against Trump's 'stance on sexual harassment' and his policies' likely impact on automotive jobs.

OPEN DOOR POLICY: The fifth demonstrator to interrupt Trump found herself ejected

OUT YOU GO: Trump's security chief Keith Schiller, left, and a mixture of Secret Service and Detroit police officers, hauled protester after protester out of the Cobo Center

STANDING O FOR IVANKA: Trump name-checked his elder daughter as someone who has advised him on jobs, and the Detroit crowd erupted in appreciation

GOP TICKET: Indiana Gov. Mike Pence, Trump's running mate, said Trump is 'a dreamer, he's a builder, he's a driver and he's a man who speaks his mind'

Trump said his message was the need to start 'a conversation about how to make America great again for everyone, especially – and I say especially – for those who have the very least.'

But most of his largest applause lines were slaps at Clinton, including some that linked Democratic politicians to Detroit's crumbling, crime-ridden inner city.

'The city of Detroit is the living, breathing example of my opponent's failed economic agenda,' Trump said. 'Every policy that has failed this city, and so many others, is a policy supported by Hillary Clinton.'

'She supports the high taxes and radical regulation that forced jobs out of your community, and the crime policies have made you far, far less safe, and the immigration policies that have strained local budgets, and the trade deals like NAFTA, signed by her husband, that have shipped your jobs to Mexico and other countries.'

'And she supports the education policies that deny your students choice, freedom and opportunity,' he continued, to wild applause.

'She is the candidate of the past. Ours is the campaign of the future.'

HILLARY-BASHING: Trump clobbered Hillary Clinton as a voice from the past and promoted his economic vision as a plan for the future

'OUT OF IDEAS': Trump clobbered his opponent, saying that 'if you were a foreign power looking to weaken America, you couldn't do better than Hillary Clinton's economic agenda'

'This is a city controlled by Democratic politicians at every level. And unless we change policies, we will not change results,' Trump said 'One hundred per cent.'

'Our opposition ... has long ago run out of ideas,' Trump said, promising an expansion of his economic proposals on his website.

'All Hillary Clinton has to offer is more of the same. More taxes, more regulations, more bureaucrats, more restrictions on american energy and on American production. More of that!'

'If you were a foreign power looking to weaken America, you couldn't do better than Hillary Clinton's economic agenda. Nothing would make our foreign adversaries happier than for our country to tax and regulate our companies and our jobs right out of existence.'

After Trump left the podium, a female emcee said: 'I want to apologize to all of you and to Mr. Trump for the interruptions. This is not what the Detroit Economic Club is all about.'

Indiana Gov. Mike Pence, Trump's running mate, introduced the billionaire candidate.

'We've become best friends. He seems like somebody I've known all my life,' said Pence.