The matchup on “Monday Night Football” between the Cleveland Browns and New York Jets contains way more subplots than you might expect in a Week 2 game between winless teams with a combined playoff drought of 26 seasons (17 for the Browns, nine for the Jets).

The Browns’ record is 0-1 after the unofficial winners of the offseason were blown out by the Tennessee Titans, 43-13, as Baker Mayfield threw three interceptions. The Jets are 0-1 after blowing a 16-point lead at home against the Buffalo Bills.

During the week, Jets QB Sam Darnold was diagnosed with mononucleosis, putting the second-year passer out of action for multiple weeks and thrusting Trevor Siemian into the starting role. Browns star wide receiver Odell Beckham Jr., when he wasn’t generating headlines with his insistence on wearing a six-figure watch on the field, sparked a feud with Jets defensive coordinator Gregg Williams. Keep an eye on how physical Jets defenders get with the explosive Beckham.

Here’s what to know about Monday Night Football and how to watch:

When is the Browns-Jets game?

Kickoff between the Browns and Jets is scheduled for 8:15 p.m. ET.

Where is the game?

The Jets are hosting the Browns at MetLife Stadium in East Rutherford, New Jersey.

Who is on the Jets injury report?

Quarterback Sam Darnold (illness) is out after being diagnosed with mono. Starting linebacker C.J. Mosley (groin) and rookie defensive lineman Quinnen Williams (ankle) were ruled out for this game. Wide receiver Quincy Enunwa (neck) was ruled out for the season.

Wide receiver Demaryius Thomas, acquired this week from the New England Patriots, is questionable after not practicing all week.

Running back Le’Veon Bell (shoulder) is expected to play after an MRI exam this week came back clean.

What TV channel is Browns-Jets on and is there a live stream?

“Monday Night Football” will air on television on ESPN.

You can stream through WatchESPN by entering your cable-subscriber information.

Or you can live stream through ESPN+. New subscriptions for ESPN+, which include access to exclusive college football, UFC and soccer coverage as well as the reboot of the network’s “NFL PrimeTime,” cost $4.99 per month or $49.99 per year.

What are the odds for Browns-Jets?

The Browns are favored by 6.5 points over the Jets. The Over/Under is 45.