Three-time Paralympic gold medallist Carol Cooke is appealing for the return of two of her gold medals after they were stolen from her car this morning.

One of cyclist Carol Cooke's gold medals, stolen from her car. ( ABC News: Guy Stayner )

Cooke's car was broken into at the Victorian Institute of Sport at Albert Park while she went for a training ride.

She said the thief stole her Paralympic team backpack which had both of the gold medals inside.

"The police, when I told them, they said what's the value, and I said they're invaluable," Cooke said.

"You can't put a value on them because they mean nothing to anybody else. They mean everything to me."

Cooke is a cyclist with multiple sclerosis (MS) who won gold in London and two golds in Rio.

She said the medals were a crucial part of her regular presentations to school groups.

"I'm not the type of person that puts them away and doesn't let anybody see what they're like," Cooke said.

"I think it's really important to share them with everybody. It's devastating."

Cooke said a Paralympics toy mascot was also in the stolen backpack.

She urged anyone who found the medals to return them to a police station.