Passengers have described their miraculous and terrifying escape from a plane crash in Mexico.

Dozens of people are injured, two critically, after the Aeromexico aircraft crashed shortly after taking off from the airport.

Jackeline Flores was on board and says the plane crashed amidst heavy rain.

Passengers miraculously walking away from the wreckage of the Aeromexico plane alive, and on foot. Picture: AAP (Nine)

103 people were on board the plane, 85 were injured and 37 of those were hospitalized. Two are critical. Picture: AAP (nine)

An Aeromexico airliner has crashed shortly after taking off from an airport in Mexico with at least 80 people on board. (Nine)

She and her daughter escaped from a hole in the fuselage as the aircraft filled up with smoke and flames. "I am very blessed and grateful to god," she said.

Another passenger told 9NEWS, "the smoke started, then the fire, kids were screaming. We managed to get out of that hole...I was afraid to jump but we did it. We did it without thinking."

Many passengers were able to leave the plane on foot. One man is sure the plane was hit by lightning. However authorities say it was a "gust of wind", during the storm.

The cause of the crash has not been determined. (Nine)

No fatalities have been reported immediately following the crash. (Nine)

The accident occurred near the General Guadalupe Victoria International Airport in Durango.

The plane, flying under flight number AM2431, was travelling to Mexico City.

The governor of Mexico's Durango state says 85 people were injured, and 37 of those were hospitalised. The pilot was the most severely hurt, but he is in a stable condition.

Aeromexico is the flag carrier airline of Mexico and hasn't had a fatality in over 30 years. (Nine)

(9news)

The crash involved an Embraer 190 plane, with 103 people on board including two infants and four crew.

The head of Mexico's Transport Department said earlier that "the plane fell upon takeoff". It has now been confirmed that the plane's left wing hit the ground, knocking off two engines, before it came to a halt 300 metres from the runway.

The civil defense office of Durango state says the plane came down in a field near the airport for the state capital, also named Durango.

Aeromexico is the flag carrier airline of Mexico and hasn't had a fatality in over 30 years. (Nine)

"We deeply regret this accident and the families of all those affected are in our thoughts," Aeromexico said in a statement.

"We're focused on dealing with the situation and are doing everything necessary to assist the families of our passengers and crew during this difficult time."

The Embraer E190 is known for its strong safety record. The plane involved in the crash is believed to be 10 years old.

Aeromexico Embraer E190. Picture: File (Nine)

The web site Planespotters.net says the Brazilian-made medium-range jet had seen service with two other airlines before joining the Aeromexico fleet.

Durango is more than 885 kilometres northwest of Mexico City.

Aeromexico is the flag carrier airline of Mexico and hasn't had a fatality in over 30 years.