A naked man rampaged up and down the aisles on an Alaska Airlines flight before being detained and locked in the toilet by crew.

Former Alaska state lawmaker Johnny Ellis tweeted about the incident from inside the plane headed from Seattle to Anchorage, Alaska.

He said the nude passenger ran from the front of the plane to the back, yelling and waving, before the aircraft took off.

A naked man ran up and down the aisles yelling on an Alaska Airlines flight from Seattle to Anchorage, Alaska (file image)

Alaska Airlines spokeswoman Bobbie Egan said in a statement Monday night that Alaska Airlines flight 107 from Seattle landed without incident in Anchorage.

Egan says shortly before the descent into Anchorage a disruptive male passenger was detained. She says he was removed by law enforcement after the plane parked at the gate and was then transported to a local hospital.

She didn't say whether the man was clothed or what led to the incident.

Mr Ellis tweeted: 'WOW. On my flight from Seattle to Anchorage, a completely naked man ran from the front of the plane to the back, yelling and waving.

Former Alaska state lawmaker Johnny Ellis tweeted about the incident from inside the plane

He speculated the passenger was either on drugs or alcohol - or having a psychotic breakdown

'Two big guys, maybe one Air Marshall, tackled him and locked him in the bathroom. Some fear and distress at passengers.

'I waited for a wheelchair and was next to last off the plane.

'Police boarded to take naked guy away. We thought [he was on] drugs not booze.

'May have been psychotic break since some said guy who chased and tackled him [said he] was actually his father. Flight attendants were debriefing.

'The Captain was extra nice to passengers.