Sherlock Holmes you may not be, but hand–foot syndrome, known by the medical term palmar-plantar erythrodysesthesia, is something to watch out for.

Hand-foot syndrome may occur when cancer treatment affects the growth of skin cells or blood vessels in the hands and feet. Redness, swelling, loss of fingerprints, and pain have been reported.

Cancer drugs cited to cause this effect include:

although it can happen with others. If you develop hand-foot syndrome, talk to your doctor; there are ways to manage it and prevent it from worsening.