The third-deadliest fire in California state history has taken lives, homes, businesses and burned some of the nation's most popular vineyards.

Over 8,000 firefighters are battling the 21 wildfires that have ravaged 191,437 acres. At least 3,500 homes and businesses have been destroyed and an estimated 25,000 people forced to evacuate.

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"There are a number of significant wineries that haven't reported in yet, or are still not out of the woods as of this afternoon," said Emily Pennington, managing editor Wine & Spirits Daily.

Napa and Sonoma counties are home to around 900 wineries (of 4,600 statewide) and represent 13% of the state's output. And the state itself supplies 85% of the nation's wine production, making it the fourth-largest producer of wines after Italy, France and Spain.

As flames continue to rage in wine country, here are a few updates on some of the state's wineries, compiled with help from Pennington:

Chimney Rock Winery, Napa: The winery and vineyards were unharmed, according to the winery's Facebook page. While some staff members were displaced, they are all safe.

Darioush Winery, Napa: The winery building and staff are safe, according to the winery's Facebook page. The property did lose half of its landscaping, according The New York Times.

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Domaine Carneros, Napa: Closed for business until at least Oct. 16, according to the winery's Facebook page. A San Francisco Chronicle report did say Domaine Carneros is "perfectly intact."

Francis Ford Coppola Winery, Geyserville in Sonoma County: The winery is closed, but was unaffected, according to its Facebook page. It has a small crew working to maintain some harvest operations.

Gundlach Bundschu, Sonoma: The winery, one of the oldest family-owned wineries in the state, is currently closed, because of active fires in the area. "Some vineyards were torched," according to a Press Democrat report.

Paradise Ridge Winery, Santa Rosa: The winery was lost in the fire, but estate vineyards survived, the winery said on its website.

Pine Ridge Vineyards, Napa: While staff is safe, some lost their homes, according to the vineyard's website. Pine Ridge has been without power, but the estate vineyards are unharmed.

Rutherford Hill, Rutherford: The winery and vineyards were unharmed, according to the winery's Facebook page. While some staff members were displaced, they are all safe.

Shafer Vineyards, Napa: While the winery is closed, the building and vineyards escaped damage, according to its Facebook page.

Signorello Winery, Napa: The winery buildings "burned to rubble, but the vineyards are in "good shape," the winery posted on Facebook. All employees are safe.

Treasury Wine Estates' Chateau St. Jean, Sonoma Valley: The property suffered minor damage to an out-building, with cosmetic and landscaping damage, according to its Facebook page.

Treasury Wine Estates' Stags' Leap Winery, Napa: Employees, buildings and vineyards are safe, according to the winery's Facebook page. The winery is currently closed because of evacuations.

Follow Ashley May on Twitter: @AshleyMayTweets

Marco della Cava and Elizabeth Weise contributed to this report.