Police are investigating a break-in at Rob Gronkowski’s Foxborough, Mass., home, which resulted in the theft of “multiple safes and possible guns taken,” according to The Boston Globe.

On Tuesday, Foxborough Police Chief William D. Baker released a statement regarding the burglary, which is said to have occurred while Gronkowski, 28, was in Minneapolis for Super Bowl LII, where the Eagles defeated the Patriots on Sunday, 41-33.

“There were items stolen,” Baker said. “We’re not going to release the nature of the items stolen.”

Though Baker did not get into specifics, audio on the Foxborough police dispatch advises officers to “speak with the homeowner there who reports while he was away on his trip his house was broken into, multiple safes and possible guns taken.”

Authorities arrived at Gronkowski’s home around 6 p.m., which is located a short distance from Gillette Stadium. The Patriots returned to Massachusetts on Monday afternoon.

“I think it’s a tough combination,” Baker said. “You know, to have suffered this unfortunate loss and then to get home and be a victim of this kind of crime.”

With the investigation said to be “very active and dynamic,” Baker stated there will be no further comment until the case is resolved.

Following New England’s crushing loss, Gronkowski revealed he is contemplating retirement.

Gronkowski was at least the fourth celebrity athlete to be victimized by home burglars while playing sports in the past year — joining a slew of Hollywood stars whose homes also were hit, typically after they posted details on social media about being away.

Tennis ace Venus Williams had $400,000 worth of valuables, including several Hermès bags and personal photographs, stolen from her Palm Beach Gardens, Fla., home between Sept. 1 and Sept. 5 while she was playing in the US Open in New York.

Los Angeles Dodgers outfielder Yasiel Puig’s Encino, Calif., house was broken into and $150,000 in property was taken just one hour after his team lost Game 7 of the World Series on Nov. 1.

Los Angeles Laker Nick Young’s pad was burglarized and bandits reportedly stole $500,000 in money and jewelry while he was at the NBA All-Stars weekend in New Orleans last February.

Singers and actors — including Nicki Minaj, Emmy Rossum, Alanis Morrisette and Hilary Duff — also had their homes burglarized in the past 12 months, reportedly while they were traveling.

Experts say celebrity-home crime appears to be on the uptick for one obvious reason: Thieves can get updates on stars’ whereabouts by trolling them online and checking blogs.

“It used to be [burglars] would go through a street of a well-to-do neighborhood and look in the bay windows,’’ Bill Stanton, a founder of the security group Qverity, told The Post.

“Now, they go through their cellphones, and say, ‘Who isn’t home?’ ”