“My conclusion about Mr. Trump’s unsuitability for office is based on his disregard for the precept of treating others with respect, an idea that should transcend politics,” Collins writes. "Instead, he opts to mock the vulnerable and inflame prejudices by attacking ethnic and religious minorities.”

The Maine senator does not say in the op-ed who she plans to vote for in November. But she says she does not support Hillary Clinton, writing, "As we have seen with the dissatisfaction with both major-party nominees — neither of whom I support — these passions are real and the public will demand action."

In an interview with the New Yorker magazine published in June, Collins said it was possible that she would vote Clinton. “I worked very well with Hillary when she was my colleague in the Senate and when she was secretary of State,” she said at the time. But she added that "it is unlikely that I would choose to vote for the Democratic candidate."

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Collins becomes the latest in a small but growing group of Republican senators who have said they will not vote for Trump. Sen. Ben Sasse of Nebraska has vocally opposed the mogul for months. Sen. Lindsey O. Graham of South Carolina told CNN in May that he did not intend vote for Trump or Clinton.

Others, like Sen. Jeff Flake of Arizona, have criticized Trump sharply, but stopped short of definitively saying they will not vote for him.

Fifty national security officials who served under Republican presidents signed a letter Monday saying Trump is “not qualified” to be president.

Collins writes that Trump’s criticism of Khizr Khan, who spoke out against the mogul at the Democratic National Convention and whose son Capt. Humayun Khan was killed in Iraq, was an especially bad moment for the GOP nominee.

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“Rather than honoring their sacrifice and recognizing their pain, Mr. Trump disparaged the religion of the family of an American hero. And once again, he proved incapable of apologizing, of saying he was wrong,” writes Collins.

Collins says she hoped Trump would change once the general election campaign started.