Rep. Seth Moulton Seth MoultonOvernight Defense: Nearly 500 former national security officials formally back Biden | 40 groups call on House panel to investigate Pentagon's use of coronavirus funds The Hill's Morning Report - Presented by Facebook - Markey defeats Kennedy; Trump lauds America's enforcers in Wisconsin Moulton fends off primary challenges in Massachusetts MORE (D-Mass.) called Rep.-elect Alexandria Ocasio-Cortez Alexandria Ocasio-CortezOn The Money: Anxious Democrats push for vote on COVID-19 aid | Pelosi, Mnuchin ready to restart talks | Weekly jobless claims increase | Senate treads close to shutdown deadline McCarthy says there will be a peaceful transition if Biden wins Anxious Democrats amp up pressure for vote on COVID-19 aid MORE's (D-N.Y.) tweet defending House Minority Leader Nancy Pelosi Nancy PelosiPelosi slams Trump executive order on pre-existing conditions: It 'isn't worth the paper it's signed on' On The Money: Anxious Democrats push for vote on COVID-19 aid | Pelosi, Mnuchin ready to restart talks | Weekly jobless claims increase | Senate treads close to shutdown deadline Trump signs largely symbolic pre-existing conditions order amid lawsuit MORE's (D-Calif.) Speaker campaign as "offensive" during an interview with Boston Public Radio on Friday.

Ocasio-Cortez tweeted earlier in November that challenges to Pelosi becoming Speaker were "coming from her right, in an apparent effort to make the party even more conservative and bent toward corporate interests."

Moulton told BPR that her characterization of Pelosi's opposition was “offensive” not only to him, but to legislators like Linda Sánchez (D-Calif.) who also called for a change in leadership among House Democrats.

“It’s offensive because [Sánchez] is in the progressive caucus, she is not to the right of Nancy Pelosi, and it’s also offensive because she’s a woman,” Moulton said.

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Moulton, who is very involved in the Pelosi opposition movement within the party, explained that a new generation of leaders is needed.

“We need to make room for a new generation of leaders," Moulton said. "This election was a call for change from the American people, and we have an extraordinary freshman class that includes a lot of young people, LGBT candidates and an extraordinary number of women and veterans."

He also said that he doesn't have personal animosity against Pelosi, but that she has "a stranglehold on the caucus right now that people recognize that if they come out against her now, that she’ll turn all her allies against whoever steps up in a very vindictive way and it’ll be very hard to win an election.”

Democrats overwhelmingly nominated Pelosi for Speaker on a secret-ballot vote earlier this week. Pelosi will now face a Jan. 3 floor vote in her bid to become Speaker in the 116th Congress.

A representative for Ocasio-Cortez did not immediately respond to The Hill's request for comment.