A woman has been taken to hospital after an overhead sign fell and crushed her car on Melbourne’s Tullamarine Freeway yesterday.

Emergency services were called to the freeway near Essendon Airport after the freak accident occurred about 5.30pm.

A 53-year-old woman suffered minor neck injuries and was taken to the Royal Melbourne Hospital in a stable condition, Ambulance Victoria told 9News.

A woman has been taken to hospital after the overhead sign fell onto a car below. (9News)

Authorities are investigating how this freak accident occurred. (9News)

The woman was kept overnight for observation but is expected to be released today.

Images taken in the moments after the incident show a black car crushed by the sign, with its windscreen shattered and glass strewn across the road.

Acting Sargent Jason Lane said police had received dash cam footage but urged any other motorists with video of the incident to please come forward.

The inbound exit from the freeway to Bulla Road and Bell Street is now re-opened to motorists.

A woman has been taken to hospital after the overhead sign fell onto a car below. (9News)

Major Roads Project Victoria is investigating into how this freak accident occurred.