Enough is enough with the Lady Gaga and Madonna comparisons.

In a recent interview with with Zane Lowe for Beats 1 Radio, the "Perfect Illusion" singer once again had to set the record straight on what seems to be a recurring interview theme.

"Madonna and I are very different," said Gaga. "I wouldn't make that comparison at all. I don't mean to disrespect Madonna...she's a nice lady, and she's had a fantastic, huge career. She's the biggest pop star of all time...But I play a lot of instruments. I write all my own music. I spend hours and hours a day in the studio. I'm a producer. I'm a writer. What I do is different."