Vladimir Putin has referred to "the territories which now belong to Ukraine" in ominous comments during his annual phone-in.

The Russian President made several remarks about Ukraine, recent anti-government protests and his country's relations with the United States, during A Direct Line With Putin.

"I hope at some time this period in the life and history of Ukraine and the Ukrainian people will come to an end," ​Mr Putin said.

Mr Putin used the question and answer session to talk to voters about key issues ahead of next year's presidential election, which he is expected to contest.

Anti-Putin protests: Russian police arrest hundreds as thousands rally against Kremlin corruption

He went on to say how much he values the views of Ukranians who remember the "common history" uniting Russia and Ukraine. "We grasp it and we value it highly, believe me."

Russia annexed Ukraine's Crimean Peninsula in 2014 and is supporting pro-Russia insurgents in eastern Ukraine, leading Western nations to place sanctions on Moscow.

"If it wasn't for Crimea, other problems, they would have invented something else to deter Russia," he said.

During the tightly choreographed marathon TV appearance, Mr Putin gave a rare glimpse into his private life, saying he has two grandchildren whose privacy he wants to respect, and even spoke to a man whose wife had given birth moments ago.

Trump and Putin passionately kiss in street mural Show all 14 1 /14 Trump and Putin passionately kiss in street mural Trump and Putin passionately kiss in street mural A lesbian couple kisses in front of mural depicting Russian President Vladimir Putin and Republican presidential candidate Donald Trump, on the walls of a barbecue bar 'Keule Ruke' on May 19, 2016 in Vilnius, Lithuania. Barcroft Media/Getty Trump and Putin passionately kiss in street mural A lesbian couple kisses in front of mural depicting Russian President Vladimir Putin and Republican presidential candidate Donald Trump, on the walls of a barbecue bar 'Keule Ruke' on May 19, 2016 in Vilnius, Lithuania. Barcroft Media/Getty Trump and Putin passionately kiss in street mural VILNIUS, LITHUANIA - NOVEMBER 23: A woman walks past a mural showing U.S. President-elect Donald Trump (R) blowing marijuana smoke into the mouth of Russian President Vladimir Putin on the wall of a bar-b-que restaurant on November 23, 2016 in Vilnius, Lithuania. Many people in the three Baltic nations of Lithuania, Latvia and Estonia are concerned that Russia, because Trump has expressed both admiration for Putin and doubt over defending NATO member states, will be emboldened to intervene militarily in the Baltics. Sean Gallup/Getty Trump and Putin passionately kiss in street mural A woman walks past a mural on a restaurant wall depicting US Presidential hopeful Donald Trump and Russian President Vladimir Putin greeting each other with a kiss in the Lithuanian capital Vilnius on May 13, 2016. Kestutis Girnius, associate professor of the Institute of International Relations and Political Science in Vilnius university, told AFP -This graffiti expresses the fear of some Lithuanians that Donald Trump is likely to kowtow to Vladimir Putin and be indifferent to Lithuanias security concerns. Trump has notoriously stated that Putin is a strong leader, and that NATO is obsolete and expensive. Petras Malukas/AFP/Getty Images Trump and Putin passionately kiss in street mural AP Trump and Putin passionately kiss in street mural A child walks past a graffiti depicting Russian President Vladimir Putin, left, and Republican presidential candidate Donald Trump, on the walls of a bar in the old town in Vilnius, Lithuania, Saturday, May 14, 2016. (AP Photo/Mindaugas Kulbis) AP Trump and Putin passionately kiss in street mural People walk past a mural on a restaurant wall depicting US Presidential hopeful Donald Trump and Russian President Vladimir Putin greeting each other with a kiss in the Lithuanian capital Vilnius on May 13, 2016. Kestutis Girnius, associate professor of the Institute of International Relations and Political Science in Vilnius university, told AFP -This graffiti expresses the fear of some Lithuanians that Donald Trump is likely to kowtow to Vladimir Putin and be indifferent to Lithuanias security concerns. Trump has notoriously stated that Putin is a strong leader, and that NATO is obsolete and expensive. Petras Malukas/AFP/Getty Images Trump and Putin passionately kiss in street mural A man photographs a mural on a restaurant wall depicting US Presidential hopeful Donald Trump and Russian President Vladimir Putin greeting each other with a kiss in the Lithuanian capital Vilnius on May 13, 2016. Kestutis Girnius, associate professor of the Institute of International Relations and Political Science in Vilnius university, told AFP -This graffiti expresses the fear of some Lithuanians that Donald Trump is likely to kowtow to Vladimir Putin and be indifferent to Lithuanias security concerns. Trump has notoriously stated that Putin is a strong leader, and that NATO is obsolete and expensive. Petras Malukas/AFP/Getty Images Trump and Putin passionately kiss in street mural AP Trump and Putin passionately kiss in street mural A young woman walks past a mural showing U.S. President-elect Donald Trump (R) blowing marijuana smoke into the mouth of Russian President Vladimir Putin with the slogan "make everything great again," in reference to Trump's campaign slogan of "Make America Great Again," on the wall of a bar-b-que restaurant on November 23, 2016 in Vilnius, Lithuania. Many people in the three Baltic nations of Lithuania, Latvia and Estonia are concerned that Russia, because Trump has expressed both admiration for Putin and doubt over defending NATO member states, will be emboldened to intervene militarily in the Baltics. Sean Gallup/Getty Trump and Putin passionately kiss in street mural A morning commuter stops to look at a mural on a restaurant wall depicting US Presidential hopeful Donald Trump and Russian President Vladimir Putin greeting each other with a kiss in the Lithuanian capital Vilnius on May 13, 2016. Kestutis Girnius, associate professor of the Institute of International Relations and Political Science in Vilnius university, told AFP -This graffiti expresses the fear of some Lithuanians that Donald Trump is likely to kowtow to Vladimir Putin and be indifferent to Lithuanias security concerns. Trump has notoriously stated that Putin is a strong leader, and that NATO is obsolete and expensive. Petras Malukas/AFP/Getty Images Trump and Putin passionately kiss in street mural Restaurant owner Dominykas Ceckauskas pose next to a mural on the wall of his establishment depicting US Presidential hopeful Donald Trump and Russian President Vladimir Putin greeting each other with a kiss in the Lithuanian capital Vilnius on May 13, 2016. Kestutis Girnius, associate professor of the Institute of International Relations and Political Science in Vilnius university, told AFP -This graffiti expresses the fear of some Lithuanians that Donald Trump is likely to kowtow to Vladimir Putin and be indifferent to Lithuanias security concerns. Trump has notoriously stated that Putin is a strong leader, and that NATO is obsolete and expensive. / AFP / Petras Malukas (Photo credit should read PETRAS MALUKAS/AFP/Getty Images) Petras Malukas/AFP/Getty Images Trump and Putin passionately kiss in street mural A passerby photographs a mural showing U.S. President-elect Donald Trump (R) blowing marijuana smoke into the mouth of Russian President Vladimir Putin on the wall of a bar-b-que restaurant on November 23, 2016 in Vilnius, Lithuania. Many people in the three Baltic nations of Lithuania, Latvia and Estonia are concerned that Russia, because Trump has expressed both admiration for Putin and doubt over defending NATO member states, will be emboldened to intervene militarily in the Baltics. Sean Gallup/Getty Trump and Putin passionately kiss in street mural Getty

He described Ukranian nationalists as "swastika-brandishing loonies" and added the fathers of Ukranian nationalism believed the country should be a federal state.

"We have many friends in Ukraine," he said, before going on to say the Ukranian nationalists "all believed Ukraine should be independent but it should also be a federal state."

He added that "over-centralisation... would lead to domestic conflicts in Ukraine. This is what we have been witnessing.

"By the way, some of the defenders of the Ukrainian independence and the Ukrainian nationalism did not see Crimea as part of Ukraine."

He said construction of a bridge to connect mainland Russia with Crimea is on schedule "and even slightly ahead of it". It is meant to be operational by the end of next year.

Mr Putin also joked that Russia would offer asylum to former FBI director James Comey (Getty Images) (Getty)

During the four-hour show, Mr Putin accused his opponents of "abusing" and exploiting problems in Russia rather than offering a solution.

He said that while "street protests always emerge as part of democratic procedures," they were "not being done to improve the situation in the country."

He also said Russia's campaign in Syria had allowed the military to test its state-of-the art weapons in real combat.

The experience allowed engineers to polish weapons designs and has given a "new quality" to the Russian military, he said.

Putin offers political asylum to Comey

Mr Putin also joked that Russia would offer asylum to former FBI director James Comey, who was fired by Donald Trump.

He said it was "very strange" the FBI official had leaked details of conversations with the US President and compared his actions to those of Edward Snowden.

The Russian President said his country was "ready for a constructive dialogue" with the US.

Mr Putin said Moscow and Washington could cooperate in efforts to prevent the proliferation of mass destruction weapons, including the North Korean nuclear and missile problem.

He said the two countries could also cooperate in dealing with global poverty and efforts to prevent climate change.

"As far as the flashpoints are concerned... there are positive examples of our cooperation. Syrian problem, Mid-Eastern problem on the whole... There are other flashpoints and we are very hopeful for the United States' constructive role in the resolution of the Ukrainian crisis... We are ready for a constructive dialogue."