Chilean can reach a PL feat previously achieved by only four Arsenal players, plus more pre-match stats

Should he find the back of the net against Leicester City on Wednesday evening, Arsenal's Alexis Sanchez will follow in the footsteps of Thierry Henry, Ian Wright, Robin van Persie and Emmanuel Adebayor.

While Sanchez chases his 20th of the Premier League season, Tottenham Hotspur's Harry Kane will be looking to increase the deadliest goal ratio in Premier League London derby history.

Look ahead to the five midweek matches below.

Tuesday 25 April

Southampton's 3-1 win last season is their only victory in their last seven PL trips to Chelsea (W1 D3 L3)

Wednesday 26 April

Alexis Sanchez needs one goal to become the fifth Arsenal player to reach 20+ goals in a PL campaign

Sunderland are unbeaten in their last three Premier League trips to Middlesbrough (W1 D2)

With 18 goals in 24 matches, Harry Kane has the best goals-per-match ratio (0.75) in PL London derbies

Thursday 27 April

Man Utd will equal their longest unbeaten top-flight run within a single season if they avoid defeat (24 matches in 2010/11)

See: Matchweek 34: What we have learned