Federal authorities in Manhattan busted six suspected MS-13 gangbangers on racketeering, weapons and drug charges, according to an indictment unsealed Wednesday.

The suspects — with gang nicknames such as “Smiley,” “Tricky” and “Enigma” — allegedly conspired together to sell methamphetamine in New York City as part of their membership in the vicious Latin American street gang, prosecutors for the Southern District of New York said.

Suspects Amilcar Romero, Jaime Santana, Jose Garcia and Alexander Rivera were hit with narcotics-distribution and racketeering charges, prosecutors said. Cristian Guerrero-Melgares and Gustavo Lleevano-Rivera were charged with narcotics conspiracy, authorities said.

Federal investigators worked with the NYPD to make the busts, which were lauded by law-enforcement officials as arrests that will keep crime down in the city.

“By precisely targeting the relatively small percentage of individuals responsible for committing much of the violence in New York, we are making the safest large city in America even safer,” NYPD Commissioner O’Neill said in a statement.

Garcia, Guerrero-Melvares and Rivera appeared at a court hearing Wednesday where they were presented with the charges against them.