TAMPA — Neil Walker is set to make his Yankees debut on Friday night against the Astros, with the plan to play the newly signed veteran at first base — for one game, at least.

“We’ll try to get him games at second and third,” Aaron Boone said of Walker, who seems likely to be the Yankees’ regular second baseman once he shakes off the rust from not having signed with a team until this week.

Tyler Wade continues to give Boone and the Yankees something to consider, though, as he got on base twice and made a pair of outstanding plays at second in Thursday’s 9-5 win over the Pirates at George M. Steinbrenner Field.

“It was another one of those days where he opens your eyes,” Boone said of Wade. “Just the dynamic he brings.”

Wade showed range both up the middle and to his left against Pittsburgh and also impressed Boone with his toughness at the plate after hard-throwing lefty Felipe Rivero came up and in on him in the fourth and he managed to draw a walk.

“That’s a big-time at-bat,” Boone said. “He’s a better player than I thought. Just his athleticism and instincts.”

Walker will be tested after playing in an intrasquad minor league game on Wednesday following just a dozen at-bats at the camp run by the MLB Players Association in Bradenton, Fla.

“The good thing when I checked in with him this morning was how good he felt,” Boone said. “It’s a tribute to the shape he came in.”

And he wants to see more of both infielders.

“I’m going to weigh it all,” Boone said of how he wants to use them. “I look at it as we have two really good players that can impact our club in different ways.”