NEW YORK—Federal prosecutors and the FBI have sought to interview Prince Andrew about Jeffrey Epstein, but he has provided “zero co-operation,” the U.S. attorney in Manhattan said Monday.

Geoffrey S. Berman, the U.S. attorney, revealed Andrew’s lack of co-operation in response to a reporter’s question during a news conference outside Epstein’s Manhattan mansion about victims of sex trafficking.

Andrew, following a disastrous TV interview over his ties to Epstein, said in a statement late last year that he was willing to help law-enforcement agencies in their investigations into the disgraced financier and his associates.

“Of course, I am willing to help any appropriate law-enforcement agency with their investigations, if required,” his statement said.

Epstein hanged himself last summer at a jail in Manhattan, where he was awaiting trial on federal sex trafficking and conspiracy charges. Prosecutors had accused him of sexually exploiting dozens of women and girls in New York and Florida.

Shortly after Epstein’s death, Berman issued a statement vowing to continue the investigation into his co-conspirators.

The case brought renewed scrutiny to Epstein’s relationships with prominent figures in politics, academic and business — including Andrew, the second son of Queen Elizabeth II, who is also known as the Duke of York.

The prince has said he met Epstein in 1999.

One of Epstein’s accusers, Virginia Roberts Giuffre, has said that Epstein trafficked her to Andrew when she was 17, an accusation the prince denied.

In 2011, a photograph was published that Giuffre said was taken in 2001. The snapshot showed Andrew standing alongside her in a London apartment with his arm wrapped around her bare waist with Epstein’s former girlfriend, Ghislaine Maxwell, standing in the background.

Maxwell, a British socialite who was a friend of Andrew, has been accused in civil lawsuits of recruiting girls and young women for Epstein to sexually abuse.

A few months after Epstein’s death, Andrew gave a televised interview with the BBC about his relationship with Epstein that caused an uproar in Britain and prompted him to step back from public duties. During the interview, he said he had “no recollection” of meeting Giuffre.

During the interview, Andrew also said he would have to consult with his lawyers before testifying under oath about his ties to Epstein.