David Arquette's wife is pregnant.

The 45-year-old actor and his spouse Christina announced on Instagram on Wednesday that they're expecting their second child together and are thrilled that it's another little boy.

Taking to his Instagram account, the 'Scream' star - who also has 12-year-old daughter Coco with his ex-wife Courteney Cox - uploaded a sweet video of their two-year-old son Charlie holding a picture of the baby scan.

Scroll down for video

Happy news: David Arquette and his wife Christina, pictured last year, are expecting another child together

Instagram announcement: The actor shared the news by posting a video of his son Charlie holding a sonogram

He accompanied the adorable clip with the caption: 'So incredibly blessed and honored that my wife @christinaarquette is pregnant with a baby boy! Thank you Christina and humbled gratitude to G-D for this tremendous gift! Charlie and Coco are so excited and I am over the moon!!!'

Charlie is certainly very excited with the little boy holding on to the ultrasound photo proudly and even trying to speak the baby.

'Hello baby,' the toddler says in the video.

Too cute: Charlie is certainly very excited with the little boy holding on to the ultrasound photo proudly and even trying to speak the baby

'Over the moon': The 45-year-old accompanied the adorable clip with the caption

While Christina keeps telling him to speak to his brother, the two-year-old struggles with the word.

No doubt he will soon get used to the idea that he is a big brother.

The news couldn't have come at a better time as David was left heartbroken last month after his sibling Alexis, who had been battling with HIV for 29 years, died aged just 47.

'Hi baby!' In the video, Christina keeps telling him to speak to his brother but the two-year-old struggles with the word

Coming soon: The tot has some time to learn how to say and be a big brother

He said at the time: 'Thank you all for your love and kind words about Alexis. My hero for eternity.'

David - who has battled with alcohol addiction - and Christina first started dating in 2011 but their romance was very much on and off until they fell pregnant with Charlie in 2013.

They got engaged just three months after the now-toddler was born and they tied the knot just under a year later on April 12, 2015 in an intimate ceremony in Los Angeles, California.

Baby makes three: The 'Scream' star also has 12-year-old daughter Coco with his ex-wife Courteney Cox (pictured August)

Meanwhile, David recently admitted that becoming a father has changed him drastically and he's learnt from his mistakes.

He said: 'Since Charlie has come into my life, I love Coco more than ever,' he adds. 'Having a son has brought back memories and made me realise how much I miss enjoying her as a baby.

'I am older and more mature and can return to raising a baby more aware of the wonderful daily experiences.'