The wife of Democratic presidential candidate Bernie Sanders Bernie SandersKenosha will be a good bellwether in 2020 Biden's fiscal program: What is the likely market impact? McConnell accuses Democrats of sowing division by 'downplaying progress' on election security MORE says front-runner Hillary Clinton Hillary Diane Rodham ClintonWhat Senate Republicans have said about election-year Supreme Court vacancies Bipartisan praise pours in after Ginsburg's death Trump carries on with rally, unaware of Ginsburg's death MORE must tap a progressive running mate if she wants to unify the party when the long primary season is over.

“We definitely want Secretary Clinton to pick a progressive,” Jane Sanders said on MSNBC. "The agenda has changed."

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The democratic socialist's wife says his campaign has "transformed the Democratic Party over the course of this year," and, if Clinton secures the nomination, she'd need a liberal vice president choice "we can really stand behind."

Jane Sanders said, however, that the Vermont senator remains the best hope of averting a Donald Trump Donald John TrumpObama calls on Senate not to fill Ginsburg's vacancy until after election Planned Parenthood: 'The fate of our rights' depends on Ginsburg replacement Progressive group to spend M in ad campaign on Supreme Court vacancy MORE presidency.

“The most important thing is that [presumptive GOP presidential nominee] Donald Trump has to be defeated,” she said. "He doesn’t stand for what American values stand for."

Bernie Sanders is campaigning hard in California ahead of the Golden State's huge primary vote on June 7. His bid suffered a blow when Gov. Jerry Brown (D) backed Clinton on Tuesday, but Jane Sanders dismissed the endorsement, saying the former secretary of State often racks up establishment support.

“We’re used to having governors and senators and congressmen vote for, or endorse, Secretary Clinton,” she said. "We’ve just accepted that. I think there is a lot of pressure on office holders to support Secretary Clinton. That’s fine; that’s totally fine."

Clinton holds a substantial lead nationwide, boasting 2,312 delegates to Sanders’s 1,545. At least 2,382 are needed for avoiding a contested Democratic National Convention in July.

Still, Jane Sanders said, "I think Bernie is the better person to go against Donald Trump. All the polls keep on showing that.”