A 25-year-old man has been charged following an alleged hit-and-run collision which left a cyclist with life-threatening injuries in West Melbourne.

Paramedics were called to the intersection of Dryburgh Street and Dynon Road in West Melbourne on Thursday night to find the cyclist, 18-year-old Ben Tyrrell from Cloverlea in Gippsland, with serious head injuries.

A man from Footscray presented at a police station just after 5:00pm.

He was later charged with failing to report the collision to police, failing to stop and failing to render assistance.

Ben Tyrrell remains in a coma in hospital. ( Supplied: Victoria Police )

He was bailed by police to appear in the Melbourne Magistrates Court on November 22.

Mr Tyrrell remains in a serious condition in the Royal Melbourne Hospital.

His parents made an emotional appeal for the driver to turn themselves in to police.

Julie and Kevin Tyrrell said their son had just finished celebrating completing a flooring job in Melbourne when he was hit.