Owsley Stanley, the prodigiously gifted applied chemist to the stars, who made LSD in quantity for the Grateful Dead, the Beatles, Jimi Hendrix, Ken Kesey and other avatars of the psychedelic ’60s, died on Saturday in a car accident in Australia. He was 76 and lived in the bush near Cairns, in the Australian state of Queensland.

His car swerved off a highway and down an embankment before hitting trees near Mareeba, a town in Queensland, The Associated Press reported. Mr. Stanley’s wife, Sheilah, was injured in the accident.

Mr. Stanley, the Dead’s former financial backer, pharmaceutical supplier and sound engineer, was in recent decades a reclusive, almost mythically enigmatic figure. He moved to Australia in the 1980s, as he explained in his rare interviews, so he might survive what he believed to be a coming Ice Age that would annihilate the Northern Hemisphere.

Once renowned as an artisan of acid, Mr. Stanley turned out LSD said to be purer and finer than any other. He was also among the first individuals (in many accounts, the very first) to mass-produce the drug; its resulting wide availability provided the chemical underpinnings of an era of love, music, grooviness and much else. Conservatively tallied, Mr. Stanley’s career output was more than a million doses, in some estimates more than five million.