Michael David Smith at ProFootballTalk.com thinks the Seahawks win by six, 20-14, "The Cardinals are a much better team than they showed early this season, but the Seahawks' defense is outstanding, and I think Carson Palmer is going to struggle on Sunday night."

Mike Florio at ProFootballTalk.com has Seattle winning by seven, 30-23, "The Cardinals have won two in a row against one-win teams. They still have a long way to go to become what they were last year. The Seahawks likewise aren't quite what they were last year, but they're closer than Arizona is."

Peter Schrager at FOXSports.com predicts a big game for Arizona running back David Johnson and a 24-23 Cardinals win, "Arizona has won two straight, and I think the Cardinals keep it going Sunday night. Seattle has owned Arizona in that Bird's Nest the past three years, that's for sure. The Seahawks have outscored Arizona by a combined 105-34 the past three times the teams played in Glendale. But this has David Johnson National TV Coming Out Party written all over it. Give me the Cards in the game of the week."

Vinnie Iyer at Sporting News takes the Seahawks to win 27-20, "There's something a little off with Carson Palmer and Arizona's passing game, something that Richard Sherman and Seattle's defense, out to correct the bad lapses they had vs. Atlanta, can exploit. Palmer and Russell Wilson come in a little banged up, and they can't expect to get the boosts they've gotten from their running backs against these defenses. Doug Baldwin and Larry Fitzgerald are a wash, so it comes down to the other weapons who can get open for big pass plays. This is the kind of game for which the Seahawks got Jimmy Graham."

Chris Burke at SI.com predicts a 20-16 Seahawks win, "The Seahawks are 17–17 all-time against Arizona, but they've won their last two trips to the desert by a combined 71–12. Granted, Ryan Lindley was the Cards' starter for one of those games, and Carson Palmer sat early last year in Week 17 because Arizona had its playoff positioning locked up. Palmer's presence, in theory, levels the field, but his team's offense has shifted away from him and into the arms of RB David Johnson. Seattle's excellent run defense—not to mention its speed through the linebacking corps—could shift the onus back onto Palmer. Arizona's own defense perked up against the Jets on Monday. Houston/Tampa Bay castoff D.J. Swearinger has provided yet another athletic, fast-flying body to team with Deone Bucannon and Tyrann Mathieu. The question is if it that will be enough against Russell Wilson. Seattle's QB is on pace for a career high in passing yards this season."

Danny O'Neil at 710Sports.com picks in the Seahawks' favor, 23-13, "The Seahawks have won the past three road games against the Cardinals by a combined score of 105-34 while Arizona has won two of the past three games in Seattle. The strange thing in this matchup is that Seattle is the one whose rushing game is struggling, the Seahawks ranked 25th in yards per carry and 30th in yards per carry."

Four of the eight analysts at CBSSports.com think the Seahawks will win.

Eight of nine experts at ESPN.com pick a Seattle victory.