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Its users have described crossing into another world and seeing “machine elves,” aliens or cartoon cats. One woman reported being swarmed by apparently alive Slinky toys.

Now scientists at a prestigious U.S. university are launching a study of some of the stranger hallucinogenic effects of the drug Dimethyltryptamine, or DMT, termed the “spirit molecule” by another researcher.

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Investigators from Johns Hopkins University in Baltimore, Md., are asking volunteers to complete an online survey if they have “had encounters with seemingly autonomous beings or entities after taking DMT.”

The Hopkins team is headed by Roland Griffiths, a behavioural biologist with a history of studying psychedelic substances that produce “mystical-type and near-death experiences.”

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They call their latest project important research that could be personally worthwhile to the subjects, with the goal to better characterize the DMT experience.