A depleted Adelaide United will need to change half their side for a daunting away fixture against A-League frontrunners Brisbane Roar on Saturday.

Frontman Bruce Djite (groin), attacking midfielder Cirio (hamstring) and winger Fabio Ferreira (groin) are expected to miss the match, while defender Osama Malik is suspended.

Suspended: Osama Malik. Credit:Getty Images

And Jake Barker-Daish, who scored in Adelaide's 2-2 draw with Sydney FC on Friday night, is unavailable due to national under-22 duties.

Djite and Cirio were on Monday awaiting scan results to determine the extent of their injuries. They were forced off within 10 minutes of each other against the Sky Blues.