There are nearly 2 million people living with limb loss in the United States (1).

Among those living with limb loss, the main causes are vascular disease (54%) – including diabetes and peripheral arterial disease – trauma (45%) and cancer (less than 2%) (1).

Approximately 185,000 amputations occur in the United States each year (2).

In 2009, hospital costs associated with amputation totaled more than $8.3 billion (3)

African‐Americans are up to four times more likely to have an amputation than white Americans (4)

Nearly half of the individuals who have an amputation due to vascular disease will die within 5 years. This is higher than the five year mortality rates for breast cancer, colon cancer, and prostate cancer (5)

Of persons with diabetes who have a lower extremity amputation, up to 55% will require amputation of the second leg within 2‐3 years (6)