I feel that could be a great and interesting storyline that the "Web Warriors" series could look into.



In the Ultimate universe (1610) Gwen first died but came back then shortly afterwards Peter himself dies and Gwen responded while grieving "I'm cursed" (believing she somehow caused Peter to die by her existence).



Spider-Gwen (a Spider-Gwen from either Earth-65 or some other Earth) exist and is apart of the Web Warriors team and many times Gwen meets a new Spider hero the spider responds with shock and sadness seeing that version of Gwen due to what happened to their's (to a point it's starting to annoy Gwen to a certain point) or they go to a new Earth and discover the that Peter or other person who was Spider-Man has died yet Gwen lives (and some where both are dead.



With the concept of the "Web of Destiny" and the concept of magic maybe 1610 Gwen could have a point. Something has affected the Web and thus causing these tragedies to happen to all Spider-heroes or their love ones bind to them til the thread/web is cut and it has something to do with a Multiverse Gwen and a Multiverse Peter at the center of it all.



That not just informing why some bad things happen but afterwards the villain is beaten and a ray of hope has begun for new worlds to be discovered where the possibility of both Peter and Gwen could be able to live and be heroes while the other exists.