Calls for an 18-month trial of a safe injecting room for drug addicts have been rejected by the Andrews government, despite its admission that drug and alcohol abuse is out of control in some communities.

Reason Party MP Fiona Patten proposed an 18-month trial of a medically supervised injecting room near Victoria Street in North Richmond, the epicentre of Melbourne's heroin crisis.

Thirty-four people died from drug overdoses in the area last year and hundreds more needed treatment.

But a parliamentary inquiry report by a group of cross-party MPs failed to take a definitive stance on the trial, with MPs split along party lines.