A shocking new report published in the National Enquirer is claiming Charlie Sheen has been diagnosed with HIV.

The publication said it has completed an “exhaustive” 18-month long investigation and can finally uncover how “television’s one-time highest paid star potentially spread the devastating virus to dozens of unsuspecting women.”

“Sheen, 50, has already begun a regimen of medication meant to counteract the effects of the disease,” sources told the magazine.

“Charlie had sex with multiple partner since learning his HIV status without informing them of his potentially deadly HIV infection,” one source told the Enquirer.

The whole story about Sheen, who has bragged that he’s slept with over 5,000 women, will be published November 18.

While the National Enquirer is the only publication reporting this news, the actor is scheduled to make a “revealing personal announcement” to Matt Lauer on the “Today” show Tuesday. Many are speculating it could be his diagnosis.

A request for comment from Sheen’s rep was not immediately returned. (VIDEO: Charlie Sheen: ‘We Deserve More From Our President’)