A Sydney man has faced court accused of the shooting murder of his 23-year-old nephew Saif Jouda in Sydney's west.

Mr Jouda was shot in the head several times when he answered a knock at the front door of his home at Horsley Park on April 23.

Police arrested and charged his uncle Abdul Dwikat, 47, from Granville on Friday at Yennora in Sydney's west.

Mr Jouda from the Palestinian territories, moved to Sydney with plans to marry just months before he was killed.

Police said that six months of detailed work led to the arrest and described the incident as brutal and calculated.

Dwikat appeared at the Parramatta Bail Court today via video link and is expected to face a bail application next Friday at Fairfield Local Court.