HELENA, Mont. — The first large-scale hunt for grizzly bears in 43 years in the Lower 48 states is set to take place this September. The Wyoming Fish and Game Commission voted unanimously Wednesday to allow hunters to shoot as many as 22 grizzlies east of Yellowstone National Park.

Two weeks ago, the state of Idaho announced the first grizzly season since 1974, just before the Yellowstone grizzly population was listed as an endangered species. Idaho, though, will allow just one grizzly bear to be killed.

Montana has decided to forgo a grizzly bear season this year.

The hunt has been carefully planned to protect the species, officials say. “Wyoming is committed to ensuring a recovered population,” said Scott Talbott, director of the state’s Game and Fish Department.

Hunting season on grizzlies in Wyoming comes a year after the federal Fish and Wildlife Service lifted Endangered Species Act protection for the population of bears in the Yellowstone area. It found that their numbers have grown from fewer than 150 in 1975 to more than 700 bears in and around the park, and are recovered.