Three-hundred-seventy-seven people per day.

That’s the staggering average daily death toll the Big Apple has absorbed for the last 42 days since the coronavirus pandemic claimed its first reported victim inside the five boroughs on March 14.

The disease’s staggering toll means Gotham lost more residents to the awful disease per day than homicides have claimed annually in recent years.

And Friday, the count continued to grow as the city’s Health Department reported the disease claimed another 437 lives — and now stands at 15,848.

That includes 10,746 people who died after testing positive for the virus and 5,102 who had the disease’s tell-tale symptoms but died before they could be checked for COVID-19.

Officials again cautioned that the new tally figure likely includes deaths from several previous days because of the time it takes to process paperwork.

Unlike the city, the state health officials do not include probable deaths in daily tallies, despite promises to do so.

Meanwhile, the number of coronavirus cases in New York City continued to grow, albeit more slowly than it did at the height of the crisis — rising from 141,754 on Thursday to 146,139 on Friday.

Queens has the most COVID-19 cases at 45,313, followed by Brooklyn at 38,727, the Bronx at 32,862, Manhattan at 18,252 and Staten Island at 10,917.

Despite climbing deaths and cases figures, other key coronavirus indicators declined Friday: The number of patients in intensive care units and hospitalizations for suspected coronavirus are trending downward, Mayor Bill de Blasio said during his daily press briefing.

“Just plain good day,” de Blasio said as he applauded New Yorkers for the progress. “Congratulations because you did this. Everyone out there — you did this [with] social distancing, shelter-in-place.”