US stocks ended the day down nearly 200 points, pulled down by concerns over Deutsche Bank.

The Dow Jones industrial average closed down 1% at 18,143. Deutsche Bank stock fell 6.6% following a report that hedge funds had withdrawn cash from the troubled lender.

Nasdaq also fell, down 49.39 points to 5,269, despite shares in both NXP Semiconductors and Qualcomm soaring on speculation of a takeover.

The S&P 500 lost 20.24 points to finish at 2,151.