The study was conducted by South-Korean scientists from UNISET (Ulsan National Institute of Science and Technology), as part of a partnership with other US institutes researching aging (John Hopkins University, Groningen Medical University and the University of California.)

Senescent cells that appear in joints after a lesion occurred favor the development of post-traumatic osteoarthritis. The researchers proved that by eliminating senescent cells, it is possible to stunt the development of degenerative diseases of the joints and to get rid of the associated pain. In addition, eliminating senescent cells in the joints also created a favorable environment for new cartilage and tissue regeneration.

The results confirm the theory according to which elimination of excess senescent cells in a specific organ helps to maintain its function over time.

This study on UBX0101 paves the way for new therapies targeting senescent cells, to fight aging-related diseases and prolong human lifespan.