A popular winery on Victoria's Mornington Peninsula has gone up in flames, resulting in the loss of hundreds of thousands of dollars of damage and lost product.

The fire broke out at venue Ten Minutes by Tractor just after 4pm today, sending smoke billowing into the air.

Customers and staff were evacuated from the property.

A fire has ravaged popular Mornington winery Ten Minutes By Tractor. (Facebook / Grahame Tiplady)

The fire broke out just after 4pm. (Facebook / Grahame Tiplady)

There is no word what sparked the blaze. (Facebook / Grahame Tiplady)

Images from the 9NEWS helicopter show part of the winery completely gutted.

A staff member was treated by paramedics after suffering minor burns trying to evacuate everyone from the building.

A staff member has suffered minor burns trying to evacuate people from the burning building. (9NEWS)

Part of the property has been completely gutted. (9NEWS)