Senator Nick Xenophon has promised to shake up the South Australian parliament by launching a new party to run candidates at next year's state election.

The party has been named SA Best, in what is expected to be the start of a wider re-branding for the senator's federal party the Nick Xenophon Team (NXT), and will run with the slogan "Forget the rest, vote SA Best".

Senator Xenophon said the party would give South Australians a strong alternative choice from the two major parties.

"It's about a voice from the political centre, grassroots, common sense, and we are out to give the major parties — the two tired, old parties — a run for their money," he said.

"I think it's going to be the most interesting and exciting state election that we have had in a very long time."

The party is calling for potential candidates to lodge expressions of interest but some candidates are expected to be announced in May.

Xenophon builds on federal election momentum

At last year's federal election, the NXT won three South Australian senate seats with Stirling Griff and Syke Kakoschke-Moore joining Senator Xenophon on the crossbench.

NXT's Rebekha Sharkie took the Adelaide Hills seat of Mayo from Liberal frontbencher Jamie Briggs for a seat in the House of Representatives.

Senator Xenophon said he would know how many seats the party would run candidates in by the middle of the year.

"At least in the Adelaide Hills, in the northern suburbs and the southern suburbs of Adelaide there is strong support for people having that alternative voice," he said.

"Given how we went at the last federal election it means that we've got a fighting chance of getting it across the line in a number of seats."

Senator Xenophon said the party aimed to make politicians "truly accountable" and to have leaders with "real life skills".

The party is expected to detail its vision for the state over the coming weeks.