This first quarterly update of the Zika Strategic Response Plan (July 2016 to December 2017) includes the latest information on Zika across the globe as well as the resources needed to prepare for and respond to Zika virus and potential neurological complications. As we continue to learn more about Zika, these updates aim to guide coordination and collaboration among WHO and its partners so that countries’ preparedness and response capacities are supported to the fullest extent possible.