As your kitty nears the end of her life, there's little you can do but make her comfortable. One key way is to reduce the stress in her environment. For example, keep a favorite blanket or one of your old T-shirts nearby, so that she has something familiar and comforting when you can't be around. Brushing her coat every day helps too, because she may not be able to groom herself with much ease anymore. And hard as it may be, if your cat insists on having some solitude, go ahead and give it to her. If that's what gives her peace, then show your love by granting it.