(CNN) "This outbreak appears to be over," the US Centers for Disease Control and Prevention said Wednesday of the E. coli outbreak linked to romaine lettuce from some regions of Northern and Central California.

In all, 62 people in 16 states became sick as a result of the outbreak. Twenty-five of them were hospitalized.

Illnesses began in early October; the most recent illness was reported to have begun with symptoms on December 4.

The CDC says the E. coli outbreak tied to romaine lettuce is over.

However, the US Food and Drug Administration is continuing to investigate how the outbreak occurred and the farms involved.

The outbreak was first announced two days before Thanksgiving with a stark warning for consumers to stay away from all romaine lettuce while an investigation looked for the source of the bacteria.

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