Midfield has been a big issue for Jose Mourinho ever since he took on the Tottenham job back in November.

With the head coach pretty much deciding on who he starts in defence and attack, there has been an awful lot of rotating in the middle of the park.

Eric Dier was immediately moved back into his holding role but has not been seen there for a few games, while Harry Winks and Tanguy Ndombele have been in and out of the team following the managerial change.

Moussa Sissoko has been the one to nail down a regular place under Mourinho but Spurs are now going to have to do without him for the next three months after he underwent surgery on his knee on Tuesday.

Alasdair Gold on the impact of Sissoko's long term injury

It's obviously a major blow for the club and it leaves Mourinho facing a big decision over who starts in midfield against Liverpool as there is no exact date on when Ndombele will return after limping off at Southampton on New Year's Day with a hip injury.

Oliver Skipp and Victor Wanyama are both options to play in midfield, while Giovani Lo Celso, Christian Eriksen and Dele Alli can all play deeper if needed.

Skipp seems the natural one to step up in Sissoko's absence given Wanyama's knee troubles over the past couple of seasons, but there is also someone else Mourinho could turn to if he looks to add to his midfield.

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A total of seven players left the club on loan at the start of the season to pick up valuable experience of playing in the first team.

However, it's not gone to plan for Jack Clarke, Cameron Carter-Vickers, Kazaiah Sterling and Anthony Georgiou as the quartet have since returned to north London after finding playing time limited due to injury and other reasons.

One player still out on loan at Championship side Queens Park Rangers is midfielder Luke Amos.

The 22-year-old was handed his Premier League debut at the start of the 2018/19 season by Mauricio Pochettino at Newcastle United as he came on for the final few minutes after making an impression on the club's pre-season tour of the United States.

Tragedy struck one month later as he ruptured the anterior cruciate ligament in his left knee as he captained the U23 side in a Premier League 2 clash against Blackburn Rovers.

The injury ruled him out for the rest of the campaign and it meant that he couldn't add to his solitary league appearance for the Lilywhites.

Amos is now getting regular playing time in the Championship with QPR and has so far played in 19 games in all competitions for the west London outfit this season, scoring two goals in the process.

Returning from injury against Hull City in October after a month on the sidelines, Rangers boss Mark Warburton hailed the youngster and claimed he would have a "big impact" at the club over the course of the season.

"That was his first first-team game for the past four or five weeks. He had that injury, the medical team has looked after him, [and] so he’s back," said the manager, as reported by West London Sport .

"He’s a talented lad, a really talented player, and we have to look after all our players, but it’s great to see him back on the pitch. There’s no doubt between now and May he will have a big impact for us."

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A player with more experience of playing first-team football than Skipp having previously spent time on loan at Southend United and Stevenage, the talented midfielder does remain an option for the club to bring back if they deem it necessary.

However, Mourinho and Spurs may believe it's beneficial for the player to remain at the Kiyan Prince Foundation Stadium and get more minutes under his belt before he returns to the club in the summer and looks to make a real impression in the team two years after his first-team bow.