Red Sox broadcast icon Jerry Remy, who has suffered from lung cancer recurrences for the past 10 years, said his latest diagnosis has been the most difficult to accept.

“It’s been hard because we really didn’t expect it,’’ Remy told the Boston Globe on Wednesday, a day after NESN announced his sixth diagnosis. “It hit me hard. It’s like … this is never going to stop. We didn’t anticipate this result. …

“I kind of expected a good result because the last checkup had been good and that was just a little more than six weeks ago. But the area was starting to reshape as a tumor, and the biopsy came back positive.”

The 65-year-old discovered a spot on his lung a week and a half ago after taking a CT scan during the regular checkup he goes to every six weeks. He took July 30 off for a scheduled biopsy. Remy’s last recurrence was as recent as last season.

Remy said he has put his faith in his medical team at Massachusetts General Hospital, and he plans to participate in “all the tests” and “huddle with his doctors” to map out his next steps to recovery. It is unknown when Remy will return to the broadcast booth.

“We’re all kind of shocked. This caught me by surprise. Now it’s up to me … the tests, the treatments,” said Remy, who was first diagnosed with lung cancer in November 2008. “I’m not indestructible. Nobody is. But I do hope I influence other people.”

The former Red Sox second baseman said if his fight with cancer can inspire “one person, one family” to have the strength to continue battling, then unveiling his pain to the public would be worth it.

“I have two choices: quit or fight. I’m going to fight,” Remy told the Boston Herald. “Because I reach so many people through television, if I can give them some hope, then that’s what I’m going to do.”

Red Sox fans rallied around the Massachusetts native after he posted on Twitter that he would “never quit” trying to overcome cancer.

“Thank you for all of your support,” he wrote. “This has hit me hard but I have never quit and will not now. I have complete trust in my team at Mass General. Bring it home Sox!!!”

Remy said he hopes the red-hot Sox make a run to the World Series and win it, per the Boston Herald. Remy didn’t deny the possibility of being with the team come October.

Remy has been calling Red Sox games for the past three decades but has reduced his workload due to his illness. After ending his baseball career in 1985, Remy joined the NESN booth in 1988.

“There’s no way to predict now if there’s a return or if there’s not a return,’’ Remy said. “I just can’t do that now because we haven’t gathered all the information. We haven’t decided on the course of treatment. There’s no way of knowing what’s down the line for me.”

Remy said he told NESN president and CEO Sean McGrail of his current situation Monday night.

“NESN and the Red Sox have been really, really supportive of everything that I’ve been going through,’’ Remy said. “All of the support I’ve been getting over the last 48 hours from everyone has been remarkable. It doesn’t surprise me. It’s happened to me before, and it’s not an unusual situation to be in for me, but I appreciate it.”

On Tuesday night, Red Sox manager Alex Cora said the team is praying for Remy.

“Obviously, thoughts and prayers for Jerry. I just texted him. God is in control, and he’ll be back with us sooner rather than later,” Cora said before the Red Sox’s game with Toronto. “We’re going to miss him for now. We know that he’s going to be fine, and he’s going to be back with us.”