ROBYN BECK/AFP/Getty Images

"The whole cast, including Christina, is down to do little bits in it," Faustino said, adding, "The idea would be a pilot for a spinoff. That's all I can say right now. It involves me and few other people."

The show, which ran for 11 seasons on Fox until 1997, centered around the very dysfunctional Bundy family with Ed O'Neill as shoe salesman Al and Katey Sagal as his wife Peggy.

"All of us have said we would all be there for [Faustino]," said Applegate, who played the Bundys' daughter Kelly.

Asked what she thinks her character would be up to these day, Applegate said. "Kelly Bundy probably has like 10 kids. I'm sure of it."

Married With Grandchildren, anyone?

We've got lots more from the Vacation premiere tonight on E! News at 7 p.m. and 11 p.m.