Collingwood are uncertain whether big-bodied onballer Brayden Sier will be available for selection to replace midfielder Taylor Adams against Carlton next Saturday after Adams was injured in the win over Port Adelaide on Friday night.

Sier, who is yet to play a senior game this season after playing the final 12 games in 2018 including the grand final, has missed the past two weeks with what the Magpies have described as a toe injury.

With Collingwood's bye in the VFL this week forcing Sier to miss another week, the Magpies are more likely to consider Travis Varcoe or James Aish for the Blues and reshuffle their midfield to replace Adams, who suffered an adductor strain.

The injury, which he has been battling over the past few weeks, is likely to keep Adams sidelined for at least the next few weeks with forgotten midfielder Rupert Wills also a possible recall.

Collingwood coach Nathan Buckley said after the win Ben Reid's performance up forward had made the match commitee's job difficult with Mason Cox likely to return from a foot injury.

Meanwhile Buckley told 3AW on Saturday he remained in the dark to a large extent about how the anti-doping investigation into defender Sam Murray was progressing.

AFL CEO Gill McLachlan said on Friday the case involving Murray, who tested positive to a banned substance in August last year, was moving towards its conclusion with the 21-year-old potentially facing a four-year ban after he tested positive after a game to a substance banned on match day.

Buckley said the club and the players provided support in a personal sense to Murray but they generally steered clear of the details of the case when speaking to him.

"He is in limbo. [There are] ongoing discussions and investigations by ASADA and the time that it takes for them to come to their conclusions are tough on everyone," Buckley said.

"[We're] looking for an outcome sooner than later so he can actually have something concrete to work from."