RICHMOND premiership players Nick Vlastuin and Daniel Rioli are 50/50 chances to face Fremantle this Sunday after suffering injuries over the weekend.

Intercept defender Vlastuin injured his ankle and left the ground for treatment during the disappointing loss to the Western Bulldogs but managed to play out the match.

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Rioli has been battling after a series of knocks over the past few matches, with his latest issues a corked quad and general soreness.

The classy forward also played out the game but was noticeably limited in his movement.

The club has said key back David Astbury is considered a "probable" return this weekend after missing Saturday's loss with an ankle injury.

Half-back flanker Oleg Markov is also set to return to football at some level, having recovered nearly a month faster than expected from surgery on a torn meniscus in his knee.

However, in bad news, Callum Moore badly injured his ankle in the VFL's win over Williamstown on Sunday.

Moore is set for an extended period on the sidelines, with the club rating the injury, a small fracture as well as ligament and tendon damage, as requiring a "medium-to-long-term" recovery.

There is no exact time-frame yet as the 22-year-old needs to meet with a specialist to see if surgery is required.

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The Tigers have their leadership group of Trent Cotchin (hamstring), Alex Rance (ACL) and Jack Riewoldt (PCL) out of action, as well as Jack Graham (hamstring) and indefinite pair Jayden Short (elbow) and Shaun Grigg (knee and hip). Draftee Luke English (tonsillitis) is also unavailable this week.