Celebrities and members of the fashion industry took to social media after news of fashion designer Kate Spade's sudden death from an apparent suicide broke Tuesday. The 55-year-old was reportedly found dead in her Manhattan apartment with a note.

Rosie O'Donnell first reached out to Spade's brother-in-law, David, to offer her condolences.

"@DavidSpade - all my love to u dave -" O'Donnell tweeted.

American fashion designer Liz Lange called Spade the "nicest woman" and creator of the "most iconic brand."

"The first person to compliment me on Liz Lange Maternity when I first started. ... I am heart broken by this news," Lange tweeted.

Chelsea Clinton recalled getting her first Kate Spade handbag from her grandmother when she was a college student.

"I still have it," Clinton wrote on Twitter. "Holding Kate’s family, friends and loved ones in my heart."

Plus-size model Tess Holliday said she was "crushed" by the news.

"Kate Spade & her brand have always been so kind to me the past couple years. ... Suicide isn’t 'the easy way out' and shouldn’t be mocked. My heart goes out to her family & team today," Holliday commented.

Singer Josh Groban offered his "love" to Spade's family.

"Depression does not discriminate and comes without warning. RIP Kate Spade. Love to her family," he tweeted.

"The Real Housewives of New York City" star Bethenny Frankel also took to Twitter.

"Some people are just completely tormented despite meds & friends & support. Some simply cannot deal & it is part of their DNA. Some can cope. It’s truly tragic to imagine the pain taking you there," Frankel wrote.

Fashion designer Kenneth Cole also tweeted about Spade.

“'I believed that I could, so I did.' She alone didn’t change the handbag world but she was an inspiring accessory. #KateSpade #RIP," he wrote in a tweet that was apparently later deleted.

Talinda Bennington, widow of Linkin Park singer Chester, who committed suicide, offered her "deepest condolences to Kate Spade’s family and friends."

Ivanka Trump said the designer's "tragic passing is a painful reminder that we never truly know another’s pain or the burden they carry."

The Kate Spade New York Twitter account posted a statement online about her death.

"We honor all the beauty she brought into this world," it read.

Read on to see other reactions to Spade's death.