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Ontario Provincial Police say a 59-year-old Toronto man has been arrested in a road rage investigation after five people, including three children, were injured in a three-vehicle crash on Highway 401.

The collision happened around 12:45 a.m. Monday in the eastbound collector lanes near Leslie Street.

Toronto paramedics said one child under the age of two was rushed to a trauma centre in serious condition and two other children were taken to hospital with minor injuries.

READ MORE: Driver killed after tractor-trailer crash on Hwy. 401 in Oshawa

Sgt. Kerry Schmidt identified the youngest child hurt as a 17-month-old who remains in critical condition.

Authorities said two adults, women in their 50s and 60s, were also transported to hospital with minor injuries.

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Police announced on Tuesday the man is facing dangerous driving-related charges. He is scheduled to appear in court on Wednesday for a bail hearing.

“There’s no place for road rage anywhere in our society or on our highways,” Schmidt said on Twitter Tuesday evening, adding further details will be released on Wednesday.

— With files from Nick Westoll

Arrest made in #RoadRage investigation.17 month old in critical condition,59 year old man from Toronto in custody https://t.co/TzJakSF45q — Sgt Kerry Schmidt (@OPP_HSD) July 17, 2018

59 year old man from Toronto has been arrested and is facing charges of dangerous driving causing bodily harm X2.

He is being held in custody for a bail hearing on Wednesday.

The 17 month old girl remains in critical condition. #RoadRage pic.twitter.com/z2ZgYEgfZt — Sgt Kerry Schmidt (@OPP_HSD) July 17, 2018

CLEARED: ROAD CLOSURE: #Hwy401 EB collectors at Leslie St: All lanes REOPENED. ^aw — OPP GTA Traffic (@OPP_GTATraffic) July 16, 2018