The timing of the latest Hillary Clinton email probe suggests there may be some significant information in the case, two Republican congressmen told CNBC on Friday.

With just 11 days until the election, the Federal Bureau of Investigation sent a letter to lawmakers on Friday stating it is investigating new emails related to Clinton.

The emails were discovered during an FBI investigation in which the devices of former Congressman Anthony Weiner and Clinton aide Huma Abedin were seized, NBC News confirmed. The New York Times first reported the news.

"I would imagine that they have some evidence that's relatively significant to go through the extraordinary step to write a letter to the leaders of all these committees," Rep. Ron DeSantis, R-Florida, said in an interview with CNBC's "Closing Bell." DeSantis is a member of the House Oversight and Government Reform Committee.

Rep. Jim Jordan, R-Ohio, told "Power Lunch" he has taken issue with FBI Director James Comey's decision to not prosecute Clinton and the fact that five people got immunity agreements in the case. Because of that, he thinks the probe into the new emails sends a strong message.

"We don't know what it is but it sure seems like it must be something pretty darn important for that fact pattern to play out and for them to announce just a week and a half before an election that they are going to reexamine things and look at these new emails," said Jordan, who sits on the House Oversight and Judiciary Committees.