PARIS — Albert Uderzo, a co-creator of Asterix, one of France’s most revered and longest-running comic book series, died on Tuesday at his home in Neuilly-sur-Seine, a suburb of Paris. He was 92.

His death was confirmed by Dargaud, the former publisher of the Asterix comic books. Bernard de Choisy, Mr. Uderzo’s son-in-law, told the Agence France-Presse that the cause was a heart attack.

Mr. Uderzo and the writer René Goscinny created Asterix in 1959, filling the series with puns, regional stereotypes and anachronistic references to French culture as it followed the adventures of its main character, an ancient Gaul named Asterix, a mustachioed figure in a battle helmet.

The series is joined perhaps only by Tintin and Mickey Mouse in the pantheon of comic book and cartoon characters with uninterrupted universal appeal. In 1966, France’s first space satellite was named Asterix.