Federal MP Clive Palmer says his wife will have a tilt at politics in Queensland.

Anna Palmer is seeking preselection for the Palmer United Party (PUP) for the Gold Coast seat of Gaven, taking on independent MP Dr Alex Douglas.

Dr Douglas quit the PUP in August, alleging a "jobs for the boys" culture.

He said yesterday that he doubted Mr Palmer would run a candidate at the next state election.

Mr Palmer said Dr Douglas was mistaken.

"It's interesting that Alex Douglas says that because we have got three candidates that want to stand in the seat of Gaven his seat," Mr Palmer said.

"There are three great candidates going up for preselection in the next two weeks to make a final determination, and one of them is my wife Anna.

"She has put her name in to stand against Alex Douglas at the next election.

"I think we have got a lot of PUP supporters inside Gaven and, after all, it was held by our party until Alex Douglas spat the dummy.

"Now it is a chance to return back to the Palmer United Party, maybe under my wife or maybe under one of the other two candidates."

Dr Douglas shrugged off the possibility of Mrs Palmer running against him.

"This is just: 'I'm angry with Alex Douglas because he stated the obvious'," he said.

"The PUP experiment as a state experiment is finished, it's over, move on."

Mr Palmer said he would also have PUP candidates in Mudgeeraba, Maryborough and Kawana.