Penne, Italy (CNN) Rescuers were searching into the night Thursday for any survivors of an avalanche that killed at least two people and blasted a resort hotel in central Italy.

As night fell, as many as 30 people were thought to be still inside the wreckage of the Hotel Rigopiano, Italy's Civil Protection Department said. Some could have survived in air pockets, officials said, although cold temperatures would endanger any survivors.

The avalanche swallowed the four-star hotel, at the foot of the Gran Sasso mountain about (135 kilometers) 85 miles northeast of Rome, Wednesday night after a series of earthquakes in the region that day.

Road crews had cleared much of the snow and fallen trees by nighttime Thursday, finally allowing heavy rescue equipment to reach the hotel. Snow machines and helicopters had earlier taken searchers, including dogs, up the mountain.

Officials based estimates of the missing on guest registration and staff numbers, but said it was possible that some people had escaped before the avalanche hit.

The hotel has 43 rooms, according to website TripAdvisor.

Italian fire department spokesman Luca Cari, who was at the scene, told CNN that the hotel had been "completely slammed" in the avalanche and debris was scattered as far as 100 meters from the hotel structure, making the search area large.

Two people were rescued from the site of the hotel, Civil Protection Department chief Fabrizio Curcio told journalists, but rescuers using search dogs have otherwise seen no sign of life.

"We are calling out but no one is answering," a searcher told Italian state media ANSA.

One man, vacationing with his wife and two children, 6 and 8, said he missed being caught in the destruction only because he had walked to his car just before the avalanche hit. The whereabouts of his wife and children remained unknown Thursday.

Firefighters told ANSA the hotel had been "swept away" and buried by tons of snow, and that there were mostly uprooted trees and debris at the hotel site. Two bodies had been recovered more than 24 hours after the avalanche hit.

An elderly farmer also died in the same region of Abruzzo on Wednesday when his barn collapsed

Rescuers ski to disaster zone

Video recorded by rescue teams showed what appears to be a smashed wall or window in the hotel's lobby, with tree branches, snow and other debris piled on the floor.

Snow and debris broke through windows or a thin wall into the Hotel Rigopiano.

Curcio explained that dealing with earthquakes and an avalanche at the same time caused difficulties in the rescue operation and even confusion among the affected population over how to respond.

"For the weather, you tell people to stay in their homes, while for the earthquake, citizens must be brought outside. Putting together these two elements is extremely complicated," he said.

Rescuers dig for survivors at the hotel Thursday following the avalanche.

Rescuers battled blizzards and strong winds to reach the site, some having to ski for several kilometers in the darkness to get there because some roads were impassable.

When they arrived, they found only the building's top story and roof visible above the snow, Italy's Mountain Rescue Service said on social media. It also posted a picture of rescuers digging for survivors.

This file photo shows The Hotel Rigopiano, which sits at an altitude of 1,200 meters (nearly 4,000 feet).

Italy's fire department posted a photo on Twitter showing rescuers being dropped into the area by helicopter.

Italian Prime Minister Paolo Gentiloni said the amount of this week's snowfall in the country is something that hasn't been seen in decades.

The Hotel Rigopiano in central Italy, in a photo taken before the avalanche.

CNN Meteorologist Brandon Miller said heavy snowfall in the last 24 hours measured 70 centimeters (nearly 28 inches) and over the past week, snow accumulations were more than 3 meters (about 10 feet) in the mountains. The risk of more avalanches is high, he said.

"The recent, historic snowfalls have created a very loose and unstable snowpack, which is why the avalanche danger is high on all steep slopes."

Photos: Avalanche buries Italian hotel The coffin of avalanche victim Alessandro Giancaterino is carried to his funeral service in Farindola, central Italy, on Tuesday, January 24. A series of earthquakes that struck on January 18 caused an avalanche at the foot of Gran Sasso mountain in central Italy, about 135 kilometers (85 miles) northeast of Rome, burying guests and staff of Hotel Rigopiano, a local mountain resort. Hide Caption 1 of 16 Photos: Avalanche buries Italian hotel Emergency crew members carry three puppies that were dug out from under the snow covering Hotel Rigopiano on Monday, January 23. Rescuers cheered the discovery of the dogs, whose survival brings hope for those people who are still missing. Hide Caption 2 of 16 Photos: Avalanche buries Italian hotel Italian rescuers and volunteers continue a rescue operation on Sunday, January 22 at the site of the avalanche that inundated Hotel Rigapiano. Hide Caption 3 of 16 Photos: Avalanche buries Italian hotel Migrants volunteering with the Italian Red Cross stand ready at the avalanche emergency operations center at Penna, central Italy, on Saturday, January 21. Hide Caption 4 of 16 Photos: Avalanche buries Italian hotel A rescuer rests at a sports complex turned emergency coordination center in Penne on January 21. Hide Caption 5 of 16 Photos: Avalanche buries Italian hotel One of three children rescued from the avalanche zone is transported to a hospital in Pescara, on Friday, January 20. Hide Caption 6 of 16 Photos: Avalanche buries Italian hotel Another of the three children rescued on Friday is carried by rescuers to the hospital in Pescara. Hide Caption 7 of 16 Photos: Avalanche buries Italian hotel An aerial view shows the roof and top floor of the three-story Hotel Rigopiano buried in snow after the avalanche struck at the foot of Gran Sasso mountain in central Italy on Thursday, January 19. Hide Caption 8 of 16 Photos: Avalanche buries Italian hotel Rescuers stand by two cars submerged in snow as they work in front of the Rigopiano Hotel on January 19. Hide Caption 9 of 16 Photos: Avalanche buries Italian hotel A rescuer clears snow in front of the hotel. Hide Caption 10 of 16 Photos: Avalanche buries Italian hotel Rescue workers were met with an eerie silence Thursday when they reached Hotel Rigapiano, a four-star spa hotel struck by an avalanche. Hide Caption 11 of 16 Photos: Avalanche buries Italian hotel Rescuers are dropped by helicopter near the site of the avalanche. Weather conditions in the region made it difficult to access the area by road. Hide Caption 12 of 16 Photos: Avalanche buries Italian hotel Snow and rubble fill a hallway inside Hotel Rigopiano. The area is a popular ski destination for Italian tourists. Hide Caption 13 of 16 Photos: Avalanche buries Italian hotel Italian emergency crews operate at the site of the avalanche on January 19. Central Italy was hit by more than 10 earthquakes on Wednesday, January 18, four of them measuring magnitude 5 or above, according to the US Geological Survey. Hide Caption 14 of 16 Photos: Avalanche buries Italian hotel Damage from the avalanche is seen in an image taken from video shot by rescuers inside Hotel Rigopiano. Hide Caption 15 of 16 Photos: Avalanche buries Italian hotel Rescuers dig for avalanche survivors after skiing several kilometers through blizzard conditions to reach the hotel, on January 19. Hide Caption 16 of 16

Rescue efforts ongoing

Rescuers were still trying to get to other areas isolated by the avalanche, Gentiloni said, and authorities were hoping to bring power back to as many as 90,000 people who were left in darkness overnight from the extreme weather.

Central Italy was rocked by more than 10 earthquakes Wednesday, four of them above magnitude 5, according to the US Geological Survey.

An initial 5.3-magnitude quake hit in the morning near the town of of Amatrice, which was devastated by powerful earthquakes in August. The tremors continued for more than six hours, with one as strong as magnitude 5.7.

While the epicenter was 90 kilometers (about 55 miles) northeast of Rome, the quake was felt in the capital, sending people running from buildings in a panic.

All the aftershocks hit around Amatrice, in the mountainous regions of Marche, Lazio and Abruzzo.