The suicide rate in the United States increased 33% between 1999 and 2017, the Centers for Disease Control and Prevention reported Thursday — the latest in a troubling trend of reports showing more men and women, in nearly all states and across various racial and ethnic groups, dying by suicide. Experts say it’s a public health crisis.

In 1999, about 10.5 suicides occurred per 100,000 people, the CDC report said. In 2017, the rate was 14 per 100,000. The sharpest increases have been among adolescents and young adults. The only decrease in the suicide rate was seen among people over 75.

Among young adults, both men and women, the rate of suicide was highest among American Indians or Alaskan Natives. But among middle-aged individuals, the rate was highest for white men and women.

Researchers from Harvard Medical School and Tel Aviv University took a closer look at suicides among adolescents and young adults, groups in which suicide is the second leading cause of death.

In a report published Tuesday, they found there were 6,252 suicides of people aged 15 to 24 in 2017 — the highest number since 2000.