Melbourne radio listeners have turned their backs on the ABC's new breakfast show in droves following the departure of long-time host Red Symons.

Comedian Sami Shah and former 3RRR presenter Jacinta Parsons recorded a massive 2.9 point drop in audience share in Tuesday's radio ratings.

An ABC spokesman confirmed a drop in audience share was expected as a result of major programming changes in recent months.

"Breakfast audiences are down generally across most Melbourne stations," he said. "Changes to our programming will take time to settle in and we are confident that, over time, Melbourne audiences will discover and engage with our new content and presenters."