In human challenge trials, healthy participants are exposed to a pathogen under controlled conditions so that scientists can learn more about the disease it causes and more quickly see whether potential vaccines or treatments work. They have been used to develop vaccines and treatments for seasonal flu, typhoid, malaria, and cholera, among others. Researchers are exploring whether human challenge trials could support the development of vaccines and treatments for COVID-19.

1Day Sooner is a non-profit organization that advocates on behalf of potential COVID-19 challenge trial volunteers. You can learn more about our mission, operations, and team on our About Us page. Our four departments-- Advocacy, Communications, Research, and Organizing-- work on various fronts to involve 1Day Sooner volunteers in challenge trial preparation.

Sign up below if you would be interested to participate in a human challenge trial for COVID-19 and, potentially, advocate for the safe and rapid development of vaccines and treatments Please note: this is only an expression of interest. There will be multiple stages of registration and pre-qualification before selected volunteers can formally consent to participating in any human challenge trial (if ultimately approved and conducted). We will contact you with opportunities to participate in human challenge trials or related advocacy activities as they become available. We will not sell your information and will only use it as necessary to run our volunteer operations - full details are in our Privacy Policy on this website.

If you have any difficulties with the Microsoft form, please let us know at admin@1daysooner.org. If you have questions about something other than the technical performance of the form, please contact us at inquiries@1daysooner.org. Thank you!