CLEVELAND — Kristaps Porzingis has never excelled against the Cavaliers. Last season. in four Knicks losses, Porzingis shot 35 percent and averaged just 11.3 points.

If Porzingis continues the trend Sunday at Quicken Loans Arena, the Knicks will be in for a long night against LeBron James and the Cavaliers — no matter what point guard Frank Ntilikina provides.

With the Knicks’ first win out of the way after they routed the Nets at the Garden on Friday, the 1-3 club now has a giant task of facing the Cavaliers, who are teetering.

In following up their disgraceful loss Wednesday in Brooklyn, Cleveland fell to 3-3 after being pummeled Saturday in New Orleans, 123-101. The Cavaliers have shuffled their starting lineup four times in six games as they attempt to figure out the right chemistry after a season of Kyrie Irving-related upheaval.

In fact, James has been at point guard while old friend Derrick Rose sits out with an ankle injury. Rose could be saving himself to face the Knicks after his frosty goodbye.

Porzingis, meanwhile, is off to a hot start — scoring 30 or more points in three of the first four games.

“Cleveland is Cleveland,’’ Porzingis said. “They’re have a lot — LeBron — and it’s always tough to play against them. Especially me, I haven’t had great games or we as a team against Cleveland. Hopefully we can play the same way defensively against them and have a possibility of winning.’’

The Knicks ended their distinction as the last winless team Friday by stifling Brooklyn in a 107-86 bashing. They held the Nets to 40.5 percent shooting, communicated on defense and outrebounded them 55-34.

What changed? The point-guard situation saw a significant makeover as Jarrett Jack started in place of Ramon Sessions and a healthy Ntilikina made his Garden debut a smashing success after missing the previous two games. Ntilikina played stout defense and delighted the Garden fans with his snazzy playmaking — five assists in 20 minutes.

Sessions, meanwhile did not play — the scapegoat for all the players’ squawking about their offense being disorganized. There were allegations not everyone has learned coach Jeff Hornacek’s new sets.

Jack, who turned 34 Saturday, showed he isn’t ready for the rocking chair. He played a controlled game (eight points, five assists, seven rebounds) and now Sessions’ future becomes unclear. Jack already has become a strong mentor for Ntilikina.

Center Joakim Noah is set to return from a drug suspension on Nov. 13 when the Knicks host the Cavaliers, and a player will need to be released. Jack appeared headed for the waiver wire, but now everything is in flux, including the future playing status of combo guard Ron Baker.

Baker, Hornacek’s golden child, was not activated to face the Nets. The Knicks coach said Baker still is fighting an ankle injury from training camp.

Either way, if James moves to point guard Sunday, Jack figures he won’t get the defensive assignment, but that will go to swingman Courtney Lee. Jack, however, will get Rose if he starts against the Knicks.

The Cavaliers’ can play small and big as they wait indefinitely for All-Star point guard Isaiah Thomas’ return from a hip injury. Prominent players such as Dwyane Wade, Jae Crowder, Iman Shumpert and Kyle Korver have come off the bench.

“LeBron is in a zone,’’ Lee said. “We got to key on him and slow him down as much as possible and everybody has to try to help each other out on the defensive end.’’

The Cavaliers’ can play small and big as they wait indefinitely for All-Star point guard Isaiah Thomas’ return from a hip injury. Prominent players such as Dwyane Wade, Jae Crowder, Iman Shumpert and Kyle Korver have been coming off the bench.

After the Celtics’ Gordon Hayward suffered a catastrophic, season-ending leg injury, the Cavaliers are overwhelming favorites to make their fourth straight Finals. That would be eight straight Finals for James.

Lee made the Finals his rookie year with the Magic and hasn’t been close since.

“That just shows [James’] MVP status,’’ Lee said. “Taking multiple teams, different teams to the NBA Finals is not an easy task to do. It speaks volumes to his excellence. Our job is to try to slow him down and stop that.’’

The Knicks haven’t beaten Cleveland since the season opener of the 2014-15 campaign — James’ first game of his second Cleveland stint. It has been 10 straight losses, with a 13-point average margin of defeat.

Jack was traded in the summer of 2014 by the Cavaliers to Brooklyn to make room for James.

“He owes me a thank you,’’ Jack said.