JACKSONVILLE, Fla. -- The Jacksonville Jaguars might be without tight end Julius Thomas, defensive end Dante Fowler Jr., defensive end Jared Odrick and linebacker Dan Skuta because of injuries for Sunday’s game against Indianapolis.

All four players missed practice Wednesday and Thursday and coach Gus Bradley said the status of Thomas (elbow) and Fowler (shoulder) will be game-time decisions. Odrick and Skuta have not yet been ruled out, but it appears doubtful that either will play against the Colts.

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The Jaguars leave for London on Thursday evening and will arrive Friday morning. The final injury report will be released following the team's walk-through in London.

Thomas has caught 11 passes for 148 yards and a touchdown, and if he can’t play, the Jaguars will have just two healthy tight ends: Marcedes Lewis (seven catches, 85 yards, one TD) and second-year player Neal Sterling, who has played in 12 games in his career mainly on special teams. Ben Koyack had knee surgery last week and is out indefinitely.

Fowler is tied with rookie Yannick Ngakoue for the team lead with two sacks. Ngakoue would start in Fowler’s place.

Odrick missed last week’s game because of a triceps injury he suffered in a Week 2 loss to San Diego. Tyson Alualu started in his spot and would do so again against the Colts. Skuta has been dealing with a hip injury and rookie Myles Jack likely would get some of his reps should he not be able to play.