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Two people have been killed in a mass shooting after a gunman opened fire at a Madden NFL video game tournament in Jacksonville, Florida.

The horror shooting took place at a gaming venue called Good Luck Have Fun inside Chicago Pizza in Jacksonville Landing during a live Twitch streaming of the event.

Cops later named the suspect as David Katz, a 24-year-old from Baltimore, Maryland.

The shooter opened fire, killing two and wounding nine others before turning the gun on himself.

In footage streamed online through Twitch nine gunshots can be heard before there are several screams and shouts.

(Image: Twitch.tv)

As the shots sound, you can hear repeatedly “oh my god.”

Three people are confirmed dead by police, including the suspected gunman who was pronounced dead at the scene.

A manhunt was launched for a second suspect but police confirmed at 9.30pm GMT that there was only one shooter.

"We have no outstanding suspects at this time. No outstanding suspects," Jacksonville Sheriff Mike Williams said at a news conference. "We have one suspect in this case. He is deceased at the scene."

Witness Ryen Aleman told CNN: "As I was going in the restroom, I stayed in there, and I just heard -- there was just so many gunshots, at least 20 of them at the most."

(Image: GLHFGameBar/Twitter) (Image: CBS)

He said the shooter may have had a laser to assist his aim on the gun.

"I’m still shocked, I can hardly talk," Aleman said.

The Jacksonville Landing is an open-air marketplace with stores, bars and restaurants in downtown Jacksonville along the St Johns River.

(Image: Unknown)

Police confirmed there had been a "mass shooting" at the centre and warned people to stay away from the area - but they are yet to confirm any details about victims. President Trump has been briefed.

Terrified bystanders fled the scene with officers finding them hidden in locked areas of the commercial complex.

(Image: Unknown) (Image: CBS)

One witness said he ran so fast after hearing gunshot he lost his shoes.

The man, who didn't want to be identified, said: "I was just getting my pizza and then heard shots. It was scary."

Footage shows two young men playing in the Madden Championship Series when suddenly shots can be heard in the background.

The stream cuts out, but the audio is still live and people can be heard screaming out in pain in the background.

(Image: CBS) (Image: Twitch.tv)

Drini Gjoka was shot in the thumb an professional gamer 'Larry Legend' was also hit at least three times.

His mother Sujeil Lopez was at her home in Tampa Bay when she got a call her son, who goes by Larry, 25, had been shot.

“I have to get to him. I am four hours away from him and I have to get to my son,” she told the New York Times.

“He was shot three times, once on the nipple, once on his hand and somewhere else."

Memorial Hospital in Jacksonville, Florida is treating at least three patients that were involved in the gaming shooting, according to CNN.

Kyrie Curry shared footage the Twitch stream on Twitter, writing: "Oh my god someone just shot up the Jacksonville madden tournament. This is unreal I hope everyone is okay."

Jacksonville Police wrote on Twitter: "Mass shooting at the Jacksonville Landing. Stay far away from the area. The area is not safe at this time. STAY AWAY."

(Image: Twitch.tv) (Image: NBA 2K League)

We can't stress enough to stay away. Many blocks away," they said in a subsequent tweet.

The office added in another tweet: “We are finding many people hiding in locked areas at The Landing. We ask you to stay calm, stay where you are hiding. SWAT is doing a methodical search inside The Landing. We will get to you. Please don’t come running out.”

The area has now been secured.

The University of Florida Health Jacksonville is treating six patients. Five are stable, one is in serious condition, and they are aged between 20 to 35 years old.

CompLexity Gaming, which sponsored one of the players, confirmed the shooting at the event and said a gamer was “grazed in the hand” by a bullet.

Local news footage showed several ambulances, as well as firefighters and police officers, on the scene, as well as roads being blocked off in the downtown area.

The Bureau of Alcohol, Tobacco, Firearms and Explosives (ATF) is responding to the scene in Jacksonville Landing, a law enforcement source told CNN.

Coast Guard boats are patrolling the river.

Spectators watch the Madden tournaments, hoping to pick up skills and tips from more experienced gamers.

Madden NFL is an American football video game series developed by EA Tiburon for EA Sports.

The shooting took place at the southeast regional qualifying tournament for the Madden NFL 19 Classic tournament, which advertised a $5,000 grand prize and is open to anybody.