[Ms. Murkowski’s speech explaining why she voted against Judge Kavanaugh.]

Senator Joe Manchin III, Democrat of West Virginia

Mr. Manchin is seeking re-election in a state that President Trump won overwhelmingly, and he is trying to demonstrate to voters that he is not blindly aligned with the Democratic Party.

In 2017, Mr. Manchin voted to confirm Judge Neil M. Gorsuch, Mr. Trump’s first Supreme Court nominee, and a vote for Judge Kavanaugh could aid the senator’s campaign.

But the chief issue for the West Virginia senator is health care: Mr. Manchin, who has repeatedly voted against attempts to repeal the Affordable Care Act, has stressed that he wants the courts to preserve the act’s protections for people with pre-existing health conditions.

After meeting with Judge Kavanaugh, the senator said in a radio interview in July that he was not leaning in a particular direction, but found the judge to have “all the right qualities.” After the Senate vote on Friday morning, a spokesman said that Mr. Manchin would have nothing else to say on the matter until Saturday.

As sexual assault accusations against Judge Kavanaugh came out, Mr. Manchin stayed tight-lipped. Last week, however, he released a statement calling the confirmation process “partisan and divisive,” but also supporting a delay in the process to accommodate an F.B.I. investigation.

In an interview on Monday with WV News, a local news outlet, Mr. Manchin said he would base his vote on the findings of the investigation.

“If there’s nothing conclusive,” he said, “then it’ll be based on the merits of him being qualified.”