U.S. stocks closed sharply lower on Wednesday, with the S&P 500 and Dow industrials finishing at to their lowest levels since Sep 29, 2015. Consumer discretionary and health-care stocks led the broad selloff. The S&P 500 SPX, +0.04% closed 48.40 points, or 2.5%, lower at 1,890.28. The Dow Jones Industrial Average DJIA, -0.16% dropped 364.81 points, or 2.2%, to 16,151.41. Meanwhile, the Nasdaq Composite COMP, +0.31% ended the day down 159.85 points, or 3.4%, at 4,526.06.