The wife of a man who has been missing for two nights in Victoria's Alpine region has made a tearful plea for information about her husband.

Key points: Taddeo 'Ted' Haigh last seen at 9:30pm Sunday

Taddeo 'Ted' Haigh last seen at 9:30pm Sunday He had been staying in Sawmill Settlement for the Anzac Day long weekend

He had been staying in Sawmill Settlement for the Anzac Day long weekend Police, SES searching with aircraft and dirt bikes

Taddeo Haigh, 31, known as Ted, had been staying at a holiday home at Sawmill Settlement, near Merrijig, with his wife and friends to go mountain biking for the Anzac Day long weekend.

He decided to go for a walk on Sunday night about 9:30pm and his wife, Elizabeth Haig, expected he would be back in half an hour.

When he did not return, Ms Haig got in the car and searched through the night before reporting him missing to police on Monday morning.

An emotional Ms Haig said it was "really hard not knowing where he is".

"I feel like he's either lost or that he's been injured and can't actually get back. It's just really hard thinking about that," she said.

"If anyone has seen him walking or seen someone trying to get a ride somewhere or any items of clothing that could belong to him or any information at all, we'd be really grateful to receive that."

Police and SES volunteers searched the area late into Monday night and police aircraft and Parks Victoria joined the search at first light on Tuesday.

Police officers on dirt bikes were also scouring through the rough terrain.

Temperatures in the area dipped down to 3 degrees Celsius over the past two nights.

'No indication of anything sinister'

Senior Sergeant Mark Helyer said while Mr Haigh would have been exposed to the elements, he was fit and healthy.

"There's nothing suspicious in relation to the person's disappearance. We're essentially looking or a lost young man," he said.

Police say Ted Haigh is very fit and had been mountain biking in the area. ( Supplied )

"We don't have any indication that there is anything sinister in this situation whatsoever.

"Unfortunately the terrain outside the back door of the house is wilderness.

"We're looking at steep terrain, cliffs to gullies and mineshafts. So it's a very protracted search and it's very resource-heavy."

Senior Sergeant Helyer said there was limited coverage in the area for Mr Haig's phone company, Optus.

"We have had no phone activity since 7:00pm Sunday, the evening he went missing," he said.

"The frustration there is, [phones are] such a great tool to physically locate someone but if the tool is turned off, we can't use it."

Mr Haigh left the house wearing a grey zip-up hoodie, dark jeans and brown shoes.

He has been described as Caucasian, with a medium build and light brown hair.