Italy has announced it is working to help relocate the family of a Pakistani Christian woman acquitted of blasphemy charges, amid pleas of asylum from her husband who says the family's life is in danger in Pakistan.

Key points: Italy says it will do all that is "humanly possible" to help

Italy says it will do all that is "humanly possible" to help Canada and Germany looking into granting asylum to acquitted woman

Canada and Germany looking into granting asylum to acquitted woman Hard-line Islamists are demanding that Asia Bibi be executed

The Foreign Ministry said it was coordinating with other countries to ensure the safety for Asia Bibi and her family, who are facing increasing demands from hardline Islamists for her execution.

In a statement, the ministry said it was ready to act on whatever the Italian Government might decide, an indication that an offer of asylum might be in the offing.

Italy's anti-migrant interior minister Matteo Salvini stressed that he would do "all that is humanly possible" to ensure Ms Bibi and her family are safe, either in Italy or another country.

Asia Bibi and her family have always maintained her innocence. ( AP: File )

Ms Bibi's case has been closely followed in Italy for years, with Pope Francis meeting earlier this year with her family in a show of solidarity.

The offer came just one day after Ms Bibi's husband, Ashiq Masih, himself appealed to US President Donald Trump and reached out to Canada for assistance.

"Please help us, we are in trouble in Pakistan," Mr Masih appealed to Mr Trump in a brief video message.

Ms Bibi was convicted and sentenced to death in 2010 for insulting Islam's prophet, but Pakistan's top court acquitted her last week.

The acquittal set off violent protests from members of the ultra-right Tehreek-e-Labaik (TLP) party, who shut down major roads in Pakistan's biggest cities over three days, torching scores of vehicles and attacking government and public property.

Mohammed Ahmed Ludhianvi, right, chief of radical Islamist party Ahle Sunnat Wal Jammat, has condemned the decision to acquit Asia Bibi. ( AP: B.K. Bangash )

They have also called for the murder of the Supreme Court judges who acquitted Ms Bibi and labelled Prime Minister Imran Khan and the country's army chief enemies of Islam.

Police said more than 150 people were arrested on charges of arson, vandalism and violence.

They have threatened to escalate the protests if she is permitted to leave the country, prompting the Government to impose a travel ban on Ms Bibi until her case is reviewed.

"There will be a war if they send Asia out of country," TLP leader Khadim Hussain Rizvi said after the deal with the Government was reached.

Ms Bibi's lawyer, Saiful Mulook, fled to the Netherlands earlier this week because of fears for the safety of his family.

Ms Bibi was convicted of blasphemy in 2010 for allegedly making derogatory remarks about Islam after neighbours objected to her drinking water from their glass because she was not Muslim.

She has always denied committing blasphemy.

Federal minister for minorities Shahbaz Bhatti was killed after calling for her release.

Sorry, this video has expired Hard-line Islamists protest for Christian woman to be executed for blasphemy

Two other western countries have weighed into the case that has caused global outrage, with German Chancellor Angela Merkel's conservative party advocating for granting Ms Bibi and her family asylum.

On Tuesday, Canada's foreign minister, Chrystia Freeland, said Ms Bibi's safety was a "central priority for our government", after meting with her European Union counterpart, Federica Mogherini, in Montreal.

"Canada calls on Pakistan to take all measures necessary to ensure the safety and security of Asia Bibi and her family," Ms Freeland said. "Canada is prepared to do everything we can."

Reuters/AP