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Katelyn D. Boatwright, Morgan L. Sperry. Accuracy of Medical Marijuana Claims Made by Popular Websites. Journal of Pharmacy Practice 2020 , 33 (4) , 457-464. 33 (4) , 457-464. https://doi.org/10.1177/0897190018818907

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Galit Weinstein, Sharon R. Sznitman. The implications of late-life cannabis use on brain health: A mapping review and implications for future research. Ageing Research Reviews 2020 , 59 , 101041. 59 , 101041. https://doi.org/10.1016/j.arr.2020.101041

Tiyyaba Furqan, Sidra Batool, Rabia Habib, Mamoona Shah, Huba Kalasz, Ferenc Darvas, Kamil Kuca, Eugenie Nepovimova, Sajida Batool, Syed M Nurulain. Cannabis Constituents and Acetylcholinesterase Interaction: Molecular Docking, In Vitro Studies and Association with CNR1 rs806368 and ACHE rs17228602. Biomolecules 2020 , 10 (5) , 758. 10 (5) , 758. https://doi.org/10.3390/biom10050758

Roy Upton. Cannabis (Marijuana) and Cannabinoids. 2020 ,,, 470-483.e5. ,, 470-483.e5. https://doi.org/10.1016/B978-0-323-43044-9.00061-3

Anees Bahji, Arthi Chinna Meyyappan, Emily R. Hawken. Cannabinoids for the Neuropsychiatric Symptoms of Dementia: A Systematic Review and Meta-Analysis. The Canadian Journal of Psychiatry 2019 , 17 , 070674371989271. 17 , 070674371989271. https://doi.org/10.1177/0706743719892717

Juan A. Páez, Nuria E. Campillo. Innovative Therapeutic Potential of Cannabinoid Receptors as Targets in Alzheimer’s Disease and Less Well-Known Diseases. Current Medicinal Chemistry 2019 , 26 (18) , 3300-3340. 26 (18) , 3300-3340. https://doi.org/10.2174/0929867325666180226095132

Robert J. Silver. The Endocannabinoid System of Animals. Animals 2019 , 9 (9) , 686. 9 (9) , 686. https://doi.org/10.3390/ani9090686

Carlos Jimenez Naranjo, Ashleigh L. Osborne, Katrina Weston-Green. Effect of cannabidiol on muscarinic neurotransmission in the pre-frontal cortex and hippocampus of the poly I:C rat model of schizophrenia. Progress in Neuro-Psychopharmacology and Biological Psychiatry 2019 , 94 , 109640. 94 , 109640. https://doi.org/10.1016/j.pnpbp.2019.109640

C Siciliano, Lucia Bartella, F. Mazzotti, D Aiello, A Napoli, P De Luca, A Temperini. 1 H NMR quantification of cannabidiol (CBD) in industrial products derived from Cannabis sativa L. (hemp) seeds. IOP Conference Series: Materials Science and Engineering 2019 , 572 , 012010. 572 , 012010. https://doi.org/10.1088/1757-899X/572/1/012010

Rui Rodrigues, Diogo Lourenço, Sara Paulo, Joana Mateus, Miguel Ferreira, Francisco Mouro, João Moreira, Filipa Ribeiro, Ana Sebastião, Sara Xapelli. Cannabinoid Actions on Neural Stem Cells: Implications for Pathophysiology. Molecules 2019 , 24 (7) , 1350. 24 (7) , 1350. https://doi.org/10.3390/molecules24071350

Nevenka Kopjar, Nino Fuchs, Suzana Žunec, Anja Mikolić, Vedran Micek, Goran Kozina, Ana Lucić Vrdoljak, Irena Brčić Karačonji. DNA Damaging Effects, Oxidative Stress Responses and Cholinesterase Activity in Blood and Brain of Wistar Rats Exposed to Δ9-Tetrahydrocannabinol. Molecules 2019 , 24 (8) , 1560. 24 (8) , 1560. https://doi.org/10.3390/molecules24081560

Saba Tahir Tanoli, Muhammad Ramzan, Abbas Hassan, Abdul Sadiq, Muhammad Saeed Jan, Farhan A. Khan, Farhat Ullah, Haseen Ahmad, Maria Bibi, Tariq Mahmood, Umer Rashid. Design, synthesis and bioevaluation of tricyclic fused ring system as dual binding site acetylcholinesterase inhibitors. Bioorganic Chemistry 2019 , 83 , 336-347. 83 , 336-347. https://doi.org/10.1016/j.bioorg.2018.10.035

Michelle Sexton, Carrie Cuttler, Laurie K. Mischley. A Survey of Cannabis Acute Effects and Withdrawal Symptoms: Differential Responses Across User Types and Age. The Journal of Alternative and Complementary Medicine 2019 , 25 (3) , 326-335. 25 (3) , 326-335. https://doi.org/10.1089/acm.2018.0319

Joana Gonçalves, Tiago Rosado, Sofia Soares, Ana Simão, Débora Caramelo, Ângelo Luís, Nicolás Fernández, Mário Barroso, Eugenia Gallardo, Ana Duarte. Cannabis and Its Secondary Metabolites: Their Use as Therapeutic Drugs, Toxicological Aspects, and Analytical Determination. Medicines 2019 , 6 (1) , 31. 6 (1) , 31. https://doi.org/10.3390/medicines6010031

Lucia Marchetti, Virginia Brighenti, Maria Rossi, Johanna Sperlea, Federica Pellati, Davide Bertelli. Use of 13C-qNMR Spectroscopy for the Analysis of Non-Psychoactive Cannabinoids in Fibre-Type Cannabis sativa L. (Hemp). Molecules 2019 , 24 (6) , 1138. 24 (6) , 1138. https://doi.org/10.3390/molecules24061138

Giuseppina Talarico, Alessandro Trebbastoni, Giuseppe Bruno, Carlo de Lena. Modulation of the Cannabinoid System: A New Perspective for the Treatment of the Alzheimer’s Disease. Current Neuropharmacology 2019 , 17 (2) , 176-183. 17 (2) , 176-183. https://doi.org/10.2174/1570159X16666180702144644

Joshua A. Hartsel, Kyle Boyar, Andrew Pham, Robert J. Silver, Alexandros Makriyannis. Cannabis in Veterinary Medicine: Cannabinoid Therapies for Animals. 2019 ,,, 121-155. ,, 121-155. https://doi.org/10.1007/978-3-030-04624-8_10

Md Ruhul Amin, Declan W. Ali. Pharmacology of Medical Cannabis. 2019 ,,, 151-165. ,, 151-165. https://doi.org/10.1007/978-3-030-21737-2_8

Thomas M. Clark, Jessica M. Jones, Alexis G. Hall, Sara A. Tabner, Rebecca L. Kmiec. Theoretical Explanation for Reduced Body Mass Index and Obesity Rates in Cannabis Users. Cannabis and Cannabinoid Research 2018 , 3 (1) , 259-271. 3 (1) , 259-271. https://doi.org/10.1089/can.2018.0045

Yu-Ling Xu, Feng-Ye Li, Ferdinand Ndikuryayo, Wen-Chao Yang, Hong-Mei Wang. Cholinesterases and Engineered Mutants for the Detection of Organophosphorus Pesticide Residues. Sensors 2018 , 18 (12) , 4281. 18 (12) , 4281. https://doi.org/10.3390/s18124281

Maria S. Aymerich, Ester Aso, Miguel A. Abellanas, Rosa M. Tolon, Jose A. Ramos, Isidre Ferrer, Julian Romero, Javier Fernández-Ruiz. Cannabinoid pharmacology/therapeutics in chronic degenerative disorders affecting the central nervous system. Biochemical Pharmacology 2018 , 157 , 67-84. 157 , 67-84. https://doi.org/10.1016/j.bcp.2018.08.016

Ethan B. Russo. Cannabis Therapeutics and the Future of Neurology. Frontiers in Integrative Neuroscience 2018 , 12 12 https://doi.org/10.3389/fnint.2018.00051

Tamires Amabile Valim Brigante, Flavia R. Abe, Antônio Waldo Zuardi, Jaime Eduardo Cecílio Hallak, José Alexandre S. Crippa, Danielle P. de Oliveira. Cannabidiol did not induce teratogenicity or neurotoxicity in exposed zebrafish embryos. Chemico-Biological Interactions 2018 , 291 , 81-86. 291 , 81-86. https://doi.org/10.1016/j.cbi.2018.06.008

, Janis Rusko, Ferdinando Febbraio. Development of an automated multienzymatic biosensor for risk assessment of pesticide contamination in water and food. EFSA Journal 2018 , 16 16 https://doi.org/10.2903/j.efsa.2018.e16084

Marjolein Soethoudt, Georgios Alachouzos, Eva J. van Rooden, María Dolores Moya-Garzón, Richard J.B.H.N. van den Berg, Laura H. Heitman, Mario van der Stelt. Development of a Cannabinoid-Based Photoaffinity Probe to Determine the Δ 8/9 -Tetrahydrocannabinol Protein Interaction Landscape in Neuroblastoma Cells. Cannabis and Cannabinoid Research 2018 , 3 (1) , 136-151. 3 (1) , 136-151. https://doi.org/10.1089/can.2018.0003

Eric P. Baron. Medicinal Properties of Cannabinoids, Terpenes, and Flavonoids in Cannabis, and Benefits in Migraine, Headache, and Pain: An Update on Current Evidence and Cannabis Science. Headache: The Journal of Head and Face Pain 2018 , 58 (7) , 1139-1186. 58 (7) , 1139-1186. https://doi.org/10.1111/head.13345

Edward J. Calabrese, Alberto Rubio-Casillas. Biphasic effects of THC in memory and cognition. European Journal of Clinical Investigation 2018 , 48 (5) , e12920. 48 (5) , e12920. https://doi.org/10.1111/eci.12920

Dvory Namdar, Moran Mazuz, Aurel Ion, Hinanit Koltai. Variation in the compositions of cannabinoid and terpenoids in Cannabis sativa derived from inflorescence position along the stem and extraction methods. Industrial Crops and Products 2018 , 113 , 376-382. 113 , 376-382. https://doi.org/10.1016/j.indcrop.2018.01.060

Dvory Namdar, Hinanit Koltai. Medical Cannabis for the Treatment of Inflammation. Natural Product Communications 2018 , 13 (3) , 1934578X1801300. 13 (3) , 1934578X1801300. https://doi.org/10.1177/1934578X1801300304

Umalee Namdaung, Anan Athipornchai, Thongchai Khammee, Mayuso Kuno, Sunit Suksamrarn. 2-Arylbenzofurans from Artocarpus lakoocha and methyl ether analogs with potent cholinesterase inhibitory activity. European Journal of Medicinal Chemistry 2018 , 143 , 1301-1311. 143 , 1301-1311. https://doi.org/10.1016/j.ejmech.2017.10.019

Valerio Chiurchiù, Mario van der Stelt, Diego Centonze, Mauro Maccarrone. The endocannabinoid system and its therapeutic exploitation in multiple sclerosis: Clues for other neuroinflammatory diseases. Progress in Neurobiology 2018 , 160 , 82-100. 160 , 82-100. https://doi.org/10.1016/j.pneurobio.2017.10.007

OmarM.E. Abdel-Salam, AmanyA Sleem, EmanR Youness, FatmaA Morsy. Preventive effects of cannabis on neurotoxic and hepatotoxic activities of malathion in rat. Asian Pacific Journal of Tropical Medicine 2018 , 11 (4) , 272. 11 (4) , 272. https://doi.org/10.4103/1995-7645.231467

Domagoj Markovic, Dina Bošnjak, Tonci Brkovic, Milka Jeric, Zana Rubic, Ana Vuica Vukasović, Livia Puljak, . Cannabinoids for the treatment of dementia. Cochrane Database of Systematic Reviews 2017 , 24 24 https://doi.org/10.1002/14651858.CD012820

Syed H. Omar, Christopher J. Scott, Adam S. Hamlin, Hassan K. Obied. The protective role of plant biophenols in mechanisms of Alzheimer's disease. The Journal of Nutritional Biochemistry 2017 , 47 , 1-20. 47 , 1-20. https://doi.org/10.1016/j.jnutbio.2017.02.016

Sabrina Jarvis, Sean Rassmussen, Blaine Winters. Role of the Endocannabinoid System and Medical Cannabis. The Journal for Nurse Practitioners 2017 , 13 (8) , 525-531. 13 (8) , 525-531. https://doi.org/10.1016/j.nurpra.2017.05.014

Balapal S. Basavarajappa, Madhu Shivakumar, Vikram Joshi, Shivakumar Subbanna. Endocannabinoid system in neurodegenerative disorders. Journal of Neurochemistry 2017 , 142 (5) , 624-648. 142 (5) , 624-648. https://doi.org/10.1111/jnc.14098

Yung-Chih Kuo, Rajendiran Rajesh. A critical overview of therapeutic strategy and advancement for Alzheimer's disease treatment. Journal of the Taiwan Institute of Chemical Engineers 2017 , 77 , 92-105. 77 , 92-105. https://doi.org/10.1016/j.jtice.2017.05.011

Ayesha Khan, Anne Corbett, Clive Ballard. Emerging treatments for Alzheimer’s disease for non-amyloid and non-tau targets. Expert Review of Neurotherapeutics 2017 , 17 (7) , 683-695. 17 (7) , 683-695. https://doi.org/10.1080/14737175.2017.1326818

Tim Karl, Brett Garner, David Cheng. The therapeutic potential of the phytocannabinoid cannabidiol for Alzheimer’s disease. Behavioural Pharmacology 2017 , 28 , 142-160. 28 , 142-160. https://doi.org/10.1097/FBP.0000000000000247

S. Amanullah, K. Shivakumar, S. Hassan, A. Canfield, J. Cole. Synthetic Cannabinoids in Dementia. 2017 ,,, 828-838. ,, 828-838. https://doi.org/10.1016/B978-0-12-800756-3.00100-9

J. Wallach, T. Colestock, A. Adejare. Receptor Targets in Alzheimer’s Disease Drug Discovery. 2017 ,,, 83-107. ,, 83-107. https://doi.org/10.1016/B978-0-12-802810-0.00006-4

John C. Ashton, Megan J. Dowie, Michelle Glass. The Endocannabinoid System and Human Brain Functions. 2017 ,,, 115-186. ,, 115-186. https://doi.org/10.1016/B978-0-12-809666-6.00005-8

Jacob K. Akintunde, C. Abigail Irechukwu. Differential protection of black-seed oil on econucleotidase, cholinesterases and aminergic catabolizing enzyme in haloperidol-induced neuronal damage of male rats. Therapeutic Advances in Drug Safety 2016 , 7 (4) , 132-146. 7 (4) , 132-146. https://doi.org/10.1177/2042098616656812

Xiaoming Yang, Marpe Bam, Prakash S. Nagarkatti, Mitzi Nagarkatti. RNA-seq Analysis of δ9-Tetrahydrocannabinol-treated T Cells Reveals Altered Gene Expression Profiles That Regulate Immune Response and Cell Proliferation. Journal of Biological Chemistry 2016 , 291 (30) , 15460-15472. 291 (30) , 15460-15472. https://doi.org/10.1074/jbc.M116.719179

P. RajaRajeswari, S. Viswanadha Raju, Amira S. Ashour, Nilanjan Dey, Valentina E. Balas. Active site cavities identification of amyloid beta precursor protein: Alzheimer disease study. 2016 ,,, 319-324. ,, 319-324. https://doi.org/10.1109/INES.2016.7555143

Ester Aso, Isidro Ferrer. CB2 Cannabinoid Receptor As Potential Target against Alzheimer's Disease. Frontiers in Neuroscience 2016 , 10 10 https://doi.org/10.3389/fnins.2016.00243

Shane Darke, Michael Farrell. Which medications are suitable for agonist drug maintenance?. Addiction 2016 , 111 (5) , 767-774. 111 (5) , 767-774. https://doi.org/10.1111/add.13158

Nisachon Khunnawutmanotham, Nitirat Chimnoi, Patchreenart Saparpakorn, Supanna Techasakul. Synthesis and anti-acetylcholinesterase activity of scopoletin derivatives. Bioorganic Chemistry 2016 , 65 , 137-145. 65 , 137-145. https://doi.org/10.1016/j.bioorg.2015.12.002

Assaf Shelef, Yoram Barak, Uri Berger, Diana Paleacu, Shelly Tadger, Igor Plopsky, Yehuda Baruch. Safety and Efficacy of Medical Cannabis Oil for Behavioral and Psychological Symptoms of Dementia: An-Open Label, Add-On, Pilot Study. Journal of Alzheimer's Disease 2016 , 51 (1) , 15-19. 51 (1) , 15-19. https://doi.org/10.3233/JAD-150915

Zohara Sternberg. Promoting sympathovagal balance in multiple sclerosis; pharmacological, non-pharmacological, and surgical strategies. Autoimmunity Reviews 2016 , 15 (2) , 113-123. 15 (2) , 113-123. https://doi.org/10.1016/j.autrev.2015.04.012

Xiang-Qun Xie, Lirong Wang, Junmei Wang, Zhaojun Xie, Peng Yang, Qin Ouyang. In Silico Chemogenomics Knowledgebase and Computational System Neuropharmacology Approach for Cannabinoid Drug Research. 2016 ,,, 183-195. ,, 183-195. https://doi.org/10.1016/B978-0-12-800634-4.00019-6

Fatai Oladunni Balogun, Natu Thomas Tshabalala, Anofi Omotayo Tom Ashafa. Antidiabetic Medicinal Plants Used by the Basotho Tribe of Eastern Free State: A Review. Journal of Diabetes Research 2016 , 2016 , 1-13. 2016 , 1-13. https://doi.org/10.1155/2016/4602820

Jane Sachs, Erin McGlade, Deborah Yurgelun-Todd. Safety and Toxicology of Cannabinoids. Neurotherapeutics 2015 , 12 (4) , 735-746. 12 (4) , 735-746. https://doi.org/10.1007/s13311-015-0380-8

Javier Fernández-Ruiz, María A. Moro, José Martínez-Orgado. Cannabinoids in Neurodegenerative Disorders and Stroke/Brain Trauma: From Preclinical Models to Clinical Applications. Neurotherapeutics 2015 , 12 (4) , 793-806. 12 (4) , 793-806. https://doi.org/10.1007/s13311-015-0381-7

AIA Ahmed, MA van der Marck, GAH van den Elsen, MGM Olde Rikkert. Cannabinoids in late-onset Alzheimer's disease. Clinical Pharmacology & Therapeutics 2015 , 97 (6) , 597-606. 97 (6) , 597-606. https://doi.org/10.1002/cpt.117

Valerio Chiurchiù, Alessandro Leuti, Mauro Maccarrone. Cannabinoid Signaling and Neuroinflammatory Diseases: A Melting pot for the Regulation of Brain Immune Responses. Journal of Neuroimmune Pharmacology 2015 , 10 (2) , 268-280. 10 (2) , 268-280. https://doi.org/10.1007/s11481-015-9584-2

Martin Nimczick, Michael Decker. New Approaches in the Design and Development of Cannabinoid Receptor Ligands: Multifunctional and Bivalent Compounds. ChemMedChem 2015 , 10 (5) , 773-786. 10 (5) , 773-786. https://doi.org/10.1002/cmdc.201500041

Javier Fernández-Ruiz, Julián Romero, José A. Ramos. Endocannabinoids and Neurodegenerative Disorders: Parkinson’s Disease, Huntington’s Chorea, Alzheimer’s Disease, and Others. 2015 ,,, 233-259. ,, 233-259. https://doi.org/10.1007/978-3-319-20825-1_8

Arif Nisha Syad, Kasi Pandima Devi. Assessment of anti-amyloidogenic activity of marine red alga G. acerosa against Alzheimer’s beta-amyloid peptide 25–35. Neurological Research 2015 , 37 (1) , 14-22. 37 (1) , 14-22. https://doi.org/10.1179/1743132814Y.0000000422

Selim R Benbadis, Juan Sanchez-Ramos, Ali Bozorg, Melissa Giarratano, Kavita Kalidas, Lara Katzin, Derrick Robertson, Tuan Vu, Amanda Smith, Theresa Zesiewicz. Medical marijuana in neurology. Expert Review of Neurotherapeutics 2014 , 14 (12) , 1453-1465. 14 (12) , 1453-1465. https://doi.org/10.1586/14737175.2014.985209

Sabrina Giacoppo, Giuseppe Mandolino, Maria Galuppo, Placido Bramanti, Emanuela Mazzon. Cannabinoids: New Promising Agents in the Treatment of Neurological Diseases. Molecules 2014 , 19 (11) , 18781-18816. 19 (11) , 18781-18816. https://doi.org/10.3390/molecules191118781

Ornelio Rosati, Federica Messina, Azzurra Pelosi, Massimo Curini, Vanessa Petrucci, Jürg Gertsch, Andrea Chicca. One-pot heterogeneous synthesis of Δ3-tetrahydrocannabinol analogues and xanthenes showing differential binding to CB1 and CB2 receptors. European Journal of Medicinal Chemistry 2014 , 85 , 77-86. 85 , 77-86. https://doi.org/10.1016/j.ejmech.2014.07.062

Matthew R. Woodward, David G. Harper, Arkadiy Stolyar, Brent P. Forester, James M. Ellison. Dronabinol for the Treatment of Agitation and Aggressive Behavior in Acutely Hospitalized Severely Demented Patients with Noncognitive Behavioral Symptoms. The American Journal of Geriatric Psychiatry 2014 , 22 (4) , 415-419. 22 (4) , 415-419. https://doi.org/10.1016/j.jagp.2012.11.022

Ester Aso, Isidre Ferrer. Cannabinoids for treatment of Alzheimerâ€™s disease: moving toward the clinic. Frontiers in Pharmacology 2014 , 5 https://doi.org/10.3389/fphar.2014.00037

Kelly P. Owen, Mark E. Sutter, Timothy E. Albertson. Marijuana: Respiratory Tract Effects. Clinical Reviews in Allergy & Immunology 2014 , 46 (1) , 65-81. 46 (1) , 65-81. https://doi.org/10.1007/s12016-013-8374-y

Andrew G. Horti, Vanessa Raymont, Garth E. Terry. PET Imaging of Endocannabinoid System. 2014 ,,, 249-319. ,, 249-319. https://doi.org/10.1007/978-3-642-42014-6_11

Cindy Casteels, Guy Bormans, Koen Van Laere. Brain Imaging of Cannabinoid Receptors. 2014 ,,, 37-79. ,, 37-79. https://doi.org/10.1016/B978-0-12-418677-4.00003-8

Chandrabhan Seniya, Ghulam Jilani Khan, Kuldeep Uchadia. Identification of Potential Herbal Inhibitor of Acetylcholinesterase Associated Alzheimer’s Disorders Using Molecular Docking and Molecular Dynamics Simulation. Biochemistry Research International 2014 , 2014 , 1-7. 2014 , 1-7. https://doi.org/10.1155/2014/705451

R. Ribeiro, F. Yu, J. Wen, A. Vana, Y. Zhang. Therapeutic potential of a novel cannabinoid agent CB52 in the mouse model of experimental autoimmune encephalomyelitis. Neuroscience 2013 , 254 , 427-442. 254 , 427-442. https://doi.org/10.1016/j.neuroscience.2013.09.005

Nazia Maroof, Marie Christine Pardon, David A. Kendall. Endocannabinoid signalling in Alzheimer's disease. Biochemical Society Transactions 2013 , 41 (6) , 1583-1587. 41 (6) , 1583-1587. https://doi.org/10.1042/BST20130140

Christoph Stumm, Christof Hiebel, Regina Hanstein, Martin Purrio, Heike Nagel, Andrea Conrad, Beat Lutz, Christian Behl, Angela B. Clement. Cannabinoid receptor 1 deficiency in a mouse model of Alzheimer's disease leads to enhanced cognitive impairment despite of a reduction in amyloid deposition. Neurobiology of Aging 2013 , 34 (11) , 2574-2584. 34 (11) , 2574-2584. https://doi.org/10.1016/j.neurobiolaging.2013.05.027

Nerea Ferreirós. Recent advances in LC–MS/MS analysis of Δ 9 -tetrahydrocannabinol and its metabolites in biological matrices. Bioanalysis 2013 , 5 (21) , 2713-2731. 5 (21) , 2713-2731. https://doi.org/10.4155/bio.13.218

Rosivaldo Borges, João Batista, Rommel Viana, Ana Baetas, Ednilsom Orestes, Marcieni Andrade, Káthia Honório, Albérico da Silva. Understanding the Molecular Aspects of Tetrahydrocannabinol and Cannabidiol as Antioxidants. Molecules 2013 , 18 (10) , 12663-12674. 18 (10) , 12663-12674. https://doi.org/10.3390/molecules181012663

Jason Barricklow, Matthew Blatnik. 2-Arachidonoylglycerol is a substrate for butyrylcholinesterase: A potential mechanism for extracellular endocannabinoid regulation. Archives of Biochemistry and Biophysics 2013 , 536 (1) , 1-5. 536 (1) , 1-5. https://doi.org/10.1016/j.abb.2013.05.003

Tarek Mohamed, Jacky C.K. Yeung, Maryam S. Vasefi, Michael A. Beazely, Praveen P.N. Rao. Development and evaluation of multifunctional agents for potential treatment of Alzheimer’s disease: Application to a pyrimidine-2,4-diamine template. Bioorganic & Medicinal Chemistry Letters 2012 , 22 (14) , 4707-4712. 22 (14) , 4707-4712. https://doi.org/10.1016/j.bmcl.2012.05.077

Tim Karl, David Cheng, Brett Garner, Jonathon C. Arnold. The therapeutic potential of the endocannabinoid system for Alzheimer's disease. Expert Opinion on Therapeutic Targets 2012 , 16 (4) , 407-420. 16 (4) , 407-420. https://doi.org/10.1517/14728222.2012.671812

Walter J Lukiw. Amyloid beta (Aβ) peptide modulators and other current treatment strategies for Alzheimer’s disease (AD). Expert Opinion on Emerging Drugs 2012 , 17 (1) , 43-60. 17 (1) , 43-60. https://doi.org/10.1517/14728214.2012.672559

Ki-Yeol Yoo, So-Young Park. Terpenoids as Potential Anti-Alzheimer’s Disease Therapeutics. Molecules 2012 , 17 (3) , 3524-3538. 17 (3) , 3524-3538. https://doi.org/10.3390/molecules17033524

Benjamin S. Harvey, Katharina S. Ohlsson, Jesper L.V. Mååg, Ian F. Musgrave, Scott D. Smid. Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro. NeuroToxicology 2012 , 33 (1) , 138-146. 33 (1) , 138-146. https://doi.org/10.1016/j.neuro.2011.12.015

Andrew J. Hill, Claire M. Williams, Benjamin J. Whalley, Gary J. Stephens. Phytocannabinoids as novel therapeutic agents in CNS disorders. Pharmacology & Therapeutics 2012 , 133 (1) , 79-97. 133 (1) , 79-97. https://doi.org/10.1016/j.pharmthera.2011.09.002

Aoife Gowran, Janis Noonan, Veronica A. Campbell. The Multiplicity of Action of Cannabinoids: Implications for Treating Neurodegeneration. CNS Neuroscience & Therapeutics 2011 , 17 (6) , 637-644. 17 (6) , 637-644. https://doi.org/10.1111/j.1755-5949.2010.00195.x

Tarek Mohamed, Jacky C.K. Yeung, Praveen P.N. Rao. Development of 2-substituted-N-(naphth-1-ylmethyl) and N-benzhydrylpyrimidin-4-amines as dual cholinesterase and Aβ-aggregation inhibitors: Synthesis and biological evaluation. Bioorganic & Medicinal Chemistry Letters 2011 , 21 (19) , 5881-5887. 21 (19) , 5881-5887. https://doi.org/10.1016/j.bmcl.2011.07.091

Antoni R. Blaazer, Jos H.M. Lange, Martina A.W. van der Neut, Arie Mulder, Femke S. den Boon, Taco R. Werkman, Chris G. Kruse, Wytse J. Wadman. Novel indole and azaindole (pyrrolopyridine) cannabinoid (CB) receptor agonists: Design, synthesis, structure–activity relationships, physicochemical properties and biological activity. European Journal of Medicinal Chemistry 2011 , 46 (10) , 5086-5098. 46 (10) , 5086-5098. https://doi.org/10.1016/j.ejmech.2011.08.021

Scott A. Wildman, Xiange Zheng, David Sept, Jeffrey T. Auletta, Terrone L. Rosenberry, Garland R. Marshall. Drug-like Leads for Steric Discrimination between Substrate and Inhibitors of Human Acetylcholinesterase. Chemical Biology & Drug Design 2011 , 78 (4) , 495-504. 78 (4) , 495-504. https://doi.org/10.1111/j.1747-0285.2011.01157.x

Ethan B Russo. Taming THC: potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. British Journal of Pharmacology 2011 , 163 (7) , 1344-1364. 163 (7) , 1344-1364. https://doi.org/10.1111/j.1476-5381.2011.01238.x

Joan L. Bottorff, Laura J. L. Bissell, Lynda G. Balneaves, John L. Oliffe, H. Bindy K. Kang, N. Rielle Capler, Jane A. Buxton, Robin K. O’Brien. Health Effects of Using Cannabis for Therapeutic Purposes: A Gender Analysis of Users’ Perspectives. Substance Use & Misuse 2011 , 46 (6) , 769-780. 46 (6) , 769-780. https://doi.org/10.3109/10826084.2010.537732

Tarek Mohamed, Xiaobei Zhao, Lila K. Habib, Jerry Yang, Praveen P.N. Rao. Design, synthesis and structure–activity relationship (SAR) studies of 2,4-disubstituted pyrimidine derivatives: Dual activity as cholinesterase and Aβ-aggregation inhibitors. Bioorganic & Medicinal Chemistry 2011 , 19 (7) , 2269-2281. 19 (7) , 2269-2281. https://doi.org/10.1016/j.bmc.2011.02.030

Sazal Patyar, Ajay Prakash, Bikash Medhi. Dual inhibition: a novel promising pharmacological approach for different disease conditions. Journal of Pharmacy and Pharmacology 2011 , 63 (4) , 459-471. 63 (4) , 459-471. https://doi.org/10.1111/j.2042-7158.2010.01236.x

Kewal K. Jain. Neuroprotection in Alzheimer’s Disease. 2011 ,,, 337-367. ,, 337-367. https://doi.org/10.1007/978-1-61779-049-2_8

Sebastian Walther, Michael Halpern. Cannabinoids and Dementia: A Review of Clinical and Preclinical Data. Pharmaceuticals 2010 , 3 (8) , 2689-2708. 3 (8) , 2689-2708. https://doi.org/10.3390/ph3082689

Paramita Chakrabarty, Pritam Das, Todd E. Golde. Current and Future Therapies for Alzheimer Disease. 2010 ,,, 711-774. ,, 711-774. https://doi.org/10.1002/9780470572702.ch34

Richard Hartman. Actions of Bioactive Phytochemicals in Cell Function and Alzheimer’s Disease Pathology. 2009 ,,https://doi.org/10.1201/9781420073522.ch16

Hozefa Amijee, Jill Madine, David A. Middleton, Andrew J. Doig. Inhibitors of protein aggregation and toxicity. Biochemical Society Transactions 2009 , 37 (4) , 692-696. 37 (4) , 692-696. https://doi.org/10.1042/BST0370692

Sarada Krishnan, Ruth Cairns, Robert Howard, . Cannabinoids for the treatment of dementia. Cochrane Database of Systematic Reviews 2009 , 12 12 https://doi.org/10.1002/14651858.CD007204.pub2

Antonio M. Ferreira, Mathangi Krishnamurthy, Bob M. Moore, David Finkelstein, Donald Bashford. Quantitative structure–activity relationship (QSAR) for a series of novel cannabinoid derivatives using descriptors derived from semi-empirical quantum-chemical calculations. Bioorganic & Medicinal Chemistry 2009 , 17 (6) , 2598-2606. 17 (6) , 2598-2606. https://doi.org/10.1016/j.bmc.2008.11.059

José Martínez Orgado, Javier Fernández-Ruiz, Julián Romero. The endocannabinoid system in neuropathological states. International Review of Psychiatry 2009 , 21 (2) , 172-180. 21 (2) , 172-180. https://doi.org/10.1080/09540260902782828

Sarada Krishnan, Ruth Cairns, Robert Howard, . Cannabinoids for the treatment of dementia. 2008 ,,https://doi.org/10.1002/14651858.CD007204

Walter J Lukiw. Emerging amyloid beta (Ab) peptide modulators for the treatment of Alzheimer's disease (AD). Expert Opinion on Emerging Drugs 2008 , 13 (2) , 255-271. 13 (2) , 255-271. https://doi.org/10.1517/14728214.13.2.255

Michael J. Passmore. The cannabinoid receptor agonist nabilone for the treatment of dementia-related agitation. International Journal of Geriatric Psychiatry 2008 , 23 (1) , 116-117. 23 (1) , 116-117. https://doi.org/10.1002/gps.1828

María L. de Ceballos. Endocannabinoids in Alzheimer's Disease. 2008 ,,, 395-405. ,, 395-405. https://doi.org/10.1007/978-0-387-74349-3_19

Dae-Hyung Lee, Ji-Su Lee, Sung-Hun Yi, Jong-Soo Lee. Production of the Acetylcholinesterase Inhibitor from Yarrowia lipolytica S-3. Mycobiology 2008 , 36 (2) , 102. 36 (2) , 102. https://doi.org/10.4489/MYCO.2008.36.2.102

Koen Van Laere. In vivo imaging of the endocannabinoid system: a novel window to a central modulatory mechanism in humans. European Journal of Nuclear Medicine and Molecular Imaging 2007 , 34 (11) , 1719-1726. 34 (11) , 1719-1726. https://doi.org/10.1007/s00259-007-0505-3

V A Campbell, A Gowran. Alzheimer's disease; taking the edge off with cannabinoids?. British Journal of Pharmacology 2007 , 152 (5) , 655-662. 152 (5) , 655-662. https://doi.org/10.1038/sj.bjp.0707446

Cristina Benito, Estefanía Núñez, María Ruth Pazos, Rosa María Tolón, Julián Romero. The Endocannabinoid System and Alzheimer’s Disease. Molecular Neurobiology 2007 , 36 (1) , 75-81. 36 (1) , 75-81. https://doi.org/10.1007/s12035-007-8006-8

Raul Gonzalez. Acute and Non-acute Effects of Cannabis on Brain Functioning and Neuropsychological Performance. Neuropsychology Review 2007 , 17 (3) , 347-361. 17 (3) , 347-361. https://doi.org/10.1007/s11065-007-9036-8

Ethan B. Russo. History of Cannabis and Its Preparations in Saga, Science, and Sobriquet. Chemistry & Biodiversity 2007 , 4 (8) , 1614-1648. 4 (8) , 1614-1648. https://doi.org/10.1002/cbdv.200790144