One hallmark of the aging retina is the accumulation of sub-retinal pigment epithelium (RPE) deposits of proteins and lipids. If clumped together, they’re known as drusen, if diffuse, they’re referred to as basal laminar deposits. But irrespective of their nomenclature, they’re believed to be involved in the pathogenesis of age-related macular degeneration – (AMD) as impaired metabolic exchange between the choroid and the retina, ultimately damages the latter structure. But what initiates their formation? What keeps them in Bruch’s membrane? A team of researchers based in the US, UK and Germany may have the answer: hydroxyapatite (bone mineral) spherules (1).

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About the Author

Roisin McGuigan

I have an extensive academic background in the life sciences, having studied forensic biology and human medical genetics in my time at Strathclyde and Glasgow Universities. My research, data presentation and bioinformatics skills plus my ‘wet lab’ experience have been a superb grounding for my role as a deputy editor at Texere Publishing. The job allows me to utilize my hard-learned academic skills and experience in my current position within an exciting and contemporary publishing company.