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Ryan Giggs - 145 appearances

He's made more appearances for Manchester United than anyone else, so it's little surprise the Welshman has also made the most appearances for the Red Devils in Europe. Of his 145 appearances, the two that will stand out will be the final victories - the first of which came at the Nou Camp against Bayern Munich in 1999 and the second in Moscow against Chelsea, in which he scored United's final penalty in the shoot-out.

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