Moscow (CNN) Russian Prime Minister Mikhail Mishustin has tested positive for Covid-19 and will self-isolate.

Mishustin confirmed his test results in a videoconference with President Vladimir Putin, and nominated his deputy to take over for him as acting Prime Minister.

"It just became known that the coronavirus tests I took came back positive, so I must oblige by the self-isolation rules and it's mandatory [that I do that] for the safety of my colleagues," Mishustin said in a segment aired on Russia 24 state channel.

Putin signed a decree appointing Andrey Belousov to the role on an acting basis, following Mishustin's recommendation.

Mishustin's diagnosis makes him the most high-profile political figure in Russia to contract the coronavirus.

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