Dihydrotestosterone (DHT) is a biologically active metabolite of testosterone. It is formed primarily in the prostate gland, testes, hair follicles, and adrenal glands. Scientific research has discovered that DHT is the primary contributing factor in male-pattern baldness. DHT also plays a role in the development or exacerbation of benign prostatic hyperplasia (BPH) and prostate cancer.

Recent medical research in the area of prostate health has involved the development of drugs and supplements, which will block or at least inhibit the production of DHT. There are a number of drugs on the market that act as DHT blockers, including finasteride (sold under the names Proscar for BPH and Propecia for androgenic alopecia) and dutasteride (sold under the name Avodart). There is also a natural DHT blocker Saw Palmetto, which has shown promise in the treatment of BHP and hair loss.