Rand Paul Randal (Rand) Howard PaulSecond GOP senator to quarantine after exposure to coronavirus GOP senator to quarantine after coronavirus exposure The Hill's Morning Report - Sponsored by National Industries for the Blind - Trump seeks to flip 'Rage' narrative; Dems block COVID-19 bill MORE and Marco Rubio Marco Antonio RubioFlorida senators pushing to keep Daylight Savings Time during pandemic Hillicon Valley: DOJ indicts Chinese, Malaysian hackers accused of targeting over 100 organizations | GOP senators raise concerns over Oracle-TikTok deal | QAnon awareness jumps in new poll Intelligence chief says Congress will get some in-person election security briefings MORE piled onto Ted Cruz Rafael (Ted) Edward CruzLoeffler calls for hearing in wake of Netflix's 'Cuties' Health care in the crosshairs with new Trump Supreme Court list 'Parks and Rec' cast members hosting special reunion to raise money for Wisconsin Democrats MORE at Thursday night’s GOP presidential debate, accusing him of lying about his opposition on immigration to seem more conservative.

“This is the lie that Ted’s campaign is built on, and Rand touched upon it, that he's the most conservative guy and everyone else is a RINO,” Florida Sen. Rubio said, using the acronym for “Republican in Name Only.”

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“The truth is Ted, throughout this campaign, you’ve been willing to say and do anything in order to get votes.”

Rubio also accused Cruz of helping design former President George W. Bush’s immigration policy, which provided a path to legal status for those who entered the country illegally.

Rubio's barbs followed those from Kentucky Sen. Paul, who called the Texas senator the “king” of accusing others of not really being against amnesty.

“That's a falseness, and that’s an authenticity problem, that everybody he knows is not as perfect as him because we are all for amnesty,” he said.

“I was for legalization ... so was Ted, but now he says it wasn't so. That's not true.”

The comments came after Fox News showed a series of clips from the 2013 immigration negotiations in the Senate.

The clips showed Cruz backing amendments to an immigration reform bill that provided a path to legal status.

In the clips, Cruz said that the bill would pass if his amendments were passed. He also said he hoped to find a middle ground to "allow for those 11 million people here illegally a legal status with citizenship off the table."

Fox News’s Megyn Kelly, after the clips were shown, said that if Cruz was acting, it was a good performance.

Cruz claims, though, that those amendments were meant as a "poison pill" to sink the entire bill. He also noted that Sen. Jeff Sessions (R-Ala.), a strong critic of immigration reform efforts, was on his side in the fight.

After Paul's barb, Cruz noted that Rubio supported that 2013 bill that provided a pathway to citizenship.

“When that battle was waged, my friend Sen. Rubio chose to stand with Barack Obama, Harry Reid, and Chuck Schumer to support amnesty,” he said of the Democrats.

“I stood alongside Jeff Sessions and Steve King and we led the fight against amnesty,” he added.

Rep. King (Iowa), is backing Cruz for president and is also known as a loud opponent of immigration reform.