The 27-year-old Bethel-Thompson finished the 2015 season on the San Francisco 49ers' practice squad. He has never appeared in a regular season game. In the 2015 preseason with Miami, Bethel-Thompson completed 61.8 percent of his pass attempts for 244 yards. He originally entered the NFL as a rookie free agent with the 49ers in 2011. He spent time with Miami in 2011 and the Vikings in 2012 before being re-acquired by the 49ers in 2013. He finished that season on the 49ers' practice squad. In 2014, Bethel-Thompson was with the New England, Minnesota and Miami practice squads. In addition to his NFL career, Bethel-Thompson has also had stints in the Arena Football League. A San Francisco native, the 6-3, 236-pound Bethel-Thompson transferred from UCLA to Sacramento State and played the final three years of college football there.