Per ESPN NFL Insider Adam Schefter, J Jones likely needs wrist surgery and is out indefinitely. R. Shazier has sprained knee. Will have MRI. — Scott Brown (@ScottBrown_ESPN) September 22, 2014

Although the Pittsburgh Steelers had remained a very healthy unit through the first two weeks of NFL competition, that trend ended when the Steelers saw three defensive starters leave the game against the Carolina Panthers unable to return.

Ike Taylor's injury was the most obvious and the most grotesque, when we saw Taylor's arm broken by a Lawrence Timmons tackle in the second half of the game. But injuries to outside linebacker Jarvis Jones and rookie inside linebacker Ryan Shazier were much less distinctive.

As reported via Twitter by ESPN.com's Scott Brown, Ryan Shazier has a sprained knee and will require an MRI to determine the severity of the injury. Shazier dealt with a knee injury in training camp that kept him out of competition for weeks, but Shazier has shown no signs of any lingering injury throughout the first two weeks of play.

Sean Spence filled in for Shazier for the remainder of the second half, and was credited with four tackles.

Jarvis Jones left the game with a wrist injury, and it's being reported his injury will require surgery and will have him out of the lineup indefinitely. Jones had been having a solid game, sacking the quarterback once and getting multiple pressures before being injured. That sack was his second in three games.

Arthur Moats replaced Jones at outside linebacker and registered a sack and two tackles.

The Steelers have solid depth at the linebacker position but, if Shazier and Jones miss significant playing time, the team may be forced to make a personnel move to help at that position.

Mike Tomlin's press conference is Tuesday at 12:00 p.m. ET where he will provide more detailed information and a timeline for any injury the team sustained in Sunday night's victory.