Ohio State junior quarterback Braxton Miller left the field Saturday after spraining his left knee and Buckeyes coach Urban Meyer thinks the junior could return for next week's game at California.

With the Buckeyes leading San Diego State, 7-0, Miller took off running on fourth-and-1, picked up the first down but. His helmet also was knocked off during the tackle.

"We had a long discussion on the sideline," Meyer said. "I think he could have (returned). But the things that make him dangerous are his wheels and I don't think it would have been (the same). So we decided it was best not to."

Ohio State went on to win 42-7.

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Kenny Guiton replaced Miller at quarterback and was sharp. He completed 19 of 28 passes for 152 yards, two touchdowns and an interception. He also ran for 83 yards on nine carries, including a 44-yard TD run.

Miller is considered one of the Heisman Trophy frontrunners in 2013 after leading Ohio State to an undefeated season last year. In the season-opening win against Buffalo, Miller threw for 178 yards and two TDs and ran for another 77 yards.

In 2012, Miller ran for 1,271 yards and 13 scores and passed for 2,039 yards and another 17 touchdowns.