NEW YORK—You knew things were going wrong for Jo-Jo Reyes several minutes before he took the mound.

Yunel Escobar started Wednesday afternoon’s game against the Yankees with a first-pitch triple. The next three batters, including Jose Bautista, couldn’t budge him.

Reyes, seeking to avoid tying a major-league record for most consecutive starts without a win, couldn’t help himself either.

Over three innings, he allowed five runs, including a pair of two-run homers, one to Andruw Jones and the other to Mark Teixeira. He left the game before the start of the fourth. At the time, the Jays were losing 5-0.

Jones would add another two-run homer off reliever Luis Perez as the Yankees breezed to a 7-3 win.

Reyes (0-4) now owns part of one of pitching’s most depressing records. Only he and Matt Keough, formerly of the Oakland A’s, have gone 28 starts without a win. Keough set the mark in 1978-79.

Reyes last won a game on June 13, 2008 as a member of the Atlanta Braves.

He will attempt to avoid owning history when he faces the best team in the American League, the Cleveland Indians, at the Rogers Centre on Monday.