A prominent Queensland barrister has lost his unusual legal challenge over a $146 speeding fine in the state's highest court.

Tony Morris, QC, argued he shouldn't be found liable for the infringement because he wasn't behind the wheel when his Volvo wagon was last year snapped travelling at 57km/h in a 50km/h zone at St Lucia, in Brisbane's inner-west.

Barrister Tony Morris has lost his unusual legal challenge over a $146 ticket.

His legal challenge potentially would have helped countless Queensland motorists get out of speeding fines, but it was lost in the Court of Appeal on Tuesday.

Mr Morris previously said he had no problem with paying the fine, and the case was about the fairness of a law that made every Queensland motorist liable when their vehicle was used to commit an offence.