All good things must come to an end.

For Nashville SC, their 2-1 loss to Louisville City FC in the U.S. Open Cup Wednesday meant the end of two things. The Boys in Gold have not only been eliminated in the round of 16 of the Cup, but they also see their unbeaten streak in all competitions come an end at 11.

Nashville rolled out the same formation it used Saturday against North Carolina FC, with just a couple of changes. Late-winner savant Ropapa Mensah came on to start up top, with Lebo Moloto hanging back behind him. Michael Reed and Bolu Akinyode once again controlled the middle of the park, with Ish Jome and Matt LaGrassa out wide. London Woodberry came in and played in the back, which was the only change on the defense that has only allowed two goals in its past five contests coming in.

Louisville, meanwhile, was facing a plethora of injuries. One of them included top goal-scorer Cameron Lancaster, who was ruled doubtful before the contest.

The Boys in Gold had a rough go at trying to crack the Louisville defense, mustering only one shot the entire first half.

Louisville broke the deadlock in the 24th minute. After conceding a corner, the Bourbon Boys elected to play the set piece short to Oscar Jimenez. Jimenez took a couple of dribbles before whipping in a low cross to a crowd of players. In that crowd was Paco Craig making a near post run, where he blasted it past Pickens for the 1-0 lead.

On if he thinks his team was hesitant to attack in the first half. pic.twitter.com/sNpoGNJkST — Golden Goal (@GoldenGoalNash) June 21, 2018

The Bourbon Boys doubled their lead in the 58th minute. Paolo DelPiccolo found the ball at his feet after what looked like an attempted shot from George Davis right inside the six-yard box. DelPiccolo was able to tuck it into the bottom part of the goal to make it 2-0.

Nashville was able to pull one back in the 68th minute when London Woodberry swung in a cross from the right side that met the head of Matt LaGrassa making a near post run right near the six-yard box.

Although there were plenty of chances in front of net, including another way-too-close Bradley Bourgeois header on a cross that was inches away, it just wasn’t meant to be for Nashville.

And what his team needs to do to respond to their first loss in 11 games. pic.twitter.com/tznN8Q9R8b — Golden Goal (@GoldenGoalNash) June 21, 2018

Louisville now moves on to the quarterfinal to take on Chicago Fire. Nashville returns to action in the USL Tuesday against Indy Eleven at First Tennessee Park.