That attitude could mean grim consequences for black transgender people.

Some black men who knowingly engage in relationships with transgender women might become ashamed when others find out, turning violent against their partners, advocates said. Ms. St. James recalled being sexually assaulted in the streets of Flatbush, Brooklyn, by an acquaintance. When she asked passers-by for help, her attacker told them that she was transgender, and the would-be helpers instead mocked her.

Although the raw numbers are small, estimates suggest that transgender people are killed at a much higher rate than the general population. While the chance of a young adult being murdered is 1 in 12,000, that probability increases to 1 in 2,600 for young, black transgender women, according to an analysis by the news organization Mic. At least 111 people who were transgender or did not identify with a gender were killed between 2010 and 2016, the report said, with nearly three in four of them being black women or people who presented as feminine.

Lil Duval’s comments on the radio show, which aired on July 28, spoke to these grim statistics. The morning show on Power 105.1 — featuring the hosts DJ Envy, Angela Yee and Charlamagne Tha God — is known for its edgy interviews with celebrities, who have ranged from rappers to Hillary Clinton, who went on the show just weeks before last year’s election.

The controversy with the Duval interview started when one of the hosts asked him what he thought of President Trump’s proposed ban on transgender people serving in the military. When he joked that transgender women were actually men, the hosts laughed along, but they quickly corrected him when he referred to transgender people using a derogatory term. But when DJ Envy asked Lil Duval what he would do if a woman he had sex with later said she was transgender, he responded, “This might sound messed up and I don’t care: She dying.”

The hosts quickly told him that killing a transgender person was a hate crime and that he could not do that. But Lil Duval continued to make jokes and said it was about manipulation and taking away his choice.

Charlamagne Tha God, the show’s most popular host, agreed with that point, saying that by not disclosing she is transgender, a woman is “taking away a person’s power of choice,” and he added that “you should go to jail or something.”