The stellar ensemble cast for Murder on the Orient Express includes Kenneth Branagh, Johnny Depp, Michelle Pfeiffer, Daisy Ridley, Judi Dench, Lucy Boynton, Tom Bateman, Derek Jacobi, Manuel Garcia Rulfo, Leslie Odom Jr, Sergei Polunin, Josh Gad, Penelope Cruz, Marwan Kenzari, Willem Dafoe and Olivia Colman. Discover more about each cast member below.