Donald Trump has courted controversy once again - this time by mocking an overweight man at a rally in Worcester, Massachusetts.

The Republican presidential hopeful was speaking at an event on Wednesday night when he was interrupted several times by protesters.

While Trump usually brushes off interruptions, he responded to one man with an insult.

'It's amazing. I mentioned food stamps and that guy who's seriously overweight went crazy,' Trump said in response.

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Controversial: Donald Trump has courted controversy by mocking an overweight man at a rally in Worcester

The man shouted as he was escorted out by police at the rally on Wednesday night, along with other protesters

At that point, the man and other protesters were escorted out by police.

Earlier another protester shouted, 'You're a racist!' before being escorted out.

Trump remarked to the crowd: 'Isn't a Trump rally much more exciting than these other guys?'

He added: 'We had 12,000 people, and [the media] are gona take three people and say 'Oh, the protests were unbelievable'.

'Three people! They weren't even in a group, because who the hell wants to be with a guy like that, to be in a group? Seriously. Who wants to be with him? Nobody. Nobody. Nobody will have him. Nobody.'

Before the rally, Trump, who has said he believes the U.S. will have to close some mosques because of radical activity, also predicted he'll win with Muslim voters.

Before the rally, Trump, who has said he believes the U.S. will have to close some mosques because of radical activity, also predicted he'll win with Muslim voters

'I'm going to do great with the Muslims,' said Trump. 'They understand what I'm saying... We're talking about safety. We're talking about security. We need it.'

Trump also continued to criticize President Barack Obama's response to the attacks in Paris, blaming American actions for destabilizing the Middle East and fueling the Islamic State group's rise.

He has repeatedly criticized Democrats, including the president, for avoiding the term 'radical Islamic terrorism' — a phrase they say unfairly criticizes all Muslims.