Clemson All-American defensive tackle Dexter Lawrence and two other players have tested positive for Ostarine ahead of the Tigers' appearance in the College Football Playoff, head coach Dabo Swinney confirmed on Monday.

Lawrence’s test shows “trace amounts of ostarine,” according to The Greenville News, but a B Sample could potentially clear him and teammates Zach Giella and Braden Galloway on Wednesday. Swinney said Clemson athletic director Dan Radakovich was told last week by the NCAA that three players failed a drug test with a “slither of ostarine.”

Ostarine, in short, helps to build muscle and cut fat, and is a substance on the NCAA's banned list under the category of "Anabolic Agents" on Page 2 of the updated guidelines.

Here's some of the national reaction following potentially devastating news for Clemson ahead of Saturday's Cotton Bowl vs. Notre Dame: