HOMICIDE detectives and the family of missing woman Sarah Spiers have made another plea for information into her disappearance and suspected murder 21 years ago, in the hope someone will come forward.

Cold case Homicide Squad detectives released a photo this morning of a vehicle they think could be involved in some way and could help them in their investigation.

Ms Spiers disappeared after a night out with friends in Claremont on January 26, 1996 after calling a taxi from a telephone box on the corner of Stirling Road and Stirling Highway at around 2am, but when the taxi arrived she was nowhere to be seen.

Her body has never been found.

Detective Superintendent Rod Wilde from the special crime division said despite the significant passage of time, it was still possible the vehicle could assist police.

“It is a new line of inquiry we’d like to finalise,” he said.

“We are aware this car was deregistered in 2008, but from that time onwards it is unclear what happened to it.

“It may have been wrecked or abandoned or could still be in use on a rural property.”

The vehicle police are looking for is a 1992 Toyota Camry station wagon and had a Vehicle Identification Number 6T172SV2109318479.

He said even if the vehicle was in pieces, police would still like to examine it.

Don Spiers issued a release on the new line of inquiry, urging anyone with information to contact police.

“We have been kept informed by the police on the status of the investigation. We do not want to comment publicly about today’s appeal, apart from urging anyone who knows anything about this car, or where it might be, to please contact the police,” he said.

Anyone with information is asked to call Crime Stoppers on 1800 333 000.