“People say to me all the time well, 'Do you think she might run for office sometime?'” David Axelrod, chief strategist for Obama’s 2008 and 2012 presidential campaigns, told conservative talk radio host Hugh Hewitt. “I would bet everything that I own against that prospect.”

But Axelrod said the first lady’s longstanding dislike of partisan politics all but rules out a future political run of her own.

“She was a reluctant conscript to politics,” he said of Obama. “I mean, when Michelle, you know, she had her own sort of professional life, and she was very committed, as she is now, to the kids.”

He also ruled out the possibility of Obama, who previously worked as a lawyer, seeking a judicial appointment.

The operative said Obama “gave up a lot” to boost her husband’s bids for the White House and is campaigning for Clinton not because she is “someone who loves politics,” but “because she feels passionately about the choice here.”

The first lady is “going to be very happy to get her life back when this is over,” he said.

Axelrod predicted she will “recede a little bit from the public eye" and will be "trying to help on the issues that she cares about.”

Obama's campaign appearances this year have stoked speculation about her political future.

Clinton’s campaign dispatched Obama to Arizona on Thursday, believing that she could help move the reliable red state back into the Democrats’ column for the first time since 1996.

Some Illinois Democrats are hoping the first lady has a change of heart about politics.