But amid the concern, that crisis began to generate something else: a raft of innovative new methods for dealing with the accumulation of information. These included early plans for public libraries, the first universal bibliographies that tried to list all books ever written, the first advice books on how to take notes, and encyclopedic compilations larger and more broadly diffused than ever before. Detailed outlines and alphabetical indexes let readers consult books without reading them through, and the makers of large books experimented with slips of paper for cutting and pasting information from manuscripts and printed matter — a technique that, centuries later, would become essential to modern word processing.

But is it really so novel? Human history is a long process of accumulating information, especially once writing made it possible to record texts and preserve them beyond the capacity of our memories. And if we look closely, we can find a striking parallel to our own time: what Western Europe experienced in the wake of Gutenberg’s invention of printing in the 15th century, when thousands upon thousands of books began flooding the market, generating millions of copies for sale. The literate classes experienced exactly the kind of overload we feel today — suddenly, there were far more books than any single person could master, and no end in sight. Scholars, at first delighted with the new access to information, began to despair. “Is there anywhere on earth exempt from these swarms of new books?” asked Erasmus, the great humanist of the early 16th century.

Beneath all this concern lies the sense that humanity is experiencing an unprecedented change — that modern technology is creating a problem that our culture and even our brains are ill equipped to handle. We stand on the brink of a future that no one can ever have experienced before.

Many feel the situation has reached crisis proportions. In the academic world, critics have begun to argue that universities are producing and distributing more knowledge than we can actually use. In the recent best-selling book “The Shallows,” Nicholas Carr worries that the flood of digital information is changing not only our habits, but even our mental capacities: Forced to scan and skim to keep up, we are losing our abilities to pay sustained attention, reflect deeply, or remember what we’ve learned.

Worry about information overload has become one of the drumbeats of our time. The world’s books are being digitized, online magazines and newspapers and academic papers are steadily augmented by an endless stream of blog posts and Twitter feeds; and the gadgets to keep us participating in the digital deluge are more numerous and sophisticated. The total amount of information created on the world’s electronic devices is expected to surpass the zettabyte mark this year (a barely conceivable 1 with 21 zeroes after it).

To confront this new challenge, printers, scholars, and compilers began to develop novel ways to manage all these texts — tools that listed, sorted under subject headings, summarized, and selected from all those books that no one person could master. Note-taking was one solution, which the humanist pedagogues advocated alongside their teaching of ancient rhetoric. But not everyone followed their advice to take notes from everything they read throughout their lives, and for those who didn’t, new kinds of reference books offered a ready-made version — collections of best bits that could be consulted using sophisticated indexes and tables of contents.

More pragmatically, a contemporary jurist complained that the “multitude of volumes” also made it hard to find the books one needed at the bookstore. Happy the illiterate, exclaimed one Italian editor (in the preface to one of his many publications), to be spared the malediction of books!

But around 1500, humanist scholars began to bemoan new problems: Printers in search of profit, they complained, rushed to print manuscripts without attention to the quality of the text, and the sheer mass of new books was distracting readers from the focus on the ancient authors most worthy of attention. Printers “fill the world with pamphlets and books that are foolish, ignorant, malignant, libelous, mad, impious and subversive; and such is the flood that even things that might have done some good lose all their goodness,” wrote Erasmus in the early 16th century, in the kind of tirade that might seem familiar to anyone exhausted by what they find online today.

The printing press changed that. First developed around 1453, the new technology invented by Gutenberg had moved beyond the experimental phase by 1480 and spread to some two dozen major urban centers, with many other short-lived presses in operation. Contemporaries at first raved about the great speed with which books could be printed, and also about the drop in price — by 80 percent on one contemporary’s estimate in 1468.

But what happened in the Renaissance was, like digital technology in our own time, transformative. It took overload to an entirely new order of magnitude. Up to this point, every existing book had been copied by hand — a task that could easily take one copyist a year or more. Books were expensive commodities, most often produced on commission and paid for in advance. The great medieval libraries accumulated manuscripts by the hundreds, but few people ever had access to that many books.

Complaints about information overload, usually couched in terms of the overabundance of books, have a long history — reaching back to Ecclesiastes 12:12 (“of making books there is no end,” probably from the 4th or 3d century BC). The ancient moralist Seneca complained that “the abundance of books is distraction” in the 1st century AD, and there have been other info-booms from time to time — the building of the Library of Alexandria in the 3d century BC, or the development of newspapers starting in the 18th century.

To understand how these earlier generations coped with this flood of information is to help us appreciate the power of human ingenuity to take an inhuman-seeming problem and turn it to productive use — and even, sometimes, to exploit the aspects that seem most overwhelming at the time.

In the Middle Ages, theologians and jurists had developed biblical concordances and alphabetized subject headings to manage their canonical texts, and with the explosion of printed books these tools were adapted to books for more general audiences. They were intended not just for specialists, but for busy rulers and merchants, preachers, teachers, and students. Printed reference books made a broad range of readers familiar with the use of alphabetical order and indexes. Printing also encouraged a trend toward ever larger reference books as each edition tried to lure more buyers by offering something of interest to everyone, or at least everyone who could read Latin.

One of these was the “florilegium,” a book gathering memorable quotations (or “flowers”) from respected authorities of many kinds — religious writers, philosophers, poets, and orators. These had existed before as slim handmade collections but now grew into large printed volumes, sorted under a wide range of subject headings so that readers could find and use quotations on any topic on which they were speaking or writing. One spectacularly large reference book, the “Theatrum humanae vitae” (the “Theater of Human Life”), published in 1565, gathered examples of human behavior both good and bad from all periods of history, providing instructive ethical models and supporting evidence for every imaginable argument. These books themselves are no longer familiar to us (though “Bartlett’s Familiar Quotations” is a florilegium by another name), but the basic notion of selecting, summarizing, and categorizing information from multiple sources has grown only more important, underlying everything from Reader’s Digest to the most sophisticated online aggregators.

The larger printed books became, the more they needed to offer guidance through their own texts. The tables of contents and alphabetical indexes developed by printers and authors to accompany them are still recognizable today. Other devices we would find bewildering: Some books came with diagrams of topics and subtopics in a hierarchical cascade of squiggly brackets that could sprawl over multiple pages. The charts in the “Theatrum humanae vitae” were so complex that they elicited a rare case of explicit feedback — a complaint from one early 17th century professor who found them useless and relied instead on the multiple alphabetical indexes also supplied in the work. More effective to modern eyes, though not as widespread, were tables of contents that outlined layers of subdivisions with successive indentations, as a PowerPoint slide might today (but without the bullet points).