From Anton Nilsson writing at the Daily Mail:

Hillary Clinton raised eyebrows Thursday when she quipped that Donald Trump has gone ‘off the reservation’ in reference to his frequent personal attacks.

The Democratic presidential candidate made the remark in an interview with CNN’s Jake Tapper.

Clinton was asked whether she felt she learned anything about how to deal with Trump’s offensive comments by watching the reactions of Trump’s republican opponents.

“I have a lot of experience dealing with men who sometimes get off the reservation in the way they behave and how they speak,” Clinton responded, hesitating slightly before pronouncing the word ‘reservation.’