Niners defensive tackle Ray McDonald was arrested on suspicion of felony domestic violence early Sunday, San Jose police officials said.

Officers were called around 2:45 a.m. to the 2500 block of Bentley Ridge Drive, a home in San Jose’s upscale Silver Creek neighborhood, said police spokeswoman Sgt. Heather Randol. After a brief investigation by police, McDonald, 29, was taken into custody without incident and booked into the Santa Clara County Jail on $25,000 bail.

Authorities would not elaborate on the circumstances leading to the arrest, but in domestic violence cases, the victim is a spouse, a person in a dating relationship, or a person cohabitating with the suspect, Randol said.

“The 49ers organization is aware of the recent reports regarding Ray McDonald and we take such matters seriously. As we continue to gather the facts, we will reserve further comment,” 49ers general manager Trent Baalke said in a statement Sunday.

McDonald is due in court Sept. 15 at 1:30 p.m.

In 2010, McDonald was arrested for driving under the influence in San Mateo County.

This week, NFL commissioner Roger Goodell instituted harsher penalties for all league employees involved in assault, battery, domestic violence or sexual assault. First-time offenders will receive a six-game suspension. A second offense will result in a lifetime ban. Goodell adopted the harsher penalties after he suspended Ravens running back Ray Rice for two games in July for knocking his then-fiancee unconscious, a punishment Goodell acknowledged was too lenient.

McDonald, 29, who has started 45 of 48 games since 2011, is an integral part of a defense that will open the season without a pair of All-Pro linebackers in Aldon Smith and NaVarro Bowman.

On Friday, Smith was suspended for nine games for violations of the NFL’s personal-conduct policy and substance-abuse policy. Bowman is on the physically unable to perform list with a knee injury and will miss at least the first six games.

The 49ers were roundly criticized in September when they allowed Smith to play every defensive snap in a loss to the Colts two days after he was arrested for his second DUI. Smith checked himself into a rehabilitation facility and missed the next five games.

McDonald is the 10th 49ers player to be arrested in the past 32 months. Since 2012, the 49ers lead the league in player arrests, according to a San Diego Union-Tribune database, which tracks NFL arrests.

Former 49ers safety Donte Whitner has said head coach Jim Harbaugh has told his players violence against women will not be tolerated.

“He said that we can do anything in the world and we can come and talk to him and he’ll forgive us except put our hands on women,” Whitner said in 2012. “If you put your hand on a woman, then you’re done in his book.”

Eric Branch and Evan Sernoffsky are a San Francisco Chronicle staff writers. E-mail: ebranch@sfchronicle.com, esernoffsky@sfchronicle.com Twitter: @Eric_Branch, @EvanSernoffsky