Serving both God and money has long been an aim of fund companies that exclude “sin stocks” of companies dealing in tobacco, guns, gambling and the like in their investments.

Now, two new exchange traded funds offer a conservative evangelical — what is called “biblically responsible” — tilt to that investing approach. The funds explicitly say in their regulatory filing that they will avoid buying shares in companies that have “any degree of participation in activities that do not align with biblical values,” including what they call the lesbian, gay, bisexual and transgender “lifestyle.”

The approach is squarely at odds with that of nearly all of corporate America.

Ninety-two percent of the Fortune 500 companies include “sexual orientation” in their nondiscrimination policies and 82 percent include “gender identity.” For the first time, half of Fortune 500 companies offer transgender-inclusive health care benefits, including for surgical procedures.

“There are millions of people, including people of faith, for whom discrimination is not a biblical value,” said Mark Snyder, the director of communications for the Equality Federation, a national advocacy group. “Businesses have been leading the fight for full equality over the last few years. L.G.B.T. people are part of the fabric of our nation. We have families, we go to work, we simply wish to be treated equally.”