Charlie Sheen‘s manager Mark Burg has responded to Jenny McCarthy‘s concern over the actor’s recent announcement that he has HIV.

The actress, who guest starred alongside Sheen on “Two and a Half Men,” blasted the actor on her SiriusXM radio show on Wednesday for not disclosing his diagnosis sooner, especially to TV love interests.

Burg tried to ease McCarthy’s personal concerns on Thursday and told People, “Charlie was infected long after he left ‘Two and a Half Men’ and long after he worked with Jenny.”

Also Read: Charlie Sheen's HIV Was Joked About in Sony Emails

“Now being on ‘Two and a Half Men’ myself, I feel like in playing a love interest, you would think there would be some type of, I don’t want to say criminal issue, but I don’t even know how to feel about that,” she said on her show, “Dirty, Sexy, Funny.”

“If I have to be upfront about a herpe how could you not be upfront about HIV?” she marveled about the 50-year-old sitcom star. “I look back and I’m like, ‘OK, that would have been some valuable information.’ I mean look how many people have played his love interest on the show.”

McCarthy played Sheen’s love interest for eight episodes of “Two and a Half Men.” Sheen was on the show from 2003 to 2011 before he was replaced by Ashton Kutcher, and Sheen has maintained that he wasn’t diagnosed with HIV until 2011, after the show concluded for him.

Also Read: Jenny McCarthy Blasts Charlie Sheen Over Belated HIV Revelation: 'How Could You Not Be Upfront?'

Notorious Hollywood playboy Sheen went public with his health condition in an interview with Matt Lauer on NBC’s “Today” on Tuesday, saying that HIV is a “hard three letters to absorb … It’s a turning point in one’s life.”