Neil deGrasse Tyson and (from L-R) Eugene Mirman, Alondra Nelson, Clive Thompson on the set of StarTalk, premiering in April on National Geographic Channel.

NEW YORK — "StarTalk," the first-ever science-themed late-night talk show — hosted by superstar scientist Neil deGrasse Tyson — premieres tonight (April 20) on the National Geographic Channel, and viewers can expect a fantastically space-centric viewing experience.

Based on Tyson's long-running radio show of the same name, "StarTalk" is a combination of science, comedy and pop culture. Last week, at the American Museum of Natural History (AMNH) in New York (where portions of the show are filmed), a small group of invitees had the chance to watch the first of the series' 10 episodes. The episode centers around an interview with "Star Trek" alumni George Takei.

"'StarTalk' is a three-strand braid, between science, humor and pop culture," Tyson said at the event. "And that braid is an important recipe for how we are delivering science to the public." [Neil deGrasse Tyson Talks "StarTalk" on TV with Space.com]

Each episode of the show begins with Tyson sitting down with one or two co-hosts at the AMNH's Rose Center for Earth and Space. Tyson and his guests discuss the topic chosen for that episode, and show clips from a pretaped interview with another guest.

The theme of the first episode is "Star Trek," and Tyson's guests at the Rose Center are comedian Leighann Lord, and Charles Liu, an astrophysicist at the AMNH and the College of Staten Island, both of whom are big fans of the "Star Trek" franchise. The trio discussed clips from the show's primary interview, which was pretaped, with actor and activist George Takei, best known for playing Sulu in the original "Star Trek" series.

Both Lord and Liu shared their "Star Trek" wisdom with Tyson, who admits he is not a fan of the iconic series. The interview with Takei and subsequent discussion among the three hosts cover many 'Trek'-related topics, ranging from Takei's story about auditioning for the show, to the science behind the "warp drive" used in the "Star Trek" universe that allows spaceships to travel faster than the speed of light.

But the conversation also veered into more somber territory when Tyson asked Takei about the time he and his family spent in a Japanese internment camp during World War II. The co-hosts then discussed how "Star Trek" broke boundaries of race and gender in the 1960s, and what scientists understand about the underlying biology of race.

The episode wrapped up with a short pretaped segment by Bill Nye the Science Guy, who discussed the connection between technology and civil rights. One of Nye's pretaped segments will be featured in each episode, according to a statement from the National Geographic Channel.

The National Geographic Channel plans to air 10 episodes of "StarTalk" for the first season. The show is scheduled to air new episodes on Mondays at 11 p.m. ET/10 p.m. CT, with reruns re of those episodes airing on Fridays at 7 p.m. ET/6 p.m. CT. Each episode will feature different interview guests and co-hosts. Upcoming interview guests include "Interstellar" director Christopher Nolan (April 27), astronaut Chris Hadfield (June 1) and NASA Administrator Charles Bolden (June 15). Guest hosts will include Janna Levin, professor of astronomy and physics at Columbia University (April 27), and astronaut Mike Massimino (June 1).

StarTalk is Tyson's second foray into television — he is also the host of "Cosmos: A Spacetime Odyssey," which is an updated version of the 1980 series "Cosmos: A Personal Voyage," hosted by Carl Sagan.

"StarTalk" will debut tonight on the National Geographic Channel at 11 p.m. EDT/10 p.m. CDT. Check local listings.

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