One expert testified that his research showed as many as 15,000 cases of breast cancer per year occurred in women taking the combination hormone drug. Yet the "defense witnesses told you the same thing, the same story line, that Wyeth wanted them to tell you over and over  that no one knows what causes breast cancer," said Russell T. Abney, another attorney representing Okuda. "We are not arguing that Ms. Okuda didn't have an abnormal cell in her body. What we are arguing is that [estrogen plus progesterone] promoted that abnormal cell to grow."