US Senator Bernie Sanders. REUTERS/Lucy Nicholson

On Wednesday night, Democratic presidential candidate Bernie Sanders announced a proposal to dramatically shift marijuana policy in the United States.

At a campaign stop in Virginia, Sen. Sanders announced he would be proposing new legislation in the coming weeks to remove cannabis from the list of Controlled Substances—a move many call “descheduling.”

In many ways, this would be the most aggressive change—short of national legalization—that Congress could make, and Sanders is the most prominent official in the United States to support such a move.

There is a bit we know about what this proposal could mean, and there is much we don’t quite yet know. Let’s break down each.

What do we know about Sanders’ descheduling proposal?