Python reticulatus, is the largest snake native to Asia. In several range countries it is hunted for its skin, for use in traditional medicine and for sale as a pet.

Wildlife Alliance forest guards from Pangolin patrol station (Stung Proat) rescued a Python reticulatus from the illegal wildlife trade. The snake was hidden by the poacher inside his motorbike. The man was fined with 250 USD. The rangers released the Python back to his habitat.

As with all pythons, the reticulated python is an ambush hunter, usually waiting until prey wanders within strike range before seizing it in its coils and killing by constriction. Its natural diet includes mammals and occasionally birds. Small specimens up to 3–4 m (9.8–13.1 ft) long eat mainly rodents such as rats, whereas larger individuals switch to prey such as small Indian civet and binturong, primates and pigs weighing more than 60 kg (130 lb). As a rule, the reticulated python seems able to swallow prey up to one-quarter its own length and up to its own weight. Near human habitation, it is known to snatch stray chickens, cats, and dogs on occasion.