Description

Aromasin 25mg

Buy Aromasin 25mg

Aromasin 25mg Tablet is used in the treatment of early stage breast cancer in postmenopausal women and in women who have already been treated with tamoxifen for 2 to 3 years without much clinical response. Patients with vitamin D deficiency are advised to take vitamin D supplements during treatment with this medicine.

Aromasin 25mg Composition

Exemestane

Aromasin 25mg Company Name

Pfizer Ltd.

Aromasin 25mg How To Work

Aromasin 25mg Tablet is an aromatase inhibitor. It works by lowering the amount of estrogen (natural female hormone) produced in the body. This can lower or stop the growth of some breast cancer cells that need estrogen to grow.

What Is Aromasin 25mg

Aromasin 25mg Tablet is a medication prescribed for the treatment of breast cancer. Aromasin 25mg Tablet belongs to a family of anti-estrogens and is mostly used to arrest the synthesis of estrogen by the release of an enzyme known as aromatase. Certain types of breast cancer are ER-positive and have estrogen receptors that require estrogen to grow and spread. Therefore it is important to lower the estrogen levels to decelerate the spread of the hormone-responsive cancer. The drug may also be used to treat advanced stages of breast cancer in postmenopausal women, where there has been a consistent progress in the disease following tamoxifen therapy.

Aromasin 25mg Tablet is mostly used to treat women who have reached menopausal years, with early symptoms of hormone-receptor-positive breast cancer. However the medication is contraindicated in pregnant, premenopausal or lactating women.

Common side effects of Aromasin 25mg Tablet include severe joint pain, headaches, hot flashes and excessive sweating which are typical symptoms of estrogen deficiency, as caused by the drug. Patients of breast cancer also exhibit symptoms of exhaustion and nausea. Sudden outbreaks of acne or weight gain are also associated with the dosage of the drug. Aromasin 25mg Tablet is known to have androgenic properties like that of formestane, and may also cause a decline in lymphocytes.

Aromasin 25mg How To Take

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Aromasin 25 mg Tablet is to be taken with food.

Mechanism Action Of Aromasin 25mg

Aromasin tablets 25mg contain exemestane, which is a potent and highly selective inhibitor of aromatase, an enzyme that is involved in the biosynthesis of the female hormone oestrogen. In premenopausal women the primary source of oestrogen production are the ovaries and it is involved in producing secondary sexual characteristics, such as breast development and in regulating the menstrual cycle.

In postmenopausal women, when oestrogen production by the ovaries ceases, low levels of oestrogen are made in peripheral tissues, such as fat cells throughout the body, also some breast cancer cells, by conversion of androstenedione (produced by the adrenal glands) to estrone, due to the action of aromatase and then by further conversion to oestradiol (the most active form of circulating oestrogen).

Many breast cancers have oestrogen receptors and their growth is stimulated by oestrogen; low levels of oestrogen may be sufficient to maintain growth of these tumour cells in women with breast cancer. Exemestane in Aromasin tablets 25mg blocks the action of aromatase, preventing the formation of oestrogen and helping to prevent growth of oestrogen-dependent breast tumours.

Aromasin 25mg Side Effects

Insomnia (difficulty in sleeping)

Headache

Nausea

Increased sweating

Musculoskeletal (bone

muscle or joint) pain

Aromasin 25mg Warning

Exemestane should only be used in women who have reached menopause and cannot become pregnant. You should confirm your post-menopausal status through hormonal tests (LH, FSH and estradiol levels) before starting exemestane therapy.

Exemestane should not be co-administered with estrogen-containing medications (such as hormone replacement therapy or birth control pills) as these can interfere with its action.

Regular examinations to monitor reductions in bone mineral density and elevations in certain blood tests (AST, ALT, alkaline phosphatase and gamma glutamyl transferase, bilirubin, creatinine) are recommended in women receiving exemestane.

Take precautions while driving or operating machinery as exemestane is known to cause drowsiness, sleepiness (somnolence), weakness (asthenia) and dizziness.

Aromasin 25mg Precaution

Reduction in bone mineral density (BMD) – This medicine may decrease bone mineral density (BMD). The bone mineral density should be assessed prior to initiating the treatment. Routine monitoring of BMD, appropriate corrective measures, or replacement with a suitable alternative may be required based on the clinical condition.

Vitamin D deficiency – Aromasin 25 mg Tablet may cause vitamin D deficiency. The level of 25-hydroxy vitamin D should be assessed prior to initiating the treatment. Routine monitoring of vitamin D levels, appropriate corrective measures, or replacement with a suitable alternative may be required based on the clinical condition.

Co-administration with estrogen containing products – This medicine is not recommended for use along with estrogen containing products since these products may alter the effects of the medicine and vice versa.

Use in premenopausal women – This medicine is not indicated for use in premenopausal women.

Sports – Use of this medicine during sports events is prohibited by World Anti-Doping Agency (WADA).

Pregnancy – This medicine is not recommended for use in pregnant women.

Breast-feeding – This medicine is not recommended for use in breastfeeding women.

Aromasin 25mg Dosage

Aromasin 25mg

Aromasin 25mg Uses

Aromasin 25mg Tablet is used in the treatment of breast cancer.

Aromasin 25mg Storage

Do not store your tablets above 30°C and keep them in the original pack.

Before use, check the expiry date printed on the pack. Do not use after this date.

Return all unused tablets to your pharmacist for disposal.

Keep out of the sight and reach of children.

If your doctor tells you to stop taking the tablets, please take them back to the pharmacist for safe disposal. Only keep the tablets if your doctor tells you to.

If the tablets become discoloured or show signs of any deterioration, you should seek the advice of your pharmacist who will advise you what to do.

Aromasin 25mg Review

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