Rambo III, set in Afghanistan, was dedicated to the Mujahideen pre-2001

The fifth Rambo film will be set in 'ISIS strongholds' in Iraq and Syria

Stallone is writing the screenplay and his team are scouting for locations

Rambo will fight ISIS in the next film, Sylvester Stallone has revealed

Sylvester Stallone is set to take on ISIS with the next Rambo movie, the Hollywood legend has revealed.

The fifth installment about troubled Vietnam War veteran John Rambo will see him fight 'global terrorism' in the Middle East.

According to Stallone, who is writing the script as well as repeating his role as Rambo, his production team is already scouting for locations in 'ISIS strongholds' in Syria and Iraq.

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Fighting terrorism: Sylvester Stallone's iconic film hero John Rambo will fight ISIS in Syria and Iraq in the upcoming, and final, film, the actor has revealed

The 68-year-old actor made the revelations during an unannounced appearance at San Diego Comic-Con last week to promote the next Rocky movie.

During a Q&A session about Creed, the upcoming film which sees Stallone repeat the role of Rocky Balboa for a seventh time, a fan interrupted with a question about Rambo V.

'We are working on it right now actually,' Stallone said, according to the Washington Times.

'We have teams scouting Iraq and parts of Syria where ISIS have their greatest strongholds. We're working with the locals there to help deliver the most intense and realistic Rambo movie experience ever.'

Although several members of the audience tried to ask follow-up questions, the actor refused to divulge any further information about the film, which has the working title 'Rambo: Last Blood'.

Back again: Last Blood will see Stallone, pictured in the first Rambo film First Blood in 1982, fight 'global terrorism' in the Middle East

New project: Stallone, pictured with his daughters in LA last week, has been working on the script since last year and has a production team scouting for locations in Syria and Iraq

A statement released in June last year appear to confirm that the ISIS line is not something Stallone made up on the spot at Comic Con.

'With Rambo V, Sylvester Stallone returns in his iconic role as John Rambo. This time he returns to the Middle East to battle the greatest threat facing the world today, global terrorism,' the statement by German movie company Splendor Films read.

This is not the first time the former U.S. Army Special Forces soldier flies in to fight in the Middle East.

The third installment, released in 1988, sees John Rambo travel on a solo-mission to Afghanistan during the Soviet-Afghan War, to rescue his old Vietnam commanding officer.

Real life on film: According to Stallone, he is working with locals near ISIS strongholds to 'help deliver the most intense and realistic Rambo movie experience ever'

Up until 2001, the film ended with the quote; 'This film is dedicated to the brave Mujahideen fighters of Afghanistan'.

After the September 11 attacks and the subsequent war in Afghanistan which saw many Mujhahideen fighters ally themselves with al-Qaeda, the dedication was changed to 'the gallant people of Afghanistan'.

Stallone is currently promoting Creed, the seventh Rocky Balboa movie, which will focus on Adonis Creed, the son of Rocky's one-time nemesis, Apollo.