Bonnie Franklin, whose portrayal of a pert but determined Ann Romano on the television show “One Day at a Time” in the 1970s and ’80s spun laughter out of the tribulations of a divorced woman juggling parenting, career, love life and feminist convictions, died on Friday at her home in Los Angeles. She was 69.

The cause was complications of pancreatic cancer, family members said. They had announced the diagnosis in September.

Ms. Franklin also acted on the stage and in movies and for years sang and danced in a nightclub act. But she was most widely known in the role of Ann Romano, one of the first independent women to be portrayed on TV wrestling with issues like sexual harassment, rape and menopause. Ms. Franklin — green-eyed, red-haired, button-nosed and 5-foot-3 — brought a buoyant comic touch to the part.

Some saw the show as helping feminism enter the mainstream.

“I know it’s just a television show, and I don’t think that I am changing the way the world is structured,” Ms. Franklin told The Washington Post in 1980, but she allowed that “sometimes we strike chords that do make people think a bit.”