New York Jets quarterback Geno Smith's broken jaw, which will put him out of action 6-10 weeks, means the Indianapolis Colts will likely face quarterback Ryan Fitzpatrick when the two teams meet at Lucas Oil Stadium on Sept. 21.

Smith's jaw was broken when backup linebacker IK Enemkpali sucker-punched him Tuesday. Geno Smith, right, will have to look on as Ryan Fitzpatrick likely takes the reins against the Indianapolis Colts. Julio Cortez/AP Photo

The Colts have faced Fitzpatrick two times in his career. He's 18-of-29 for 242 yards and a touchdown against them in those games. It also should be noted that the Colts have sacked Fitzpatrick five times in the two games. Fitzpatrick's 2014 season ended when he broke his leg while scrambling in a game against the Colts last December.

The Jets aren't the only team the Colts will face early in the season who will be without a starter. The Buffalo Bills, who the Colts face in Week 1, will be without defensive tackle Marcell Dareus for that game because he'll be serving his one-game suspension for violating the NFL"s substance-abuse policy. Dareus had nine sacks last season.