Brace yourself if any of your trips inside Loop 610 this weekend involve Interstate 10 or Interstate 45, and possibly consider extra time or additional routes.

Transportation officials are warning drivers that two major closings could complicate freeway travel, starting downtown when crews will close northbound I-45 from I-10 to Quitman at 5 a.m. Saturday.

Along with I-45 northbound lanes, the connection from westbound I-10, the westbound exit at Taylor and the I-45 entrance from Travis will be closed, officials said.

The work is related to improvements along White Oak Bayou.

I-45 CONSTRUCTION: Yes, the Gulf Freeway is going to close for another weekend

Northbound I-45 and the ramps will reopen at 9 p.m., but then close again from 5 a.m. to 9 p.m. Sunday.

West of I-45, the I-10 east and west connections to Loop 610 will close at 7 p.m. Saturday so crews can make a long-awaited traffic switch to a direct connection between I-10 and U.S. 290.

Along with alternating closings on Loop 610 from I-10 to Old Katy Road and reduced access to U.S. 290, officials are advising drivers to avoid the area if possible.

MORE INFORMATION: Big shift this weekend will smooth Loop/290 interchange

A host of other lane closings and detours will complicate other trips, including the closing of eastbound U.S. 290 from Hollister to Tidwell and the closing of northbound I-45 from FM 518 to El Dorado.

For specifics and other closings, go to Houston TranStar.