The former chairman of the Florida Republican Party on Thursday issued a scathing rebuke of President Trump Donald John TrumpOmar fires back at Trump over rally remarks: 'This is my country' Pelosi: Trump hurrying to fill SCOTUS seat so he can repeal ObamaCare Trump mocks Biden appearance, mask use ahead of first debate MORE, calling him “despicable” and “social poison.”

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Al Cardenas, a frequent Trump critic, tweeted his comment in response to the president's new campaign ad on immigration.

“You are a despicable divider; the worse social poison to afflict our country in decades,” Cardenas tweeted in a post that has since been deleted. “This ad, and your full approval of it, will condemn you and your bigoted legacy forever in the annals of America’s history books.”

The campaign ad that Cardenas referred to in his tweet features clips from the expletive-laden trial of Luis Bracamontes, a deported Mexican man who returned to the U.S. and killed two sheriff’s deputies in 2014. It also shows sometimes violent footage of crowds of migrants.

“Democrats let him stay … Who else would Democrats let in?” the ad asks.

Democratic National Committee Chairman Tom Perez Thomas Edward PerezClinton’s top five vice presidential picks Government social programs: Triumph of hope over evidence Labor’s 'wasteful spending and mismanagement” at Workers’ Comp MORE blasted the ad in an interview on Wednesday, calling it the "dog-whistle of all dog-whistles."

Cardenas, a lawyer and lobbyist who also served as a political appointee in the Reagan and George H. W. Bush administrations and as chairman of the American Conservative Union, was a top adviser to Jeb Bush’s presidential campaign.

Cardenas is considered one of the most influential Latino Republicans.