Here come the sequins, stilettos and big hair — Wigstock is back!

After more than a decade’s absence, the iconic counterculture drag festival returns Saturday to South Street Seaport’s Pier 17.

Granted, drag is more polished and accessible these days, thanks in part to reality TV’s “RuPaul’s Drag Race.” But Neil Patrick Harris — who launched this revival with his husband, David Burtka, and festival founder Lady Bunny — promises to take Wigstock back to its nutty roots.

“We are trying to create a big, giant tossed salad of drag fun,” the actor tells The Post. “And I don’t know what fan of drag doesn’t like a big tossed salad!”

The eight-hour extravaganza will feature a Who’s Who of drag and cabaret acts: Lypsinka, Joey Arias, Justin Vivian Bond, Murray Hill, Sherry Vine and Amanda Lepore among them. There will also be a few “Drag Race” alumni, including Season 6 winner Bianca Del Rio and Season 8 winner Bob the Drag Queen.

“You’ll get a little taste of everything,” Burtka says, “from punk bands to comedy to lip syncing to DJs to dance routines.”

Lady Bunny, a k a Tennessee native Jon Ingle, started the ball rolling in 1984, with an impromptu, late-night performance by drag queens in Tompkins Square Park for an audience of homeless people.

“I wanted to showcase drag talent from the Pyramid Club, Boy Bar, the theater,” she recalls. “I thought New York drag was reaching a zenith and could reach a bigger audience than the 250 people that would fit in Pyramid Club.”

Wigstock was “nothing to write home about” when it officially kicked off a year later, in the same East Village park. “We had no advertising budget. There were Xeroxed posters — remember Xerox?” says the 56-year-old Lady Bunny, laughing. “And that was before we even knew how to Photoshop our pictures, though we were younger then and didn’t need it as much.” Even so, she says, by day’s end, the event had filled the park.

For the next 16 years, Wigstock attracted thousands as it bounced between Tompkins Square, Union Square and the piers off Christopher Street. After 2001, though, the festival appeared sporadically and in abbreviated form, often in conjunction with other events.

Through the years, it welcomed talent like RuPaul, Boy George, Deee-Lite, Crystal Waters, Ultra Naté and Blondie’s Debbie Harry, who appeared many times.

Lady Bunny says one of her favorite moments came in 1998, when she joined CeCe Peniston onstage for a thumping version of her club hit “Finally.”

“When you heard that bass line, the crowd was just bouncing and shaking and celebrating,” she says. “I thought the pier was going to break off into the water!”

Past audiences have dolled up nearly as much as the performers, and Lady Bunny hopes Saturday’s crowd will, too. “We encourage people to put a wig on or come in a costume. It creates a carnivale atmosphere,” she says. “The audience is more prone to party along with us and is often as entertaining as the performers onstage.”

There will also be a tribute to Aretha Franklin, who was laid to rest on Friday. Lady Bunny says that former “Drag Race” contestant Latrice Royale, who can transform herself into the Queen of Soul, is planning a “rousing” shout-out. There will also be several salutes to gay icon Patti LaBelle.

“After we lost Aretha, I said, ‘You know what?’” Lady Bunny recalls. “‘Let’s celebrate our divas while they’re with us.’”

One Wigstock original making her return is transgender dancer and actress Candis Cayne. During one 1995 performance — a handspring-filled routine set to the Toni Basil hit “Mickey” — a dozen backup dancers dressed as cheerleaders hoisted her high into the air in a “basket toss.”

Don’t expect to see her do that again.

“I haven’t done a back handspring since then,” Cayne, 47, says with a laugh. “I’m not gonna enjoy it now!”

Harris — who cross-dressed his way to a Tony Award in 2014’s “Hedwig and the Angry Inch” — is eager to relive the gritty drag days of old.

Playing the title role in John Cameron Mitchell’s musical gave the former “Doogie Howser, MD” star a new respect for drag performers, and the “challenging, somewhat masochistic and specific” decisions they make to be beautiful.

Harris says he also wants to salute longtime artists who haven’t gotten the Instagram likes their “Drag Race” contemporaries have enjoyed.

And he just may slip on Hedwig’s gold stiletto boots on Saturday — along with a few other things.

“Yeah, I think Hedwig may return in all her glory,” he tells The Post. “I’ll be clutching pearls — and a Tony.”

Saturday, 2 to 10 p.m., Pier 17 at South Street Seaport, 89 South St.; tickets $95 and up; Wigstock.NYC