Wood has been placed on injured reserve after suffering a torn ACL during Sunday's game against the Titans, ESPN reports.

Wood's season-ending injury further depletes the Bills' banged-up backfield, as starting running back LeSean McCoy (hamstring) and rookie backup Karlos Williams (concussion) were already both inactive Sunday. With those absentees, Anthony Dixon and Dan Herron represent the only healthy tailbacks on Buffalo's current roster ahead of Sunday's Week 6 game against the Bengals.