Conservative columnist Bill Kristol, who has helped to spearhead the Never Trump movement, said on Friday that the GOP may have to be replaced after Donald Trump Donald John TrumpUS reimposes UN sanctions on Iran amid increasing tensions Jeff Flake: Republicans 'should hold the same position' on SCOTUS vacancy as 2016 Trump supporters chant 'Fill that seat' at North Carolina rally MORE inflicts irreparable damage.

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"I now wonder whether the Republican Party itself doesn't get so tainted by Trump that you don't have to think about the possibility of a new party or a really radically somehow revised or reformed party," he said on ABC’s “Powerhouse Politics” podcast, as reported by the Washington Examiner.

Kristol, who unsuccessfully tried to draft conservative blogger David French for a third-party candidacy, said that the GOP will lose out on crucial young voters because of Trump, the presumptive GOP presidential nominee.

"Is any American under 35 [going to] be interested in the Republican Party after four or five months of Trump as its spokesman?" he said.