Hepburn Avenue has reopened to traffic after a bomb scare involving a vehicle stopped at a booze bus caused the street to be locked-down for two hours.

Witness accounts claimed a vehicle crashed into the booze bus and flipped around 2.30pm with police condoning off the area and telling pedestrians there was a bomb in the vehicle.

A man has been charged after police found a bomb on the back seat of his car on Hepburn Avenue on Friday. Credit:Phil Hilton

A police spokeswoman, however, said the vehicle involved in the incident did not crash into the booze bus, but was searched after the 25-year-old driver returned a positive road-side drug test.

"A red vehicle has been stopped, there is concern about something in the vehicle," she said.