WASHINGTON — An officer for the Central Intelligence Agency was killed on Saturday in a suicide bombing in southern Afghanistan, American officials said Tuesday.

The attack, which was carried out in a remote area of Kandahar Province, occurred when a guard working for the Afghan intelligence service detonated a suicide vest as a delegation of American coalition members and Afghan intelligence officials arrived at the intelligence office in the Maruf District.

The blast killed Ghulam Rasool, the deputy intelligence director for Kandahar Province, two of his bodyguards, another Afghan intelligence official, and some Americans, including the C.I.A. officer.

An official with the NATO-led International Security Assistance Force said that the Americans did not appear to have been the principal targets but were “in the wrong place at the wrong time.” A spokeswoman for the C.I.A. declined to comment.