Journal Updates

Sublingual Immunotherapy Safe, Effective for Peanut Allergy

Peanut sublingual immunotherapy (SLIT) given in extended therapy up to 5 years provides significant desensitization for most peanut-allergic children, and is easy to use and safe, say the authors of a small study published online September 4 in the Journal of Allergy and Clinical Immunology.

Investigators noted that 67% of the 48 patients in the open-label extension study who received 2 mg/day of peanut protein under the tongue for 5 years were able to tolerate at least 750 mg of peanut protein without serious side effects. About 25% of patients could tolerate 5000 mg.