Mansfield K.E.

Sim J.

Jordan J.L.

Jordan K.P. A systematic review and meta-analysis of the prevalence of chronic widespread pain in the general population. Pain. 157 : 55-64 View in Article Scopus (64)

PubMed

Crossref

Google Scholar

Keohane J.

O’Mahony C.

O’Mahony L.

O’Mahony S.

Quigley E.M.

Shanahan F. Irritable bowel syndrome–type symptoms in patients with inflammatory bowel disease: a real association or reflection of occult inflammation?. Am J Gastroenterol. 105 : 1789-1794 View in Article Scopus (0)

Crossref

Google Scholar

Minderhoud I.M.

Oldenburg B.

Wismeijer J.A.

Henegouwen G.P.

Smout A. IBS-like symptoms in patients with inflammatory bowel disease in remission; relationships with quality of life and coping behavior. Dig Dis Sci. 49 : 469-474 View in Article Scopus (171)

PubMed

Crossref

Google Scholar

Halpin S.J.

Ford A.C. Prevalence of symptoms meeting criteria for irritable bowel syndrome in inflammatory bowel disease: systematic review and meta-analysis. Am J Gastroenterol. 107 : 1474-1482 View in Article Scopus (251)

PubMed

Crossref

Google Scholar

Simrén M.

Törnblom H.

Palsson O.S.

van Tilburg M.A.

Oudenhove L.

Tack J.

Whitehead W.E. Visceral hypersensitivity is associated with GI symptom severity in functional GI disorders: consistent findings from five different patient cohorts. Gut. 67 : 255-262 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Amadesi S.

Cottrell G.S.

Divino L.

Chapman K.

Grady E.F.

Bautista F.

Karanjia R.

Barajas-Lopez C.

Vanner S.

Vergnolle N.

Bunnett N.W. Protease-activated receptor 2 sensitizes TRPV1 by protein kinase Cɛ- and A-dependent mechanisms in rats and mice. J Physiol. 575 : 555-571 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Obreja O.

Biasio W.

Andratsch M.

Lips K.

Rathee P.

Ludwig A.

Rose-John S.

Kress M. Fast modulation of heat-activated ionic current by proinflammatory interleukin 6 in rat sensory neurons. Brain. 128 : 1634-1641 View in Article Scopus (84)

PubMed

Crossref

Google Scholar

Li J.

McRoberts J.A.

Ennes H.S.

Trevisani M.

Nicoletti P.

Mittal Y.

Mayer E.A. Experimental colitis modulates the functional properties of NMDA receptors in dorsal root ganglia neurons. Am J Physiol Gastrointest Liver Physiol. 291 : G219-G228 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Sung B.

Lim G.

Mao J. Altered expression and uptake activity of spinal glutamate transporters after nerve injury contribute to the pathogenesis of neuropathic pain in rats. J Neurosci. 23 : 2899-2910 View in Article PubMed

Crossref

Google Scholar

Jones C.R.

Xu L.

Gebhart G. The mechanosensitivity of mouse colon afferent fibers and their sensitization by inflammatory mediators require transient receptor potential vanilloid 1 and acid-sensing ion channel 3. J Neurosci. 25 : 10981-10989 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Akbar A.

Yiangou Y.

Facer P.

Walters J.

Anand P.

Ghosh S. Increased capsaicin receptor TRPV1-expressing sensory fibers in irritable bowel syndrome and their correlation with abdominal pain. Gut. 57 : 923-929 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Ren T.-H.

Wu J.

Yew D.

Ziea E.

Lao L.

Leung W.-K.

Berman B.

Hu P.-J.

Sung J.J. Effects of neonatal maternal separation on neurochemical and sensory response to colonic distension in a rat model of irritable bowel syndrome. Am J Physiol Gastrointest Liver Physiol. 292 : G849-G856 View in Article Scopus (84)

PubMed

Crossref

Google Scholar

Drewes A.

Frkjær J.

Larsen E.

Reddy H.

Arendt-Nielsen L.

Gregersen H. Pain and mechanical properties of the rectum in patients with active ulcerative colitis. Inflamm Bowel Dis. 12 : 294-303 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Larauche M.

Bradesi S.

Million M.

McLean P.

Taché Y.

Mayer E.A.

McRoberts J.A. Corticotropin-releasing factor type 1 receptors mediate the visceral hyperalgesia induced by repeated psychological stress in rats. Am J Physiol Gastrointest Liver Physiol. 294 : G1033-G1040 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Cairns B.E.

Arendt-Nielsen L.

Sacerdote P. Perspectives in pain research 2014: neuroinflammation and glial cell activation: the cause of transition from acute to chronic pain?. Scand J Pain. 6 : 3-6 View in Article PubMed

Crossref

Google Scholar

Coyle D.E. Partial peripheral nerve injury leads to activation of astroglia and microglia which parallels the development of allodynic behavior. Glia. 23 : 75-83 View in Article Scopus (263)

PubMed

Crossref

Google Scholar

Sweitzer S.M.

Colburn R.W.

Rutkowski M.

DeLeo J.A. Acute peripheral inflammation induces moderate glial activation and spinal IL-1β expression that correlates with pain behavior in the rat. Brain Res. 829 : 209-221 View in Article Scopus (281)

PubMed

Crossref

Google Scholar

Tanga F.

Raghavendra V.

DeLeo J. Quantitative real-time RT-PCR assessment of spinal microglial and astrocytic activation markers in a rat model of neuropathic pain. Neurochem Int. 45 : 397-407 View in Article Scopus (286)

PubMed

Crossref

Google Scholar

Brown I.A.

Gulbransen B.D. The antioxidant glutathione protects against enteric neuron death in situ, but its depletion is protective during colitis. Am J Physiol Gastrointest Liver Physiol. 314 : G39-G52 View in Article Scopus (2)

PubMed

Crossref

Google Scholar

Grubišić V.

Gulbransen B.D. Enteric glial activity regulates secretomotor function in the mouse colon but does not acutely affect gut permeability. J Physiol. 595 : 3409-3424 View in Article Scopus (24)

PubMed

Crossref

Google Scholar

Romero-Sandoval A.

Chai N.

Nutile-McMenemy N.

DeLeo J.A. A comparison of spinal Iba1 and GFAP expression in rodent models of acute and chronic pain. Brain Res. 1219 : 116-126 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Zhong Y.

Zhou L.-J.

Ren W.-J.

Xin W.-J.

Li Y.-Y.

Zhang T.

Liu X.-G. The direction of synaptic plasticity mediated by C-fibers in spinal dorsal horn is decided by Src-family kinases in microglia: the role of tumor necrosis factor-α. Brain Behav Immun. 24 : 874-880 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Gao Y.

Zhang L.

Glia J.R. Spinal injection of TNF-α-activated astrocytes produces persistent pain symptom mechanical allodynia by releasing monocyte chemoattractant protein-1. Glia. 58 : 1871-1880 View in Article Scopus (64)

PubMed

Crossref

Google Scholar

Sun Y.-N.

Luo J.-Y.

Rao Z.-R.

Lan L.

Duan L. GFAP and Fos immunoreactivity in lumbo-sacral spinal cord and medulla oblongata after chronic colonic inflammation in rats. World J Gastroenterol. 11 : 4827-4832 View in Article Scopus (14)

PubMed

Crossref

Google Scholar

Zhao P.

Waxman S.G.

Hains B.C. Modulation of thalamic nociceptive processing after spinal cord injury through remote activation of thalamic microglia by cysteine–cysteine chemokine ligand 21. J Neurosci. 27 : 8893-8902 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Jessen K.

Mirsky R. Astrocyte-like glia in the peripheral nervous system: an immunohistochemical study of enteric glia. J Neurosci. 3 : 2206-2218 View in Article PubMed

Crossref

Google Scholar

Cocchia D.

Michetti F.

Ferri G.-L.

Polak J.M.

Probert L.

Marangos P.J. Evidence for the presence of S-100 protein in the glial component of the human enteric nervous system. Nature. 297 : 409-410 View in Article Scopus (157)

PubMed

Crossref

Google Scholar

von Boyen G.B.

Steinkamp M.

Reinshagen M.

Schäfer K.H.

Adler G.

Kirsch J. Proinflammatory cytokines increase glial fibrillary acidic protein expression in enteric glia. Gut. 53 : 222-228 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Chen M.J.

Kress B.

Han X.

Moll K.

Peng W.

Ji R.

Nedergaard M. Astrocytic CX43 hemichannels and gap junctions play a crucial role in development of chronic neuropathic pain following spinal cord injury. Glia. 60 : 1660-1670 View in Article Scopus (103)

PubMed

Crossref

Google Scholar

Fried D.E.

Watson R.E.

Robson S.C.

Gulbransen B.D. Ammonia modifies enteric neuromuscular transmission through glial γ-aminobutyric acid signaling. Am J Physiol Gastrointest Liver Physiol. 313 : G570-G580 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Gulbransen B.D.

Bashashati M.

Hirota S.A.

Gui X.

Roberts J.A.

MacDonald J.A.

Muruve D.A.

McKay D.M.

Beck P.L.

Mawe G.M. Activation of neuronal P2X7 receptor–pannexin-1 mediates death of enteric neurons during colitis. Nat Med. 18 : 600-604 View in Article Scopus (202)

PubMed

Crossref

Google Scholar

Fujikawa Y.

Tominaga K.

Tanaka F.

Tanigawa T.

Watanabe T.

Fujiwara Y.

Arakawa T. Enteric glial cells are associated with stress-induced colonic hyper-contraction in maternally separated rats. Neurogastroenterol Motil. 27 : 1010-1023 View in Article Scopus (14)

PubMed

Crossref

Google Scholar

Gulbransen B.D.

Bains J.S.

Sharkey K.A. Enteric glia are targets of the sympathetic innervation of the myenteric plexus in the guinea pig distal colon. J Neurosci. 30 : 6801-6809 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Tjwa E.

Bradley J.M.

Keenan C.M.

Kroese A.

Sharkey K.A. Interleukin-1β activates specific populations of enteric neurons and enteric glia in the guinea pig ileum and colon. Am J Physiol Gastrointest Liver Physiol. 285 : G1268-G1276 View in Article PubMed

Crossref

Google Scholar

Rühl A.

Franzke S.

Collins Stremmel W. Interleukin-6 expression and regulation in rat enteric glial cells. Am J Physiol Gastrointest Liver Physiol. 280 : G1163-G1171 View in Article PubMed

Crossref

Google Scholar

Wang P.

Du C.

Chen F.-X.

Li C.-Q.

Yu Y.-B.

Han T.

Akhtar S.

Zuo X.-L.

Tan X.-D.

Li Y.-Q. BDNF contributes to IBS-like colonic hypersensitivity via activating the enteroglia-nerve unit. Sci Rep. 6 : 20320 View in Article Scopus (9)

PubMed

Crossref

Google Scholar

Berta T.

Park C.-K.

Xu Z.-Z.

Xie R.-G.

Liu T.

Lü N.

Liu Y.-C.

Ji R.-R. Extracellular caspase-6 drives murine inflammatory pain via microglial TNF-α secretion. J Clin Invest. 124 : 1173-1186 View in Article Scopus (84)

PubMed

Crossref

Google Scholar

Song D.

Li Y.

Tang D.

Huang L.

Yuan Y. Neuron-glial communication mediated by TNF-α and glial activation in dorsal root ganglia in visceral inflammatory hypersensitivity. Am J Physiol Gastrointest Liver Physiol. 306 : G788-G795 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Deiteren A.

van der Linden L.

de Wit A.

Ceuleers H.

Buckinx R.

Timmermans J.-P.

Moreels T.G.

Pelckmans P.A.

Man J.G.

Winter B.Y. P2x3 receptors mediate visceral hypersensitivity during acute chemically-induced colitis and in the post-inflammatory phase via different mechanisms of sensitization. PloS One. 10 : e0123810 View in Article Scopus (14)

PubMed

Crossref

Google Scholar

Lavoie E.G.

Gulbransen B.D.

Martín-Satué M.

Aliagas E.

Sharkey K.A.

Sévigny J. Ectonucleotidases in the digestive system: focus on NTPDase3 localization. Am J Physiol Gastrointest Liver Physiol. 300 : G608-G620 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Brisevac D.

Bajic A.

Bjelobaba I.

Milosevic M.

Stojiljkovic M.

Beyer C.

Clarner T.

Kipp M.

Nedeljkovic N. Expression of ecto-nucleoside triphosphate diphosphohydrolase1-3 (NTPDase1–3) by cortical astrocytes after exposure to pro-inflammatory factors in vitro. J Mol Neurosci. 51 : 871-879 View in Article Scopus (8)

PubMed

Crossref

Google Scholar

Tonkin R.S.

Bowles C.

Perera C.J.

Keating B.A.

Makker P.

Duffy S.S.

Lees J.G.

Tran C.

Don A.S.

Fath T.

Liu L.

O’Carroll S.J.

Nicholson L.

Green C.R.

Gorrie C.

Moalem-Taylor G. Attenuation of mechanical pain hypersensitivity by treatment with Peptide5, a connexin-43 mimetic peptide, involves inhibition of NLRP3 inflammasome in nerve-injured mice. Exp Neurol. 300 : 1-12 View in Article Scopus (15)

PubMed

Crossref

Google Scholar

Choi S.-R.

Roh D.-H.

Yoon S.-Y.

Kwon S.-G.

Choi H.-S.

Han H.-J.

Beitz A.J.

Lee J.-H. Astrocyte sigma-1 receptors modulate connexin 43 expression leading to the induction of below-level mechanical allodynia in spinal cord injured mice. Neuropharmacology. 111 : 34-46 View in Article PubMed

Crossref

Google Scholar

Scully P.

McKernan D.P.

Keohane J.

Groeger D.

Shanahan F.

Dinan T.G.

Quigley E.M. Plasma cytokine profiles in females with irritable bowel syndrome and extra-intestinal co-morbidity. Am J Gastroenterol. 105 : 2235-2243 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Sawa Y.

Oshitani N.

Adachi K.

Higuchi K.

Matsumoto T.

Arakawa T. Comprehensive analysis of intestinal cytokine messenger RNA profile by real-time quantitative polymerase chain reaction in patients with inflammatory bowel disease. Int J Mol Med. 11 : 175-179 View in Article PubMed

Google Scholar

Wen Y.-R.

Suter M.R.

Ji R.-R.

Yeh G.-C.

Wu Y.-S.

Wang K.-C.

Kohno T.

Sun W.-Z.

Wang C.-C. Activation of p38 mitogen-activated protein kinase in spinal microglia contributes to incision-induced mechanical allodynia. Anesthesiology. 110 : 155-165 View in Article Scopus (91)

PubMed

Crossref

Google Scholar

Takeda M.

Takahashi M.

Matsumoto S. Contribution of the activation of satellite glia in sensory ganglia to pathological pain. Neurosci Biobehav Rev. 33 : 784-792 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Takac B.

Mihaljević S.

Stefanić M.

Glavas-Obrovac L.

Kibel A.

Samardzija M. Importance of interleukin 6 in pathogenesis of inflammatory bowel disease. Coll Antropol. 38 : 659-664 View in Article PubMed

Google Scholar

DeLeo J.

Colburn R.

Nichols M.

Malhotra A. Interleukin-6-mediated hyperalgesia/allodynia and increased spinal IL-6 expression in a rat mononeuropathy model. J Interferon Cytokine Res. 16 : 695-700 View in Article PubMed

Crossref

Google Scholar

Okamoto K.

Martin D.P.

Schmelzer J.D.

Mitsui Y.

Low P.A. Pro- and anti-inflammatory cytokine gene expression in rat sciatic nerve chronic constriction injury model of neuropathic pain. Exp Neurol. 169 : 386-391 View in Article Scopus (167)

PubMed

Crossref

Google Scholar

Murphy P.

Ramer M.

Borthwick L.

Gauldie J.

Richardson P.

Bisby M. Endogenous interleukin-6 contributes to hypersensitivity to cutaneous stimuli and changes in neuropeptides associated with chronic nerve constriction in mice. Eur J Neurosci. 11 : 2243-2253 View in Article Scopus (165)

PubMed

Crossref

Google Scholar

Nozu T.

Miyagishi S.

Nozu R.

Takakusaki K.

Okumura T. Repeated water avoidance stress induces visceral hypersensitivity: role of interleukin-1, interleukin-6, and peripheral corticotropin-releasing factor. J Gastroenterol Hepatol. 32 : 1958-1965 View in Article Scopus (17)

PubMed

Crossref

Google Scholar

Liu Y.

Zhou L.-J.

Wang J.

Li D.

Ren W.-J.

Peng J.

Wei X.

Xu T.

Xin W.-J.

Pang R.-P.

Li Y.-Y.

Qin Z.-H.

Murugan M.

Mattson M.P.

Wu L.-J.

Liu X.-G. TNF-α differentially regulates synaptic plasticity in the hippocampus and spinal cord by microglia-dependent mechanisms after peripheral nerve injury. J Neurosci. 37 : 871-881 View in Article Scopus (20)

Crossref

Google Scholar

Liñán-Rico A.

Turco F.

Ochoa-Cortes F.

Harzman A.

Needleman B.J.

Arsenescu R.

Abdel-Rasoul M.

Fadda P.

Grants I.

Whitaker E.

Cuomo R.

Christofi F.L. Molecular signaling and dysfunction of the human reactive enteric glial cell phenotype: implications for GI infection, IBD, POI, neurological, motility, and GI disorders. Inflamm Bowel Dis. 22 : 1812-1834 View in Article Scopus (16)

PubMed

Crossref

Google Scholar

Siniscalco D.

Giordano C.

Rossi F.

Maione S.

de Novellis V. Role of neurotrophins in neuropathic pain. Curr Neuropharmacol. 9 : 523-529 View in Article PubMed

Crossref

Google Scholar

Xia C.-M.

Gulick M.A.

Yu S.J.

Grider J.R.

Murthy K.S.

Kuemmerle J.F.

Akbarali H.I.

Qiao L.-Y. Up-regulation of brain-derived neurotrophic factor in primary afferent pathway regulates colon-to-bladder cross-sensitization in rat. J Neuroinflamm. 9 : 30 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Levanti M.B.

Esteban I.

Ciriaco E.

Pérez-Piñera P.

Cabo R.

García-Suarez O.

Pardo B.

Silos-Santiago I.

Cobo J.

Vega J.A. Enteric glial cells express full-length TrkB and depend on TrkB expression for normal development. Neurosci Lett. 454 : 16-21 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Boyen V.G.

Steinkamp M.

Reinshagen M.

Schäfer K.-H.

Adler G.

Kirsch J. Nerve growth factor secretion in cultured enteric glia cells is modulated by proinflammatory cytokines. J Neuroendocrinol. 18 : 820-825 View in Article Scopus (38)

PubMed

Crossref

Google Scholar

Quigley E. The gut-brain axis and the microbiome: clues to pathophysiology and opportunities for novel management strategies in irritable bowel syndrome (IBS). J Clin Med. 7 : 6 View in Article Crossref

Google Scholar

Moloney R.D.

Johnson A.C.

O’Mahony S.M.

Dinan T.G.

Meerveld B.

Cryan J.F. Stress and the microbiota–gut–brain axis in visceral pain: relevance to irritable bowel syndrome. CNS Neurosci Ther. 22 : 102-117 View in Article PubMed

Crossref

Google Scholar

Ochoa-Cortes F.

Ramos-Lomas T.

Miranda-Morales M.

Spreadbury I.

Ibeakanma C.

Barajas-Lopez C.

Vanner S. Bacterial cell products signal to mouse colonic nociceptive dorsal root ganglia neurons. Am J Physiol Gastrointest Liver Physiol. 299 : G723-G732 View in Article Scopus (57)

PubMed

Crossref

Google Scholar

Husebye E.

Hellström P.

Midtvedt T. Intestinal microflora stimulates myoelectric activity of rat small intestine by promoting cyclic initiation and aboral propagation of migrating myoelectric complex. Dig Dis Sci. 39 : 946-956 View in Article Scopus (121)

PubMed

Crossref

Google Scholar

Kabouridis P.S.

Lasrado R.

McCallum S.

Chng S.H.

Snippert H.J.

Clevers H.

Pettersson S.

Pachnis V. The gut microbiota keeps enteric glial cells on the move; prospective roles of the gut epithelium and immune system. Gut Microbes. 6 : 398-403 View in Article PubMed

Crossref

Google Scholar

Xu S.

Qin B.

Shi A.

Zhao J.

Guo X.

Dong L. Oxytocin inhibited stress induced visceral hypersensitivity, enteric glial cells activation, and release of proinflammatory cytokines in maternal separated rats. Eur J Pharmacol. 818 : 578-584 View in Article Scopus (10)

PubMed

Crossref

Google Scholar

Chow A.K.

Gulbransen B.D. Potential roles of enteric glia in bridging neuroimmune communication in the gut. Am J Physiol Gastrointest Liver Physiol. 312 : G145-G152 View in Article Scopus (9)

PubMed

Crossref

Google Scholar

Bhave S.

Gade A.

Kang M.

Hauser K.F.

Dewey W.L.

Akbarali H.I. Connexin-purinergic signaling in enteric glia mediates the prolonged effect of morphine on constipation. FASEB J. 31 : 2649-2660 View in Article Scopus (17)

PubMed

Crossref

Google Scholar

Ceuleers H.

Spaendonk H.

Hanning N.

Heirbaut J.

Lambeir A.-M.

Joossens J.

Augustyns K.

Man J.G.

Meester I.

Winter B.Y. Visceral hypersensitivity in inflammatory bowel diseases and irritable bowel syndrome: The role of proteases. World J Gastroenterol. 22 : 10275-10286 View in Article Scopus (7)

PubMed

Crossref

Google Scholar

Barbara G.

Cremon C.

Giorgio R.

Dothel G.

Zecchi L.

Bellacosa L.

Carini G.

Stanghellini V.

Corinaldesi R. Mechanisms underlying visceral hypersensitivity in irritable bowel syndrome. Curr Gastroenterol Rep. 13 : 308-315 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Lis K.

Grygorowicz T.

Cudna A.

Szymkowski D.E.

Bałkowiec-Iskra E. Inhibition of TNF reduces mechanical orofacial hyperalgesia induced by Complete Freund’s Adjuvant by a TRPV1-dependent mechanism in mice. Pharmacol Rep. 69 : 1380-1385 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Utsumi D.

Matsumoto K.

Tsukahara T.

Amagase K.

Tominaga M.

Kato S. Transient receptor potential vanilloid 1 and transient receptor potential ankyrin 1 contribute to the progression of colonic inflammation in dextran sulfate sodium-induced colitis in mice: Links to calcitonin gene-related peptide and substance P. J Pharmacol Sci. 136 : 121-132 View in Article Scopus (3)

PubMed

Crossref

Google Scholar

Spencer N.J.

Magnúsdóttir E.I.

Jakobsson J.

Kestell G.

Chen B.N.

Morris D.

Brookes S.J.

Lagerström M.C. CGRPα within the Trpv1-Cre population contributes to visceral nociception. Am J Physiol Gastrointest Liver Physiol. 314 : G188-G200 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Mobarakeh J.

Torkaman-Boutorabi A.

Rahimi A.

Ghasri S.

Nezhad R.

Hamzely A.

Sima B.

Takahashi K.

Nunoki K.

Yanai K. Interaction of histamine and calcitonin gene-related peptide in the formalin induced pain perception in rats. Biomed Res. 32 : 195-201 View in Article Scopus (6)

PubMed

Crossref

Google Scholar

Yoshikawa T.

Naganuma F.

Iida T.

Nakamura T.

Harada R.

Mohsen A.S.

Kasajima A.

Sasano H.

Yanai K. Molecular mechanism of histamine clearance by primary human astrocytes. Glia. 61 : 905-916 View in Article Scopus (50)

PubMed

Crossref

Google Scholar

Kimball B.C.

Mulholland M.W. Enteric glia exhibit P2U receptors that increase cytosolic calcium by a phospholipase C-dependent mechanism. J Neurochem. 66 : 604-612 View in Article PubMed

Crossref

Google Scholar

Turco F.

Sarnelli G.

Cirillo C.

Palumbo I.

Giorgi F.

D’Alessandro A.

Cammarota M.

Giuliano M.

Cuomo R. Enteroglial-derived S100B protein integrates bacteria-induced Toll-like receptor signalling in human enteric glial cells. Gut. 63 : 105-115 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

da Silveira A.

de Oliveira E.C.

Neto S.G.

Luquetti A.O.

Fujiwara R.

Oliveira R.

Brehmer A. Enteroglial cells act as antigen-presenting cells in chagasic megacolon. Hum Pathol. 42 : 522-532 View in Article Scopus (15)

PubMed

Crossref

Google Scholar

Ibiza S.

García-Cassani B.

Ribeiro H.

Carvalho T.

Almeida L.

Marques R.

Misic A.M.

Bartow-McKenney C.

Larson D.M.

Pavan W.J.

Eberl G.

Grice E.A.

Veiga-Fernandes H. Glial-cell-derived neuroregulators control type 3 innate lymphoid cells and gut defence. Nature. 535 : 440-443 View in Article PubMed

Crossref

Google Scholar

Dunn K.

Saunders K.W.

Rutter C.M.

Banta-Green C.J.

Merrill J.O.

Sullivan M.D.

Weisner C.M.

Silverberg M.J.

Campbell C.I.

Psaty B.M.

Korff M. Opioid prescriptions for chronic pain and overdose: a cohort study. Ann Intern Med. 152 : 85-92 View in Article PubMed

Crossref

Google Scholar

Berta T.

Liu T.

Liu Y.C.

Xu Z.Z.

Ji R.R. Acute morphine activates satellite glial cells and up-regulates IL-1β in dorsal root ganglia in mice via matrix metalloprotease-9. Mol Pain. 8 : 18 View in Article Scopus (49)

PubMed

Crossref

Google Scholar

Zhou Z.

Peng X.

Hao S.

Fink D.J.

Mata M. HSV-mediated transfer of interleukin-10 reduces inflammatory pain through modulation of membrane tumor necrosis factor α in spinal cord microglia. Gene Ther. 15 : 183-190 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Hutchinson M.R.

Coats B.D.

Lewis S.S.

Zhang Y.

Sprunger D.B.

Rezvani N.

Baker E.M.

Jekich B.M.

Wieseler J.L.

Somogyi A.A.

Martin D.

Poole S.

Judd C.M.

Maier S.F.

Watkins L.R. Proinflammatory cytokines oppose opioid-induced acute and chronic analgesia. Brain Behav Immun. 22 : 1178-1189 View in Article Scopus (205)

PubMed

Crossref

Google Scholar

Hutchinson M.R.

Zhang Y.

Shridhar M.

Evans J.H.

Buchanan M.M.

Zhao T.X.

Slivka P.F.

Coats B.D.

Rezvani N.

Wieseler J.

Hughes T.S.

Landgraf K.E.

Chan S.

Fong S.

Phipps S.

Falke J.J.

Leinwand L.A.

Maier S.F.

Yin H.

Rice K.C.

Watkins L.R. Evidence that opioids may have toll-like receptor 4 and MD-2 effects. Brain Behav Immun. 24 : 83-95 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Beckett E.A.

Staikopoulos V.

Hutchinson M.R. Differential effect of morphine on gastrointestinal transit, colonic contractions and nerve-evoked relaxations in Toll-Like Receptor deficient mice. Sci Rep. 8 : 5923 View in Article Scopus (0)

PubMed

Crossref

Google Scholar

Eser A.

Colombel J.F.

Rutgeerts P.

Vogelsang H.

Braddock M.

Persson T.

Reinisch W. Safety and efficacy of an oral inhibitor of the purinergic receptor P2X7 in adult patients with moderately to severely active Crohn’s disease: a randomized placebo-controlled, double-blind, phase IIa study. Inflamm Bowel Dis. 21 : 2247-2253 View in Article PubMed

Google Scholar